-
1
-
-
84887437596
-
Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment
-
Sui X, Chen R, Wang Z et al. Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment. Cell Death Dis 2013; 4: e838.
-
(2013)
Cell Death Dis
, vol.4
, pp. e838
-
-
Sui, X.1
Chen, R.2
Wang, Z.3
-
2
-
-
84879780600
-
Autophagy: shaping the tumor microenvironment and therapeutic response
-
Maes H, Rubio N, Garg AD, Agostinis P. Autophagy: shaping the tumor microenvironment and therapeutic response. Trends Mol Med 2013; 19: e51076.
-
(2013)
Trends Mol Med
, vol.19
, pp. e51076
-
-
Maes, H.1
Rubio, N.2
Garg, A.D.3
Agostinis, P.4
-
3
-
-
84870591168
-
Autophagy protects against oxaliplatin-induced cell death via ER stress and ROS in Caco-2 cells
-
Shi Y, Tang B, Yu PW et al. Autophagy protects against oxaliplatin-induced cell death via ER stress and ROS in Caco-2 cells. PLoS One 2012; 7: e51076.
-
(2012)
PLoS One
, vol.7
, pp. e51076
-
-
Shi, Y.1
Tang, B.2
Yu, P.W.3
-
4
-
-
77951220669
-
Role of autophagy in suppression of inflammation and cancer
-
White E, Karp C, Strohecker AM, Guo Y, Mathew R. Role of autophagy in suppression of inflammation and cancer. Curr Opin Cell Biol 2010; 22: 212-7.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 212-217
-
-
White, E.1
Karp, C.2
Strohecker, A.M.3
Guo, Y.4
Mathew, R.5
-
5
-
-
78751556979
-
Autophagy as a therapeutic target in cancer
-
Chen N, Karantza V. Autophagy as a therapeutic target in cancer. Cancer Biol Ther 2011; 11: 157-68.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 157-168
-
-
Chen, N.1
Karantza, V.2
-
6
-
-
80053575783
-
The multifaceted roles of autophagy in tumors-implications for breast cancer
-
Debnath J. The multifaceted roles of autophagy in tumors-implications for breast cancer. J Mammary Gland Biol Neoplasia 2011; 16: 173-87.
-
(2011)
J Mammary Gland Biol Neoplasia
, vol.16
, pp. 173-187
-
-
Debnath, J.1
-
7
-
-
79951847989
-
Principles and current strategies for targeting autophagy for cancer treatment
-
Amaravadi RK, Lippincott-Schwartz J, Yin X-M et al. Principles and current strategies for targeting autophagy for cancer treatment. Clin Cancer Res 2011; 17: 654-66.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 654-666
-
-
Amaravadi, R.K.1
Lippincott-Schwartz, J.2
Yin, X.-M.3
-
9
-
-
84878259408
-
Different administration strategies with paclitaxel induce distinct phenotypes of multidrug resistance in breast cancer cells
-
Jiang D, Sui M, Zhong W, Huang Y, Fan W. Different administration strategies with paclitaxel induce distinct phenotypes of multidrug resistance in breast cancer cells. Cancer Lett 2013; 335: 404-11.
-
(2013)
Cancer Lett
, vol.335
, pp. 404-411
-
-
Jiang, D.1
Sui, M.2
Zhong, W.3
Huang, Y.4
Fan, W.5
-
10
-
-
84887140160
-
Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin
-
Kim TH, Shin YJ, Won AJ et al. Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin. Biochim Biophys Acta 2014; 1840: 615-25.
-
(2014)
Biochim Biophys Acta
, vol.1840
, pp. 615-625
-
-
Kim, T.H.1
Shin, Y.J.2
Won, A.J.3
-
11
-
-
84887216989
-
Enhanced cytotoxicity of optimized liposomal genistein via specific induction of apoptosis in breast, ovarian and prostate carcinomas
-
Vu P, Walters J, Brownlow B, Elbayoumi T. Enhanced cytotoxicity of optimized liposomal genistein via specific induction of apoptosis in breast, ovarian and prostate carcinomas. J Drug Target 2013; 21: 1001-11.
