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Volumn 38, Issue 3, 2013, Pages 651-663

The aging of the 2000 and 2011 Hallmarks of Cancer reviews: A critique

Author keywords

Oncogenes; proliferation; somatic mutation theory; stroma; tissue organization field theory

Indexed keywords

EPIDERMAL GROWTH FACTOR; NERVE GROWTH FACTOR; PROTEIN P107; PROTEIN P130; PROTEIN P53; RETINOBLASTOMA PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 84883205105     PISSN: 02505991     EISSN: 09737138     Source Type: Journal    
DOI: 10.1007/s12038-013-9335-6     Document Type: Article
Times cited : (82)

References (81)
  • 2
    • 78650354119 scopus 로고    scopus 로고
    • Model organisms and human health
    • 21177975 10.1126/science.1201826 1:CAS:528:DC%2BC3MXhtVSnu74%3D
    • Alberts B 2010 Model organisms and human health. Science 330 1724
    • (2010) Science , vol.330 , pp. 1724
    • Alberts, B.1
  • 4
    • 0014333785 scopus 로고
    • Biology as an autonomous science
    • 5684549 1:STN:280:DyaF1M%2FhsVSktA%3D%3D
    • Ayala FJ 1968 Biology as an autonomous science. Am. Sci. 56 207-221
    • (1968) Am. Sci. , vol.56 , pp. 207-221
    • Ayala, F.J.1
  • 5
    • 84874821233 scopus 로고    scopus 로고
    • Paradoxes in carcinogenesis should spur new avenues of research: An historical perspective
    • 10.1089/dst.2012.0011
    • Baker SG 2012 Paradoxes in carcinogenesis should spur new avenues of research: An historical perspective. Disruptive Sci. Technol. 1 100-107
    • (2012) Disruptive Sci. Technol. , vol.1 , pp. 100-107
    • Baker, S.G.1
  • 6
    • 84883168743 scopus 로고    scopus 로고
    • Paradox-driven cancer research
    • 10.1089/dst.2012.0029
    • Baker SG 2013 Paradox-driven cancer research. Disruptive Sci. Technol. 1 143-148
    • (2013) Disruptive Sci. Technol. , vol.1 , pp. 143-148
    • Baker, S.G.1
  • 8
    • 84859766256 scopus 로고    scopus 로고
    • Hierarchies and causal relationships in interpretative models of the neoplastic process
    • Bertolaso M 2011 Hierarchies and causal relationships in interpretative models of the neoplastic process. Hist. Phil. Life Sci. 33 515-535
    • (2011) Hist. Phil. Life Sci. , vol.33 , pp. 515-535
    • Bertolaso, M.1
  • 9
    • 0026010995 scopus 로고
    • Molecular themes in oncogenesis
    • 1988146 10.1016/0092-8674(91)90636-D 1:CAS:528:DyaK3MXpvFWksQ%3D%3D
    • Bishop JM 1991 Molecular themes in oncogenesis. Cell 64 235-248
    • (1991) Cell , vol.64 , pp. 235-248
    • Bishop, J.M.1
  • 10
    • 48349084126 scopus 로고    scopus 로고
    • Beyond the oncogene paradigm: Understanding complexity in cancerogenesis
    • 18288572 10.1007/s10441-008-9047-8 1:STN:280:DC%2BD1cvntVGltw%3D%3D
    • Bizzarri M, Cucina A, Conti F and D'Anselmi F 2008 Beyond the oncogene paradigm: understanding complexity in cancerogenesis. Acta Biotheor. 56 173-196
    • (2008) Acta Biotheor. , vol.56 , pp. 173-196
    • Bizzarri, M.1    Cucina, A.2    Conti, F.3    D'Anselmi, F.4
  • 11
    • 79951509549 scopus 로고    scopus 로고
    • The normal mammary microenvironment suppresses the tumorigenic phenotype of mouse mammary tumor virus-neu-transformed mammary tumor cells
    • 20890308 10.1038/onc.2010.439 1:CAS:528:DC%2BC3cXht1elu77P
