-
3
-
-
84858131639
-
Targeting protein-protein interactions and fragment-based drug discovery
-
Valkov E, Sharpe T, Marsh M, et al. Targeting protein-protein interactions and fragment-based drug discovery. Top Curr Chem 2012;317:145-79
-
(2012)
Top Curr Chem
, vol.317
, pp. 145-179
-
-
Valkov, E.1
Sharpe, T.2
Marsh, M.3
-
4
-
-
84857509304
-
Small-molecule stabilization of proteinprotein interactions: An underestimated concept in drug discovery?
-
Thiel P, Kaiser M, Ottmann C. Small-molecule stabilization of proteinprotein interactions: an underestimated concept in drug discovery? Angew Chem 2012;51(9):2012-18
-
(2012)
Angew Chem
, vol.51
, Issue.9
, pp. 2012-2018
-
-
Thiel, P.1
Kaiser, M.2
Ottmann, C.3
-
5
-
-
84866403586
-
Pharmacophore modelling as a virtual screening tool for the discovery of small molecule proteinprotein interaction inhibitors
-
Voet A, Zhang KY. Pharmacophore modelling as a virtual screening tool for the discovery of small molecule proteinprotein interaction inhibitors. Curr Pharm Des 2012;18(30):4586-98
-
(2012)
Curr Pharm des
, vol.18
, Issue.30
, pp. 4586-4598
-
-
Voet, A.1
Zhang, K.Y.2
-
6
-
-
79961187823
-
Pharmaceutical development of biologics: Fundamentals challenges and recent advances
-
Su J, Mazzeo J, Subbarao N, Jin T. Pharmaceutical development of biologics: fundamentals, challenges and recent advances. Ther Deliv 2011;2(7):865-71
-
(2011)
Ther Deliv
, vol.2
, Issue.7
, pp. 865-871
-
-
Su, J.1
Mazzeo, J.2
Subbarao, N.3
Jin, T.4
-
7
-
-
68749083515
-
Roadmap for implementation of quality by design (QbD) for biotechnology products
-
Rathore AS. Roadmap for implementation of quality by design (QbD) for biotechnology products. Trends Biotechnol 2009;27(9):546-53
-
(2009)
Trends Biotechnol
, vol.27
, Issue.9
, pp. 546-553
-
-
Rathore, A.S.1
-
8
-
-
84855740330
-
Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics
-
Kaltashov IA, Bobst CE, Abzalimov RR, et al. Advances and challenges in analytical characterization of biotechnology products: mass spectrometry-based approaches to study properties and behavior of protein therapeutics. Biotechnol Adv 2012;30(1):210-22
-
(2012)
Biotechnol Adv
, vol.30
, Issue.1
, pp. 210-222
-
-
Kaltashov, I.A.1
Bobst, C.E.2
Abzalimov, R.R.3
-
9
-
-
0030463675
-
Analytical methods for the characterization and quality control of pharmaceutical peptides and proteins, using erythropoietin as an example
-
Gilg D, Riedl B, Zier A, Zimmermann MF. Analytical methods for the characterization and quality control of pharmaceutical peptides and proteins, using erythropoietin as an example. Pharm Acta Helv 1996;71(6):383-94
-
(1996)
Pharm Acta Helv
, vol.71
, Issue.6
, pp. 383-394
-
-
Gilg, D.1
Riedl, B.2
Zier, A.3
Zimmermann, M.F.4
-
11
-
-
84855872738
-
Protein instability and immunogenicity: Roadblocks to clinical application of injectable protein delivery systems for sustained release
-
Jiskoot W, Randolph TW, Volkin DB, et al. Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release. J Pharm Sci 2012;101(3):946-54
-
(2012)
J Pharm Sci
, vol.101
, Issue.3
, pp. 946-954
-
-
Jiskoot, W.1
Randolph, T.W.2
Volkin, D.B.3
-
12
-
-
84905001982
-
Controlled ocular drug delivery with nanomicelles
-
Vaishya RD, Khurana V, Patel S, Mitra AK. Controlled ocular drug delivery with nanomicelles. Wiley Interdiscip Rev Nanomed Nanobiotechnol 2014;6(5):422-37
-
(2014)
Wiley Interdiscip Rev Nanomed Nanobiotechnol
, vol.6
, Issue.5
, pp. 422-437
-
-
Vaishya, R.D.1
Khurana, V.2
Patel, S.3
Mitra, A.K.4
-
13
-
-
0033816196
-
Intestinal permeation enhancers
-
Aungst BJ. Intestinal permeation enhancers. J Pharm Sci 2000;89(4):429-42
-
(2000)
J Pharm Sci
, vol.89
, Issue.4
, pp. 429-442
-
-
Aungst, B.J.1
-
14
-
-
84880519156
-
Oral delivery of therapeutic proteins and peptides: A review on recent developments
-
Gupta S, Jain A, Chakraborty M, et al. Oral delivery of therapeutic proteins and peptides: a review on recent developments. Drug Deliv 2013;20(6):237-46
-
(2013)
Drug Deliv
, vol.20
, Issue.6
, pp. 237-246
-
-
Gupta, S.1
Jain, A.2
Chakraborty, M.3
-
15
-
-
84866875931
-
Oral delivery of peptides and proteins using lipid-based drug delivery systems
-
Li P, Nielsen HM, Mullertz A. Oral delivery of peptides and proteins using lipid-based drug delivery systems. Expert Opin Drug Deliv 2012;9(10):1289-304
-
(2012)
Expert Opin Drug Deliv
, vol.9
, Issue.10
, pp. 1289-1304
-
-
Li, P.1
Nielsen, H.M.2
Mullertz, A.3
-
16
-
-
79551683531
-
Oral protein delivery: Current status and future prospect
-
Park K, Kwon IC, Park K. Oral protein delivery: current status and future prospect. Reactive Funct Polym 2011;71(3):280-7
-
(2011)
Reactive Funct Polym
, vol.71
, Issue.3
, pp. 280-287
-
-
Park, K.1
Kwon, I.C.2
Park, K.3
-
17
-
-
84890394930
-
Systemic delivery of biotherapeutics through the lung: Opportunities and challenges for improved lung absorption
-
Sakagami M. Systemic delivery of biotherapeutics through the lung: opportunities and challenges for improved lung absorption. Ther Deliv 2013;4(12):1511-25
-
(2013)
Ther Deliv
, vol.4
, Issue.12
, pp. 1511-1525
-
-
Sakagami, M.1
-
20
-
-
84875038704
-
Development of sustained-release microspheres for the delivery of SAR 1118, an LFA-1 antagonist intended for the treatment of vascular complications of the eye
-
Yandrapu S, Kompella UB. Development of sustained-release microspheres for the delivery of SAR 1118, an LFA-1 antagonist intended for the treatment of vascular complications of the eye. J Ocul Pharmacol Ther 2013;29(2):236-48
-
(2013)
J Ocul Pharmacol Ther
, vol.29
, Issue.2
, pp. 236-248
-
-
Yandrapu, S.1
Kompella, U.B.2
-
21
-
-
79956035553
-
Does process excellence handcuff drug development?
-
Koenig J. Does process excellence handcuff drug development? Drug Discov Today 2011;16(9-10):377-81
-
(2011)
Drug Discov Today
, vol.16
, Issue.9-10
, pp. 377-381
-
-
Koenig, J.1
-
22
-
-
84875737923
-
Injectable implants for the sustained release of protein and peptide drugs
-
Agarwal P, Rupenthal ID. Injectable implants for the sustained release of protein and peptide drugs. Drug Discov Today 2013;18(7-8):337-49
-
(2013)
Drug Discov Today
, vol.18
, Issue.7-8
, pp. 337-349
-
-
Agarwal, P.1
Rupenthal, I.D.2
-
23
-
-
84862652505
-
In situ forming implants-An attractive formulation principle for parenteral depot formulations
-
Kempe S, Mäder K. In situ forming implants-An attractive formulation principle for parenteral depot formulations. J Control Release 2012;161(2):668-79
-
(2012)
J Control Release
, vol.161
, Issue.2
, pp. 668-679
-
-
Kempe, S.1
Mäder, K.2
-
24
-
-
77957346507
-
Biocompatibility of an injectable in situ forming depot for peptide delivery
-
Schoenhammer K, Boisclair J, Schuetz H, et al. Biocompatibility of an injectable in situ forming depot for peptide delivery. J Pharm Sci 2010;99(10):4390-9
-
(2010)
J Pharm Sci
, vol.99
, Issue.10
, pp. 4390-4399
-
-
Schoenhammer, K.1
Boisclair, J.2
Schuetz, H.3
-
25
-
-
70449134629
-
Poly (ethyleneglycol) 500 dimethylether as novel solvent for injectable in situ forming depots
-
Schoenhammer K, Petersen H, Guethlein F, Goepferich A. Poly (ethyleneglycol) 500 dimethylether as novel solvent for injectable in situ forming depots. Pharm Res 2009;26(12):2568-77
-
(2009)
Pharm Res
, vol.26
, Issue.12
, pp. 2568-2577
-
-
Schoenhammer, K.1
Petersen, H.2
Guethlein, F.3
Goepferich, A.4
-
26
-
-
62749195118
-
Injectable in situ forming depot systems: PEG-DAE as novel solvent for improved PLGA storage stability
-
Schoenhammer K, Petersen H, Guethlein F, Goepferich A. Injectable in situ forming depot systems: PEG-DAE as novel solvent for improved PLGA storage stability. Int J Pharm 2009;371(1-2):33-9
-
(2009)
Int J Pharm
, vol.371
, Issue.1-2
, pp. 33-39
-
-
Schoenhammer, K.1
Petersen, H.2
Guethlein, F.3
Goepferich, A.4
-
27
-
-
0034110737
-
Characterization of a polymeric PLGA-injectable implant delivery system for the controlled release of proteins
-
Eliaz RE, Kost J. Characterization of a polymeric PLGA-injectable implant delivery system for the controlled release of proteins. J Biomed Mater Res 2000;50(3):388-96
-
(2000)
J Biomed Mater Res
, vol.50
, Issue.3
, pp. 388-396
-
-
Eliaz, R.E.1
Kost, J.2
-
28
-
-
0032866354
-
Phase inversion dynamics of PLGA solutions related to drug delivery. Part II. The role of solution thermodynamics and bath-side mass transfer
-
Brodbeck KJ, DesNoyer JR, McHugh AJ. Phase inversion dynamics of PLGA solutions related to drug delivery. Part II. The role of solution thermodynamics and bath-side mass transfer. J Control Release 1999;62(3):333-44
-
(1999)
J Control Release
, vol.62
, Issue.3
, pp. 333-344
-
-
Brodbeck, K.J.1
DesNoyer, J.R.2
McHugh, A.J.3
-
29
-
-
0033032661
-
Phase inversion dynamics of PLGA solutions related to drug delivery
-
Graham PD, Brodbeck KJ, McHugh AJ. Phase inversion dynamics of PLGA solutions related to drug delivery. J Control Release 1999;58(2):233-45
-
(1999)
J Control Release
, vol.58
, Issue.2
, pp. 233-245
-
-
Graham, P.D.1
Brodbeck, K.J.2
McHugh, A.J.3
-
30
-
-
0028898243
-
Physico-chemical characterization of a polymeric injectable implant delivery system
-
Shively ML, Coonts BA, Renner WD, et al. Physico-chemical characterization of a polymeric injectable implant delivery system. J Control Release 1995;33(2):237-43
-
(1995)
J Control Release
, vol.33
, Issue.2
, pp. 237-243
-
-
Shively, M.L.1
Coonts, B.A.2
Renner, W.D.3
-
31
-
-
0035936979
-
Role of crystallization in the phase inversion dynamics and protein release kinetics of injectable drug delivery systems
-
DesNoyer JR, McHugh AJ. Role of crystallization in the phase inversion dynamics and protein release kinetics of injectable drug delivery systems. J Control Release 2001;70(3):285-94
-
(2001)
J Control Release
, vol.70
, Issue.3
, pp. 285-294
-
-
DesNoyer, J.R.1
McHugh, A.J.2
-
32
-
-
0027491840
-
A biodegradable injectable implant for delivering micro and macromolecules using poly (lactic-co-glycolic) acid (PLGA) copolymers
-
Shah NH, Railkar AS, Chen FC, et al. A biodegradable injectable implant for delivering micro and macromolecules using poly (lactic-co-glycolic) acid (PLGA) copolymers. J Control Release 1993;27(2):139-47
-
(1993)
J Control Release
, vol.27
, Issue.2
, pp. 139-147
-
-
Shah, N.H.1
Railkar, A.S.2
Chen, F.C.3
