Role of solvation effects in protein denaturation: From thermodynamics to single molecules and back

Annual Review of Physical Chemistry

Volumn 62, Issue , 2011, Pages 257-277

  England, Jeremy L ^a   Haran, Gilad ^b  

^a PRINCETON UNIVERSITY   (United States)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

FRET; guanidinium chloride; hydrophobic effect; molecular dynamics simulations; protein folding; single molecule spectroscopy; urea

Indexed keywords

CHEMICAL STABILITY; CHLORINE COMPOUNDS; DENATURATION; FORSTER RESONANCE ENERGY TRANSFER; HYDROPHOBICITY; METABOLISM; MOLECULES; PROTEIN FOLDING; SOLVATION; THERMODYNAMICS; UREA;

COIL-GLOBULE TRANSITIONS; DYNAMICS SIMULATION; GUANIDINIUM CHLORIDES; HYDROPHOBIC EFFECT; MOLECULAR DYNAMIC SIMULATION; PROTEIN DENATURATION; PROTEIN FOLDINGS; SINGLE MOLECULE; SINGLE-MOLECULE SPECTROSCOPY; SOLVATION EFFECT;

MOLECULAR DYNAMICS;

GUANIDINE; PROTEIN; SOLVENT; UREA; WATER;

CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECT; FLUORESCENCE RESONANCE ENERGY TRANSFER; METHODOLOGY; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; REVIEW; THERMODYNAMICS;

FLUORESCENCE RESONANCE ENERGY TRANSFER; GUANIDINE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEINS; SOLVENTS; THERMODYNAMICS; UREA; WATER;

EID: 79953759344     PISSN: 0066426X     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev-physchem-032210-103531     Document Type: Article

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