메뉴 건너뛰기




Volumn 485, Issue 7399, 2012, Pages 517-521

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(19)  Fünfschilling, Ursula a   Supplie, Lotti M a   Mahad, Don b,h   Boretius, Susann c   Saab, Aiman S a,i   Edgar, Julia a   Brinkmann, Bastian G a,j,k   Kassmann, Celia M a   Tzvetanova, Iva D a   Möbius, Wiebke a   Diaz, Francisca d   Meijer, Dies e   Suter, Ueli f   Hamprecht, Bernd a   Sereda, Michael W a,g   Moraes, Carlos T d   Frahm, Jens c   Goebbels, Sandra a   Nave, Klaus Armin a  


Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; LACTIC ACID; MYELIN; PROTEIN FARNESYLTRANSFERASE; PROTOHEME IX FARNESYLTRANSFERASE; UNCLASSIFIED DRUG;

EID: 84861429431     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11007     Document Type: Article
Times cited : (1074)

References (32)
  • 1
    • 0032486428 scopus 로고    scopus 로고
    • Axonal swellings and degeneration in mice lacking the major proteolipid of myelin
    • Griffiths, I. et al. Axonal swellings and degeneration in mice lacking the major proteolipid of myelin. Science 280, 1610-1613 (1998).
    • (1998) Science , vol.280 , pp. 1610-1613
    • Griffiths, I.1
  • 2
    • 0037370361 scopus 로고    scopus 로고
    • Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination
    • Lappe-Siefke, C. et al. Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination. Nature Genet. 33, 366-374 (2003).
    • (2003) Nature Genet. , vol.33 , pp. 366-374
    • Lappe-Siefke, C.1
  • 3
    • 34547527078 scopus 로고    scopus 로고
    • Axonal loss and neuroinflammation caused by peroxisomedeficient oligodendrocytes
    • Kassmann, C. M. et al. Axonal loss and neuroinflammation caused by peroxisomedeficient oligodendrocytes. Nature Genet. 39, 969-976 (2007).
    • (2007) Nature Genet. , vol.39 , pp. 969-976
    • Kassmann, C.M.1
  • 4
    • 77949873025 scopus 로고    scopus 로고
    • Myelination and the trophic support of long axons
    • Nave, K. A.Myelination and the trophic support of long axons.Nature Rev. Neurosci. 11, 275-283 (2010).
    • (2010) Nature Rev. Neurosci. , vol.11 , pp. 275-283
    • Nave, K.A.1
  • 5
    • 78649364642 scopus 로고    scopus 로고
    • Injury and differentiation following inhibition of mitochondrial respiratory chain complex IV in rat oligodendrocytes
    • Ziabreva, I. et al. Injury and differentiation following inhibition of mitochondrial respiratory chain complex IV in rat oligodendrocytes. Glia 58, 1827-1837 (2010).
    • (2010) Glia , vol.58 , pp. 1827-1837
    • Ziabreva, I.1
  • 6
    • 27244442141 scopus 로고    scopus 로고
    • Transfer of glycogen-derived lactate from astrocytes to axons via specific monocarboxylate transporters supports mouse optic nerve activity
    • Tekkö k, S. B., Brown, A. M., Westenbroek, R., Pellerin, L. & Ransom, B. R. Transfer of glycogen-derived lactate from astrocytes to axons via specific monocarboxylate transporters supports mouse optic nerve activity. J. Neurosci. Res. 81, 644-652 (2005).
    • (2005) J. Neurosci. Res. , vol.81 , pp. 644-652
    • Tekkök, S.B.1    Brown, A.M.2    Westenbroek, R.3    Pellerin, L.4    Ransom, B.R.5
  • 7
    • 24944447977 scopus 로고    scopus 로고
    • Mice lackingCOX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochromec oxidase deficiency
    • Diaz, F., Thomas, C. K., Garcia, S., Hernandez, D.&Moraes, C. T. Mice lackingCOX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochromec oxidase deficiency.Hum.Mol.Genet.14, 2737-2748 (2005).