-
(2013)
J Drug Target
, vol.21
, pp. 1001-1011
-
-
Vu, P.1
Walters, J.2
Brownlow, B.3
Elbayoumi, T.4
-
12
-
-
84862796733
-
Ampelopsin sodium exhibits antitumor effects against bladder carcinoma in orthotopic xenograft models
-
Zhang B, Dong S, Cen X et al. Ampelopsin sodium exhibits antitumor effects against bladder carcinoma in orthotopic xenograft models. Anticancer Drugs 2012; 23: 590-6.
-
(2012)
Anticancer Drugs
, vol.23
, pp. 590-596
-
-
Zhang, B.1
Dong, S.2
Cen, X.3
-
13
-
-
84856091690
-
Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-kappa B signaling pathways
-
Qi S, Xin Y, Guo Y et al. Ampelopsin reduces endotoxic inflammation via repressing ROS-mediated activation of PI3K/Akt/NF-kappa B signaling pathways. Int Immunopharmacol 2012; 12: 278-87.
-
(2012)
Int Immunopharmacol
, vol.12
, pp. 278-287
-
-
Qi, S.1
Xin, Y.2
Guo, Y.3
-
14
-
-
84861897760
-
Flavonoid Ampelopsin inhibits the growth and metastasis of prostate cancer in vitro and in mice
-
Ni F, Gong Y, Li L, Abdolmaleky HM, Zhou J-R. Flavonoid Ampelopsin inhibits the growth and metastasis of prostate cancer in vitro and in mice. PLoS One 2012; 7: e38802.
-
(2012)
PLoS One
, vol.7
, pp. e38802
-
-
Ni, F.1
Gong, Y.2
Li, L.3
Abdolmaleky, H.M.4
Zhou, J.-R.5
-
15
-
-
84895829916
-
Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway
-
Zhou Y, Shu F, Liang X et al. Ampelopsin induces cell growth inhibition and apoptosis in breast cancer cells through ROS generation and endoplasmic reticulum stress pathway. PLoS One 2014; 9: e89021.
-
(2014)
PLoS One
, vol.9
, pp. e89021
-
-
Zhou, Y.1
Shu, F.2
Liang, X.3
-
16
-
-
84887078420
-
Metabolic complications with the use of mTOR inhibitors for cancer therapy
-
Sivendran S, Agarwal N, Gartrell B et al. Metabolic complications with the use of mTOR inhibitors for cancer therapy. Cancer Treat Rev 2014; 40: 190-6.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 190-196
-
-
Sivendran, S.1
Agarwal, N.2
Gartrell, B.3
-
17
-
-
84888297088
-
Noninfectious pneumonitis with the use of mTOR inhibitors in breast cancer
-
Peddi PF, Shatsky RA, Hurvitz SA. Noninfectious pneumonitis with the use of mTOR inhibitors in breast cancer. Cancer Treat Rev 2014; 40: 320-6.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 320-326
-
-
Peddi, P.F.1
Shatsky, R.A.2
Hurvitz, S.A.3
-
18
-
-
80054087824
-
Mitochondrial ROS generation for regulation of autophagic pathways in cancer
-
Li Z-Y, Yang Y, Ming M, Liu B. Mitochondrial ROS generation for regulation of autophagic pathways in cancer. Biochem Biophys Res Commun 2011; 414: 5-8.
-
(2011)
Biochem Biophys Res Commun
, vol.414
, pp. 5-8
-
-
Li, Z.-Y.1
Yang, Y.2
Ming, M.3
Liu, B.4
-
19
-
-
84879289875
-
Anthricin isolated from Anthriscus sylvestris (L.) Hoffm. inhibits the growth of breast cancer cells by inhibiting Akt/mTOR signaling, and its apoptotic effects are enhanced by autophagy inhibition
-
Jung CH, Kim H, Ahn J et al. Anthricin isolated from Anthriscus sylvestris (L.) Hoffm. inhibits the growth of breast cancer cells by inhibiting Akt/mTOR signaling, and its apoptotic effects are enhanced by autophagy inhibition. Evid Based Complement Alternat Med 2013; 2013: e385219.
