-
1
-
-
30344445931
-
Inflammatory bowel disease: Epidemiology, pathogenesis, and therapeutic opportunities
-
Hanauer SB. Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities. Inflamm Bowel Dis 2006; 12: S3-S9.
-
(2006)
Inflamm Bowel Dis
, vol.12
-
-
Hanauer, S.B.1
-
2
-
-
84862009661
-
Metabolome and inflammasome in inflammatory bowel disease
-
Nanau RN, Neuman MG. Metabolome and inflammasome in inflammatory bowel disease. Transl Res 2012; 160: 1-28.
-
(2012)
Transl Res
, vol.160
, pp. 1-28
-
-
Nanau, R.N.1
Neuman, M.G.2
-
3
-
-
79551526537
-
Role of different inflammatory and tumor biomarkers in the development of ulcerative colitis-associated carcinogenesis
-
Talero E, Sánchez-Fidalgo S, Villega SI, et al. Role of different inflammatory and tumor biomarkers in the development of ulcerative colitis-associated carcinogenesis. Inflamm Bowel Dis 2011; 17: 696-710.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 696-710
-
-
Talero, E.1
Sánchez-Fidalgo, S.2
Villega, S.I.3
-
4
-
-
84862873626
-
TNF-a-induced intestinal epithelial cell shedding: Implications for intestinal barrier function
-
Watson AJM, Hughes KR. TNF-a-induced intestinal epithelial cell shedding: implications for intestinal barrier function. Ann N Y Acad Sci 2012; 1258: 1-8 c.
-
(2012)
Ann N Y Acad Sci
, vol.1258
, pp. 1-8
-
-
Watson, A.J.M.1
Hughes, K.R.2
-
5
-
-
77950641148
-
MDP-NOD2 stimulation induces HNP-1 secretion, which contributes to NOD2 antibacterial function
-
Yamamoto-Furusho JK, Barnich N, Hisamatsu T, Podolsky DK. MDP-NOD2 stimulation induces HNP-1 secretion, which contributes to NOD2 antibacterial function. Inflamm Bowel Dis 2010; 16: 736-42.
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 736-742
-
-
Yamamoto-Furusho, J.K.1
Barnich, N.2
Hisamatsu, T.3
Podolsky, D.K.4
-
6
-
-
0036886760
-
The pathogenesis of inflammatory bowel disease: Translational implications for clinicians
-
Abreu MT. The pathogenesis of inflammatory bowel disease: translational implications for clinicians. Curr Gastroenterol Rep 2002; 4: 481-89.
-
(2002)
Curr Gastroenterol Rep
, vol.4
, pp. 481-489
-
-
Abreu, M.T.1
-
7
-
-
0037029649
-
The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease
-
Neurath MF, Weigmann B, Finotto S, et al. The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease. J Exp Med 2002; 195: 1129-43.
-
(2002)
J Exp Med
, vol.195
, pp. 1129-1143
-
-
Neurath, M.F.1
Weigmann, B.2
Finotto, S.3
-
9
-
-
33748096092
-
Molecular biology of dysplasia and cancer in inflammatory bowel disease
-
Itzkowitz SH. Molecular biology of dysplasia and cancer in inflammatory bowel disease. Gastroenterol Clin North Am 2006; 35: 553-71.
-
(2006)
Gastroenterol Clin North Am
, vol.35
, pp. 553-571
-
-
Itzkowitz, S.H.1
-
10
-
-
33845981059
-
Immunomodulatory effects of (n-3) fatty acids: Putative link to inflammation and colon cancer
-
Chapkin RS, Davidson LA, Ly L, et al. Immunomodulatory effects of (n-3) fatty acids: putative link to inflammation and colon cancer. J Nutr 2007; 137: 200S-204S.
-
(2007)
J Nutr
, vol.137
-
-
Chapkin, R.S.1
Davidson, L.A.2
Ly, L.3
-
11
-
-
77954422428
-
Interferon-gamma-expressing cells are a major source of interleukin-21 in inflammatory bowel diseases
-
Sarra M, Monteleone I, Stolfi C, et al. Interferon-gamma-expressing cells are a major source of interleukin-21 in inflammatory bowel diseases. Inflamm Bowel Dis 2010; 16: 1332-39.
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 1332-1339
-
-
Sarra, M.1
Monteleone, I.2
Stolfi, C.3
-
12
-
-
79955563439
-
Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases
-
Strober W, Fuss IJ. Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases. Gastroenterology 2011; 140: 1756-67.
