-
1
-
-
33646151866
-
LRRK2 in Parkinson's disease: protein domains and functional insights
-
Mata, I.F., Wedemeyer, W.J., Farrer, M.J., Taylor, J.P. and Gallo, K.A. (2006) LRRK2 in Parkinson's disease: protein domains and functional insights. Trends Neurosci., 29, 286-293.
-
(2006)
Trends Neurosci
, vol.29
, pp. 286-293
-
-
Mata, I.F.1
Wedemeyer, W.J.2
Farrer, M.J.3
Taylor, J.P.4
Gallo, K.A.5
-
2
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
-
Zimprich, A., Biskup, S., Leitner, P., Lichtner, P., Farrer, M., Lincoln, S., Kachergus, J., Hulihan, M., Uitti, R.J., Calne, D.B. et al. (2004) Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron, 44, 601-607.
-
(2004)
Neuron
, vol.44
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
Lichtner, P.4
Farrer, M.5
Lincoln, S.6
Kachergus, J.7
Hulihan, M.8
Uitti, R.J.9
Calne, D.B.10
-
3
-
-
8844266996
-
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
-
Paisan-Ruiz, C., Jain, S., Evans, E.W., Gilks, W.P., Simon, J., van der Brug, M., Lopez de Munain, A., Aparicio, S., Gil, A.M., Khan, N. et al. (2004) Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron, 44, 595-600.
-
(2004)
Neuron
, vol.44
, pp. 595-600
-
-
Paisan-Ruiz, C.1
Jain, S.2
Evans, E.W.3
Gilks, W.P.4
Simon, J.5
van der Brug, M.6
Lopez de Munain, A.7
Aparicio, S.8
Gil, A.M.9
Khan, N.10
-
4
-
-
63149090431
-
Parkinson's disease: from monogenic forms to genetic susceptibility factors
-
Lesage, S. and Brice, A. (2009) Parkinson's disease: from monogenic forms to genetic susceptibility factors. Hum. Mol. Genet., 18, R48-R59.
-
(2009)
Hum. Mol. Genet.
, vol.18
-
-
Lesage, S.1
Brice, A.2
-
5
-
-
55849122639
-
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
-
Henchcliffe, C. and Beal, M.F. (2008) Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nat. Clin. Pract. Neurol., 4, 600-609.
-
(2008)
Nat. Clin. Pract. Neurol.
, vol.4
, pp. 600-609
-
-
Henchcliffe, C.1
Beal, M.F.2
-
6
-
-
33745274726
-
Mitochondria: dynamic organelles in disease, aging, and development
-
Chan, D.C. (2006) Mitochondria: dynamic organelles in disease, aging, and development. Cell, 125, 1241-1252.
-
(2006)
Cell
, vol.125
, pp. 1241-1252
-
-
Chan, D.C.1
-
7
-
-
45749117188
-
Mitochondrial fragmentation in neurodegeneration
-
Knott, A.B., Perkins, G., Schwarzenbacher, R. and Bossy-Wetzel, E. (2008) Mitochondrial fragmentation in neurodegeneration. Nat. Rev. Neurosci., 9, 505-518.
-
(2008)
Nat. Rev. Neurosci.
, vol.9
, pp. 505-518
-
-
Knott, A.B.1
Perkins, G.2
Schwarzenbacher, R.3
Bossy-Wetzel, E.4
-
8
-
-
71849083948
-
Abnormal mitochondrial dynamics and neurodegenerative diseases
-
Su, B., Wang, X., Zheng, L., Perry, G., Smith, M.A. and Zhu, X. (2010) Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochim. Biophys. Acta., 1802, 135-142.
-
(2010)
Biochim. Biophys. Acta.