-
(2013)
Evid Based Complement Alternat Med
, vol.2013
, pp. e385219
-
-
Jung, C.H.1
Kim, H.2
Ahn, J.3
-
20
-
-
84872810600
-
Diarylquinoline compounds induce autophagy-associated cell death by inhibiting the Akt pathway and increasing reactive oxygen species in human nasopharyngeal carcinoma cells
-
Cai Y, Wang Z, Sun T et al. Diarylquinoline compounds induce autophagy-associated cell death by inhibiting the Akt pathway and increasing reactive oxygen species in human nasopharyngeal carcinoma cells. Oncol Rep 2013; 29: 983-92.
-
(2013)
Oncol Rep
, vol.29
, pp. 983-992
-
-
Cai, Y.1
Wang, Z.2
Sun, T.3
-
21
-
-
80052064898
-
20(S)-Protopanaxadiol, a metabolite of ginsenosides, induced cell apoptosis through endoplasmic reticulum stress in human hepatocarcinoma HepG2 cells
-
Zhu G-Y, Li Y-W, Tse AK-W et al. 20(S)-Protopanaxadiol, a metabolite of ginsenosides, induced cell apoptosis through endoplasmic reticulum stress in human hepatocarcinoma HepG2 cells. Eur J Pharmacol 2011; 668: 88-98.
-
(2011)
Eur J Pharmacol
, vol.668
, pp. 88-98
-
-
Zhu, G.-Y.1
Li, Y.-W.2
Tse, A.-W.3
-
23
-
-
77955947900
-
Linking ER stress to autophagy: potential implications for cancer therapy
-
Verfaillie T, Salazar M, Velasco G, Agostinis P. Linking ER stress to autophagy: potential implications for cancer therapy. Int J Cell Biol 2010; 2010: 930509.
-
(2010)
Int J Cell Biol
, vol.2010
, pp. 930509
-
-
Verfaillie, T.1
Salazar, M.2
Velasco, G.3
Agostinis, P.4
-
24
-
-
84911214923
-
Endoplasmic reticulum stress can upregulate activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP) expression via a PKR-like ER kinase (PERK) independent pathway in pancreatic beta cells
-
Zhao XC, Omikorede O, Smith D, Herbert TP. Endoplasmic reticulum stress can upregulate activating transcription factor 4 (ATF4) and C/EBP homologous protein (CHOP) expression via a PKR-like ER kinase (PERK) independent pathway in pancreatic beta cells. Diabet Med 2013; 30: 33-3.
-
(2013)
Diabet Med
, vol.30
, pp. 33-33
-
-
Zhao, X.C.1
Omikorede, O.2
Smith, D.3
Herbert, T.P.4
-
25
-
-
84884992945
-
Zoledronic acid-induced cytotoxicity through endoplasmic reticulum stress triggered REDD1-mTOR pathway in breast cancer cells
-
Lan Y-C, Chang C-L, Sung M-T et al. Zoledronic acid-induced cytotoxicity through endoplasmic reticulum stress triggered REDD1-mTOR pathway in breast cancer cells. Anticancer Res 2013; 33: 3807-14.
-
(2013)
Anticancer Res
, vol.33
, pp. 3807-3814
-
-
Lan, Y.-C.1
Chang, C.-L.2
Sung, M.-T.3
-
26
-
-
84874656598
-
Saxifragifolin D induces the interplay between apoptosis and autophagy in breast cancer cells through ROS-dependent endoplasmic reticulum stress
-
Shi JM, Bai LL, Zhang DM et al. Saxifragifolin D induces the interplay between apoptosis and autophagy in breast cancer cells through ROS-dependent endoplasmic reticulum stress. Biochem Pharmacol 2013; 85: 913-26.
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 913-926
-
-
Shi, J.M.1
Bai, L.L.2
Zhang, D.M.3
-
27
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky DJ, Abeliovich H, Agostinis P et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008; 4: 151-75.
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
-
28
-
-
84893675756
-
Autophagy: a critical regulator of cellular metabolism and homeostasis
-
Ryter SW, Cloonan SM, Choi AMK. Autophagy: a critical regulator of cellular metabolism and homeostasis. Mol Cells 2013; 36: 7-16.