-
(2011)
Gastroenterology
, vol.140
, pp. 1756-1767
-
-
Strober, W.1
Fuss, I.J.2
-
13
-
-
78650430453
-
Crohn disease: A current perspective on genetics, autophagy and immunity
-
Stappenbeck TS, Rioux JD, Mizoguchi A, et al. Crohn disease: A current perspective on genetics, autophagy and immunity. Auto-phagy 2011; 7: 355-74.
-
(2011)
Auto-phagy
, vol.7
, pp. 355-374
-
-
Stappenbeck, T.S.1
Rioux, J.D.2
Mizoguchi, A.3
-
14
-
-
68649126866
-
Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals
-
Martin B, Hirota K, Cua DJ, et al. Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. Immunity 2009; 31: 321-30.
-
(2009)
Immunity
, vol.31
, pp. 321-330
-
-
Martin, B.1
Hirota, K.2
Cua, D.J.3
-
15
-
-
84876348441
-
The role of pattern recognition receptors in intestinal inflammation
-
Fukata M, Arditi M. The role of pattern recognition receptors in intestinal inflammation. Mucosal Immunol 2013; 6: 451-63.
-
(2013)
Mucosal Immunol
, vol.6
, pp. 451-463
-
-
Fukata, M.1
Arditi, M.2
-
16
-
-
84865294366
-
Nod-like receptors in the control of intestinal inflammation
-
Rubino SJ, Selvanantham T, Girardin SE, et al. Nod-like receptors in the control of intestinal inflammation. Curr Opin Immunol. 2012; 24: 398-404.
-
(2012)
Curr Opin Immunol
, vol.24
, pp. 398-404
-
-
Rubino, S.J.1
Selvanantham, T.2
Girardin, S.E.3
-
17
-
-
80054975975
-
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
-
Rivas MA, Beaudoin M, Gardet A, et al. Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease. Nat Genet 2011; 43: 1066-73.
-
(2011)
Nat Genet
, vol.43
, pp. 1066-1073
-
-
Rivas, M.A.1
Beaudoin, M.2
Gardet, A.3
-
18
-
-
34548425563
-
Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy
-
Van Limbergen J, Nimmo ER, Russell RK, et al. Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy. Hum Mol Genet 2007; 16: 2175-86.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 2175-2186
-
-
van Limbergen, J.1
Nimmo, E.R.2
Russell, R.K.3
-
19
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001; 411: 599-603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
-
20
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DPB, Barrett JC, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nature Genetic 2010; 42: 1118-25.
-
(2010)
Nature Genetic
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.B.2
Barrett, J.C.3
-
21
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos LH, Carneiro LA, Ramjeet M, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 2010; 11: 55-62.
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
-
22
-
-
73849151394
-
NOD2 stimulation induces auto-phagy in dendritic cells influencing bacterial handling and antigen presentation
-
Cooney R, Baker J, Brain O, et al. NOD2 stimulation induces auto-phagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med 2010; 16: 90-97.
-
(2010)
Nat Med
, vol.16
, pp. 90-97
-
-
Cooney, R.1
Baker, J.2
Brain, O.3
-
23
-
-
55749096587
-
Innate immune signalling at intestinal mucosal surfaces: A fine line between host protection and destruction
-
Cario E. Innate immune signalling at intestinal mucosal surfaces: a fine line between host protection and destruction. Curr Opin Gas-troenterol 2008; 24: 725-32.
-
(2008)
Curr Opin Gas-troenterol
, vol.24
, pp. 725-732
-
-
Cario, E.1
-
24
-
-
79956118584
-
Autophagy signaling through reactive oxygen species
-
Huang J, Lam GY, Brumell JH. Autophagy signaling through reactive oxygen species. Antioxid Redox Signal 2011; 14: 2215-31.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 2215-2231
-
-
Huang, J.1
Lam, G.Y.2
Brumell, J.H.3
-
25
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Gen 2007; 39: 207-211.
-
(2007)
Nat Gen
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
-
26
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Gen 2007; 39: 596-604.
-
(2007)
Nat Gen
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
-
27
-
-
33745151999
-
Cellular and molecular immunopatho-genesis of ulcerative colitis
-
Zhang S, Zhao X, Zhang D. Cellular and molecular immunopatho-genesis of ulcerative colitis. Cell Mol Immunol 2006; 3: 35-40.
-
(2006)
Cell Mol Immunol
, vol.3
, pp. 35-40
-
-
Zhang, S.1
Zhao, X.2
Zhang, D.3
-
28
-
-
84880682970
-
Humoral pattern-recognition and the complement system
-
doi: 10.1111/sji.12070, [Epub ahead of print]
-
Degn SE, Thiel S. Humoral pattern-recognition and the complement system. Scand J Immunol. 2013. doi: 10.1111/sji.12070, [Epub ahead of print].
