-
1
-
-
84880638696
-
From rags to riches—the history of the endoplasmic reticulum
-
23500901
-
Schuldiner M, Schwappach B. From rags to riches—the history of the endoplasmic reticulum. Biochim Biophys Acta 2013; 1833:2389-91; PMID:23500901; http://dx.doi.org/10.1016/j.bbamcr.2013.03.005
-
(2013)
Biochim Biophys Acta
, vol.1833
, pp. 2389-2391
-
-
Schuldiner, M.1
Schwappach, B.2
-
2
-
-
0000628018
-
Liver microsomes; an integrated morphological and biochemical study
-
13319380
-
Palade GE, Siekevitz P. Liver microsomes; an integrated morphological and biochemical study. J Biophys Biochem Cytol 1956; 2:171-200; PMID:13319380; http://dx.doi.org/10.1083/jcb.2.2.171
-
(1956)
J Biophys Biochem Cytol
, vol.2
, pp. 171-200
-
-
Palade, G.E.1
Siekevitz, P.2
-
3
-
-
0010538176
-
A study in microtomy for electron microscopy
-
13124776
-
Porter KR, Blum J. A study in microtomy for electron microscopy. Anat Rec 1953; 117:685-710; PMID:13124776; http://dx.doi.org/10.1002/ar.1091170403
-
(1953)
Anat Rec
, vol.117
, pp. 685-710
-
-
Porter, K.R.1
Blum, J.2
-
4
-
-
0000628017
-
Pancreatic microsomes; an integrated morphological and biochemical study
-
13398437
-
Palade GE, Siekevitz P. Pancreatic microsomes; an integrated morphological and biochemical study. J Biophys Biochem Cytol 1956; 2:671-90; PMID:13398437; http://dx.doi.org/10.1083/jcb.2.6.671
-
(1956)
J Biophys Biochem Cytol
, vol.2
, pp. 671-690
-
-
Palade, G.E.1
Siekevitz, P.2
-
5
-
-
72949126637
-
The calcium pump of the “relaxing granules” of muscle and its dependence on ATP-splitting
-
13712164,; PMID
-
Hasselbach W, Makinose M. [The calcium pump of the “relaxing granules” of muscle and its dependence on ATP-splitting]. Biochem Z 1961; 333:518-28; PMID:13712164
-
(1961)
Biochem Z
, vol.333
, pp. 518-528
-
-
Hasselbach, W.1
Makinose, M.2
-
6
-
-
84968965880
-
Adenosine triphosphate-linked concentration of calcium ions in a particulate fraction of rabbit muscle
-
19866605
-
Ebashi S, Lipmann F. Adenosine triphosphate-linked concentration of calcium ions in a particulate fraction of rabbit muscle. J Cell Biol 1962; 14:389-400; PMID:19866605; http://dx.doi.org/10.1083/jcb.14.3.389
-
(1962)
J Cell Biol
, vol.14
, pp. 389-400
-
-
Ebashi, S.1
Lipmann, F.2
-
7
-
-
0014107420
-
Lipid synthesis, intracellular transport, and secretion. II. Electron microscopic radioautographic study of the mouse lactating mammary gland
-
6033535
-
Stein O, Stein Y. Lipid synthesis, intracellular transport, and secretion. II. Electron microscopic radioautographic study of the mouse lactating mammary gland. J Cell Biol 1967; 34:251-63; PMID:6033535; http://dx.doi.org/10.1083/jcb.34.1.251
-
(1967)
J Cell Biol
, vol.34
, pp. 251-263
-
-
Stein, O.1
Stein, Y.2
-
8
-
-
0001174553
-
Ribosome/membrane interaction in eukaryotic cells
-
http://dx.doi.org/
-
Blobel G, Sabatini DD. Ribosome/membrane interaction in eukaryotic cells. Biomembranes 1971; 2:193-5; http://dx.doi.org/10.1007/978-1-4684-3330-2_16
-
(1971)
Biomembranes
, vol.2
, pp. 193-195
-
-
Blobel, G.1
Sabatini, D.D.2
-
9
-
-
0016752682
-
Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components
-
811672
-
Blobel G, Dobberstein B. Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components. J Cell Biol 1975; 67:852-62; PMID:811672; http://dx.doi.org/10.1083/jcb.67.3.852
-
(1975)
J Cell Biol
, vol.67
, pp. 852-862
-
-
Blobel, G.1
Dobberstein, B.2
-
10
-
-
0018587968
-
Translocation of proteins across membranes: the signal hypothesis and beyond
-
524275,; PMID
-
Blobel G, Walter P, Chang CN, Goldman BM, Erickson AH, Lingappa VR. Translocation of proteins across membranes: the signal hypothesis and beyond. Symp Soc Exp Biol 1979; 33:9-36; PMID:524275
-
(1979)
Symp Soc Exp Biol
, vol.33
, pp. 9-36
-
-
Blobel, G.1
Walter, P.2
Chang, C.N.3
Goldman, B.M.4
Erickson, A.H.5
Lingappa, V.R.6
-
11
-
-
0020413603
-
Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor
-
6292236
-
Gilmore R, Walter P, Blobel G. Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor. J Cell Biol 1982; 95:470-7; PMID:6292236; http://dx.doi.org/10.1083/jcb.95.2.470
-
(1982)
J Cell Biol
, vol.95
, pp. 470-477
-
-
Gilmore, R.1
Walter, P.2
Blobel, G.3
-
12
-
-
0019964240
-
Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum
-
6181418
-
Walter P, Blobel G. Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum. Nature 1982; 299:691-8; PMID:6181418; http://dx.doi.org/10.1038/299691a0
-
(1982)
Nature
, vol.299
, pp. 691-698
-
-
Walter, P.1
Blobel, G.2
-
13
-
-
0015955240
-
Isolation of a high affinity calcium-binding protein from sarcoplasmic reticulum
-
4272851,; PMID
-
Ostwald TJ, MacLennan DH. Isolation of a high affinity calcium-binding protein from sarcoplasmic reticulum. J Biol Chem 1974; 249:974-9; PMID:4272851
-
(1974)
J Biol Chem
, vol.249
, pp. 974-979
-
-
Ostwald, T.J.1
MacLennan, D.H.2
-
14
-
-
0023652396
-
A C-terminal signal prevents secretion of luminal ER proteins
-
3545499
-
Munro S, Pelham HR. A C-terminal signal prevents secretion of luminal ER proteins. Cell 1987; 48:899-907; PMID:3545499; http://dx.doi.org/10.1016/0092-8674(87)90086-9
-
(1987)
Cell
, vol.48
, pp. 899-907
-
-
Munro, S.1
Pelham, H.R.2
-
15
-
-
0023749075
-
Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins
-
3292055
-
Lippincott-Schwartz J, Bonifacino JS, Yuan LC, Klausner RD. Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins. Cell 1988; 54:209-20; PMID:3292055; http://dx.doi.org/10.1016/0092-8674(88)90553-3
-
(1988)
Cell
, vol.54
, pp. 209-220
-
-
Lippincott-Schwartz, J.1
Bonifacino, J.S.2
Yuan, L.C.3
Klausner, R.D.4
-
16
-
-
56749176947
-
One step at a time: endoplasmic reticulum-associated degradation
-
19002207
-
Vembar SS, Brodsky JL. One step at a time: endoplasmic reticulum-associated degradation. Nat Rev Mol Cell Biol 2008; 9:944-57; PMID:19002207; http://dx.doi.org/10.1038/nrm2546
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 944-957
-
-
Vembar, S.S.1
Brodsky, J.L.2
-
17
-
-
0030070704
-
Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP
-
8636208
-
McCracken AA, Brodsky JL. Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP. J Cell Biol 1996; 132:291-8; PMID:8636208; http://dx.doi.org/10.1083/jcb.132.3.291
-
(1996)
J Cell Biol
, vol.132
, pp. 291-298
-
-
McCracken, A.A.1
Brodsky, J.L.2
-
18
-
-
0026628290
-
A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins
-
1628622,; PMID
-
Mori K, Sant A, Kohno K, Normington K, Gething MJ, Sambrook JF. A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins. EMBO J 1992; 11:2583-93; PMID:1628622
-
(1992)
EMBO J
, vol.11
, pp. 2583-2593
-
-
Mori, K.1
Sant, A.2
Kohno, K.3
Normington, K.4
Gething, M.J.5
Sambrook, J.F.6
-
19
-
-
0027324844
-
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase
-
8513503
-
Cox JS, Shamu CE, Walter P. Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 1993; 73:1197-206; PMID:8513503; http://dx.doi.org/10.1016/0092-8674(93)90648-A
-
(1993)
Cell
, vol.73
, pp. 1197-1206
-
-
Cox, J.S.1
Shamu, C.E.2
Walter, P.3
-
20
-
-
0027305620
-
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus
-
8358794
-
Mori K, Ma W, Gething MJ, Sambrook J. A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 1993; 74:743-56; PMID:8358794; http://dx.doi.org/10.1016/0092-8674(93)90521-Q
-
(1993)
Cell
, vol.74
, pp. 743-756
-
-
Mori, K.1
Ma, W.2
Gething, M.J.3
Sambrook, J.4
-
21
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
9930704
-
Harding HP, Zhang Y, Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 1999; 397:271-4; PMID:9930704; http://dx.doi.org/10.1038/16729
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
22
-
-
0031755020
-
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control
-
9819435,; PMID
-
Shi Y, Vattem KM, Sood R, An J, Liang J, Stramm L, Wek RC. Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol Cell Biol 1998; 18:7499-509; PMID:9819435
-
(1998)
Mol Cell Biol
, vol.18
, pp. 7499-7509
-
-
Shi, Y.1
Vattem, K.M.2
Sood, R.3
An, J.4
Liang, J.5
Stramm, L.6
Wek, R.C.7
-
23
-
-
0033634641
-
Perk is essential for translational regulation and cell survival during the unfolded protein response
-
10882126
-
Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D. Perk is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 2000; 5:897-904; PMID:10882126; http://dx.doi.org/10.1016/S1097-2765(00)80330-5
-
(2000)
Mol Cell
, vol.5
, pp. 897-904
-
-
Harding, H.P.1
Zhang, Y.2
Bertolotti, A.3
Zeng, H.4
Ron, D.5
-
24
-
-
0032693671
-
Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress
-
10564271
-
Haze K, Yoshida H, Yanagi H, Yura T, Mori K. Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol Biol Cell 1999; 10:3787-99; PMID:10564271; http://dx.doi.org/10.1091/mbc.10.11.3787
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3787-3799
-
-
Haze, K.1
Yoshida, H.2
Yanagi, H.3
Yura, T.4
Mori, K.5
-
25
-
-
84900312241
-
Endoplasmic reticulum stress in malignancy
-
24823636
-
Clarke HJ, Chambers JE, Liniker E, Marciniak SJ. Endoplasmic reticulum stress in malignancy. Cancer cell 2014; 25:563-73; PMID:24823636; http://dx.doi.org/10.1016/j.ccr.2014.03.015
-
(2014)
Cancer cell
, vol.25
, pp. 563-573
-
-
Clarke, H.J.1
Chambers, J.E.2
Liniker, E.3
Marciniak, S.J.4
-
26
-
-
84883387793
-
Targeting the unfolded protein response in disease
-
23989796
-
Hetz C, Chevet E, Harding HP. Targeting the unfolded protein response in disease. Nat Rev Drug Discov 2013; 12:703-19; PMID:23989796; http://dx.doi.org/10.1038/nrd3976
-
(2013)
Nat Rev Drug Discov
, vol.12
, pp. 703-719
-
-
Hetz, C.1
Chevet, E.2
Harding, H.P.3
-
27
-
-
79958033194
-
Modulating stress responses by the UPRosome: a matter of life and death
-
21482118
-
Woehlbier U, Hetz C. Modulating stress responses by the UPRosome: a matter of life and death. Trends Biochem Sci 2011; 36:329-37; PMID:21482118; http://dx.doi.org/10.1016/j.tibs.2011.03.001
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 329-337
-
-
Woehlbier, U.1
Hetz, C.2
-
28
-
-
26444442450
-
Endoplasmic reticulum stress: cell life and death decisions
-
16200199
-
Xu C, Bailly-Maitre B, Reed JC. Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 2005; 115:2656-64; PMID:16200199; http://dx.doi.org/10.1172/JCI26373
-
(2005)
J Clin Invest
, vol.115
, pp. 2656-2664
-
-
Xu, C.1
Bailly-Maitre, B.2
Reed, J.C.3
-
29
-
-
84866932320
-
ER stress-induced inflammation: does it aid or impede disease progression
-
22883813
-
Garg AD, Kaczmarek A, Krysko O, Vandenabeele P, Krysko DV, Agostinis P. ER stress-induced inflammation: does it aid or impede disease progression? Trends Mol Med 2012; 18:589-98; PMID:22883813; http://dx.doi.org/10.1016/j.molmed.2012.06.010
-
(2012)
Trends Mol Med
, vol.18
, pp. 589-598
-
-
Garg, A.D.1
Kaczmarek, A.2
Krysko, O.3
Vandenabeele, P.4
Krysko, D.V.5
Agostinis, P.6
-
30
-
-
10644233167
-
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
-
15601821
-
Marciniak SJ, Yun CY, Oyadomari S, Novoa I, Zhang Y, Jungreis R, Nagata K, Harding HP, Ron D. CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum. Genes Dev 2004; 18:3066-77; PMID:15601821; http://dx.doi.org/10.1101/gad.1250704
-
(2004)
Genes Dev
, vol.18
, pp. 3066-3077
-
-
Marciniak, S.J.1
Yun, C.Y.2
Oyadomari, S.3
