Phosphorylation of Bcl-2 in G 2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis

Journal of Biological Chemistry

Volumn 277, Issue 40, 2002, Pages 37718-37731

  Vantieghem, Annelies ^a   Xu, Yan ^b,c   Assefa, Zerihun ^d   Piette, Jacques ^a   Vandenheede, Jackie R ^c   Merlevede, Wilfried ^d   De Witte, Peter A M ^a   Agostinis, Patrizia ^d,e  

^a Faculty of Medicine   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

^d FNRS   (Belgium)

^e Division of Biochemistry   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

PHASE-ARRESTED CELLS; PHOSPHORYLATION;

ASSAYS; CELLS; DEGRADATION; ENZYME INHIBITION; PHOTODYNAMIC THERAPY; PHOTOSENSITIVITY; PRECIPITATION (CHEMICAL); PROTEINS; TUMORS;

BIOCHEMISTRY;

ALANINE; ALPHA TUBULIN; CASPASE 3; CYCLIN B1; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLOHEXIMIDE; HYPERICIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOTOSENSITIZING AGENT; PROTEIN BCL 2; PROTEIN KINASE C; ROSCOVITINE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

APOPTOSIS; ARTICLE; CELL CYCLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; GENE OVEREXPRESSION; HELA CELL; HUMAN; HUMAN CELL; KINETICS; MICROTUBULE; MITOSIS SPINDLE; PHOSPHORYLATION; PHOTOACTIVATION; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; PROTEIN DEGRADATION;

APOPTOSIS; CDC2 PROTEIN KINASE; CELL CYCLE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; G2 PHASE; HELA CELLS; HUMANS; KINETICS; MITOSIS; NOCODAZOLE; PACLITAXEL; PERYLENE; PHOTOCHEMOTHERAPY; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; VINBLASTINE;

EID: 0037020254     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M204348200     Document Type: Article

References (76)

