-
1
-
-
84934436717
-
Molecular targets of curcumin
-
Lin, J.K. Molecular targets of curcumin. Adv. Exp. Med. Biol. 2007, 595, 227-243.
-
(2007)
Adv. Exp. Med. Biol
, vol.595
, pp. 227-243
-
-
Lin, J.K.1
-
2
-
-
45849088463
-
Curcumin: Biological and Medicinal properties
-
CRC Press: New York, NY, USA
-
Aggarwal, B.B.; Bhatt, I.D.; Ichikawa, H.; Ahn, K.S.; Sethi, G.; Sandur, S.K.; Sundaram, C.; Seeram, N.; Shishodia, S. Curcumin: Biological and Medicinal properties. In Turmeric: The genus Curcuma; CRC Press: New York, NY, USA, 2007; Vol. 45, pp. 297-368.
-
(2007)
Turmeric: The Genus Curcuma
, vol.45
, pp. 297-368
-
-
Aggarwal, B.B.1
Bhatt, I.D.2
Ichikawa, H.3
Ahn, K.S.4
Sethi, G.5
Sandur, S.K.6
Sundaram, C.7
Seeram, N.8
Shishodia, S.9
-
3
-
-
38749109673
-
Curcumin as Curecumin: From kitchen to clinic
-
Goel, A.; Kunnumakkara, A.B.; Aggarwal, B.B. Curcumin as Curecumin: From kitchen to clinic. Biochem. Pharmacol. 2008, 75, 787-809.
-
(2008)
Biochem. Pharmacol
, vol.75
, pp. 787-809
-
-
Goel, A.1
Kunnumakkara, A.B.2
Aggarwal, B.B.3
-
4
-
-
44749093175
-
Curcumin: From ancient medicine to current clinical trials
-
Hatcher, H.; Planalp, R.; Cho, J.; Torti, F.M.; Torti, S.V. Curcumin: From ancient medicine to current clinical trials. Cell. Mol. Life Sci. 2008, 65, 1631-1652.
-
(2008)
Cell. Mol. Life Sci
, vol.65
, pp. 1631-1652
-
-
Hatcher, H.1
Planalp, R.2
Cho, J.3
Torti, F.M.4
Torti, S.V.5
-
5
-
-
33746197963
-
Multiple molecular targets in cancer chemoprevention by curcumin
-
Thangapazham, R.L.; Sharma, A.; Maheshwari, R.K. Multiple molecular targets in cancer chemoprevention by curcumin. AAPS J. 2006, 8, E443-449.
-
(2006)
AAPS J
, vol.8
-
-
Thangapazham, R.L.1
Sharma, A.2
Maheshwari, R.K.3
-
6
-
-
33645648062
-
Dose escalation of a curcuminoid formulation
-
Lao, C.D.; Ruffin, M.T. IV.; Normolle, D.; Heath, D.D.; Murray, S.I.; Bailey, J.M.; Boggs, M.E.; Crowell, J.; Rock, C.L.; Brenner, D.E. Dose escalation of a curcuminoid formulation. BMC Complement. Altern. Med. 2006, 6, 10.
-
(2006)
BMC Complement. Altern. Med
, vol.6
, pp. 10
-
-
Lao, C.D.1
Ruffin, M.T.I.V.2
Normolle, D.3
Heath, D.D.4
Murray, S.I.5
Bailey, J.M.6
Boggs, M.E.7
Crowell, J.8
Rock, C.L.9
Brenner, D.E.10
-
7
-
-
0037291286
-
Safety and anti-inflammatory activity of curcumin: A component of tumeric (Curcuma longa)
-
Chainani-Wu, N. Safety and anti-inflammatory activity of curcumin: A component of tumeric (Curcuma longa). J. Altern. Complement. Med. 2003, 9, 161-168.
-
(2003)
J. Altern. Complement. Med
, vol.9
, pp. 161-168
-
-
Chainani-Wu, N.1
-
8
-
-
0035174504
-
Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions
-
Cheng, A.L.; Hsu, C.H.; Lin, J.K.; Hsu, M.M.; Ho, Y.F.; Shen, T.S.; Ko, J.Y.; Lin, J.T.; Lin, B.R.; Ming-Shiang, W.; Yu, H.S.; Jee, S.H.; Chen, G.S.; Chen, T.M.; Chen, C.A.; Lai, M.K.; Pu, Y.S.; Pan, M.H.; Wang, Y.J.; Tsai, C.C.; Hsieh, C.Y. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res. 2001, 21, 2895-2900.
-
(2001)
Anticancer Res
, vol.21
, pp. 2895-2900
-
-
Cheng, A.L.1
Hsu, C.H.2
Lin, J.K.3
Hsu, M.M.4
Ho, Y.F.5
Shen, T.S.6
Ko, J.Y.7
Lin, J.T.8
Lin, B.R.9
Ming-Shiang, W.10
Yu, H.S.11
Jee, S.H.12
Chen, G.S.13
Chen, T.M.14
Chen, C.A.15
Lai, M.K.16
Pu, Y.S.17
Pan, M.H.18
Wang, Y.J.19
Tsai, C.C.20
Hsieh, C.Y.21
more..
-
9
-
-
6044276740
-
Phase I clinical trial of oral curcumin: Biomarkers of systemic activity and compliance
-
Sharma, R.A.; Euden, S.A.; Platton, S.L.; Cooke, D.N.; Shafayat, A.; Hewitt, H.R.; Marczylo, T.H.; Morgan, B.; Hemingway, D.; Plummer, S.M.; Pirmohamed, M.; Gescher, A.J.; Steward, W. P. Phase I clinical trial of oral curcumin: Biomarkers of systemic activity and compliance. Clin. Cancer Res. 2004, 10, 6847-6854.
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 6847-6854
-
-
Sharma, R.A.1
Euden, S.A.2
Platton, S.L.3
Cooke, D.N.4
Shafayat, A.5
Hewitt, H.R.6
Marczylo, T.H.7
Morgan, B.8
Hemingway, D.9
Plummer, S.M.10
Pirmohamed, M.11
Gescher, A.J.12
Steward, W.P.13
-
10
-
-
0034772953
-
Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer
-
Sharma, R.A.; McLelland, H.R.; Hill, K.A.; Ireson, C.R.; Euden, S.A.; Manson, M.M.; Pirmohamed, M.; Marnett, L.J.; Gescher, A.J.; Steward, W.P. Pharmacodynamic and pharmacokinetic study of oral Curcuma extract in patients with colorectal cancer. Clin. Cancer Res. 2001, 7, 1894-1900.
-
(2001)
Clin. Cancer Res
, vol.7
, pp. 1894-1900
-
-
Sharma, R.A.1
McLelland, H.R.2
Hill, K.A.3
Ireson, C.R.4
Euden, S.A.5
Manson, M.M.6
Pirmohamed, M.7
Marnett, L.J.8
Gescher, A.J.9
Steward, W.P.10
-
11
-
-
37549051274
-
Bioavailability of curcumin: Problems and promises
-
Anand, P.; Kunnumakkara, A.B.; Newman, R.A.; Aggarwal, B.B. Bioavailability of curcumin: Problems and promises. Mol. Pharm. 2007, 4, 807-818.
-
(2007)
Mol. Pharm
, vol.4
, pp. 807-818
-
-
Anand, P.1
Kunnumakkara, A.B.2
Newman, R.A.3
Aggarwal, B.B.4
-
12
-
-
77449124082
-
The dark side of curcumin
-
DOI: 10.1002/ijc.24967
-
Burgos-Moron, E.; Calderon-Montano, J.M.; Salvador, J.; Robles, A.; Lopez-Lazaro, M. The dark side of curcumin. Int. J. Cancer 2009, 9999, DOI: 10.1002/ijc.24967.
-
(2009)
Int. J. Cancer
, vol.9999
-
-
Burgos-Moron, E.1
Calderon-Montano, J.M.2
Salvador, J.3
Robles, A.4
Lopez-Lazaro, M.5
-
13
-
-
12844277237
-
Consumption of the putative chemopreventive agent curcumin by cancer patients: Assessment of curcumin levels in the colorectum and their pharmacodynamic consequences
-
Garcea, G.; Berry, D.P.; Jones, D.J.; Singh, R.; Dennison, A.R.; Farmer, P.B.; Sharma, R.A.; Steward, W.P.; Gescher, A.J. Consumption of the putative chemopreventive agent curcumin by cancer patients: Assessment of curcumin levels in the colorectum and their pharmacodynamic consequences. Cancer Epidem. Biomarker. Prev. 2005, 14, 120-125.
-
(2005)
Cancer Epidem. Biomarker. Prev
, vol.14
, pp. 120-125
-
-
Garcea, G.1
Berry, D.P.2
Jones, D.J.3
Singh, R.4
Dennison, A.R.5
Farmer, P.B.6
Sharma, R.A.7
Steward, W.P.8
Gescher, A.J.9
-
14
-
-
0035667365
-
Clinical development of leukocyte cyclooxygenase 2 activity as a systemic biomarker for cancer chemopreventive agents
-
Plummer, S.M.; Hill, K.A.; Festing, M.F.; Steward, W.P.; Gescher, A.J.; Sharma, R.A. Clinical development of leukocyte cyclooxygenase 2 activity as a systemic biomarker for cancer chemopreventive agents. Cancer Epidem. Biomarker. Prev. 2001, 10, 1295-1299.
-
(2001)
Cancer Epidem. Biomarker. Prev
, vol.10
, pp. 1295-1299
-
-
Plummer, S.M.1
Hill, K.A.2
Festing, M.F.3
Steward, W.P.4
Gescher, A.J.5
Sharma, R.A.6
-
15
-
-
0029979805
-
Involvement of the beta-diketone moiety in the antioxidative mechanism of tetrahydrocurcumin
-
Sugiyama, Y.; Kawakishi, S.; Osawa, T. Involvement of the beta-diketone moiety in the antioxidative mechanism of tetrahydrocurcumin. Biochem. Pharmacol. 1996, 52, 519-525.
-
(1996)
Biochem. Pharmacol
, vol.52
, pp. 519-525
-
-
Sugiyama, Y.1
Kawakishi, S.2
Osawa, T.3
-
16
-
-
34548058841
-
Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and antiproliferative responses through a ROS-independent mechanism
-
Sandur, S.K.; Pandey, M.K.; Sung, B.; Ahn, K.S.; Murakami, A.; Sethi, G.; Limtrakul, P.; Badmaev, V.; Aggarwal, B.B. Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and antiproliferative responses through a ROS-independent mechanism. Carcinogenesis 2007, 28, 1765-1773.
-
(2007)
Carcinogenesis
, vol.28
, pp. 1765-1773
-
-
Sandur, S.K.1
Pandey, M.K.2
Sung, B.3
Ahn, K.S.4
Murakami, A.5
Sethi, G.6
Limtrakul, P.7
Badmaev, V.8
Aggarwal, B.B.9
-
17
-
-
33846066817
-
Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives
-
Somparn, P.; Phisalaphong, C.; Nakornchai, S.; Unchern, S.; Morales, N.P. Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives. Biol. Pharm. Bull. 2007, 30, 74-78.
-
(2007)
Biol. Pharm. Bull
, vol.30
, pp. 74-78
-
-
Somparn, P.1
Phisalaphong, C.2
Nakornchai, S.3
Unchern, S.4
Morales, N.P.5
-
18
-
-
64049090200
-
Synthesis, cytotoxic and combined cDDP activity of new stable curcumin derivatives
-
Ferrari, E.; Lazzari, S.; Marverti, G.; Pignedoli, F.; Spagnolo, F.; Saladini, M., Synthesis, cytotoxic and combined cDDP activity of new stable curcumin derivatives. Bioorg. Med. Chem. 2009, 17, 3043-3052.
-
(2009)
Bioorg. Med. Chem
, vol.17
, pp. 3043-3052
-
-
Ferrari, E.1
Lazzari, S.2
Marverti, G.3
Pignedoli, F.4
Spagnolo, F.5
Saladini, M.6
-
19
-
-
55949084512
-
Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature
-
Anand, P.; Thomas, S.G.; Kunnumakkara, A.B.; Sundaram, C.; Harikumar, K.B.; Sung, B.; Tharakan, S.T.; Misra, K.; Priyadarsini, I.K.; Rajasekharan, K.N.; Aggarwal, B.B. Biological activities of curcumin and its analogues (Congeners) made by man and Mother Nature. Biochem. Pharmacol. 2008, 76, 1590-1611.
-
(2008)
Biochem. Pharmacol
, vol.76
, pp. 1590-1611
-
-
Anand, P.1
Thomas, S.G.2
Kunnumakkara, A.B.3
Sundaram, C.4
Harikumar, K.B.5
Sung, B.6
Tharakan, S.T.7
Misra, K.8
Priyadarsini, I.K.9
Rajasekharan, K.N.10
Aggarwal, B.B.11
-
20
-
-
70449637229
-
Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo
-
Anand, P.; Nair, H.B.; Sung, B.; Kunnumakkara, A.B.; Yadav, V.R.; Tekmal, R.R.; Aggarwal, B.B. Design of curcumin-loaded PLGA nanoparticles formulation with enhanced cellular uptake, and increased bioactivity in vitro and superior bioavailability in vivo. Biochem. Pharmacol. 2010, 79, 330-338.
-
(2010)
Biochem. Pharmacol
, vol.79
, pp. 330-338
-
-
Anand, P.1
Nair, H.B.2
Sung, B.3
Kunnumakkara, A.B.4
Yadav, V.R.5
Tekmal, R.R.6
Aggarwal, B.B.7
-
21
-
-
34248205135
-
Polymeric nanoparticleencapsulated curcumin (nanocurcumin): A novel strategy for human cancer therapy
-
Bisht, S.; Feldmann, G.; Soni, S.; Ravi, R.; Karikar, C.; Maitra, A. Polymeric nanoparticleencapsulated curcumin (nanocurcumin): A novel strategy for human cancer therapy. J. Nanobiotechnol. 2007, 5, 3.
-
(2007)
J. Nanobiotechnol
, vol.5
, pp. 3
-
-
Bisht, S.1
Feldmann, G.2
Soni, S.3
Ravi, R.4
Karikar, C.5
Maitra, A.6
-
22
-
-
66149107051
-
Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice
-
Narayanan, N.K.; Nargi, D.; Randolph, C.; Narayanan, B.A. Liposome encapsulation of curcumin and resveratrol in combination reduces prostate cancer incidence in PTEN knockout mice. Int. J. Cancer 2009, 125, 1-8.
-
(2009)
Int. J. Cancer
, vol.125
, pp. 1-8
-
-
Narayanan, N.K.1
Nargi, D.2
Randolph, C.3
Narayanan, B.A.4
-
23
-
-
45849083928
-
Evaluation of a nanotechnology-based carrier for delivery of curcumin in prostate cancer cells
-
Thangapazham, R.L.; Puri, A.; Tele, S.; Blumenthal, R.; Maheshwari, R.K. Evaluation of a nanotechnology-based carrier for delivery of curcumin in prostate cancer cells. Int. J. Oncol. 2008, 32, 1119-1123.
-
(2008)
Int. J. Oncol
, vol.32
, pp. 1119-1123
-
-
Thangapazham, R.L.1
Puri, A.2
Tele, S.3
Blumenthal, R.4
Maheshwari, R.K.5
-
24
-
-
70349238695
-
Novel artemisinin and curcumin micellar formulations: Drug solubility studies by NMR spectroscopy
-
Lapenna, S.; Bilia, A.R.; Morris, G.A.; Nilsson, M. Novel artemisinin and curcumin micellar formulations: Drug solubility studies by NMR spectroscopy. J. Pharm. Sci. 2009, 98, 3666-3675.
-
(2009)
J. Pharm. Sci
, vol.98
, pp. 3666-3675
-
-
Lapenna, S.1
Bilia, A.R.2
Morris, G.A.3
Nilsson, M.4
-
25
-
-
67349107075
-
Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer
-
Shaikh, J.; Ankola, D.D.; Beniwal, V.; Singh, D.; Kumar, M.N. Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. Eur. J. Pharm. Sci. 2009, 37, 223-230.
-
(2009)
Eur. J. Pharm. Sci
, vol.37
, pp. 223-230
-
-
Shaikh, J.1
Ankola, D.D.2
Beniwal, V.3
Singh, D.4
Kumar, M.N.5
-
26
-
-
0031860081
-
Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers
-
Shoba, G.; Joy, D.; Joseph, T.; Majeed, M.; Rajendran, R.; Srinivas, P.S. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998, 64, 353-356.
