Protein release from poly(lactide-co-glycolide) implants prepared by hot-melt extrusion: Thioester formation as a reason for incomplete release

International Journal of Pharmaceutics

Volumn 438, Issue 1-2, 2012, Pages 302-306

  Ghalanbor, Zahra ^a   Körber, Martin ^a   Bodmeier, Roland ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Biodegradable implant; Hot melt extrusion; Incomplete release; Poly(lactide co glycolide); Protein formulation

Indexed keywords

OLIGOMER; POLYGLACTIN; RESOMER; THIOESTER;

ACYLATION; ARTICLE; BIODEGRADABLE IMPLANT; COVALENT BOND; POROSITY; PRIORITY JOURNAL; PROTEIN SECRETION; SYRINGE;

CYSTEINE; DRUG IMPLANTS; ESTERS; HOT TEMPERATURE; LACTIC ACID; POLYGLYCOLIC ACID; SERUM ALBUMIN, BOVINE;

EID: 84867395808     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.09.015     Document Type: Article

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