    • Booth BW, Boulanger CA, Anderson LH and Smith GH 2011 The normal mammary microenvironment suppresses the tumorigenic phenotype of mouse mammary tumor virus-neu-transformed mammary tumor cells. Oncogene 30 679-689
    • (2011) Oncogene , vol.30 , pp. 679-689
    • Booth, B.W.1    Boulanger, C.A.2    Anderson, L.H.3    Smith, G.H.4
  • 12
    • 84863908036 scopus 로고    scopus 로고
    • Theorists feast on Higgs data
    • 22810668 10.1038/487281a 1:CAS:528:DC%2BC38XhtVKnurvO
    • Brumfiel G 2012 Theorists feast on Higgs data. Nature 487 281
    • (2012) Nature , vol.487 , pp. 281
    • Brumfiel, G.1
  • 13
    • 77955382734 scopus 로고    scopus 로고
    • Reprogramming human cancer cells in the mouse mammary gland
    • 20647316 10.1158/0008-5472.CAN-10-0591 1:CAS:528:DC%2BC3cXpsVCnuro%3D
    • Bussard KM, Boulanger CA, Booth BW, Bruno RD and Smith GH 2010 Reprogramming human cancer cells in the mouse mammary gland. Cancer Res. 70 6336-6343
    • (2010) Cancer Res. , vol.70 , pp. 6336-6343
    • Bussard, K.M.1    Boulanger, C.A.2    Booth, B.W.3    Bruno, R.D.4    Smith, G.H.5
  • 14
    • 37549036339 scopus 로고    scopus 로고
    • 'One medicine -One pathology': Are veterinary and human pathology prepared?
    • 18040269 10.1038/labinvest.3700695
    • Cardiff RD, Ward JM and Barthold SW 2008 'One medicine - one pathology': are veterinary and human pathology prepared? Lab Invest. 88 18-26
    • (2008) Lab Invest. , vol.88 , pp. 18-26
    • Cardiff, R.D.1    Ward, J.M.2    Barthold, S.W.3
  • 16
    • 84883191500 scopus 로고
    • The stimulation of epidermal keratinization by a protein isolated from the submaxillary gland of the mouse
    • Cohen S and Elliot GA 1962 The stimulation of epidermal keratinization by a protein isolated from the submaxillary gland of the mouse. J. Invest. Dermat. 49 1-5
    • (1962) J. Invest. Dermat. , vol.49 , pp. 1-5
    • Cohen, S.1    Elliot, G.A.2
  • 18
    • 37049181624 scopus 로고
    • Tritiated thymidine incorporation does not measure DNA synthesis in ribavirin-treated human cells
    • 7209549 10.1126/science.7209549 1:CAS:528:DyaL3MXktVShu7c%3D
    • Drach JC, Thomas MA, Barnett JW, Smith SH and Shipman C Jr 1981 Tritiated thymidine incorporation does not measure DNA synthesis in ribavirin-treated human cells. Science 212 549-551
    • (1981) Science , vol.212 , pp. 549-551
    • Drach, J.C.1    Thomas, M.A.2    Barnett, J.W.3    Smith, S.H.4    Shipman, Jr.C.5
  • 20
    • 2542430341 scopus 로고    scopus 로고
    • The three Es of cancer immunoediting
    • 15032581 10.1146/annurev.immunol.22.012703.104803 1:CAS:528: DC%2BD2cXktlOgs7k%3D
    • Dunn GP, Old LJ and Schreiber RD 2004 The three Es of cancer immunoediting. Annu. Rev. Immunol. 22 329-360
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 329-360
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 22
    • 79953244361 scopus 로고    scopus 로고
    • Antiangiogenic therapy: Impact on invasion, disease progression, and metastasis
    • 21364524 10.1038/nrclinonc.2011.21 1:CAS:528:DC%2BC3MXjvFKlsLg%3D
    • Ebos JM and Kerbel RS 2011 Antiangiogenic therapy: impact on invasion, disease progression, and metastasis. Nat. Rev. Clin. Oncol. 8 210-221
    • (2011) Nat. Rev. Clin. Oncol. , vol.8 , pp. 210-221
    • Ebos, J.M.1    Kerbel, R.S.2
  • 24
  • 25
    • 80051641315 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumors: Is 'evading apoptosis' a hallmark of cancer?