-
(1998)
Planta Med
, vol.64
, pp. 353-356
-
-
Shoba, G.1
Joy, D.2
Joseph, T.3
Majeed, M.4
Rajendran, R.5
Srinivas, P.S.6
-
27
-
-
10544256600
-
Expression monitoring by hybridization to high-density oligonucleotide arrays
-
Lockhart, D.J.; Dong, H.; Byrne, M.C.; Follettie, M.T.; Gallo, M.V.; Chee, M.S.; Mittmann, M.; Wang, C.; Kobayashi, M.; Horton, H.; Brown, E.L. Expression monitoring by hybridization to high-density oligonucleotide arrays. Nat. Biotechnol. 1996, 14, 1675-1680.
-
(1996)
Nat. Biotechnol
, vol.14
, pp. 1675-1680
-
-
Lockhart, D.J.1
Dong, H.2
Byrne, M.C.3
Follettie, M.T.4
Gallo, M.V.5
Chee, M.S.6
Mittmann, M.7
Wang, C.8
Kobayashi, M.9
Horton, H.10
Brown, E.L.11
-
28
-
-
0028806048
-
Quantitative monitoring of gene expression patterns with a complementary DNA microarray
-
Schena, M.; Shalon, D.; Davis, R.W.; Brown, P.O. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995, 270, 467-470.
-
(1995)
Science
, vol.270
, pp. 467-470
-
-
Schena, M.1
Shalon, D.2
Davis, R.W.3
Brown, P.O.4
-
29
-
-
5444230182
-
From chemoprevention to chemotherapy: Common targets and common goals
-
Aggarwal, B.B.; Takada, Y.; Oommen, O.V. From chemoprevention to chemotherapy: Common targets and common goals. Expert Opin. Investig. Drugs 2004, 13, 1327-1338.
-
(2004)
Expert Opin. Investig. Drugs
, vol.13
, pp. 1327-1338
-
-
Aggarwal, B.B.1
Takada, Y.2
Oommen, O.V.3
-
30
-
-
70350225860
-
Harnessing the fruits of nature for the development of multi-targeted cancer therapeutics
-
Sarkar, F.H.; Li, Y. Harnessing the fruits of nature for the development of multi-targeted cancer therapeutics. Canc. Treat. Rev. 2009, 35, 597-607.
-
(2009)
Canc. Treat. Rev
, vol.35
, pp. 597-607
-
-
Sarkar, F.H.1
Li, Y.2
-
31
-
-
68849108869
-
Inflammation and cancer: How friendly is the relationship for cancer patients
-
Aggarwal, B.B.; Gehlot, P. Inflammation and cancer: How friendly is the relationship for cancer patients? Curr. Opin. Pharmacol. 2009, 9, 351-369.
-
(2009)
Curr. Opin. Pharmacol
, vol.9
, pp. 351-369
-
-
Aggarwal, B.B.1
Gehlot, P.2
-
32
-
-
0037180757
-
Inflammation and cancer
-
Coussens, L.M.; Werb, Z. Inflammation and cancer. Nature 2002, 420, 860-867.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
33
-
-
0028867742
-
Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]
-
Singh, S.; Aggarwal, B.B. Activation of transcription factor NF-kappa B is suppressed by curcumin (diferuloylmethane) [corrected]. J. Biol. Chem. 1995, 270, 24995-25000.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 24995-25000
-
-
Singh, S.1
Aggarwal, B.B.2
-
34
-
-
0033568674
-
Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity
-
Jobin, C.; Bradham, C.A.; Russo, M.P.; Juma, B.; Narula, A.S.; Brenner, D.A.; Sartor, R.B. Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity. J. Immunol. 1999, 163, 3474-3483.
-
(1999)
J. Immunol
, vol.163
, pp. 3474-3483
-
-
Jobin, C.1
Bradham, C.A.2
Russo, M.P.3
Juma, B.4
Narula, A.S.5
Brenner, D.A.6
Sartor, R.B.7
-
35
-
-
0037305821
-
Curcumin (diferuloylmethane) downregulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
-
Bharti, A.C.; Donato, N.; Singh, S.; Aggarwal, B.B. Curcumin (diferuloylmethane) downregulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood 2003, 101, 1053-1062.
-
(2003)
Blood
, vol.101
, pp. 1053-1062
-
-
Bharti, A.C.1
Donato, N.2
Singh, S.3
Aggarwal, B.B.4
-
36
-
-
23444449848
-
Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogenactivated/extracellular signal-regulated protein kinase pathway and the Akt pathway
-
Siwak, D.R.; Shishodia, S.; Aggarwal, B.B.; Kurzrock, R. Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogenactivated/extracellular signal-regulated protein kinase pathway and the Akt pathway. Cancer 2005, 104, 879-890.
-
(2005)
Cancer
, vol.104
, pp. 879-890
-
-
Siwak, D.R.1
Shishodia, S.2
Aggarwal, B.B.3
Kurzrock, R.4
-
37
-
-
0042168966
-
Curcumin (diferuloylmethane) downregulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: Correlation with suppression of COX-2, MMP-9 and cyclin D1
-
Shishodia, S.; Potdar, P.; Gairola, C.G.; Aggarwal, B.B. Curcumin (diferuloylmethane) downregulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: Correlation with suppression of COX-2, MMP-9 and cyclin D1. Carcinogenesis 2003, 24, 1269-1279.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1269-1279
-
-
Shishodia, S.1
Potdar, P.2
Gairola, C.G.3
Aggarwal, B.B.4
-
38
-
-
34247229225
-
Curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3,5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway
-
Deeb, D.; Jiang, H.; Gao, X.; Al-Holou, S.; Danyluk, A.L.; Dulchavsky, S.A.; Gautam, S.C. Curcumin [1,7-bis(4-hydroxy-3-methoxyphenyl)-1-6-heptadine-3,5-dione; C21H20O6] sensitizes human prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L-induced apoptosis by suppressing nuclear factor-kappaB via inhibition of the prosurvival Akt signaling pathway. J. Pharmacol. Exp. Ther. 2007, 321, 616-625.
-
(2007)
J. Pharmacol. Exp. Ther
, vol.321
, pp. 616-625
-
-
Deeb, D.1
Jiang, H.2
Gao, X.3
Al-Holou, S.4
Danyluk, A.L.5
Dulchavsky, S.A.6
Gautam, S.C.7
-
39
-
-
34347221946
-
Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors
-
Dhandapani, K.M.; Mahesh, V.B.; Brann, D.W. Curcumin suppresses growth and chemoresistance of human glioblastoma cells via AP-1 and NFkappaB transcription factors. J. Neurochem. 2007, 102, 522-538.
-
(2007)
J. Neurochem
, vol.102
, pp. 522-538
-
-
Dhandapani, K.M.1
Mahesh, V.B.2
Brann, D.W.3
-
40
-
-
33749633974
-
Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells
-
Sharma, C.; Kaur, J.; Shishodia, S.; Aggarwal, B.B.; Ralhan, R. Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells. Toxicology 2006, 228, 1-15.
-
(2006)
Toxicology
, vol.228
, pp. 1-15
-
-
Sharma, C.1
Kaur, J.2
Shishodia, S.3
Aggarwal, B.B.4
Ralhan, R.5
-
41
-
-
54749132655
-
Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo
-
Milacic, V.; Banerjee, S.; Landis-Piwowar, K.R.; Sarkar, F.H.; Majumdar, A.P.; Dou, Q.P. Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo. Cancer Res. 2008, 68, 7283-7292.
-
(2008)
Cancer Res
, vol.68
, pp. 7283-7292
-
-
Milacic, V.1
Banerjee, S.2
Landis-Piwowar, K.R.3
Sarkar, F.H.4
Majumdar, A.P.5
Dou, Q.P.6
-
42
-
-
47349100951
-
Natural compounds with proteasome inhibitory activity for cancer prevention and treatment
-
Yang, H.; Landis-Piwowar, K.R.; Chen, D.; Milacic, V.; Dou, Q.P. Natural compounds with proteasome inhibitory activity for cancer prevention and treatment. Curr. Protein Pept. Sci. 2008, 9, 227-239.
-
(2008)
Curr. Protein Pept. Sci
, vol.9
, pp. 227-239
-
-
Yang, H.1
Landis-Piwowar, K.R.2
Chen, D.3
Milacic, V.4
Dou, Q.P.5
-
43
-
-
33847610748
-
The proteasome as a potential target for novel anticancer drugs and chemosensitizers
-
Landis-Piwowar, K.R.; Milacic, V.; Chen, D.; Yang, H.; Zhao, Y.; Chan, T.H.; Yan, B.; Dou, Q.P. The proteasome as a potential target for novel anticancer drugs and chemosensitizers. Drug Resist. Update. 2006, 9, 263-273.
-
(2006)
Drug Resist. Update
, vol.9
, pp. 263-273
-
-
Landis-Piwowar, K.R.1
Milacic, V.2
Chen, D.3
Yang, H.4
Zhao, Y.5
Chan, T.H.6
Yan, B.7
Dou, Q.P.8
-
44
-
-
50449099855
-
Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin
-
Kasinski, A.L.; Du, Y.; Thomas, S.L.; Zhao, J.; Sun, S.Y.; Khuri, F.R.; Wang, C.Y.; Shoji, M.; Sun, A.; Snyder, J.P.; Liotta, D.; Fu, H. Inhibition of IkappaB kinase-nuclear factor-kappaB signaling pathway by 3,5-bis(2-flurobenzylidene)piperidin-4-one (EF24), a novel monoketone analog of curcumin. Mol. Pharmacol. 2008, 74, 654-661.
-
(2008)
Mol. Pharmacol
, vol.74
, pp. 654-661
-
-
Kasinski, A.L.1
Du, Y.2
Thomas, S.L.3
Zhao, J.4
Sun, S.Y.5
Khuri, F.R.6
Wang, C.Y.7
Shoji, M.8
Sun, A.9
Snyder, J.P.10
Liotta, D.11
Fu, H.12
-
45
-
-
1842579486
-
Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis
-
Bharti, A.C.; Shishodia, S.; Reuben, J.M.; Weber, D.; Alexanian, R.; Raj-Vadhan, S.; Estrov, Z.; Talpaz, M.; Aggarwal, B.B. Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis. Blood 2004, 103, 3175-3184.
-
(2004)
Blood
, vol.103
, pp. 3175-3184
-
-
Bharti, A.C.1
Shishodia, S.2
Reuben, J.M.3
Weber, D.4
Alexanian, R.5
Raj-Vadhan, S.6
Estrov, Z.7
Talpaz, M.8
Aggarwal, B.B.9
-
46
-
-
51649118928
-
Phase II trial of curcumin in patients with advanced pancreatic cancer
-
Dhillon, N.; Aggarwal, B.B.; Newman, R.A.; Wolff, R.A.; Kunnumakkara, A.B.; Abbruzzese, J.L.; Ng, C.S.; Badmaev, V.; Kurzrock, R. Phase II trial of curcumin in patients with advanced pancreatic cancer. Clin. Cancer Res. 2008, 14, 4491-4499.
-
(2008)
Clin. Cancer Res
, vol.14
, pp. 4491-4499
-
-
Dhillon, N.1
Aggarwal, B.B.2
Newman, R.A.3
Wolff, R.A.4
Kunnumakkara, A.B.5
Abbruzzese, J.L.6
Ng, C.S.7
Badmaev, V.8
Kurzrock, R.9
-
47
-
-
25844459154
-
NF-kappa B: Linking inflammation and immunity to cancer development and progression
-
Karin, M.; Greten, F.R., NF-kappa B: Linking inflammation and immunity to cancer development and progression. Nat. Rev. Immunol. 2005, 5, 749-759.
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
48
-
-
34250654084
-
Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway
-
Lin, Y.G.; Kunnumakkara, A.B.; Nair, A.; Merritt, W.M.; Han, L.Y.; Armaiz-Pena, G.N.; Kamat, A.A.; Spannuth, W.A.; Gershenson, D.M.; Lutgendorf, S.K.; Aggarwal, B.B.; Sood, A.K. Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway. Clin. Cancer Res. 2007, 13, 3423-3430.
-
(2007)
Clin. Cancer Res
, vol.13
, pp. 3423-3430
-
-
Lin, Y.G.1
Kunnumakkara, A.B.2
Nair, A.3
Merritt, W.M.4
Han, L.Y.5
Armaiz-Pena, G.N.6
Kamat, A.A.7
Spannuth, W.A.8
Gershenson, D.M.9
Lutgendorf, S.K.10
Aggarwal, B.B.11
Sood, A.K.12
-
49
-
-
19344367506
-
Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression
-
Notarbartolo, M.; Poma, P.; Perri, D.; Dusonchet, L.; Cervello, M.; D'Alessandro, N. Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression. Cancer Lett. 2005, 224, 53-65.
-
(2005)
Cancer Lett
, vol.224
, pp. 53-65
-
-
Notarbartolo, M.1
Poma, P.2
Perri, D.3
Dusonchet, L.4
Cervello, M.5
D'alessandro, N.6
-
50
-
-
0034885358
-
New insights into the role of nuclear factor-kappaB in cell growth regulation
-
Chen, F.; Castranova, V.; Shi, X. New insights into the role of nuclear factor-kappaB in cell growth regulation. Am. J. Pathol. 2001, 159, 387-397.
-
(2001)
Am. J. Pathol
, vol.159
, pp. 387-397
-
-
Chen, F.1
Castranova, V.2
Shi, X.3
-
51
-
-
34648847350
-
Curcumin downregulates the constitutive activity of NF-kappaB and induces apoptosis in novel mouse melanoma cells
-
Marin, Y.E.; Wall, B.A.; Wang, S.; Namkoong, J.; Martino, J.J.; Suh, J.; Lee, H.J.; Rabson, A.B.; Yang, C.S.; Chen, S.; Ryu, J.H. Curcumin downregulates the constitutive activity of NF-kappaB and induces apoptosis in novel mouse melanoma cells. Melanoma Res. 2007, 17, 274-283.
-
(2007)
Melanoma Res
, vol.17
, pp. 274-283
-
-
Marin, Y.E.1
Wall, B.A.2
Wang, S.3
Namkoong, J.4
Martino, J.J.5
Suh, J.6
Lee, H.J.7
Rabson, A.B.8
Yang, C.S.9
Chen, S.10
Ryu, J.H.11
-
52
-
-
43949131788
-
Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-kappaB and STAT3 pathways in Hodgkin's lymphoma cells
-
Mackenzie, G.G.; Queisser, N.; Wolfson, M.L.; Fraga, C.G.; Adamo, A.M.; Oteiza, P.I. Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-kappaB and STAT3 pathways in Hodgkin's lymphoma cells. Int. J. Cancer 2008, 123, 56-65.
-
(2008)
Int. J. Cancer
, vol.123
, pp. 56-65
-
-
Mackenzie, G.G.1
Queisser, N.2
Wolfson, M.L.3
Fraga, C.G.4
Adamo, A.M.5
Oteiza, P.I.6
-
53
-
-
69549084702
-
Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity
-
Sandur, S.K.; Deorukhkar, A.; Pandey, M.K.; Pabon, A.M.; Shentu, S.; Guha, S.; Aggarwal, B.B.; Krishnan, S. Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity. Int. J. Radiat. Oncol. Biol. Phys. 2009, 75, 534-542.
-
(2009)
Int. J. Radiat. Oncol. Biol. Phys
, vol.75
, pp. 534-542
-
-
Sandur, S.K.1
Deorukhkar, A.2
Pandey, M.K.3
Pabon, A.M.4
Shentu, S.5
Guha, S.6
Aggarwal, B.B.7
Krishnan, S.8
-
54
-
-
0035891055
-
Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines
-
Mukhopadhyay, A.; Bueso-Ramos, C.; Chatterjee, D.; Pantazis, P.; Aggarwal, B.B. Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines. Oncogene 2001, 20, 7597-7609.
-
(2001)
Oncogene
, vol.20
, pp. 7597-7609
-
-
Mukhopadhyay, A.1
Bueso-Ramos, C.2
Chatterjee, D.3
Pantazis, P.4
Aggarwal, B.B.5
-
55
-
-
30044446136
-
Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation
-
Aggarwal, S.; Ichikawa, H.; Takada, Y.; Sandur, S.K.; Shishodia, S.; Aggarwal, B.B. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation. Mol. Pharmacol. 2006, 69, 195-206.
-
(2006)
Mol. Pharmacol
, vol.69
, pp. 195-206
-
-
Aggarwal, S.1
Ichikawa, H.2
Takada, Y.3
Sandur, S.K.4
Shishodia, S.5
Aggarwal, B.B.6
-
56
-
-
59449085264
-
Targeting inflammatory pathways for prevention and therapy of cancer: Short-term friend, long-term foe
-
Aggarwal, B.B.; Vijayalekshmi, R.V.; Sung, B. Targeting inflammatory pathways for prevention and therapy of cancer: Short-term friend, long-term foe. Clin. Cancer Res. 2009, 15, 425-430.
