Instability of bovine insulin in poly(lactide-co-glycolide) (PLGA) microspheres

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 1, 1996, Pages 235-236

  Uchida, Takahiro ^a   Yagi, Akira ^a   Oda, Yuko ^a   Nakada, Yoichi ^a   Goto, Shigeru ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

bovine insulin; degradation; poly(lactide co glicolide); protein delivery

Indexed keywords

ALUMINUM DERIVATIVE; BOVINE INSULIN; MICROSPHERE; POLYGLACTIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DISPERSION; DRUG DEGRADATION; DRUG RELEASE; DRUG STABILITY; EMULSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCANNING ELECTRON MICROSCOPY; STEARATE ALUMINUM;

EID: 0030039264     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.235     Document Type: Article

References (7)

1. Bodmeier R., McGinity J. M., Int J. Pharm., 43, 179 (1988).
2. Ogawa Y., Yamamoto M., Takada S., Okada H., Shimamoto T., Chem. Pharm. Bull., 36, 1095 (1988).
3. Uchida T., Martin S., Foster T. P., Wardley R. C , Grimm S., Pharm. Res., 11, 1009 (1994).
4. Makino K., Ohshima H., Kondo T., J. Microencapsulation, 3, 195 (1986).
5. Brange J , Langkjaer L., Havelund S., Pharm. Res., 9, 715 (1992).
6. Goto S., Kawata M., Nakamura M., Nagatsuma Y., Fujinaga K., Aoyama T., J. Microencapsulation, 5, 343 (1988).
7. Uchida T., Yagi A., Oda Y., Goto S., J. Microencapsulation, 11, in press, (1996).