-
33
-
-
0033403807
-
Sustained release of human growth hormone from PLGA solution depots
-
Brodbeck KJ, Pushpala S, McHugh AJ. Sustained release of human growth hormone from PLGA solution depots. Pharm Res 1999;16(12):1825-9
-
(1999)
Pharm Res
, vol.16
, Issue.12
, pp. 1825-1829
-
-
Brodbeck, K.J.1
Pushpala, S.2
McHugh, A.J.3
-
34
-
-
0033963035
-
Parameters affecting the efficacy of a sustained release polymeric implant of leuprolide
-
Ravivarapu HB, Moyer KL, Dunn RL. Parameters affecting the efficacy of a sustained release polymeric implant of leuprolide. Int J Pharm 2000;194(2):181-91
-
(2000)
Int J Pharm
, vol.194
, Issue.2
, pp. 181-191
-
-
Ravivarapu, H.B.1
Moyer, K.L.2
Dunn, R.L.3
-
35
-
-
33745422038
-
The influence of surfactant on PLGA microsphere glass transition and water sorption: Remodeling the surface morphology to attenuate the burst release
-
Bouissou C, Rouse JJ, Price R, van der Walle CF. The influence of surfactant on PLGA microsphere glass transition and water sorption: remodeling the surface morphology to attenuate the burst release. Pharm Res 2006;23(6):1295-305
-
(2006)
Pharm Res
, vol.23
, Issue.6
, pp. 1295-1305
-
-
Bouissou, C.1
Rouse, J.J.2
Price, R.3
Van Der Walle, C.F.4
-
36
-
-
0036348297
-
Sustained delivery of human growth hormone from a novel gel system: SABER
-
Okumu FW, Dao le N, Fielder PJ, et al. Sustained delivery of human growth hormone from a novel gel system: SABER. Biomaterials 2002;23(22):4353-8
-
(2002)
Biomaterials
, vol.23
, Issue.22
, pp. 4353-4358
-
-
Okumu, F.W.1
Dao Le, N.2
Fielder, P.J.3
-
37
-
-
1842473797
-
Injectable controlled release formulations incorporating protein crystals
-
Pechenov S, Shenoy B, Yang MX, et al. Injectable controlled release formulations incorporating protein crystals. J Control Release 2004;96(1):149-58
-
(2004)
J Control Release
, vol.96
, Issue.1
, pp. 149-158
-
-
Pechenov, S.1
Shenoy, B.2
Yang, M.X.3
-
38
-
-
29244460647
-
Influence of the poly(lactide-co-glycolide) type on the leuprolide release from in situ forming microparticle systems
-
Luan X, Bodmeier R. Influence of the poly(lactide-co-glycolide) type on the leuprolide release from in situ forming microparticle systems. J Control Release 2006;110(2):266-72
-
(2006)
J Control Release
, vol.110
, Issue.2
, pp. 266-272
-
-
Luan, X.1
Bodmeier, R.2
-
39
-
-
29244464313
-
In situ forming microparticle system for controlled delivery of leuprolide acetate: Influence of the formulation and processing parameters
-
Luan X, Bodmeier R. In situ forming microparticle system for controlled delivery of leuprolide acetate: influence of the formulation and processing parameters. Eur J Pharm Sci 2006;27(2-3):143-9
-
(2006)
Eur J Pharm Sci
, vol.27
, Issue.2-3
, pp. 143-149
-
-
Luan, X.1
Bodmeier, R.2
-
40
-
-
0033844242
-
Controlled release of drugs from injectable in situ formed biodegradable PLGA microspheres: Effect of various formulation variables
-
Jain RA, Rhodes CT, Railkar AM, et al. Controlled release of drugs from injectable in situ formed biodegradable PLGA microspheres: effect of various formulation variables. Eur J Pharm Biopharm 2000;50(2):257-62
-
(2000)
Eur J Pharm Biopharm
, vol.50
, Issue.2
, pp. 257-262
-
-
Jain, R.A.1
Rhodes, C.T.2
Railkar, A.M.3
-
41
-
-
0034009751
-
Controlled delivery of drugs from a novel injectable in situ formed biodegradable PLGA microsphere system
-
Jain RA, Rhodes CT, Railkar AM, et al. Controlled delivery of drugs from a novel injectable in situ formed biodegradable PLGA microsphere system. J Microencapsul 2000;17(3):343-62
-
(2000)
J Microencapsul
, vol.17
, Issue.3
, pp. 343-362
-
-
Jain, R.A.1
Rhodes, C.T.2
Railkar, A.M.3
-
43
-
-
11144341959
-
Triblock copolymers: Syn thesis, characterization, and delivery of a model protein
-
Chen S, Pieper R, Webster DC, Singh J. Triblock copolymers: synthesis, characterization, and delivery of a model protein. Int J Pharm 2005;288(2):207-18
-
(2005)
Int J Pharm
, vol.288
, Issue.2
, pp. 207-218
-
-
Chen, S.1
Pieper, R.2
Webster, D.C.3
Singh, J.4
-
44
-
-
0036060263
-
Thermogelling biodegradable copolymer aqueous solutions for injectable protein delivery and tissue engineering
-
Jeong B, Lee KM, Gutowska A, An YH. Thermogelling biodegradable copolymer aqueous solutions for injectable protein delivery and tissue engineering. Biomacromolecules 2002;3(4):865-8
-
(2002)
Biomacromolecules
, vol.3
, Issue.4
, pp. 865-868
-
-
Jeong, B.1
Lee, K.M.2
Gutowska, A.3
An, Y.H.4
-
45
-
-
0034948794
-
Controlled release of insulin from injectable biodegradable triblock copolymer
-
Kim YJ, Choi S, Koh JJ, et al. Controlled release of insulin from injectable biodegradable triblock copolymer. Pharm Res 2001;18(4):548-50
-
(2001)
Pharm Res
, vol.18
, Issue.4
, pp. 548-550
-
-
Kim, Y.J.1
Choi, S.2
Koh, J.J.3
-
46
-
-
0035858362
-
Biodegradable block copolymers for delivery of proteins and water-insoluble drugs
-
Zentner GM, Rathi R, Shih C, et al. Biodegradable block copolymers for delivery of proteins and water-insoluble drugs. J Control Release 2001;72(1-3):203-15
-
(2001)
J Control Release
, vol.72
, Issue.1-3
, pp. 203-215
-
-
Zentner, G.M.1
Rathi, R.2
Shih, C.3
-
47
-
-
39649106936
-
Controlled release of growth hormone from thermosensitive triblock copolymer systems: In vitro and in vivo evaluation
-
Chen S, Singh J. Controlled release of growth hormone from thermosensitive triblock copolymer systems: in vitro and in vivo evaluation. Int J Pharm 2008;352(1-2):58-65
-
(2008)
Int J Pharm
, vol.352
, Issue.1-2
, pp. 58-65
-
-
Chen, S.1
Singh, J.2
-
48
-
-
77956274928
-
Stabilization of proteins for storage
-
pdb top79
-
Simpson RJ. Stabilization of proteins for storage. Cold Spring Harb protoc 2010;2010(5):pdb top79
-
(2010)
Cold Spring Harb Protoc
, vol.2010
, pp. 5
-
-
Simpson, R.J.1
-
49
-
-
33644533167
-
The effect of solvent environment on the conformation and stability of human polyclonal IgG in solution
-
Szenczi A, Kardos J, Medgyesi GA, Zavodszky P. The effect of solvent environment on the conformation and stability of human polyclonal IgG in solution. Biologicals 2006;34(1):5-14
-
(2006)
Biologicals
, vol.34
, Issue.1
, pp. 5-14
-
-
Szenczi, A.1
Kardos, J.2
Medgyesi, G.A.3
Zavodszky, P.4
-
50
-
-
0141567459
-
Physical stability of proteins in aqueous solution: Mechanism and driving forces in nonnative protein aggregation
-
Chi EY, Krishnan S, Randolph TW, Carpenter JF. Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation. Pharm Res 2003;20(9):1325-36
-
(2003)
Pharm Res
, vol.20
, Issue.9
, pp. 1325-1336
-
-
Chi, E.Y.1
Krishnan, S.2
Randolph, T.W.3
Carpenter, J.F.4
-
51
-
-
84880974502
-
Trehalose limits BSA aggregation in spray-dried formulations at high temperatures: Implications in preparing polymer implants for long-Term protein delivery
-
Rajagopal K, Wood J, Tran B, et al. Trehalose limits BSA aggregation in spray-dried formulations at high temperatures: implications in preparing polymer implants for long-Term protein delivery. J Pharm Sci 2013;102(8):2655-66
-
(2013)
J Pharm Sci
, vol.102
, Issue.8
, pp. 2655-2666
-
-
Rajagopal, K.1
Wood, J.2
Tran, B.3
-
52
-
-
0033635054
-
Protein instability in poly (lactic-co-glycolic acid) microparticles
-
van de Weert M, Hennink WE, Jiskoot W. Protein instability in poly (lactic-co-glycolic acid) microparticles. Pharm Res 2000;17(10):1159-67
-
(2000)
Pharm Res
, vol.17
, Issue.10
, pp. 1159-1167
-
-
Van De Weert, M.1
Hennink, W.E.2
Jiskoot, W.3
-
53
-
-
0036000111
-
Recent advances in the stabilization of proteins encapsulated in injectable PLGA delivery systems
-
Schwendeman SP. Recent advances in the stabilization of proteins encapsulated in injectable PLGA delivery systems. Crit Rev Ther Drug Carrier Syst 2002;19(1):73-98
-
(2002)
Crit Rev Ther Drug Carrier Syst
, vol.19
, Issue.1
, pp. 73-98
-
-
Schwendeman, S.P.1
-
54
-
-
84902359058
-
Tailored protein release from biodegradable poly(epsilon-caprolactone-PEG)-b-poly(epsilon-caprolactone) multiblock-copolymer implants
-
Stankovic M, Tomar J, Hiemstra C, et al. Tailored protein release from biodegradable poly(epsilon-caprolactone-PEG)-b-poly(epsilon-caprolactone) multiblock-copolymer implants. Eur J Pharm Biopharm 2014;87(2):329-37
-
(2014)
Eur J Pharm Biopharm
, vol.87
, Issue.2
, pp. 329-337
-
-
Stankovic, M.1
Tomar, J.2
Hiemstra, C.3
-
55
-
-
84879497613
-
Low temperature extruded implants based on novel hydrophilic multiblock copolymer for long-Term protein delivery
-
Stankovic M, de Waard H, Steendam R, et al. Low temperature extruded implants based on novel hydrophilic multiblock copolymer for long-Term protein delivery. Eur J Pharm Sci 2013;49(4):578-87
-
(2013)
Eur J Pharm Sci
, vol.49
, Issue.4
, pp. 578-587
-
-
Stankovic, M.1
De Waard, H.2
Steendam, R.3
-
56
-
-
77449157990
-
Thermosensitive PCL-PEG-PCL hydrogels: Syn thesis, characterization, and delivery of proteins
-
Ma G, Miao B, Song C. Thermosensitive PCL-PEG-PCL hydrogels: synthesis, characterization, and delivery of proteins. J Appl Polym Sci 2010;116(4):1985-93
-
(2010)
J Appl Polym Sci
, vol.116
, Issue.4
, pp. 1985-1993
-
-
Ma, G.1
Miao, B.2
Song, C.3
-
57
-
-
70349263360
-
Thermosensitive PEG-PCL-PEG hydrogel controlled drug delivery system: Sol-gel-sol transition and in vitro drug release study
-
Gong CY, Dong PW, Shi S, et al. Thermosensitive PEG-PCL-PEG hydrogel controlled drug delivery system: sol-gel-sol transition and in vitro drug release study. J Pharm Sci 2009;98(10):3707-17
-
(2009)
J Pharm Sci
, vol.98
, Issue.10
, pp. 3707-3717
-
-
Gong, C.Y.1
Dong, P.W.2
Shi, S.3
-
58
-
-
68249114966
-
Biodegradable thermogelling hydrogel of P(CL-GL)-PEG-P(CL-GL) triblock copolymer: Degradation and drug release behavior
-
Jiang Z, Hao J, You Y, et al. Biodegradable thermogelling hydrogel of P(CL-GL)-PEG-P(CL-GL) triblock copolymer: degradation and drug release behavior. J Pharm Sci 2009;98(8):2603-10
-
(2009)
J Pharm Sci
, vol.98
, Issue.8
, pp. 2603-2610
-
-
Jiang, Z.1
Hao, J.2
You, Y.3
-
59
-
-
0032699051
-
In vitro properties of an in situ forming gel for the parenteral delivery of macromolecular drugs
-
Joshi R, Robinson DH, Himmelstein KJ. In vitro properties of an in situ forming gel for the parenteral delivery of macromolecular drugs. Pharm Dev Technol 1999;4(4):515-22
-
(1999)
Pharm Dev Technol