Novoa, I.4
Zhang, Y.5
Jungreis, R.6
Nagata, K.7
Harding, H.P.8
Ron, D.9
-
31
-
-
33845459165
-
Autophagy is activated for cell survival after endoplasmic reticulum stress
-
17030611
-
Ogata M, Hino S, Saito A, Morikawa K, Kondo S, Kanemoto S, Murakami T, Taniguchi M, Tanii I, Yoshinaga K, et al. Autophagy is activated for cell survival after endoplasmic reticulum stress. Mol Cell Biol 2006; 26:9220-31; PMID:17030611; http://dx.doi.org/10.1128/MCB.01453-06
-
(2006)
Mol Cell Biol
, vol.26
, pp. 9220-9231
-
-
Ogata, M.1
Hino, S.2
Saito, A.3
Morikawa, K.4
Kondo, S.5
Kanemoto, S.6
Murakami, T.7
Taniguchi, M.8
Tanii, I.9
Yoshinaga, K.10
-
32
-
-
33845480131
-
Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response
-
17132049,; PMID
-
Bernales S, McDonald KL, Walter P. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol 2006; 4:e423; PMID:17132049
-
(2006)
PLoS Biol
, vol.4
, pp. e423
-
-
Bernales, S.1
McDonald, K.L.2
Walter, P.3
-
33
-
-
84855799966
-
The ER-mitochondria interface: the social network of cell death
-
22182703
-
Grimm S. The ER-mitochondria interface: the social network of cell death. Biochim Biophys Acta 2012; 1823:327-34; PMID:22182703; http://dx.doi.org/10.1016/j.bbamcr.2011.11.018
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 327-334
-
-
Grimm, S.1
-
34
-
-
84905043685
-
At the right distance: ER-mitochondria juxtaposition in cell life and death
-
24875902
-
Naon D, Scorrano L. At the right distance: ER-mitochondria juxtaposition in cell life and death. Biochim Biophys Acta 2014; 1843:2184-94; PMID:24875902; http://dx.doi.org/10.1016/j.bbamcr.2014.05.011
-
(2014)
Biochim Biophys Acta
, vol.1843
, pp. 2184-2194
-
-
Naon, D.1
Scorrano, L.2
-
35
-
-
84870984470
-
PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
-
22705852
-
Verfaillie T, Rubio N, Garg AD, Bultynck G, Rizzuto R, Decuypere JP, Piette J, Linehan C, Gupta S, Samali A, et al. PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress. Cell Death Differ 2012; 19:1880-91; PMID:22705852; http://dx.doi.org/10.1038/cdd.2012.74
-
(2012)
Cell Death Differ
, vol.19
, pp. 1880-1891
-
-
Verfaillie, T.1
Rubio, N.2
Garg, A.D.3
Bultynck, G.4
Rizzuto, R.5
Decuypere, J.P.6
Piette, J.7
Linehan, C.8
Gupta, S.9
Samali, A.10
-
36
-
-
10344222124
-
The role of the unfolded protein response in tumour development: friend or foe
-
15573118
-
Ma Y, Hendershot LM. The role of the unfolded protein response in tumour development: friend or foe? Nat Rev Cancer 2004; 4:966-77; PMID:15573118; http://dx.doi.org/10.1038/nrc1505
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 966-977
-
-
Ma, Y.1
Hendershot, L.M.2
-
37
-
-
0029817451
-
Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME
-
8755537
-
Jamora C, Dennert G, Lee AS. Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. Proc Natl Acad Sci U S A 1996; 93:7690-4; PMID:8755537; http://dx.doi.org/10.1073/pnas.93.15.7690
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 7690-7694
-
-
Jamora, C.1
Dennert, G.2
Lee, A.S.3
-
38
-
-
0035872446
-
Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone
-
11358846,; PMID
-
Ozawa K, Tsukamoto Y, Hori O, Kitao Y, Yanagi H, Stern DM, Ogawa S. Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone. Cancer Res 2001; 61:4206-13; PMID:11358846
-
(2001)
Cancer Res
, vol.61
, pp. 4206-4213
-
-
Ozawa, K.1
Tsukamoto, Y.2
Hori, O.3
Kitao, Y.4
Yanagi, H.5
Stern, D.M.6
Ogawa, S.7
-
39
-
-
4344660747
-
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
-
15342372
-
Romero-Ramirez L, Cao H, Nelson D, Hammond E, Lee AH, Yoshida H, Mori K, Glimcher LH, Denko NC, Giaccia AJ, et al. XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer Res 2004; 64:5943-7; PMID:15342372; http://dx.doi.org/10.1158/0008-5472.CAN-04-1606
-
(2004)
Cancer Res
, vol.64
, pp. 5943-5947
-
-
Romero-Ramirez, L.1
Cao, H.2
Nelson, D.3
Hammond, E.4
Lee, A.H.5
Yoshida, H.6
Mori, K.7
Glimcher, L.H.8
Denko, N.C.9
Giaccia, A.J.10
-
40
-
-
84876098009
-
Targeting ER stress induced apoptosis and inflammation in cancer
-
20732741
-
Verfaillie T, Garg AD, Agostinis P. Targeting ER stress induced apoptosis and inflammation in cancer. Cancer Lett 2013; 332:249-64; PMID:20732741; http://dx.doi.org/10.1016/j.canlet.2010.07.016
-
(2013)
Cancer Lett
, vol.332
, pp. 249-264
-
-
Verfaillie, T.1
Garg, A.D.2
Agostinis, P.3
-
41
-
-
36348943088
-
Integrated endoplasmic reticulum stress responses in cancer
-
18006802
-
Moenner M, Pluquet O, Bouchecareilh M, Chevet E. Integrated endoplasmic reticulum stress responses in cancer. Cancer Res 2007; 67:10631-4; PMID:18006802; http://dx.doi.org/10.1158/0008-5472.CAN-07-1705
-
(2007)
Cancer Res
, vol.67
, pp. 10631-10634
-
-
Moenner, M.1
Pluquet, O.2
Bouchecareilh, M.3
Chevet, E.4
-
42
-
-
84899940537
-
Addicted to secrete—novel concepts and targets in cancer therapy
-
24456621
-
Dejeans N, Manie S, Hetz C, Bard F, Hupp T, Agostinis P, Samali A, Chevet E. Addicted to secrete—novel concepts and targets in cancer therapy. Trends Mol Med 2014; 20:242-50; PMID:24456621; http://dx.doi.org/10.1016/j.molmed.2013.12.003
-
(2014)
Trends Mol Med
, vol.20
, pp. 242-250
-
-
Dejeans, N.1
Manie, S.2
Hetz, C.3
Bard, F.4
Hupp, T.5
Agostinis, P.6
Samali, A.7
Chevet, E.8
-
43
-
-
77957288028
-
Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma
-
20702765
-
Auf G, Jabouille A, Guerit S, Pineau R, Delugin M, Bouchecareilh M, Magnin N, Favereaux A, Maitre M, Gaiser T, et al. Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma. Proc Natl Acad Sci U S A 2010; 107:15553-8; PMID:20702765; http://dx.doi.org/10.1073/pnas.0914072107
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15553-15558
-
-
Auf, G.1
Jabouille, A.2
Guerit, S.3
Pineau, R.4
Delugin, M.5
Bouchecareilh, M.6
Magnin, N.7
Favereaux, A.8
Maitre, M.9
Gaiser, T.10
-
44
-
-
27144458505
-
ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth
-
16148948
-
Bi M, Naczki C, Koritzinsky M, Fels D, Blais J, Hu N, Harding H, Novoa I, Varia M, Raleigh J, et al. ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth. EMBO J 2005; 24:3470-81; PMID:16148948; http://dx.doi.org/10.1038/sj.emboj.7600777
-
(2005)
EMBO J
, vol.24
, pp. 3470-3481
-
-
Bi, M.1
Naczki, C.2
Koritzinsky, M.3
Fels, D.4
Blais, J.5
Hu, N.6
Harding, H.7
Novoa, I.8
Varia, M.9
Raleigh, J.10
-
45
-
-
33845465578
-
Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress
-
17030613
-
Blais JD, Addison CL, Edge R, Falls T, Zhao H, Wary K, Koumenis C, Harding HP, Ron D, Holcik M, et al. Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress. Mol Cell Biol 2006; 26:9517-32; PMID:17030613; http://dx.doi.org/10.1128/MCB.01145-06
-
(2006)
Mol Cell Biol
, vol.26
, pp. 9517-9532
-
-
Blais, J.D.1
Addison, C.L.2
Edge, R.3
Falls, T.4
Zhao, H.5
Wary, K.6
Koumenis, C.7
Harding, H.P.8
Ron, D.9
Holcik, M.10
-
46
-
-
77954535031
-
PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage
-
20453876
-
Bobrovnikova-Marjon E, Grigoriadou C, Pytel D, Zhang F, Ye J, Koumenis C, Cavener D, Diehl JA. PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage. Oncogene 2010; 29:3881-95; PMID:20453876; http://dx.doi.org/10.1038/onc.2010.153
-
(2010)
Oncogene
, vol.29
, pp. 3881-3895
-
-
Bobrovnikova-Marjon, E.1
Grigoriadou, C.2
Pytel, D.3
Zhang, F.4
Ye, J.5
Koumenis, C.6
Cavener, D.7
Diehl, J.A.8
-
47
-
-
34547114745
-
IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo
-
17638880
-
Drogat B, Auguste P, Nguyen DT, Bouchecareilh M, Pineau R, Nalbantoglu J, Kaufman RJ, Chevet E, Bikfalvi A, Moenner M. IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo. Cancer Res 2007; 67:6700-7; PMID:17638880; http://dx.doi.org/10.1158/0008-5472.CAN-06-3235
-
(2007)
Cancer Res
, vol.67
, pp. 6700-6707
-
-
Drogat, B.1
Auguste, P.2
Nguyen, D.T.3
Bouchecareilh, M.4
Pineau, R.5
Nalbantoglu, J.6
Kaufman, R.J.7
Chevet, E.8
Bikfalvi, A.9
Moenner, M.10
-
48
-
-
84875811673
-
p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose
-
23395000
-
Huber AL, Lebeau J, Guillaumot P, Petrilli V, Malek M, Chilloux J, Fauvet F, Payen L, Kfoury A, Renno T, et al. p58(IPK)-mediated attenuation of the proapoptotic PERK-CHOP pathway allows malignant progression upon low glucose. Mol Cell 2013; 49:1049-59; PMID:23395000; http://dx.doi.org/10.1016/j.molcel.2013.01.009
-
(2013)
Mol Cell
, vol.49
, pp. 1049-1059
-
-
Huber, A.L.1
Lebeau, J.2
Guillaumot, P.3
Petrilli, V.4
Malek, M.5
Chilloux, J.6
Fauvet, F.7
Payen, L.8
Kfoury, A.9
Renno, T.10
-
49
-
-
84867562151
-
The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathway
-
22915762
-
Wang Y, Alam GN, Ning Y, Visioli F, Dong Z, Nor JE, Polverini PJ. The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathway. Cancer Res 2012; 72:5396-406; PMID:22915762; http://dx.doi.org/10.1158/0008-5472.CAN-12-0474
-
(2012)
Cancer Res
, vol.72
, pp. 5396-5406
-
-
Wang, Y.1
Alam, G.N.2
Ning, Y.3
Visioli, F.4
Dong, Z.5
Nor, J.E.6
Polverini, P.J.7
-
50
-
-
26844468253
-
Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte
-
16239148
-
Gardai SJ, McPhillips KA, Frasch SC, Janssen WJ, Starefeldt A, Murphy-Ullrich JE, Bratton DL, Oldenborg PA, Michalak M, Henson PM. Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte. Cell 2005; 123:321-34; PMID:16239148; http://dx.doi.org/10.1016/j.cell.2005.08.032
-
(2005)
Cell
, vol.123
, pp. 321-334
-
-
Gardai, S.J.1
McPhillips, K.A.2
Frasch, S.C.3
Janssen, W.J.4
Starefeldt, A.5
Murphy-Ullrich, J.E.6
Bratton, D.L.7
Oldenborg, P.A.8
Michalak, M.9
Henson, P.M.10
-
51
-
-
33846057130
-
Calreticulin exposure dictates the immunogenicity of cancer cell death
-
17187072
-
Obeid M, Tesniere A, Ghiringhelli F, Fimia GM, Apetoh L, Perfettini JL, Castedo M, Mignot G, Panaretakis T, Casares N, et al. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med 2007; 13:54-61; PMID:17187072; http://dx.doi.org/10.1038/nm1523
-
(2007)
Nat Med
, vol.13
, pp. 54-61
-
-
Obeid, M.1
Tesniere, A.2
Ghiringhelli, F.3
Fimia, G.M.4
Apetoh, L.5
Perfettini, J.L.6
Castedo, M.7
Mignot, G.8
Panaretakis, T.9
Casares, N.10
-
52
-
-
84858000639
-
Enlightening the impact of immunogenic cell death in photodynamic cancer therapy
-
22252132,; MID:,; http://dx.doi.org/
-
Galluzzi L, Kepp O, Kroemer G. Enlightening the impact of immunogenic cell death in photodynamic cancer therapy. EMBO J 2012; 31:1055-7; MID:22252132; http://dx.doi.org/10.1038/emboj.2012.2
-
(2012)
EMBO J
, vol.31
, pp. 1055-1057
-
-
Galluzzi, L.1
Kepp, O.2
Kroemer, G.3
-
53
-
-
77953701142
-
Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway
-
20421432
-
Zitvogel L, Kepp O, Senovilla L, Menger L, Chaput N, Kroemer G. Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway. Clin Cancer Res 2010; 16:3100-4; PMID:20421432; http://dx.doi.org/10.1158/1078-0432.CCR-09-2891
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3100-3104
-
-
Zitvogel, L.1
Kepp, O.2
Senovilla, L.3
Menger, L.4
Chaput, N.5
Kroemer, G.6
-
54
-
-
84894445642
-
ER stress, autophagy and immunogenic cell death in photodynamic therapy-induced anti-cancer immune responses
-
24493131
-
Garg AD, Agostinis P. ER stress, autophagy and immunogenic cell death in photodynamic therapy-induced anti-cancer immune responses. Photochem Photobiol Sci 2014; 13:474-87; PMID:24493131; http://dx.doi.org/10.1039/c3pp50333j