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 425-430
-
-
Aggarwal, B.B.1
Vijayalekshmi, R.V.2
Sung, B.3
-
57
-
-
34447299398
-
Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane)
-
Sandur, S.K.; Ichikawa, H.; Pandey, M.K.; Kunnumakkara, A.B.; Sung, B.; Sethi, G.; Aggarwal, B.B. Role of pro-oxidants and antioxidants in the anti-inflammatory and apoptotic effects of curcumin (diferuloylmethane). Free Radic. Biol. Med. 2007, 43, 568-580.
-
(2007)
Free Radic. Biol. Med
, vol.43
, pp. 568-580
-
-
Sandur, S.K.1
Ichikawa, H.2
Pandey, M.K.3
Kunnumakkara, A.B.4
Sung, B.5
Sethi, G.6
Aggarwal, B.B.7
-
58
-
-
65349126101
-
Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway
-
Wang, S.L.; Li, Y.; Wen, Y.; Chen, Y.F.; Na, L.X.; Li, S.T.; Sun, C.H. Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway. Biomed. Environ. Sci. 2009, 22, 32-39.
-
(2009)
Biomed. Environ. Sci
, vol.22
, pp. 32-39
-
-
Wang, S.L.1
Li, Y.2
Wen, Y.3
Chen, Y.F.4
Na, L.X.5
Li, S.T.6
Sun, C.H.7
-
59
-
-
33745685704
-
Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: Suppression of p38, JNK and NF-kappaB p65 as potential targets
-
Moon, D.O.; Jin, C.Y.; Lee, J.D.; Choi, Y.H.; Ahn, S.C.; Lee, C.M.; Jeong, S.C.; Park, Y.M.; Kim, G.Y. Curcumin decreases binding of Shiga-like toxin-1B on human intestinal epithelial cell line HT29 stimulated with TNF-alpha and IL-1beta: Suppression of p38, JNK and NF-kappaB p65 as potential targets. Biol. Pharm. Bull. 2006, 29, 1470-1475.
-
(2006)
Biol. Pharm. Bull
, vol.29
, pp. 1470-1475
-
-
Moon, D.O.1
Jin, C.Y.2
Lee, J.D.3
Choi, Y.H.4
Ahn, S.C.5
Lee, C.M.6
Jeong, S.C.7
Park, Y.M.8
Kim, G.Y.9
-
60
-
-
84934436057
-
Antioxidant and anti-inflammatory properties of curcumin
-
Menon, V.P.; Sudheer, A.R. Antioxidant and anti-inflammatory properties of curcumin. Adv. Exp. Med. Biol. 2007, 595, 105-125.
-
(2007)
Adv. Exp. Med. Biol
, vol.595
, pp. 105-125
-
-
Menon, V.P.1
Sudheer, A.R.2
-
61
-
-
70350500225
-
STATs in cancer inflammation and immunity: A leading role for STAT3
-
Yu, H.; Pardoll, D.; Jove, R. STATs in cancer inflammation and immunity: A leading role for STAT3. Nat. Rev. Cancer 2009, 9, 798-809.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 798-809
-
-
Yu, H.1
Pardoll, D.2
Jove, R.3
-
62
-
-
69149098253
-
Signal transducer and activator of transcription-3, inflammation, and cancer: How intimate is the relationship
-
Aggarwal, B.B.; Kunnumakkara, A.B.; Harikumar, K.B.; Gupta, S.R.; Tharakan, S.T.; Koca, C.; Dey, S.; Sung, B. Signal transducer and activator of transcription-3, inflammation, and cancer: How intimate is the relationship? Ann. NY Acad. Sci. 2009, 1171, 59-76.
-
(2009)
Ann. NY Acad. Sci
, vol.1171
, pp. 59-76
-
-
Aggarwal, B.B.1
Kunnumakkara, A.B.2
Harikumar, K.B.3
Gupta, S.R.4
Tharakan, S.T.5
Koca, C.6
Dey, S.7
Sung, B.8
-
63
-
-
33750520736
-
Curcumin regulates signal transducer and activator of transcription (STAT) expression in K562 cells
-
Blasius, R.; Reuter, S.; Henry, E.; Dicato, M.; Diederich, M. Curcumin regulates signal transducer and activator of transcription (STAT) expression in K562 cells. Biochem. Pharmacol. 2006, 72, 1547-1554.
-
(2006)
Biochem. Pharmacol
, vol.72
, pp. 1547-1554
-
-
Blasius, R.1
Reuter, S.2
Henry, E.3
Dicato, M.4
Diederich, M.5
-
64
-
-
69149105623
-
Gene expression profiling related to anti-inflammatory properties of curcumin in K562 leukemia cells
-
Teiten, M.H.; Eifes, S.; Reuter, S.; Duvoix, A.; Dicato, M.; Diederich, M. Gene expression profiling related to anti-inflammatory properties of curcumin in K562 leukemia cells. Ann. NY Acad. Sci. 2009, 1171, 391-398.
-
(2009)
Ann. NY Acad. Sci
, vol.1171
, pp. 391-398
-
-
Teiten, M.H.1
Eifes, S.2
Reuter, S.3
Duvoix, A.4
Dicato, M.5
Diederich, M.6
-
65
-
-
29644438937
-
Curcumin induces growtharrest and apoptosis in association with the inhibition of constitutively active JAK-STAT pathway in T cell leukemia
-
Rajasingh, J.; Raikwar, H.P.; Muthian, G.; Johnson, C.; Bright, J.J. Curcumin induces growtharrest and apoptosis in association with the inhibition of constitutively active JAK-STAT pathway in T cell leukemia. Biochem. Biophys. Res. Commun. 2006, 340, 359-368.
-
(2006)
Biochem. Biophys. Res. Commun
, vol.340
, pp. 359-368
-
-
Rajasingh, J.1
Raikwar, H.P.2
Muthian, G.3
Johnson, C.4
Bright, J.J.5
-
66
-
-
33747470228
-
Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane)
-
Chakravarti, N.; Myers, J.N.; Aggarwal, B.B. Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane). Int. J. Cancer 2006, 119, 1268-1275.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 1268-1275
-
-
Chakravarti, N.1
Myers, J.N.2
Aggarwal, B.B.3
-
67
-
-
0141955061
-
Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells
-
Bharti, A.C.; Donato, N.; Aggarwal, B.B. Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells. J. Immunol. 2003, 171, 3863-3871.
-
(2003)
J. Immunol
, vol.171
, pp. 3863-3871
-
-
Bharti, A.C.1
Donato, N.2
Aggarwal, B.B.3
-
68
-
-
70449367087
-
Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas
-
Hutzen, B.; Friedman, L.; Sobo, M.; Lin, L.; Cen, L.; de Angelis, S.; Yamakoshi, H.; Shibata, H.; Iwabuchi, Y.; Lin, J. Curcumin analogue GO-Y030 inhibits STAT3 activity and cell growth in breast and pancreatic carcinomas. Int. J. Oncol. 2009, 35, 867-872.
-
(2009)
Int. J. Oncol
, vol.35
, pp. 867-872
-
-
Hutzen, B.1
Friedman, L.2
Sobo, M.3
Lin, L.4
Cen, L.5
de Angelis, S.6
Yamakoshi, H.7
Shibata, H.8
Iwabuchi, Y.9
Lin, J.10
-
69
-
-
70149085608
-
New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells
-
Lin, L.; Hutzen, B.; Ball, S.; Foust, E.; Sobo, M.; Deangelis, S.; Pandit, B.; Friedman, L.; Li, C.; Li, P.K.; Fuchs, J.; Lin, J. New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells. Cancer Sci. 2009, 100, 1719-1727.
-
(2009)
Cancer Sci
, vol.100
, pp. 1719-1727
-
-
Lin, L.1
Hutzen, B.2
Ball, S.3
Foust, E.4
Sobo, M.5
Deangelis, S.6
Pandit, B.7
Friedman, L.8
Li, C.9
Li, P.K.10
Fuchs, J.11
Lin, J.12
-
70
-
-
61849093694
-
Curcuminoid-phospholipid complex induces apoptosis in mammary epithelial cells by STAT-3 signaling
-
Cucuzza, L.S.; Motta, M.; Miretti, S.; Accornero, P.; Baratta, M. Curcuminoid-phospholipid complex induces apoptosis in mammary epithelial cells by STAT-3 signaling. Exp. Mol. Med. 2008, 40, 647-657.
-
(2008)
Exp. Mol. Med
, vol.40
, pp. 647-657
-
-
Cucuzza, L.S.1
Motta, M.2
Miretti, S.3
Accornero, P.4
Baratta, M.5
-
71
-
-
70349479218
-
Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines
-
Bill, M.A.; Bakan, C.; Benson, D.M., Jr.; Fuchs, J.; Young, G.; Lesinski, G.B. Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines. Mol. Cancer Ther. 2009, 8, 2726-2735.
-
(2009)
Mol. Cancer Ther
, vol.8
, pp. 2726-2735
-
-
Bill, M.A.1
Bakan, C.2
Benson Jr., D.M.3
Fuchs, J.4
Young, G.5
Lesinski, G.B.6
-
72
-
-
38349038806
-
Interferon-alpha resistance can be reversed by inhibition of IFN-alpha-induced COX-2 expression potentially via STAT1 activation in A549 cells
-
Lee, J.; Jung, H.H.; Im, Y.H.; Kim, J.H.; Park, J.O.; Kim, K.; Kim, W.S.; Ahn, J.S.; Jung, C.W.; Park, Y.S.; Kang, W.K.; Park, K. Interferon-alpha resistance can be reversed by inhibition of IFN-alpha-induced COX-2 expression potentially via STAT1 activation in A549 cells. Oncol. Rep. 2006, 15, 1541-1549.
-
(2006)
Oncol. Rep
, vol.15
, pp. 1541-1549
-
-
Lee, J.1
Jung, H.H.2
Im, Y.H.3
Kim, J.H.4
Park, J.O.5
Kim, K.6
Kim, W.S.7
Ahn, J.S.8
Jung, C.W.9
Park, Y.S.10
Kang, W.K.11
Park, K.12
-
73
-
-
28844479049
-
Curcumin inhibits phorbol ester-induced upregulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast pithelial cells
-
Lee, K.W.; Kim, J.H.; Lee, H.J.; Surh, Y.J. Curcumin inhibits phorbol ester-induced upregulation of cyclooxygenase-2 and matrix metalloproteinase-9 by blocking ERK1/2 phosphorylation and NF-kappaB transcriptional activity in MCF10A human breast pithelial cells. Antioxid. Redox Signal. 2005, 7, 1612-1620.
-
(2005)
Antioxid. Redox Signal
, vol.7
, pp. 1612-1620
-
-
Lee, K.W.1
Kim, J.H.2
Lee, H.J.3
Surh, Y.J.4
-
74
-
-
0033613436
-
Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex
-
Plummer, S.M.; Holloway, K.A.; Manson, M.M.; Munks, R.J.; Kaptein, A.; Farrow, S.; Howells, L. Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex. Oncogene 1999, 18, 6013-6020.
-
(1999)
Oncogene
, vol.18
, pp. 6013-6020
-
-
Plummer, S.M.1
Holloway, K.A.2
Manson, M.M.3
Munks, R.J.4
Kaptein, A.5
Farrow, S.6
Howells, L.7
-
75
-
-
27944462172
-
Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression, by curcumin and its analog, alpha-diisoeugenol
-
Atsumi, T.; Murakami, Y.; Shibuya, K.; Tonosaki, K.; Fujisawa, S. Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression, by curcumin and its analog, alpha-diisoeugenol. Anticancer Res. 2005, 25, 4029-4036.
-
(2005)
Anticancer Res
, vol.25
, pp. 4029-4036
-
-
Atsumi, T.1
Murakami, Y.2
Shibuya, K.3
Tonosaki, K.4
Fujisawa, S.5
-
76
-
-
84934436223
-
Regulation of COX and LOX by curcumin
-
Rao, C.V. Regulation of COX and LOX by curcumin. Adv. Exp. Med. Biol. 2007, 595, 213-226.
-
(2007)
Adv. Exp. Med. Biol
, vol.595
, pp. 213-226
-
-
Rao, C.V.1
-
77
-
-
70249136561
-
Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model
-
Kunnumakkara, A.B.; Diagaradjane, P.; Anand, P.; Kuzhuvelil, H.B.; Deorukhkar, A.; Gelovani, J.; Guha, S.; Krishnan, S.; Aggarwal, B.B. Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model. Int. J. Cancer 2009, 125, 2187-2197.
-
(2009)
Int. J. Cancer
, vol.125
, pp. 2187-2197
-
-
Kunnumakkara, A.B.1
Diagaradjane, P.2
Anand, P.3
Kuzhuvelil, H.B.4
Deorukhkar, A.5
Gelovani, J.6
Guha, S.7
Krishnan, S.8
Aggarwal, B.B.9
-
78
-
-
55949119550
-
Prevention and treatment of pancreatic cancer by curcumin in combination with omega-3 fatty acids
-
Swamy, M.V.; Citineni, B.; Patlolla, J.M.; Mohammed, A.; Zhang, Y.; Rao, C.V. Prevention and treatment of pancreatic cancer by curcumin in combination with omega-3 fatty acids. Nutr. Cancer 2008, 60, 81-89.
-
(2008)
Nutr. Cancer
, vol.60
, pp. 81-89
-
-
Swamy, M.V.1
Citineni, B.2
Patlolla, J.M.3
Mohammed, A.4
Zhang, Y.5
Rao, C.V.6
-
79
-
-
4544236324
-
Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: Effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase
-
Hong, J.; Bose, M.; Ju, J.; Ryu, J.H.; Chen, X.; Sang, S.; Lee, M. J.; Yang, C.S. Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: Effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase. Carcinogenesis 2004, 25, 1671-1679.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1671-1679
-
-
Hong, J.1
Bose, M.2
Ju, J.3
Ryu, J.H.4
Chen, X.5
Sang, S.6
Lee, M.J.7
Yang, C.S.8
-
80
-
-
0035976049
-
Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells
-
Goel, A.; Boland, C.R.; Chauhan, D.P. Specific inhibition of cyclooxygenase-2 (COX-2) expression by dietary curcumin in HT-29 human colon cancer cells. Cancer Lett. 2001, 17 2,111-118.
-
(2001)
Cancer Lett
, vol.17
, Issue.2
, pp. 111-118
-
-
Goel, A.1
Boland, C.R.2
Chauhan, D.P.3
-
81
-
-
33845950491
-
Inhibition of pancreatic and lung adenocarcinoma cell survival by curcumin is associated with increased apoptosis, down-regulation of COX-2 and EGFR and inhibitio n of Erk1/2 activity
-
Lev-Ari, S.; Starr, A.; Vexler, A.; Karaush, V.; Loew, V.; Greif, J.; Fenig, E.; Aderka, D.; Ben-Yosef, R. Inhibition of pancreatic and lung adenocarcinoma cell survival by curcumin is associated with increased apoptosis, down-regulation of COX-2 and EGFR and inhibitio n of Erk1/2 activity. Anticancer Res. 2006, 26, 4423-4430.
-
(2006)
Anticancer Res
, vol.26
, pp. 4423-4430
-
-
Lev-Ari, S.1
Starr, A.2
Vexler, A.3
Karaush, V.4
Loew, V.5
Greif, J.6
Fenig, E.7
Aderka, D.8
Ben-Yosef, R.9
-
82
-
-
70350217623
-
Fluorocurcumins as cyclooxygenase-2 inhibitor: Molecular docking, pharmacokinetics and tissue distribution in mice
-
Padhye, S.; Banerjee, S.; Chavan, D.; Pandye, S.; Swamy, K.V.; Ali, S.; Li, J.; Dou, Q.P.; Sarkar, F.H. Fluorocurcumins as cyclooxygenase-2 inhibitor: Molecular docking, pharmacokinetics and tissue distribution in mice. Pharm. Res. 2009, 26, 2438-2445.
-
(2009)
Pharm. Res
, vol.26
, pp. 2438-2445
-
-
Padhye, S.1
Banerjee, S.2
Chavan, D.3
Pandye, S.4
Swamy, K.V.5
Ali, S.6
Li, J.7
Dou, Q.P.8
Sarkar, F.H.9
-
83
-
-
0037069939
-
Curcumininduced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation
-
Mukhopadhyay, A.; Banerjee, S.; Stafford, L.J.; Xia, C.; Liu, M.; Aggarwal, B.B. Curcumininduced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation. Oncogene 2002, 21, 8852-8861.
-
(2002)
Oncogene
, vol.21
, pp. 8852-8861
-
-
Mukhopadhyay, A.1
Banerjee, S.2
Stafford, L.J.3
Xia, C.4
Liu, M.5
Aggarwal, B.B.6
-
84
-
-
37549050536
-
Linkage of curcumin-induced cell cycle arrest and apoptosis by cyclin-dependent kinase inhibitor p21(/WAF1/CIP1)
-
Srivastava, R.K.; Chen, Q.; Siddiqui, I.; Sarva, K.; Shankar, S., Linkage of curcumin-induced cell cycle arrest and apoptosis by cyclin-dependent kinase inhibitor p21(/WAF1/CIP1). Cell Cycle 2007, 6, 2953-2961.