, vol.4
, Issue.4
, pp. 515-522
-
-
Joshi, R.1
Robinson, D.H.2
Himmelstein, K.J.3
-
60
-
-
78649724173
-
Tissue integration of growth factoreluting layer-by-layer polyelectrolyte multilayer coated implants
-
Macdonald ML, Samuel RE, Shah NJ, et al. Tissue integration of growth factoreluting layer-by-layer polyelectrolyte multilayer coated implants. Biomaterials 2011;32(5):1446-53
-
(2011)
Biomaterials
, vol.32
, Issue.5
, pp. 1446-1453
-
-
MacDonald, M.L.1
Samuel, R.E.2
Shah, N.J.3
-
61
-
-
84888201490
-
Delivery of a therapeutic protein for bone regeneration from a substrate coated with graphene oxide
-
La WG, Park S, Yoon HH, et al. Delivery of a therapeutic protein for bone regeneration from a substrate coated with graphene oxide. Small 2013;9(23):4051-60
-
(2013)
Small
, vol.9
, Issue.23
, pp. 4051-4060
-
-
La, W.G.1
Park, S.2
Yoon, H.H.3
-
62
-
-
80051550264
-
The performance of BMP-2 loaded TCP/HAP porous ceramics with a polyelectrolyte multilayer film coating
-
Crouzier T, Sailhan F, Becquart P, et al. The performance of BMP-2 loaded TCP/HAP porous ceramics with a polyelectrolyte multilayer film coating. Biomaterials 2011;32(30):7543-54
-
(2011)
Biomaterials
, vol.32
, Issue.30
, pp. 7543-7554
-
-
Crouzier, T.1
Sailhan, F.2
Becquart, P.3
-
63
-
-
84867477914
-
PH-controlled release of proteins from polyelectrolyte-modified anodized titanium surfaces for implant applications
-
Peterson AM, Mohwald H, Shchukin DG. pH-controlled release of proteins from polyelectrolyte-modified anodized titanium surfaces for implant applications. Biomacromolecules 2012;13(10):3120-6
-
(2012)
Biomacromolecules
, vol.13
, Issue.10
, pp. 3120-3126
-
-
Peterson, A.M.1
Mohwald, H.2
Shchukin, D.G.3
-
64
-
-
84894115680
-
Growth factor release from polyelectrolyte-coated titanium for implant applications
-
Peterson AM, Pilz-Allen C, Kolesnikova T, et al. Growth factor release from polyelectrolyte-coated titanium for implant applications. ACS Appl Mater Interfaces 2014;6(3):1866-71
-
(2014)
ACS Appl Mater Interfaces
, vol.6
, Issue.3
, pp. 1866-1871
-
-
Peterson, A.M.1
Pilz-Allen, C.2
Kolesnikova, T.3
-
65
-
-
11144297274
-
Chitosan chemistry and pharmaceutical perspectives
-
Kumar MN, Muzzarelli RA, Muzzarelli C, et al. Chitosan chemistry and pharmaceutical perspectives. Chem Rev 2004;104(12):6017-84
-
(2004)
Chem Rev
, vol.104
, Issue.12
, pp. 6017-6084
-
-
Kumar, M.N.1
Muzzarelli, R.A.2
Muzzarelli, C.3
-
66
-
-
79956084994
-
Hydrogels based on interpenetrating network of chitosan and polyvinyl pyrrolidone for pHsensitive delivery of repaglinide
-
Vaghani SS, Patel MM. Hydrogels based on interpenetrating network of chitosan and polyvinyl pyrrolidone for pHsensitive delivery of repaglinide. Curr Drug Discov Technol 2011;8(2):126-35
-
(2011)
Curr Drug Discov Technol
, vol.8
, Issue.2
, pp. 126-135
-
-
Vaghani, S.S.1
Patel, M.M.2
-
67
-
-
77957307199
-
Tuneable semisynthetic network alginate for absorptive encapsulation and controlled release of protein therapeutics
-
Chan AW, Neufeld RJ. Tuneable semisynthetic network alginate for absorptive encapsulation and controlled release of protein therapeutics. Biomaterials 2010;31(34):9040-7
-
(2010)
Biomaterials
, vol.31
, Issue.34
, pp. 9040-9047
-
-
Chan, A.W.1
Neufeld, R.J.2
-
68
-
-
84901439182
-
PH-Responsive poly(itaconic acid-co-Nvinylpyrrolidone) hydrogels with reduced ionic strength loading solutions offer improved oral delivery potential for high isoelectric point-exhibiting therapeutic proteins
-
Koetting MC, Peppas NA pH-Responsive poly(itaconic acid-co-Nvinylpyrrolidone) hydrogels with reduced ionic strength loading solutions offer improved oral delivery potential for high isoelectric point-exhibiting therapeutic proteins. Int J Pharm 2014;471(1-2):83-91
-
(2014)
Int J Pharm
, vol.471
, Issue.1-2
, pp. 83-91
-
-
Koetting, M.C.1
Peppas, N.A.2
-
69
-
-
0034249313
-
Synthesis and characterization of a novel chitosanbased network prepared using naturally occurring crosslinker
-
Mi F-L, Sung H-W, Shyu S-S. Synthesis and characterization of a novel chitosanbased network prepared using naturally occurring crosslinker. J Polym Sci A 2000;38(15):2804-14
-
(2000)
J Polym Sci A
, vol.38
, Issue.15
, pp. 2804-2814
-
-
Mi, F.-L.1
Sung, H.-W.2
Shyu, S.-S.3
-
70
-
-
55549148731
-
Gamma-irradiated chitosan-polyvinyl pyrrolidone hydrogels as pH-sensitive protein delivery system
-
Dergunov SA, Mun GA. Gamma-irradiated chitosan-polyvinyl pyrrolidone hydrogels as pH-sensitive protein delivery system. Radiat Phys Chem 2009;78(1):65-8
-
(2009)
Radiat Phys Chem
, vol.78
, Issue.1
, pp. 65-68
-
-
Dergunov, S.A.1
Mun, G.A.2
-
72
-
-
33746079628
-
Biodegradability and biocompatibility of a pH-And thermo-sensitive hydrogel formed from a sulfonamide-modified poly(epsilon-caprolactone-co-lactide)-poly (ethylene glycol)-poly(epsiloncaprolactone-co-lactide) block copolymer
-
Shim WS, Kim J-H, Park H, et al. Biodegradability and biocompatibility of a pH-And thermo-sensitive hydrogel formed from a sulfonamide-modified poly(epsilon-caprolactone-co-lactide)-poly (ethylene glycol)-poly(epsiloncaprolactone-co-lactide) block copolymer. Biomaterials 2006;27(30):5178-85
-
(2006)
Biomaterials
, vol.27
, Issue.30
, pp. 5178-5185
-
-
Shim, W.S.1
Kim, J.-H.2
Park, H.3
-
73
-
-
67049162753
-
Injectable in situ-forming pH/thermosensitive hydrogel for bone tissue engineering
-
Kim HK, Shim WS, Kim SE, et al. Injectable in situ-forming pH/thermosensitive hydrogel for bone tissue engineering. Tissue Eng Part A 2009;15(4):923-33
-
(2009)
Tissue Eng Part A
, vol.15
, Issue.4
, pp. 923-933
-
-
Kim, H.K.1
Shim, W.S.2
Kim, S.E.3
-
74
-
-
34247581349
-
Drug release from pHresponsive thermogelling pentablock copolymers
-
Determan MD, Cox JP, Mallapragada SK. Drug release from pHresponsive thermogelling pentablock copolymers. J Biomed Mater Res A 2007;81(2):326-33
-
(2007)
J Biomed Mater Res A
, vol.81
, Issue.2
, pp. 326-333
-
-
Determan, M.D.1
Cox, J.P.2
Mallapragada, S.K.3
-
75
-
-
70449553752
-
Hydrogels of N-isopropylacrylamide copolymers with controlled release of a model protein
-
Milašinović N, Kalagasidis Krušić M, Knežević-Jugović Z, Filipović J. Hydrogels of N-isopropylacrylamide copolymers with controlled release of a model protein. Int J Pharm 2010;383(1-2):53-61
-
(2010)
Int J Pharm
, vol.383
, Issue.1-2
, pp. 53-61
-
-
Milašinović, N.1
Kalagasidis Krušić, M.2
Knežević-Jugović, Z.3
Filipović, J.4
-
76
-
-
84865307480
-
Controlled release of lipase from Candida rugosa loaded into hydrogels of N-isopropylacrylamide and itaconic acid
-
Milašinović N, Knežević-Jugović Z, Milosavljević N, et al. Controlled release of lipase from Candida rugosa loaded into hydrogels of N-isopropylacrylamide and itaconic acid. Int J Pharm 2012;436(1-2):332-40
-
(2012)
Int J Pharm
, vol.436
, Issue.1-2
, pp. 332-340
-
-
Milašinović, N.1
Knežević-Jugović, Z.2
Milosavljević, N.3
-
77
-
-
84884816623
-
Albumin-conjugated pH/thermo responsive poly(amino urethane) multiblock copolymer as an injectable hydrogel for protein delivery
-
Manokruang K, Lee DS. Albumin-conjugated pH/thermo responsive poly(amino urethane) multiblock copolymer as an injectable hydrogel for protein delivery. Macromol Biosci 2013;13(9):1195-203
-
(2013)
Macromol Biosci
, vol.13
, Issue.9
, pp. 1195-1203
-
-
Manokruang, K.1
Lee, D.S.2
-
78
-
-
84907499512
-
Multifunctional interpenetrating polymer network hydrogels based on methacrylated alginate for the delivery of small molecule drugs and sustained release of protein
-
Epub ahead of print]
-
Zhao J, Zhao X, Guo B, Ma PX. Multifunctional interpenetrating polymer network hydrogels based on methacrylated alginate for the delivery of small molecule drugs and sustained release of protein. Biomacromolecules 2014. [Epub ahead of print]
-
(2014)
Biomacromolecules
-
-
Zhao, J.1
Zhao, X.2
Guo, B.3
Ma, P.X.4
-
79
-
-
84887950467
-
Microspheres and microcapsules for protein delivery: Strategies of drug activity retention
-
Wang L, Liu Y, Zhang W, et al. Microspheres and microcapsules for protein delivery: strategies of drug activity retention. Curr Pharm Des 2013;19(35):6340-52
-
(2013)
Curr Pharm des
, vol.19
, Issue.35
, pp. 6340-6352
-
-
Wang, L.1
Liu, Y.2
Zhang, W.3
-
80
-
-
33846138309
-
Controlled delivery of peptides and proteins
-
Degim IT, Celebi N. Controlled delivery of peptides and proteins. Curr Pharm Des 2007;13(1):99-117
-
(2007)
Curr Pharm des
, vol.13
, Issue.1
, pp. 99-117
-
-
Degim, I.T.1
Celebi, N.2
-
81
-
-
0038445582
-
Biodegradable microspheres for protein delivery
-
Sinha VR, Trehan A. Biodegradable microspheres for protein delivery. J control Release 2003;90(3):261-80
-
(2003)
J Control Release
, vol.90
, Issue.3
, pp. 261-280
-
-
Sinha, V.R.1
Trehan, A.2
-
82
-
-
0032078388
-
Recombinant human erythropoietin (rhEPO) loaded poly(lactide-co-glycolide) microspheres: Influence of the encapsulation technique and polymer purity on microsphere characteristics
-
Bittner B, Morlock M, Koll H, et al. Recombinant human erythropoietin (rhEPO) loaded poly(lactide-co-glycolide) microspheres: influence of the encapsulation technique and polymer purity on microsphere characteristics. Eur J Pharm Biopharm 1998;45(3):295-305
-
(1998)
Eur J Pharm Biopharm
, vol.45
, Issue.3
, pp. 295-305
-
-
Bittner, B.1
Morlock, M.2
Koll, H.3
-
83
-
-
15844364250
-
A month-long effect from a single injection of microencapsulated human growth hormone
-
Johnson OL, Cleland JL, Lee HJ, et al. A month-long effect from a single injection of microencapsulated human growth hormone. Nat Med 1996;2(7):795-9
-
(1996)
Nat Med
, vol.2
, Issue.7
, pp. 795-799
-
-
Johnson, O.L.1
Cleland, J.L.2
Lee, H.J.3
-
84
-
-
0035856849
-
Enzyme loaded biodegradable microspheres in vitro ex vivo evaluation
-
Genta I, Perugini P, Pavanetto F, et al. Enzyme loaded biodegradable microspheres in vitro ex vivo evaluation. J Control Release 2001;77(3):287-95
-
(2001)
J Control Release
, vol.77
, Issue.3
, pp. 287-295
-
-
Genta, I.1
Perugini, P.2
Pavanetto, F.3
-
85
-
-
0036159328
-
Oral tolerance induced by poly (lactide-coglycolide) containing B lactoglobulin]
-
Fattal E, Couvreur P, Pecquet S. [Oral tolerance induced by poly (lactide-coglycolide) containing B lactoglobulin]. Ann Pharm Fr 2002;60(1):44-9
-
(2002)
Pharm Fr A.