1. Pass, H. I., (1993) J. Natl. Cancer Inst. 85, 443-456
2. Dougherty, T. J., Gomer, C. J., Henderson, B., Jori, G., Kessel, D., Korbelik, M., Moan, J., and Peng, Q. (1998) J. Natl. Cancer Inst. 90, 889-905
3. Sharman, W. M., Allen, C. M., and van Lier, J. E. (1999) Drug Discov. Today 4, 507-517
4. Ahmad, N., and Mukhtar, H. (2000) Methods Enzymol. 319, 342-359
5. Oleinick, N. L., and Evans H. H. (1998) Radiat, Res. 150, S146-S156
6. Agostinis, P., Vantieghem, A., Merlevede, W., and de Witte, P. A. M. (2002) Int. J. Biochem. Cell Biol. 34, 221-241
7. Moor, A. C. (2000) J. Photochem. Photobiol. B 57, 1-13
8. Matroule, J. Y., Carthy, C. M., Granville, D. J., Jolois, O., Hunt, D. W., and Piette, J. (2001) Oncogene 20, 4070-4084
9. Vantieghem, A., Assefa, Z., Vandenabeele, P., Declercq, W., Courtois, S., Vandenheede, J. R., Merlevede, W., de Witte, P., and Agostinis, P., (1998) FEBS Lett. 440, 19-24
10. Vantieghem, A., Xu, Y., Declercq, W., Vandenabeele, P., Denecker, G., Vandenheede, J. R., Merlevede, W., de Witte, P. A and Agostinis, P. (2001) Photochem. Photobiol. 74, 133-142
11. Kamuhabwa, A. R., Agostinis, P. M, D'Hallewin, M. A., Baert, L., and de Witte, P. A. (2001) Photochem. Photobiol. 74, 126-132
12. Assefa, Z., Vantieghem, A., Declercq, W., Vandenabeele, P., Vandenheede, J. R., Merlevede, W., de Witte, P., and Agostinis, P. (1999) J. Biol. Chem. 274, 8788-8796
13. Chaloupka, R., Petit, P. X., Israel, N., and Sureau, F. (1999) FEBS Lett. 462, 295-301
14. Adams, J. M., and Cory, S. (1998) Science 281, 1322-1326
15. Huang, D. C., O'Reilly, L. A., Strasser, A., and Cory, S. (1997) EMBO J. 16, 4628-4638
16. Vairo, G., Innes, K. M., and Adams, J. M. (1996) Oncogene 13, 1511-1519
17. Vairo, G., Soos, T. J., Upton, T. M., Zalvide, J., DeCaprio, J. A., Ewen, M. E., Koff, A., and Adams, J. M. (2000) Mol. Cell. Biol. 20, 4745-4753
18. Fadeel, B., Zhivotovsky, B., and Orrenius, S. (1999) FASEB J. 13, 1647-1657
19. Blagosklonny, M. V. (2001) Leukemia 15, 869-874
20. Blagosklonny, M. V., Giannakakou, P., el-Deiry, W. S., Kingston, D. G., Higgs, P. I., Neckers, L., and Fojo, T. (1997) Cancer Res. 57, 130-135
21. May, W. S., Tyler, P. G., Ito, T., Armstrong, D. K., Qatsha, K. A., and Davidson, N. E. (1994) J. Biol. Chem. 269, 26865-26870
22. Ruvolo, P. P., Deng, X., Carr, B. K., and May, W. S. (1998) J. Biol. Chem. 273, 25436-25442
23. Srivastava, R. K., Srivastava, A. R., Korsmeyer, S. J., Nesterova, M., Cho-Chung, Y. S., and Longo, D. L. (1998) Mol. Cell. Biol. 18, 3509-3517
24. Deng, X., Ruvolo, P., Carr, B. K., and May, W. S., Jr. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 1578-1583
25. Rosini, P., De Chiara, G., Lucibello, M., Garaci, E., Cozzolino, F., and Torcia, M. (2000) Biochem. Biophys. Res. Commun. 278, 753-759
26. Torcia, M. G., De Chiara, G., Nencioni, L., Ammendola, S., Labardi, D., Lucibello, M., Rosini, P., Marlier, L. N., Bonini, P., Dello Sbarba, P., Palamara, A., Zambrano, N., Russo, T., Garaci, E., and Cozzolino, F. (2001) J. Biol. Chem. 276, 39027-39036
27. Deng, X., Xiao, L., Lang, W., Gao, F., Ruvolo, P., and May, W. S., Jr. (2001) J. Biol. Chem. 276, 23681-23688
28. Maundrell, K., Antonsson, B., Magnenat, E., Camps, M., Muda, M., Chabert, C., Gillieron, C., Boschert, U., Vial-Knecht, E., Martinou, J.-C., and Arkinstall, S. (1997) J. Biol. Chem. 272, 25238-25242
29. Yamamoto, K., Ichijo, H., and Korsmeyer, S. J. (1999) Mol. Cell. Biol. 19, 8469-8478
30. Fan, M., Goodwin, M., Vu, T., Brantley-Finley, C., Gaarde, W. A., and Chambers, T. C. (2000) J. Biol. Chem. 275, 29980-29985
31. Srivastava, R. K., Mi, Q. S., Hardwick, J. M., and Longo, D. L. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3775-3780
32. Basu, A., You, S. A., and Haldar, S. (2000) Int. J. Oncol. 16, 497-500
33. Ling, Y. H., Tornos, C., and Perez-Soler, R. (1998) J. Biol. Chem. 273, 18984-18991
34. Furukawa, Y., Iwase, S., Kikuchi, J., Terui, Y., Nakamura, M., Yamada, H., Kano, Y., and Matsuda, M. (2000) J. Biol. Chem. 275, 21661-21667
35. Pathan, N., Aime-Sempe, C., Kitada, S., Haldar, S., and Reed, J. C. (2001) Neoplasia 3, 70-79
36. Ito, T., Deng, X., Carr, B., and May, W. S. (1997) J. Biol. Chem. 272, 11671-11673
