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Volumn 17, Issue 4, 2008, Pages 602-616

Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN 37; CHAPERONE; HEAT SHOCK PROTEIN 90; PARKIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE INDUCED KINASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

EID: 38849155699     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddm334     Document Type: Article
Times cited : (133)

References (34)
  • 2
    • 33644610520 scopus 로고    scopus 로고
    • The genetics of Parkinson disease: Implications for neurological care
    • Klein, C. and Schlossmacher, M.G. (2006) The genetics of Parkinson disease: Implications for neurological care. Nat. Clin. Pract. Neurol.. 2, 136-146.
    • (2006) Nat. Clin. Pract. Neurol , vol.2 , pp. 136-146
    • Klein, C.1    Schlossmacher, M.G.2
  • 5
    • 17644365438 scopus 로고    scopus 로고
    • Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability
    • Beilina, A., Van Der Brug, M., Ahmad, R., Kesavapany, S., Miller, D.W., Petsko, G.A. and Cookson, M.R. (2005) Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability. Proc. Natl Acad. Sci. USA, 102 5703-5708.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 5703-5708
    • Beilina, A.1    Van Der Brug, M.2    Ahmad, R.3    Kesavapany, S.4    Miller, D.W.5    Petsko, G.A.6    Cookson, M.R.7
  • 7
    • 33750220194 scopus 로고    scopus 로고
    • C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1
    • Sim, C.H., Lio, D.S., Mok, S.S., Masters, C.L., Hill, A.F. Culvenor, J.G. and Cheng, H.C. (2006) C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1. Hum. Moll Genet., 15 3251-3262.
    • (2006) Hum. Moll Genet , vol.15 , pp. 3251-3262
    • Sim, C.H.1    Lio, D.S.2    Mok, S.S.3    Masters, C.L.4    Hill, A.F.5    Culvenor, J.G.6    Cheng, H.C.7
  • 8
    • 33746923419 scopus 로고    scopus 로고
    • Recessive Parkinson's disease
    • Kubo, S., Halton, N. and Mizuto, Y. (2006) Recessive Parkinson's disease. Mov. Disord., 21, 885-893.
    • (2006) Mov. Disord , vol.21 , pp. 885-893
    • Kubo, S.1    Halton, N.2    Mizuto, Y.3
  • 9
    • 33745602748 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
    • Park. J., Lee, S B., Lee, S., Kim, Y., Song, S., Kim, S., Bae, E., Kim, J., Shong, M., Kim, J.M, et al. (2006) Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature, 441, 1157-1161.
    • (2006) Nature , vol.441 , pp. 1157-1161
    • Park, J.1    Lee, S.B.2    Lee, S.3    Kim, Y.4    Song, S.5    Kim, S.6    Bae, E.7    Kim, J.8    Shong, M.9    Kim, J.M.10
  • 10
    • 33746080412 scopus 로고    scopus 로고
    • Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
    • Yang, Y., Gehrke, S., Imai, Y., Huang, Z., Ouyang, Y., Wang, J.W., Yang, L., BW, M.F., Vogel, H. and Lu, B. (2006) Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc. Natl Acad. Sci. USA, 103, 10793-10798.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 10793-10798
    • Yang, Y.1    Gehrke, S.2    Imai, Y.3    Huang, Z.4    Ouyang, Y.5    Wang, J.W.6    Yang, L.7    BW, M.F.8    Vogel, H.9    Lu, B.10
  • 11
    • 33745589773 scopus 로고    scopus 로고
    • (200) Drosophila pink1 is required for mitochondrial function and interacts genetically wit parkin
    • Clark, I.E., Dodson, M.W., Jiang, C., Can, J.H., Huh, J.R., Seol, J.H., Yoo,, S.J., Hay, B.A. and Guo, M. (200) Drosophila pink1 is required for mitochondrial function and interacts genetically wit parkin. Nature 441, 1162-1166.
    • Nature , vol.441 , pp. 1162-1166
    • Clark, I.E.1    Dodson, M.W.2    Jiang, C.3    Can, J.H.4    Huh, J.R.5    Seol, J.H.6    Yoo, S.J.7    Hay, B.A.8    Guo, M.9
  • 12
    • 27144469287 scopus 로고    scopus 로고
    • Small interfering RNA targeting the PINK1-induces apoptosis in dopaminergic cells SH-SY5Y
    • Deng, H., Jankovic, J., Guo, Y., Xie, W. and Le, W. (2005) Small interfering RNA targeting the PINK1-induces apoptosis in dopaminergic cells SH-SY5Y. Biochem. Biophys. Res. Commun., 337, 1133-1138.
