The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathway

Cancer Research

Volumn 72, Issue 20, 2012, Pages 5396-5406

  Wang, Yugang ^a   Alam, Goleeta N ^a   Ning, Yu ^a   Visioli, Fernanda ^a   Dong, Zhihong ^a   Nör, Jacques E ^a   Polverini, Peter J ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ANGIOGENESIS INHIBITOR; COMPLEMENTARY DNA; CXCL14 CHEMOKINE; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUCOSE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; PROTEIN PERK; PROTEIN TYROSINE KINASE; THROMBOSPONDIN 1; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REGULATOR GENE; SIGNAL TRANSDUCTION; TUMOR CELL; TUMOR GROWTH; UNFOLDED PROTEIN RESPONSE; UPREGULATION; VEGF GENE;

ACTIVATING TRANSCRIPTION FACTOR 4; CELL LINE, TUMOR; EIF-2 KINASE; HUMANS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; UNFOLDED PROTEIN RESPONSE;

EID: 84867562151     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-0474     Document Type: Article

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