Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons

Journal of Neuroscience

Volumn 34, Issue 43, 2014, Pages 14304-14317

  Berthet, Amandine ^a   Margolis, Elyssa B ^b   Zhang, Jue ^a   Hsieh, Ivy ^e   Zhang, Jiasheng ^e   Hnasko, Thomas S ^c   Ahmad, Jawad ^a   Edwards, Robert H ^b   Sesaki, Hiromi ^d   Huang, Eric J ^b,e   Nakamura, Ken ^a,b  

^a GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Axon; Drp1; Mitochondria; Neurodegeneration; Parkinson s disease

Indexed keywords

ALPHA SYNUCLEIN; BRAIN MONOAMINE; CALBINDIN; DYNAMIN; DNM1L PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MOTILITY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ELECTRON MICROSCOPY; ELECTROPHYSIOLOGY; FEMALE; GENE DELETION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOLOGY; HYPERPOLARIZATION; IMMUNOFLUORESCENCE; LOCOMOTION; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL FISSION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; WHOLE CELL PATCH CLAMP; ANIMAL; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; MEMBRANE POTENTIAL; MESENCEPHALON; METABOLISM; MITOCHONDRION; NERVE FIBER; ORGAN CULTURE TECHNIQUE; PATHOLOGY; PHYSIOLOGY;

ANIMALS; AXONS; DOPAMINERGIC NEURONS; DYNAMINS; FEMALE; MALE; MEMBRANE POTENTIALS; MESENCEPHALON; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; ORGAN CULTURE TECHNIQUES;

EID: 84908079648     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0930-14.2014     Document Type: Article

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