-
(2014)
Photochem Photobiol Sci
, vol.13
, pp. 474-487
-
-
Garg, A.D.1
Agostinis, P.2
-
55
-
-
84856696459
-
Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin
-
22193987
-
Garg AD, Krysko DV, Vandenabeele P, Agostinis P. Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin. Cancer Immunol Immunother 2012; 61:215-21; PMID:22193987; http://dx.doi.org/10.1007/s00262-011-1184-2
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 215-221
-
-
Garg, A.D.1
Krysko, D.V.2
Vandenabeele, P.3
Agostinis, P.4
-
56
-
-
84857997683
-
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
-
22252128,; PMID
-
Garg AD, Krysko DV, Verfaillie T, Kaczmarek A, Ferreira GB, Marysael T, Rubio N, Firczuk M, Mathieu C, Roebroek AJ, et al. A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J 2012; 31:1062-79; PMID:22252128
-
(2012)
EMBO J
, vol.31
, pp. 1062-1079
-
-
Garg, A.D.1
Krysko, D.V.2
Verfaillie, T.3
Kaczmarek, A.4
Ferreira, G.B.5
Marysael, T.6
Rubio, N.7
Firczuk, M.8
Mathieu, C.9
Roebroek, A.J.10
-
57
-
-
62049085194
-
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
-
19165151
-
Panaretakis T, Kepp O, Brockmeier U, Tesniere A, Bjorklund AC, Chapman DC, Durchschlag M, Joza N, Pierron G, van Endert P, et al. Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death. EMBO J 2009; 28:578-90; PMID:19165151; http://dx.doi.org/10.1038/emboj.2009.1
-
(2009)
EMBO J
, vol.28
, pp. 578-590
-
-
Panaretakis, T.1
Kepp, O.2
Brockmeier, U.3
Tesniere, A.4
Bjorklund, A.C.5
Chapman, D.C.6
Durchschlag, M.7
Joza, N.8
Pierron, G.9
van Endert, P.10
-
58
-
-
84866905708
-
Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-p yrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK)
-
http://dx.doi.org/
-
Axten JM, Medina JR, Feng Y, Shu A, Romeril SP, Grant SW, Li WH, Heerding DA, Minthorn E, Mencken T, et al. Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-p yrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). J Med Chem 2012; 55:7193-207; http://dx.doi.org/10.1021/jm300713s
-
(2012)
J Med Chem
, vol.55
, pp. 7193-7207
-
-
Axten, J.M.1
Medina, J.R.2
Feng, Y.3
Shu, A.4
Romeril, S.P.5
Grant, S.W.6
Li, W.H.7
Heerding, D.A.8
Minthorn, E.9
Mencken, T.10
-
59
-
-
84875235453
-
Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity
-
23333938
-
Atkins C, Liu Q, Minthorn E, Zhang SY, Figueroa DJ, Moss K, Stanley TB, Sanders B, Goetz A, Gaul N, et al. Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res 2013; 73:1993-2002; PMID:23333938; http://dx.doi.org/10.1158/0008-5472.CAN-12-3109
-
(2013)
Cancer Res
, vol.73
, pp. 1993-2002
-
-
Atkins, C.1
Liu, Q.2
Minthorn, E.3
Zhang, S.Y.4
Figueroa, D.J.5
Moss, K.6
Stanley, T.B.7
Sanders, B.8
Goetz, A.9
Gaul, N.10
-
60
-
-
84862501186
-
Blockade of XBP1 splicing by inhibition of IRE1alpha is a promising therapeutic option in multiple myeloma
-
22538852
-
Mimura N, Fulciniti M, Gorgun G, Tai YT, Cirstea D, Santo L, Hu Y, Fabre C, Minami J, Ohguchi H, et al. Blockade of XBP1 splicing by inhibition of IRE1alpha is a promising therapeutic option in multiple myeloma. Blood 2012; 119:5772-81; PMID:22538852; http://dx.doi.org/10.1182/blood-2011-07-366633
-
(2012)
Blood
, vol.119
, pp. 5772-5781
-
-
Mimura, N.1
Fulciniti, M.2
Gorgun, G.3
Tai, Y.T.4
Cirstea, D.5
Santo, L.6
Hu, Y.7
Fabre, C.8
Minami, J.9
Ohguchi, H.10
-
61
-
-
79251589342
-
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
-
21081713, Van
-
Papandreou I, Denko NC, Olson M, Van Melckebeke H, Lust S, Tam A, Solow-Cordero DE, Bouley DM, Offner F, Niwa M, et al. Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma. Blood 2011; 117:1311-4; PMID:21081713; http://dx.doi.org/10.1182/blood-2010-08-303099
-
(2011)
Blood
, vol.117
, pp. 1311-1314
-
-
Papandreou, I.1
Denko, N.C.2
Olson, M.3
Melckebeke, H.4
Lust, S.5
Tam, A.6
Solow-Cordero, D.E.7
Bouley, D.M.8
Offner, F.9
Niwa, M.10
-
62
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
12826635
-
Richardson PG, Barlogie B, Berenson J, Singhal S, Jagannath S, Irwin D, Rajkumar SV, Srkalovic G, Alsina M, Alexanian R, et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. N Engl J Med 2003; 348:2609-17; PMID:12826635; http://dx.doi.org/10.1056/NEJMoa030288
-
(2003)
N Engl J Med
, vol.348
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhal, S.4
Jagannath, S.5
Irwin, D.6
Rajkumar, S.V.7
Srkalovic, G.8
Alsina, M.9
Alexanian, R.10
-
63
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
21376230
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144:646-74; PMID:21376230; http://dx.doi.org/10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
64
-
-
84879780600
-
Autophagy: shaping the tumor microenvironment and therapeutic response
-
23714574
-
Maes H, Rubio N, Garg AD, Agostinis P. Autophagy: shaping the tumor microenvironment and therapeutic response. Trends Mol Med 2013; 19:428-46; PMID:23714574; http://dx.doi.org/10.1016/j.molmed.2013.04.005
-
(2013)
Trends Mol Med
, vol.19
, pp. 428-446
-
-
Maes, H.1
Rubio, N.2
Garg, A.D.3
Agostinis, P.4
-
65
-
-
47749139256
-
Cancer as an overhealing wound: an old hypothesis revisited
-
18628784
-
Schafer M, Werner S. Cancer as an overhealing wound: an old hypothesis revisited. Nat Rev Mol Cell Biol 2008; 9:628-38; PMID:18628784; http://dx.doi.org/10.1038/nrm2455
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 628-638
-
-
Schafer, M.1
Werner, S.2
-
66
-
-
84883205105
-
The aging of the 2000 and 2011 hallmarks of cancer reviews: a critique
-
23938395
-
Sonnenschein C, Soto AM. The aging of the 2000 and 2011 hallmarks of cancer reviews: a critique. J Biosci 2013; 38:651-63; PMID:23938395; http://dx.doi.org/10.1007/s12038-013-9335-6
-
(2013)
J Biosci
, vol.38
, pp. 651-663
-
-
Sonnenschein, C.1
Soto, A.M.2
-
67
-
-
77950020483
-
What are the hallmarks of cancer?
-
20355252
-
Lazebnik Y. What are the hallmarks of cancer? Nat Rev Cancer 2010; 10:232-3; PMID:20355252; http://dx.doi.org/10.1038/nrc2827
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 232-233
-
-
Lazebnik, Y.1
-
68
-
-
79952590872
-
Immune reactions in benign and malignant melanocytic lesions: lessons for immunotherapy
-
21029398
-
Speeckaert R, van Geel N, Vermaelen KV, Lambert J, Van Gele M, Speeckaert MM, Brochez L. Immune reactions in benign and malignant melanocytic lesions: lessons for immunotherapy. Pigment Cell Melanoma Res 2011; 24:334-44; PMID:21029398; http://dx.doi.org/10.1111/j.1755-148X.2010.00799.x
-
(2011)
Pigment Cell Melanoma Res
, vol.24
, pp. 334-344
-
-
Speeckaert, R.1
van Geel, N.2
Vermaelen, K.V.3
Lambert, J.4
Van Gele, M.5
Speeckaert, M.M.6
Brochez, L.7
-
69
-
-
84904982625
-
The role of MAPK signalling pathways in the response to endoplasmic reticulum stress
-
24440275
-
Darling NJ, Cook SJ. The role of MAPK signalling pathways in the response to endoplasmic reticulum stress. Biochim Biophys Acta 2014; 1843:2150-63; PMID:24440275; http://dx.doi.org/10.1016/j.bbamcr.2014.01.009
-
(2014)
Biochim Biophys Acta
, vol.1843
, pp. 2150-2163
-
-
Darling, N.J.1
Cook, S.J.2
-
70
-
-
79952439364
-
Induction of ER stress protects gastric cancer cells against apoptosis induced by cisplatin and doxorubicin through activation of p38 MAPK
-
21320468
-
Feng R, Zhai WL, Yang HY, Jin H, Zhang QX. Induction of ER stress protects gastric cancer cells against apoptosis induced by cisplatin and doxorubicin through activation of p38 MAPK. Biochem Biophys Res Commun 2011; 406:299-304; PMID:21320468; http://dx.doi.org/10.1016/j.bbrc.2011.02.036
-
(2011)
Biochem Biophys Res Commun
, vol.406
, pp. 299-304
-
-
Feng, R.1
Zhai, W.L.2
Yang, H.Y.3
Jin, H.4
Zhang, Q.X.5
-
71
-
-
84877043719
-
Endoplasmic reticulum stress-induced resistance to doxorubicin is reversed by paeonol treatment in human hepatocellular carcinoma cells
-
23658755
-
Fan L, Song B, Sun G, Ma T, Zhong F, Wei W. Endoplasmic reticulum stress-induced resistance to doxorubicin is reversed by paeonol treatment in human hepatocellular carcinoma cells. PLoS One 2013; 8:e62627; PMID:23658755; http://dx.doi.org/10.1371/journal.pone.0062627
-
(2013)
PLoS One
, vol.8
-
-
Fan, L.1
Song, B.2
Sun, G.3
Ma, T.4
Zhong, F.5
Wei, W.6
-
72
-
-
67649438633
-
Cross-talk between PI3K/Akt and MEK/ERK pathways mediates endoplasmic reticulum stress-induced cell cycle progression and cell death in human hepatocellular carcinoma cells
-
19424594,; PMID
-
Dai R, Chen R, Li H. Cross-talk between PI3K/Akt and MEK/ERK pathways mediates endoplasmic reticulum stress-induced cell cycle progression and cell death in human hepatocellular carcinoma cells. Int J Oncol 2009; 34:1749-57; PMID:19424594
-
(2009)
Int J Oncol
, vol.34
, pp. 1749-1757
-
-
Dai, R.1
Chen, R.2
Li, H.3
-
73
-
-
65949106608
-
Human melanoma cells under endoplasmic reticulum stress acquire resistance to microtubule-targeting drugs through XBP-1-mediated activation of Akt
-
19412428,; PMID
-
Jiang CC, Yang F, Thorne RF, Zhu BK, Hersey P, Zhang XD. Human melanoma cells under endoplasmic reticulum stress acquire resistance to microtubule-targeting drugs through XBP-1-mediated activation of Akt. Neoplasia 2009; 11:436-47; PMID:19412428
-
(2009)
Neoplasia
, vol.11
, pp. 436-447
-
-
Jiang, C.C.1
Yang, F.2
Thorne, R.F.3
Zhu, B.K.4
Hersey, P.5
Zhang, X.D.6
-
74
-
-
79960893483
-
Caspase- and p38-MAPK-dependent induction of apoptosis in A549 lung cancer cells by Newcastle disease virus
-
21625975
-
Bian J, Wang K, Kong X, Liu H, Chen F, Hu M, Zhang X, Jiao X, Ge B, Wu Y, et al. Caspase- and p38-MAPK-dependent induction of apoptosis in A549 lung cancer cells by Newcastle disease virus. Arch Virol 2011; 156:1335-44; PMID:21625975; http://dx.doi.org/10.1007/s00705-011-0987-y
-
(2011)
Arch Virol
, vol.156
, pp. 1335-1344
-
-
Bian, J.1
Wang, K.2
Kong, X.3
Liu, H.4
Chen, F.5
Hu, M.6
Zhang, X.7
Jiao, X.8
Ge, B.9
Wu, Y.10
-
75
-
-
0033605591
-
The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin
-
10085120
-
Assefa Z, Vantieghem A, Declercq W, Vandenabeele P, Vandenheede JR, Merlevede W, de Witte P, Agostinis P. The activation of the c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin. J Biol Chem 1999; 274:8788-96; PMID:10085120; http://dx.doi.org/10.1074/jbc.274.13.8788
-
(1999)
J Biol Chem
, vol.274
, pp. 8788-8796
-
-
Assefa, Z.1
Vantieghem, A.2
Declercq, W.3
Vandenabeele, P.4
Vandenheede, J.R.5
Merlevede, W.6
de Witte, P.7
Agostinis, P.8
-
76
-
-
79957634644
-
Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage
-
20626525
-
Dewaele M, Martinet W, Rubio N, Verfaillie T, de Witte PA, Piette J, Agostinis P. Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage. J Cell Mol Med 2011; 15:1402-14; PMID:20626525; http://dx.doi.org/10.1111/j.1582-4934.2010.01118.x
-
(2011)
J Cell Mol Med
, vol.15
, pp. 1402-1414
-
-
Dewaele, M.1
Martinet, W.2
Rubio, N.3
Verfaillie, T.4
de Witte, P.A.5
Piette, J.6
Agostinis, P.7
-
77
-
-
0027432658
-
Inhibition of epidermal growth factor receptor tyrosine kinase activity by hypericin
-
8267642
-
de Witte P, Agostinis P, Van Lint J, Merlevede W, Vandenheede JR. Inhibition of epidermal growth factor receptor tyrosine kinase activity by hypericin. Biochem Pharmacol 1993; 46:1929-36; PMID:8267642; http://dx.doi.org/10.1016/0006-2952(93)90633-8