    • (2005) Hum.Mol.Genet. , vol.14 , pp. 2737-2748
    • Diaz, F.1    Thomas, C.K.2    Garcia, S.3    Hernandez, D.4    Moraes, C.T.5
  • 8
    • 0142154270 scopus 로고    scopus 로고
    • Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency
    • Antonicka, H. et al. Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency. Hum. Mol. Genet. 12, 2693-2702 (2003).
    • (2003) Hum. Mol. Genet. , vol.12 , pp. 2693-2702
    • Antonicka, H.1
  • 9
    • 38549100592 scopus 로고    scopus 로고
    • Pathophysiology and fate of hepatocytes in a mouse model of mitochondrial hepatopathies
    • Diaz, F. et al. Pathophysiology and fate of hepatocytes in a mouse model of mitochondrial hepatopathies. Gut 57, 232-242 (2008).
    • (2008) Gut , vol.57 , pp. 232-242
    • Diaz, F.1
  • 10
    • 35348923542 scopus 로고    scopus 로고
    • Cytochrome c oxidase deficiency in neurons decreases both oxidative stress andamyloid formation in amousemodel of Alzheimer's disease
    • Fukui, H., Diaz, F., Garcia, S. & Moraes, C. T. Cytochrome c oxidase deficiency in neurons decreases both oxidative stress andamyloid formation in amousemodel of Alzheimer's disease. Proc. Natl Acad. Sci. USA 104, 14163-14168 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 14163-14168
    • Fukui, H.1    Diaz, F.2    Garcia, S.3    Moraes, C.T.4
  • 11
    • 77954391902 scopus 로고    scopus 로고
    • Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination
    • Goebbels, S. et al. Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination. J. Neurosci. 30, 8953-8964 (2010).
    • (2010) J. Neurosci. , vol.30 , pp. 8953-8964
    • Goebbels, S.1
  • 12
    • 0037135989 scopus 로고    scopus 로고
    • Notch1 control of oligodendrocyte differentiation in the spinal cord
    • Genoud, S. et al. Notch1 control of oligodendrocyte differentiation in the spinal cord. J. Cell Biol. 158, 709-718 (2002).
    • (2002) J. Cell Biol. , vol.158 , pp. 709-718
    • Genoud, S.1
  • 13
    • 0022384311 scopus 로고
    • A quantitative immunohistochemical study ofmacroglial cell development in the rat optic nerve: In vivo evidence for two distinct astrocyte lineages
    • Miller, R. H., David, S., Patel, R., Abney, E. R. & Raff, M. C. A quantitative immunohistochemical study ofmacroglial cell development in the rat optic nerve: in vivo evidence for two distinct astrocyte lineages. Dev. Biol. 111, 35-41 (1985).
    • (1985) Dev. Biol. , vol.111 , pp. 35-41
    • Miller, R.H.1    David, S.2    Patel, R.3    Abney, E.R.4    Raff, M.C.5
  • 14
    • 0014217167 scopus 로고
    • Theturnover of the protein components of mitochondria from rat liver, kidney, and brain
    • Beattie, D. S.,Basford, R. E.&Koritz, S. B.Theturnover of the protein components of mitochondria from rat liver, kidney, and brain. J. Biol. Chem. 242, 4584-4586 (1967).
    • (1967) J. Biol. Chem. , vol.242 , pp. 4584-4586
    • Beattie, D.S.1    Basford, R.E.2    Koritz, S.B.3
  • 15
    • 0015239454 scopus 로고
    • The turnover of mitochondria in a variety of tissues of young adult and aged rats
    • Menzies, R. A. & Gold, P. H. The turnover of mitochondria in a variety of tissues of young adult and aged rats. J. Biol. Chem. 246, 2425-2429 (1971).
