Injectable controlled release formulations incorporating protein crystals

Journal of Controlled Release

Volumn 96, Issue 1, 2004, Pages 149-158

  Pechenov, Sergey ^a   Shenoy, Bhami ^a   Yang, Mark X ^a   Basu, Sujit K ^a   Margolin, Alexey L ^a  

^a Altus Pharmaceuticals Inc   (United States)

Author keywords

Controlled release; Crystal morphology; Protein crystals; Protein loading; Stability

Indexed keywords

ACETONITRILE; DRYING; MORPHOLOGY; ORGANIC SOLVENTS; POLYMERIZATION; PROTEINS; SUGAR (SUCROSE);

CONTROLLED RELEASE GEL SYSTEMS; WATER INTERFACES;

CONTROLLED DRUG DELIVERY;

ACETONITRILE; ALCOHOL; AMYLASE; ORGANIC SOLVENT; POLYGLACTIN; SUCROSE ACETATE ISOBUTYRATE; WATER;

AMYLASE RELEASE; ARTICLE; ASPERGILLUS ORYZAE; CONTROLLED RELEASE FORMULATION; CRYSTALLIZATION; DESICCATION; DRUG FORMULATION; DRUG RELEASE; ENZYME ACTIVITY; ENZYME KINETICS; GEL; MORPHOLOGICAL TRAIT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STABILITY;

AMYLASES; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYSTALLIZATION; DELAYED-ACTION PREPARATIONS; GELS; INJECTIONS;

EID: 1842473797     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2004.01.019     Document Type: Article

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