    • 21473880 10.1016/j.pbiomolbio.2011.03.007
    • Enderling H and Hahnfeldt P 2011 Cancer stem cells in solid tumors: Is 'evading apoptosis' a hallmark of cancer? Prog. Biophys. Mol. Biol. 106 391-399
    • (2011) Prog. Biophys. Mol. Biol. , vol.106 , pp. 391-399
    • Enderling, H.1    Hahnfeldt, P.2
  • 26
    • 0030272703 scopus 로고    scopus 로고
    • Is cancer dangerous to the immune system?
    • 8956455 10.1006/smim.1996.0035 1:CAS:528:DyaK2sXivVektA%3D%3D
    • Fuchs EJ and Matzinger P 1996 Is cancer dangerous to the immune system? Semin. Immunol. 8 271-280
    • (1996) Semin. Immunol. , vol.8 , pp. 271-280
    • Fuchs, E.J.1    Matzinger, P.2
  • 27
    • 84875758730 scopus 로고    scopus 로고
    • Lessons from the cancer genome
    • 23540688 10.1016/j.cell.2013.03.002 1:CAS:528:DC%2BC3sXltVensb0%3D
    • Garraway LV and Lander EC 2013 Lessons from the cancer genome. Cell 153 17-37
    • (2013) Cell , vol.153 , pp. 17-37
    • Garraway, L.V.1    Lander, E.C.2
  • 29
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • 10647931 10.1016/S0092-8674(00)81683-9 1:CAS:528:DC%2BD3cXks1CktA%3D%3D
    • Hanahan D and Weinberg RA 2000 The hallmarks of cancer. Cell 100 57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 30
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • 21376230 10.1016/j.cell.2011.02.013 1:CAS:528:DC%2BC3MXjsFeqtrk%3D
    • Hanahan D and Weinberg RA 2011 Hallmarks of cancer: the next generation. Cell 144 646-674
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 31
    • 1642512402 scopus 로고    scopus 로고
    • Tumor suppression: Putting on the breaks
    • 14724616 10.1038/427201a 1:CAS:528:DC%2BD2cXjtFGrtQ%3D%3D
    • Harris H 2004 Tumor suppression: putting on the breaks. Nature 427 201
    • (2004) Nature , vol.427 , pp. 201
    • Harris, H.1
  • 33
    • 2042435768 scopus 로고
    • Totipotency and normal differentiation of single teratocarcinoma cell cloned by injection into blastocysts
    • 1061157 10.1073/pnas.73.2.549 1:STN:280:DyaE287gt1ygsg%3D%3D
    • Illmensee K and Mintz B 1976 Totipotency and normal differentiation of single teratocarcinoma cell cloned by injection into blastocysts. Proc. Nat. Acad. Sci. USA 73 549-553
    • (1976) Proc. Nat. Acad. Sci. USA , vol.73 , pp. 549-553
    • Illmensee, K.1    Mintz, B.2
  • 35
    • 84906888411 scopus 로고    scopus 로고
    • Interagency Breast Cancer & Environmental Research Coordinating Committee
    • Interagency Breast Cancer & Environmental Research Coordinating Committee. 2013 Breast cancer and the environment: Prioritizing prevention (http://www.niehs.nih.gov/about/assets/docs/ibcercc-full.pdf)
    • 2013 Breast Cancer and the Environment: Prioritizing Prevention
  • 36
    • 0037007430 scopus 로고    scopus 로고
    • Ras inducible immortalized fibroblasts: Focus formation without cell cycle deregulation