, vol.60
, Issue.1
, pp. 44-49
-
-
Fattal, E.1
Couvreur, P.2
Pecquet, S.3
-
86
-
-
0036732080
-
Study on biodegradable microspheres containing recombinant interferon-Alpha-2a
-
Zhou S, Deng X, He S, et al. Study on biodegradable microspheres containing recombinant interferon-Alpha-2a. J Pharm Pharmacol 2002;54(9):1287-92
-
(2002)
J Pharm Pharmacol
, vol.54
, Issue.9
, pp. 1287-1292
-
-
Zhou, S.1
Deng, X.2
He, S.3
-
87
-
-
0033781504
-
The stability of insulin in biodegradable microparticles based on blends of lactide polymers and polyethylene glycol
-
Yeh MK. The stability of insulin in biodegradable microparticles based on blends of lactide polymers and polyethylene glycol. J Microencapsul 2000;17(6):743-56
-
(2000)
J Microencapsul
, vol.17
, Issue.6
, pp. 743-756
-
-
Yeh, M.K.1
-
88
-
-
0037133119
-
A novel sustained-release formulation of insulin with dramatic reduction in initial rapid release
-
Takenaga M, Yamaguchi Y, Kitagawa A, et al. A novel sustained-release formulation of insulin with dramatic reduction in initial rapid release. J Control Release 2002;79(1-3):81-91
-
(2002)
J Control Release
, vol.79
, Issue.1-3
, pp. 81-91
-
-
Takenaga, M.1
Yamaguchi, Y.2
Kitagawa, A.3
-
89
-
-
0034756945
-
Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease
-
Lamprecht A, Ubrich N, Yamamoto H, et al. Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease. J Pharmacol Exp Ther 2001;299(2):775-81
-
(2001)
J Pharmacol Exp Ther
, vol.299
, Issue.2
, pp. 775-781
-
-
Lamprecht, A.1
Ubrich, N.2
Yamamoto, H.3
-
90
-
-
0037139386
-
Effects of formulation variables on characteristics of poly (ethylcyanoacrylate) nanocapsules prepared from w/o microemulsions
-
Watnasirichaikul S, Rades T, Tucker IG, Davies NM. Effects of formulation variables on characteristics of poly (ethylcyanoacrylate) nanocapsules prepared from w/o microemulsions. Int J Pharm 2002;235(1-2):237-46
-
(2002)
Int J Pharm
, vol.235
, Issue.1-2
, pp. 237-246
-
-
Watnasirichaikul, S.1
Rades, T.2
Tucker, I.G.3
Davies, N.M.4
-
91
-
-
0030039264
-
Instability of bovine insulin in poly (lactide-co-glycolide) (PLGA) microspheres
-
Uchida T, Yagi A, Oda Y, et al. Instability of bovine insulin in poly (lactide-co-glycolide) (PLGA) microspheres. Chem Pharm Bull(Tokyo) 1996;44(1):235-6
-
(1996)
Chem Pharm Bull(Tokyo)
, vol.44
, Issue.1
, pp. 235-236
-
-
Uchida, T.1
Yagi, A.2
Oda, Y.3
-
92
-
-
0032834111
-
A heterogeneously structured composite based on poly(lactic-co-glycolic acid) microspheres and poly(vinyl alcohol) hydrogel nanoparticles for long-Term protein drug delivery
-
Wang N, Wu XS, Li JK. A heterogeneously structured composite based on poly(lactic-co-glycolic acid) microspheres and poly(vinyl alcohol) hydrogel nanoparticles for long-Term protein drug delivery. Pharm Res 1999;16(9):1430-5
-
(1999)
Pharm Res
, vol.16
, Issue.9
, pp. 1430-1435
-
-
Wang, N.1
Wu, X.S.2
Li, J.K.3
-
93
-
-
0030795050
-
A novel biodegradable system based on gelatin nanoparticles and poly(lactic-co-glycolic acid) microspheres for protein and peptide drug delivery
-
Li JK, Wang N, Wu XS. A novel biodegradable system based on gelatin nanoparticles and poly(lactic-co-glycolic acid) microspheres for protein and peptide drug delivery. J Pharm Sci 1997;86(8):891-5
-
(1997)
J Pharm Sci
, vol.86
, Issue.8
, pp. 891-895
-
-
Li, J.K.1
Wang, N.2
Wu, X.S.3
-
94
-
-
0032473386
-
Formulation of L-Asparaginase-loaded poly(lactide-coglycolide) nanoparticles: Influence of polymer properties on enzyme loading, activity and in vitro release
-
Gasper MM, Blanco D, Cruz ME, Alonso MJ. Formulation of L-Asparaginase-loaded poly(lactide-coglycolide) nanoparticles: influence of polymer properties on enzyme loading, activity and in vitro release. J Control Release 1998;52(1-2):53-62
-
(1998)
J Control Release
, vol.52
, Issue.1-2
, pp. 53-62
-
-
Gasper, M.M.1
Blanco, D.2
Cruz, M.E.3
Alonso, M.J.4
-
95
-
-
0033997473
-
Nanoparticulate delivery system of a tyrphostin for the treatment of restenosis
-
Fishbein I, Chorny M, Rabinovich L, et al. Nanoparticulate delivery system of a tyrphostin for the treatment of restenosis. J Control Release 2000;65(1-2):221-9
-
(2000)
J Control Release
, vol.65
, Issue.1-2
, pp. 221-229
-
-
Fishbein, I.1
Chorny, M.2
Rabinovich, L.3
-
96
-
-
0032863681
-
Pulmonary delivery of insulin with nebulized DL-lactide/ glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect
-
Kawashima Y, Yamamoto H, Takeuchi H, et al. Pulmonary delivery of insulin with nebulized DL-lactide/ glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect. J Control Release 1999;62(1-2):279-87
-
(1999)
J Control Release
, vol.62
, Issue.1-2
, pp. 279-287
-
-
Kawashima, Y.1
Yamamoto, H.2
Takeuchi, H.3
-
98
-
-
84867395808
-
Protein release from poly(lactide-coglycolide) implants prepared by hot-melt extrusion: Thioester formation as a reason for incomplete release
-
Ghalanbor Z, Korber M, Bodmeier R. Protein release from poly(lactide-coglycolide) implants prepared by hot-melt extrusion: thioester formation as a reason for incomplete release. Int J Pharm 2012;438(1-2):302-6
-
(2012)
Int J Pharm
, vol.438
, Issue.1-2
, pp. 302-306
-
-
Ghalanbor, Z.1
Korber, M.2
Bodmeier, R.3
-
99
-
-
84891655460
-
Design and evaluation of a novel nanoparticulate-based formulation encapsulating a HIP complex of lysozyme
-
Gaudana R, Gokulgandhi M, Khurana V, et al. Design and evaluation of a novel nanoparticulate-based formulation encapsulating a HIP complex of lysozyme. Pharm Dev Technol 2013;18(3):752-9
-
(2013)
Pharm Dev Technol
, vol.18
, Issue.3
, pp. 752-759
-
-
Gaudana, R.1
Gokulgandhi, M.2
Khurana, V.3
-
100
-
-
84892478123
-
Encapsulation of proteinpolysaccharide HIP complex in polymeric nanoparticles
-
Gaudana R, Khurana V, Parenky A, Mitra AK. Encapsulation of proteinpolysaccharide HIP complex in polymeric nanoparticles. J Drug Deliv 2011;2011:458128
-
(2011)
J Drug Deliv
, vol.2011
, pp. 458128
-
-
Gaudana, R.1
Khurana, V.2
Parenky, A.3
Mitra, A.K.4
-
101
-
-
78650440780
-
Development and characterization of nanoparticulate formulation of a water soluble prodrug of dexamethasone by HIP complexation
-
Gaudana R, Parenky A, Vaishya R, et al. Development and characterization of nanoparticulate formulation of a water soluble prodrug of dexamethasone by HIP complexation. J Microencapsul 2011;28(1):10-20
-
(2011)
J Microencapsul
, vol.28
, Issue.1
, pp. 10-20
-
-
Gaudana, R.1
Parenky, A.2
Vaishya, R.3
-
102
-
-
84871063912
-
Localized and sustained delivery of fibroblast growth factor-2 from a nanoparticle-hydrogel composite for treatment of spinal cord injury
-
Kang CE, Baumann MD, Tator CH, Shoichet MS. Localized and sustained delivery of fibroblast growth factor-2 from a nanoparticle-hydrogel composite for treatment of spinal cord injury. Cells Tissues Organs 2013;197(1):55-63
-
(2013)
Cells Tissues Organs
, vol.197
, Issue.1
, pp. 55-63
-
-
Kang, C.E.1
Baumann, M.D.2
Tator, C.H.3
Shoichet, M.S.4
-
103
-
-
84917675585
-
Tailor-made pentablock copolymer based formulation for sustained ocular delivery of protein therapeutics
-
In press 105. Mitra AK, Mishra GP. Pentablock polymers. Google Patents 2011; US 20110250283 A1
-
Patel SP, Vaishya R, Mishra GP, et al. Tailor-made pentablock copolymer based formulation for sustained ocular delivery of protein therapeutics. J Drug Deliv 2014; In press 105. Mitra AK, Mishra GP. Pentablock polymers. Google Patents 2011; US 20110250283 A1
-
(2014)
J Drug Deliv
-
-
Patel, S.P.1
Vaishya, R.2
Mishra, G.P.3
-
104
-
-
84929164314
-
Novel pentablock copolymer-based nanoparticulate systems for sustained protein delivery
-
doi:10.1208/s12249-014-0196-6
-
Patel SP, Pal D, Mitra AK. Novel pentablock copolymer-based nanoparticulate systems for sustained protein delivery. AAPS PharmSciTech 2014, doi:10.1208/s12249-014-0196-6
-
(2014)
AAPS PharmSciTech
-
-
Patel, S.P.1
Pal, D.2
Mitra, A.K.3
-
105
-
-
0034702905
-
VEGF gene delivery to myocardium: Deleterious effects of unregulated expression
-
Lee RJ, Springer ML, Blanco-Bose WE, et al. VEGF gene delivery to myocardium: deleterious effects of unregulated expression. Circulation 2000;102(8):898-901
-
(2000)
Circulation
, vol.102
, Issue.8
, pp. 898-901
-
-
Lee, R.J.1
Springer, M.L.2
Blanco-Bose, W.E.3
-
106
-
-
84255172282
-
Sustained release of VEGF from PLGA nanoparticles embedded thermosensitive hydrogel in full-Thickness porcine bladder acellular matrix
-
Geng H, Song H, Qi J, Cui D. Sustained release of VEGF from PLGA nanoparticles embedded thermosensitive hydrogel in full-Thickness porcine bladder acellular matrix. Nanoscale Res Lett 2011;6(1):312
-
(2011)
Nanoscale Res Lett
, vol.6
, Issue.1
, pp. 312
-
-
Geng, H.1
Song, H.2
Qi, J.3
Cui, D.4
-
107
-
-
0020662785
-
Zero-order controlled-release polymer matrices for micro-And macromolecules
-
Hsieh DS, Rhine WD, Langer R. Zero-order controlled-release polymer matrices for micro-And macromolecules. J Pharm Sci 1983;72(1):17-22
-
(1983)
J Pharm Sci
, vol.72
, Issue.1
, pp. 17-22
-
-
Hsieh, D.S.1
Rhine, W.D.2
Langer, R.3
-
108
-
-
0034600194
-
Development of new drug delivery system for protein drugs using silicone I)
-
