Tetrahydrobiopterin Scavenges Superoxide in Dopaminergic Neurons

Journal of Biological Chemistry

Volumn 276, Issue 37, 2001, Pages 34402-34407

  Nakamura, Ken ^a   Bindokas, Vytautas P ^c   Kowlessur, Devanand ^a   Elas, Martyna ^a   Milstien, Sheldon ^b   Marks, Jeremy D ^a   Halpern, Howard J ^a   Kang, Un Jung ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c National Institute of Mental Health ^*

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; DISEASES; NEUROLOGY; NITROGEN OXIDES; OXIDATION; PHYSIOLOGY; PROTEINS;

NEURONS;

PATHOLOGY;

ANTIMYCIN A1; CATECHOLAMINE; DOPAMINE; GLUTATHIONE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; ROTENONE; SCAVENGER; SUPEROXIDE; TETRAHYDROBIOPTERIN; 5,6,7,8-TETRAHYDROBIOPTERIN; BIOPTERIN; DRUG DERIVATIVE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; DOPAMINERGIC NERVE CELL; FIBROBLAST; IMMUNOHISTOCHEMISTRY; MESENCEPHALON; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; ANIMAL; FEMALE; METABOLISM; MITOCHONDRION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALIA;

ANIMALS; BIOPTERIN; DOPAMINE; FEMALE; FIBROBLASTS; FREE RADICAL SCAVENGERS; MESENCEPHALON; MITOCHONDRIA; NITRIC OXIDE; PARKINSON DISEASE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 0035860682     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103766200     Document Type: Article

References (55)