    • 12082537 10.1038/sj.onc.1205423 1:CAS:528:DC%2BD38XjvFeju70%3D
    • Jacobsen K, Groth A and Willumsen B 2002 Ras inducible immortalized fibroblasts: focus formation without cell cycle deregulation. Oncogene 21 3058-3067
    • (2002) Oncogene , vol.21 , pp. 3058-3067
    • Jacobsen, K.1    Groth, A.2    Willumsen, B.3
  • 37
    • 84864007902 scopus 로고    scopus 로고
    • Profile: Bert Vogelstein. Cancer genetics with an edge
    • 22822123 10.1126/science.337.6092.282
    • Kaiser J 2012 Profile: Bert Vogelstein. Cancer genetics with an edge. Science 337 282-284
    • (2012) Science , vol.337 , pp. 282-284
    • Kaiser, J.1
  • 38
    • 34547640147 scopus 로고    scopus 로고
    • The evolving concept of tumor microenvironments
    • 17621638 10.1002/bies.20606 1:CAS:528:DC%2BD2sXhtVSksb%2FL
    • Laconi E 2007 The evolving concept of tumor microenvironments. BioEssays 29 738-744
    • (2007) BioEssays , vol.29 , pp. 738-744
    • Laconi, E.1
  • 39
    • 77950020483 scopus 로고    scopus 로고
    • What are the hallmarks of cancer?
    • 20355252 10.1038/nrc2827 1:CAS:528:DC%2BC3cXjtVWrsLs%3D
    • Lazebnik Y 2010 What are the hallmarks of cancer? Nat. Rev. Cancer 10 232-233
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 232-233
    • Lazebnik, Y.1
  • 40
    • 70350603183 scopus 로고
    • The nerve growth factor: Thirty-five years later
    • Levi-Montalcini R 1986 The nerve growth factor: thirty-five years later. The Nobel Lectures 279-299
    • (1986) The Nobel Lectures , pp. 279-299
    • Levi-Montalcini, R.1
  • 41
    • 80053005260 scopus 로고    scopus 로고
    • Introduction: The changing directions of p53 research
    • 21785490 10.1177/1947601911413463
    • Levine AJ 2011 Introduction: The changing directions of p53 research. Genes Cancer 2 382-384
    • (2011) Genes Cancer , vol.2 , pp. 382-384
    • Levine, A.J.1
  • 43
    • 84864543987 scopus 로고    scopus 로고
    • Is information a proper observable for biological organization?
    • 22796169 10.1016/j.pbiomolbio.2012.06.004 1:STN:280: DC%2BC38fgtVSntQ%3D%3D
    • Longo G, Miquel P-A, Sonnenschein C and Soto AM 2012 Is information a proper observable for biological organization? Prog. Biophys. Mol. Biol. 109 108-14
    • (2012) Prog. Biophys. Mol. Biol. , vol.109 , pp. 108-114
    • Longo, G.1    Miquel, P.-A.2    Sonnenschein, C.3    Soto, A.M.4
  • 44
    • 0037019164 scopus 로고    scopus 로고
    • Immortalization and transformation of primary human airway epithelial cells by gene transfer
    • 12085236 10.1038/sj.onc.1205550 1:CAS:528:DC%2BD38Xksl2mt7g%3D
    • Lundberg AS, Randell SH, Stewart SA, Elenbaas B, Hartwell KA, Brooks MW, Fleming MD, et al. 2002 Immortalization and transformation of primary human airway epithelial cells by gene transfer. Oncogene 21 4577-4586
    • (2002) Oncogene , vol.21 , pp. 4577-4586