, vol.1802
, pp. 135-142
-
-
Su, B.1
Wang, X.2
Zheng, L.3
Perry, G.4
Smith, M.A.5
Zhu, X.6
-
9
-
-
77956522541
-
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
-
Irrcher, I., Aleyasin, H., Seifert, E.L., Hewitt, S.J., Chhabra, S., Phillips, M., Lutz, A.K., Rousseaux, M.W., Bevilacqua, L., Jahani-Asl, A. et al. (2010) Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Hum. Mol. Genet., 19, 3734-3746.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
Phillips, M.6
Lutz, A.K.7
Rousseaux, M.W.8
Bevilacqua, L.9
Jahani-Asl, A.10
-
10
-
-
66349123690
-
Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1
-
Sandebring, A., Thomas, K.J., Beilina, A., van der Brug, M., Cleland, M.M., Ahmad, R., Miller, D.W., Zambrano, I., Cowburn, R.F., Behbahani, H. et al. (2009) Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1. PLoS ONE, 4, e5701.
-
(2009)
PLoS ONE
, vol.4
-
-
Sandebring, A.1
Thomas, K.J.2
Beilina, A.3
van der Brug, M.4
Cleland, M.M.5
Ahmad, R.6
Miller, D.W.7
Zambrano, I.8
Cowburn, R.F.9
Behbahani, H.10
-
11
-
-
44349195101
-
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
-
Yang, Y., Ouyang, Y., Yang, L., Beal, M.F., McQuibban, A., Vogel, H. and Lu, B. (2008) Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery. Proc. Natl Acad. Sci. USA, 105, 7070-7075.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 7070-7075
-
-
Yang, Y.1
Ouyang, Y.2
Yang, L.3
Beal, M.F.4
McQuibban, A.5
Vogel, H.6
Lu, B.7
-
12
-
-
55749090654
-
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
-
Deng, H., Dodson, M.W., Huang, H. and Guo, M. (2008) The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proc. Natl Acad. Sci. USA, 105, 14503-14508.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 14503-14508
-
-
Deng, H.1
Dodson, M.W.2
Huang, H.3
Guo, M.4
-
13
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole, A.C., Thomas, R.E., Andrews, L.A., McBride, H.M., Whitworth, A.J. and Pallanck, L.J. (2008) The PINK1/Parkin pathway regulates mitochondrial morphology. Proc. Natl Acad. Sci. USA, 105, 1638-1643.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
14
-
-
77958450202
-
Inhibition of mitochondrial fusion by alpha-synuclein is rescued by PINK1, Parkin and DJ-1
-
Kamp, F., Exner, N., Lutz, A.K., Wender, N., Hegermann, J., Brunner, B., Nuscher, B., Bartels, T., Giese, A., Beyer, K. et al. (2010) Inhibition of mitochondrial fusion by alpha-synuclein is rescued by PINK1, Parkin and DJ-1. EMBO J., 29, 3571-3589.
-
(2010)
EMBO J
, vol.29
, pp. 3571-3589
-
-
Kamp, F.1
Exner, N.2
Lutz, A.K.3
Wender, N.4
Hegermann, J.5
Brunner, B.6
Nuscher, B.7
Bartels, T.8
Giese, A.9
Beyer, K.10
-
15
-
-
36049038504
-
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin
-
Exner, N., Treske, B., Paquet, D., Holmstrom, K., Schiesling, C., Gispert, S., Carballo-Carbajal, I., Berg, D., Hoepken, H.H., Gasser, T. et al. (2007) Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin. J. Neurosci., 27, 12413-12418.
-
(2007)
J. Neurosci.
, vol.27
, pp. 12413-12418
-
-
Exner, N.1
Treske, B.2
Paquet, D.3
Holmstrom, K.4
Schiesling, C.5
Gispert, S.6
Carballo-Carbajal, I.7
Berg, D.8
Hoepken, H.H.9
Gasser, T.10
-
16
-
-
80052794422
-
DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease
-
Wang, X., Su, B., Liu, W., He, X., Gao, Y., Castellani, R.J., Perry, G., Smith, M.A. and Zhu, X. (2011) DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell, 10, 807-823.
