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Volumn 21, Issue 1, 2014, Pages 26-38

Danger signalling during cancer cell death: Origins, plasticity and regulation

Author keywords

anti tumour immunity; cancer; DAMPs; danger signals; immunogenic cell death; immunogenicity; tumour immunology

Indexed keywords

BORTEZOMIB; CHAPERONE; CHEMOKINE RECEPTOR CXCR3; CYCLOPHOSPHAMIDE; DIGITOXIN; DIGOXIN; DOXORUBICIN; FLUOROURACIL; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR; GEMCITABINE; IDARUBICIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MITOXANTRONE; MYELOID DIFFERENTIATION FACTOR 88; OXALIPLATIN; PERFORIN; PROTEIN BAX; SHIKONIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR RECEPTOR; WOGONIN;

EID: 84890034987     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.48     Document Type: Review
Times cited : (190)

References (129)
  • 4
    • 84891738301 scopus 로고    scopus 로고
    • Cell death in the neighbourhood: Direct microenvironmental effects of apoptosis in normal and neoplastic tissues
    • Gregory CD, Pound JD. Cell death in the neighbourhood: Direct microenvironmental effects of apoptosis in normal and neoplastic tissues. J Pathol 2010; 223: 177-194.
    • (2010) J Pathol , vol.223 , pp. 177-194
    • Gregory, C.D.1    Pound, J.D.2
  • 7
    • 84857997683 scopus 로고    scopus 로고
    • A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
    • Garg AD, Krysko DV, Verfaillie T, Kaczmarek A, Ferreira GB, Marysael T et al. A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J 2012; 31: 1062-1079.
    • (2012) EMBO J , vol.31 , pp. 1062-1079
    • Garg, A.D.1    Krysko, D.V.2    Verfaillie, T.3    Kaczmarek, A.4    Ferreira, G.B.5    Marysael, T.6
  • 10
    • 84876098009 scopus 로고    scopus 로고
    • Targeting ER stress induced apoptosis and inflammation in cancer
    • Verfaillie T, Garg AD, Agostinis P. Targeting ER stress induced apoptosis and inflammation in cancer. Cancer Lett 2010; 332: 249-264.
    • (2010) Cancer Lett , vol.332 , pp. 249-264
    • Verfaillie, T.1    Garg, A.D.2    Agostinis, P.3
  • 14
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger P. Tolerance, danger, and the extended family. Annu Rev Immunol 1994; 12: 991-1045.
    • (1994) Annu Rev Immunol , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 16
    • 34948820602 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
    • Apetoh L, Ghiringhelli F, Tesniere A, Obeid M, Ortiz C, Criollo A et al. Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med 2007; 13: 1050-1059.
    • (2007) Nat Med , vol.13 , pp. 1050-1059
    • Apetoh, L.1    Ghiringhelli, F.2    Tesniere, A.3    Obeid, M.4    Ortiz, C.5    Criollo, A.6
  • 18
    • 0037072758 scopus 로고    scopus 로고
    • Differential acquisition of antigenic peptides by Hsp70 and Hsc70 under oxidative conditions
    • Callahan MK, Chaillot D, Jacquin C, Clark PR, Menoret A. Differential acquisition of antigenic peptides by Hsp70 and Hsc70 under oxidative conditions. J Biol Chem 2002; 277: 33604-33609.
    • (2002) J Biol Chem , vol.277 , pp. 33604-33609
    • Callahan, M.K.1    Chaillot, D.2    Jacquin, C.3    Clark, P.R.4    Menoret, A.5
  • 19
    • 51049094007 scopus 로고    scopus 로고
    • Oxidation of ovarian epithelial cancer cells by hypochlorous acid enhances immunogenicity and stimulates T cells that recognize autologous primary tumor
    • Chiang CL, Ledermann JA, Aitkens E, Benjamin E, Katz DR, Chain BM. Oxidation of ovarian epithelial cancer cells by hypochlorous acid enhances immunogenicity and stimulates T cells that recognize autologous primary tumor. Clin Cancer Res 2008; 14: 4898-4907.
    • (2008) Clin Cancer Res , vol.14 , pp. 4898-4907
    • Chiang, C.L.1    Ledermann, J.A.2    Aitkens, E.3    Benjamin, E.4    Katz, D.R.5    Chain, B.M.6
  • 21
    • 79251580687 scopus 로고    scopus 로고
    • Oxidation-specific epitopes are danger-Associated molecular patterns recognized by pattern recognition receptors of innate immunity
    • Miller YI, Choi SH, Wiesner P, Fang L, Harkewicz R, Hartvigsen K et al. Oxidation-specific epitopes are danger-Associated molecular patterns recognized by pattern recognition receptors of innate immunity. Circ Res 2011; 108: 235-248.
    • (2011) Circ Res , vol.108 , pp. 235-248
    • Miller, Y.I.1    Choi, S.H.2    Wiesner, P.3    Fang, L.4    Harkewicz, R.5    Hartvigsen, K.6
  • 22
    • 84856696459 scopus 로고    scopus 로고
    • Hypericin-based photodynamic therapy induces surface exposure of damage-Associated molecular patterns like HSP70 and calreticulin
    • Garg AD, Krysko DV, Vandenabeele P, Agostinis P. Hypericin-based photodynamic therapy induces surface exposure of damage-Associated molecular patterns like HSP70 and calreticulin. Cancer Immunol Immunother 2012; 61: 215-221.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 215-221
    • Garg, A.D.1    Krysko, D.V.2    Vandenabeele, P.3    Agostinis, P.4
  • 23
    • 84871218486 scopus 로고    scopus 로고
    • Wogonin induced calreticulin/ annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner
    • Yang Y, Li XJ, Chen Z, Zhu XX, Wang J, Zhang LB et al. Wogonin induced calreticulin/ annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner. PLoS One 2012; 7: E50811.