    • Lundberg, A.S.1    Randell, S.H.2    Stewart, S.A.3    Elenbaas, B.4    Hartwell, K.A.5    Brooks, M.W.6    Fleming, M.D.7
  • 45
    • 84883170219 scopus 로고
    • Lecture 1
    • (Cambridge: MIT Press)
    • Luria SE 1975 Lecture 1; in 36 Lectures in biology (Cambridge: MIT Press) pp 3-14
    • (1975) 36 Lectures in Biology , pp. 3-14
    • Luria, S.E.1
  • 46
    • 27544510187 scopus 로고    scopus 로고
    • Stromal regulation of neoplastic development: Age-dependent normalization of neoplastic mammary cells by mammary stroma
    • 16251424 10.1016/S0002-9440(10)61227-8
    • Maffini MV, Calabro JM, Soto AM and Sonnenschein C 2005 Stromal regulation of neoplastic development: Age-dependent normalization of neoplastic mammary cells by mammary stroma. Am. J. Pathol. 167 1405-1410
    • (2005) Am. J. Pathol. , vol.167 , pp. 1405-1410
    • Maffini, M.V.1    Calabro, J.M.2    Soto, A.M.3    Sonnenschein, C.4
  • 47
    • 2342441403 scopus 로고    scopus 로고
    • The stroma as a crucial target in rat mammary gland carcinogenesis
    • 14996910 10.1242/jcs.01000 1:CAS:528:DC%2BD2cXjs1ygu70%3D
    • Maffini MV, Soto AM, Calabro JM, Ucci AA and Sonnenschein C 2004 The stroma as a crucial target in rat mammary gland carcinogenesis. J. Cell Sci. 117 1495-1502
    • (2004) J. Cell Sci. , vol.117 , pp. 1495-1502
    • Maffini, M.V.1    Soto, A.M.2    Calabro, J.M.3    Ucci, A.A.4    Sonnenschein, C.5
  • 48
    • 33645213254 scopus 로고    scopus 로고
    • Metaphysical presuppositions and scientific practices: Reductionism and organicism in cancer research
    • 10.1080/02698590500051076
    • Marcum JA 2005 Metaphysical presuppositions and scientific practices: Reductionism and organicism in cancer research. Int. Stud. Philos. Sci. 19 31-45
    • (2005) Int. Stud. Philos. Sci. , vol.19 , pp. 31-45
    • Marcum, J.A.1
  • 49
    • 22844451300 scopus 로고    scopus 로고
    • The human cancer genome project - One more mistep in the war on cancer
    • 10.1038/nbt0505-535
    • Miklos GLG 2005 The human cancer genome project - one more mistep in the war on cancer. Nat. Biotechnol. 23 535-537
    • (2005) Nat. Biotechnol. , vol.23 , pp. 535-537
    • Miklos, G.L.G.1
  • 50
    • 0345366593 scopus 로고
    • Normal genetically mosaic mice produced from malignant teratocarcinoma cells
    • 1059147 10.1073/pnas.72.9.3585 1:STN:280:DyaE28%2FltlWltQ%3D%3D
    • Mintz B and Ilmensee K 1975 Normal genetically mosaic mice produced from malignant teratocarcinoma cells. Proc. Nat. Acad. Sci. USA 72 3585-3589
    • (1975) Proc. Nat. Acad. Sci. USA , vol.72 , pp. 3585-3589
    • Mintz, B.1    Ilmensee, K.2
  • 53
    • 84859000573 scopus 로고    scopus 로고
    • Evolution of the cancer genome
    • 22342180 10.1016/j.tig.2012.01.003 1:CAS:528:DC%2BC38XivFyhtbs%3D