-
(2007)
Cell Cycle
, vol.6
, pp. 2953-2961
-
-
Srivastava, R.K.1
Chen, Q.2
Siddiqui, I.3
Sarva, K.4
Shankar, S.5
-
85
-
-
33847133360
-
Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and upregulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines
-
Aggarwal, B.B.; Banerjee, S.; Bharadwaj, U.; Sung, B.; Shishodia, S.; Sethi, G. Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and upregulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines. Biochem. Pharmacol. 2007, 73, 1024-1032.
-
(2007)
Biochem. Pharmacol
, vol.73
, pp. 1024-1032
-
-
Aggarwal, B.B.1
Banerjee, S.2
Bharadwaj, U.3
Sung, B.4
Shishodia, S.5
Sethi, G.6
-
86
-
-
33646532114
-
The Wnt-dependent signaling pathways as target in oncology drug discovery
-
Janssens, N.; Janicot, M.; Perera, T. The Wnt-dependent signaling pathways as target in oncology drug discovery. Invest. New Drug. 2006, 24, 263-280.
-
(2006)
Invest. New Drug
, vol.24
, pp. 263-280
-
-
Janssens, N.1
Janicot, M.2
Perera, T.3
-
87
-
-
13844293171
-
Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells by targeting beta-catenin-mediated transactivation and cell-cell adhesion pathways
-
Narayan, S. Curcumin, a multi-functional chemopreventive agent, blocks growth of colon cancer cells by targeting beta-catenin-mediated transactivation and cell-cell adhesion pathways. J. Mol. Histol. 2004, 35, 301-307.
-
(2004)
J. Mol. Histol
, vol.35
, pp. 301-307
-
-
Narayan, S.1
-
88
-
-
77954375987
-
Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/beta-catenin antagonists against human osteosarcoma cells
-
DOI: 10.1007/s10637-009-9311-z
-
Leow, P.; Tian, Q.; Ong, Z.; Yang, Z.; Ee, P. Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/beta-catenin antagonists against human osteosarcoma cells. Invest. New Drug. 2009, DOI: 10.1007/s10637-009-9311-z.
-
(2009)
Invest. New Drug
-
-
Leow, P.1
Tian, Q.2
Ong, Z.3
Yang, Z.4
Ee, P.5
-
89
-
-
19444362674
-
The inhibitory mechanism of curcumin and its derivative against beta-catenin/Tcf signaling
-
Park, C.H.; Hahm, E.R.; Park, S.; Kim, H.K.; Yang, C.H. The inhibitory mechanism of curcumin and its derivative against beta-catenin/Tcf signaling. FEBS Lett. 2005, 579, 2965-2971.
-
(2005)
FEBS Lett
, vol.579
, pp. 2965-2971
-
-
Park, C.H.1
Hahm, E.R.2
Park, S.3
Kim, H.K.4
Yang, C.H.5
-
90
-
-
0037028207
-
Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells
-
Jaiswal, A.S.; Marlow, B.P.; Gupta, N.; Narayan, S. Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells. Oncogene 2002, 21, 8414-8427.
-
(2002)
Oncogene
, vol.21
, pp. 8414-8427
-
-
Jaiswal, A.S.1
Marlow, B.P.2
Gupta, N.3
Narayan, S.4
-
91
-
-
77955559259
-
Targeting breast stem cells with the cancer preventive compounds curcumin and piperine
-
DOI: 10.1007/s10549-009-0612-x
-
Kakarala, M.; Brenner, D.E.; Korkaya, H.; Cheng, C.; Tazi, K.; Ginestier, C.; Liu, S.; Dontu, G.; Wicha, M.S. Targeting breast stem cells with the cancer preventive compounds curcumin and piperine. Breast Cancer Res. Treat. 2009, DOI: 10.1007/s10549-009-0612-x.
-
(2009)
Breast Cancer Res. Treat
-
-
Kakarala, M.1
Brenner, D.E.2
Korkaya, H.3
Cheng, C.4
Tazi, K.5
Ginestier, C.6
Liu, S.7
Dontu, G.8
Wicha, M.S.9
-
92
-
-
68849083504
-
Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/beta-catenin signaling
-
Prasad, C.P.; Rath, G.; Mathur, S.; Bhatnagar, D.; Ralhan, R. Potent growth suppressive activity of curcumin in human breast cancer cells: Modulation of Wnt/beta-catenin signaling. Chem. Biol. Interact. 2009, 181, 263-271.
-
(2009)
Chem. Biol. Interact
, vol.181
, pp. 263-271
-
-
Prasad, C.P.1
Rath, G.2
Mathur, S.3
Bhatnagar, D.4
Ralhan, R.5
-
93
-
-
0034019660
-
Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis
-
Mahmoud, N.N.; Carothers, A.M.; Grunberger, D.; Bilinski, R.T.; Churchill, M.R.; Martucci, C.; Newmark, H.L.; Bertagnolli, M.M. Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis. Carcinogenesis 2000, 21, 921-927.
-
(2000)
Carcinogenesis
, vol.21
, pp. 921-927
-
-
Mahmoud, N.N.1
Carothers, A.M.2
Grunberger, D.3
Bilinski, R.T.4
Churchill, M.R.5
Martucci, C.6
Newmark, H.L.7
Bertagnolli, M.M.8
-
94
-
-
14844319300
-
Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin
-
Yan, C.; Jamaluddin, M.S.; Aggarwal, B.; Myers, J.; Boyd, D.D. Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin. Mol. Cancer Ther. 2005, 4, 233-241.
-
(2005)
Mol. Cancer Ther
, vol.4
, pp. 233-241
-
-
Yan, C.1
Jamaluddin, M.S.2
Aggarwal, B.3
Myers, J.4
Boyd, D.D.5
-
95
-
-
56349116715
-
Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300
-
Ryu, M.J.; Cho, M.; Song, J.Y.; Yun, Y.S.; Choi, I.W.; Kim, D.E.; Park, B.S.; Oh, S. Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300. Biochem. Biophys. Res. Commun. 2008, 377, 1304-1308.
-
(2008)
Biochem. Biophys. Res. Commun
, vol.377
, pp. 1304-1308
-
-
Ryu, M.J.1
Cho, M.2
Song, J.Y.3
Yun, Y.S.4
Choi, I.W.5
Kim, D.E.6
Park, B.S.7
Oh, S.8
-
96
-
-
27744534653
-
Inhibition of PI3K/Akt signaling: An emerging paradigm for targeted cancer therapy
-
Chen, Y.L.; Law, P.Y.; Loh, H.H. Inhibition of PI3K/Akt signaling: An emerging paradigm for targeted cancer therapy. Curr. Med. Chem. Anticancer Agents 2005, 5, 575-589.
-
(2005)
Curr. Med. Chem. Anticancer Agents
, vol.5
, pp. 575-589
-
-
Chen, Y.L.1
Law, P.Y.2
Loh, H.H.3
-
97
-
-
0037352170
-
McCubrey, J.A. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy
-
Chang, F.; Lee, J.T.; Navolanic, P.M.; Steelman, L.S.; Shelton, J.G.; Blalock, W.L.; Franklin, R.A.; McCubrey, J.A. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy. Leukemia 2003, 17, 590-603.
-
(2003)
Leukemia
, vol.17
, pp. 590-603
-
-
Chang, F.1
Lee, J.T.2
Navolanic, P.M.3
Steelman, L.S.4
Shelton, J.G.5
Blalock, W.L.6
Franklin, R.A.7
-
98
-
-
33344461738
-
Curcumin induces apoptosis via inhibition of PI3'-kinase/AKT pathway in acute T cell leukemias
-
Hussain, A.R.; Al-Rasheed, M.; Manogaran, P.S.; Al-Hussein, K.A.; Platanias, L.C.; Al Kuraya, K.; Uddin, S. Curcumin induces apoptosis via inhibition of PI3'-kinase/AKT pathway in acute T cell leukemias. Apoptosis 2006, 11, 245-254.
-
(2006)
Apoptosis
, vol.11
, pp. 245-254
-
-
Hussain, A.R.1
Al-Rasheed, M.2
Manogaran, P.S.3
Al-Hussein, K.A.4
Platanias, L.C.5
Al Kuraya, K.6
Uddin, S.7
-
99
-
-
33745918631
-
Curcumin inhibits the mammalian target of rapamycinmediated signaling pathways in cancer cells
-
Beevers, C.S.; Li, F.; Liu, L.; Huang, S. Curcumin inhibits the mammalian target of rapamycinmediated signaling pathways in cancer cells. Int. J. Cancer 2006, 119, 757-764.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 757-764
-
-
Beevers, C.S.1
Li, F.2
Liu, L.3
Huang, S.4
-
100
-
-
68549083507
-
Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling
-
Johnson, S.M.; Gulhati, P.; Arrieta, I.; Wang, X.; Uchida, T.; Gao, T.; Evers, B.M. Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling. Anticancer Res. 2009, 29, 3185-3190.
-
(2009)
Anticancer Res
, vol.29
, pp. 3185-3190
-
-
Johnson, S.M.1
Gulhati, P.2
Arrieta, I.3
Wang, X.4
Uchida, T.5
Gao, T.6
Evers, B.M.7
-
101
-
-
0042169007
-
Molecular mechanisms of curcumin-induced cytotoxicity: Induction of apoptosis through generation of reactive oxygen species, downregulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt
-
Woo, J.H.; Kim, Y.H.; Choi, Y.J.; Kim, D.G.; Lee, K.S.; Bae, J.H.; Min, D.S.; Chang, J.S.; Jeong, Y.J.; Lee, Y.H.; Park, J.W.; Kwon, T.K. Molecular mechanisms of curcumin-induced cytotoxicity: Induction of apoptosis through generation of reactive oxygen species, downregulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt. Carcinogenesis 2003, 24, 1199-1208.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1199-1208
-
-
Woo, J.H.1
Kim, Y.H.2
Choi, Y.J.3
Kim, D.G.4
Lee, K.S.5
Bae, J.H.6
Min, D.S.7
Chang, J.S.8
Jeong, Y.J.9
Lee, Y.H.10
Park, J.W.11
Kwon, T.K.12
-
102
-
-
0037299799
-
Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathwa ys to induction of apoptosis by curcumin in breast cells
-
Squires, M.S.; Hudson, E.A.; Howells, L.; Sale, S.; Houghton, C.E.; Jones, J.L.; Fox, L.H.; Dickens, M.; Prigent, S.A.; Manson, M.M. Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathwa ys to induction of apoptosis by curcumin in breast cells. Biochem. Pharmacol. 2003, 65, 361-376.
-
(2003)
Biochem. Pharmacol
, vol.65
, pp. 361-376
-
-
Squires, M.S.1
Hudson, E.A.2
Howells, L.3
Sale, S.4
Houghton, C.E.5
Jones, J.L.6
Fox, L.H.7
Dickens, M.8
Prigent, S.A.9
Manson, M.M.10
-
103
-
-
79951770891
-
Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1
-
DOI: 10.1007/s12032-009-9341-6
-
Singh, M.; Pandey, A.; Karikari, C.A.; Singh, G.; Rakheja, D. Cell cycle inhibition and apoptosis induced by curcumin in Ewing sarcoma cell line SK-NEP-1. Med. Oncol. 2009, DOI: 10.1007/s12032-009-9341-6.
-
(2009)
Med. Oncol
-
-
Singh, M.1
Pandey, A.2
Karikari, C.A.3
Singh, G.4
Rakheja, D.5
-
104
-
-
54049128202
-
Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism
-
Yu, S.; Shen, G.; Khor, T.O.; Kim, J.H.; Kong, A.N. Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism. Mol. Cancer Ther. 2008, 7, 2609-2620.
-
(2008)
Mol. Cancer Ther
, vol.7
, pp. 2609-2620
-
-
Yu, S.1
Shen, G.2
Khor, T.O.3
Kim, J.H.4
Kong, A.N.5
-
105
-
-
36448981749
-
Curcumin enhances the apoptosisinducing potential of TRAIL in prostate cancer cells: Molecular mechanisms of apoptosis, migration and angiogenesis
-
Shankar, S.; Chen, Q.; Sarva, K.; Siddiqui, I.; Srivastava, R.K. Curcumin enhances the apoptosisinducing potential of TRAIL in prostate cancer cells: Molecular mechanisms of apoptosis, migration and angiogenesis. J. Mol. Signal. 2007, 2, 10.
-
(2007)
J. Mol. Signal
, vol.2
, pp. 10
-
-
Shankar, S.1
Chen, Q.2
Sarva, K.3
Siddiqui, I.4
Srivastava, R.K.5
-
106
-
-
33947270928
-
Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway
-
Li, M.; Zhang, Z.; Hill, D.L.; Wang, H.; Zhang, R. Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway. Cancer Res. 2007, 67, 1988-1996.
-
(2007)
Cancer Res
, vol.67
, pp. 1988-1996
-
-
Li, M.1
Zhang, Z.2
Hill, D.L.3
Wang, H.4
Zhang, R.5
-
107
-
-
0037404397
-
Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells
-
Chaudhary, L.R.; Hruska, K.A. Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells. J. Cell. Biochem. 2003, 89, 1-5.
-
(2003)
J. Cell. Biochem
, vol.89
, pp. 1-5
-
-
Chaudhary, L.R.1
Hruska, K.A.2
-
108
-
-
59149091041
-
Curcumin disrupts the mammalian target of rapamycin-raptor complex
-
Beevers, C.S.; Chen, L.; Liu, L.; Luo, Y.; Webster, N.J.; Huang, S. Curcumin disrupts the mammalian target of rapamycin-raptor complex. Cancer Res. 2009, 69, 1000-1008.
-
(2009)
Cancer Res
, vol.69
, pp. 1000-1008
-
-
Beevers, C.S.1
Chen, L.2
Liu, L.3
Luo, Y.4
Webster, N.J.5
Huang, S.6
-
109
-
-
77956953252
-
Curcumin modulates eukaryotic initiation factors in human lung adenocarcinoma epithelial cells
-
DOI: 10.1007/s11033-009-9888-5
-
Chen, L.; Tian, G.; Shao, C.; Cobos, E.; Gao, W. Curcumin modulates eukaryotic initiation factors in human lung adenocarcinoma epithelial cells. Mol. Biol. Rep. 2009, DOI: 10.1007/s11033-009-9888-5.
-
(2009)
Mol. Biol. Rep
-
-
Chen, L.1
Tian, G.2
Shao, C.3
Cobos, E.4
Gao, W.5
-
110
-
-
36849021582
-
Curcumin down-regulates the multidrugresistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway
-
Choi, B.H.; Kim, C.G.; Lim, Y.; Shin, S.Y.; Lee, Y.H. Curcumin down-regulates the multidrugresistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway. Cancer Lett. 2008, 259, 111-118.
-
(2008)
Cancer Lett
, vol.259
, pp. 111-118
-
-
Choi, B.H.1
Kim, C.G.2
Lim, Y.3
Shin, S.Y.4
Lee, Y.H.5
-
111
-
-
0037902047
-
4-Hydroxy-3-methoxybenzoic acid methyl ester: A curcumin derivative targets Akt/NF kappa B cell survival signaling pathway: Potential for prostate cancer management
-
Kumar, A.P.; Garcia, G.E.; Ghosh, R.; Rajnarayanan, R.V.; Alworth, W.L.; Slaga, T.J., 4-Hydroxy-3-methoxybenzoic acid methyl ester: A curcumin derivative targets Akt/NF kappa B cell survival signaling pathway: Potential for prostate cancer management. Neoplasia 2003, 5, 255-266.
-
(2003)
Neoplasia
, vol.5
, pp. 255-266
-
-
Kumar, A.P.1
Garcia, G.E.2
Ghosh, R.3
Rajnarayanan, R.V.4
Alworth, W.L.5
Slaga, T.J.6
-
112
-
-
33646576169
-
Matrix metalloproteinases and tumor metastasis
-
Deryugina, E.I.; Quigley, J.P. Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev. 2006, 25, 9-34.
-
(2006)
Cancer Metastasis Rev
, vol.25
, pp. 9-34
-
-
Deryugina, E.I.1
Quigley, J.P.2
-
113
-
-
3042558087
-
Effect of curcumin on gelatinase A (MMP-2) activity in B16F10 melanoma cells
-
Banerji, A.; Chakrabarti, J.; Mitra, A.; Chatterjee, A. Effect of curcumin on gelatinase A (MMP-2) activity in B16F10 melanoma cells. Cancer Lett. 2004, 211, 235-242.