Kajihara M, Sugie T, Mizuno M, et al. Development of new drug delivery system for protein drugs using silicone (I). J Control Release 2000;66(1):49-61
-
(2000)
J Control Release
, vol.66
, Issue.1
, pp. 49-61
-
-
Kajihara, M.1
Sugie, T.2
Mizuno, M.3
-
109
-
-
0035850216
-
Development of a new drug delivery system for protein drugs using silicone (II)
-
Kajihara M, Sugie T, Hojo T, et al. Development of a new drug delivery system for protein drugs using silicone (II). J Control Release 2001;73(2-3):279-91
-
(2001)
J Control Release
, vol.73
, Issue.2-3
, pp. 279-291
-
-
Kajihara, M.1
Sugie, T.2
Hojo, T.3
-
110
-
-
0037723903
-
Investigation of the release behavior of a covered-rod-Type formulation using silicone
-
Maeda H, Ohashi E, Sano A, et al. Investigation of the release behavior of a covered-rod-Type formulation using silicone. J Control Release 2003;90(1):59-70
-
(2003)
J Control Release
, vol.90
, Issue.1
, pp. 59-70
-
-
Maeda, H.1
Ohashi, E.2
Sano, A.3
-
111
-
-
0037086497
-
Injectable silicone implants as vaccine delivery vehicles
-
Lofthouse SA, Kajihara M, Nagahara S, et al. Injectable silicone implants as vaccine delivery vehicles. Vaccine 2002;20(13-14):1725-32
-
(2002)
Vaccine
, vol.20
, Issue.13-14
, pp. 1725-1732
-
-
Lofthouse, S.A.1
Kajihara, M.2
Nagahara, S.3
-
112
-
-
79851476663
-
DUROS technology delivers peptides and proteins at consistent rate continuously for 3 to 12 months
-
Rohloff CM, Alessi TR, Yang B, et al. DUROS technology delivers peptides and proteins at consistent rate continuously for 3 to 12 months. J Diabetes Sci Tech 2008;2(3):461-7
-
(2008)
J Diabetes Sci Tech
, vol.2
, Issue.3
, pp. 461-467
-
-
Rohloff, C.M.1
Alessi, T.R.2
Yang, B.3
-
113
-
-
0035682063
-
Chronic (60-week) toxicity study of DUROS leuprolide implants in dogs
-
Cukierski MJ, Johnson PA, Beck JC. Chronic (60-week) toxicity study of DUROS leuprolide implants in dogs. Int J Toxicol 2001;20(6):369-81
-
(2001)
Int J Toxicol
, vol.20
, Issue.6
, pp. 369-381
-
-
Cukierski, M.J.1
Johnson, P.A.2
Beck, J.C.3
-
114
-
-
0035838322
-
An in vivo/in vitro comparison with a leuprolide osmotic implant for the treatment of prostate cancer
-
Wright JC, Tao Leonard S, Stevenson CL, et al. An in vivo/in vitro comparison with a leuprolide osmotic implant for the treatment of prostate cancer. J Control Release 2001;75(1-2):1-10
-
(2001)
J Control Release
, vol.75
, Issue.1-2
, pp. 1-10
-
-
Wright, J.C.1
Tao Leonard, S.2
Stevenson, C.L.3
-
115
-
-
0033883540
-
Safety and efficacy of an implantable leuprolide delivery system in patients with advanced prostate cancer
-
Fowler JE Jr, Gottesman JE, Reid CF, et al. Safety and efficacy of an implantable leuprolide delivery system in patients with advanced prostate cancer. J Urol 2000;164(3 Pt 1):730-4
-
(2000)
J Urol
, vol.164
, Issue.3
, pp. 730-734
-
-
Fowler, J.E.1
Gottesman, J.E.2
Reid, C.F.3
-
116
-
-
0034186059
-
Evaluation of an implant that delivers leuprolide for 1 year for the palliative treatment of prostate cancer
-
Fowler JE, Flanagan M, Gleason DM, et al. Evaluation of an implant that delivers leuprolide for 1 year for the palliative treatment of prostate cancer. Urology 2000;55(5):639-42
-
(2000)
Urology
, vol.55
, Issue.5
, pp. 639-642
-
-
Fowler, J.E.1
Flanagan, M.2
Gleason, D.M.3
-
117
-
-
77955954779
-
Critical variables associated with nonbiodegradable osmotically controlled implants
-
Wright JC. Critical variables associated with nonbiodegradable osmotically controlled implants. AAPS J 2010;12(3):437-42
-
(2010)
AAPS J
, vol.12
, Issue.3
, pp. 437-442
-
-
Wright, J.C.1
-
118
-
-
0141818070
-
Pharmacokinetics of an implanted osmotic pump delivering sufentanil for the treatment of chronic pain
-
Fisher DM, Kellett N, Lenhardt R. Pharmacokinetics of an implanted osmotic pump delivering sufentanil for the treatment of chronic pain. Anesthesiology 2003;99(4):929-37
-
(2003)
Anesthesiology
, vol.99
, Issue.4
, pp. 929-937
-
-
Fisher, D.M.1
Kellett, N.2
Lenhardt, R.3
-
120
-
-
79953759344
-
Role of solvation effects in protein denaturation: From thermodynamics to single molecules and back
-
England JL, Haran G. Role of solvation effects in protein denaturation: from thermodynamics to single molecules and back. Annu Rev Phys Chem 2011;62:257-77
-
(2011)
Annu Rev Phys Chem
, vol.62
, pp. 257-277
-
-
England, J.L.1
Haran, G.2
-
121
-
-
84876001560
-
Cosolvent effects on protein stability
-
Canchi DR, Garcia AE. Cosolvent effects on protein stability. Annu Rev Phys Chem 2013;64:273-93
-
(2013)
Annu Rev Phys Chem
, vol.64
, pp. 273-293
-
-
Canchi, D.R.1
Garcia, A.E.2
-
122
-
-
84889255994
-
Nanoparticles in porous microparticles prepared by supercritical infusion and pressure quench technology for sustained delivery of bevacizumab
-
Yandrapu SK, Upadhyay AK, Petrash JM, Kompella UB. Nanoparticles in porous microparticles prepared by supercritical infusion and pressure quench technology for sustained delivery of bevacizumab. Mol Pharm 2013;10(12):4676-86
-
(2013)
Mol Pharm
, vol.10
, Issue.12
, pp. 4676-4686
-
-
Yandrapu, S.K.1
Upadhyay, A.K.2
Petrash, J.M.3
Kompella, U.B.4
-
123
-
-
0035819362
-
Supercritical fluid mixing: Preparation of thermally sensitive polymer composites containing bioactive materials
-
Howdle SM, Watson MS, Whitaker MJ, et al. Supercritical fluid mixing: preparation of thermally sensitive polymer composites containing bioactive materials. Chem Commun 2001;1:109-10
-
(2001)
Chem Commun
, vol.1
, pp. 109-110
-
-
Howdle, S.M.1
Watson, M.S.2
Whitaker, M.J.3
-
124
-
-
84879887394
-
Dual pH-And temperature-responsive microparticles for protein delivery to ischemic tissues
-
Joshi RV, Nelson CE, Poole KM, et al. Dual pH-And temperature-responsive microparticles for protein delivery to ischemic tissues. Acta Biomater 2013;9(5):6526-34
-
(2013)
Acta Biomater
, vol.9
, Issue.5
, pp. 6526-6534
-
-
Joshi, R.V.1
Nelson, C.E.2
Poole, K.M.3
-
125
-
-
4444380534
-
Nanoporous microsystems for islet cell replacement
-
Desai TA, West T, Cohen M, et al. Nanoporous microsystems for islet cell replacement. Adv Drug Deliv Rev 2004;56(11):1661-73
-
(2004)
Adv Drug Deliv Rev
, vol.56
, Issue.11
, pp. 1661-1673
-
-
Desai, T.A.1
West, T.2
Cohen, M.3
-
126
-
-
0036678897
-
Microfabrication technology for pancreatic cell encapsulation
-
Desai TA. Microfabrication technology for pancreatic cell encapsulation. Expert Opin Biol Ther 2002;2(6):633-46
-
(2002)
Expert Opin Biol Ther
, vol.2
, Issue.6
, pp. 633-646
-
-
Desai, T.A.1
-
127
-
-
84881329600
-
Light-Activated in situ forming gel for sustained suprachoroidal delivery of bevacizumab
-
Tyagi P, Barros M, Stansbury JW, Kompella UB. Light-Activated, in situ forming gel for sustained suprachoroidal delivery of bevacizumab. Mol Pharm 2013;10(8):2858-67
-
(2013)
Mol Pharm
, vol.10
, Issue.8
, pp. 2858-2867
-
-
Tyagi, P.1
Barros, M.2
Stansbury, J.W.3
Kompella, U.B.4
-
128
-
-
0035800249
-
Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides
-
Illum L, Fisher AN, Jabbal-Gill I, Davis SS. Bioadhesive starch microspheres and absorption enhancing agents act synergistically to enhance the nasal absorption of polypeptides. Int J Pharm 2001;222(1):109-19
-
(2001)
Int J Pharm
, vol.222
, Issue.1
, pp. 109-119
-
-
Illum, L.1
Fisher, A.N.2
Jabbal-Gill, I.3
Davis, S.S.4
-
129
-
-
0026417452
-
Coated alginate microspheres: Factors influencing the controlled delivery of macromolecules
-
Wheatley MA, Chang M, Park E, Langer R. Coated alginate microspheres: factors influencing the controlled delivery of macromolecules. J Appl Polym Sci 1991;43(11):2123-35
-
(1991)
J Appl Polym Sci
, vol.43
, Issue.11
, pp. 2123-2135
-
-
Wheatley, M.A.1
Chang, M.2
Park, E.3
Langer, R.4
-
130
-
-
0141961726
-
Chitin/ PLGA blend microspheres as a biodegradable drug delivery system: A new delivery system for protein
-
Mi FL, Shyu SS, Lin YM, et al. Chitin/ PLGA blend microspheres as a biodegradable drug delivery system: a new delivery system for protein. Biomaterials 2003;24(27):5023-36
-
(2003)
Biomaterials
, vol.24
, Issue.27
, pp. 5023-5036
-
-
Mi, F.L.1
Shyu, S.S.2
Lin, Y.M.3
-
131
-
-
1842452953
-
Chitosan microspheres as a potential carrier for drugs
-
Sinha VR, Singla AK, Wadhawan S, et al. Chitosan microspheres as a potential carrier for drugs. Int J Pharm 2004;274(1-2):1-33
-
(2004)
Int J Pharm
, vol.274
, Issue.1-2
, pp. 1-33
-
-
Sinha, V.R.1
Singla, A.K.2
Wadhawan, S.3
-
132
-
-
0242289317
-
Studies on the microspheres comprised of reconstituted collagen and hydroxyapatite
-
Wu TJ, Huang HH, Lan CW, et al. Studies on the microspheres comprised of reconstituted collagen and hydroxyapatite. Biomaterials 2004;25(4):651-8
-
(2004)
Biomaterials
, vol.25
, Issue.4
, pp. 651-658
-
-
Wu, T.J.1
Huang, H.H.2
Lan, C.W.3
-
133
-
-
2942613581
-
Microspheres of corn protein, zein, for an ivermectin drug delivery system
-
Liu X, Sun Q, Wang H, et al. Microspheres of corn protein, zein, for an ivermectin drug delivery system. Biomaterials 2005;26(1):109-15
-
(2005)
Biomaterials
, vol.26
, Issue.1
, pp. 109-115
-
-
Liu, X.1
Sun, Q.2
Wang, H.3
-
134
-
-
0027162035
-
Oral immunization of rats with proteinoid microspheres encapsulating influenza virus antigens