    • Podlaha O, Riester M, De S and Michor F 2012 Evolution of the cancer genome. Trends Genet. 28 155-163
    • (2012) Trends Genet. , vol.28 , pp. 155-163
    • Podlaha, O.1    Riester, M.2    De, S.3    Michor, F.4
  • 54
    • 3142577806 scopus 로고
    • Johns Hopkins University Press Baltimore
    • Rather LJ 1978 The genesis of cancer (Baltimore: Johns Hopkins University Press)
    • (1978) The Genesis of Cancer
    • Rather, L.J.1
  • 55
    • 79951550303 scopus 로고    scopus 로고
    • Fields and field cancerization: The preneoplastic origins of cancer: Asymptomatic hyperplastic fields are precursors of neoplasia, and their progression to tumors can be tracked by saturation density in culture
    • 21254148 10.1002/bies.201000067
    • Rubin H 2011a Fields and field cancerization: the preneoplastic origins of cancer: asymptomatic hyperplastic fields are precursors of neoplasia, and their progression to tumors can be tracked by saturation density in culture. BioEssays 33 224-231
    • (2011) BioEssays , vol.33 , pp. 224-231
    • Rubin, H.1
  • 56
    • 80052279883 scopus 로고    scopus 로고
    • The early history of tumor virology: Rous, RIF, and RAV
    • 21813762 10.1073/pnas.1108655108 1:CAS:528:DC%2BC3MXhtFCltbvE
    • Rubin H 2011b The early history of tumor virology: Rous, RIF, and RAV. Proc. Nat. Acad. Sci. USA 108 14389-14396
    • (2011) Proc. Nat. Acad. Sci. USA , vol.108 , pp. 14389-14396
    • Rubin, H.1
  • 57
    • 0025726339 scopus 로고
    • Transformation of a mammary epithelial cell line by the v-raf and v-mos oncogenes
    • 1826898 10.1002/ijc.2910480123 1:CAS:528:DyaK3MXlslKgtrw%3D
    • Scully JL and Edwards PA 1991 Transformation of a mammary epithelial cell line by the v-raf and v-mos oncogenes. Int. J. Cancer 48 128-135
    • (1991) Int. J. Cancer , vol.48 , pp. 128-135
    • Scully, J.L.1    Edwards, P.A.2
  • 58
    • 84875486180 scopus 로고    scopus 로고
    • Mdm2 and tumorigenesis: Evolving theories and unsolved mysteries
    • 23150752 10.1177/1947601912457368
    • Senturk E and Manfredi JJ 2012 Mdm2 and tumorigenesis: evolving theories and unsolved mysteries. Genes Cancer 3 192-198
    • (2012) Genes Cancer , vol.3 , pp. 192-198
    • Senturk, E.1    Manfredi, J.J.2
  • 59
    • 0038614781 scopus 로고    scopus 로고
    • Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation
    • 12805214 10.1093/emboj/cdg291 1:CAS:528:DC%2BD3sXks1Wru7s%3D
    • Sharov AA, Weiner L, Sharova TY, Siebenhaar F, Atoyan R, Reginato AM, McNamara CA, Funa K, et al. 2003 Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation. EMBO J. 22 2992-3003
    • (2003) EMBO J. , vol.22 , pp. 2992-3003
    • Sharov, A.A.1    Weiner, L.2    Sharova, T.Y.3    Siebenhaar, F.4    Atoyan, R.5    Reginato, A.M.6    McNamara, C.A.7    Funa, K.8
  • 60
    • 0018843910 scopus 로고
    • But are estrogens per se growth-promoting hormones?