-
(2013)
Scand J Immunol
-
-
Degn, S.E.1
Thiel, S.2
-
29
-
-
33645068615
-
Intestinal epithelial cell signalling and host- derived negative regulators under chronic inflammation: To be or not to be activated determines the balance towards commensal bacteria
-
Haller D. Intestinal epithelial cell signalling and host- derived negative regulators under chronic inflammation: to be or not to be activated determines the balance towards commensal bacteria. Neuro-gastroenterol Motil 2006; 18: 184-199.
-
(2006)
Neuro-gastroenterol Motil
, vol.18
, pp. 184-199
-
-
Haller, D.1
-
30
-
-
23844521000
-
Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists
-
Fritz JH, Girardin SE, Fitting C, et al. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. Europ J Immunol 2005; 35: 2459-70.
-
(2005)
Europ J Immunol
, vol.35
, pp. 2459-2470
-
-
Fritz, J.H.1
Girardin, S.E.2
Fitting, C.3
-
31
-
-
0038109983
-
Crohn's disease and the NOD2 gene: A role for paneth cells
-
Lala S, Ogura Y, Osborne C, et al. Crohn's disease and the NOD2 gene: a role for paneth cells. Gastroenterology 2003; 125: 47-57.
-
(2003)
Gastroenterology
, vol.125
, pp. 47-57
-
-
Lala, S.1
Ogura, Y.2
Osborne, C.3
-
32
-
-
71649089949
-
Role of NF-kappaB activation in intestinal immune homeostasis
-
Wullaert A. Role of NF-kappaB activation in intestinal immune homeostasis. International J Med Microbiol 2010; 300: 49-56.
-
(2010)
International J Med Microbiol
, vol.300
, pp. 49-56
-
-
Wullaert, A.1
-
33
-
-
34848928674
-
CARD15/NOD2 is required for Peyer's patches homeostasis in mice
-
Barreau F, Meinzer U, Chareyre F, et al. CARD15/NOD2 is required for Peyer's patches homeostasis in mice. PLoS ONE 2007; 2: e523.
-
(2007)
PLoS ONE
, vol.2
-
-
Barreau, F.1
Meinzer, U.2
Chareyre, F.3
-
34
-
-
38849163741
-
Muramyl dipeptide activation of nucleotide- binding oligomerization domain 2 protects mice from experimental colitis
-
Watanabe T, Asano N, Murray PJ, et al. Muramyl dipeptide activation of nucleotide- binding oligomerization domain 2 protects mice from experimental colitis. J Clin Invest 2008; 118: 545-59.
-
(2008)
J Clin Invest
, vol.118
, pp. 545-559
-
-
Watanabe, T.1
Asano, N.2
Murray, P.J.3
-
35
-
-
33748493563
-
Nucleotide binding oli-gomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis
-
Watanabe T, Kitani A, Murray PJ, et al. Nucleotide binding oli-gomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis. Immunity 2006; 25: 473-85.
-
(2006)
Immunity
, vol.25
, pp. 473-485
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
-
36
-
-
39749084641
-
Active caspase-1 is a regulator of unconventional protein secretion
-
Keller M, Rüegg A, Werner S, Beer H-D: Active caspase-1 is a regulator of unconventional protein secretion. Cell 2008; 132: 818-31.
-
(2008)
Cell
, vol.132
, pp. 818-831
-
-
Keller, M.1
Rüegg, A.2
Werner, S.3
Beer, H.-D.4
-
37
-
-
77952303410
-
The NLRP3 in-flammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
-
Allen IC, TeKippe EM, Woodford RMT, et al. The NLRP3 in-flammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med 2010; 207: 1045-56.
-
(2010)
J Exp Med
, vol.207
, pp. 1045-1056
-
-
Allen, I.C.1
Tekippe, E.M.2
Woodford, R.M.T.3
-
38
-
-
77950002937
-
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
-
Zaki MH, Boyd KL, Vogel P, et al. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 2010; 32: 379-91.
-
(2010)
Immunity
, vol.32
, pp. 379-391
-
-
Zaki, M.H.1
Boyd, K.L.2
Vogel, P.3
-
39
-
-
79955846705
-
NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
-
Hirota SA, Ng J, Lueng A, et al. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflamm Bowel Dis 2011; 17: 1359-72.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1359-1372
-
-
Hirota, S.A.1
Ng, J.2
Lueng, A.3
-
40
-
-
33745775434
-
Mechanisms of disease: Pathogenesis of Crohn's disease and ulcerative colitis
-
Sartor RB. Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. Nat Clin Pract Gastroenterol Hepatol 2006; 3: 390-407.