-
(1993)
Biochem Pharmacol
, vol.46
, pp. 1929-1936
-
-
de Witte, P.1
Agostinis, P.2
Van Lint, J.3
Merlevede, W.4
Vandenheede, J.R.5
-
78
-
-
0029055829
-
Photosensitized inhibition of growth factor-regulated protein kinases by hypericin
-
7786302
-
Agostinis P, Vandenbogaerde A, Donella-Deana A, Pinna LA, Lee KT, Goris J, Merlevede W, Vandenheede JR, De Witte P. Photosensitized inhibition of growth factor-regulated protein kinases by hypericin. Biochem Pharmacol 1995; 49:1615-22; PMID:7786302; http://dx.doi.org/10.1016/0006-2952(95)00097-J
-
(1995)
Biochem Pharmacol
, vol.49
, pp. 1615-1622
-
-
Agostinis, P.1
Vandenbogaerde, A.2
Donella-Deana, A.3
Pinna, L.A.4
Lee, K.T.5
Goris, J.6
Merlevede, W.7
Vandenheede, J.R.8
De Witte, P.9
-
79
-
-
42949138828
-
GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis
-
18064632
-
Shu CW, Sun FC, Cho JH, Lin CC, Liu PF, Chen PY, Chang MD, Fu HW, Lai YK. GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis. J Cell Physiol 2008; 215:627-35; PMID:18064632; http://dx.doi.org/10.1002/jcp.21340
-
(2008)
J Cell Physiol
, vol.215
, pp. 627-635
-
-
Shu, C.W.1
Sun, F.C.2
Cho, J.H.3
Lin, C.C.4
Liu, P.F.5
Chen, P.Y.6
Chang, M.D.7
Fu, H.W.8
Lai, Y.K.9
-
80
-
-
84896757312
-
Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma
-
24569374
-
Ma XH, Piao SF, Dey S, McAfee Q, Karakousis G, Villanueva J, Hart LS, Levi S, Hu J, Zhang G, et al. Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma. J Clin Invest 2014; 124:1406-17; PMID:24569374; http://dx.doi.org/10.1172/JCI70454
-
(2014)
J Clin Invest
, vol.124
, pp. 1406-1417
-
-
Ma, X.H.1
Piao, S.F.2
Dey, S.3
McAfee, Q.4
Karakousis, G.5
Villanueva, J.6
Hart, L.S.7
Levi, S.8
Hu, J.9
Zhang, G.10
-
81
-
-
84892558088
-
Endoplasmic reticulum stress activates telomerase
-
24119029
-
Zhou J, Mao B, Zhou Q, Ding D, Wang M, Guo P, Gao Y, Shay JW, Yuan Z, Cong YS. Endoplasmic reticulum stress activates telomerase. Aging cell 2014; 13:197-200; PMID:24119029; http://dx.doi.org/10.1111/acel.12161
-
(2014)
Aging cell
, vol.13
, pp. 197-200
-
-
Zhou, J.1
Mao, B.2
Zhou, Q.3
Ding, D.4
Wang, M.5
Guo, P.6
Gao, Y.7
Shay, J.W.8
Yuan, Z.9
Cong, Y.S.10
-
82
-
-
84899978668
-
TERT attenuated ER stress-induced cell death
-
24746472
-
Hosoi T, Inoue Y, Nakatsu K, Matsushima N, Kiyose N, Shimamoto A, Tahara H, Ozawa K. TERT attenuated ER stress-induced cell death. Biochem Biophys Res Commun 2014; 447:378-82; PMID:24746472; http://dx.doi.org/10.1016/j.bbrc.2014.04.034
-
(2014)
Biochem Biophys Res Commun
, vol.447
, pp. 378-382
-
-
Hosoi, T.1
Inoue, Y.2
Nakatsu, K.3
Matsushima, N.4
Kiyose, N.5
Shimamoto, A.6
Tahara, H.7
Ozawa, K.8
-
83
-
-
84904462047
-
The nuclear receptor PPARbeta/delta promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress
-
24898257
-
Zhu B, Ferry CH, Markell LK, Blazanin N, Glick AB, Gonzalez FJ, Peters JM. The nuclear receptor PPARbeta/delta promotes oncogene-induced cellular senescence through repression of endoplasmic reticulum stress. J Biol Chem 2014:9(29):20102-19; PMID:24898257; http://dx.doi.org/10.1074/jbc.M114.551069
-
(2014)
J Biol Chem
, vol.9
, Issue.29
, pp. 20102-20119
-
-
Zhu, B.1
Ferry, C.H.2
Markell, L.K.3
Blazanin, N.4
Glick, A.B.5
Gonzalez, F.J.6
Peters, J.M.7
-
84
-
-
84902154472
-
Cisplatin-induced senescence in ovarian cancer cells is mediated by GRP78
-
24756776,; PMID
-
Li W, Wang W, Dong H, Li Y, Li L, Han L, Han Z, Wang S, Ma D, Wang H. Cisplatin-induced senescence in ovarian cancer cells is mediated by GRP78. Oncology reports 2014; 31:2525-34; PMID:24756776
-
(2014)
Oncology reports
, vol.31
, pp. 2525-2534
-
-
Li, W.1
Wang, W.2
Dong, H.3
Li, Y.4
Li, L.5
Han, L.6
Han, Z.7
Wang, S.8
Ma, D.9
Wang, H.10
-
85
-
-
79953326730
-
Preclinical evaluation of telomerase-specific oncolytic virotherapy for human bone and soft tissue sarcomas
-
21325287
-
Sasaki T, Tazawa H, Hasei J, Kunisada T, Yoshida A, Hashimoto Y, Yano S, Yoshida R, Uno F, Kagawa S, et al. Preclinical evaluation of telomerase-specific oncolytic virotherapy for human bone and soft tissue sarcomas. Clin Cancer Res 2011; 17:1828-38; PMID:21325287; http://dx.doi.org/10.1158/1078-0432.CCR-10-2066
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1828-1838
-
-
Sasaki, T.1
Tazawa, H.2
Hasei, J.3
Kunisada, T.4
Yoshida, A.5
Hashimoto, Y.6
Yano, S.7
Yoshida, R.8
Uno, F.9
Kagawa, S.10
-
86
-
-
84984580947
-
Telomerase-specific oncolytic adenoviral therapy for orthotopic hepatocellular carcinoma in HBx transgenic mice
-
22886913
-
Lin WH, Yeh SH, Yang WJ, Yeh KH, Fujiwara T, Nii A, Chang SS, Chen PJ. Telomerase-specific oncolytic adenoviral therapy for orthotopic hepatocellular carcinoma in HBx transgenic mice. Int J Cancer 2013; 132:1451-62; PMID:22886913; http://dx.doi.org/10.1002/ijc.27770
-
(2013)
Int J Cancer
, vol.132
, pp. 1451-1462
-
-
Lin, W.H.1
Yeh, S.H.2
Yang, W.J.3
Yeh, K.H.4
Fujiwara, T.5
Nii, A.6
Chang, S.S.7
Chen, P.J.8
-
87
-
-
84884161672
-
Telomerase reverse transcriptase inhibition stimulates cyclooxygenase 2 expression in cancer cells and synergizes with celecoxib to exert anti-cancer effects
-
23681187
-
Liu T, Liang X, Li B, Bjorkholm M, Jia J, Xu D. Telomerase reverse transcriptase inhibition stimulates cyclooxygenase 2 expression in cancer cells and synergizes with celecoxib to exert anti-cancer effects. Br J Cancer 2013; 108:2272-80; PMID:23681187; http://dx.doi.org/10.1038/bjc.2013.208
-
(2013)
Br J Cancer
, vol.108
, pp. 2272-2280
-
-
Liu, T.1
Liang, X.2
Li, B.3
Bjorkholm, M.4
Jia, J.5
Xu, D.6
-
88
-
-
84861569599
-
A new oncolytic adenoviral vector carrying dual tumour suppressor genes shows potent anti-tumour effect
-
21794078
-
Liu XR, Cai Y, Cao X, Wei RC, Li HL, Zhou XM, Zhang KJ, Wu S, Qian QJ, Cheng B, et al. A new oncolytic adenoviral vector carrying dual tumour suppressor genes shows potent anti-tumour effect. J Cell Mol Med 2012; 16:1298-309; PMID:21794078; http://dx.doi.org/10.1111/j.1582-4934.2011.01396.x
-
(2012)
J Cell Mol Med
, vol.16
, pp. 1298-1309
-
-
Liu, X.R.1
Cai, Y.2
Cao, X.3
Wei, R.C.4
Li, H.L.5
Zhou, X.M.6
Zhang, K.J.7
Wu, S.8
Qian, Q.J.9
Cheng, B.10
-
89
-
-
35948936884
-
Hypericium perforatum extract (St. John's Wort) and hypericin induce apoptosis in leukemic HL-60 cells by effecting h-TERT activity
-
Ozen KP, Sahin F, Avci CB, Hisil Y, Gunduz C, Saydam G. Hypericium perforatum extract (St. John's Wort) and hypericin induce apoptosis in leukemic HL-60 cells by effecting h-TERT activity. Turk J Hematol 2007; 24:127-33
-
(2007)
Turk J Hematol
, vol.24
, pp. 127-133
-
-
Ozen, K.P.1
Sahin, F.2
Avci, C.B.3
Hisil, Y.4
Gunduz, C.5
Saydam, G.6
-
90
-
-
77951230294
-
Association between the unfolded protein response, induced by 2-deoxyglucose, and hypersensitivity to cisplatin: a mechanistic study employing molecular genomics
-
20009298,; PMID
-
Gaddameedhi S, Chatterjee S. Association between the unfolded protein response, induced by 2-deoxyglucose, and hypersensitivity to cisplatin: a mechanistic study employing molecular genomics. J Cancer Res Ther 2009; 5 Suppl 1:S61-6; PMID:20009298
-
(2009)
J Cancer Res Ther
, vol.5 Suppl 1
, pp. S61-S66
-
-
Gaddameedhi, S.1
Chatterjee, S.2
-
91
-
-
84884903293
-
ER stress suppresses DNA double-strand break repair and sensitizes tumor cells to ionizing radiation by stimulating proteasomal degradation of Rad51
-
24021650
-
Yamamori T, Meike S, Nagane M, Yasui H, Inanami O. ER stress suppresses DNA double-strand break repair and sensitizes tumor cells to ionizing radiation by stimulating proteasomal degradation of Rad51. FEBS Lett 2013; 587:3348-53; PMID:24021650; http://dx.doi.org/10.1016/j.febslet.2013.08.030
-
(2013)
FEBS Lett
, vol.587
, pp. 3348-3353
-
-
Yamamori, T.1
Meike, S.2
Nagane, M.3
Yasui, H.4
Inanami, O.5
-
92
-
-
84866754237
-
An immunosurveillance mechanism controls cancer cell ploidy
-
23019653
-
Senovilla L, Vitale I, Martins I, Tailler M, Pailleret C, Michaud M, Galluzzi L, Adjemian S, Kepp O, Niso-Santano M, et al. An immunosurveillance mechanism controls cancer cell ploidy. Science 2012; 337:1678-84; PMID:23019653; http://dx.doi.org/10.1126/science.1224922
-
(2012)
Science
, vol.337
, pp. 1678-1684
-
-
Senovilla, L.1
Vitale, I.2
Martins, I.3
Tailler, M.4
Pailleret, C.5
Michaud, M.6
Galluzzi, L.7
Adjemian, S.8
Kepp, O.9
Niso-Santano, M.10
-
93
-
-
0037020254
-
-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis
-
12101183
-
-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis. J Biol Chem 2002; 277:37718-31; PMID:12101183; http://dx.doi.org/10.1074/jbc.M204348200
-
(2002)
J Biol Chem
, vol.277
, pp. 37718-37731
-
-
Vantieghem, A.1
Xu, Y.2
Assefa, Z.3
Piette, J.4
Vandenheede, J.R.5
Merlevede, W.6
De Witte, P.A.7
Agostinis, P.8
-
94
-
-
2942557118
-
Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress
-
14738568
-
Marjon PL, Bobrovnikova-Marjon EV, Abcouwer SF. Expression of the pro-angiogenic factors vascular endothelial growth factor and interleukin-8/CXCL8 by human breast carcinomas is responsive to nutrient deprivation and endoplasmic reticulum stress. Mol Cancer 2004; 3:4; PMID:14738568; http://dx.doi.org/10.1186/1476-4598-3-4
-
(2004)
Mol Cancer
, vol.3
, pp. 4
-
-
Marjon, P.L.1
Bobrovnikova-Marjon, E.V.2
Abcouwer, S.F.3
-
95
-
-
77958611209
-
Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response
-
20824063,; PMID
-
Pereira ER, Liao N, Neale GA, Hendershot LM. Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response. PLoS One 2010; 5:e12521; PMID:20824063
-
(2010)
PLoS One
, vol.5
-
-
Pereira, E.R.1
Liao, N.2
Neale, G.A.3
Hendershot, L.M.4
-
96
-
-
84889250555
-
Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis
-
24093630
-
Bota DA, Alexandru D, Keir ST, Bigner D, Vredenburgh J, Friedman HS. Proteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesis. J Neurosurg 2013; 119:1415-23; PMID:24093630; http://dx.doi.org/10.3171/2013.7.JNS1323
-
(2013)
J Neurosurg
, vol.119
, pp. 1415-1423
-
-
Bota, D.A.1
Alexandru, D.2
Keir, S.T.3
Bigner, D.4
Vredenburgh, J.5
Friedman, H.S.6
-
97
-
-
0035895758
-
Thapsigargin inhibits angiogenesis in the rat isolated aorta: studies on the role of intracellular calcium pools
-
11166281
-
Shukla N, Freeman N, Gadsdon P, Angelini GD, Jeremy JY. Thapsigargin inhibits angiogenesis in the rat isolated aorta: studies on the role of intracellular calcium pools. Cardiovasc Res 2001; 49:681-9; PMID:11166281; http://dx.doi.org/10.1016/S0008-6363(00)00269-8
-
(2001)
Cardiovasc Res
, vol.49
, pp. 681-689
-
-
Shukla, N.1
Freeman, N.2
Gadsdon, P.3
Angelini, G.D.4
Jeremy, J.Y.5
-
98
-
-
31544433927
-
Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells
-
16397231
-
Roccaro AM, Hideshima T, Raje N, Kumar S, Ishitsuka K, Yasui H, Shiraishi N, Ribatti D, Nico B, Vacca A, et al. Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells. Cancer Res 2006; 66:184-91; PMID:16397231; http://dx.doi.org/10.1158/0008-5472.CAN-05-1195
-
(2006)
Cancer Res
, vol.66
, pp. 184-191
-
-
Roccaro, A.M.1
Hideshima, T.2
Raje, N.3
Kumar, S.4
Ishitsuka, K.5
Yasui, H.6
Shiraishi, N.7
Ribatti, D.8
Nico, B.9
Vacca, A.10
-
99
-
-
80051698302
-
Unfolded protein response is required in nu/nu mice microvasculature for treating breast tumor with tunicamycin