    • (2012) PLoS One , vol.7
    • Yang, Y.1    Li, X.J.2    Chen, Z.3    Zhu, X.X.4    Wang, J.5    Zhang, L.B.6
  • 24
    • 84864128654 scopus 로고    scopus 로고
    • Cardiac glycosides exert anticancer effects by inducing immunogenic cell death
    • 143ra99
    • Menger L, Vacchelli E, Adjemian S, Martins I, Ma Y, Shen S et al. Cardiac glycosides exert anticancer effects by inducing immunogenic cell death. Sci Transl Med 2012; 4: 143ra99.
    • (2012) Sci Transl Med , vol.4
    • Menger, L.1    Vacchelli, E.2    Adjemian, S.3    Martins, I.4    Ma, Y.5    Shen, S.6
  • 25
    • 84870984470 scopus 로고    scopus 로고
    • PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress
    • Verfaillie T, Rubio N, Garg AD, Bultynck G, Rizzuto R, Decuypere JP et al. PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress. Cell Death Differ 2012; 19: 1880-1891.
    • (2012) Cell Death Differ , vol.19 , pp. 1880-1891
    • Verfaillie, T.1    Rubio, N.2    Garg, A.D.3    Bultynck, G.4    Rizzuto, R.5    Decuypere, J.P.6
  • 26
    • 84861112821 scopus 로고    scopus 로고
    • Coxsackievirus B3 is an oncolytic virus with immunostimulatory properties that is active against lung adenocarcinoma
    • Miyamoto S, Inoue H, Nakamura T, Yamada M, Sakamoto C, Urata Y et al. Coxsackievirus B3 is an oncolytic virus with immunostimulatory properties that is active against lung adenocarcinoma. Cancer Res 2012; 72: 2609-2621.
    • (2012) Cancer Res , vol.72 , pp. 2609-2621
    • Miyamoto, S.1    Inoue, H.2    Nakamura, T.3    Yamada, M.4    Sakamoto, C.5    Urata, Y.6
  • 27
    • 33645142635 scopus 로고    scopus 로고
    • Viruses, endoplasmic reticulum stress, and interferon responses
    • He B. Viruses, endoplasmic reticulum stress, and interferon responses. Cell Death Differ 2006; 13: 393-403.
    • (2006) Cell Death Differ , vol.13 , pp. 393-403
    • He, B.1
  • 30
    • 77956927110 scopus 로고    scopus 로고
    • Photodynamic therapy: Illuminating the road from cell death towards anti-Tumour immunity
    • Garg AD, Nowis D, Golab J, Agostinis P. Photodynamic therapy: Illuminating the road from cell death towards anti-Tumour immunity. Apoptosis 2010; 15: 1050-1071.
    • (2010) Apoptosis , vol.15 , pp. 1050-1071
    • Garg, A.D.1    Nowis, D.2    Golab, J.3    Agostinis, P.4
  • 31
    • 80355147292 scopus 로고    scopus 로고
    • Type I interferon is selectively required by dendritic cells for immune rejection of tumors
    • Diamond MS, Kinder M, Matsushita H, Mashayekhi M, Dunn GP, Archambault JM et al. Type I interferon is selectively required by dendritic cells for immune rejection of tumors. J Exp Med 2011; 208: 1989-2003.
    • (2011) J Exp Med , vol.208 , pp. 1989-2003
    • Diamond, M.S.1    Kinder, M.2    Matsushita, H.3    Mashayekhi, M.4    Dunn, G.P.5    Archambault, J.M.6
  • 32
    • 80355136945 scopus 로고    scopus 로고
    • Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells
    • Fuertes MB, Kacha AK, Kline J, Woo SR, Kranz DM, Murphy KM et al. Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8{alpha}+ dendritic cells. J Exp Med 2011; 208: 2005-2016.
    • (2011) J Exp Med , vol.208 , pp. 2005-2016
    • Fuertes, M.B.1    Kacha, A.K.2    Kline, J.3    Woo, S.R.4    Kranz, D.M.5    Murphy, K.M.6
  • 33
    • 79955533004 scopus 로고    scopus 로고
    • Type I IFNs control antigen retention and survival of CD8alpha(+) dendritic cells after uptake of tumor apoptotic cells leading to cross-priming
    • Lorenzi S, Mattei F, Sistigu A, Bracci L, Spadaro F, Sanchez M et al. Type I IFNs control antigen retention and survival of CD8alpha(+) dendritic cells after uptake of tumor apoptotic cells leading to cross-priming. J Immunol 2011; 186: 5142-5150.
    • (2011) J Immunol , vol.186 , pp. 5142-5150
    • Lorenzi, S.1    Mattei, F.2    Sistigu, A.3    Bracci, L.4    Spadaro, F.5    Sanchez, M.6
  • 35
    • 34249650184 scopus 로고    scopus 로고
    • Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: Therapeutic implications
    • Spisek R, Charalambous A, Mazumder A, Vesole DH, Jagannath S, Dhodapkar MV. Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: Therapeutic implications. Blood 2007; 109: 4839-4845.
    • (2007) Blood , vol.109 , pp. 4839-4845
    • Spisek, R.1    Charalambous, A.2    Mazumder, A.3    Vesole, D.H.4    Jagannath, S.5    Dhodapkar, M.V.6
  • 36
    • 79952433556 scopus 로고    scopus 로고
    • A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion
    • Gopal U, Bohonowych JE, Lema-Tome C, Liu A, Garrett-Mayer E, Wang B et al. A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion. PLoS One 2011; 6: E17649.
    • (2011) PLoS One , vol.6
    • Gopal, U.1    Bohonowych, J.E.2    Lema-Tome, C.3    Liu, A.4    Garrett-Mayer, E.5    Wang, B.6
  • 37
    • 26844468253 scopus 로고    scopus 로고
    • Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-Activation of LRP on the phagocyte
    • Gardai SJ, McPhillips KA, Frasch SC, Janssen WJ, Starefeldt A, Murphy-Ullrich JE et al. Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-Activation of LRP on the phagocyte. Cell 2005; 123: 321-334.