-
(2004)
Cancer Lett
, vol.211
, pp. 235-242
-
-
Banerji, A.1
Chakrabarti, J.2
Mitra, A.3
Chatterjee, A.4
-
114
-
-
3342920596
-
Curcumin inhibits cell motility and alters microfilament organization and function in prostate cancer cells
-
Holy, J. Curcumin inhibits cell motility and alters microfilament organization and function in prostate cancer cells. Cell Motil. Cytoskeleton 2004, 58, 253-268.
-
(2004)
Cell Motil. Cytoskeleton
, vol.58
, pp. 253-268
-
-
Holy, J.1
-
115
-
-
33745660306
-
The effects of curcumin on the invasiveness of prostate cancer in vitro and in vivo
-
Hong, J.H.; Ahn, K.S.; Bae, E.; Jeon, S.S.; Choi, H.Y. The effects of curcumin on the invasiveness of prostate cancer in vitro and in vivo. Prostate Cancer Prostatic Dis. 2006, 9, 147-152.
-
(2006)
Prostate Cancer Prostatic Dis
, vol.9
, pp. 147-152
-
-
Hong, J.H.1
Ahn, K.S.2
Bae, E.3
Jeon, S.S.4
Choi, H.Y.5
-
116
-
-
70349970838
-
Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF)
-
Lin, S.S.; Lai, K.C.; Hsu, S.C.; Yang, J.S.; Kuo, C.L.; Lin, J.P.; Ma, Y.S.; Wu, C.C.; Chung, J.G. Curcumin inhibits the migration and invasion of human A549 lung cancer cells through the inhibition of matrix metalloproteinase-2 and -9 and Vascular Endothelial Growth Factor (VEGF). Cancer Lett. 2009, 285, 127-133.
-
(2009)
Cancer Lett
, vol.285
, pp. 127-133
-
-
Lin, S.S.1
Lai, K.C.2
Hsu, S.C.3
Yang, J.S.4
Kuo, C.L.5
Lin, J.P.6
Ma, Y.S.7
Wu, C.C.8
Chung, J.G.9
-
117
-
-
27144468987
-
Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice
-
Aggarwal, B.B.; Shishodia, S.; Takada, Y.; Banerjee, S.; Newman, R.A.; Bueso-Ramos, C.E.; Price, J.E. Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB pathway in breast cancer cells and inhibits lung metastasis of human breast cancer in nude mice. Clin. Cancer Res. 2005, 11, 7490-7498.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 7490-7498
-
-
Aggarwal, B.B.1
Shishodia, S.2
Takada, Y.3
Banerjee, S.4
Newman, R.A.5
Bueso-Ramos, C.E.6
Price, J.E.7
-
118
-
-
69849091814
-
Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFkappaB, cyclinD and MMP-1 transcription
-
Liu, Q.; Loo, W.T.; Sze, S.C.; Tong, Y. Curcumin inhibits cell proliferation of MDA-MB-231 and BT-483 breast cancer cells mediated by down-regulation of NFkappaB, cyclinD and MMP-1 transcription. Phytomedicine 2009, 16, 916-922.
-
(2009)
Phytomedicine
, vol.16
, pp. 916-922
-
-
Liu, Q.1
Loo, W.T.2
Sze, S.C.3
Tong, Y.4
-
119
-
-
7144227965
-
Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials
-
Voldborg, B.R.; Damstrup, L.; Spang-Thomsen, M.; Poulsen, H.S. Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials. Ann. Oncol. 1997, 8, 1197-1206.
-
(1997)
Ann. Oncol
, vol.8
, pp. 1197-1206
-
-
Voldborg, B.R.1
Damstrup, L.2
Spang-Thomsen, M.3
Poulsen, H.S.4
-
120
-
-
74549114727
-
Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer
-
DOI: 10.1111/j.1742-4658.2009.07 448.x
-
Mitsudomi, T.; Yatabe, Y. Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer. FEBS J. 2009, DOI: 10.1111/j.1742-4658.2009.07 448.x.
-
(2009)
FEBS J
-
-
Mitsudomi, T.1
Yatabe, Y.2
-
121
-
-
0028556758
-
Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells
-
Korutla, L.; Kumar, R. Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells. Biochim. Biophys. Acta 1994, 1224, 597-600.
-
(1994)
Biochim. Biophys. Acta
, vol.1224
, pp. 597-600
-
-
Korutla, L.1
Kumar, R.2
-
122
-
-
79151481328
-
Mechanisms for the activity of heterocyclic cyclohexanone curcumin derivatives in estrogen receptor negative human breast cancer cell lines
-
DOI: 10.1007/s10637-009-9339-0
-
Somers-Edgar, T.J.; Taurin, S.; Larsen, L.; Chandramouli, A.; Nelson, M.A.; Rosengren, R.J. Mechanisms for the activity of heterocyclic cyclohexanone curcumin derivatives in estrogen receptor negative human breast cancer cell lines. Invest. New Drug. 2009, DOI: 10.1007/s10637-009-9339-0.
-
(2009)
Invest. New Drug
-
-
Somers-Edgar, T.J.1
Taurin, S.2
Larsen, L.3
Chandramouli, A.4
Nelson, M.A.5
Rosengren, R.J.6
-
123
-
-
0034090594
-
Therapeutic potential of curcumin in human prostate cancer. II. Curcumin inhibits tyrosine kinase activity of epidermal growth factor receptor and depletes the protein
-
Dorai, T.; Gehani, N.; Katz, A., Therapeutic potential of curcumin in human prostate cancer. II. Curcumin inhibits tyrosine kinase activity of epidermal growth factor receptor and depletes the protein. Mol. Urol. 2000, 4, 1-6.
-
(2000)
Mol. Urol
, vol.4
, pp. 1-6
-
-
Dorai, T.1
Gehani, N.2
Katz, A.3
-
124
-
-
52149086304
-
Androgen responsive and refractory prostate cancer cells exhibit distinct curcumin regulated transcriptome
-
Thangapazham, R.L.; Shaheduzzaman, S.; Kim, K.H.; Passi, N.; Tadese, A.; Vahey, M.; Dobi, A.; Srivastava, S.; Maheshwari, R.K. Androgen responsive and refractory prostate cancer cells exhibit distinct curcumin regulated transcriptome. Cancer Biol. Ther. 2008, 7, 1427-1435.
-
(2008)
Cancer Biol. Ther
, vol.7
, pp. 1427-1435
-
-
Thangapazham, R.L.1
Shaheduzzaman, S.2
Kim, K.H.3
Passi, N.4
Tadese, A.5
Vahey, M.6
Dobi, A.7
Srivastava, S.8
Maheshwari, R.K.9
-
125
-
-
33750850587
-
Mechanisms of curcuminand EGF-receptor related protein (ERRP)-dependent growth inhibition of colon cancer cells
-
Reddy, S.; Rishi, A.K.; Xu, H.; Levi, E.; Sarkar, F.H.; Majumdar, A.P. Mechanisms of curcuminand EGF-receptor related protein (ERRP)-dependent growth inhibition of colon cancer cells. Nutr. Cancer 2006, 55, 185-194.
-
(2006)
Nutr. Cancer
, vol.55
, pp. 185-194
-
-
Reddy, S.1
Rishi, A.K.2
Xu, H.3
Levi, E.4
Sarkar, F.H.5
Majumdar, A.P.6
-
126
-
-
0029081718
-
Inhibition of ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation by curcumin
-
Korutla, L.; Cheung, J.Y.; Mendelsohn, J.; Kumar, R. Inhibition of ligand-induced activation of epidermal growth factor receptor tyrosine phosphorylation by curcumin. Carcinogenesis 1995, 16, 1741-1745.
-
(1995)
Carcinogenesis
, vol.16
, pp. 1741-1745
-
-
Korutla, L.1
Cheung, J.Y.2
Mendelsohn, J.3
Kumar, R.4
-
127
-
-
13844306722
-
Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR
-
Chen, A.; Xu, J. Activation of PPAR{gamma} by curcumin inhibits Moser cell growth and mediates suppression of gene expression of cyclin D1 and EGFR. Am. J. Physiol. Gastrointest. Liver Physiol. 2005, 288, G447-G456.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.288
-
-
Chen, A.1
Xu, J.2
-
128
-
-
33644869673
-
Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin
-
Kim, J.H.; Xu, C.; Keum, Y.S.; Reddy, B.; Conney, A.; Kong, A.N. Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin. Carcinogenesis 2006, 27, 475-482.
-
(2006)
Carcinogenesis
, vol.27
, pp. 475-482
-
-
Kim, J.H.1
Xu, C.2
Keum, Y.S.3
Reddy, B.4
Conney, A.5
Kong, A.N.6
-
129
-
-
30544439107
-
Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1
-
Chen, A.; Xu, J.; Johnson, A.C. Curcumin inhibits human colon cancer cell growth by suppressing gene expression of epidermal growth factor receptor through reducing the activity of the transcription factor Egr-1. Oncogene 2006, 25, 278-287.
-
(2006)
Oncogene
, vol.25
, pp. 278-287
-
-
Chen, A.1
Xu, J.2
Johnson, A.C.3
-
130
-
-
0031840433
-
Curcumin is an in vivo inhibitor of angiogenesis
-
Arbiser, J.L.; Klauber, N.; Rohan, R.; van Leeuwen, R.; Huang, M.T.; Fisher, C.; Flynn, E.; Byers, H.R. Curcumin is an in vivo inhibitor of angiogenesis. Mol. Med. 1998, 4, 376-383.
-
(1998)
Mol. Med
, vol.4
, pp. 376-383
-
-
Arbiser, J.L.1
Klauber, N.2
Rohan, R.3
van Leeuwen, R.4
Huang, M.T.5
Fisher, C.6
Flynn, E.7
Byers, H.R.8
-
131
-
-
0036033449
-
Molecular mechanisms of anti-angiogenic effect of curcumin
-
Gururaj, A.E.; Belakavadi, M.; Venkatesh, D.A.; Marme, D.; Salimath, B.P. Molecular mechanisms of anti-angiogenic effect of curcumin. Biochem. Biophys. Res. Commun. 2002, 297, 934-942.
-
(2002)
Biochem. Biophys. Res. Commun
, vol.297
, pp. 934-942
-
-
Gururaj, A.E.1
Belakavadi, M.2
Venkatesh, D.A.3
Marme, D.4
Salimath, B.P.5
-
132
-
-
84934438047
-
Curcumin as an inhibitor of angiogenesis
-
Bhandarkar, S.S.; Arbiser, J.L. Curcumin as an inhibitor of angiogenesis. Adv. Exp. Med. Biol. 2007, 595, 185-195.
-
(2007)
Adv. Exp. Med. Biol
, vol.595
, pp. 185-195
-
-
Bhandarkar, S.S.1
Arbiser, J.L.2
-
133
-
-
53449094359
-
Curcumin inhibits the expression of vascular endothelial growth factor and androgen-independent prostate cancer cell line PC-3 in vitro
-
Deng, G.; Yu, J.H.; Ye, Z.Q.; Hu, Z.Q. Curcumin inhibits the expression of vascular endothelial growth factor and androgen-independent prostate cancer cell line PC-3 in vitro. Zhonghua Nan Ke Xue 2008, 14, 116-121.
-
(2008)
Zhonghua Nan Ke Xue
, vol.14
, pp. 116-121
-
-
Deng, G.1
Yu, J.H.2
Ye, Z.Q.3
Hu, Z.Q.4
-
134
-
-
71749102389
-
Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and angiogenic biomarkers
-
Tharakan, S.T.; Inamoto, T.; Sung, B.; Aggarwal, B.B.; Kamat, A.M. Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and angiogenic biomarkers. Biochem. Pharmacol. 2010, 79, 218-228.
-
(2010)
Biochem. Pharmacol
, vol.79
, pp. 218-228
-
-
Tharakan, S.T.1
Inamoto, T.2
Sung, B.3
Aggarwal, B.B.4
Kamat, A.M.5
-
135
-
-
0032520716
-
Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-kappaB activation
-
Kumar, A.; Dhawan, S.; Hardegen, N.J.; Aggarwal, B.B. Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-kappaB activation. Biochem. Pharmacol. 1998, 55, 775-783.
-
(1998)
Biochem. Pharmacol
, vol.55
, pp. 775-783
-
-
Kumar, A.1
Dhawan, S.2
Hardegen, N.J.3
Aggarwal, B.B.4
-
136
-
-
44849122833
-
Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice
-
Yoysungnoen, P.; Wirachwong, P.; Changtam, C.; Suksamrarn, A.; Patumraj, S. Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice. World J. Gastroenterol. 2008, 14, 2003-2009.
-
(2008)
World J. Gastroenterol
, vol.14
, pp. 2003-2009
-
-
Yoysungnoen, P.1
Wirachwong, P.2
Changtam, C.3
Suksamrarn, A.4
Patumraj, S.5
-
137
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim, N.W.; Piatyszek, M.A.; Prowse, K.R.; Harley, C.B.; West, M.D.; Ho, P.L.; Coviello, G.M.; Wright, W.E.; Weinrich, S.L.; Shay, J.W. Specific association of human telomerase activity with immortal cells and cancer. Science 1994, 266, 2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszek, M.A.2
Prowse, K.R.3
Harley, C.B.4
West, M.D.5
Ho, P.L.6
Coviello, G.M.7
Wright, W.E.8
Weinrich, S.L.9
Shay, J.W.10
-
138
-
-
64249123166
-
Targeting critical steps of cancer metastasis and recurrence using telomerase template antagonists
-
Dikmen, Z.G.; Ozgurtas, T.; Gryaznov, S.M.; Herbert, B.S. Targeting critical steps of cancer metastasis and recurrence using telomerase template antagonists. Biochim. Biophys. Acta 2009, 1792, 240-247.
-
(2009)
Biochim. Biophys. Acta
, vol.1792
, pp. 240-247
-
-
Dikmen, Z.G.1
Ozgurtas, T.2
Gryaznov, S.M.3
Herbert, B.S.4
-
139
-
-
64249083673
-
Targeting the telosome: Therapeutic implications
-
Folini, M.; Gandellini, P.; Zaffaroni, N. Targeting the telosome: Therapeutic implications. Biochim. Biophys. Acta 2009, 1792, 309-316.
-
(2009)
Biochim. Biophys. Acta
, vol.1792
, pp. 309-316
-
-
Folini, M.1
Gandellini, P.2
Zaffaroni, N.3
-
140
-
-
18044391665
-
Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics--current status and future prospects
-
Kelland, L.R. Overcoming the immortality of tumour cells by telomere and telomerase based cancer therapeutics--current status and future prospects. Eur. J. Cancer 2005, 41, 971-979.
-
(2005)
Eur. J. Cancer
, vol.41
, pp. 971-979
-
-
Kelland, L.R.1
-
141
-
-
33947414787
-
Curcumin-induced apoptosis in human leukemia cell HL-60 is associated with inhibition of telomerase activity
-
Mukherjee Nee Chakraborty, S.; Ghosh, U.; Bhattacharyya, N.P.; Bhattacharya, R.K.; Dey, S.; Roy, M. Curcumin-induced apoptosis in human leukemia cell HL-60 is associated with inhibition of telomerase activity. Mol. Cell. Biochem. 2007, 297, 31-39.
-
(2007)
Mol. Cell. Biochem
, vol.297
, pp. 31-39
-
-
Chakraborty, M.N.S.1
Ghosh, U.2
Bhattacharyya, N.P.3
Bhattacharya, R.K.4
Dey, S.5
Roy, M.6
-
142
-
-
64249171413
-
Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells
-
Singh, M.; Singh, N. Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells. Mol. Cell. Biochem. 2009, 325, 107-119.
-
(2009)
Mol. Cell. Biochem
, vol.325
, pp. 107-119
-
-
Singh, M.1
Singh, N.2
-
143
-
-
33751384016
-
Curcumin inhibits telomerase activity in human cancer cell lines
-
Cui, S.X.; Qu, X.J.; Xie, Y.Y.; Zhou, L.; Nakata, M.; Makuuchi, M.; Tang, W. Curcumin inhibits telomerase activity in human cancer cell lines. Int. J. Mol. Med. 2006, 18, 227-231.
-
(2006)
Int. J. Mol. Med
, vol.18
, pp. 227-231
-
-
Cui, S.X.1
Qu, X.J.2
Xie, Y.Y.3
Zhou, L.4
Nakata, M.5
Makuuchi, M.6
Tang, W.7
-
144
-
-
33646492469
-
Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells
-
Chakraborty, S.; Ghosh, U.; Bhattacharyya, N.P.; Bhattacharya, R.K.; Roy, M. Inhibition of telomerase activity and induction of apoptosis by curcumin in K-562 cells. Mutat. Res. 2006, 596, 81-90.