-
21676868
-
Banerjee A, Lang JY, Hung MC, Sengupta K, Banerjee SK, Baksi K, Banerjee DK. Unfolded protein response is required in nu/nu mice microvasculature for treating breast tumor with tunicamycin. J Biol Chem 2011; 286:29127-38; PMID:21676868; http://dx.doi.org/10.1074/jbc.M110.169771
-
(2011)
J Biol Chem
, vol.286
, pp. 29127-29138
-
-
Banerjee, A.1
Lang, J.Y.2
Hung, M.C.3
Sengupta, K.4
Banerjee, S.K.5
Baksi, K.6
Banerjee, D.K.7
-
100
-
-
84867798613
-
RL66 a second-generation curcumin analog has potent in vivo and in vitro anticancer activity in ERnegative breast cancer models
-
22971638,; PMID
-
Yadav B, Taurin S, Larsen L, Rosengren RJ. RL66 a second-generation curcumin analog has potent in vivo and in vitro anticancer activity in ERnegative breast cancer models. Int J Oncol 2012; 41:1723-32; PMID:22971638
-
(2012)
Int J Oncol
, vol.41
, pp. 1723-1732
-
-
Yadav, B.1
Taurin, S.2
Larsen, L.3
Rosengren, R.J.4
-
101
-
-
0034902354
-
Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma
-
11350913,; PMID
-
Sunwoo JB, Chen Z, Dong G, Yeh N, Crowl Bancroft C, Sausville E, Adams J, Elliott P, Van Waes C. Novel proteasome inhibitor PS-341 inhibits activation of nuclear factor-kappa B, cell survival, tumor growth, and angiogenesis in squamous cell carcinoma. Clin Cancer Res 2001; 7:1419-28; PMID:11350913
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1419-1428
-
-
Sunwoo, J.B.1
Chen, Z.2
Dong, G.3
Yeh, N.4
Crowl Bancroft, C.5
Sausville, E.6
Adams, J.7
Elliott, P.8
Van Waes, C.9
-
102
-
-
27544503538
-
Anti-angiogenic effect of bortezomib in patients with multiple myeloma
-
16227683
-
Politou M, Naresh K, Terpos E, Crawley D, Lampert I, Apperley JF, Rahemtulla A. Anti-angiogenic effect of bortezomib in patients with multiple myeloma. Acta haematol 2005; 114:170-3; PMID:16227683; http://dx.doi.org/10.1159/000087894
-
(2005)
Acta haematol
, vol.114
, pp. 170-173
-
-
Politou, M.1
Naresh, K.2
Terpos, E.3
Crawley, D.4
Lampert, I.5
Apperley, J.F.6
Rahemtulla, A.7
-
103
-
-
84870239310
-
Immunogenic cell death and DAMPs in cancer therapy
-
23151605
-
Krysko DV, Garg AD, Kaczmarek A, Krysko O, Agostinis P, Vandenabeele P. Immunogenic cell death and DAMPs in cancer therapy. Nat Rev Cancer 2012; 12:860-75; PMID:23151605; http://dx.doi.org/10.1038/nrc3380
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 860-875
-
-
Krysko, D.V.1
Garg, A.D.2
Kaczmarek, A.3
Krysko, O.4
Agostinis, P.5
Vandenabeele, P.6
-
104
-
-
33645971918
-
p53 Status does not affect photodynamic cell killing induced by hypericin
-
16211395
-
Lee HB, Ho AS, Teo SH. p53 Status does not affect photodynamic cell killing induced by hypericin. Cancer Chemother Pharmacol 2006; 58:91-8; PMID:16211395; http://dx.doi.org/10.1007/s00280-005-0131-3
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 91-98
-
-
Lee, H.B.1
Ho, A.S.2
Teo, S.H.3
-
105
-
-
1042266553
-
p53 and stress in the ER
-
14871924
-
Stavridi ES, Halazonetis TD. p53 and stress in the ER. Genes Dev 2004; 18:241-4; PMID:14871924; http://dx.doi.org/10.1101/gad.1181704
-
(2004)
Genes Dev
, vol.18
, pp. 241-244
-
-
Stavridi, E.S.1
Halazonetis, T.D.2
-
106
-
-
79951857650
-
Unfolded protein response in cancer: the physician's perspective
-
21345215
-
Li X, Zhang K, Li Z. Unfolded protein response in cancer: the physician's perspective. J Hematol Oncol 2011; 4:8; PMID:21345215; http://dx.doi.org/10.1186/1756-8722-4-8
-
(2011)
J Hematol Oncol
, vol.4
, pp. 8
-
-
Li, X.1
Zhang, K.2
Li, Z.3
-
107
-
-
84879780600
-
Autophagy: shaping the tumor microenvironment and therapeutic response
-
23714574
-
Maes H, Rubio N, Garg AD, Agostinis P. Autophagy: shaping the tumor microenvironment and therapeutic response. Trends Mol Med 2013; 19:428-46; PMID:23714574; http://dx.doi.org/10.1016/j.molmed.2013.04.005
-
(2013)
Trends Mol Med
, vol.19
, pp. 428-446
-
-
Maes, H.1
Rubio, N.2
Garg, A.D.3
Agostinis, P.4
-
108
-
-
84879607395
-
Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress
-
23052213
-
Deegan S, Saveljeva S, Gorman AM, Samali A. Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress. Cell Mol Life Sci 2013; 70:2425-41; PMID:23052213; http://dx.doi.org/10.1007/s00018-012-1173-4
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 2425-2441
-
-
Deegan, S.1
Saveljeva, S.2
Gorman, A.M.3
Samali, A.4
-
109
-
-
71249141145
-
Mouse MAPC-mediated immunomodulation: Cell-line dependent variation
-
19853014, De
-
Luyckx A, De Somer L, Rutgeerts O, Waer M, Verfaillie CM, Van Gool S, Billiau AD. Mouse MAPC-mediated immunomodulation: Cell-line dependent variation. Exp Hematol 2010; 38:1-2; PMID:19853014; http://dx.doi.org/10.1016/j.exphem.2009.10.009
-
(2010)
Exp Hematol
, vol.38
, pp. 1-2
-
-
Luyckx, A.1
Somer, L.2
Rutgeerts, O.3
Waer, M.4
Verfaillie, C.M.5
Van Gool, S.6
Billiau, A.D.7
-
110
-
-
53549119055
-
Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation
-
18787411
-
Park MA, Zhang G, Martin AP, Hamed H, Mitchell C, Hylemon PB, Graf M, Rahmani M, Ryan K, Liu X, et al. Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation. Cancer Biol Ther 2008; 7:1648-62; PMID:18787411; http://dx.doi.org/10.4161/cbt.7.10.6623
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1648-1662
-
-
Park, M.A.1
Zhang, G.2
Martin, A.P.3
Hamed, H.4
Mitchell, C.5
Hylemon, P.B.6
Graf, M.7
Rahmani, M.8
Ryan, K.9
Liu, X.10
-
111
-
-
84911120364
-
Ampelopsin-induced autophagy protects breast cancer cells from apoptosis through Akt-mTOR pathway via ER stress
-
25088800,; PMID
-
Zhou Y, Liang X, Chang H, Shu F, Wu Y, Zhang T, Fu J, Zhang Q, Zhu J, Mi M. Ampelopsin-induced autophagy protects breast cancer cells from apoptosis through Akt-mTOR pathway via ER stress. Cancer Sci 2014; 105(10):1279-87; PMID:25088800
-
(2014)
Cancer Sci
, vol.105
, Issue.10
, pp. 1279-1287
-
-
Zhou, Y.1
Liang, X.2
Chang, H.3
Shu, F.4
Wu, Y.5
Zhang, T.6
Fu, J.7
Zhang, Q.8
Zhu, J.9
Mi, M.10
-
112
-
-
84903629591
-
Baicalein induces apoptosis and autophagy via endoplasmic reticulum stress in hepatocellular carcinoma cells
-
24995326,; PMID
-
Wang Z, Jiang C, Chen W, Zhang G, Luo D, Cao Y, Wu J, Ding Y, Liu B. Baicalein induces apoptosis and autophagy via endoplasmic reticulum stress in hepatocellular carcinoma cells. BioMed Res Int 2014; 2014:732516; PMID:24995326
-
(2014)
BioMed Res Int
, vol.2014
, pp. 732516
-
-
Wang, Z.1
Jiang, C.2
Chen, W.3
Zhang, G.4
Luo, D.5
Cao, Y.6
Wu, J.7
Ding, Y.8
Liu, B.9
-
113
-
-
66449122303
-
Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells
-
19363292
-
Bellodi C, Lidonnici MR, Hamilton A, Helgason GV, Soliera AR, Ronchetti M, Galavotti S, Young KW, Selmi T, Yacobi R, et al. Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells. J Clin Invest 2009; 119:1109-23; PMID:19363292; http://dx.doi.org/10.1172/JCI35660
-
(2009)
J Clin Invest
, vol.119
, pp. 1109-1123
-
-
Bellodi, C.1
Lidonnici, M.R.2
Hamilton, A.3
Helgason, G.V.4
Soliera, A.R.5
Ronchetti, M.6
Galavotti, S.7
Young, K.W.8
Selmi, T.9
Yacobi, R.10
-
114
-
-
84894464496
-
Resveratrol induced ER expansion and ER caspase-mediated apoptosis in human nasopharyngeal carcinoma cells
-
24264887
-
Chow SE, Kao CH, Liu YT, Cheng ML, Yang YW, Huang YK, Hsu CC, Wang JS. Resveratrol induced ER expansion and ER caspase-mediated apoptosis in human nasopharyngeal carcinoma cells. Apoptosis 2014; 19:527-41; PMID:24264887; http://dx.doi.org/10.1007/s10495-013-0945-0
-
(2014)
Apoptosis
, vol.19
, pp. 527-541
-
-
Chow, S.E.1
Kao, C.H.2
Liu, Y.T.3
Cheng, M.L.4
Yang, Y.W.5
Huang, Y.K.6
Hsu, C.C.7
Wang, J.S.8
-
115
-
-
84881592393
-
Inhibition of autophagy by 3-MA enhances endoplasmic reticulum stress-induced apoptosis in human nasopharyngeal carcinoma cells
-
24137459,; PMID
-
Song L, Liu H, Ma L, Zhang X, Jiang Z, Jiang C. Inhibition of autophagy by 3-MA enhances endoplasmic reticulum stress-induced apoptosis in human nasopharyngeal carcinoma cells. Oncol Lett 2013; 6:1031-8; PMID:24137459
-
(2013)
Oncol Lett
, vol.6
, pp. 1031-1038
-
-
Song, L.1
Liu, H.2
Ma, L.3
Zhang, X.4
Jiang, Z.5
Jiang, C.6
-
116
-
-
84884626755
-
JNK and macroautophagy activation by bortezomib has a pro-survival effect in primary effusion lymphoma cells
-
Granato M, Santarelli R, Lotti LV, Di Renzo L, Gonnella R, Garufi A, Trivedi P, Frati L, D'Orazi G, Faggioni A, et al. JNK and macroautophagy activation by bortezomib has a pro-survival effect in primary effusion lymphoma cells. PLoS One 2013; 8:e75965
-
(2013)
PLoS One
, vol.8
-
-
Granato, M.1
Santarelli, R.2
Lotti, L.V.3
Di Renzo, L.4
Gonnella, R.5
Garufi, A.6
Trivedi, P.7
Frati, L.8
D'Orazi, G.9
Faggioni, A.10
-
117
-
-
84884253766
-
B19, a novel monocarbonyl analogue of curcumin, induces human ovarian cancer cell apoptosis via activation of endoplasmic reticulum stress and the autophagy signaling pathway
-
23983610
-
Qu W, Xiao J, Zhang H, Chen Q, Wang Z, Shi H, Gong L, Chen J, Liu Y, Cao R, et al. B19, a novel monocarbonyl analogue of curcumin, induces human ovarian cancer cell apoptosis via activation of endoplasmic reticulum stress and the autophagy signaling pathway. IntJ Biol Sci 2013; 9:766-77; PMID:23983610; http://dx.doi.org/10.7150/ijbs.5711
-
(2013)
IntJ Biol Sci
, vol.9
, pp. 766-777
-
-
Qu, W.1
Xiao, J.2
Zhang, H.3
Chen, Q.4
Wang, Z.5
Shi, H.6
Gong, L.7
Chen, J.8
Liu, Y.9
Cao, R.10
-
118
-
-
66449115318
-
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
-
19425170
-
Salazar M, Carracedo A, Salanueva IJ, Hernandez-Tiedra S, Lorente M, Egia A, Vazquez P, Blazquez C, Torres S, Garcia S, et al. Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J Clin Invest 2009; 119:1359-72; PMID:19425170; http://dx.doi.org/10.1172/JCI37948
-
(2009)
J Clin Invest
, vol.119
, pp. 1359-1372
-
-
Salazar, M.1
Carracedo, A.2
Salanueva, I.J.3
Hernandez-Tiedra, S.4
Lorente, M.5
Egia, A.6
Vazquez, P.7
Blazquez, C.8
Torres, S.9
Garcia, S.10
-
119
-
-
38049093745
-
Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy
-
18000394
-
Gills JJ, Lopiccolo J, Dennis PA. Nelfinavir, a new anti-cancer drug with pleiotropic effects and many paths to autophagy. Autophagy 2008; 4:107-9; PMID:18000394; http://dx.doi.org/10.4161/auto.5224
-
(2008)
Autophagy
, vol.4
, pp. 107-109
-
-
Gills, J.J.1
Lopiccolo, J.2
Dennis, P.A.3
-
120
-
-
85051764655
-
Yessotoxin induces Er-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3
-
24514040,; PMID
-
Rubiolo JA, Lopez-Alonso H, Martinez P, Millan A, Cagide E, Vieytes MR, Vega FV, Botana LM. Yessotoxin induces Er-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3. Cell Aignal 2013; PMID:24514040
-
(2013)
Cell Aignal
-
-
Rubiolo, J.A.1
Lopez-Alonso, H.2
Martinez, P.3
Millan, A.4
Cagide, E.5
Vieytes, M.R.6
Vega, F.V.7
Botana, L.M.8
-
121
-
-
33947497050
-
Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival
-
17135238
-
Ding WX, Ni HM, Gao W, Hou YF, Melan MA, Chen X, Stolz DB, Shao ZM, Yin XM. Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. J Biol Chem 2007; 282:4702-10; PMID:17135238; http://dx.doi.org/10.1074/jbc.M609267200
-
(2007)
J Biol Chem
, vol.282
, pp. 4702-4710
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Hou, Y.F.4
Melan, M.A.5
Chen, X.6
Stolz, D.B.7
Shao, Z.M.8
Yin, X.M.9
-
122
-
-
79954609211
-
Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition
-
21270111, Al
-
Armstrong JL, Corazzari M, Martin S, Pagliarini V, Falasca L, Hill DS, Ellis N, Al Sabah S, Redfern CP, Fimia GM, et al. Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition. Clin Cancer Res 2011; 17:2216-26; PMID:21270111; http://dx.doi.org/10.1158/1078-0432.CCR-10-3003
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2216-2226
-
-
Armstrong, J.L.1
Corazzari, M.2
Martin, S.3
Pagliarini, V.4
Falasca, L.5
Hill, D.S.6
Ellis, N.7
Sabah, S.8
Redfern, C.P.9
Fimia, G.M.10
-
123
-
-
84879783969
-
ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death
-
23800749
-
Garg AD, Dudek AM, Ferreira GB, Verfaillie T, Vandenabeele P, Krysko DV, Mathieu C, Agostinis P. ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death. Autophagy 2013; 9:1292-307; PMID:23800749; http://dx.doi.org/10.4161/auto.25399
-
(2013)
Autophagy
, vol.9
, pp. 1292-1307
-
-
Garg, A.D.1
Dudek, A.M.2
Ferreira, G.B.3
Verfaillie, T.4
Vandenabeele, P.5
Krysko, D.V.6
Mathieu, C.7
Agostinis, P.8
-
124
-
-
84904053401
-
Epithelial-to-mesenchymal transition activates PERK-eIF2alpha and sensitizes cells to endoplasmic reticulum stress
-
24705811
-
Feng YX, Sokol ES, Del Vecchio CA, Sanduja S, Claessen JH, Proia TA, Jin DX, Reinhardt F, Ploegh HL, Wang Q, et al. Epithelial-to-mesenchymal transition activates PERK-eIF2alpha and sensitizes cells to endoplasmic reticulum stress. Cancer Discov 2014; 4:702-15; PMID:24705811; http://dx.doi.org/10.1158/2159-8290.CD-13-0945
-
(2014)
Cancer Discov
, vol.4
, pp. 702-715
-
-
Feng, Y.X.1
Sokol, E.S.2
Del Vecchio, C.A.3
Sanduja, S.4
Claessen, J.H.5
Proia, T.A.6
Jin, D.X.7
Reinhardt, F.8
Ploegh, H.L.9
Wang, Q.10
-
125
-
-
84885126229
-
Brefeldin a effectively inhibits cancer stem cell-like properties and MMP-9 activity in human colorectal cancer Colo 205 cells
-
23973996
-
Tseng CN, Huang CF, Cho CL, Chang HW, Huang CW, Chiu CC, Chang YF. Brefeldin a effectively inhibits cancer stem cell-like properties and MMP-9 activity in human colorectal cancer Colo 205 cells. Molecules 2013; 18:10242-53; PMID:23973996; http://dx.doi.org/10.3390/molecules180910242
-
(2013)
Molecules
, vol.18
, pp. 10242-10253
-
-
Tseng, C.N.1
Huang, C.F.2
Cho, C.L.3
Chang, H.W.4
Huang, C.W.5
Chiu, C.C.6
Chang, Y.F.7
-
126
-
-
34247131255
-
Hypericin photoactivation triggers down-regulation of matrix metalloproteinase-9 expression in well-differentiated human nasopharyngeal cancer cells
-
17385073,; PMID:,; ttp://dx.doi.org/
-
Du HY, Olivo M, Mahendran R, Huang Q, Shen HM, Ong CN, Bay BH. Hypericin photoactivation triggers down-regulation of matrix metalloproteinase-9 expression in well-differentiated human nasopharyngeal cancer cells. Cell Mol Life Sci 2007; 64:979-88; PMID:17385073; ttp://dx.doi.org/10.1007/s00018-007-7030-1
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 979-988
-
-
Du, H.Y.1
Olivo, M.2
Mahendran, R.3
Huang, Q.4
Shen, H.M.5
Ong, C.N.6
Bay, B.H.7
-
127
-
-
84902969251
-
Epithelial-mesenchymal transition enhances response to oncolytic herpesviral therapy through nectin-1
-
24568312
-
Chen CH, Chen WY, Lin SF, Wong RJ. Epithelial-mesenchymal transition enhances response to oncolytic herpesviral therapy through nectin-1. Human Gene Therapy 2014; 25:539-51; PMID:24568312; http://dx.doi.org/10.1089/hum.2013.177
-
(2014)
Human Gene Therapy
, vol.25
, pp. 539-551
-
-
Chen, C.H.1
Chen, W.Y.2
Lin, S.F.3
Wong, R.J.4
-
128
-
-
40949086333
-
ER stress is associated with dedifferentiation and an epithelial-to-mesenchymal transition-like phenotype in PC Cl3 thyroid cells
-
18211961
-
Ulianich L, Garbi C, Treglia AS, Punzi D, Miele C, Raciti GA, Beguinot F, Consiglio E, Di Jeso B. ER stress is associated with dedifferentiation and an epithelial-to-mesenchymal transition-like phenotype in PC Cl3 thyroid cells. J Cell Sci 2008; 121:477-86; PMID:18211961; http://dx.doi.org/10.1242/jcs.017202
-
(2008)
J Cell Sci
, vol.121
, pp. 477-486
-
-
Ulianich, L.1
Garbi, C.2
Treglia, A.S.3
Punzi, D.4
Miele, C.5
Raciti, G.A.6
Beguinot, F.7
Consiglio, E.8
Di Jeso, B.9
-
129
-
-
84901150182
-
Endoplasmic reticulum stress induces epithelial-mesenchymal transition through autophagy via activation of c-src kinase
-
24863135
-
Moon SY, Kim HS, Nho KW, Jang YJ, Lee SK. Endoplasmic reticulum stress induces epithelial-mesenchymal transition through autophagy via activation of c-src kinase. Nephron Exp Nephrol 2014; 126:127-40; PMID:24863135; http://dx.doi.org/10.1159/000362457
-
(2014)
Nephron Exp Nephrol
, vol.126
, pp. 127-140
-
-
Moon, S.Y.1
Kim, H.S.2
Nho, K.W.3
Jang, Y.J.4
Lee, S.K.5
-
130
-
-
80052540057
-
Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein
-
21169555
-
Zhong Q, Zhou B, Ann DK, Minoo P, Liu Y, Banfalvi A, Krishnaveni MS, Dubourd M, Demaio L, Willis BC, et al. Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein. Am J Respir Cell Mol Biol 2011; 45:498-509; PMID:21169555; http://dx.doi.org/10.1165/rcmb.2010-0347OC
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 498-509
-
-
Zhong, Q.1
Zhou, B.2
Ann, D.K.3
Minoo, P.4
Liu, Y.5
Banfalvi, A.6
Krishnaveni, M.S.7
Dubourd, M.8
Demaio, L.9
Willis, B.C.10
-
131
-
-
84866440474
-
Suppression of tunicamycin-induced CD44v6 ectodomain shedding and apoptosis is correlated with temporal expression patterns of active ADAM10, MMP-9 and MMP-13 proteins in Caki-2 renal carcinoma cells
-
22923171,; PMID
-
Kim YH, Jung JC. Suppression of tunicamycin-induced CD44v6 ectodomain shedding and apoptosis is correlated with temporal expression patterns of active ADAM10, MMP-9 and MMP-13 proteins in Caki-2 renal carcinoma cells. Oncol Rep 2012; 28:1869-74; PMID:22923171
-
(2012)
Oncol Rep
, vol.28
, pp. 1869-1874
-
-
Kim, Y.H.1
Jung, J.C.2
-
132
-
-
84901286029
-
Melatonin inhibits endoplasmic reticulum stress and epithelial-mesenchymal transition during bleomycin-induced pulmonary fibrosis in mice
-
Zhao H, Wu QQ, Cao LF, Qing HY, Zhang C, Chen YH, Wang H, Liu RR, Xu DX. Melatonin inhibits endoplasmic reticulum stress and epithelial-mesenchymal transition during bleomycin-induced pulmonary fibrosis in mice. PLoS One 2014; 9:e97266
-
(2014)
PLoS One
, vol.9
-
-
Zhao, H.1
Wu, Q.Q.2
Cao, L.F.3
Qing, H.Y.4
Zhang, C.5
Chen, Y.H.6
Wang, H.7
Liu, R.R.8
Xu, D.X.9
-
133
-
-
84869085026
-
Vaccinia virus-mediated intra-tumoral expression of matrix metalloproteinase 9 enhances oncolysis of PC-3 xenograft tumors
-
22917220
-
Schafer S, Weibel S, Donat U, Zhang Q, Aguilar RJ, Chen NG, Szalay AA. Vaccinia virus-mediated intra-tumoral expression of matrix metalloproteinase 9 enhances oncolysis of PC-3 xenograft tumors. BMC Cancer 2012; 12:366; PMID:22917220; http://dx.doi.org/10.1186/1471-2407-12-366
-
(2012)
BMC Cancer
, vol.12
, pp. 366
-
-
Schafer, S.1
Weibel, S.2
Donat, U.3
Zhang, Q.4
Aguilar, R.J.5
Chen, N.G.6
Szalay, A.A.7
-
134
-
-
77958001733
-
Ectopic matrix metalloproteinase-9 expression in human brain tumor cells enhances oncolytic HSV vector infection
-
20463757
-
Hong CS, Fellows W, Niranjan A, Alber S, Watkins S, Cohen JB, Glorioso JC, Grandi P. Ectopic matrix metalloproteinase-9 expression in human brain tumor cells enhances oncolytic HSV vector infection. Gene Ther 2010; 17:1200-5; PMID:20463757; http://dx.doi.org/10.1038/gt.2010.66
-
(2010)
Gene Ther
, vol.17
, pp. 1200-1205
-
-
Hong, C.S.1
Fellows, W.2
Niranjan, A.3
Alber, S.4
Watkins, S.5
Cohen, J.B.6
Glorioso, J.C.7
Grandi, P.8
-
135
-
-
39449135326
-
Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors
-
18281493
-
Mahller YY, Vaikunth SS, Ripberger MC, Baird WH, Saeki Y, Cancelas JA, Crombleholme TM, Cripe TP. Tissue inhibitor of metalloproteinase-3 via oncolytic herpesvirus inhibits tumor growth and vascular progenitors. Cancer Res 2008; 68:1170-9; PMID:18281493; http://dx.doi.org/10.1158/0008-5472.CAN-07-2734
-
(2008)
Cancer Res
, vol.68
, pp. 1170-1179
-
-
Mahller, Y.Y.1
Vaikunth, S.S.2
Ripberger, M.C.3
Baird, W.H.4
Saeki, Y.5
Cancelas, J.A.6
Crombleholme, T.M.7
Cripe, T.P.8
-
136
-
-
79952845160
-
ER stress modulates cellular metabolism
-
21241252
-
Wang X, Eno CO, Altman BJ, Zhu Y, Zhao G, Olberding KE, Rathmell JC, Li C. ER stress modulates cellular metabolism. Biochem J 2011; 435:285-96; PMID:21241252; http://dx.doi.org/10.1042/BJ20101864
-
(2011)
Biochem J
, vol.435
, pp. 285-296
-
-
Wang, X.1
Eno, C.O.2
Altman, B.J.3
Zhu, Y.4
Zhao, G.5
Olberding, K.E.6
Rathmell, J.C.7
Li, C.8
-
137
-
-
78049307002
-
De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation
-
20876798, Van
-
Rysman E, Brusselmans K, Scheys K, Timmermans L, Derua R, Munck S, Van Veldhoven PP, Waltregny D, Daniels VW, Machiels J, et al. De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation. Cancer Res 2010; 70:8117-26; PMID:20876798; http://dx.doi.org/10.1158/0008-5472.CAN-09-3871
-
(2010)
Cancer Res
, vol.70
, pp. 8117-8126
-
-
Rysman, E.1
Brusselmans, K.2
Scheys, K.3
Timmermans, L.4
Derua, R.5
Munck, S.6
Veldhoven, P.P.7
Waltregny, D.8
Daniels, V.W.9
Machiels, J.10
-
138
-
-
77955281020
-
Glutamine addiction: a new therapeutic target in cancer
-
20570523
-
Wise DR, Thompson CB. Glutamine addiction: a new therapeutic target in cancer. Trends Biochem Sci 2010; 35:427-33; PMID:20570523; http://dx.doi.org/10.1016/j.tibs.2010.05.003
-
(2010)
Trends Biochem Sci
, vol.35
, pp. 427-433
-
-
Wise, D.R.1
Thompson, C.B.2
-
139
-
-
61849135453
-
Tumor suppressors and cell metabolism: a recipe for cancer growth
-
19270154
-
Jones RG, Thompson CB. Tumor suppressors and cell metabolism: a recipe for cancer growth. Genes Dev 2009; 23:537-48; PMID:19270154; http://dx.doi.org/10.1101/gad.1756509
-
(2009)
Genes Dev
, vol.23
, pp. 537-548
-
-
Jones, R.G.1
Thompson, C.B.2
-
140
-
-
84899714318
-
Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2alpha
-
24648524
-
Guan BJ, Krokowski D, Majumder M, Schmotzer CL, Kimball SR, Merrick WC, Koromilas AE, Hatzoglou M. Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2alpha. J Biol Chem 2014; 289:12593-611; PMID:24648524; http://dx.doi.org/10.1074/jbc.M113.543215
-
(2014)
J Biol Chem
, vol.289
, pp. 12593-12611
-
-
Guan, B.J.1
Krokowski, D.2
Majumder, M.3
Schmotzer, C.L.4
Kimball, S.R.5
Merrick, W.C.6
Koromilas, A.E.7
Hatzoglou, M.8
-
142
-
-
84894057014
-
Prolonged endoplasmic reticulum stress alters placental morphology and causes low birth weight
-
24370435
-
Kawakami T, Yoshimi M, Kadota Y, Inoue M, Sato M, Suzuki S. Prolonged endoplasmic reticulum stress alters placental morphology and causes low birth weight. Toxicol Appl Pharmacol 2014; 275:134-44; PMID:24370435; http://dx.doi.org/10.1016/j.taap.2013.12.008
-
(2014)
Toxicol Appl Pharmacol
, vol.275
, pp. 134-144
-
-
Kawakami, T.1
Yoshimi, M.2
Kadota, Y.3
Inoue, M.4
Sato, M.5
Suzuki, S.6
-
143
-
-
84901946068
-
O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway
-
24857547
-
Ferrer CM, Lynch TP, Sodi VL, Falcone JN, Schwab LP, Peacock DL, Vocadlo DJ, Seagroves TN, Reginato MJ. O-GlcNAcylation regulates cancer metabolism and survival stress signaling via regulation of the HIF-1 pathway. Mol Cell 2014; 54:820-31; PMID:24857547; http://dx.doi.org/10.1016/j.molcel.2014.04.026
-
(2014)
Mol Cell
, vol.54
, pp. 820-831
-
-
Ferrer, C.M.1
Lynch, T.P.2
Sodi, V.L.3