1. Sian, J., Dexter, D. T., Lees, A. J., Daniel, S., Agid, Y., Javoy-Agid, F., Jenner, P., and Marsden, C. D. (1994) Ann. Neurol. 36, 348-355
2. Yoritaka, A., Hattori, N., Uchida, K., Tanaka, M., Stadtman, E. R., and Mizuno, Y. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 2696-2701
3. Alam, Z. I., Daniel, S. E., Lees, A. J., Marsden, D. C., Jenner, P., and Halliwell, B. (1997) J. Neurochem. 69, 1326-1329
4. Alam, Z. I., Jenner, A., Daniel, S. E., Lees, A. J., Cairns, N., Marsden, C. D., Jenner, P., and Halliwell, B. (1997) J. Neurochem. 69, 1196-1203
5. Jenner, P., and Olanow, C. W. (1998) Ann. Neurol. 44, S72-S84
6. Dexter, D. T., Sian, J., Rose, S., Hindmarsh, J. G., Mann, V. M., Cooper, J. M., Wells, F. R., Daniel, S. E., Lees, A. J., Schapira, A. H. V., Jenner, P., and Marsden, C. D. (1994) Ann. Neurol. 35, 38-44
7. Schapira, A. H. V., Mann, V. M., Cooper, J. M., Krige, D., Jenner, P. J., and Marsden, C. D. (1992) Ann. Neurol. 32, S116-S124
8. Mann, V. M., Cooper, J. M., Krige, D., Daniel, S. E., Schapira, A. H. V., and Marsden, C. D. (1992) Brain 115, 333-342
9. Kwong, L. K., and Sohal, R. S. (1998) Arch. Biochem. Biophys. 350, 118-126
10. Turrens, J. F., and Boveris, A. (1980) Biochem. J. 191, 421-427
11. Toffa, S., Kunikowska, G. M., Zeng, B. Y., Jenner, P., and Marsden, C. D. (1997) J. Neural. Transm. 104, 67-75
12. Pileblad, E., Magnusson, T., and Fornstedt, B. (1989) J. Neurochem. 52, 978-980
13. Wullner, U., Loschmann, P., Schulz, J., Schmid, A., Dringen, R., Eblen, F., Turski, L., and Klockgether, T. (1996) Neuroreport 7, 921-923
14. Nakamura, K., Wang, W., and Kang, U. J. (1997) J. Neurochem. 69, 1850-1858
15. Nakamura, K., Won, L., Heller, A., and Kang, U. J. (2000) Brain Res. 873, 203-211
16. Wever, R. M. F., van Dam, T., nan Rijn, H. J. M., de Groot, F., and Rabelink, T. J. (1997) Biochem. Biophys. Res. Commun. 237, 340-344
17. Kojima, S., Icho, T., Kajiwara, Y., and Kubota, K. (1992) FEBS Lett. 304, 163-166
18. Stroes, E., Hijmering, M., Zandvoort, M., Wever, R., Rabelink, T. J., and Faassen, E. E. (1998) FEBS Lett. 438, 161-164
19. Vasquez-Vivar, J., Kalyanaraman, B., Martasek, P., Hogg, N., Masters, B. S. S., Karoui, H., Tordo, P., and Pritchard, K. A., Jr. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 9220-9225
20. Heales, S. J. R., Blair, J. A., Meinschad, C., and Ziegler, I. (1988) Cell Biochem. Funct. 6, 191-195
21. Koshimura, K., Murakami, Y., Tanaka, J., and Kato, Y. (1998) J. Neurosci. Res. 54, 664-672
22. Shen, R., and Zhang, Y. (1993) Adv. Exp. Med. Biol. 338, 351-354
23. Ishii, M., Shimizu, S., Momose, K., and Yamamoto, T. (1999) J. Cardiovasc. Pharmacol. 33, 295-300
24. Bindokas, V., Jordan, J., Lee, C., and Miller, R. (1996) J. Neurosci. 16, 1324-1336
25. Gallop, P. M., Paz, M. A., Henson, E., and Latt, S. A. (1984) BioTechniques 2, 32-36
26. Carter, W. O., Narayanan, P. K., and Robinson, J. P. (1994) J. Leukoc. Biol. 55, 253-258
27. Ischiropoulos, H., Gow, A., Thom, S. R., Kooy, N. W., Royall, J. A., and Crow, J. P. (1999) Methods Enzymol. 301, 367-373
28. Reiter, C. D., Teng, R. J., and Beckman, J. S. (2000) J. Biol. Chem. 275, 32460-32466
29. Roubaud, V., Sankarapandi, S., Kuppusamy, P., Tordo, P., and Zweier, J. L. (1997) Anal. Biochem. 247, 404-411
30. Smith, G. K., Duch, D. S., Edelstein, M. P., and Bigham, E. C. (1992) J. Biol. Chem. 267, 5599-5607
31. Nakamura, K., Wright, D. A., Wiatr, T., Kowlessur, D., Milstien, S., Lei, X. G., and Kang, U. J. (2000) J. Neurochem. 74, 2305-2315
32. Bencsics, C., Wachtel, S. R., Milstien, S., Hatakeyama, K., Becker, J. B., and Kang, U. J. (1996) J. Neurosci. 16, 4449-4456
33. Pou, S., Pou, W. S., Bredt, D. S., Snyder, S. H., and Rosen, G. M. (1992) J. Biol. Chem. 267, 24173-24176
34. Herrero, A., and Barja, G. (1997) J. Bioenerg. Biomembr. 29, 241-249
35. Pitkanen, S., and Robinson, B. H. (1996) J. Clin. Invest. 98, 345-351
36. Hensley, K., Pye, Q. N., Maidt, M. L., Stewart, C. A., Robinson, K. A., Jaffrey, F., and Floyd, R. A. (1998) J. Neurochem. 71, 2549-2557
37. Budd, S. L., Castilho, R. F., and Nicholls, D. G. (1997) FEBS Lett. 415, 21-24
38. Lokesh, B. R., and Cunningham, M. L. (1986) Toxicol. Lett. 34, 75-84
39. Haavik, J., Almas, B., and Flatmark, T. (1997) J. Neurochem. 68, 328-332
40. Kojima, S., Ona, S., Iizuka, I., Arai, T., Mori, H., and Kubota, K. (1995) Free Radic. Res. 23, 419-430
41. Sawada, H., Kawamura, T., Shimohama, S., Akaike, A., and Kimura, J. (1996) J. Neurosci. Res. 43, 503-510
42. Sawada, H., Shimohama, S., Kawamura, T., Akaike, A., Kitamura, Y., Taniguchi, T., and Kimura, J. (1996) J. Neurosci. Res. 46, 509-518
43. Gonzalez-Zuleta, M., Ensz, L. M., Mukhina, G., Lebovitz, R. M., Zwacka, R. M., Enmgelhardt, J. F., Oberley, L. W., Dawson, V. L., and Dawson, T. M. (1998) J. Neurosci. 18, 2040-2055
44. Skulachev, V. P. (1996) Q. Rev. Biophys. 29, 169-202
45. Turrens, J. F. (1997) Biosci. Rep. 17, 3-8
46. Mayer, B., and Werner, E. R. (1995) Naunyn-Schmiedeberg's Arch. Pharmacol. 351, 453-463
47. Schmidt, H. H., Hofmann, H., Schindler, U., Shutenko, Z. S., Cunningham, D. D., and Feelisch, M. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 14492-14497
48. Xia, Y., Tsai, A. L., Berka, V., and Zweier, J. L. (1998) J. Biol. Chem. 273, 25804-25808
49. Vasquez-Vivar, J., Hogg, N., Martasek, P., Karoui, H., Pritchard, K. A., Jr., and Kalyanaraman, B. (1999) J. Biol. Chem. 274, 26736-26742
50. Levine, R. A., Miller, L. P., and Lovenberg, W. (1981) Science 214, 919-921
51. Lentz, S. I., and Kapatos, G. (1996) Neurochem. Int. 28, 569-582
52. Hirayama, K., and Kapatos, G. (1998) J. Neurochem. 70, 164-170
53. Yoshida, Y., Eda, S., and Masada, M. (2000) Brain Dev. 22, Suppl. 1, 45-49
54. Furukawa, Y., and Kish, S. J. (1998) Neurology 51, 632-634
55. Chen, E. Y., Kallwitz, E., Leff, S. E., Cochran, E. J., Mufson, E. J., Kordower, J. H., and Mandel, R. J. (2000) J. Comp. Neurol. 426, 534-548