    • (2005) Biochem. Biophys. Res. Commun , vol.337 , pp. 1133-1138
    • Deng, H.1    Jankovic, J.2    Guo, Y.3    Xie, W.4    Le, W.5
  • 13
    • 20444419344 scopus 로고    scopus 로고
    • Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis,and chemoresistance
    • MacKeigan, J.P., Murphy, L.O. and Blenis, J. (2005) Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis,and chemoresistance. Nat. Cell. Biol., 7, 591-600.
    • (2005) Nat. Cell. Biol , vol.7 , pp. 591-600
    • MacKeigan, J.P.1    Murphy, L.O.2    Blenis, J.3
  • 14
    • 26644440926 scopus 로고    scopus 로고
    • Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations
    • Petit, A., Kawarai, T., Paitel, E., Sanjo, N., Maj, M., Scheid, M., Chen, F., Gu, Y., Hasegawa, H., Salehi-Rad, S. et al. (2005) Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. J. Biol. Chem., 280, 34025-34032.
    • (2005) J. Biol. Chem , vol.280 , pp. 34025-34032
    • Petit, A.1    Kawarai, T.2    Paitel, E.3    Sanjo, N.4    Maj, M.5    Scheid, M.6    Chen, F.7    Gu, Y.8    Hasegawa, H.9    Salehi-Rad, S.10
  • 15
    • 34547127902 scopus 로고    scopus 로고
    • PINK1 Protects against Oxidative Stress by Phosphorylating Mitochondrial Chaperone TRAP1
    • Pridgeon, J.W., Olzmann, J.A., Chin, L.S. and Li, L. (2007) PINK1 Protects against Oxidative Stress by Phosphorylating Mitochondrial Chaperone TRAP1. PLoS Biol., 5, e172.
    • (2007) PLoS Biol , vol.5
    • Pridgeon, J.W.1    Olzmann, J.A.2    Chin, L.S.3    Li, L.4
  • 16
    • 33744760852 scopus 로고    scopus 로고
    • Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease
    • Tang, B., Xiong, H., Sun, P., Zhang, Y., Wang, D., Hu, Z., Zhu, Z., Ma, H., Pan, Q., Xia, J.H. et al. (2006) Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease. Hum. Mol. Genet., 15, 1916-1925.
    • (2006) Hum. Mol. Genet , vol.15 , pp. 1916-1925
    • Tang, B.1    Xiong, H.2    Sun, P.3    Zhang, Y.4    Wang, D.5    Hu, Z.6    Zhu, Z.7    Ma, H.8    Pan, Q.9    Xia, J.H.10
  • 19
    • 33846651282 scopus 로고    scopus 로고
    • Molecular chaperones and protein kinase quality control
    • Caplan, A.J., Mandal, A.K. and Theodoraki, M.A. (2007) Molecular chaperones and protein kinase quality control. Trends Cell. Biol., 17, 87-92.
    • (2007) Trends Cell. Biol , vol.17 , pp. 87-92
    • Caplan, A.J.1    Mandal, A.K.2    Theodoraki, M.A.3
  • 20
    • 0034718540 scopus 로고    scopus 로고
    • Modulation of Akt kinase activity by binding to Hsp90
    • Sato, S., Fujita, N. and Tsuruo, T. (2000) Modulation of Akt kinase activity by binding to Hsp90. Proc. Natl Acad. Sci. USA, 97, 10832-10837.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 10832-10837
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 21
    • 0036852712 scopus 로고    scopus 로고
    • Pharmacological prevention of Parkinson disease in Drosophila
    • Auluck, P.K. and Bonini, N.M. (2002) Pharmacological prevention of Parkinson disease in Drosophila. Nat. Med., 8, 1185-1186.
    • (2002) Nat. Med , vol.8 , pp. 1185-1186
    • Auluck, P.K.1    Bonini, N.M.2
  • 22
    • 0037428164 scopus 로고    scopus 로고
    • Molecular chaperones Nsp90 and Hsp70 deliver prcproteins to the mitochondrial. import receptor Tom70
    • Young, T.C., Hoogenraad, N.J. and Hartl, F.U. (2003) Molecular chaperones Nsp90 and Hsp70 deliver prcproteins to the mitochondrial. import receptor Tom70. Cell, 112, 41-50.
    • (2003) Cell , vol.112 , pp. 41-50
    • Young, T.C.1    Hoogenraad, N.J.2    Hartl, F.U.3
  • 23
    • 0037352446 scopus 로고    scopus 로고
    • Structural and functional analysis of the middle segment of hsp90: Implications for ATP hydrolysis and client protein and cochaperone interactions
    • Meyer, P., Prodromou, C., Hu, B., Vaughan, C., Roe, S.M., Panaretou, B., Piper, P. W. and Pearl, L,H. (2003) Structural and functional analysis of the middle segment of hsp90: Implications for ATP hydrolysis and client protein and cochaperone interactions. Mol Cell, 11, 647-658.