Falcone, J.N.4
Schwab, L.P.5
Peacock, D.L.6
Vocadlo, D.J.7
Seagroves, T.N.8
Reginato, M.J.9
-
144
-
-
84905851428
-
Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availability
-
24973213
-
Mendez-Lucas A, Hyrossova P, Novellasdemunt L, Vinals F, Perales JC. Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availability. J Biol Chem 2014; 289:22090-102; PMID:24973213; http://dx.doi.org/10.1074/jbc.M114.566927
-
(2014)
J Biol Chem
, vol.289
, pp. 22090-22102
-
-
Mendez-Lucas, A.1
Hyrossova, P.2
Novellasdemunt, L.3
Vinals, F.4
Perales, J.C.5
-
145
-
-
77950346282
-
Immunity, inflammation, and cancer
-
20303878
-
Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010; 140:883-99; PMID:20303878; http://dx.doi.org/10.1016/j.cell.2010.01.025
-
(2010)
Cell
, vol.140
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
146
-
-
79952996039
-
Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage
-
21339211
-
Grivennikov SI, Karin M. Inflammatory cytokines in cancer: tumour necrosis factor and interleukin 6 take the stage. Ann Rheum Dis 2011; 70 Suppl 1:i104-8; PMID:21339211; http://dx.doi.org/10.1136/ard.2010.140145
-
(2011)
Ann Rheum Dis
, vol.70 Suppl 1
, pp. i104-i8
-
-
Grivennikov, S.I.1
Karin, M.2
-
147
-
-
84908665169
-
ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development
-
25132496
-
Nakagawa H, Umemura A, Taniguchi K, Font-Burgada J, Dhar D, Ogata H, Zhong Z, Valasek MA, Seki E, Hidalgo J, et al. ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. Cancer cell 2014; 26:331-43; PMID:25132496; http://dx.doi.org/10.1016/j.ccr.2014.07.001
-
(2014)
Cancer cell
, vol.26
, pp. 331-343
-
-
Nakagawa, H.1
Umemura, A.2
Taniguchi, K.3
Font-Burgada, J.4
Dhar, D.5
Ogata, H.6
Zhong, Z.7
Valasek, M.A.8
Seki, E.9
Hidalgo, J.10
-
148
-
-
79955632933
-
Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells
-
21464300
-
Mahadevan NR, Rodvold J, Sepulveda H, Rossi S, Drew AF, Zanetti M. Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells. Proc Natl Acad Sci U S A 2011; 108:6561-6; PMID:21464300; http://dx.doi.org/10.1073/pnas.1008942108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 6561-6566
-
-
Mahadevan, N.R.1
Rodvold, J.2
Sepulveda, H.3
Rossi, S.4
Drew, A.F.5
Zanetti, M.6
-
149
-
-
79952283465
-
How to improve the immunogenicity of chemotherapy and radiotherapy
-
21298323
-
Ma Y, Conforti R, Aymeric L, Locher C, Kepp O, Kroemer G, Zitvogel L. How to improve the immunogenicity of chemotherapy and radiotherapy. Cancer Metastasis Rev 2011; 30:71-82; PMID:21298323; http://dx.doi.org/10.1007/s10555-011-9283-2
-
(2011)
Cancer Metastasis Rev
, vol.30
, pp. 71-82
-
-
Ma, Y.1
Conforti, R.2
Aymeric, L.3
Locher, C.4
Kepp, O.5
Kroemer, G.6
Zitvogel, L.7
-
150
-
-
77950366886
-
Decoding cell death signals in inflammation and immunity
-
20303871
-
Zitvogel L, Kepp O, Kroemer G. Decoding cell death signals in inflammation and immunity. Cell 2010; 140:798-804; PMID:20303871; http://dx.doi.org/10.1016/j.cell.2010.02.015
-
(2010)
Cell
, vol.140
, pp. 798-804
-
-
Zitvogel, L.1
Kepp, O.2
Kroemer, G.3
-
151
-
-
70350569295
-
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
-
19767732
-
Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med 2009; 15:1170-8; PMID:19767732; http://dx.doi.org/10.1038/nm.2028
-
(2009)
Nat Med
, vol.15
, pp. 1170-1178
-
-
Ghiringhelli, F.1
Apetoh, L.2
Tesniere, A.3
Aymeric, L.4
Ma, Y.5
Ortiz, C.6
Vermaelen, K.7
Panaretakis, T.8
Mignot, G.9
Ullrich, E.10
-
152
-
-
84887445500
-
Calreticulin surface exposure is abrogated in cells lacking, chaperone-mediated autophagy-essential gene, LAMP2A
-
24091669
-
Garg AD, Dudek AM, Agostinis P. Calreticulin surface exposure is abrogated in cells lacking, chaperone-mediated autophagy-essential gene, LAMP2A. Cell Death Dis 2013; 4:e826; PMID:24091669; http://dx.doi.org/10.1038/cddis.2013.372
-
(2013)
Cell Death Dis
, vol.4
, pp. e826
-
-
Garg, A.D.1
Dudek, A.M.2
Agostinis, P.3
-
153
-
-
83755181759
-
Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice
-
22174255
-
Michaud M, Martins I, Sukkurwala AQ, Adjemian S, Ma Y, Pellegatti P, Shen S, Kepp O, Scoazec M, Mignot G, et al. Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice. Science 2011; 334:1573-7; PMID:22174255; http://dx.doi.org/10.1126/science.1208347
-
(2011)
Science
, vol.334
, pp. 1573-1577
-
-
Michaud, M.1
Martins, I.2
Sukkurwala, A.Q.3
Adjemian, S.4
Ma, Y.5
Pellegatti, P.6
Shen, S.7
Kepp, O.8
Scoazec, M.9
Mignot, G.10
-
154
-
-
84874192617
-
T-helper-1-cell cytokines drive cancer into senescence
-
23376950
-
Braumuller H, Wieder T, Brenner E, Assmann S, Hahn M, Alkhaled M, Schilbach K, Essmann F, Kneilling M, Griessinger C, et al. T-helper-1-cell cytokines drive cancer into senescence. Nature 2013; 494:361-5; PMID:23376950; http://dx.doi.org/10.1038/nature11824
-
(2013)
Nature
, vol.494
, pp. 361-365
-
-
Braumuller, H.1
Wieder, T.2
Brenner, E.3
Assmann, S.4
Hahn, M.5
Alkhaled, M.6
Schilbach, K.7
Essmann, F.8
Kneilling, M.9
Griessinger, C.10
-
155
-
-
84890034987
-
Danger signalling during cancer cell death: origins, plasticity and regulation
-
23686135
-
Garg AD, Martin S, Golab J, Agostinis P. Danger signalling during cancer cell death: origins, plasticity and regulation. Cell Death Differ 2014; 21:26-38; PMID:23686135; http://dx.doi.org/10.1038/cdd.2013.48
-
(2014)
Cell Death Differ
, vol.21
, pp. 26-38
-
-
Garg, A.D.1
Martin, S.2
Golab, J.3
Agostinis, P.4
-
156
-
-
84881032285
-
GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy
-
23887632
-
Firczuk M, Gabrysiak M, Barankiewicz J, Domagala A, Nowis D, Kujawa M, Jankowska-Steifer E, Wachowska M, Glodkowska-Mrowka E, Korsak B, et al. GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy. Cell Death Dis 2013; 4:e741; PMID:23887632; http://dx.doi.org/10.1038/cddis.2013.265
-
(2013)
Cell Death Dis
, vol.4
, pp. e741
-
-
Firczuk, M.1
Gabrysiak, M.2
Barankiewicz, J.3
Domagala, A.4
Nowis, D.5
Kujawa, M.6
Jankowska-Steifer, E.7
Wachowska, M.8
Glodkowska-Mrowka, E.9
Korsak, B.10
-
157
-
-
84885720059
-
Trial watch: Oncolytic viruses for cancer therapy
-
23894720
-
Vacchelli E, Eggermont A, Sautes-Fridman C, Galon J, Zitvogel L, Kroemer G, Galluzzi L. Trial watch: Oncolytic viruses for cancer therapy. Oncoimmunology 2013; 2:e24612; PMID:23894720; http://dx.doi.org/10.4161/onci.24612
-
(2013)
Oncoimmunology
, vol.2
, pp. e24612
-
-
Vacchelli, E.1
Eggermont, A.2
Sautes-Fridman, C.3
Galon, J.4
Zitvogel, L.5
Kroemer, G.6
Galluzzi, L.7
-
158
-
-
84896394053
-
Protein disulfide isomerase: a promising target for cancer therapy
-
24184531
-
Xu S, Sankar S, Neamati N. Protein disulfide isomerase: a promising target for cancer therapy. Drug Discov Today 2014; 19:222-40; PMID:24184531; http://dx.doi.org/10.1016/j.drudis.2013.10.017
-
(2014)
Drug Discov Today
, vol.19
, pp. 222-240
-
-
Xu, S.1
Sankar, S.2
Neamati, N.3
-
159
-
-
80051580475
-
Photodynamic therapy of cancer: an update
-
21617154
-
Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO, Hahn SM, Hamblin MR, Juzeniene A, Kessel D, et al. Photodynamic therapy of cancer: an update. CA Cancer J Clin 2011; 61:250-81; PMID:21617154; http://dx.doi.org/10.3322/caac.20114
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 250-281
-
-
Agostinis, P.1
Berg, K.2
Cengel, K.A.3
Foster, T.H.4
Girotti, A.W.5
Gollnick, S.O.6
Hahn, S.M.7
Hamblin, M.R.8
Juzeniene, A.9
Kessel, D.10
-
160
-
-
78651064011
-
Future directions in castrate-resistant prostate cancer therapy
-
21208854
-
Antonarakis ES, Carducci MA. Future directions in castrate-resistant prostate cancer therapy. Clin Genitourin Cancer 2010; 8:37-46; PMID:21208854; http://dx.doi.org/10.3816/CGC.2010.n.006
-
(2010)
Clin Genitourin Cancer
, vol.8
, pp. 37-46
-
-
Antonarakis, E.S.1
Carducci, M.A.2
-
162
-
-
4444302042
-
Effect on tumor cells of blocking survival response to glucose deprivation
-
15339968
-
Park HR, Tomida A, Sato S, Tsukumo Y, Yun J, Yamori T, Hayakawa Y, Tsuruo T, Shin-ya K. Effect on tumor cells of blocking survival response to glucose deprivation. J Natl Cancer Inst 2004; 96:1300-10; PMID:15339968; http://dx.doi.org/10.1093/jnci/djh243
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 1300-1310
-
-
Park, H.R.1
Tomida, A.2
Sato, S.3
Tsukumo, Y.4
Yun, J.5
Yamori, T.6
Hayakawa, Y.7
Tsuruo, T.8
Shin-ya, K.9
-
163
-
-
84876666017
-
Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKbeta leading to autophagy
-
23500541
-
Xi H, Barredo JC, Merchan JR, Lampidis TJ. Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKbeta leading to autophagy. Biochem Pharmacol 2013; 85:1463-77; PMID:23500541; http://dx.doi.org/10.1016/j.bcp.2013.02.037
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 1463-1477
-
-
Xi, H.1
Barredo, J.C.2
Merchan, J.R.3
Lampidis, T.J.4
-
164
-
-
81255203382
-
Induction of immunogenic apoptosis by blockade of epidermal growth factor receptor activation with a specific antibody
-
21984704
-
Garrido G, Rabasa A, Sanchez B, Lopez MV, Blanco R, Lopez A, Hernandez DR, Perez R, Fernandez LE. Induction of immunogenic apoptosis by blockade of epidermal growth factor receptor activation with a specific antibody. J Immunol 2011; 187:4954-66; PMID:21984704; http://dx.doi.org/10.4049/jimmunol.1003477
-
(2011)
J Immunol
, vol.187
, pp. 4954-4966
-
-
Garrido, G.1
Rabasa, A.2
Sanchez, B.3
Lopez, M.V.4
Blanco, R.5
Lopez, A.6
Hernandez, D.R.7
Perez, R.8
Fernandez, L.E.9
-
165
-
-
41549145181
-
Immunogenicity of anthracyclines: moving towards more personalized medicine
-
18353726
-
Apetoh L, Mignot G, Panaretakis T, Kroemer G, Zitvogel L. Immunogenicity of anthracyclines: moving towards more personalized medicine. Trends Mol Med 2008; 14:141-51; PMID:18353726; http://dx.doi.org/10.1016/j.molmed.2008.02.002
-
(2008)
Trends Mol Med
, vol.14
, pp. 141-151
-
-
Apetoh, L.1
Mignot, G.2
Panaretakis, T.3
Kroemer, G.4
Zitvogel, L.5
-
167
-
-
79956366646
-
Proteasome inhibitors in cancer therapy
-
21484190
-
Crawford LJ, Walker B, Irvine AE. Proteasome inhibitors in cancer therapy. J Cell Commun Signal 2011; 5:101-10; PMID:21484190; http://dx.doi.org/10.1007/s12079-011-0121-7
-
(2011)
J Cell Commun Signal
, vol.5
, pp. 101-110
-
-
Crawford, L.J.1
Walker, B.2
Irvine, A.E.3
-
168
-
-
84873399856
-
Vemurafenib potently induces endoplasmic reticulum stress-mediated apoptosis in BRAFV600E melanoma cells
-
23362240
-
Beck D, Niessner H, Smalley KS, Flaherty K, Paraiso KH, Busch C, Sinnberg T, Vasseur S, Iovanna JL, Driessen S, et al. Vemurafenib potently induces endoplasmic reticulum stress-mediated apoptosis in BRAFV600E melanoma cells. Sci Signal 2013; 6:ra7; PMID:23362240; http://dx.doi.org/10.1126/scisignal.2003057
-
(2013)
Sci Signal
, vol.6
, pp. ra7
-
-
Beck, D.1
Niessner, H.2
Smalley, K.S.3
Flaherty, K.4
Paraiso, K.H.5
Busch, C.6
Sinnberg, T.7
Vasseur, S.8
Iovanna, J.L.9
Driessen, S.10
-
169
-
-
33745929641
-
A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme
-
16804518
-
Guzman M, Duarte MJ, Blazquez C, Ravina J, Rosa MC, Galve-Roperh I, Sanchez C, Velasco G, Gonzalez-Feria L. A pilot clinical study of Delta9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. Br J Cancer 2006; 95:197-203; PMID:16804518; http://dx.doi.org/10.1038/sj.bjc.6603236