    • (2005) Cell , vol.123 , pp. 321-334
    • Gardai, S.J.1    McPhillips, K.A.2    Frasch, S.C.3    Janssen, W.J.4    Starefeldt, A.5    Murphy-Ullrich, J.E.6
  • 38
    • 84855712718 scopus 로고    scopus 로고
    • CD91-dependent programming of T-helper cell responses following heat shock protein immunization
    • Pawaria S, Binder RJ. CD91-dependent programming of T-helper cell responses following heat shock protein immunization. Nat Commun 2011; 2: 521.
    • (2011) Nat Commun , vol.2 , pp. 521
    • Pawaria, S.1    Binder, R.J.2
  • 39
    • 78549275158 scopus 로고    scopus 로고
    • Improved clinical outcome in indolent B-cell lymphoma patients vaccinated with autologous tumor cells experiencing immunogenic death
    • Zappasodi R, Pupa SM, Ghedini GC, Bongarzone I, Magni M, Cabras AD et al. Improved clinical outcome in indolent B-cell lymphoma patients vaccinated with autologous tumor cells experiencing immunogenic death. Cancer Res 2010; 70: 9062-9072.
    • (2010) Cancer Res , vol.70 , pp. 9062-9072
    • Zappasodi, R.1    Pupa, S.M.2    Ghedini, G.C.3    Bongarzone, I.4    Magni, M.5    Cabras, A.D.6
  • 40
    • 84872099178 scopus 로고    scopus 로고
    • PDT-induced HSP70 externalization up-regulates NO production via TLR2 signal pathway in macrophages
    • Song S, Zhou F, Chen WR, Xing D. PDT-induced HSP70 externalization up-regulates NO production via TLR2 signal pathway in macrophages. FEBS Lett 2012; 587: 128-135.
    • (2012) FEBS Lett , vol.587 , pp. 128-135
    • Song, S.1    Zhou, F.2    Chen, W.R.3    Xing, D.4
  • 41
    • 79960406242 scopus 로고    scopus 로고
    • Human tumor cells killed by anthracyclines induce a tumor-specific immune response
    • Fucikova J, Kralikova P, Fialova A, Brtnicky T, Rob L, Bartunkova J et al. Human tumor cells killed by anthracyclines induce a tumor-specific immune response. Cancer Res 2011; 71: 4821-4833.
    • (2011) Cancer Res , vol.71 , pp. 4821-4833
    • Fucikova, J.1    Kralikova, P.2    Fialova, A.3    Brtnicky, T.4    Rob, L.5    Bartunkova, J.6
  • 42
    • 70249090374 scopus 로고    scopus 로고
    • Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
    • Elliott MR, Chekeni FB, Trampont PC, Lazarowski ER, Kadl A, Walk SF et al. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 2009; 461: 282-286.
    • (2009) Nature , vol.461 , pp. 282-286
    • Elliott, M.R.1    Chekeni, F.B.2    Trampont, P.C.3    Lazarowski, E.R.4    Kadl, A.5    Walk, S.F.6
  • 44
    • 70350569295 scopus 로고    scopus 로고
    • Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
    • Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med 2009; 15: 1170-1178.
    • (2009) Nat Med , vol.15 , pp. 1170-1178
    • Ghiringhelli, F.1    Apetoh, L.2    Tesniere, A.3    Aymeric, L.4    Ma, Y.5    Ortiz, C.6
  • 45
    • 83755181759 scopus 로고    scopus 로고
    • Autophagydependent anticancer immune responses induced by chemotherapeutic agents in mice
    • Michaud M, Martins I, Sukkurwala AQ, Adjemian S, Ma Y, Pellegatti P et al. Autophagydependent anticancer immune responses induced by chemotherapeutic agents in mice. Science 2011; 334: 1573-1577.
    • (2011) Science , vol.334 , pp. 1573-1577
    • Michaud, M.1    Martins, I.2    Sukkurwala, A.Q.3    Adjemian, S.4    Ma, Y.5    Pellegatti, P.6
  • 46
    • 84865422909 scopus 로고    scopus 로고
    • Tumorinfiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1
    • Chiba S, Baghdadi M, Akiba H, Yoshiyama H, Kinoshita I, Dosaka-Akita H et al. Tumorinfiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1. Nat Immunol 2012; 13: 832-842.
    • (2012) Nat Immunol , vol.13 , pp. 832-842
    • Chiba, S.1    Baghdadi, M.2    Akiba, H.3    Yoshiyama, H.4    Kinoshita, I.5    Dosaka-Akita, H.6
  • 47
    • 38949206309 scopus 로고    scopus 로고
    • The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity
    • Behrens MD, Wagner WM, Krco CJ, Erskine CL, Kalli KR, Krempski J et al. The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity. Blood 2008; 111: 1472-1479.
    • (2008) Blood , vol.111 , pp. 1472-1479
    • Behrens, M.D.1    Wagner, W.M.2    Krco, C.J.3    Erskine, C.L.4    Kalli, K.R.5    Krempski, J.6
  • 48
    • 32944468985 scopus 로고    scopus 로고
    • Gout-Associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-Associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440: 237-241.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 50
    • 79953068336 scopus 로고    scopus 로고
    • Emerging role of damage-Associated molecular patterns derived from mitochondria in inflammation
    • Krysko DV, Agostinis P, Krysko O, Garg AD, Bachert C, Lambrecht BN et al. Emerging role of damage-Associated molecular patterns derived from mitochondria in inflammation. Trends Immunol 2011; 32: 157-164.
    • (2011) Trends Immunol , vol.32 , pp. 157-164
    • Krysko, D.V.1    Agostinis, P.2    Krysko, O.3    Garg, A.D.4    Bachert, C.5    Lambrecht, B.N.6
  • 51
    • 84863599924 scopus 로고    scopus 로고
    • Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma
    • Jube S, Rivera Z, Bianchi ME, Powers A, Wang E, Pagano IS et al. Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesothelioma. Cancer Res 2012; 72: 3290-3301.