-
(2006)
Nat Clin Pract Gastroenterol Hepatol
, vol.3
, pp. 390-407
-
-
Sartor, R.B.1
-
41
-
-
0036828844
-
Induction of Nod2 in mye-lomonocytic and intestinal epithelial cells via nuclear factor-kappa B activation
-
Gutierrez O, Pipaon C, Inohara N, et al. Induction of Nod2 in mye-lomonocytic and intestinal epithelial cells via nuclear factor-kappa B activation. J Biol Chem 2002; 277: 41701-05.
-
(2002)
J Biol Chem
, vol.277
, pp. 41701-41705
-
-
Gutierrez, O.1
Pipaon, C.2
Inohara, N.3
-
42
-
-
70350513270
-
Regulation of tissue homeostasis by NF-kappaB signalling: Implications for inflammatory diseases. Regulation of tissue homeostasis by NF-kappaB signalling: Implications for inflammatory diseases
-
Pasparakis M. Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases. Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases. Nature Reviews Immunol 2009; 9: 778-88.
-
(2009)
Nature Reviews Immunol
, vol.9
, pp. 778-788
-
-
Pasparakis, M.1
-
43
-
-
33745342580
-
NFkappaB pathway: A good signalling paradigm and therapeutic target
-
Tergaonkar V. NFkappaB pathway: a good signalling paradigm and therapeutic target. Int J Biochem Cell Biol 2006; 38: 1647-53.
-
(2006)
Int J Biochem Cell Biol
, vol.38
, pp. 1647-1653
-
-
Tergaonkar, V.1
-
44
-
-
70350764831
-
NF-kappaB signalling pathway, inflammation and colorectal cancer
-
Wang S, Liu Z, Wang L, et al. NF-kappaB signalling pathway, inflammation and colorectal cancer. Cell Mol Immunol 2009; 6: 327-34.
-
(2009)
Cell Mol Immunol
, vol.6
, pp. 327-334
-
-
Wang, S.1
Liu, Z.2
Wang, L.3
-
45
-
-
27644543662
-
Proinflammatory cytokines and signalling pathways in intestinal innate immune cells
-
In: Mestecky J, et al. Eds, Philadelphia, Elsevier
-
Sartor RB, Hoentjen F. Proinflammatory cytokines and signalling pathways in intestinal innate immune cells. In: Mestecky J, et al. Eds, Mucosal Immunology. Philadelphia, Elsevier 2005; p681-701.
-
(2005)
Mucosal Immunology
-
-
Sartor, R.B.1
Hoentjen, F.2
-
46
-
-
77955251736
-
Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components
-
Martin H. Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components. Mutat Res. 2010; 690: 57-63.
-
(2010)
Mutat Res
, vol.690
, pp. 57-63
-
-
Martin, H.1
-
47
-
-
77953248869
-
The role of T cell PPAR gamma in mice with experimental inflammatory bowel disease
-
Guri AJ, Mohapatra SK, Horne WT et al. The role of T cell PPAR gamma in mice with experimental inflammatory bowel disease. BMC Gastroenterol 2010; 10: 60.
-
(2010)
BMC Gastroenterol
, vol.10
, pp. 60
-
-
Guri, A.J.1
Mohapatra, S.K.2
Horne, W.T.3
-
48
-
-
33744937585
-
CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD
-
Bassaganya-riera J, Hontecillas R. CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD. Clin Nutr 2006; 25: 454-65.
-
(2006)
Clin Nutr
, vol.25
, pp. 454-465
-
-
Bassaganya-Riera, J.1
Hontecillas, R.2
-
49
-
-
4444280899
-
Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease
-
Bassaganya-riera J, Reynolds K, Martino-catt S, et al. Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease. Gastroen-terology 2004; 127: 777-91.
-
(2004)
Gastroen-terology
, vol.127
, pp. 777-791
-
-
Bassaganya-Riera, J.1
Reynolds, K.2
Martino-Catt, S.3
-
50
-
-
39749114544
-
Rosiglitazone for active ulcerative colitis: A randomized placebo-controlled trial
-
Lewis JD, Lichtenstein GR, Deren JJ, et al. Rosiglitazone for active ulcerative colitis: a randomized placebo-controlled trial. Gastroen-terology 2008; 134: 688-95.