-
(2006)
Br J Cancer
, vol.95
, pp. 197-203
-
-
Guzman, M.1
Duarte, M.J.2
Blazquez, C.3
Ravina, J.4
Rosa, M.C.5
Galve-Roperh, I.6
Sanchez, C.7
Velasco, G.8
Gonzalez-Feria, L.9
-
170
-
-
84884526075
-
Endoplasmic reticulum stress is involved in the response of human laryngeal carcinoma cells to Carboplatin but is absent in Carboplatin-resistant cells
-
24086737
-
Brozovic A, Vukovic L, Polancac DS, Arany I, Koberle B, Fritz G, Fiket Z, Majhen D, Ambriovic-Ristov A, Osmak M. Endoplasmic reticulum stress is involved in the response of human laryngeal carcinoma cells to Carboplatin but is absent in Carboplatin-resistant cells. PLoS One 2013; 8:e76397; PMID:24086737; http://dx.doi.org/10.1371/journal.pone.0076397
-
(2013)
PLoS One
, vol.8
-
-
Brozovic, A.1
Vukovic, L.2
Polancac, D.S.3
Arany, I.4
Koberle, B.5
Fritz, G.6
Fiket, Z.7
Majhen, D.8
Ambriovic-Ristov, A.9
Osmak, M.10
-
171
-
-
84876131792
-
Anticancer activity of cardiac glycosides: At the frontier between cell-autonomous and immunological effects
-
23264921
-
Kepp O, Menger L, Vacchelli E, Adjemian S, Martins I, Ma Y, Sukkurwala AQ, Michaud M, Galluzzi L, Zitvogel L, et al. Anticancer activity of cardiac glycosides: At the frontier between cell-autonomous and immunological effects. Oncoimmunology 2012; 1:1640-2; PMID:23264921; http://dx.doi.org/10.4161/onci.21684
-
(2012)
Oncoimmunology
, vol.1
, pp. 1640-1642
-
-
Kepp, O.1
Menger, L.2
Vacchelli, E.3
Adjemian, S.4
Martins, I.5
Ma, Y.6
Sukkurwala, A.Q.7
Michaud, M.8
Galluzzi, L.9
Zitvogel, L.10
-
172
-
-
38849191201
-
Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib
-
18245486
-
Kardosh A, Golden EB, Pyrko P, Uddin J, Hofman FM, Chen TC, Louie SG, Petasis NA, Schonthal AH. Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib. Cancer Res 2008; 68:843-51; PMID:18245486; http://dx.doi.org/10.1158/0008-5472.CAN-07-5555
-
(2008)
Cancer Res
, vol.68
, pp. 843-851
-
-
Kardosh, A.1
Golden, E.B.2
Pyrko, P.3
Uddin, J.4
Hofman, F.M.5
Chen, T.C.6
Louie, S.G.7
Petasis, N.A.8
Schonthal, A.H.9
-
173
-
-
79955763984
-
Targeting sarcoplasmic/endoplasmic reticulum Ca(2)+-ATPase 2 by curcumin induces ER stress-associated apoptosis for treating human liposarcoma
-
21282356
-
Wang L, Song R, Shen Y, Sun Y, Gu Y, Shu Y, Xu Q. Targeting sarcoplasmic/endoplasmic reticulum Ca(2)+-ATPase 2 by curcumin induces ER stress-associated apoptosis for treating human liposarcoma. Mol Cancer Ther 2011; 10:461-71; PMID:21282356; http://dx.doi.org/10.1158/1535-7163.MCT-10-0812
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 461-471
-
-
Wang, L.1
Song, R.2
Shen, Y.3
Sun, Y.4
Gu, Y.5
Shu, Y.6
Xu, Q.7
-
174
-
-
79952025567
-
Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment
-
22069551
-
Teiten MH, Eifes S, Dicato M, Diederich M. Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment. Toxins (Basel) 2010; 2:128-62; PMID:22069551; http://dx.doi.org/10.3390/toxins2010128
-
(2010)
Toxins (Basel)
, vol.2
, pp. 128-162
-
-
Teiten, M.H.1
Eifes, S.2
Dicato, M.3
Diederich, M.4
-
175
-
-
70350786392
-
Cyclophosphamide and cancer: golden anniversary
-
19786984
-
Emadi A, Jones RJ, Brodsky RA. Cyclophosphamide and cancer: golden anniversary. Nat Rev Clin Oncol 2009; 6:638-47; PMID:19786984; http://dx.doi.org/10.1038/nrclinonc.2009.146
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 638-647
-
-
Emadi, A.1
Jones, R.J.2
Brodsky, R.A.3
-
176
-
-
84892397621
-
Synergistic cytotoxicity of gemcitabine, clofarabine and edelfosine in lymphoma cell lines
-
24413065,; PMID
-
Valdez BC, Zander AR, Song G, Murray D, Nieto Y, Li Y, Champlin RE, Andersson BS. Synergistic cytotoxicity of gemcitabine, clofarabine and edelfosine in lymphoma cell lines. Blood Cancer J 2014; 4:e171; PMID:24413065
-
(2014)
Blood Cancer J
, vol.4
, pp. e171
-
-
Valdez, B.C.1
Zander, A.R.2
Song, G.3
Murray, D.4
Nieto, Y.5
Li, Y.6
Champlin, R.E.7
Andersson, B.S.8
-
177
-
-
84883196231
-
Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death
-
23892893
-
Magnaghi P, D'Alessio R, Valsasina B, Avanzi N, Rizzi S, Asa D, Gasparri F, Cozzi L, Cucchi U, Orrenius C, et al. Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death. Nat Chem Biol 2013; 9:548-56; PMID:23892893; http://dx.doi.org/10.1038/nchembio.1313
-
(2013)
Nat Chem Biol
, vol.9
, pp. 548-556
-
-
Magnaghi, P.1
D'Alessio, R.2
Valsasina, B.3
Avanzi, N.4
Rizzi, S.5
Asa, D.6
Gasparri, F.7
Cozzi, L.8
Cucchi, U.9
Orrenius, C.10
-
178
-
-
34547122494
-
HDAC inhibitors: clinical update and mechanism-based potential
-
17498667
-
Glaser KB. HDAC inhibitors: clinical update and mechanism-based potential. Biochem Pharmacol 2007; 74:659-71; PMID:17498667; http://dx.doi.org/10.1016/j.bcp.2007.04.007
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 659-671
-
-
Glaser, K.B.1
-
179
-
-
73949147271
-
Activation of the unfolded protein response contributes toward the antitumor activity of vorinostat
-
20072656,; PMID
-
Kahali S, Sarcar B, Fang B, Williams ES, Koomen JM, Tofilon PJ, Chinnaiyan P. Activation of the unfolded protein response contributes toward the antitumor activity of vorinostat. Neoplasia 2010; 12:80-6; PMID:20072656
-
(2010)
Neoplasia
, vol.12
, pp. 80-86
-
-
Kahali, S.1
Sarcar, B.2
Fang, B.3
Williams, E.S.4
Koomen, J.M.5
Tofilon, P.J.6
Chinnaiyan, P.7
-
180
-
-
84902543448
-
High hydrostatic pressure induces immunogenic cell death in human tumor cells
-
24500981
-
Fucikova J, Moserova I, Truxova I, Hermanova I, Vancurova I, Partlova S, Fialova A, Sojka L, Cartron PF, Houska M, et al. High hydrostatic pressure induces immunogenic cell death in human tumor cells. Int J Cancer 2014; 135:1165-77; PMID:24500981; http://dx.doi.org/10.1002/ijc.28766
-
(2014)
Int J Cancer
, vol.135
, pp. 1165-1177
-
-
Fucikova, J.1
Moserova, I.2
Truxova, I.3
Hermanova, I.4
Vancurova, I.5
Partlova, S.6
Fialova, A.7
Sojka, L.8
Cartron, P.F.9
Houska, M.10
-
181
-
-
84857039457
-
Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers
-
22062686
-
Jhaveri K, Taldone T, Modi S, Chiosis G. Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers. Biochim Biophys Acta 2012; 1823:742-55; PMID:22062686; http://dx.doi.org/10.1016/j.bbamcr.2011.10.008
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 742-755
-
-
Jhaveri, K.1
Taldone, T.2
Modi, S.3
Chiosis, G.4
-
182
-
-
42049090876
-
Effectiveness of regional chemotherapy with TNF-alpha/melphalan in advanced soft tissue sarcoma of the extremities
-
18392998
-
Taeger G, Grabellus F, Podleska LE, Muller S, Ruchholtz S. Effectiveness of regional chemotherapy with TNF-alpha/melphalan in advanced soft tissue sarcoma of the extremities. Int J Hyperthermia 2008; 24:193-203; PMID:18392998; http://dx.doi.org/10.1080/02656730701868387
-
(2008)
Int J Hyperthermia
, vol.24
, pp. 193-203
-
-
Taeger, G.1
Grabellus, F.2
Podleska, L.E.3
Muller, S.4
Ruchholtz, S.5
-
183
-
-
84877055352
-
Hyperthermic isolated liver perfusion with melphalan and bevacizumab
-
23182850,; PMID
-
Voron T, Zinzindohoue F, Journois D, Herve C, Ponzio O, Lucas N. Hyperthermic isolated liver perfusion with melphalan and bevacizumab. J Visc Surg 2013; 150:60-6; PMID:23182850
-
(2013)
J Visc Surg
, vol.150
, pp. 60-66
-
-
Voron, T.1
Zinzindohoue, F.2
Journois, D.3
Herve, C.4
Ponzio, O.5
Lucas, N.6
-
184
-
-
77955239765
-
Management of isolated nonresectable liver metastases in colorectal cancer patients: a case-control study of isolated hepatic perfusion with melphalan versus systemic chemotherapy
-
20110289
-
van Iersel LB, Koopman M, van de Velde CJ, Mol L, van Persijn van Meerten EL, Hartgrink HH, Kuppen PJ, Vahrmeijer AL, Nortier JW, Tollenaar RA, et al. Management of isolated nonresectable liver metastases in colorectal cancer patients: a case-control study of isolated hepatic perfusion with melphalan versus systemic chemotherapy. Ann Oncol 2010; 21:1662-7; PMID:20110289; http://dx.doi.org/10.1093/annonc/mdp589
-
(2010)
Ann Oncol
, vol.21
, pp. 1662-1667
-
-
van Iersel, L.B.1
Koopman, M.2
van de Velde, C.J.3
Mol, L.4
van Persijn van Meerten, E.L.5
Hartgrink, H.H.6
Kuppen, P.J.7
Vahrmeijer, A.L.8
Nortier, J.W.9
Tollenaar, R.A.10
-
185
-
-
0346333288
-
Hyperthermic isolated hepatic perfusion using melphalan for patients with ocular melanoma metastatic to liver
-
14695133,; PMID
-
Alexander HR, Jr., Libutti SK, Pingpank JF, Steinberg SM, Bartlett DL, Helsabeck C, Beresneva T. Hyperthermic isolated hepatic perfusion using melphalan for patients with ocular melanoma metastatic to liver. Clin Cancer Res 2003; 9:6343-9; PMID:14695133
-
(2003)
Clin Cancer Res
, vol.9
, pp. 6343-6349
-
-
Alexander, H.R.1
Libutti, S.K.2
Pingpank, J.F.3
Steinberg, S.M.4
Bartlett, D.L.5
Helsabeck, C.6
Beresneva, T.7
-
186
-
-
84904628230
-
Microtubules and their role in cellular stress in cancer
-
24995158
-
Parker AL, Kavallaris M, McCarroll JA. Microtubules and their role in cellular stress in cancer. Front Oncol 2014; 4:153; PMID:24995158; http://dx.doi.org/10.3389/fonc.2014.00153
-
(2014)
Front Oncol
, vol.4
, pp. 153
-
-
Parker, A.L.1
Kavallaris, M.2
McCarroll, J.A.3
-
187
-
-
77957374075
-
Microtubule-binding agents: a dynamic field of cancer therapeutics
-
20885410
-
Dumontet C, Jordan MA. Microtubule-binding agents: a dynamic field of cancer therapeutics. Nat Rev Drug Discov 2010; 9:790-803; PMID:20885410; http://dx.doi.org/10.1038/nrd3253
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 790-803
-
-
Dumontet, C.1
Jordan, M.A.2
-
188
-
-
84866769442
-
Oxaliplatin as part of adjuvant therapy for colon cancer: more complicated than once thought
-
22915653
-
Mayer RJ. Oxaliplatin as part of adjuvant therapy for colon cancer: more complicated than once thought. J Clin Oncol 2012; 30:3325-7; PMID:22915653; http://dx.doi.org/10.1200/JCO.2012.44.1949
-
(2012)
J Clin Oncol
, vol.30
, pp. 3325-3327
-
-
Mayer, R.J.1
-
189
-
-
84863264554
-
Cancer and radiation therapy: current advances and future directions
-
22408567
-
Baskar R, Lee KA, Yeo R, Yeoh KW. Cancer and radiation therapy: current advances and future directions. Int J Med Sci 2012; 9:193-9; PMID:22408567; http://dx.doi.org/10.7150/ijms.3635
-
(2012)
Int J Med Sci
, vol.9
, pp. 193-199
-
-
Baskar, R.1
Lee, K.A.2
Yeo, R.3
Yeoh, K.W.4
-
190
-
-
80054883247
-
Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2
-
21516121
-
Chen J, Xie J, Jiang Z, Wang B, Wang Y, Hu X. Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2. Oncogene 2011; 30:4297-306; PMID:21516121; http://dx.doi.org/10.1038/onc.2011.137
-
(2011)
Oncogene
, vol.30
, pp. 4297-4306
-
-
Chen, J.1
Xie, J.2
Jiang, Z.3
Wang, B.4
Wang, Y.5
Hu, X.6
-
191
-
-
33749238553
-
Discovery and development of sorafenib: a multikinase inhibitor for treating cancer
-
17016424
-
Wilhelm S, Carter C, Lynch M, Lowinger T, Dumas J, Smith RA, Schwartz B, Simantov R, Kelley S. Discovery and development of sorafenib: a multikinase inhibitor for treating cancer. Nat Rev Drug Discov 2006; 5:835-44; PMID:17016424; http://dx.doi.org/10.1038/nrd2130
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 835-844
-
-
Wilhelm, S.1
Carter, C.2
Lynch, M.3
Lowinger, T.4
Dumas, J.5
Smith, R.A.6
Schwartz, B.7
Simantov, R.8
Kelley, S.9
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