-
(2011)
Aging Cell
, vol.10
, pp. 807-823
-
-
Wang, X.1
Su, B.2
Liu, W.3
He, X.4
Gao, Y.5
Castellani, R.J.6
Perry, G.7
Smith, M.A.8
Zhu, X.9
-
17
-
-
33845298032
-
Localization of LRRK2 to membranous and vesicular structures in mammalian brain
-
Biskup, S., Moore, D.J., Celsi, F., Higashi, S., West, A.B., Andrabi, S.A., Kurkinen, K., Yu, S.W., Savitt, J.M., Waldvogel, H.J. et al. (2006) Localization of LRRK2 to membranous and vesicular structures in mammalian brain. Ann. Neurol., 60, 557-569.
-
(2006)
Ann. Neurol.
, vol.60
, pp. 557-569
-
-
Biskup, S.1
Moore, D.J.2
Celsi, F.3
Higashi, S.4
West, A.B.5
Andrabi, S.A.6
Kurkinen, K.7
Yu, S.W.8
Savitt, J.M.9
Waldvogel, H.J.10
-
18
-
-
28044460070
-
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
-
West, A.B., Moore, D.J., Biskup, S., Bugayenko, A., Smith, W.W., Ross, C.A., Dawson, V.L. and Dawson, T.M. (2005) Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proc. Natl Acad. Sci. USA, 102, 16842-16847.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 16842-16847
-
-
West, A.B.1
Moore, D.J.2
Biskup, S.3
Bugayenko, A.4
Smith, W.W.5
Ross, C.A.6
Dawson, V.L.7
Dawson, T.M.8
-
19
-
-
67651171368
-
LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans
-
Saha, S., Guillily, M.D., Ferree, A., Lanceta, J., Chan, D., Ghosh, J., Hsu, C.H., Segal, L., Raghavan, K., Matsumoto, K. et al. (2009) LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans. J. Neurosci., 29, 9210-9218.
-
(2009)
J. Neurosci.
, vol.29
, pp. 9210-9218
-
-
Saha, S.1
Guillily, M.D.2
Ferree, A.3
Lanceta, J.4
Chan, D.5
Ghosh, J.6
Hsu, C.H.7
Segal, L.8
Raghavan, K.9
Matsumoto, K.10
-
20
-
-
70349103837
-
Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila
-
Ng, C.H., Mok, S.Z., Koh, C., Ouyang, X., Fivaz, M.L., Tan, E.K., Dawson, V.L., Dawson, T.M., Yu, F. and Lim, K.L. (2009) Parkin protects against LRRK2 G2019S mutant-induced dopaminergic neurodegeneration in Drosophila. J. Neurosci., 29, 11257-11262.
-
(2009)
J. Neurosci.
, vol.29
, pp. 11257-11262
-
-
Ng, C.H.1
Mok, S.Z.2
Koh, C.3
Ouyang, X.4
Fivaz, M.L.5
Tan, E.K.6
Dawson, V.L.7
Dawson, T.M.8
Yu, F.9
Lim, K.L.10
-
21
-
-
70350683754
-
Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease
-
Venderova, K., Kabbach, G., Abdel-Messih, E., Zhang, Y., Parks, R.J., Imai, Y., Gehrke, S., Ngsee, J., Lavoie, M.J., Slack, R.S. et al. (2009) Leucine-rich repeat kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease. Hum. Mol. Genet., 18, 4390-4404.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 4390-4404
-
-
Venderova, K.1
Kabbach, G.2
Abdel-Messih, E.3
Zhang, Y.4
Parks, R.J.5
Imai, Y.6
Gehrke, S.7
Ngsee, J.8
Lavoie, M.J.9
Slack, R.S.10
-
22
-
-
67650233672
-
Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth
-
Samann, J., Hegermann, J., von Gromoff, E., Eimer, S., Baumeister, R. and Schmidt, E. (2009) Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth. J. Biol. Chem., 284, 16482-16491.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 16482-16491
-
-
Samann, J.1
Hegermann, J.2
von Gromoff, E.3
Eimer, S.4
Baumeister, R.5
Schmidt, E.6
-
23
-
-
78650025189
-
Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2
-
Mortiboys, H., Johansen, K.K., Aasly, J.O. and Bandmann, O. (2010) Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2. Neurology, 75, 2017-2020.