37. Horiuchi, M., Hayashida, W., Kambe, T., Yamada, T., and Dzau, V. J. (1997) J. Biol. Chem. 272, 19022-19026
38. Deng, X., Kornblau, S. M., Ruvolo, P. P., and May, W. S., Jr. (2000). J. Natl. Cancer Inst. Monogr. 28, 30-37
39. Haldar, S., Jena, N., and Croce, C. M. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4507-4511
40. Haldar, S., Chintapalli, J., and Croce, C. M. (1996) Cancer Res. 56, 1253-1255
41. Fan, M., Du, L., Stone, A. A., Gilbert, K. M., and Chambers, T. C. (2000) Cancer Res. 60, 6403-6407
42. Scatena, C. D., Stewart, Z. A., Mays, D., Tang, L. J., Keefer, C. J., Leach, S. D., and Pietenpol, J. A. (1998) J. Biol. Chem. 273, 30777-30784
43. Granville, D. J., Jiang, H., An, M. T., Levy, J. G., McManus, B. M., and Hunt, D. W. (1999) Br. J. Cancer 79, 95-100
44. He, J., Agarwal, M. L., Larkin, H. E., Friedman, L. R., Xue, L. Y., and Oleinick, N. L. (1996) Photochem. Photobiol. 64, 845-852
45. Kim, H. R., Luo, Y., Li, G., and Kessel, D. (1999) Cancer Res. 59, 3429-3432
46. Srivastava, M., Ahmad, N., Gupta, S., and Mukhtar, H. (2001) J. Biol. Chem. 276, 15481-15488
47. Kessel, D., and Castelli, M. (2001) Photochem. Photobiol. 74, 318-322
48. Vandenbogaerde, A. L., Cuveele, J. F., Proot, P., Himpens, B. E., Merlevede, W. J., and de Witte, P. A. (1997) J. Photochem. Photobiol. B 38, 136-142
49. Assefa, Z., Garmyn, M., Bouillon, R., Merlevede, W., Vandenheede, J. R., and Agostinis, P. (1997) J. Invest. Dermatol. 108, 886-891
50. Poruchynsky, M. S., Wang, E. E., Rudin, C. M., Blagosklonny, M. V., and Fojo, T. (1998) Cancer Res. 58, 3331-3338
51. Boudrez, A., Beullens, M., Groenen, P., Van Eynde, A., Vulsteke, V., Jagiello, I., Murray, M., Krainer, A. R., Stalmans, W., and Bollen, M. (2000) J. Biol. Chem. 275, 25411-25417
52. Blagosklonny, M. V., and Fojo T. (1999) Int. J. Cancer 83, 151-156
53. Zhou, S., Clemens, J. C., Hakes, D. J., Barford, D., and Dixon, J. E. (1993) J. Biol. Chem. 268, 17754-17761
54. Stein, G. S., and Stein, J. L. (1989) in Cell Growth and Division (Baserga, R., ed) pp. 133-137, IRL Press/Oxford University Press, Oxford, United Kingdom
55. Lewis, T. S, Shapiro, P. S., and Ahn, N. G. (1998) Adv. Cancer Res. 74, 49-139
56. Yan, M., Dai, T., Deak, J. C., Kyriakis, J. M., Zon, L. I., Woodgett, J. R., and Templeton, D. J. (1994) Nature 372, 798-800
57. Arion, D., Meijer, L., Brizuela, L., and Beach, D. (1988) Cell 55, 371-378
58. Morgan, D. O. (1995) Nature 374, 131-134
59. Meijer, L., Borgne, A., Mulner, O., Chong, J. P., Blow, J. J., Inagaki, N., Inagaki, M., Delcros, J. G., and Moulinoux, J. P. (1997) Eur. J. Biochem. 243, 527-536
60. Leclerc, S., Garnier, M., Hoessel, R., Marko, D., Bibb, J. A., Snyder, G. L., Greengard, P., Biernat, J., Wu, Y. Z., Mandelkow, E. M., Eisenbrand, G., and Meijer, L. (2001) J. Biol. Chem. 276, 251-260
61. Rialet, V., and Meijer, L. (1991) Anticancer Res. 11, 1581-1590
62. Krajewski, S., Tanaka, S., Takayama, S., Schibler, M. J., Fenton, W., and Reed, J. C. (1993) Cancer Res. 53, 4701-4714
63. Newton, K., and Strasser, A. (1998) Curr. Opin. Genet. Dev. 8, 68-75
64. Pines, J., and Hunter, T. (1991) J. Cell Biol. 115, 1-17
65. Bailly, E., Doree, M., Nurse, P., and Bornens, M. (1989) EMBO J. 8, 3985-3995
66. De Souza, C. P., Ellem, K. A., and Gabrielli, B. G., (2000) Exp. Cell Res. 257, 11-21
67. Basu, A., and Haldar, S. (1998) Int. J. Oncol. 13, 659-664
68. Haldar, S., Basu, A., and Croce, C. M. (1998) Cancer Res. 58, 1609-1615
69. Jordan, A., Hadfield, J. A, Lawrence, N. J., and McGown, A. T. (1998) Med. Res. Rev. 18, 259-296
70. Juarranz, A., Espada, J., Stockert, J. C., Villanueva, A., Polo, S., Dominguez, V., and Canete, M. (2001) Photochem. Photobiol. 73, 283-289
71. Berg, K., and Moan, J. (1997) Photochem. Photobiol. 65, 403-409
72. Stockert, J. C., Juarranz, A., Villanueva, A., and Canete, M. (1996) Cancer Chemother. Pharmacol. 39, 167-169
73. Yvon, A. M., Wadsworth, P., and Jordan, M. A. (1999) Mol. Biol. Cell. 10, 947-959
74. Ngan, V. K., Bellman, K., Hill, B. T., Wilson, L., and Jordan, M. A. (2001) Mol. Pharmacol. 60, 225-232
75. Ruvolo, P. P., Deng, X., and May, W. S. (2001) Leukemia 15, 515-522
76. Zhou, X. Z., Lu, P. J., Wulf, G., and Lu, K. P. (1999) Cell. Mol. Life Sci. 56, 788-806