Recombinant human erythropoietin (rhEPO) loaded poly(lactide-co- glycolide) microspheres: Influence of the encapsulation technique and polymer purity on microsphere characteristics

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 45, Issue 3, 1998, Pages 295-305

  Bittner, Beate ^a   Morlock, Michael ^a   Koll, Hans ^b   Winter, Gerhard ^b   Kissel, Thomas ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Erythropoietin; Microencapsulation techniques; Parenteral protein delivery; Poly(lactide co glycolide)

Indexed keywords

MICROSPHERE; POLYGLACTIN; RECOMBINANT ERYTHROPOIETIN;

ARTICLE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; INTERMETHOD COMPARISON; MICROENCAPSULATION; PROTEIN POLYMERIZATION; PROTEIN PROCESSING; TECHNIQUE;

CALORIMETRY, DIFFERENTIAL SCANNING; DEXTRANS; DRUG COMPOUNDING; DRUG STABILITY; ERYTHROPOIETIN, RECOMBINANT; FLUORESCEIN-5-ISOTHIOCYANATE; HUMANS; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; MOLECULAR WEIGHT; POLYGLYCOLIC ACID; POLYMERS; SOLVENTS;

EID: 0032078388     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(98)00012-5     Document Type: Article

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