-
(2010)
Neurology
, vol.75
, pp. 2017-2020
-
-
Mortiboys, H.1
Johansen, K.K.2
Aasly, J.O.3
Bandmann, O.4
-
24
-
-
33846562487
-
Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity
-
West, A.B., Moore, D.J., Choi, C., Andrabi, S.A., Li, X., Dikeman, D., Biskup, S., Zhang, Z., Lim, K.L., Dawson, V.L. et al. (2007) Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity. Hum. Mol. Genet., 16, 223-232.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 223-232
-
-
West, A.B.1
Moore, D.J.2
Choi, C.3
Andrabi, S.A.4
Li, X.5
Dikeman, D.6
Biskup, S.7
Zhang, Z.8
Lim, K.L.9
Dawson, V.L.10
-
25
-
-
80053152848
-
Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models
-
Liu, Z., Hamamichi, S., Dae Lee, B., Yang, D., Ray, A., Caldwell, G.A., Caldwell, K.A., Dawson, T.M., Smith, W.W. and Dawson, V.L. (2011) Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models. Hum. Mol. Genet., 20, 3933-3942.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 3933-3942
-
-
Liu, Z.1
Hamamichi, S.2
Dae Lee, B.3
Yang, D.4
Ray, A.5
Caldwell, G.A.6
Caldwell, K.A.7
Dawson, T.M.8
Smith, W.W.9
Dawson, V.L.10
-
26
-
-
33748993710
-
Kinase activity of mutant LRRK2 mediates neuronal toxicity
-
Smith, W.W., Pei, Z., Jiang, H., Dawson, V.L., Dawson, T.M. and Ross, C.A. (2006) Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nat. Neurosci., 9, 1231-1233.
-
(2006)
Nat. Neurosci.
, vol.9
, pp. 1231-1233
-
-
Smith, W.W.1
Pei, Z.2
Jiang, H.3
Dawson, V.L.4
Dawson, T.M.5
Ross, C.A.6
-
27
-
-
58049218922
-
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
-
Wang, X., Su, B., Siedlak, S.L., Moreira, P.I., Fujioka, H., Wang, Y., Casadesus, G. and Zhu, X. (2008) Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc. Natl Acad. Sci. USA, 105, 19318-19323.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 19318-19323
-
-
Wang, X.1
Su, B.2
Siedlak, S.L.3
Moreira, P.I.4
Fujioka, H.5
Wang, Y.6
Casadesus, G.7
Zhu, X.8
-
28
-
-
0032559599
-
A novel dynamin-like protein associates with cytoplasmic vesicles and tubules of the endoplasmic reticulum in mammalian cells
-
Yoon, Y., Pitts, K.R., Dahan, S. and McNiven, M.A. (1998) A novel dynamin-like protein associates with cytoplasmic vesicles and tubules of the endoplasmic reticulum in mammalian cells. J. Cell Biol., 140, 779-793.
-
(1998)
J. Cell Biol.
, vol.140
, pp. 779-793
-
-
Yoon, Y.1
Pitts, K.R.2
Dahan, S.3
McNiven, M.A.4
-
29
-
-
67650732998
-
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
-
Wang, X., Su, B., Lee, H.G., Li, X., Perry, G., Smith, M.A. and Zhu, X. (2009) Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J. Neurosci., 29, 9090-9103.