    • 6986492 1:CAS:528:DyaL3cXhs1WjsLs%3D
    • Sonnenschein C and Soto AM 1980 But. are estrogens per se growth-promoting hormones?. J. Nat. Cancer Inst. 64 211-215
    • (1980) J. Nat. Cancer Inst , vol.64 , pp. 211-215
    • Sonnenschein, C.1    Soto, A.M.2
  • 62
    • 0034524531 scopus 로고    scopus 로고
    • The somatic mutation theory of carcinogenesis: Why it should be dropped and replaced
    • 10.1002/1098-2744(200012)29:4<205: AID-MC1002>3.0.CO;2-W
    • Sonnenschein C and Soto AM 2000 The somatic mutation theory of carcinogenesis: Why it should be dropped and replaced. Mol. Carcinog. 29 1-7
    • (2000) Mol. Carcinog. , vol.29 , pp. 1-7
    • Sonnenschein, C.1    Soto, A.M.2
  • 63
    • 48349090284 scopus 로고    scopus 로고
    • Theories of carcinogenesis: An emerging perspective
    • 18472276 10.1016/j.semcancer.2008.03.012 1:CAS:528:DC%2BD1cXpsVGmsLk%3D
    • Sonnenschein C and Soto AM 2008 Theories of carcinogenesis: an emerging perspective. Semin. Cancer Biol. 18 372-377
    • (2008) Semin. Cancer Biol. , vol.18 , pp. 372-377
    • Sonnenschein, C.1    Soto, A.M.2
  • 64
    • 79959900938 scopus 로고    scopus 로고
    • The death of the cancer cell
    • 21507929 10.1158/0008-5472.CAN-11-0639 1:CAS:528:DC%2BC3MXotlersL8%3D
    • Sonnenschein C and Soto AM 2011 The death of the cancer cell. Cancer Res. 71 4334-4337
    • (2011) Cancer Res. , vol.71 , pp. 4334-4337
    • Sonnenschein, C.1    Soto, A.M.2
  • 65
    • 0023285716 scopus 로고
    • Cell proliferation of estrogen-sensitive cells: The case for negative control
    • 3549277 10.1210/edrv-8-1-44 1:CAS:528:DyaL2sXktlehsLw%3D
    • Soto AM and Sonnenschein C 1987 Cell proliferation of estrogen-sensitive cells: the case for negative control. Endocr. Rev. 8 44-52
    • (1987) Endocr. Rev. , vol.8 , pp. 44-52
    • Soto, A.M.1    Sonnenschein, C.2
  • 66
    • 7044264244 scopus 로고    scopus 로고
    • The somatic mutation theory of cancer: Growing problems with the paradigm?
    • 15382143 10.1002/bies.20087 1:CAS:528:DC%2BD2cXpt1GltLs%3D
    • Soto AM and Sonnenschein C 2004 The somatic mutation theory of cancer: growing problems with the paradigm? BioEssays 26 1097-1107
    • (2004) BioEssays , vol.26 , pp. 1097-1107
    • Soto, A.M.1    Sonnenschein, C.2
  • 67
    • 79954623572 scopus 로고    scopus 로고
    • The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory
    • 21503935 10.1002/bies.201100025
    • Soto AM and Sonnenschein C 2011 The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory. BioEssays 33 332-340
    • (2011) BioEssays , vol.33 , pp. 332-340
    • Soto, A.M.1    Sonnenschein, C.2
  • 68
    • 84858726938 scopus 로고    scopus 로고
    • Is systems biology a promising approach to resolve controversies in cancer research?