-
(2006)
Mutat. Res
, vol.596
, pp. 81-90
-
-
Chakraborty, S.1
Ghosh, U.2
Bhattacharyya, N.P.3
Bhattacharya, R.K.4
Roy, M.5
-
145
-
-
0037044179
-
Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line
-
Ramachandran, C.; Fonseca, H.B.; Jhabvala, P.; Escalon, E.A.; Melnick, S.J. Curcumin inhibits telomerase activity through human telomerase reverse transcritpase in MCF-7 breast cancer cell line. Cancer Lett. 2002, 184, 1-6.
-
(2002)
Cancer Lett
, vol.184
, pp. 1-6
-
-
Ramachandran, C.1
Fonseca, H.B.2
Jhabvala, P.3
Escalon, E.A.4
Melnick, S.J.5
-
146
-
-
77249158324
-
Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT
-
DOI: 10.1016/j.canlet.2009.08.026
-
Lee, J.H.; Chung, I.K. Curcumin inhibits nuclear localization of telomerase by dissociating the Hsp90 co-chaperone p23 from hTERT. Cancer Lett. 2009, DOI: 10.1016/j.canlet.2009.08.026.
-
(2009)
Cancer Lett
-
-
Lee, J.H.1
Chung, I.K.2
-
147
-
-
33847264434
-
Telomerase targeted anticancer bioactive prodrug by antisense-based approach
-
Kapoor, N.; Sharma, A.K.; Dwivedi, V.; Kumar, A.; Pati, U.; Misra, K. Telomerase targeted anticancer bioactive prodrug by antisense-based approach. Cancer Lett. 2007, 248, 245-250.
-
(2007)
Cancer Lett
, vol.248
, pp. 245-250
-
-
Kapoor, N.1
Sharma, A.K.2
Dwivedi, V.3
Kumar, A.4
Pati, U.5
Misra, K.6
-
148
-
-
71749115797
-
Epigenetics and cancer treatment
-
Kristensen, L.S.; Nielsen, H.M.; Hansen, L.L. Epigenetics and cancer treatment. Eur. J. Pharmacol. 2009, 625, 131-142.
-
(2009)
Eur. J. Pharmacol
, vol.625
, pp. 131-142
-
-
Kristensen, L.S.1
Nielsen, H.M.2
Hansen, L.L.3
-
149
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman, J.G.; Baylin, S.B., Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 2003, 349, 2042-2054.
-
(2003)
N. Engl. J. Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
150
-
-
58549094898
-
Curcumin is a potent DNA hypomethylation agent
-
Liu, Z.; Xie, Z.; Jones, W.; Pavlovicz, R.E.; Liu, S.; Yu, J.; Li, P.K.; Lin, J.; Fuchs, J.R.; Marcucci, G.; Li, C.; Chan, K.K. Curcumin is a potent DNA hypomethylation agent. Bioorg. Med. Chem. Lett. 2009, 19, 706-709.
-
(2009)
Bioorg. Med. Chem. Lett
, vol.19
, pp. 706-709
-
-
Liu, Z.1
Xie, Z.2
Jones, W.3
Pavlovicz, R.E.4
Liu, S.5
Yu, J.6
Li, P.K.7
Lin, J.8
Fuchs, J.R.9
Marcucci, G.10
Li, C.11
Chan, K.K.12
-
151
-
-
34248631385
-
The role of histone deacetylases (HDACs) in human cancer
-
Ropero, S.; Esteller, M. The role of histone deacetylases (HDACs) in human cancer. Mol. Oncol. 2007, 1, 19-25.
-
(2007)
Mol. Oncol
, vol.1
, pp. 19-25
-
-
Ropero, S.1
Esteller, M.2
-
152
-
-
15744370742
-
Curcumin-induced histone hypoacetylation: The role of reactive oxygen species
-
Kang, J.; Chen, J.; Shi, Y.; Jia, J.; Zhang, Y., Curcumin-induced histone hypoacetylation: The role of reactive oxygen species. Biochem. Pharmacol. 2005, 69, 1205-1213.
-
(2005)
Biochem. Pharmacol
, vol.69
, pp. 1205-1213
-
-
Kang, J.1
Chen, J.2
Shi, Y.3
Jia, J.4
Zhang, Y.5
-
153
-
-
33746127271
-
Curcumin is an inhibitor of p300 histone acetylatransferase
-
Marcu, M.G.; Jung, Y.J.; Lee, S.; Chung, E.J.; Lee, M.J.; Trepel, J.; Neckers, L. Curcumin is an inhibitor of p300 histone acetylatransferase. Med. Chem. 2006, 2, 169-174.
-
(2006)
Med. Chem
, vol.2
, pp. 169-174
-
-
Marcu, M.G.1
Jung, Y.J.2
Lee, S.3
Chung, E.J.4
Lee, M.J.5
Trepel, J.6
Neckers, L.7
-
154
-
-
10944243759
-
Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription
-
Balasubramanyam, K.; Varier, R.A.; Altaf, M.; Swaminathan, V.; Siddappa, N.B.; Ranga, U.; Kundu, T.K. Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. J. Biol. Chem. 2004, 279, 51163-51171.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 51163-51171
-
-
Balasubramanyam, K.1
Varier, R.A.2
Altaf, M.3
Swaminathan, V.4
Siddappa, N.B.5
Ranga, U.6
Kundu, T.K.7
-
155
-
-
73849089144
-
Hepatocyte nuclear factor-4-independent synthesis of coagulation factor VII in breast cancer cells and its inhibition by targeting selective histone acetyltransferases
-
Koizume, S.; Yokota, N.; Miyagi, E.; Hirahara, F.; Nakamura, Y.; Sakuma, Y.; Yoshida, A.; Kameda, Y.; Tsuchiya, E.; Ruf, W.; Miyagi, Y. Hepatocyte nuclear factor-4-independent synthesis of coagulation factor VII in breast cancer cells and its inhibition by targeting selective histone acetyltransferases. Mol. Cancer Res. 2009, 7, 1928-1936.
-
(2009)
Mol. Cancer Res
, vol.7
, pp. 1928-1936
-
-
Koizume, S.1
Yokota, N.2
Miyagi, E.3
Hirahara, F.4
Nakamura, Y.5
Sakuma, Y.6
Yoshida, A.7
Kameda, Y.8
Tsuchiya, E.9
Ruf, W.10
Miyagi, Y.11
-
156
-
-
67650078931
-
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies
-
Bora-Tatar, G.; Dayangac-Erden, D.; Demir, A.S.; Dalkara, S.; Yelekci, K.; Erdem-Yurter, H. Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies. Bioorg. Med. Chem. 2009, 17, 5219-5228.
-
(2009)
Bioorg. Med. Chem
, vol.17
, pp. 5219-5228
-
-
Bora-Tatar, G.1
Dayangac-Erden, D.2
Demir, A.S.3
Dalkara, S.4
Yelekci, K.5
Erdem-Yurter, H.6
-
157
-
-
36248957463
-
Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells
-
Chen, Y.; Shu, W.; Chen, W.; Wu, Q.; Liu, H.; Cui, G. Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells. Basic Clin. Pharmacol. Toxicol. 2007, 101, 427-433.
-
(2007)
Basic Clin. Pharmacol. Toxicol
, vol.101
, pp. 427-433
-
-
Chen, Y.1
Shu, W.2
Chen, W.3
Wu, Q.4
Liu, H.5
Cui, G.6
-
158
-
-
44649179545
-
MicroRNAs and cancer epigenetics
-
Fabbri, M. MicroRNAs and cancer epigenetics. Curr. Opin. Investig. Drugs 2008, 9, 583-590.
-
(2008)
Curr. Opin. Investig. Drugs
, vol.9
, pp. 583-590
-
-
Fabbri, M.1
-
159
-
-
72849147757
-
Epigenetics, miRNAs, and human cancer: A new chapter in human gene regulation
-
Valeri, N.; Vannini, I.; Fanini, F.; Calore, F.; Adair, B.; Fabbri, M. Epigenetics, miRNAs, and human cancer: A new chapter in human gene regulation. Mamm. Genome 2009, 20, 573-580.
-
(2009)
Mamm. Genome
, vol.20
, pp. 573-580
-
-
Valeri, N.1
Vannini, I.2
Fanini, F.3
Calore, F.4
Adair, B.5
Fabbri, M.6
-
160
-
-
73849092036
-
MicroRNAs and cancer epigenetics: A macrorevolution
-
Davalos, V.; Esteller, M. MicroRNAs and cancer epigenetics: A macrorevolution. Curr. Opin. Oncol. 2010, 22, 35-45.
-
(2010)
Curr. Opin. Oncol
, vol.22
, pp. 35-45
-
-
Davalos, V.1
Esteller, M.2
-
161
-
-
50849104285
-
Mechanisms of microRNA deregulation in human cancer
-
Deng, S.; Calin, G.A.; Croce, C.M.; Coukos, G.; Zhang, L. Mechanisms of microRNA deregulation in human cancer. Cell Cycle 2008, 7, 2643-2646.
-
(2008)
Cell Cycle
, vol.7
, pp. 2643-2646
-
-
Deng, S.1
Calin, G.A.2
Croce, C.M.3
Coukos, G.4
Zhang, L.5
-
162
-
-
77149174482
-
The microRNA network and tumor metastasis
-
DOI: 10.1038/onc.2009.406
-
Zhang, H.; Li, Y.; Lai, M. The microRNA network and tumor metastasis. Oncogene 2009, DOI: 10.1038/onc.2009.406.
-
(2009)
Oncogene
-
-
Zhang, H.1
Li, Y.2
Lai, M.3
-
163
-
-
48349133693
-
Evidence for dietary regulation of microRNA expression in cancer cells
-
Davis, C.D.; Ross, S.A. Evidence for dietary regulation of microRNA expression in cancer cells. Nutr. Rev. 2008, 66, 477-482.
-
(2008)
Nutr. Rev
, vol.66
, pp. 477-482
-
-
Davis, C.D.1
Ross, S.A.2
-
164
-
-
41649090153
-
Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells
-
Sun, M.; Estrov, Z.; Ji, Y.; Coombes, K.R.; Harris, D.H.; Kurzrock, R. Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells. Mol. Cancer Ther. 2008, 7, 464-473.
-
(2008)
Mol. Cancer Ther
, vol.7
, pp. 464-473
-
-
Sun, M.1
Estrov, Z.2
Ji, Y.3
Coombes, K.R.4
Harris, D.H.5
Kurzrock, R.6
-
165
-
-
79951767903
-
Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells
-
DOI: 10.1007/s12032-009-9344-3
-
Yang, J.; Cao, Y.; Sun, J.; Zhang, Y. Curcumin reduces the expression of Bcl-2 by upregulating miR-15a and miR-16 in MCF-7 cells. Med. Oncol. 2009, DOI: 10.1007/s12032-009-9344-3.
-
(2009)
Med. Oncol
-
-
Yang, J.1
Cao, Y.2
Sun, J.3
Zhang, Y.4
-
166
-
-
55949095821
-
Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells
-
Reuter, S.; Eifes, S.; Dicato, M.; Aggarwal, B.B.; Diederich, M. Modulation of anti-apoptotic and survival pathways by curcumin as a strategy to induce apoptosis in cancer cells. Biochem. Pharmacol. 2008, 76, 1340-1351.
-
(2008)
Biochem. Pharmacol
, vol.76
, pp. 1340-1351
-
-
Reuter, S.1
Eifes, S.2
Dicato, M.3
Aggarwal, B.B.4
Diederich, M.5
-
167
-
-
56249102048
-
Apoptosis and non-apoptotic deaths in cancer development and treatment response
-
de Bruin, E.C.; Medema, J.P. Apoptosis and non-apoptotic deaths in cancer development and treatment response. Cancer Treat. Rev. 2008, 34, 737-749.
-
(2008)
Cancer Treat. Rev
, vol.34
, pp. 737-749
-
-
de Bruin, E.C.1
Medema, J.P.2
-
168
-
-
33748433166
-
Curcumin activated both receptor-mediated and mitochondria-mediated proteolytic pathways for apoptosis in human glioblastoma T98G cells
-
Karmakar, S.; Banik, N.L.; Patel, S.J.; Ray, S.K. Curcumin activated both receptor-mediated and mitochondria-mediated proteolytic pathways for apoptosis in human glioblastoma T98G cells. Neurosci. Lett. 2006, 407, 53-58.
-
(2006)
Neurosci. Lett
, vol.407
, pp. 53-58
-
-
Karmakar, S.1
Banik, N.L.2
Patel, S.J.3
Ray, S.K.4
-
169
-
-
34547657453
-
Curcumin induces apoptosis through mitochondrial hyperpolarization and mtDNA damage in human hepatoma G2 cells
-
Cao, J.; Liu, Y.; Jia, L.; Zhou, H.M.; Kong, Y.; Yang, G.; Jiang, L.P.; Li, Q.J.; Zhong, L.F. Curcumin induces apoptosis through mitochondrial hyperpolarization and mtDNA damage in human hepatoma G2 cells. Free Radic. Biol. Med. 2007, 43, 968-975.
-
(2007)
Free Radic. Biol. Med
, vol.43
, pp. 968-975
-
-
Cao, J.1
Liu, Y.2
Jia, L.3
Zhou, H.M.4
Kong, Y.5
Yang, G.6
Jiang, L.P.7
Li, Q.J.8
Zhong, L.F.9
-
170
-
-
30544455551
-
Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression
-
Song, G.; Mao, Y.B.; Cai, Q.F.; Yao, L.M.; Ouyang, G.L.; Bao, S.D. Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression. Braz. J. Med. Biol. Res. 2005, 38, 1791-1798.
-
(2005)
Braz. J. Med. Biol. Res
, vol.38
, pp. 1791-1798
-
-
Song, G.1
Mao, Y.B.2
Cai, Q.F.3
Yao, L.M.4
Ouyang, G.L.5
Bao, S.D.6
-
171
-
-
42749090720
-
Effects of curcumin on bladder cancer cells and development of urothelial tumors in a rat bladder carcinogenesis model
-
Tian, B.; Wang, Z.; Zhao, Y.; Wang, D.; Li, Y.; Ma, L.; Li, X.; Li, J.; Xiao, N.; Tian, J.; Rodriguez, R. Effects of curcumin on bladder cancer cells and development of urothelial tumors in a rat bladder carcinogenesis model. Cancer Lett. 2008, 264, 299-308.
-
(2008)
Cancer Lett
, vol.264
, pp. 299-308
-
-
Tian, B.1
Wang, Z.2
Zhao, Y.3
Wang, D.4
Li, Y.5
Ma, L.6
Li, X.7
Li, J.8
Xiao, N.9
Tian, J.10
Rodriguez, R.11
-
172
-
-
63149189848
-
Curcumin inhibits prosurvival pathways in chronic lymphocytic leukemia B cells and may overcome their stromal protection in combination with EGCG
-
Ghosh, A.K.; Kay, N.E.; Secreto, C.R.; Shanafelt, T.D. Curcumin inhibits prosurvival pathways in chronic lymphocytic leukemia B cells and may overcome their stromal protection in combination with EGCG. Clin. Cancer Res. 2009, 15, 1250-1258.
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 1250-1258
-
-
Ghosh, A.K.1
Kay, N.E.2
Secreto, C.R.3
Shanafelt, T.D.4
-
173
-
-
0036195104
-
Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: Its suppression by ectopic expression of Bcl-2 and Bcl-xl
-
Anto, R.J.; Mukhopadhyay, A.; Denning, K.; Aggarwal, B.B. Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: Its suppression by ectopic expression of Bcl-2 and Bcl-xl. Carcinogenesis 2002, 23, 143-150.
-
(2002)
Carcinogenesis
, vol.23
, pp. 143-150
-
-
Anto, R.J.1
Mukhopadhyay, A.2
Denning, K.3
Aggarwal, B.B.4
-
174
-
-
0035842333
-
Curcumin induces apoptosis in human melanoma cells through a Fasreceptor/caspase-8 pathway independent of p53
-
Bush, J.A.; Cheung, K.J., Jr.; Li, G. Curcumin induces apoptosis in human melanoma cells through a Fasreceptor/caspase-8 pathway independent of p53. Exp. Cell. Res. 2001, 271, 305-314.
-
(2001)
Exp. Cell. Res
, vol.271
, pp. 305-314
-
-
Bush, J.A.1
Cheung Jr., K.J.2
Li, G.3
-
175
-
-
0035002201
-
Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells
-
Moragoda, L.; Jaszewski, R.; Majumdar, A.P. Curcumin induced modulation of cell cycle and apoptosis in gastric and colon cancer cells. Anticancer Res. 2001, 21, 873-878.
-
(2001)
Anticancer Res
, vol.21
, pp. 873-878
-
-
Moragoda, L.1
Jaszewski, R.2
Majumdar, A.P.3
-
176
-
-
67249125471
-
Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells
-
Friedman, L.; Lin, L.; Ball, S.; Bekaii-Saab, T.; Fuchs, J.; Li, P.K.; Li, C.; Lin, J. Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells. Anticancer Drug. 2009, 20, 444-449.