-
(2009)
J. Neurosci.
, vol.29
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.G.3
Li, X.4
Perry, G.5
Smith, M.A.6
Zhu, X.7
-
30
-
-
0038783254
-
Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells
-
Santel, A., Frank, S., Gaume, B., Herrler, M., Youle, R.J. and Fuller, M.T. (2003) Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells. J. Cell Sci., 116, 2763-2774.
-
(2003)
J. Cell Sci.
, vol.116
, pp. 2763-2774
-
-
Santel, A.1
Frank, S.2
Gaume, B.3
Herrler, M.4
Youle, R.J.5
Fuller, M.T.6
-
31
-
-
0037424239
-
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
-
Olichon, A., Baricault, L., Gas, N., Guillou, E., Valette, A., Belenguer, P. and Lenaers, G. (2003) Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J. Biol. Chem., 278, 7743-7746.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7743-7746
-
-
Olichon, A.1
Baricault, L.2
Gas, N.3
Guillou, E.4
Valette, A.5
Belenguer, P.6
Lenaers, G.7
-
32
-
-
0037089084
-
Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo
-
Rojo, M., Legros, F., Chateau, D. and Lombes, A. (2002) Membrane topology and mitochondrial targeting of mitofusins, ubiquitous mammalian homologs of the transmembrane GTPase Fzo. J. Cell Sci., 115, 1663-1674.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 1663-1674
-
-
Rojo, M.1
Legros, F.2
Chateau, D.3
Lombes, A.4
-
33
-
-
79952443408
-
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity
-
Song, W., Chen, J., Petrilli, A., Liot, G., Klinglmayr, E., Zhou, Y., Poquiz, P., Tjong, J., Pouladi, M.A., Hayden, M.R. et al. (9999) Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nat. Med., 17, 377-382.
-
(1999)
Nat. Med.
, vol.17
, pp. 377-382
-
-
Song, W.1
Chen, J.2
Petrilli, A.3
Liot, G.4
Klinglmayr, E.5
Zhou, Y.6
Poquiz, P.7
Tjong, J.8
Pouladi, M.A.9
Hayden, M.R.10
-
34
-
-
79958721260
-
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
-
Manczak, M., Calkins, M.J. and Reddy, P.H. (2011) Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage. Hum. Mol. Genet., 20, 2495-2509.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2495-2509
-
-
Manczak, M.1
Calkins, M.J.2
Reddy, P.H.3
-
35
-
-
79952585486
-
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage
-
Shirendeb, U., Reddy, A.P., Manczak, M., Calkins, M.J., Mao, P., Tagle, D.A. and Reddy, P.H. (2011) Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage. Hum. Mol. Genet., 20, 1438-1455.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 1438-1455
-
-
Shirendeb, U.1
Reddy, A.P.2
Manczak, M.3
Calkins, M.J.4
Mao, P.5
Tagle, D.A.6
Reddy, P.H.7
-
36
-
-
78649389313
-
The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
-
Cookson, M.R. (2010) The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease. Nat. Rev. Neurosci., 11, 791-797.
-
(2010)
Nat. Rev. Neurosci.
, vol.11
, pp. 791-797
-
-
Cookson, M.R.1
-
37
-
-
77955298543
-
Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1
-
Chang, C.R. and Blackstone, C. (2010) Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1. Ann. N. Y. Acad. Sci., 1201, 34-39.
-
(2010)
Ann. N. Y. Acad. Sci.
