Sustained release of human growth hormone from PLGA solution depots

Pharmaceutical Research

Volumn 16, Issue 12, 1999, Pages 1825-1829

  Brodbeck, Kevin J ^a   Pushpala, Shamim ^a,b   McHugh, Anthony J ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b ALZA CORPORATION   (United States)

Author keywords

Human growth hormone; Phase inversion; Sustained release depot

Indexed keywords

HUMAN GROWTH HORMONE; POLYGLACTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BIODEGRADATION; DIFFUSION; DRUG ABSORPTION; DRUG DEGRADATION; DRUG FORMULATION; HORMONE RELEASE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; RAT; SUSTAINED RELEASE PREPARATION;

EID: 0033403807     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018943107688     Document Type: Article

References (23)

1. J. L. Cleland and A. J. S. Jones. Stable formulations of recombinant human growth hormone and interferon for microencapsulation in biodegradable microspheres. Pharm. Res. 13:1464-1475 (1996).
2. M. L. Radomsky. G. Brouwer, B. J. Floy, D. J. Loury, F. Chu, A. J. Tipton, and L. M. Sanders. The controlled release of ganirelix from the atrigel™ injectable implant system. Proceed. Intern. Symp. Cemtrol. Rel. Bioact. Mater. 20:458-459 (1993).
3. D. L. Johnson, W. Jaworowicz, J. L. Cleland, L. Bailey, M. Charnis, E. Duenas, C. Wu, D. Shepard, S. Magil, T. Last, A. J. S. Jones, and S. D. Putney. The stabilizalion and encapsulation of human growth hormone into biodegradable microspheres. Pharm. Res. 14:730-735 (1997).
4. H. Okada, T. Heya, Y. Igari, M. Yamamoto, Y. Ogawa, H. Toguchi, and T. Shimamoto. One-month-releasing Injectable Microspheres of a Superactive Agonist of LHRH, Leuprolide Acetate. In D. Marshak and D. Liu (eds.), Therapeutic Peptides and Proteins: Formulation, Delivery, and Targeting, Cold Spring Harbor Laboratory Pub., New York, 1989. pp. 107-111.
5. J.C. Gautier, J. L. Grangier, A. Barbier, P. Dupont, D. Dussossoy, G. Pastor, and P. Couvreur. Biodegradable nanoparticles for subcutaneous administration of growth hormone releasing factor (hGRF). J. Contr. Rel. 20:67-78 (1992).
6. F. G. Hutchinson and B. J. A. Furr. Biodegradable polymer systems for the sustained release of polypeptides. J. Contr. Rel. 13:279-294 (1990).
7. T. R. Tice, R. M. Gilley, D. F. Love, F. Labrie, and D. W. Mason. 3-month and 6-month delivery of peptides (LHRH) from injectable, poly (lactide-co-glycolide) microspheres. Proceed. Intern. Symp. Control. Rel. Bioact. Mater 18:467-468 (1991).
8. Y. Yamagata, K. Iga, and H. Okada. Sustained releasable parenteral pharmaceutical preparations and method for producing the same. US Patent No. 5,750,100. (1998).
9. O. F. Johnson, M. M. Ganmukhi, H. Berstein, H. Auer, and M. A. Khan. Composition for sustained release of human growth hormone. US Patent No. 5,891,478. (1999).
10. R. L. Dunn, J. P. English, D. R. Cowsar, and D. P. Vanderbilt. Biodegradable in-situ forming implants and methods of producing the same. US Patent 5,733,950. (1998).
11. L. Yilmaz and A. J. McHugh. Analysis of nonsolvent-solvent-polymer phase diagrams and their relevance to membrane formation. J. Appl. Polym. Sci. 31:997-1018 (1986).
12. S. Tsay and A. J. McHugh. Mass transfer modeling of asymmetric membrane formation in phase inversion. J. Polym. Sci. Polym. Phys. 28:1327-1365 (1990).
13. B. F. Barton, J. L. Reeve, and A. J. McHugh. Observations on the dynamics of nonsolvent-induced phase inversion. J. Polym. Sci. Polym. Phys. 35:569-585 (1997).
14. P. D. Graham, K. J. Brodbeck, and A. J. McHugh. Phase inversion dynamics of PLGA solutions related to drug delivery. J. Contr. Rel. 58:233-245 (1999).
15. K.J. Brodbeck, J. R. DesNoyer, and A. J. McHugh. Phase inversion dynamics of PLGA solutions related to drug delivery - Part II. The role of solution thermodynamics and bath-side mass transfer. J. Contr. Rel., 62:333-344 (1999).
16. E. A. Permyakov, V. L. Shnyrov, L. P. Kalinichenko, A. Kuchar, I. L. Reyzer, and L. J. Berliner. Binding of Zn(II) ions to α-lactalbumin. J. Protein Chem. 10:557-584 (1991).
17. B. C. Cunningham, S. Bass, G. Fuh, and J. A. Wells. Zinc mediation of the binding of human growth hormone to the human prolactin receptor. Science 250:1709-1712 (1990).
18. C. L. Stevenson and M. J. Hageman. Characterization of spray-dried and lyophilized suspensions of zinc-bovine somatotropin salts. Pharm. Res. 11;S-148 (1994).
19. C. L. Stevenson and M. J. Hageman. Diafiltration of aqueous zinc-bovine somatotropin suspensions to remove excess zinc. Pharm. Res. 11;S-148 (1994).
20. B.C. Cunningham, M. G. Mulerrin, and J. A. Wells. Dimerization of human growth hormone by zinc. Science 253:545-548 (1991).
21. 2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro. Biochemistry 36:173-180 (1997).
22. W. A. Ritschel. Handbook of Basic Pharmacokinetics. Fourth Edition. Drug Intelligence Pub., Hamilton, Illinois, 1992, pp. 291-304.
23. M. Ash. Pharmaceutical Additives Electronic Handbook, Synapse Information Resources, Inc., Gower Publishing, Brookfield, Vermont, 1996.