    • (1971) J. Biol. Chem. , vol.246 , pp. 2425-2429
    • Menzies, R.A.1    Gold, P.H.2
  • 16
    • 79960401668 scopus 로고    scopus 로고
    • Schwanncell mitochondrialmetabolismsupports long-termaxonal survival and peripheral nerve function
    • Viader, A. et al.Schwanncell mitochondrialmetabolismsupports long-termaxonal survival and peripheral nerve function. J. Neurosci. 31, 10128-10140 (2011).
    • (2011) J. Neurosci. , vol.31 , pp. 10128-10140
    • Viader, A.1
  • 17
    • 0142011184 scopus 로고    scopus 로고
    • Mitochondrial potassium transport: The K1 cycle
    • Garlid, K. D. & Paucek, P. Mitochondrial potassium transport: the K1 cycle. Biochim. Biophys. Acta 1606, 23-41 (2003).
    • (2003) Biochim. Biophys. Acta , vol.1606 , pp. 23-41
    • Garlid, K.D.1    Paucek, P.2
  • 18
    • 25644434410 scopus 로고    scopus 로고
    • Enhancing central nervous system remyelination in multiple sclerosis
    • Dubois-Dalcq, M., Ffrench-Constant, C. & Franklin, R. J. Enhancing central nervous system remyelination in multiple sclerosis. Neuron 48, 9-12 (2005).
    • (2005) Neuron , vol.48 , pp. 9-12
    • Dubois-Dalcq, M.1    Ffrench-Constant, C.2    Franklin, R.J.3
  • 19
    • 33745478725 scopus 로고    scopus 로고
    • Cytochrome c oxidase is required for the assembly/stability of respiratory complex i inmouse fibroblasts
    • Diaz, F., Fukui, H.,Garcia, S.&Moraes, C. T. Cytochrome c oxidase is required for the assembly/stability of respiratory complex I inmouse fibroblasts. Mol. Cell. Biol. 26, 4872-4881 (2006).
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 4872-4881
    • Diaz, F.1    Fukui, H.2    Garcia, S.3    Moraes, C.T.4
  • 20
    • 33947424365 scopus 로고
    • Evidence for a higher glycolytic than oxidative metabolic activity in white matter of rat brain
    • Moreland, C., Henjum, S., Iversen, E. G., Skredde, K. K. & Hassel, B. Evidence for a higher glycolytic than oxidative metabolic activity in white matter of rat brain. Neurochem. Int. 50, 703-709 (1990).
    • (1990) Neurochem. Int. , vol.50 , pp. 703-709
    • Moreland, C.1    Henjum, S.2    Iversen, E.G.3    Skredde, K.K.4    Hassel, B.5
  • 21
    • 0035577691 scopus 로고    scopus 로고
    • Metabolic substrates other than glucose support axonfunctionincentralwhitematter
    • Brown, A. M., Wender, R. & Ransom, B. R. Metabolic substrates other than glucose support axonfunctionincentralwhitematter. J.Neurosci.Res.66,839- 843(2001).
    • (2001) J.Neurosci.Res. , vol.66 , pp. 839-843
    • Brown, A.M.1    Wender, R.2    Ransom, B.R.3
  • 22
    • 70349337150 scopus 로고    scopus 로고
    • Astrocytes are poised for lactate trafficking and release from activated brain and for supply of glucose to neurons
    • Gandhi, G. K., Cruz, N. F., Ball, K. K. & Dienel, G. A. Astrocytes are poised for lactate trafficking and release from activated brain and for supply of glucose to neurons. J. Neurochem. 111, 522-536 (2009).
    • (2009) J. Neurochem. , vol.111 , pp. 522-536
    • Gandhi, G.K.1    Cruz, N.F.2    Ball, K.K.3    Dienel, G.A.4
  • 23
    • 0142084655 scopus 로고    scopus 로고
    • Developmental switch in brain nutrient transporter expression in the rat
    • Vannucci, S. J. & Simpson, I. A. Developmental switch in brain nutrient transporter expression in the rat.Am. J. Physiol. Endocrinol. Metab. 285, E1127-E1134 (2003).