, vol.1201
, pp. 34-39
-
-
Chang, C.R.1
Blackstone, C.2
-
38
-
-
70449732284
-
The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites
-
Greggio, E., Taymans, J.M., Zhen, E.Y., Ryder, J., Vancraenenbroeck, R., Beilina, A., Sun, P., Deng, J., Jaffe, H., Baekelandt, V. et al. (2009) The Parkinson's disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites. Biochem. Biophys. Res. Commun., 389, 449-454.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.389
, pp. 449-454
-
-
Greggio, E.1
Taymans, J.M.2
Zhen, E.Y.3
Ryder, J.4
Vancraenenbroeck, R.5
Beilina, A.6
Sun, P.7
Deng, J.8
Jaffe, H.9
Baekelandt, V.10
-
39
-
-
57749100375
-
Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts
-
Mortiboys, H., Thomas, K.J., Koopman, W.J., Klaffke, S., Abou-Sleiman, P., Olpin, S., Wood, N.W., Willems, P.H., Smeitink, J.A., Cookson, M.R. et al. (2008) Mitochondrial function and morphology are impaired in parkin-mutant fibroblasts. Ann. Neurol., 64, 555-565.
-
(2008)
Ann. Neurol.
, vol.64
, pp. 555-565
-
-
Mortiboys, H.1
Thomas, K.J.2
Koopman, W.J.3
Klaffke, S.4
Abou-Sleiman, P.5
Olpin, S.6
Wood, N.W.7
Willems, P.H.8
Smeitink, J.A.9
Cookson, M.R.10
-
40
-
-
69249096578
-
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation
-
Lutz, A.K., Exner, N., Fett, M.E., Schlehe, J.S., Kloos, K., Lammermann, K., Brunner, B., Kurz-Drexler, A., Vogel, F., Reichert, A.S. et al. (2009) Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation. J. Biol. Chem., 284, 22938-22951.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 22938-22951
-
-
Lutz, A.K.1
Exner, N.2
Fett, M.E.3
Schlehe, J.S.4
Kloos, K.5
Lammermann, K.6
Brunner, B.7
Kurz-Drexler, A.8
Vogel, F.9
Reichert, A.S.10
-
41
-
-
48749085779
-
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients
-
Wang, X., Su, B., Fujioka, H. and Zhu, X. (2008) Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients. Am. J. Pathol., 173, 470-482.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 470-482
-
-
Wang, X.1
Su, B.2
Fujioka, H.3
Zhu, X.4
-
42
-
-
22544451586
-
Disruption of fusion results in mitochondrial heterogeneity and dysfunction
-
Chen, H., Chomyn, A. and Chan, D.C. (2005) Disruption of fusion results in mitochondrial heterogeneity and dysfunction. J. Biol. Chem., 280, 26185-26192.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 26185-26192
-
-
Chen, H.1
Chomyn, A.2
Chan, D.C.3
-
43
-
-
0037455575
-
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
-
Chen, H., Detmer, S.A., Ewald, A.J., Griffin, E.E., Fraser, S.E. and Chan, D.C. (2003) Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J. Cell Biol., 160, 189-200.
-
(2003)
J. Cell Biol.
, vol.160
, pp. 189-200
-
-
Chen, H.1
Detmer, S.A.2
Ewald, A.J.3
Griffin, E.E.4
Fraser, S.E.5
Chan, D.C.6
-
44
-
-
58849101755
-
Assessment of cell viability in primary neuronal cultures
-
Chapter 7, Unit 7.18
-
Aras, M.A., Hartnett, K.A. and Aizenman, E. (2008) Assessment of cell viability in primary neuronal cultures. Curr. Protoc. Neurosci., Chapter 7, Unit 7.18.
-
(2008)
Curr. Protoc. Neurosci.
-
-
Aras, M.A.1
Hartnett, K.A.2
Aizenman, E.3
-
45
-
-
56249140087
-
Computer-assisted live cell analysis of mitochondrial membrane potential, morphology and calcium handling
-
Koopman, W.J., Distelmaier, F., Esseling, J.J., Smeitink, J.A. and Willems, P.H. (2008) Computer-assisted live cell analysis of mitochondrial membrane potential, morphology and calcium handling. Methods, 46, 304-311.
-
(2008)
Methods
, vol.46
, pp. 304-311
-
-
Koopman, W.J.1
Distelmaier, F.2
Esseling, J.J.3
Smeitink, J.A.4
Willems, P.H.5
|