    • 22449120 10.1186/1475-2867-12-12
    • Soto AM and Sonnenschein C 2012 Is systems biology a promising approach to resolve controversies in cancer research? Cancer Cell Int. 12 12
    • (2012) Cancer Cell Int. , vol.12 , pp. 12
    • Soto, A.M.1    Sonnenschein, C.2
  • 69
    • 57049112129 scopus 로고    scopus 로고
    • On physicalism and Downward Causation in Developmental and Cancer Biology
    • 18542843 10.1007/s10441-008-9052-y 1:STN:280:DC%2BD1cjmtlSjsw%3D%3D
    • Soto AM, Sonnenschein C and Miquel P-A 2008 On physicalism and Downward Causation in Developmental and Cancer Biology. Acta Biotheoretica 56 257-274
    • (2008) Acta Biotheoretica , vol.56 , pp. 257-274
    • Soto, A.M.1    Sonnenschein, C.2    Miquel, P.-A.3
  • 70
    • 0015977440 scopus 로고
    • Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice
    • 4588620 10.1126/science.183.4124.534 1:CAS:528:DyaE2cXktVahtbw%3D
    • Stutman O 1974 Tumor development after 3-methylcholanthrene in immunologically deficient athymic-nude mice. Science 183 534-536
    • (1974) Science , vol.183 , pp. 534-536
    • Stutman, O.1
  • 71
    • 84883170882 scopus 로고    scopus 로고
    • The myth of the machine-organism from genetic mechanisms to living beings
    • S. Krimsky J. Gruber (eds) Harvard University Press Cambridge, MA
    • Tallbot SL 2013 The myth of the machine-organism from genetic mechanisms to living beings; in Genetic explanations, sense and nonsense (eds) S Krimsky and J Gruber (Cambridge, MA: Harvard University Press) pp 51-68
    • (2013) Genetic Explanations, Sense and Nonsense , pp. 51-68
    • Tallbot, S.L.1
  • 72
    • 79952068436 scopus 로고    scopus 로고
    • Cell and tissue interactions in carcinogenesis and metastasis and their clinical significance
    • 21147229 10.1016/j.semcancer.2010.12.006 1:CAS:528:DC%2BC3MXjs1Crtbg%3D
    • Tarin D 2011 Cell and tissue interactions in carcinogenesis and metastasis and their clinical significance. Semin. Cancer Biol. 21 72-82
    • (2011) Semin. Cancer Biol. , vol.21 , pp. 72-82
    • Tarin, D.1
  • 73
    • 22244473343 scopus 로고    scopus 로고
    • The fallacy of epithelial mesenchymal transition in neoplasia
    • 16024596 10.1158/0008-5472.CAN-05-0699 1:CAS:528:DC%2BD2MXmt1ehtrs%3D
    • Tarin D, Thompson EW and Newgreen DF 2005 The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Res. 65 5996-6000
    • (2005) Cancer Res. , vol.65 , pp. 5996-6000
    • Tarin, D.1    Thompson, E.W.2    Newgreen, D.F.3
  • 74
    • 84875145218 scopus 로고    scopus 로고
    • Addressing the growing international challenge of cancer: A multinational perspective
    • 10.1126/scitranslmed.3005899 23467558
    • Varmus H and Kumar HS 2013 Addressing the growing international challenge of cancer: a multinational perspective. Sci. Transl. Med. doi: 10.1126/scitranslmed.3005899
    • (2013) Sci. Transl. Med.
    • Varmus, H.1    Kumar, H.S.2
  • 75
    • 78751676408 scopus 로고    scopus 로고
    • Cells of origin in cancer
    • 21248838 10.1038/nature09781 1:CAS:528:DC%2BC3MXnvVKjtQ%3D%3D
    • Visvader JE 2011 Cells of origin in cancer. Nature 469 314-322
    • (2011) Nature , vol.469 , pp. 314-322
    • Visvader, J.E.1
  • 79
    • 0022746384 scopus 로고
    • Metabolic breakdown of [3H] thymidine and the inability to measure human lymphocyte proliferation by incorporation of radioactivity
    • 3460068 10.1073/pnas.83.13.4749
    • Wolff S and Bodycote J 1986 Metabolic breakdown of [3H] thymidine and the inability to measure human lymphocyte proliferation by incorporation of radioactivity. Proc. Nat. Acad. Sci. USA 83 4749-4753
    • (1986) Proc. Nat. Acad. Sci. USA , vol.83 , pp. 4749-4753
    • Wolff, S.1    Bodycote, J.2
  • 81
    • 0038644122 scopus 로고    scopus 로고
    • Regulation of quiescence in lymphocytes
    • 12860529 10.1016/S1471-4906(03)00141-8 1:CAS:528:DC%2BD3sXlsVWltbc%3D
    • Yusuf I and Fruman DA 2003 Regulation of quiescence in lymphocytes. Trends in Immunology 24 380-386
    • (2003) Trends in Immunology , vol.24 , pp. 380-386
    • Yusuf, I.1    Fruman, D.A.2


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