    • (2012) Cancer Res , vol.72 , pp. 3290-3301
    • Jube, S.1    Rivera, Z.2    Bianchi, M.E.3    Powers, A.4    Wang, E.5    Pagano, I.S.6
  • 52
    • 0842266582 scopus 로고    scopus 로고
    • Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation
    • Palumbo R, Sampaolesi M, De Marchis F, Tonlorenzi R, Colombetti S, Mondino A et al. Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation. J Cell Biol 2004; 164: 441-449.
    • (2004) J Cell Biol , vol.164 , pp. 441-449
    • Palumbo, R.1    Sampaolesi, M.2    De Marchis, F.3    Tonlorenzi, R.4    Colombetti, S.5    Mondino, A.6
  • 53
    • 84863173852 scopus 로고    scopus 로고
    • High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharideinduced immune responses
    • Yang D, Postnikov YV, Li Y, Tewary P, de la Rosa G, Wei F et al. High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharideinduced immune responses. J Exp Med 2012; 209: 157-171.
    • (2012) J Exp Med , vol.209 , pp. 157-171
    • Yang, D.1    Postnikov, Y.V.2    Li, Y.3    Tewary, P.4    De La Rosa, G.5    Wei, F.6
  • 54
    • 77249085646 scopus 로고    scopus 로고
    • Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation
    • Cohen I, Rider P, Carmi Y, Braiman A, Dotan S, White MR et al. Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proc Natl Acad Sci USA 2010; 107: 2574-2579.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2574-2579
    • Cohen, I.1    Rider, P.2    Carmi, Y.3    Braiman, A.4    Dotan, S.5    White, M.R.6
  • 57
    • 84859240988 scopus 로고    scopus 로고
    • In vitro studies on erythrosinebased photodynamic therapy of malignant and pre-malignant oral epithelial cells
    • Garg AD, Bose M, Ahmed MI, Bonass WA, Wood SR. In vitro studies on erythrosinebased photodynamic therapy of malignant and pre-malignant oral epithelial cells. PLoS One 2012; 7: E34475.
    • (2012) PLoS One , vol.7
    • Garg, A.D.1    Bose, M.2    Ahmed, M.I.3    Bonass, W.A.4    Wood, S.R.5
  • 58
    • 84866183414 scopus 로고    scopus 로고
    • Immune mechanism of the antitumor effects generated by bortezomib
    • Chang CL, Hsu YT, Wu CC, Yang YC, Wang C, Wu TC et al. Immune mechanism of the antitumor effects generated by bortezomib. J Immunol 2012; 189: 3209-3220.
    • (2012) J Immunol , vol.189 , pp. 3209-3220
    • Chang, C.L.1    Hsu, Y.T.2    Wu, C.C.3    Yang, Y.C.4    Wang, C.5    Wu, T.C.6
  • 59
    • 8644224931 scopus 로고    scopus 로고
    • Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR
    • Baltzis D, Qu LK, Papadopoulou S, Blais JD, Bell JC, Sonenberg N et al. Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR. J Virol 2004; 78: 12747-12761.
    • (2004) J Virol , vol.78 , pp. 12747-12761
    • Baltzis, D.1    Qu, L.K.2    Papadopoulou, S.3    Blais, J.D.4    Bell, J.C.5    Sonenberg, N.6
  • 60
    • 0037333913 scopus 로고    scopus 로고
    • Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK.
    • Pavio N, Romano PR, Graczyk TM, Feinstone SM, Taylor DR. Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK. J Virol 2003; 77: 3578-3585.
    • (2003) J Virol , vol.77 , pp. 3578-3585
    • Pavio, N.1    Romano, P.R.2    Graczyk, T.M.3    Feinstone, S.M.4    Taylor, D.R.5
  • 61
    • 48849096740 scopus 로고    scopus 로고
    • The eIF2alpha kinases inhibit vesicular stomatitis virus replication independently of eIF2alpha phosphorylation
    • Krishnamoorthy J, Mounir Z, Raven JF, Koromilas AE. The eIF2alpha kinases inhibit vesicular stomatitis virus replication independently of eIF2alpha phosphorylation. Cell Cycle 2008; 7: 2346-2351.
    • (2008) Cell Cycle , vol.7 , pp. 2346-2351
    • Krishnamoorthy, J.1    Mounir, Z.2    Raven, J.F.3    Koromilas, A.E.4
  • 62
    • 33947386301 scopus 로고    scopus 로고
    • After shrinkage apoptotic cells expose internal membrane-derived epitopes on their plasma membranes
    • Franz S, Herrmann K, Furnrohr BG, Sheriff A, Frey B, Gaipl US et al. After shrinkage apoptotic cells expose internal membrane-derived epitopes on their plasma membranes. Cell Death Differ 2007; 14: 733-742.
    • (2007) Cell Death Differ , vol.14 , pp. 733-742
    • Franz, S.1    Herrmann, K.2    Furnrohr, B.G.3    Sheriff, A.4    Frey, B.5    Gaipl, U.S.6
  • 63
    • 77957942834 scopus 로고    scopus 로고
    • Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis
    • Chekeni FB, Elliott MR, Sandilos JK, Walk SF, Kinchen JM, Lazarowski ER et al. Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis. Nature 2010; 467: 863-867.
    • (2010) Nature , vol.467 , pp. 863-867
    • Chekeni, F.B.1    Elliott, M.R.2    Sandilos, J.K.3    Walk, S.F.4    Kinchen, J.M.5    Lazarowski, E.R.6
  • 64
  • 65
    • 1342303482 scopus 로고    scopus 로고
    • Of mice and not men: Differences between mouse and human immunology
    • Mestas J, Hughes CC. Of mice and not men: Differences between mouse and human immunology. J Immunol 2004; 172: 2731-2738.
