Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy

Biochemical Pharmacology

Volumn 85, Issue 10, 2013, Pages 1463-1477

  Xi, Haibin ^a,c   Barredo, Julio C ^a,b   Merchan, Jaime R ^a,b   Lampidis, Theodore J ^a,b  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

2 Deoxyglucose; Autophagy; Endoplasmic reticulum stress; Glucose starvation; Hypoxia

Indexed keywords

ADENOSINE TRIPHOSPHATE; AUTOPHAGY PROTEIN 5; BECLIN 1; CALCIUM CALMODULIN DEPENDENT KINASE KINASE BETA; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; DEOXYGLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE LKB1; REACTIVE OXYGEN METABOLITE; TUNICAMYCIN; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL HYPOXIA; CONJUGATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; PANCREAS TUMOR; PRIORITY JOURNAL; PROTEIN DEPLETION;

ADENOSINE TRIPHOSPHATE; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; CELL HYPOXIA; CELL LINE, TUMOR; DEOXYGLUCOSE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUNICAMYCIN;

EID: 84876666017     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.02.037     Document Type: Article

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