    • (2003) Mol Cell , vol.11 , pp. 647-658
    • Meyer, P.1    Prodromou, C.2    Hu, B.3    Vaughan, C.4    Roe, S.M.5    Panaretou, B.6    Piper, P.W.7    Pearl, L.H.8
  • 24
    • 33746381708 scopus 로고    scopus 로고
    • Geldanamycin, radicicol, and chimeric inhibitors of the Hsp90 N-terminal ATP binding site
    • Hadden, M.K. Lubbers, D.J. and Blagg, B.S. (2006) Geldanamycin, radicicol, and chimeric inhibitors of the Hsp90 N-terminal ATP binding site. Curr. Top. Med. Chem., 6, 1173-1182.
    • (2006) Curr. Top. Med. Chem , vol.6 , pp. 1173-1182
    • Hadden, M.K.1    Lubbers, D.J.2    Blagg, B.S.3
  • 25
    • 25444501262 scopus 로고    scopus 로고
    • A client-binding site of Cdc37
    • Terasawa, K. and Minami, Y. (2005) A client-binding site of Cdc37. FEBS J., 272, 4684-4690.
    • (2005) FEBS J , vol.272 , pp. 4684-4690
    • Terasawa, K.1    Minami, Y.2
  • 26
    • 0042527167 scopus 로고    scopus 로고
    • Cdc37 goes beyond Hsp90 and kinases
    • MacLean, M. and Picard, D. (2003) Cdc37 goes beyond Hsp90 and kinases. Cell Stress Chaperones, 8, 114-119.
    • (2003) Cell Stress Chaperones , vol.8 , pp. 114-119
    • MacLean, M.1    Picard, D.2
  • 27
    • 33244482539 scopus 로고    scopus 로고
    • Mutational analysis of the PINK1 gene in early-onset parkinsonism in: Europe and North Africa
    • Ibanez, P., Lesage, S., Lohmann, E., Thobois, S., De Michele, G., Borg, M., Agid, Y., Durr, A. and Brice, A. (2006) Mutational analysis of the PINK1 gene in early-onset parkinsonism in: Europe and North Africa. Brain, 129, 686-694.
    • (2006) Brain , vol.129 , pp. 686-694
    • Ibanez, P.1    Lesage, S.2    Lohmann, E.3    Thobois, S.4    De Michele, G.5    Borg, M.6    Agid, Y.7    Durr, A.8    Brice, A.9
  • 28
    • 33646434793 scopus 로고    scopus 로고
    • Parkin blushed by PINK1
    • Tan, J.M. and Dawson, T.M. (2006) Parkin blushed by PINK1. Neuron, 50, 521-529.
    • (2006) Neuron , vol.50 , pp. 521-529
    • Tan, J.M.1    Dawson, T.M.2
  • 30
    • 0032189258 scopus 로고    scopus 로고
    • Signal sequences: More than just greasy peptides
    • Martoglio, B. and Dobberstein, B. (1998) Signal sequences: More than just greasy peptides. Trends Cell. Biol., 8, 410-415.
    • (1998) Trends Cell. Biol , vol.8 , pp. 410-415
    • Martoglio, B.1    Dobberstein, B.2
  • 31
    • 33750445482 scopus 로고    scopus 로고
    • Mitochondrial fusion and fission in mammals
    • Chan, D.C. (2006) Mitochondrial fusion and fission in mammals. Annu. Rev. Cell. Dev. Biol., 22, 79-99.
    • (2006) Annu. Rev. Cell. Dev. Biol , vol.22 , pp. 79-99
    • Chan, D.C.1
  • 32
    • 4444327827 scopus 로고    scopus 로고
    • Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis
    • Jiang, H., Ren, Y., Zhao, J. and Feng, J. (2004) Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis. Hum. Mol. Genet., 13, 1745-1754,
    • (2004) Hum. Mol. Genet , vol.13 , pp. 1745-1754
    • Jiang, H.1    Ren, Y.2    Zhao, J.3    Feng, J.4
  • 33
    • 10644281090 scopus 로고    scopus 로고
    • Lentiviral vector delivery of parkin prevents dopaminergic degdneration in an alpha-synuclein rat model of Parkinson's disease
    • Lo Bianco, C., Schneider, B.L., Bauer, M., Sajadi, A., Brice, A., Iwatsubo, T. and Aebischer, P. (2004) Lentiviral vector delivery of parkin prevents dopaminergic degdneration in an alpha-synuclein rat model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 101 17510-17515.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 17510-17515
    • Lo Bianco, C.1    Schneider, B.L.2    Bauer, M.3    Sajadi, A.4    Brice, A.5    Iwatsubo, T.6    Aebischer, P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.