-
(2009)
Anticancer Drug
, vol.20
, pp. 444-449
-
-
Friedman, L.1
Lin, L.2
Ball, S.3
Bekaii-Saab, T.4
Fuchs, J.5
Li, P.K.6
Li, C.7
Lin, J.8
-
177
-
-
16844371915
-
Induction of apoptosis by curcumin and its implications for cancer therapy
-
Karunagaran, D.; Rashmi, R.; Kumar, T.R. Induction of apoptosis by curcumin and its implications for cancer therapy. Curr. Cancer Drug Targets 2005, 5, 117-129.
-
(2005)
Curr. Cancer Drug Targets
, vol.5
, pp. 117-129
-
-
Karunagaran, D.1
Rashmi, R.2
Kumar, T.R.3
-
178
-
-
3042537050
-
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy
-
Castedo, M.; Perfettini, J.L.; Roumier, T.; Valent, A.; Raslova, H.; Yakushijin, K.; Horne, D.; Feunteun, J.; Lenoir, G.; Medema, R.; Vainchenker, W.; Kroemer, G. Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy. Oncogene 2004, 23, 4362-4370.
-
(2004)
Oncogene
, vol.23
, pp. 4362-4370
-
-
Castedo, M.1
Perfettini, J.L.2
Roumier, T.3
Valent, A.4
Raslova, H.5
Yakushijin, K.6
Horne, D.7
Feunteun, J.8
Lenoir, G.9
Medema, R.10
Vainchenker, W.11
Kroemer, G.12
-
179
-
-
2342635919
-
Cell death by mitotic catastrophe: A molecular definition
-
Castedo, M.; Perfettini, J.L.; Roumier, T.; Andreau, K.; Medema, R.; Kroemer, G. Cell death by mitotic catastrophe: A molecular definition. Oncogene 2004, 23, 2825-2837.
-
(2004)
Oncogene
, vol.23
, pp. 2825-2837
-
-
Castedo, M.1
Perfettini, J.L.2
Roumier, T.3
Andreau, K.4
Medema, R.5
Kroemer, G.6
-
180
-
-
0035736138
-
If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells
-
Roninson, I.B.; Broude, E.V.; Chang, B.D. If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist. Update. 2001, 4, 303-313.
-
(2001)
Drug Resist. Update
, vol.4
, pp. 303-313
-
-
Roninson, I.B.1
Broude, E.V.2
Chang, B.D.3
-
181
-
-
0037182806
-
Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells
-
Holy, J.M. Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells. Mutat. Res. 2002, 518, 71-84.
-
(2002)
Mutat. Res
, vol.518
, pp. 71-84
-
-
Holy, J.M.1
-
182
-
-
33748207614
-
Resistance to apoptosis of HCW-2 cells can be overcome by curcumin- or vincristine-induced mitotic catastrophe
-
Magalska, A.; Sliwinska, M.; Szczepanowska, J.; Salvioli, S.; Franceschi, C.; Sikora, E. Resistance to apoptosis of HCW-2 cells can be overcome by curcumin- or vincristine-induced mitotic catastrophe. Int. J. Cancer 2006, 119, 1811-1818.
-
(2006)
Int. J. Cancer
, vol.119
, pp. 1811-1818
-
-
Magalska, A.1
Sliwinska, M.2
Szczepanowska, J.3
Salvioli, S.4
Franceschi, C.5
Sikora, E.6
-
183
-
-
33746900778
-
Curcumin affects components of the chromosomal passenger complex and induces mitotic catastrophe in apoptosis-resistant Bcr-Abl-expressing cells
-
Wolanin, K.; Magalska, A.; Mosieniak, G.; Klinger, R.; McKenna, S.; Vejda, S.; Sikora, E.; Piwocka, K. Curcumin affects components of the chromosomal passenger complex and induces mitotic catastrophe in apoptosis-resistant Bcr-Abl-expressing cells. Mol. Cancer Res. 2006, 4, 457-469.
-
(2006)
Mol. Cancer Res
, vol.4
, pp. 457-469
-
-
Wolanin, K.1
Magalska, A.2
Mosieniak, G.3
Klinger, R.4
McKenna, S.5
Vejda, S.6
Sikora, E.7
Piwocka, K.8
-
184
-
-
70350638927
-
Curcumin induces apoptosis-independent death in oesophageal cancer cells
-
O'Sullivan-Coyne, G.; O'Sullivan, G.C.; O'Donovan, T.R.; Piwocka, K.; McKenna, S.L. Curcumin induces apoptosis-independent death in oesophageal cancer cells. Br. J. Cancer 2009, 101, 1585-1595.
-
(2009)
Br. J. Cancer
, vol.101
, pp. 1585-1595
-
-
O'sullivan-Coyne, G.1
O'Sullivan, G.C.2
O'Donovan, T.R.3
Piwocka, K.4
McKenna, S.L.5
-
185
-
-
54949127149
-
Metabolism of curcumin and induction of mitotic catastrophe in human cancer cells
-
Dempe, J.S.; Pfeiffer, E.; Grimm, A.S.; Metzler, M. Metabolism of curcumin and induction of mitotic catastrophe in human cancer cells. Mol. Nutr. Food Res. 2008, 52, 1074-1081.
-
(2008)
Mol. Nutr. Food Res
, vol.52
, pp. 1074-1081
-
-
Dempe, J.S.1
Pfeiffer, E.2
Grimm, A.S.3
Metzler, M.4
-
186
-
-
70349467857
-
Curcumin derivatives: Molecular basis of their anti-cancer activity
-
Basile, V.; Ferrari, E.; Lazzari, S.; Belluti, S.; Pignedoli, F.; Imbriano, C. Curcumin derivatives: Molecular basis of their anti-cancer activity. Biochem. Pharmacol. 2009, 78, 1305-1315.
-
(2009)
Biochem. Pharmacol
, vol.78
, pp. 1305-1315
-
-
Basile, V.1
Ferrari, E.2
Lazzari, S.3
Belluti, S.4
Pignedoli, F.5
Imbriano, C.6
-
188
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
Kondo, Y.; Kanzawa, T.; Sawaya, R.; Kondo, S. The role of autophagy in cancer development and response to therapy. Nat. Rev. Cancer 2005, 5, 726-734.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
-
189
-
-
69349087479
-
Anti- and pro-tumor functions of autophagy
-
Morselli, E.; Galluzzi, L.; Kepp, O.; Vicencio, J.M.; Criollo, A.; Maiuri, M.C.; Kroemer, G. Anti- and pro-tumor functions of autophagy. Biochim. Biophys. Acta 2009, 1793, 1524-1532.
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, pp. 1524-1532
-
-
Morselli, E.1
Galluzzi, L.2
Kepp, O.3
Vicencio, J.M.4
Criollo, A.5
Maiuri, M.C.6
Kroemer, G.7
-
190
-
-
34347238938
-
Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: Role of Akt and extracellular signal-regulated kinase signaling pathways
-
Aoki, H.; Takada, Y.; Kondo, S.; Sawaya, R.; Aggarwal, B.B.; Kondo, Y. Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: Role of Akt and extracellular signal-regulated kinase signaling pathways. Mol. Pharmacol. 2007, 72, 29-39.
-
(2007)
Mol. Pharmacol
, vol.72
, pp. 29-39
-
-
Aoki, H.1
Takada, Y.2
Kondo, S.3
Sawaya, R.4
Aggarwal, B.B.5
Kondo, Y.6
-
191
-
-
35848938724
-
Roles of the Akt/mTOR/p70S6K and ERK1/2 signaling pathways in curcumin-induced autophagy
-
Shinojima, N.; Yokoyama, T.; Kondo, Y.; Kondo, S. Roles of the Akt/mTOR/p70S6K and ERK1/2 signaling pathways in curcumin-induced autophagy. Autophagy 2007, 3, 635-637.
-
(2007)
Autophagy
, vol.3
, pp. 635-637
-
-
Shinojima, N.1
Yokoyama, T.2
Kondo, Y.3
Kondo, S.4
-
192
-
-
0031589212
-
Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides
-
Verma, S.P.; Salamone, E.; Goldin, B. Curcumin and genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides. Biochem. Biophys. Res. Commun. 1997, 233, 692-696.
-
(1997)
Biochem. Biophys. Res. Commun
, vol.233
, pp. 692-696
-
-
Verma, S.P.1
Salamone, E.2
Goldin, B.3
-
193
-
-
0030624235
-
Synergistic effects of curcumin on all-trans retinoic acid- and 1 alpha,25-dihydroxyvitamin D3-induced differentiation in human promyelocytic leukemia HL-60 cells
-
Liu, Y.; Chang, R.L.; Cui, X.X.; Newmark, H.L.; Conney, A.H. Synergistic effects of curcumin on all-trans retinoic acid- and 1 alpha,25-dihydroxyvitamin D3-induced differentiation in human promyelocytic leukemia HL-60 cells. Oncol. Res. 1997, 9, 19-29.
-
(1997)
Oncol. Res
, vol.9
, pp. 19-29
-
-
Liu, Y.1
Chang, R.L.2
Cui, X.X.3
Newmark, H.L.4
Conney, A.H.5
-
194
-
-
33746904368
-
Curcumin abolishes apoptosis resistance of calcitriol-differentiated HL-60 cells
-
Mosieniak, G.; Sliwinska, M.; Piwocka, K.; Sikora, E. Curcumin abolishes apoptosis resistance of calcitriol-differentiated HL-60 cells. FEBS Lett. 2006, 580, 4653-4660.
-
(2006)
FEBS Lett
, vol.580
, pp. 4653-4660
-
-
Mosieniak, G.1
Sliwinska, M.2
Piwocka, K.3
Sikora, E.4
-
195
-
-
33745907263
-
Effects of administration of embelin and curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during Nnitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats
-
Sreepriya, M.; Bali, G. Effects of administration of embelin and curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during Nnitrosodiethylamine/Phenobarbital-induced hepatocarcinogenesis in Wistar rats. Mol. Cell. Biochem. 2006, 284, 49-55.
-
(2006)
Mol. Cell. Biochem
, vol.284
, pp. 49-55
-
-
Sreepriya, M.1
Bali, G.2
-
196
-
-
31544454684
-
Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice
-
Khor, T.O.; Keum, Y.S.; Lin, W.; Kim, J.H.; Hu, R.; Shen, G.; Xu, C.; Gopalakrishnan, A.; Reddy, B.; Zheng, X.; Conney, A.H.; Kong, A.N. Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice. Cancer Res. 2006, 66, 613-621.
-
(2006)
Cancer Res
, vol.66
, pp. 613-621
-
-
Khor, T.O.1
Keum, Y.S.2
Lin, W.3
Kim, J.H.4
Hu, R.5
Shen, G.6
Xu, C.7
Gopalakrishnan, A.8
Reddy, B.9
Zheng, X.10
Conney, A.H.11
Kong, A.N.12
-
197
-
-
70449640434
-
Curcumin synergizes with resveratrol to inhibit colon cancer
-
Majumdar, A.P.; Banerjee, S.; Nautiyal, J.; Patel, B.B.; Patel, V.; Du, J.; Yu, Y.; Elliott, A.A.; Levi, E.; Sarkar, F.H., Curcumin synergizes with resveratrol to inhibit colon cancer. Nutr. Cancer 2009, 61, 544-553.
-
(2009)
Nutr. Cancer
, vol.61
, pp. 544-553
-
-
Majumdar, A.P.1
Banerjee, S.2
Nautiyal, J.3
Patel, B.B.4
Patel, V.5
Du, J.6
Yu, Y.7
Elliott, A.A.8
Levi, E.9
Sarkar, F.H.10
-
198
-
-
0031927214
-
Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells
-
Khafif, A.; Schantz, S.P.; Chou, T.C.; Edelstein, D.; Sacks, P.G. Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells. Carcinogenesis 1998, 19, 419-424.
-
(1998)
Carcinogenesis
, vol.19
, pp. 419-424
-
-
Khafif, A.1
Schantz, S.P.2
Chou, T.C.3
Edelstein, D.4
Sacks, P.G.5
-
199
-
-
33746353391
-
Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis
-
Cruz-Correa, M.; Shoskes, D.A.; Sanchez, P.; Zhao, R.; Hylind, L.M.; Wexner, S.D.; Giardiello, F.M. Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis. Clin. Gastroenterol. Hepatol. 2006, 4, 1035-1038.
-
(2006)
Clin. Gastroenterol. Hepatol
, vol.4
, pp. 1035-1038
-
-
Cruz-Correa, M.1
Shoskes, D.A.2
Sanchez, P.3
Zhao, R.4
Hylind, L.M.5
Wexner, S.D.6
Giardiello, F.M.7
-
200
-
-
1542426626
-
Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3
-
Chendil, D.; Ranga, R.S.; Meigooni, D.; Sathishkumar, S.; Ahmed, M.M. Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3. Oncogene 2004, 23, 1599-1607.
-
(2004)
Oncogene
, vol.23
, pp. 1599-1607
-
-
Chendil, D.1
Ranga, R.S.2
Meigooni, D.3
Sathishkumar, S.4
Ahmed, M.M.5
-
201
-
-
42449117212
-
The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway
-
Javvadi, P.; Segan, A.T.; Tuttle, S.W.; Koumenis, C. The chemopreventive agent curcumin is a potent radiosensitizer of human cervical tumor cells via increased reactive oxygen species production and overactivation of the mitogen-activated protein kinase pathway. Mol. Pharmacol. 2008, 73, 1491-1501.
-
(2008)
Mol. Pharmacol
, vol.73
, pp. 1491-1501
-
-
Javvadi, P.1
Segan, A.T.2
Tuttle, S.W.3
Koumenis, C.4
-
202
-
-
14844303304
-
Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-kappaB and the serine/threonine kinase Akt and is independent of tubulin polymerization
-
Bava, S.V.; Puliappadamba, V.T.; Deepti, A.; Nair, A.; Karunagaran, D.; Anto, R.J. Sensitization of taxol-induced apoptosis by curcumin involves down-regulation of nuclear factor-kappaB and the serine/threonine kinase Akt and is independent of tubulin polymerization. J. Biol. Chem. 2005, 280, 6301-6308.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 6301-6308
-
-
Bava, S.V.1
Puliappadamba, V.T.2
Deepti, A.3
Nair, A.4
Karunagaran, D.5
Anto, R.J.6
-
203
-
-
65549122576
-
Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB in breast cancer cells and potentiates the growth inhibitory effect of paclitax el in a breast cancer nude mice model
-
Kang, H.J.; Lee, S.H.; Price, J.E.; Kim, L.S. Curcumin suppresses the paclitaxel-induced nuclear factor-kappaB in breast cancer cells and potentiates the growth inhibitory effect of paclitax el in a breast cancer nude mice model. Breast J. 2009, 15, 223-229.
-
(2009)
Breast J
, vol.15
, pp. 223-229
-
-
Kang, H.J.1
Lee, S.H.2
Price, J.E.3
Kim, L.S.4
-
204
-
-
18844461634
-
Curcumin enhances Vinorelbine mediated apoptosis in NSCLC cells by the mitochondrial pathway
-
Sen, S.; Sharma, H.; Singh, N. Curcumin enhances Vinorelbine mediated apoptosis in NSCLC cells by the mitochondrial pathway. Biochem. Biophys. Res. Commun. 2005, 331, 1245-1252.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.331
, pp. 1245-1252
-
-
Sen, S.1
Sharma, H.2
Singh, N.3
-
205
-
-
25144513892
-
Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells
-
Lev-Ari, S.; Strier, L.; Kazanov, D.; Madar-Shapiro, L.; Dvory-Sobol, H.; Pinchuk, I.; Marian, B.; Lichtenberg, D.; Arber, N. Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells. Clin. Cancer Res. 2005, 11, 6738-6744.
-
(2005)
Clin. Cancer Res
, vol.11
, pp. 6738-6744
-
-
Lev-Ari, S.1
Strier, L.2
Kazanov, D.3
Madar-Shapiro, L.4
Dvory-Sobol, H.5
Pinchuk, I.6
Marian, B.7
Lichtenberg, D.8
Arber, N.9
-
206
-
-
31544471349
-
Curcumin synergistically potentiates the growth inhibitory and pro-apoptotic effects of celecoxib in pancreatic adenocarcinoma cells
-
Lev-Ari, S.; Zinger, H.; Kazanov, D.; Yona, D.; Ben-Yosef, R.; Starr, A.; Figer, A.; Arber, N. Curcumin synergistically potentiates the growth inhibitory and pro-apoptotic effects of celecoxib in pancreatic adenocarcinoma cells. Biomed. Pharmacother. 2005, 59, S276-S280.