-
Santiago N, Milstein S, Rivera T, et al. Oral immunization of rats with proteinoid microspheres encapsulating influenza virus antigens. Pharm Res 1993;10(8):1243-7
-
(1993)
Pharm Res
, vol.10
, Issue.8
, pp. 1243-1247
-
-
Santiago, N.1
Milstein, S.2
Rivera, T.3
-
135
-
-
2942748422
-
Characterization of protein release from photocrosslinkable hyaluronic acidpolyethylene glycol hydrogel tissue engineering scaffolds
-
Leach JB, Schmidt CE. Characterization of protein release from photocrosslinkable hyaluronic acidpolyethylene glycol hydrogel tissue engineering scaffolds. Biomaterials 2005;26(2):125-35
-
(2005)
Biomaterials
, vol.26
, Issue.2
, pp. 125-135
-
-
Leach, J.B.1
Schmidt, C.E.2
-
136
-
-
0027793235
-
Osteogenic activity of bone morphogenetic protein and hydroxyapatite composite implants
-
Herr G, Wahl D, Kusswetter W. Osteogenic activity of bone morphogenetic protein and hydroxyapatite composite implants. Ann Chir Gynaecol Suppl 1993;207:99-107
-
(1993)
Ann Chir Gynaecol Suppl
, vol.207
, pp. 99-107
-
-
Herr, G.1
Wahl, D.2
Kusswetter, W.3
-
137
-
-
1642331315
-
Calcium phosphate-Alginate microspheres as enzyme delivery matrices
-
Ribeiro CC, Barrias CC, Barbosa MA. Calcium phosphate-Alginate microspheres as enzyme delivery matrices. Biomaterials 2004;25(18):4363-73
-
(2004)
Biomaterials
, vol.25
, Issue.18
, pp. 4363-4373
-
-
Ribeiro, C.C.1
Barrias, C.C.2
Barbosa, M.A.3
-
138
-
-
0035287318
-
Delivery systems for penetration enhancement of peptide and protein drugs: Design considerations
-
Kompella UB, Lee VH. Delivery systems for penetration enhancement of peptide and protein drugs: design considerations. Adv Drug Deliv Rev 2001;46(1-3):211-45
-
(2001)
Adv Drug Deliv Rev
, vol.46
, Issue.1-3
, pp. 211-245
-
-
Kompella, U.B.1
Lee, V.H.2
-
139
-
-
2342435756
-
Synthesis and characterization of partially biodegradable, temperature and pH sensitive Dex-MA/PNIPAAm hydrogels
-
Zhang X, Wu D, Chu CC. Synthesis and characterization of partially biodegradable, temperature and pH sensitive Dex-MA/PNIPAAm hydrogels. Biomaterials 2004;25(19):4719-30
-
(2004)
Biomaterials
, vol.25
, Issue.19
, pp. 4719-4730
-
-
Zhang, X.1
Wu, D.2
Chu, C.C.3
-
140
-
-
0346104839
-
Microsphere size, precipitation kinetics and drug distribution control drug release from biodegradable polyanhydride microspheres
-
Berkland C, Kipper MJ, Narasimhan B, et al. Microsphere size, precipitation kinetics and drug distribution control drug release from biodegradable polyanhydride microspheres. J Control Release 2004;94(1):129-41
-
(2004)
J Control Release
, vol.94
, Issue.1
, pp. 129-141
-
-
Berkland, C.1
Kipper, M.J.2
Narasimhan, B.3
-
141
-
-
2142768756
-
Importance of single or blended polymer types for controlled in vitro release and plasma levels of a somatostatin analogue entrapped in PLA/ PLGA microspheres
-
Blanco-Prieto MJ, Campanero MA, Besseghir K, et al. Importance of single or blended polymer types for controlled in vitro release and plasma levels of a somatostatin analogue entrapped in PLA/ PLGA microspheres. J Control Release 2004;96(3):437-48
-
(2004)
J Control Release
, vol.96
, Issue.3
, pp. 437-448
-
-
Blanco-Prieto, M.J.1
Campanero, M.A.2
Besseghir, K.3
-
142
-
-
0035838367
-
Auto-catalyzed poly(ortho ester) microspheres: A study of their erosion and drug release mechanism
-
Chia HH, Yang YY, Chung TS, et al. Auto-catalyzed poly(ortho ester) microspheres: a study of their erosion and drug release mechanism. J Control Release 2001;75(1-2):11-25
-
(2001)
J Control Release
, vol.75
, Issue.1-2
, pp. 11-25
-
-
Chia, H.H.1
Yang, Y.Y.2
Chung, T.S.3
-
143
-
-
0037122774
-
A synthetic polymer matrix for the delayed or pulsatile release of water-soluble peptides
-
Schachter DM, Kohn J. A synthetic polymer matrix for the delayed or pulsatile release of water-soluble peptides. J Control Release 2002;78(1-3):143-53
-
(2002)
J Control Release
, vol.78
, Issue.1-3
, pp. 143-153
-
-
Schachter, D.M.1
Kohn, J.2
-
144
-
-
2442716075
-
Poly-epsilon-caprolactone microspheres and nanospheres: An overview
-
Sinha VR, Bansal K, Kaushik R, et al. Poly-epsilon-caprolactone microspheres and nanospheres: an overview. Int J Pharm 2004;278(1):1-23
-
(2004)
Int J Pharm
, vol.278
, Issue.1
, pp. 1-23
-
-
Sinha, V.R.1
Bansal, K.2
Kaushik, R.3
-
145
-
-
0037148656
-
Poly (ethylene oxide)-block-poly(L-Amino acid) micelles for drug delivery
-
Lavasanifar A, Samuel J, Kwon GS. Poly (ethylene oxide)-block-poly(L-Amino acid) micelles for drug delivery. Adv Drug Deliv Rev 2002;54(2):169-90
-
(2002)
Adv Drug Deliv Rev
, vol.54
, Issue.2
, pp. 169-190
-
-
Lavasanifar, A.1
Samuel, J.2
Kwon, G.S.3
-
146
-
-
0037466410
-
Biodegradable polyphosphazenes for drug delivery applications
-
Lakshmi S, Katti DS, Laurencin CT. Biodegradable polyphosphazenes for drug delivery applications. Adv Drug Deliv Rev 2003;55(4):467-82
-
(2003)
Adv Drug Deliv Rev
, vol.55
, Issue.4
, pp. 467-482
-
-
Lakshmi, S.1
Katti, D.S.2
Laurencin, C.T.3
-
147
-
-
0032584058
-
Polyorganophosphazene microspheres for drug release: Polymer syn thesis, microsphere preparation, in vitro and in vivo naproxen release
-
Veronese FM, Marsilio F, Caliceti P, et al. Polyorganophosphazene microspheres for drug release: polymer synthesis, microsphere preparation, in vitro and in vivo naproxen release. J Control Release 1998;52(3):227-37
-
(1998)
J Control Release
, vol.52
, Issue.3
, pp. 227-237
-
-
Veronese, F.M.1
Marsilio, F.2
Caliceti, P.3
-
148
-
-
31144447377
-
Stabilization and encapsulation of a staphylokinase variant (K35R) into poly (lactic-co-glycolic acid) microspheres
-
He JT, Su HB, Li GP, et al. Stabilization and encapsulation of a staphylokinase variant (K35R) into poly (lactic-co-glycolic acid) microspheres. Int J Pharm 2006;309(1-2):101-8
-
(2006)
Int J Pharm
, vol.309
, Issue.1-2
, pp. 101-108
-
-
He, J.T.1
Su, H.B.2
Li, G.P.3
-
149
-
-
67649236178
-
Controlled delivery of heat shock protein using an injectable microsphere/hydrogel combination system for the treatment of myocardial infarction
-
Lee J, Tan CY, Lee SK, et al. Controlled delivery of heat shock protein using an injectable microsphere/hydrogel combination system for the treatment of myocardial infarction. J Control Release 2009;137(3):196-202
-
(2009)
J Control Release
, vol.137
, Issue.3
, pp. 196-202
-
-
Lee, J.1
Tan, C.Y.2
Lee, S.K.3
-
150
-
-
67349225348
-
Injectable microsphere/ hydrogel combination systems for localized protein delivery
-
Lee J, Lee KY. Injectable microsphere/ hydrogel combination systems for localized protein delivery. Macromol Biosci 2009;9(7):671-6
-
(2009)
Macromol Biosci
, vol.9
, Issue.7
, pp. 671-676
-
-
Lee, J.1
Lee, K.Y.2
-
151
-
-
0032078351
-
Protein encapsulation and release from poly (lactide-co-glycolide) microspheres: Effect of the protein and polymer properties and of the co-encapsulation of surfactants
-
Blanco D, Alonso MJ. Protein encapsulation and release from poly (lactide-co-glycolide) microspheres: effect of the protein and polymer properties and of the co-encapsulation of surfactants. Eur J Pharm Biopharm 1998;45(3):285-94
-
(1998)
Eur J Pharm Biopharm
, vol.45
, Issue.3
, pp. 285-294
-
-
Blanco, D.1
Alonso, M.J.2
-
152
-
-
0036247441
-
The mechanism of PLA microparticle formation by water-in-oil-in-water solvent evaporation method
-
Chen JL, Chiang CH, Yeh MK. The mechanism of PLA microparticle formation by water-in-oil-in-water solvent evaporation method. J Microencapsul 2002;19(3):333-46
-
(2002)
J Microencapsul
, vol.19
, Issue.3
, pp. 333-346
-
-
Chen, J.L.1
Chiang, C.H.2
Yeh, M.K.3
-
153
-
-
33646766149
-
Influences of excipients on in vitro release and in vivo performance of tetanus toxoid loaded polymer particles
-
Katare YK, Panda AK. Influences of excipients on in vitro release and in vivo performance of tetanus toxoid loaded polymer particles. Eur J Pharm Sci 2006;28(3):179-88
-
(2006)
Eur J Pharm Sci
, vol.28
, Issue.3
, pp. 179-188
-
-
Katare, Y.K.1
Panda, A.K.2
-
154
-
-
33746197968
-
Preparation of insulin-loaded PLA/ PLGA microcapsules by a novel membrane emulsification method and its release in vitro
-
Liu R, Huang SS, Wan YH, et al. Preparation of insulin-loaded PLA/ PLGA microcapsules by a novel membrane emulsification method and its release in vitro. Colloids Surf B Biointerfaces 2006;51(1):30-8
-
(2006)
Colloids Surf B Biointerfaces
, vol.51
, Issue.1
, pp. 30-38
-
-
Liu, R.1
Huang, S.S.2
Wan, Y.H.3
-
155
-
-
0035115117
-
Preparation and characterization of hCGloaded polylactide or poly(lactide-coglycolide) microspheres using a modified water-in-oil-in-water (w/o/w) emulsion solvent evaporation technique
-
Zhu KJ, Jiang HL, Du XY, et al. Preparation and characterization of hCGloaded polylactide or poly(lactide-coglycolide) microspheres using a modified water-in-oil-in-water (w/o/w) emulsion solvent evaporation technique. J Microencapsul 2001;18(2):247-60
-
(2001)
J Microencapsul
, vol.18
, Issue.2
, pp. 247-260
-
-
Zhu, K.J.1
Jiang, H.L.2
Du, X.Y.3
-
156
-
-
1842865844
-
Effect of osmotic pressure in the solvent extraction phase on BSA release profile from PLGA microspheres
-