    • (2004) J Immunol , vol.172 , pp. 2731-2738
    • Mestas, J.1    Hughes, C.C.2
  • 67
    • 79952716229 scopus 로고    scopus 로고
    • Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy
    • Ma Y, Aymeric L, Locher C, Mattarollo SR, Delahaye NF, Pereira P et al. Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. J Exp Med 2011; 208: 491-503.
    • (2011) J Exp Med , vol.208 , pp. 491-503
    • Ma, Y.1    Aymeric, L.2    Locher, C.3    Mattarollo, S.R.4    Delahaye, N.F.5    Pereira, P.6
  • 68
    • 0025923025 scopus 로고
    • Human TH1 and TH2 subsets: Doubt no more
    • Romagnani S. Human TH1 and TH2 subsets: Doubt no more. Immunol Today 1991; 12: 256-257.
    • (1991) Immunol Today , vol.12 , pp. 256-257
    • Romagnani, S.1
  • 70
    • 0027204621 scopus 로고
    • Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production
    • Del Prete G, De Carli M, Almerigogna F, Giudizi MG, Biagiotti R, Romagnani S. Human IL-10 is produced by both type 1 helper (Th1) and type 2 helper (Th2) T cell clones and inhibits their antigen-specific proliferation and cytokine production. J Immunol 1993; 150: 353-360.
    • (1993) J Immunol , vol.150 , pp. 353-360
    • Del Prete, G.1    De Carli, M.2    Almerigogna, F.3    Giudizi, M.G.4    Biagiotti, R.5    Romagnani, S.6
  • 71
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 2012; 12: 252-264.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 73
    • 84860852600 scopus 로고    scopus 로고
    • Blocking IDO activity to enhance anti-Tumor immunity
    • Munn DH. Blocking IDO activity to enhance anti-Tumor immunity. Front Biosci (Elite Ed) 2012; 4: 734-745.
    • (2012) Front Biosci (Elite Ed) , vol.4 , pp. 734-745
    • Munn, D.H.1
  • 77
    • 2542464918 scopus 로고
    • Phenol red in tissue culture media is a weak estrogen: Implications concerning the study of estrogen-responsive cells in culture
    • Berthois Y, Katzenellenbogen JA, Katzenellenbogen BS. Phenol red in tissue culture media is a weak estrogen: Implications concerning the study of estrogen-responsive cells in culture. Proc Natl Acad Sci USA 1986; 83: 2496-2500.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2496-2500
    • Berthois, Y.1    Katzenellenbogen, J.A.2    Katzenellenbogen, B.S.3
  • 79
    • 40549084310 scopus 로고    scopus 로고
    • Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: Relation to common inflammatory diseases?
    • Verma D, Lerm M, Blomgran Julinder R, Eriksson P, Soderkvist P, Sarndahl E. Gene polymorphisms in the NALP3 inflammasome are associated with interleukin-1 production and severe inflammation: Relation to common inflammatory diseases? Arthritis Rheum 2008; 58: 888-894.
    • (2008) Arthritis Rheum , vol.58 , pp. 888-894
    • Verma, D.1    Lerm, M.2    Blomgran Julinder, R.3    Eriksson, P.4    Soderkvist, P.5    Sarndahl, E.6
  • 80
    • 84859877626 scopus 로고    scopus 로고
    • The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1beta and IL-18 production
    • Verma D, Sarndahl E, Andersson H, Eriksson P, Fredrikson M, Jonsson JI et al. The Q705K polymorphism in NLRP3 is a gain-of-function alteration leading to excessive interleukin-1beta and IL-18 production. PLoS One 2012; 7: E34977.
    • (2012) PLoS One , vol.7
    • Verma, D.1    Sarndahl, E.2    Andersson, H.3    Eriksson, P.4    Fredrikson, M.5    Jonsson, J.I.6
  • 81
    • 84862068459 scopus 로고    scopus 로고
    • Genetic variation in Toll-like receptors and disease susceptibility
    • Netea MG, Wijmenga C, O'Neill LA. Genetic variation in Toll-like receptors and disease susceptibility. Nat Immunol 2012; 13: 535-542.
    • (2012) Nat Immunol , vol.13 , pp. 535-542
    • Netea, M.G.1    Wijmenga, C.2    O'Neill, L.A.3
  • 82
    • 70350569295 scopus 로고    scopus 로고
    • Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
    • Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C et al. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med 2009; 15: 1170-1178.
    • (2009) Nat Med , vol.15 , pp. 1170-1178
    • Ghiringhelli, F.1    Apetoh, L.2    Tesniere, A.3    Aymeric, L.4    Ma, Y.5    Ortiz, C.6
  • 84
    • 84860361435 scopus 로고    scopus 로고
    • HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4
    • Schiraldi M, Raucci A, Munoz LM, Livoti E, Celona B, Venereau E et al. HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4. J Exp Med 2012; 209: 551-563.
    • (2012) J Exp Med , vol.209 , pp. 551-563
    • Schiraldi, M.1    Raucci, A.2    Munoz, L.M.3    Livoti, E.4    Celona, B.5    Venereau, E.6
  • 85
    • 84862648897 scopus 로고    scopus 로고
    • Damage associated molecular pattern molecule-induced microRNAs (DAMPmiRs) in human peripheral blood mononuclear cells
    • Unlu S, Tang S, Wang E, Martinez I, Tang D, Bianchi ME et al. Damage associated molecular pattern molecule-induced microRNAs (DAMPmiRs) in human peripheral blood mononuclear cells. PLoS One 2012; 7: E38899.
    • (2012) PLoS One , vol.7
    • Unlu, S.1    Tang, S.2    Wang, E.3    Martinez, I.4    Tang, D.5    Bianchi, M.E.6
  • 86
    • 79952192382 scopus 로고    scopus 로고
    • Immune cell regulation by autocrine purinergic signalling
    • Junger WG. Immune cell regulation by autocrine purinergic signalling. Nat Rev Immunol 2011; 11: 201-212.