-
(2005)
Biomed. Pharmacother
, vol.59
-
-
Lev-Ari, S.1
Zinger, H.2
Kazanov, D.3
Yona, D.4
Ben-Yosef, R.5
Starr, A.6
Figer, A.7
Arber, N.8
-
207
-
-
29344455140
-
Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29
-
Du, B.; Jiang, L.; Xia, Q.; Zhong, L. Synergistic inhibitory effects of curcumin and 5-fluorouracil on the growth of the human colon cancer cell line HT-29. Chemotherapy 2006, 52, 23-28.
-
(2006)
Chemotherapy
, vol.52
, pp. 23-28
-
-
Du, B.1
Jiang, L.2
Xia, Q.3
Zhong, L.4
-
208
-
-
3042857722
-
Curcumin inhibits the growth of AGS human gastric carcinoma cells in vitro and shows synergism with 5-fluorouracil
-
Koo, J.Y.; Kim, H.J.; Jung, K.O.; Park, K.Y. Curcumin inhibits the growth of AGS human gastric carcinoma cells in vitro and shows synergism with 5-fluorouracil. J. Med. Food 2004, 7, 117-121.
-
(2004)
J. Med. Food
, vol.7
, pp. 117-121
-
-
Koo, J.Y.1
Kim, H.J.2
Jung, K.O.3
Park, K.Y.4
-
209
-
-
36849018017
-
Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R
-
Patel, B.B.; Sengupta, R.; Qazi, S.; Vachhani, H.; Yu, Y.; Rishi, A.K.; Majumdar, A.P. Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R. Int. J. Cancer 2008, 122, 267-273.
-
(2008)
Int. J. Cancer
, vol.122
, pp. 267-273
-
-
Patel, B.B.1
Sengupta, R.2
Qazi, S.3
Vachhani, H.4
Yu, Y.5
Rishi, A.K.6
Majumdar, A.P.7
-
210
-
-
34248560905
-
Comparison of oxaliplatin- and curcumin-mediated antiproliferative effects in colorectal cell lines
-
Howells, L.M.; Mitra, A.; Manson, M.M. Comparison of oxaliplatin- and curcumin-mediated antiproliferative effects in colorectal cell lines. Int. J. Cancer 2007, 121, 175-183.
-
(2007)
Int. J. Cancer
, vol.121
, pp. 175-183
-
-
Howells, L.M.1
Mitra, A.2
Manson, M.M.3
-
211
-
-
0345256652
-
Cisplatin: Mode of cytotoxic action and molecular basis of resistance
-
Siddik, Z.H. Cisplatin: Mode of cytotoxic action and molecular basis of resistance. Oncogene 2003, 22, 7265-7279.
-
(2003)
Oncogene
, vol.22
, pp. 7265-7279
-
-
Siddik, Z.H.1
-
212
-
-
42749083620
-
Resistance against novel anticancer metal compounds: Differences and similarities
-
Heffeter, P.; Jungwirth, U.; Jakupec, M.; Hartinger, C.; Galanski, M.; Elbling, L.; Micksche, M.; Keppler, B.; Berger, W. Resistance against novel anticancer metal compounds: Differences and similarities. Drug Resist. Update. 2008, 11, 1-16.
-
(2008)
Drug Resist. Update
, vol.11
, pp. 1-16
-
-
Heffeter, P.1
Jungwirth, U.2
Jakupec, M.3
Hartinger, C.4
Galanski, M.5
Elbling, L.6
Micksche, M.7
Keppler, B.8
Berger, W.9
-
213
-
-
34247400267
-
Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK
-
Weir, N.M.; Selvendiran, K.; Kutala, V.K.; Tong, L.; Vishwanath, S.; Rajaram, M.; Tridandapani, S.; Anant, S.; Kuppusamy, P. Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating Akt and p38 MAPK. Cancer Biol. Ther. 2007, 6, 178-184.
-
(2007)
Cancer Biol. Ther
, vol.6
, pp. 178-184
-
-
Weir, N.M.1
Selvendiran, K.2
Kutala, V.K.3
Tong, L.4
Vishwanath, S.5
Rajaram, M.6
Tridandapani, S.7
Anant, S.8
Kuppusamy, P.9
-
214
-
-
62449102510
-
Cell-cycle inhibition and apoptosis induced by curcumin and cisplatin or oxaliplatin in human ovarian carcinoma cells
-
Montopoli, M.; Ragazzi, E.; Froldi, G.; Caparrotta, L. Cell-cycle inhibition and apoptosis induced by curcumin and cisplatin or oxaliplatin in human ovarian carcinoma cells. Cell Prolifration 2009, 42, 195-206.
-
(2009)
Cell Prolifration
, vol.42
, pp. 195-206
-
-
Montopoli, M.1
Ragazzi, E.2
Froldi, G.3
Caparrotta, L.4
-
215
-
-
67649976963
-
Curcumin sensitizes lung cancer cells to cisplatin-induced apoptosis through superoxide anion-mediated Bcl-2 degradation
-
Chanvorachote, P.; Pongrakhananon, V.; Wannachaiyasit, S.; Luanpitpong, S.; Rojanasakul, Y.; Nimmannit, U. Curcumin sensitizes lung cancer cells to cisplatin-induced apoptosis through superoxide anion-mediated Bcl-2 degradation. Cancer Invest. 2009, 27, 624-635.
-
(2009)
Cancer Invest
, vol.27
, pp. 624-635
-
-
Chanvorachote, P.1
Pongrakhananon, V.2
Wannachaiyasit, S.3
Luanpitpong, S.4
Rojanasakul, Y.5
Nimmannit, U.6
-
216
-
-
18744364422
-
Inhibition of growth and sensitization to cisplatin-mediated killing of ovarian cancer cells by polyphenoli c chemopreventive agents
-
Chan, M.M.; Fong, D.; Soprano, K. J.; Holmes, W.F.; Heverling, H. Inhibition of growth and sensitization to cisplatin-mediated killing of ovarian cancer cells by polyphenoli c chemopreventive agents. J. Cell. Physiol. 2003, 194, 63-70.
-
(2003)
J. Cell. Physiol
, vol.194
, pp. 63-70
-
-
Chan, M.M.1
Fong, D.2
Soprano, K.J.3
Holmes, W.F.4
Heverling, H.5
-
217
-
-
77953272360
-
Elimination of colon cancer stem-like cells by the combination of curcumin and FOLFOX
-
Yu, Y.; Kanwar, S.S.; Patel, B.B.; Nautiyal, J.; Sarkar, F.H.; Majumdar, A.P. Elimination of colon cancer stem-like cells by the combination of curcumin and FOLFOX. Transl. Oncol. 2009, 2, 321-328.
-
(2009)
Transl. Oncol
, vol.2
, pp. 321-328
-
-
Yu, Y.1
Kanwar, S.S.2
Patel, B.B.3
Nautiyal, J.4
Sarkar, F.H.5
Majumdar, A.P.6
-
218
-
-
66449104640
-
Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model
-
Sung, B.; Kunnumakkara, A.B.; Sethi, G.; Anand, P.; Guha, S.; Aggarwal, B.B. Curcumin circumvents chemoresistance in vitro and potentiates the effect of thalidomide and bortezomib against human multiple myeloma in nude mice model. Mol. Cancer Ther. 2009, 8, 959-970.
-
(2009)
Mol. Cancer Ther
, vol.8
, pp. 959-970
-
-
Sung, B.1
Kunnumakkara, A.B.2
Sethi, G.3
Anand, P.4
Guha, S.5
Aggarwal, B.B.6
-
219
-
-
0031801988
-
Curcumin attenuation of acute adriamycin myocardial toxicity in rats
-
Venkatesan, N. Curcumin attenuation of acute adriamycin myocardial toxicity in rats. Br. J. Pharmacol. 1998, 124, 425-427.
-
(1998)
Br. J. Pharmacol
, vol.124
, pp. 425-427
-
-
Venkatesan, N.1
-
220
-
-
77954160638
-
Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer
-
Epub ahead of print
-
Bayet-Robert, M.; Kwiatkowski, F.; Leheurteur, M.; Gachon, F.; Planchat, E.; Abrial, C.; Mouret-Reynier, M.A.; Durando, X.; Barthomeuf, C.; Chollet, P. Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer. Cancer Biol. Ther. 2010, 9, Epub ahead of print.
-
(2010)
Cancer Biol. Ther
, vol.9
-
-
Bayet-Robert, M.1
Kwiatkowski, F.2
Leheurteur, M.3
Gachon, F.4
Planchat, E.5
Abrial, C.6
Mouret-Reynier, M.A.7
Durando, X.8
Barthomeuf, C.9
Chollet, P.10
-
221
-
-
4444294803
-
Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation
-
Deeb, D.; Jiang, H.; Gao, X.; Hafner, M.S.; Wong, H.; Divine, G.; Chapman, R.A.; Dulchavsky, S.A.; Gautam, S.C. Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand/Apo2L by inhibiting nuclear factor-kappaB through suppression of IkappaBalpha phosphorylation. Mol. Cancer Ther. 2004, 3, 803-812.
-
(2004)
Mol. Cancer Ther
, vol.3
, pp. 803-812
-
-
Deeb, D.1
Jiang, H.2
Gao, X.3
Hafner, M.S.4
Wong, H.5
Divine, G.6
Chapman, R.A.7
Dulchavsky, S.A.8
Gautam, S.C.9
-
222
-
-
0042710263
-
Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells
-
Deeb, D.; Xu, Y.X.; Jiang, H.; Gao, X.; Janakiraman, N.; Chapman, R.A.; Gautam, S.C. Curcumin (diferuloyl-methane) enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in LNCaP prostate cancer cells. Mol. Cancer Ther. 2003, 2, 95-103.
-
(2003)
Mol. Cancer Ther
, vol.2
, pp. 95-103
-
-
Deeb, D.1
Xu, Y.X.2
Jiang, H.3
Gao, X.4
Janakiraman, N.5
Chapman, R.A.6
Gautam, S.C.7
-
223
-
-
28444464762
-
Chemosensitization of hormone-refractory prostate cancer cells by curcumin to TRAIL-induced apoptosis
-
Deeb, D.D.; Jiang, H.; Gao, X.; Divine, G.; Dulchavsky, S.A.; Gautam, S.C. Chemosensitization of hormone-refractory prostate cancer cells by curcumin to TRAIL-induced apoptosis. J. Exp. Ther. Oncol. 2005, 5, 81-91.
-
(2005)
J. Exp. Ther. Oncol
, vol.5
, pp. 81-91
-
-
Deeb, D.D.1
Jiang, H.2
Gao, X.3
Divine, G.4
Dulchavsky, S.A.5
Gautam, S.C.6
-
224
-
-
61449198651
-
Therapeutic efficacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer
-
Andrzejewski, T.; Deeb, D.; Gao, X.; Danyluk, A.; Arbab, A.S.; Dulchavsky, S.A.; Gautam, S.C. Therapeutic efficacy of curcumin/TRAIL combination regimen for hormone-refractory prostate cancer. Oncol. Res. 2008, 17, 257-267.
-
(2008)
Oncol. Res
, vol.17
, pp. 257-267
-
-
Andrzejewski, T.1
Deeb, D.2
Gao, X.3
Danyluk, A.4
Arbab, A.S.5
Dulchavsky, S.A.6
Gautam, S.C.7
-
225
-
-
39749093675
-
Curcumin sensitizes TRAIL-resistant xenografts: Molecular mechanisms of apoptosis, metastasis and angiogenesis
-
Shankar, S.; Ganapathy, S.; Chen, Q.; Srivastava, R.K. Curcumin sensitizes TRAIL-resistant xenografts: Molecular mechanisms of apoptosis, metastasis and angiogenesis. Mol. Cancer 2008, 7, 16.
-
(2008)
Mol. Cancer
, vol.7
, pp. 16
-
-
Shankar, S.1
Ganapathy, S.2
Chen, Q.3
Srivastava, R.K.4
-
226
-
-
67649407501
-
Curcumin in clinical practice: Myth or reality?
-
Mancuso, C.; Barone, E. Curcumin in clinical practice: Myth or reality? Trends Pharmacol. Sci. 2009, 30, 333-334.
-
(2009)
Trends Pharmacol. Sci
, vol.30
, pp. 333-334
-
-
Mancuso, C.1
Barone, E.2
-
227
-
-
0011208536
-
-
National Toxicology Program. NTP Toxicology and Carcinogenesis Studies of Turmeric Oleoresin (CAS No. 8024-37-1) (Major Component 79%-85% Curcumin, CAS No. 458-37-7) in F344/N Rats and B6C3F1 Mice (Feed Studies)
-
National Toxicology Program. NTP Toxicology and Carcinogenesis Studies of Turmeric Oleoresin (CAS No. 8024-37-1) (Major Component 79%-85% Curcumin, CAS No. 458-37-7) in F344/N Rats and B6C3F1 Mice (Feed Studies). Natl. Toxicol. Program Tech. Rep. Ser. 1993, 427, 1-275.
-
(1993)
Natl. Toxicol. Program Tech. Rep. Ser
, vol.427
, pp. 1-275
-
-
-
228
-
-
66749167590
-
Lung tumor promotion by curcumin
-
Dance-Barnes, S.T.; Kock, N.D.; Moore, J.E.; Lin, E.Y.; Mosley, L.J.; D'Agostino, R.B., Jr.; McCoy, T.P.; Townsend, A.J.; Miller, M.S. Lung tumor promotion by curcumin. Carcinogenesis 2009, 30, 1016-1023.
-
(2009)
Carcinogenesis
, vol.30
, pp. 1016-1023
-
-
Dance-Barnes, S.T.1
Kock, N.D.2
Moore, J.E.3
Lin, E.Y.4
Mosley, L.J.5
D'agostino Jr., R.B.6
McCoy, T.P.7
Townsend, A.J.8
Miller, M.S.9
-
229
-
-
4544383470
-
Curcumin impairs tumor suppressor p53 function in colon cancer cells
-
Moos, P.J.; Edes, K.; Mullally, J.E.; Fitzpatrick, F.A. Curcumin impairs tumor suppressor p53 function in colon cancer cells. Carcinogenesis 2004, 25, 1611-1617.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1611-1617
-
-
Moos, P.J.1
Edes, K.2
Mullally, J.E.3
Fitzpatrick, F.A.4
-
230
-
-
53449094405
-
Anticancer and carcinogenic properties of curcumin: Considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent
-
Lopez-Lazaro, M. Anticancer and carcinogenic properties of curcumin: Considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent. Mol. Nutr. Food Res. 2008, 52, S103-S127.
-
(2008)
Mol. Nutr. Food Res
, vol.52
-
-
Lopez-Lazaro, M.1
-
231
-
-
58849102674
-
Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator
-
Jiao, Y.; Wilkinson, J.T.; Di, X.; Wang, W.; Hatcher, H.; Kock, N.D.; D'Agostino, R., Jr.; Knovich, M.A.; Torti, F.M.; Torti, S.V. Curcumin, a cancer chemopreventive and chemotherapeutic agent, is a biologically active iron chelator. Blood 2009, 113, 462-469.
-
(2009)
Blood
, vol.113
, pp. 462-469
-
-
Jiao, Y.1
Wilkinson, J.T.2
Di, X.3
Wang, W.4
Hatcher, H.5
Kock, N.D.6
D'agostino Jr., R.7
Knovich, M.A.8
Torti, F.M.9
Torti, S.V.10
-
232
-
-
0025113795
-
Sister chromatid exchange and chromosome aberrations induced by curcumin and tartrazine on mammalian cells in vivo
-
Giri, A.K.; Das, S.K.; Talukder, G.; Sharma, A. Sister chromatid exchange and chromosome aberrations induced by curcumin and tartrazine on mammalian cells in vivo. Cytobios 1990, 62,111-117.
-
(1990)
Cytobios
, vol.62
, pp. 111-117
-
-
Giri, A.K.1
Das, S.K.2
Talukder, G.3
Sharma, A.4
-
233
-
-
33744805811
-
Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells
-
Cao, J.; Jia, L.; Zhou, H.M.; Liu, Y.; Zhong, L.F. Mitochondrial and nuclear DNA damage induced by curcumin in human hepatoma G2 cells. Toxicol. Sci. 2006, 91, 476-483.
-
(2006)
Toxicol. Sci
, vol.91
, pp. 476-483
-
-
Cao, J.1
Jia, L.2
Zhou, H.M.3
Liu, Y.4
Zhong, L.F.5
-
234
-
-
0036645522
-
Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer
-
Somasundaram, S.; Edmund, N.A.; Moore, D.T.; Small, G.W.; Shi, Y.Y.; Orlowski, R.Z. Dietary curcumin inhibits chemotherapy-induced apoptosis in models of human breast cancer. Cancer Res. 2002, 62, 3868-3875.
-
(2002)
Cancer Res
, vol.62
, pp. 3868-3875
-
-
Somasundaram, S.1
Edmund, N.A.2
Moore, D.T.3
Small, G.W.4
Shi, Y.Y.5
Orlowski, R.Z.6
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