Jiang G, Thanoo BC, DeLuca PP. Effect of osmotic pressure in the solvent extraction phase on BSA release profile from PLGA microspheres. Pharm Dev Technol 2002;7(4):391-9
-
(2002)
Pharm Dev Technol
, vol.7
, Issue.4
, pp. 391-399
-
-
Jiang, G.1
Thanoo, B.C.2
Deluca, P.P.3
-
157
-
-
70449641609
-
Dermatan sulfate as a stabilizer for protein stability in poly (lactide-co-glycolide) depot
-
Park W, Na K. Dermatan sulfate as a stabilizer for protein stability in poly (lactide-co-glycolide) depot. Biotechnol Bioproc Eng 2009;14(5):668-74
-
(2009)
Biotechnol Bioproc Eng
, vol.14
, Issue.5
, pp. 668-674
-
-
Park, W.1
Na, K.2
-
158
-
-
67349232458
-
Polyelectrolyte complex of chondroitin sulfate and peptide with lower pI value in poly(lactide-coglycolide) microsphere for stability and controlled release
-
Park W, Na K. Polyelectrolyte complex of chondroitin sulfate and peptide with lower pI value in poly(lactide-coglycolide) microsphere for stability and controlled release. Colloids Surf B Biointerfaces 2009;72(2):193-200
-
(2009)
Colloids Surf B Biointerfaces
, vol.72
, Issue.2
, pp. 193-200
-
-
Park, W.1
Na, K.2
-
159
-
-
0035839179
-
Preparation and evaluation of poly(Llactic acid) microspheres containing rhEGF for chronic gastric ulcer healing
-
Han K, Lee KD, Gao ZG, Park JS. Preparation and evaluation of poly(Llactic acid) microspheres containing rhEGF for chronic gastric ulcer healing. J Control Release 2001;75(3):259-69
-
(2001)
J Control Release
, vol.75
, Issue.3
, pp. 259-269
-
-
Han, K.1
Lee, K.D.2
Gao, Z.G.3
Park, J.S.4
-
160
-
-
55149103113
-
Recombinant interferon-Alpha2b poly (lactic-co-glycolic acid) microspheres: Pharmacokinetics-pharmacodynamics study in rhesus monkeys following intramuscular administration
-
Zhang YM, Yang F, Yang YQ, et al. Recombinant interferon-Alpha2b poly (lactic-co-glycolic acid) microspheres: pharmacokinetics-pharmacodynamics study in rhesus monkeys following intramuscular administration. Acta Pharmacol Sin 2008;29(11):1370-5
-
(2008)
Acta Pharmacol Sin
, vol.29
, Issue.11
, pp. 1370-1375
-
-
Zhang, Y.M.1
Yang, F.2
Yang, Y.Q.3
-
161
-
-
43249083134
-
Gamma-irradiation effects on biopharmaceutical properties of PLGA microspheres loaded with SPf66 synthetic vaccine
-
Igartua M, Hernandez RM, Rosas JE, et al. Gamma-irradiation effects on biopharmaceutical properties of PLGA microspheres loaded with SPf66 synthetic vaccine. Eur J Pharm Biopharm 2008;69(2):519-26
-
(2008)
Eur J Pharm Biopharm
, vol.69
, Issue.2
, pp. 519-526
-
-
Igartua, M.1
Hernandez, R.M.2
Rosas, J.E.3
-
162
-
-
71249159143
-
A spheres-in-sphere structure for improving protein-loading poly (lactideco-glycolide) microspheres
-
Wang M, Feng Q, Niu X, et al. A spheres-in-sphere structure for improving protein-loading poly (lactideco-glycolide) microspheres. Polym Degradation Stability 2010;95(1):6-13
-
(2010)
Polym Degradation Stability
, vol.95
, Issue.1
, pp. 6-13
-
-
Wang, M.1
Feng, Q.2
Niu, X.3
-
163
-
-
64849087911
-
Biocompatible microspheres based on acetylated polysaccharide prepared from water-inoil-in-water (W1/O/W2) doubleemulsion method for delivery of type II diabetic drug (exenatide)
-
Yang HJ, Park IS, Na K. Biocompatible microspheres based on acetylated polysaccharide prepared from water-inoil-in-water (W1/O/W2) doubleemulsion method for delivery of type II diabetic drug (exenatide). Colloids Surf A Physicochem Eng Asp 2009;340(1-3):115-20
-
(2009)
Colloids Surf A Physicochem Eng Asp
, vol.340
, Issue.1-3
, pp. 115-120
-
-
Yang, H.J.1
Park, I.S.2
Na, K.3
-
164
-
-
33750706545
-
In vitro study of lysozyme in poly(lactide-coglycolide) microspheres with sucrose acetate isobutyrate
-
Lee ES, Kwon MJ, Lee H, et al. In vitro study of lysozyme in poly(lactide-coglycolide) microspheres with sucrose acetate isobutyrate. Eur J Pharm Sci 2006;29(5):435-41
-
(2006)
Eur J Pharm Sci
, vol.29
, Issue.5
, pp. 435-441
-
-
Lee, E.S.1
Kwon, M.J.2
Lee, H.3
-
165
-
-
84881333236
-
Sustained release of matrix metalloproteinase-3 to trabecular meshwork cells using biodegradable PLGA microparticles
-
Turturro S, Sunoqrot S, Ying H, et al. Sustained release of matrix metalloproteinase-3 to trabecular meshwork cells using biodegradable PLGA microparticles. Mol Pharm 2013;10(8):3023-32
-
(2013)
Mol Pharm
, vol.10
, Issue.8
, pp. 3023-3032
-
-
Turturro, S.1
Sunoqrot, S.2
Ying, H.3
-
166
-
-
84866064086
-
Effects of erythropoietin-dextran microparticlebased PLGA/PLA microspheres on RGCs
-
Rong X, Yang S, Miao H, et al. Effects of erythropoietin-dextran microparticlebased PLGA/PLA microspheres on RGCs. Invest Ophthalmol Vis Sci 2012;53(10):6025-34
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, Issue.10
, pp. 6025-6034
-
-
Rong, X.1
Yang, S.2
Miao, H.3
-
167
-
-
11244316628
-
Improvement of protein loading and modulation of protein release from poly (lactide-co-glycolide) microspheres by complexation of proteins with polyanions
-
Jiang HL, Jin JF, Hu YQ, Zhu KJ. Improvement of protein loading and modulation of protein release from poly (lactide-co-glycolide) microspheres by complexation of proteins with polyanions. J Microencapsul 2004;21(6):615-24
-
(2004)
J Microencapsul
, vol.21
, Issue.6
, pp. 615-624
-
-
Jiang, H.L.1
Jin, J.F.2
Hu, Y.Q.3
Zhu, K.J.4
-
168
-
-
33645961580
-
Effect of cyclodextrins on alphachymotrypsin stability and loading in PLGA microspheres upon S/O/W encapsulation
-
Castellanos IJ, Flores G, Griebenow K. Effect of cyclodextrins on alphachymotrypsin stability and loading in PLGA microspheres upon S/O/W encapsulation. J Pharm Sci 2006;95(4):849-58
-
(2006)
J Pharm Sci
, vol.95
, Issue.4
, pp. 849-858
-
-
Castellanos, I.J.1
Flores, G.2
Griebenow, K.3
-
169
-
-
0037423787
-
Sustained release of human growth hormone from microcapsules prepared by a solvent evaporation technique
-
Takada S, Yamagata Y, Misaki M, et al. Sustained release of human growth hormone from microcapsules prepared by a solvent evaporation technique. J control Release 2003;88(2):229-42
-
(2003)
J Control Release
, vol.88
, Issue.2
, pp. 229-242
-
-
Takada, S.1
Yamagata, Y.2
Misaki, M.3
-
170
-
-
58149152977
-
Development of protein delivery microsphere system by a novel S/O/O/W multi-emulsion
-
Yuan W, Wu F, Guo M, Jin T. Development of protein delivery microsphere system by a novel S/O/O/W multi-emulsion. Eur J Pharm Sci 2009;36(2-3):212-18
-
(2009)
Eur J Pharm Sci
, vol.36
, Issue.2-3
, pp. 212-218
-
-
Yuan, W.1
Wu, F.2
Guo, M.3
Jin, T.4
-
171
-
-
0037436016
-
Poly(ethylene glycol) as stabilizer and emulsifying agent: A novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible polyester microspheres
-
Castellanos IJ, Crespo R, Griebenow K. Poly(ethylene glycol) as stabilizer and emulsifying agent: a novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible polyester microspheres. J Control Release 2003;88(1):135-45
-
(2003)
J Control Release
, vol.88
, Issue.1
, pp. 135-145
-
-
Castellanos, I.J.1
Crespo, R.2
Griebenow, K.3
-
172
-
-
0037124470
-
Insulin-loaded biodegradable PLGA microcapsules: Initial burst release controlled by hydrophilic additives
-
Yamaguchi Y, Takenaga M, Kitagawa A, et al. Insulin-loaded biodegradable PLGA microcapsules: initial burst release controlled by hydrophilic additives. J Control Release 2002;81(3):235-49
-
(2002)
J Control Release
, vol.81
, Issue.3
, pp. 235-249
-
-
Yamaguchi, Y.1
Takenaga, M.2
Kitagawa, A.3
-
173
-
-
0033661972
-
Preparation, characterization, and in vitro evaluation of 1-And 4-month controlled release orntide PLA and PLGA microspheres
-
Kostanski JW, Thanoo BC, DeLuca PP. Preparation, characterization, and in vitro evaluation of 1-And 4-month controlled release orntide PLA and PLGA microspheres. Pharm Dev Technol 2000;5(4):585-96
-
(2000)
Pharm Dev Technol
, vol.5
, Issue.4
, pp. 585-596
-
-
Kostanski, J.W.1
Thanoo, B.C.2
Deluca, P.P.3
-
174
-
-
0034602599
-
Protein encapsulation into biodegradable microspheres by a novel S/O/W emulsion method using poly(ethylene glycol) as a protein micronization adjuvant
-
Morita T, Sakamura Y, Horikiri Y, et al. Protein encapsulation into biodegradable microspheres by a novel S/O/W emulsion method using poly(ethylene glycol) as a protein micronization adjuvant. J Control Release 2000;69(3):435-44
-
(2000)
J Control Release
, vol.69
, Issue.3
, pp. 435-444
-
-
Morita, T.1
Sakamura, Y.2
Horikiri, Y.3
-
175
-
-
0035839191
-
Preparation, characterization and in vivo evaluation of 120-day poly(D,Llactide) leuprolide microspheres
-
Woo BH, Kostanski JW, Gebrekidan S, et al. Preparation, characterization and in vivo evaluation of 120-day poly(D,Llactide) leuprolide microspheres. J Control Release 2001;75(3):307-15
-
(2001)
J Control Release
, vol.75
, Issue.3
, pp. 307-315
-
-
Woo, B.H.1
Kostanski, J.W.2
Gebrekidan, S.3
-
176
-
-
58149166741
-
Novel composite microparticles for protein stabilization and delivery
-
Schoubben A, Blasi P, Giovagnoli S, et al. Novel composite microparticles for protein stabilization and delivery. Eur J Pharm Sci 2009;36(2-3):226-34
-
(2009)
Eur J Pharm Sci
, vol.36
, Issue.2-3
, pp. 226-234
-
-
Schoubben, A.1
Blasi, P.2
Giovagnoli, S.3
-
177
-
-
0032956055
-