-
(2013)
Mol Cells
, vol.36
, pp. 7-16
-
-
Ryter, S.W.1
Cloonan, S.M.2
Choi, A.M.K.3
-
29
-
-
84883282553
-
Role of intracellular calcium in proteasome inhibitor-induced endoplasmic reticulum stress, autophagy, and cell death
-
Williams JA, Hou Y, Ni H-M, Ding W-X. Role of intracellular calcium in proteasome inhibitor-induced endoplasmic reticulum stress, autophagy, and cell death. Pharm Res 2013; 30: 2279-89.
-
(2013)
Pharm Res
, vol.30
, pp. 2279-2289
-
-
Williams, J.A.1
Hou, Y.2
Ni, H.-M.3
Ding, W.-X.4
-
30
-
-
84887999522
-
Nelfinavir and bortezomib inhibit mTOR activity via ATF4-mediated sestrin-2 regulation
-
Bruening A, Rahmeh M, Friese K. Nelfinavir and bortezomib inhibit mTOR activity via ATF4-mediated sestrin-2 regulation. Mol Oncol 2013; 7: 1012-8.
-
(2013)
Mol Oncol
, vol.7
, pp. 1012-1018
-
-
Bruening, A.1
Rahmeh, M.2
Friese, K.3
-
31
-
-
84889636479
-
Phosphoinositide 3-kinases as accelerators and brakes of autophagy
-
O Farrell F, Rusten TE, Stenmark H. Phosphoinositide 3-kinases as accelerators and brakes of autophagy. FEBS J 2013; 280: 6322-37.
-
(2013)
FEBS J
, vol.280
, pp. 6322-6337
-
-
Farrell, O.F.1
Rusten, T.E.2
Stenmark, H.3
-
32
-
-
84868503037
-
Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells
-
Selimovic D, Porzig B, El-Khattouti A et al. Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells. Cell Signal 2013; 25: 308-18.
-
(2013)
Cell Signal
, vol.25
, pp. 308-318
-
-
Selimovic, D.1
Porzig, B.2
El-Khattouti, A.3
-
33
-
-
84874547702
-
Minireview: endoplasmic reticulum stress: control in protein, lipid, and signal homeostasis
-
Mandl J, Meszaros T, Banhegyi G, Csala M. Minireview: endoplasmic reticulum stress: control in protein, lipid, and signal homeostasis. Mol Endocrinol 2013; 27: 384-93.
-
(2013)
Mol Endocrinol
, vol.27
, pp. 384-393
-
-
Mandl, J.1
Meszaros, T.2
Banhegyi, G.3
Csala, M.4
-
35
-
-
84877315340
-
Improvement of ER stress-induced diabetes by stimulating autophagy
-
Bachar-Wikstrom E, Wikstrom JD, Kaiser N, Cerasi E, Leibowitz G. Improvement of ER stress-induced diabetes by stimulating autophagy. Autophagy 2013; 9: 626-8.
-
(2013)
Autophagy
, vol.9
, pp. 626-628
-
-
Bachar-Wikstrom, E.1
Wikstrom, J.D.2
Kaiser, N.3
Cerasi, E.4
Leibowitz, G.5
-
36
-
-
77951228508
-
Hypoxia-induced autophagy: cell death or cell survival?
-
Mazure NM, Pouyssegur J. Hypoxia-induced autophagy: cell death or cell survival? Curr Opin Cell Biol 2010; 22: 177-80.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 177-180
-
-
Mazure, N.M.1
Pouyssegur, J.2
-
37
-
-
84884213364
-
Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine A-induced cell death
-
Ciechomska IA, Gabrusiewicz K, Szczepankiewicz AA, Kaminska B. Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine A-induced cell death. Oncogene 2013; 32: 1518-29.
-
(2013)
Oncogene
, vol.32
, pp. 1518-1529
-
-
Ciechomska, I.A.1
Gabrusiewicz, K.2
Szczepankiewicz, A.A.3
Kaminska, B.4
-
38
-
-
84942910905
-
Selenite-mediated cellular stress, apoptosis, and autophagy in colon cancer cells
-
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Volume 1 - Molecular Mechanisms
-
Rudolf E. Selenite-mediated cellular stress, apoptosis, and autophagy in colon cancer cells. Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Volume 1 - Molecular Mechanisms. 2014; 221-33.