    • (2011) Nat Rev Immunol , vol.11 , pp. 201-212
    • Junger, W.G.1
  • 88
    • 84865511926 scopus 로고    scopus 로고
    • Novel role of PKR in inflammasome activation and HMGB1 release
    • Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundback P et al. Novel role of PKR in inflammasome activation and HMGB1 release. Nature 2012; 488: 670-674.
    • (2012) Nature , vol.488 , pp. 670-674
    • Lu, B.1    Nakamura, T.2    Inouye, K.3    Li, J.4    Tang, Y.5    Lundback, P.6
  • 89
    • 0034698830 scopus 로고    scopus 로고
    • High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes
    • Andersson U, Wang H, Palmblad K, Aveberger AC, Bloom O, Erlandsson-Harris H et al. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 2000; 192: 565-570.
    • (2000) J Exp Med , vol.192 , pp. 565-570
    • Andersson, U.1    Wang, H.2    Palmblad, K.3    Aveberger, A.C.4    Bloom, O.5    Erlandsson-Harris, H.6
  • 90
    • 84872530748 scopus 로고    scopus 로고
    • Tissue damage-Associated ''danger signals'' influence T-cell responses that promote the progression of preneoplasia to cancer
    • He Y, Zha J, Wang Y, Liu W, Yang X, Yu P. Tissue damage-Associated ''danger signals'' influence T-cell responses that promote the progression of preneoplasia to cancer. Cancer Res 2013; 73: 629-639.
    • (2013) Cancer Res , vol.73 , pp. 629-639
    • He, Y.1    Zha, J.2    Wang, Y.3    Liu, W.4    Yang, X.5    Yu, P.6
  • 91
    • 84872086179 scopus 로고    scopus 로고
    • Chemotherapy-Triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
    • Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F et al. Chemotherapy-Triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth. Nat Med 2013; 19: 57-64.
    • (2013) Nat Med , vol.19 , pp. 57-64
    • Bruchard, M.1    Mignot, G.2    Derangere, V.3    Chalmin, F.4    Chevriaux, A.5    Vegran, F.6
  • 92
    • 43249109372 scopus 로고    scopus 로고
    • Isolation and characterization of exosomes from cell culture supernatants and biological fluids
    • Chapter 3(Unit 3)
    • Thery C, Amigorena S, Raposo G, Clayton A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protoc Cell Biol 2006; Chapter 3(Unit 3): 22.
    • (2006) Curr Protoc Cell Biol , vol.22
    • Thery, C.1    Amigorena, S.2    Raposo, G.3    Clayton, A.4
  • 93
    • 0033767690 scopus 로고    scopus 로고
    • Exosome: From internal vesicle of the multivesicular body to intercellular signaling device
    • Denzer K, Kleijmeer MJ, Heijnen HF, Stoorvogel W, Geuze HJ. Exosome: From internal vesicle of the multivesicular body to intercellular signaling device. J Cell Sci 2000; 113(Pt 19): 3365-3374.
    • (2000) J Cell Sci , vol.113 , Issue.PART 19 , pp. 3365-3374
    • Denzer, K.1    Kleijmeer, M.J.2    Heijnen, H.F.3    Stoorvogel, W.4    Geuze, H.J.5
  • 94
    • 0036676445 scopus 로고    scopus 로고
    • Exosomes: Composition, biogenesis and function
    • Thery C, Zitvogel L, Amigorena S. Exosomes: Composition, biogenesis and function. Nat Rev Immunol 2002; 2: 569-579.
    • (2002) Nat Rev Immunol , vol.2 , pp. 569-579
    • Thery, C.1    Zitvogel, L.2    Amigorena, S.3
  • 95
    • 57049103401 scopus 로고    scopus 로고
    • Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers
    • Skog J, Wurdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol 2008; 10: 1470-1476.
    • (2008) Nat Cell Biol , vol.10 , pp. 1470-1476
    • Skog, J.1    Wurdinger, T.2    Van Rijn, S.3    Meijer, D.H.4    Gainche, L.5    Sena-Esteves, M.6
  • 96
    • 76749106591 scopus 로고    scopus 로고
    • Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation
    • Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M et al. Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation. Cancer Res 2010; 70: 1668-1678.
    • (2010) Cancer Res , vol.70 , pp. 1668-1678
    • Nazarenko, I.1    Rana, S.2    Baumann, A.3    McAlear, J.4    Hellwig, A.5    Trendelenburg, M.6
  • 99
    • 0037141153 scopus 로고    scopus 로고
    • Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles
    • Andreola G, Rivoltini L, Castelli C, Huber V, Perego P, Deho P et al. Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. J Exp Med 2002; 195: 1303-1316.
    • (2002) J Exp Med , vol.195 , pp. 1303-1316
    • Andreola, G.1    Rivoltini, L.2    Castelli, C.3    Huber, V.4    Perego, P.5    Deho, P.6
  • 102
    • 79960516623 scopus 로고    scopus 로고
    • Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production
    • Clayton A, Al-Taei S, Webber J, Mason MD, Tabi Z. Cancer exosomes express CD39 and CD73, which suppress T cells through adenosine production. J Immunol 2011; 187: 676-683.
    • (2011) J Immunol , vol.187 , pp. 676-683
    • Clayton, A.1    Al-Taei, S.2    Webber, J.3    Mason, M.D.4    Tabi, Z.5
  • 103
    • 34250351459 scopus 로고    scopus 로고
    • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
    • Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A et al. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 2007; 204: 1257-1265.
    • (2007) J Exp Med , vol.204 , pp. 1257-1265
    • Deaglio, S.1    Dwyer, K.M.2    Gao, W.3    Friedman, D.4    Usheva, A.5    Erat, A.6
  • 104
    • 79952070774 scopus 로고    scopus 로고
    • The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts
    • Peinado H, Lavotshkin S, Lyden D. The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts. Semin Cancer Biol 2011; 21: 139-146.