A novel system based on a poloxamer/ PLGA blend as a tetanus toxoid delivery vehicle
-
Tobio M, Nolley J, Guo Y, et al. A novel system based on a poloxamer/ PLGA blend as a tetanus toxoid delivery vehicle. Pharm Res 1999;16(5):682-8
-
(1999)
Pharm Res
, vol.16
, Issue.5
, pp. 682-688
-
-
Tobio, M.1
Nolley, J.2
Guo, Y.3
-
178
-
-
65949087875
-
A novel approach to prepare insulin-loaded poly(lactic-coglycolic acid) microcapsules and the protein stability study
-
Emami J, Hamishehkar H, Najafabadi AR, et al. A novel approach to prepare insulin-loaded poly(lactic-coglycolic acid) microcapsules and the protein stability study. J Pharm Sci 2009;98(5):1712-31
-
(2009)
J Pharm Sci
, vol.98
, Issue.5
, pp. 1712-1731
-
-
Emami, J.1
Hamishehkar, H.2
Najafabadi, A.R.3
-
179
-
-
0034057557
-
Comparison of various injectable proteinloaded biodegradable poly(lactide-coglycolide) (PLGA) devices: In-situ-formed implant versus in-situ-formed microspheres versus isolated microspheres
-
Jain RA, Rhodes CT, Railkar AM, et al. Comparison of various injectable proteinloaded biodegradable poly(lactide-coglycolide) (PLGA) devices: in-situ-formed implant versus in-situ-formed microspheres versus isolated microspheres. Pharm Dev Technol 2000;5(2):201-7
-
(2000)
Pharm Dev Technol
, vol.5
, Issue.2
, pp. 201-207
-
-
Jain, R.A.1
Rhodes, C.T.2
Railkar, A.M.3
-
180
-
-
33645516939
-
Encapsulation of protein nanoparticles into uniform-sized microspheres formed in a spinning oil film
-
Leach WT, Simpson DT, Val TN, et al. Encapsulation of protein nanoparticles into uniform-sized microspheres formed in a spinning oil film. AAPS PharmSciTech 2005;6(4):E605-17
-
(2005)
AAPS PharmSciTech
, vol.6
, Issue.4
, pp. E605-E617
-
-
Leach, W.T.1
Simpson, D.T.2
Val, T.N.3
-
181
-
-
60649118338
-
Sustained delivery of endostatin improves the efficacy of therapy in Lewis lung cancer model
-
Wu J, Ding D, Ren G, et al. Sustained delivery of endostatin improves the efficacy of therapy in Lewis lung cancer model. J Control Release 2009;134(2):91-7
-
(2009)
J Control Release
, vol.134
, Issue.2
, pp. 91-97
-
-
Wu, J.1
Ding, D.2
Ren, G.3
-
182
-
-
67049162364
-
Microspheres made by w/o/o emulsion method with reduced initial burst for long-Term delivery of endostar, a novel recombinant human endostatin
-
Wu J, Wu L, Xu X, et al. Microspheres made by w/o/o emulsion method with reduced initial burst for long-Term delivery of endostar, a novel recombinant human endostatin. J Pharm Sci 2009;98(6):2051-8
-
(2009)
J Pharm Sci
, vol.98
, Issue.6
, pp. 2051-2058
-
-
Wu, J.1
Wu, L.2
Xu, X.3
-
183
-
-
33744945301
-
Encapsulation of BSA using a modified W/O/O emulsion solvent removal method
-
Ciombor DM, Jaklenec A, Liu AZ, et al. Encapsulation of BSA using a modified W/O/O emulsion solvent removal method. J Microencapsul 2006;23(2):183-94
-
(2006)
J Microencapsul
, vol.23
, Issue.2
, pp. 183-194
-
-
Ciombor, D.M.1
Jaklenec, A.2
Liu, A.Z.3
-
184
-
-
0035153927
-
Emulsion spray-drying for the preparation of albumin-loaded PLGA microspheres
-
Giunchedi P, Conti B, Genta I, et al. Emulsion spray-drying for the preparation of albumin-loaded PLGA microspheres. Drug Dev Ind Pharm 2001;27(7):745-50
-
(2001)
Drug Dev Ind Pharm
, vol.27
, Issue.7
, pp. 745-750
-
-
Giunchedi, P.1
Conti, B.2
Genta, I.3
-
185
-
-
11844260006
-
How cyclodextrin incorporation affects the properties of protein-loaded PLGA-based microspheres: The case of insulin/ hydroxypropyl-beta-cyclodextrin system
-
De Rosa G, Larobina D, Immacolata La Rotonda M, et al. How cyclodextrin incorporation affects the properties of protein-loaded PLGA-based microspheres: the case of insulin/ hydroxypropyl-beta-cyclodextrin system. J Control Release 2005;102(1):71-83
-
(2005)
J Control Release
, vol.102
, Issue.1
, pp. 71-83
-
-
De Rosa, G.1
Larobina, D.2
Immacolata La Rotonda, M.3
-
186
-
-
0034601108
-
Sustained release of recombinant human insulin-like growth factor-I for treatment of diabetes
-
Lam XM, Duenas ET, Daugherty AL, et al. Sustained release of recombinant human insulin-like growth factor-I for treatment of diabetes. J Control Release 2000;67(2-3):281-92
-
(2000)
J Control Release
, vol.67
, Issue.2-3
, pp. 281-292
-
-
Lam, X.M.1
Duenas, E.T.2
Daugherty, A.L.3
-
187
-
-
0035858370
-
Development of poly-(D,L-lactide-coglycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis
-
Cleland JL, Duenas ET, Park A, et al. Development of poly-(D,L-lactide-coglycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis. J Control Release 2001;72(1-3):13-24
-
(2001)
J Control Release
, vol.72
, Issue.1-3
, pp. 13-24
-
-
Cleland, J.L.1
Duenas, E.T.2
Park, A.3
-
188
-
-
0034837639
-
Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres
-
Lam XM, Duenas ET, Cleland JL. Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres. J Pharm Sci 2001;90(9):1356-65
-
(2001)
J Pharm Sci
, vol.90
, Issue.9
, pp. 1356-1365
-
-
Lam, X.M.1
Duenas, E.T.2
Cleland, J.L.3
-
189
-
-
0037449483
-
Feeding liquid, non-ionic surfactant and cyclodextrin affect the properties of insulin-loaded poly(lactide-co-glycolide) microspheres prepared by spray-drying
-
Quaglia F, De Rosa G, Granata E, et al. Feeding liquid, non-ionic surfactant and cyclodextrin affect the properties of insulin-loaded poly(lactide-co-glycolide) microspheres prepared by spray-drying. J Control Release 2003;86(2-3):267-78
-
(2003)
J Control Release
, vol.86
, Issue.2-3
, pp. 267-278
-
-
Quaglia, F.1
De Rosa, G.2
Granata, E.3
-
190
-
-
33646380352
-
Reservoir-Type microcapsules prepared by the solvent exchange method: Effect of formulation parameters on microencapsulation of lysozyme
-
Park JH, Ye M, Yeo Y, et al. Reservoir-Type microcapsules prepared by the solvent exchange method: effect of formulation parameters on microencapsulation of lysozyme. Mol Pharm 2006;3(2):135-43
-
(2006)
Mol Pharm
, vol.3
, Issue.2
, pp. 135-143
-
-
Park, J.H.1
Ye, M.2
Yeo, Y.3
-
191
-
-
0042357195
-
Ultrasonic atomization and subsequent polymer desolvation for peptide and protein microencapsulation into biodegradable polyesters
-
Felder Ch B, Blanco-Prieto MJ, Heizmann J, et al. Ultrasonic atomization and subsequent polymer desolvation for peptide and protein microencapsulation into biodegradable polyesters. J Microencapsul 2003;20(5):553-67
-
(2003)
J Microencapsul
, vol.20
, Issue.5
, pp. 553-567
-
-
Felder Ch, B.1
Blanco-Prieto, M.J.2
Heizmann, J.3
-
192
-
-
26444617169
-
Flow-Through ultrasonic emulsification combined with static micromixing for aseptic production of microspheres by solvent extraction
-
Freitas S, Rudolf B, Merkle HP, Gander B. Flow-Through ultrasonic emulsification combined with static micromixing for aseptic production of microspheres by solvent extraction. Eur J Pharm Biopharm 2005;61(3):181-7
-
(2005)
Eur J Pharm Biopharm
, vol.61
, Issue.3
, pp. 181-187
-
-
Freitas, S.1
Rudolf, B.2
Merkle, H.P.3
Gander, B.4
-
193
-
-
72149125853
-
Sustained release hGH microsphere formulation produced by a novel supercritical fluid technology: In vivo studies
-
Jordan F, Naylor A, Kelly CA, et al. Sustained release hGH microsphere formulation produced by a novel supercritical fluid technology: in vivo studies. J Control Release 2010;141(2):153-60
-
(2010)
J Control Release
, vol.141
, Issue.2
, pp. 153-160
-
-
Jordan, F.1
Naylor, A.2
Kelly, C.A.3
-
194
-
-
33746404654
-
Electrospray encapsulation of water-soluble protein with polylactide. Effects of formulations on morphology, encapsulation efficiency and release profile of particles
-
Xu Y, Hanna MA. Electrospray encapsulation of water-soluble protein with polylactide. Effects of formulations on morphology, encapsulation efficiency and release profile of particles. Int J Pharm 2006;320(1-2):30-6
-
(2006)
Int J Pharm
, vol.320
, Issue.1-2
, pp. 30-36
-
-
Xu, Y.1
Hanna, M.A.2
-
195
-
-
34547592146
-
Encapsulation of proteins in biodegradable polymeric microparticles using electrospray in the Taylor cone-jet mode
-
Xie J, Wang CH. Encapsulation of proteins in biodegradable polymeric microparticles using electrospray in the Taylor cone-jet mode. Biotechnol Bioeng 2007;97(5):1278-90
-
(2007)
Biotechnol Bioeng
, vol.97
, Issue.5
, pp. 1278-1290
-
-
Xie, J.1
Wang, C.H.2
-
196
-
-
33646164433
-
Biodegradable polymeric microspheres with open/closed pores for sustained release of human growth hormone
-
Kim HK, Chung HJ, Park TG. Biodegradable polymeric microspheres with open/closed pores for sustained release of human growth hormone. J Control Release 2006;112(2):167-74
-
(2006)
J Control Release
, vol.112
, Issue.2
, pp. 167-174
-
-
Kim, H.K.1
Chung, H.J.2
Park, T.G.3
-
197
-
-
0037032410
-
Preservation of lysozyme structure and function upon encapsulation and release from poly(lactic-co-glycolic) acid microspheres prepared by the water-inoil-in-water method
-
Perez C, De Jesus P, Griebenow K. Preservation of lysozyme structure and function upon encapsulation and release from poly(lactic-co-glycolic) acid microspheres prepared by the water-inoil-in-water method. Int J Pharm 2002;248(1-2):193-206
-
(2002)
Int J Pharm
, vol.248
, Issue.1-2
, pp. 193-206
-
-
Perez, C.1
De Jesus, P.2
Griebenow, K.3
|