-
(2014)
, pp. 221-233
-
-
Rudolf, E.1
-
39
-
-
76149137386
-
Characterization and antioxidant activity of dihydromyricetin-lecithin complex
-
Liu B, Du J, Zeng J, Chen C, Niu S. Characterization and antioxidant activity of dihydromyricetin-lecithin complex. Eur Food Res Technol 2009; 230: 325-31.
-
(2009)
Eur Food Res Technol
, vol.230
, pp. 325-331
-
-
Liu, B.1
Du, J.2
Zeng, J.3
Chen, C.4
Niu, S.5
-
40
-
-
68049128060
-
Antioxidant and cytotoxic activity of dihydromyricetin from Ampelopsis Grossedentata leaves
-
Zhao L, Wang A, Liu B, Li G, Zhang Z, Chen S. Antioxidant and cytotoxic activity of dihydromyricetin from Ampelopsis Grossedentata leaves. Agro Food Ind Hi Tech 2009; 20: 14-7.
-
(2009)
Agro Food Ind Hi Tech
, vol.20
, pp. 14-17
-
-
Zhao, L.1
Wang, A.2
Liu, B.3
Li, G.4
Zhang, Z.5
Chen, S.6
-
41
-
-
84884538218
-
Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells
-
Poornima P, Weng CF, Padma VV. Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells. Food Chem 2013; 141: 3598-605.
-
(2013)
Food Chem
, vol.141
, pp. 3598-3605
-
-
Poornima, P.1
Weng, C.F.2
Padma, V.V.3
-
42
-
-
84890515810
-
LY294002 and Rapamycin promote coxsackievirus-induced cytopathic effect and apoptosis via inhibition of PI3K/AKT/mTOR signaling pathway
-
Chen Z, Yang L, Liu Y et al. LY294002 and Rapamycin promote coxsackievirus-induced cytopathic effect and apoptosis via inhibition of PI3K/AKT/mTOR signaling pathway. Mol Cell Biochem 2014; 385: 169-77.
-
(2014)
Mol Cell Biochem
, vol.385
, pp. 169-177
-
-
Chen, Z.1
Yang, L.2
Liu, Y.3
-
43
-
-
84876743936
-
Linking membrane dynamics and trafficking to autophagy and the unfolded protein response
-
Chua CEL, Tang BL. Linking membrane dynamics and trafficking to autophagy and the unfolded protein response. J Cell Physiol 2013; 228: 1638-40.
-
(2013)
J Cell Physiol
, vol.228
, pp. 1638-1640
-
-
Chua, C.E.L.1
Tang, B.L.2
-
44
-
-
84873659762
-
Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism implications for breast cancer prevention
-
Sanchez-Alvarez R, Martinez-Outschoorn UE, Lin Z et al. Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism implications for breast cancer prevention. Cell Cycle 2013; 12: 289-301.
-
(2013)
Cell Cycle
, vol.12
, pp. 289-301
-
-
Sanchez-Alvarez, R.1
Martinez-Outschoorn, U.E.2
Lin, Z.3
-
45
-
-
84890068740
-
Depletion of luminal pyridine nucleotides in the endoplasmic reticulum activates autophagy with the involvement of mTOR pathway
-
Kapuy O, Banhegyi G. Depletion of luminal pyridine nucleotides in the endoplasmic reticulum activates autophagy with the involvement of mTOR pathway. Biomed Res Int 2013; 2013: 942431.
-
(2013)
Biomed Res Int
, vol.2013
, pp. 942431
-
-
Kapuy, O.1
Banhegyi, G.2
-
46
-
-
79957634644
-
Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage
-
Dewaele M, Martinet W, Rubio N et al. Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage. J Cell Mol Med 2011; 15: 1402-14.
-
(2011)
J Cell Mol Med
, vol.15
, pp. 1402-1414
-
-
Dewaele, M.1
Martinet, W.2
Rubio, N.3
-
47
-
-
70349645385
-
Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress
-
King FW, Fong S, Griffin C et al. Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress. PLoS One 2009; 4: e7283.
-
(2009)
PLoS One
, vol.4
, pp. e7283
-
-
King, F.W.1
Fong, S.2
Griffin, C.3
|