    • (2011) Semin Cancer Biol , vol.21 , pp. 139-146
    • Peinado, H.1    Lavotshkin, S.2    Lyden, D.3
  • 105
    • 84862736306 scopus 로고    scopus 로고
    • Metastasis. Exosomes drive premetastatic niche formation
    • Alderton GK. Metastasis. Exosomes drive premetastatic niche formation. Nat Rev Cancer 2012; 12: 447.
    • (2012) Nat Rev Cancer , vol.12 , pp. 447
    • Alderton, G.K.1
  • 106
    • 38449103605 scopus 로고    scopus 로고
    • The heat shock protein HSP70 promotes mouse NK cell activity against tumors that express inducible NKG2D ligands
    • Elsner L, Muppala V, Gehrmann M, Lozano J, Malzahn D, Bickeboller H et al. The heat shock protein HSP70 promotes mouse NK cell activity against tumors that express inducible NKG2D ligands. J Immunol 2007; 179: 5523-5533.
    • (2007) J Immunol , vol.179 , pp. 5523-5533
    • Elsner, L.1    Muppala, V.2    Gehrmann, M.3    Lozano, J.4    Malzahn, D.5    Bickeboller, H.6
  • 107
    • 38949191397 scopus 로고    scopus 로고
    • Exosomal transfer of proteins and RNAs at synapses in the nervous system
    • Smalheiser NR. Exosomal transfer of proteins and RNAs at synapses in the nervous system. Biol Direct 2007; 2: 35.
    • (2007) Biol Direct , vol.2 , pp. 35
    • Smalheiser, N.R.1
  • 108
    • 11344280957 scopus 로고    scopus 로고
    • Extracellular roles for the molecular chaperone, hsp90
    • Eustace BK, Jay DG. Extracellular roles for the molecular chaperone, hsp90. Cell Cycle 2004; 3: 1098-1100.
    • (2004) Cell Cycle , vol.3 , pp. 1098-1100
    • Eustace, B.K.1    Jay, D.G.2
  • 109
    • 33646369952 scopus 로고    scopus 로고
    • Immunostimulatory functions of membrane-bound and exported heat shock protein 70
    • Radons J, Multhoff G. Immunostimulatory functions of membrane-bound and exported heat shock protein 70. Exerc Immunol Rev 2005; 11: 17-33.
    • (2005) Exerc Immunol Rev , vol.11 , pp. 17-33
    • Radons, J.1    Multhoff, G.2
  • 110
    • 20244373139 scopus 로고    scopus 로고
    • Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming
    • Wolfers J, Lozier A, Raposo G, Regnault A, Thery C, Masurier C et al. Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming. Nat Med 2001; 7: 297-303.
    • (2001) Nat Med , vol.7 , pp. 297-303
    • Wolfers, J.1    Lozier, A.2    Raposo, G.3    Regnault, A.4    Thery, C.5    Masurier, C.6
  • 111
    • 33744928376 scopus 로고    scopus 로고
    • A membrane form of TNF-Alpha presented by exosomes delays T cell activation-induced cell death
    • Zhang HG, Liu C, Su K, Yu S, Zhang L, Zhang S et al. A membrane form of TNF-Alpha presented by exosomes delays T cell activation-induced cell death. J Immunol 2006; 176: 7385-7393.
    • (2006) J Immunol , vol.176 , pp. 7385-7393
    • Zhang, H.G.1    Liu, C.2    Su, K.3    Yu, S.4    Zhang, L.5    Zhang, S.6
  • 112
    • 84875065899 scopus 로고    scopus 로고
    • IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling
    • Lazear HM, Lancaster A, Wilkins C, Suthar MS, Huang A, Vick SC et al. IRF-3, IRF-5, and IRF-7 coordinately regulate the type I IFN response in myeloid dendritic cells downstream of MAVS signaling. PLoS Pathog 2013; 9: E1003118.
    • (2013) PLoS Pathog , vol.9
    • Lazear, H.M.1    Lancaster, A.2    Wilkins, C.3    Suthar, M.S.4    Huang, A.5    Vick, S.C.6
  • 113
    • 0038608016 scopus 로고    scopus 로고
    • Virus-induced heterodimer formation between IRF-5 and IRF-7 modulates assembly of the IFNA enhanceosome in vivo and transcriptional activity of IFNA genes
    • Barnes BJ, Field AE, Pitha-Rowe PM. Virus-induced heterodimer formation between IRF-5 and IRF-7 modulates assembly of the IFNA enhanceosome in vivo and transcriptional activity of IFNA genes. J Biol Chem 2003; 278: 16630-16641.
    • (2003) J Biol Chem , vol.278 , pp. 16630-16641
    • Barnes, B.J.1    Field, A.E.2    Pitha-Rowe, P.M.3
  • 114
    • 0034327172 scopus 로고    scopus 로고
    • Cutting edge: Selective IL-18 requirements for induction of compartmental IFN-gamma responses during viral infection
    • Pien GC, Satoskar AR, Takeda K, Akira S, Biron CA. Cutting edge: Selective IL-18 requirements for induction of compartmental IFN-gamma responses during viral infection. J Immunol 2000; 165: 4787-4791.
    • (2000) J Immunol , vol.165 , pp. 4787-4791
    • Pien, G.C.1    Satoskar, A.R.2    Takeda, K.3    Akira, S.4    Biron, C.A.5
  • 115
    • 33947417049 scopus 로고    scopus 로고
    • Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice
    • Szretter KJ, Gangappa S, Lu X, Smith C, Shieh WJ, Zaki SR et al. Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice. J Virol 2007; 81: 2736-2744.