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.285
    • Vannucci, S.J.1    Simpson, I.A.2
  • 24
    • 78651473295 scopus 로고    scopus 로고
    • Regulation of oligodendrocyte development andmyelination by glucose and lactate
    • Rinholm, J. E. et al.Regulation of oligodendrocyte development andmyelination by glucose and lactate. J. Neurosci. 31, 538-548 (2011).
    • (2011) J. Neurosci. , vol.31 , pp. 538-548
    • Rinholm, J.E.1
  • 25
    • 0018934198 scopus 로고
    • Immunocytochemical localization of glycerol-3-phosphate dehydrogenase in rat oligodendrocytes
    • Leveille, P. J., McGinnis, J. F., Maxwell, D. S. & de Vellis, J. Immunocytochemical localization of glycerol-3-phosphate dehydrogenase in rat oligodendrocytes. Brain Res. 196, 287-305 (1980).
    • (1980) Brain Res. , vol.196 , pp. 287-305
    • Leveille, P.J.1    McGinnis, J.F.2    Maxwell, D.S.3    De Vellis, J.4
  • 26
    • 24744452808 scopus 로고    scopus 로고
    • Reduced N-acetylaspartate levels in mice lacking aralar, a brainand muscle-type mitochondrial aspartate-glutamate carrier
    • Jalil, M. A. et al. Reduced N-acetylaspartate levels in mice lacking aralar, a brainand muscle-type mitochondrial aspartate-glutamate carrier. J. Biol. Chem. 280, 31333-31339 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 31333-31339
    • Jalil, M.A.1
  • 27
    • 0028080101 scopus 로고
    • Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization
    • Pellerin, L. & Magistretti, P. J. Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc. Natl Acad. Sci. USA 91, 10625-10629 (1994).
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 10625-10629
    • Pellerin, L.1    Magistretti, P.J.2
  • 28
    • 79952305803 scopus 로고    scopus 로고
    • Astrocyte-neuron lactate transport is required for long-term memory formation
    • Suzuki, A. et al. Astrocyte-neuron lactate transport is required for long-term memory formation. Cell 144, 810-823 (2011).
    • (2011) Cell , vol.144 , pp. 810-823
    • Suzuki, A.1
  • 29
    • 0038623319 scopus 로고    scopus 로고
    • The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development
    • Jaegle, M. et al. The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. Genes Dev. 17, 1380-1391 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 1380-1391
    • Jaegle, M.1
  • 30
    • 0037396606 scopus 로고    scopus 로고
    • Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells
    • Leone, D. P. et al. Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells. Mol. Cell. Neurosci. 22, 430-440 (2003).
    • (2003) Mol. Cell. Neurosci. , vol.22 , pp. 430-440
    • Leone, D.P.1
  • 31
    • 0033213270 scopus 로고    scopus 로고
    • Essential role for TrkB receptors in hippocampus-mediated learning
    • Minichiello, L. et al. Essential role for TrkB receptors in hippocampus-mediated learning. Neuron 24, 401-414 (1999).
    • (1999) Neuron , vol.24 , pp. 401-414
    • Minichiello, L.1
  • 32
    • 67349119492 scopus 로고    scopus 로고
    • Localized proton MRS of animal brain in vivo: Models of human disorders
    • Michaelis, T., Boretius, S. & Frahm, J. Localized proton MRS of animal brain in vivo: Models of human disorders. Prog. Nucl. Magn. Reson. Spectrosc. 55, 1-34 (2009).
    • (2009) Prog. Nucl. Magn. Reson. Spectrosc. , vol.55 , pp. 1-34
    • Michaelis, T.1    Boretius, S.2    Frahm, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.