    • (2007) J Virol , vol.81 , pp. 2736-2744
    • Szretter, K.J.1    Gangappa, S.2    Lu, X.3    Smith, C.4    Shieh, W.J.5    Zaki, S.R.6
  • 116
    • 81255203382 scopus 로고    scopus 로고
    • Induction of immunogenic apoptosis by blockade of epidermal growth factor receptor activation with a specific antibody
    • Garrido G, Rabasa A, Sanchez B, Lopez MV, Blanco R, Lopez A et al. Induction of immunogenic apoptosis by blockade of epidermal growth factor receptor activation with a specific antibody. J Immunol 2011; 187: 4954-4966.
    • (2011) J Immunol , vol.187 , pp. 4954-4966
    • Garrido, G.1    Rabasa, A.2    Sanchez, B.3    Lopez, M.V.4    Blanco, R.5    Lopez, A.6
  • 117
    • 84857879286 scopus 로고    scopus 로고
    • Primary effusion lymphoma cell death induced by bortezomib and AG 490 activates dendritic cells through CD91
    • Cirone M, Di Renzo L, Lotti LV, Conte V, Trivedi P, Santarelli R et al. Primary effusion lymphoma cell death induced by bortezomib and AG 490 activates dendritic cells through CD91. PLoS One 2012; 7: E31732.
    • (2012) PLoS One , vol.7
    • Cirone, M.1    Di Renzo, L.2    Lotti, L.V.3    Conte, V.4    Trivedi, P.5    Santarelli, R.6
  • 118
    • 79551523389 scopus 로고    scopus 로고
    • Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis
    • Schiavoni G, Sistigu A, Valentini M, Mattei F, Sestili P, Spadaro F et al. Cyclophosphamide synergizes with type I interferons through systemic dendritic cell reactivation and induction of immunogenic tumor apoptosis. Cancer Res 2011; 71: 768-778.
    • (2011) Cancer Res , vol.71 , pp. 768-778
    • Schiavoni, G.1    Sistigu, A.2    Valentini, M.3    Mattei, F.4    Sestili, P.5    Spadaro, F.6
  • 119
    • 79851509740 scopus 로고    scopus 로고
    • Viral-mediated oncolysis is the most critical factor in the late-phase of the tumor regression process upon vaccinia virus infection
    • Weibel S, Raab V, Yu YA, Worschech A, Wang E, Marincola FM et al. Viral-mediated oncolysis is the most critical factor in the late-phase of the tumor regression process upon vaccinia virus infection. BMC Cancer 2011; 11: 68.
    • (2011) BMC Cancer , vol.11 , pp. 68
    • Weibel, S.1    Raab, V.2    Yu, Y.A.3    Worschech, A.4    Wang, E.5    Marincola, F.M.6
  • 120
    • 80054764086 scopus 로고    scopus 로고
    • Virus-Tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-Triggered caspase-2 cell death
    • Mahoney DJ, Lefebvre C, Allan K, Brun J, Sanaei CA, Baird S et al. Virus-Tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-Triggered caspase-2 cell death. Cancer Cell 2011; 20: 443-456.
    • (2011) Cancer Cell , vol.20 , pp. 443-456
    • Mahoney, D.J.1    Lefebvre, C.2    Allan, K.3    Brun, J.4    Sanaei, C.A.5    Baird, S.6
  • 122
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J. The inflammasomes. Cell 2010; 140: 821-832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 123
    • 55149094300 scopus 로고    scopus 로고
    • Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells
    • Koenen HJ, Smeets RL, Vink PM, van Rijssen E, Boots AM, Joosten I. Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells. Blood 2008; 112: 2340-2352.
    • (2008) Blood , vol.112 , pp. 2340-2352
    • Koenen, H.J.1    Smeets, R.L.2    Vink, P.M.3    Van Rijssen, E.4    Boots, A.M.5    Joosten, I.6
  • 124
    • 0033952703 scopus 로고    scopus 로고
    • Tlr4: Central component of the sole mammalian LPS sensor
    • Beutler B. Tlr4: Central component of the sole mammalian LPS sensor. Curr Opin Immunol 2000; 12: 20-26.
    • (2000) Curr Opin Immunol , vol.12 , pp. 20-26
    • Beutler, B.1
  • 125
    • 70350339068 scopus 로고    scopus 로고
    • Mammalian P2-7 receptor pharmacology: Comparison of recombinant mouse, rat and human P2-7 receptors
    • Donnelly-Roberts DL, Namovic MT, Han P, Jarvis MF. Mammalian P2-7 receptor pharmacology: Comparison of recombinant mouse, rat and human P2-7 receptors. Br J Pharmacol 2009; 157: 1203-1214.
    • (2009) Br J Pharmacol , vol.157 , pp. 1203-1214
    • Donnelly-Roberts, D.L.1    Namovic, M.T.2    Han, P.3    Jarvis, M.F.4
  • 126
    • 78650413562 scopus 로고    scopus 로고
    • Differential regulation of human and murine P-selectin expression and function in vivo
    • Liu Z, Miner JJ, Yago T, Yao L, Lupu F, Xia L et al. Differential regulation of human and murine P-selectin expression and function in vivo. J Exp Med 2010; 207: 2975-2987.
    • (2010) J Exp Med , vol.207 , pp. 2975-2987
    • Liu, Z.1    Miner, J.J.2    Yago, T.3    Yao, L.4    Lupu, F.5    Xia, L.6
  • 127
    • 69849100452 scopus 로고    scopus 로고
    • Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner
    • Lima LG, Chammas R, Monteiro RQ, Moreira ME, Barcinski MA. Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner. Cancer Lett 2009; 283: 168-175.
    • (2009) Cancer Lett , vol.283 , pp. 168-175
    • Lima, L.G.1    Chammas, R.2    Monteiro, R.Q.3    Moreira, M.E.4    Barcinski, M.A.5
  • 129
    • 79960113933 scopus 로고    scopus 로고
    • A downside to apoptosis in cancer therapy?
    • Connell PP, Weichselbaum RR. A downside to apoptosis in cancer therapy? Nat Med 2011; 17: 780-782.
    • (2011) Nat Med , vol.17 , pp. 780-782
    • Connell, P.P.1    Weichselbaum, R.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.