-
(2008)
Gastroen-terology
, vol.134
, pp. 688-695
-
-
Lewis, J.D.1
Lichtenstein, G.R.2
Deren, J.J.3
-
51
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 2002; 10: 417-26.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
52
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
Franchi L, Amer A, Body-Malapel M, et al. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol 2006; 7: 576-82.
-
(2006)
Nat Immunol
, vol.7
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
-
53
-
-
33744493091
-
Cytoplasmic flagel-lin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao EA, Alpuche-Aranda CM, Dors M, et al. Cytoplasmic flagel-lin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol 2006; 7: 569-75.
-
(2006)
Nat Immunol
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
-
54
-
-
42749096082
-
Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP
-
Zhernakova A, Festen EM, Franke L, et al. Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP. Am J Hum Gen 2008; 82: 1202-10.
-
(2008)
Am J Hum Gen
, vol.82
, pp. 1202-1210
-
-
Zhernakova, A.1
Festen, E.M.2
Franke, L.3
-
55
-
-
81855228056
-
Inflammasomes in intestinal inflammation and cancer
-
Chen GY, Núñez G. Inflammasomes in intestinal inflammation and cancer. Gastroenterology 2011; 141: 1986-99.
-
(2011)
Gastroenterology
, vol.141
, pp. 1986-1999
-
-
Chen, G.Y.1
Núñez, G.2
-
56
-
-
79957689114
-
ER stress is implicated in mito-chondrial dysfunction-induced apoptosis of pancreatic beta cells
-
Lee JW, Kim WH, Yeo J, et al. ER stress is implicated in mito-chondrial dysfunction-induced apoptosis of pancreatic beta cells. Mol Cells 2010; 30: 545-49.
-
(2010)
Mol Cells
, vol.30
, pp. 545-549
-
-
Lee, J.W.1
Kim, W.H.2
Yeo, J.3
-
58
-
-
79956220325
-
Mitochondrial TRAP1 regulates the unfolded protein response in the endoplasmic reticulum
-
Takemoto K, Miyata S, Takamura H, et al. Mitochondrial TRAP1 regulates the unfolded protein response in the endoplasmic reticulum. Neurochem Int 2011; 58: 880-7.
-
(2011)
Neurochem Int
, vol.58
, pp. 880-887
-
-
Takemoto, K.1
Miyata, S.2
Takamura, H.3
-
59
-
-
77954144700
-
Endoplasmic reticulum stress: Implications for inflammatory bowel disease pathogenesis
-
Kaser A, Martínez-Naves E, Blumberg RS. Endoplasmic reticulum stress: implications for inflammatory bowel disease pathogenesis. Curr Opin Gastroenterol 2010; 26: 318-26.
-
(2010)
Curr Opin Gastroenterol
, vol.26
, pp. 318-326
-
-
Kaser, A.1
Martínez-Naves, E.2
Blumberg, R.S.3
-
60
-
-
33745820796
-
Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and en-doplasmic reticulum stress
-
Back SH, Lee K, Vink E, et al. Cytoplasmic IRE1alpha-mediated XBP1 mRNA splicing in the absence of nuclear processing and en-doplasmic reticulum stress. J Biol Chem 2006; 281: 18691-706.
-
(2006)
J Biol Chem
, vol.281
, pp. 18691-18706
-
-
Back, S.H.1
Lee, K.2
Vink, E.3
-
61
-
-
84881475553
-
The unfolded protein response and gastrointestinal disease
-
Kaser A, Adolph TE, Blumberg RS. The unfolded protein response and gastrointestinal disease. Semin Immunopathol. 2013; 35: 307-19.
-
(2013)
Semin Immunopathol
, vol.35
, pp. 307-319
-
-
Kaser, A.1
Adolph, T.E.2
Blumberg, R.S.3
-
62
-
-
75749108288
-
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis
-
Nakamura T, Furuhashi M, Li P, et al. Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis. Cell 2010; 140: 338-48.
-
(2010)
Cell
, vol.140
, pp. 338-348
-
-
Nakamura, T.1
Furuhashi, M.2
Li, P.3
-
63
-
-
84874263775
-
Necroptosis: The release of damage-associated molecular patterns and its physiological relevance
-
Kaczmarek A, Vandenabeele P, Krysko DV. Necroptosis: the release of damage-associated molecular patterns and its physiological relevance. Immunity 2013; 38: 209-23.
-
(2013)
Immunity
, vol.38
, pp. 209-223
-
-
Kaczmarek, A.1
Vandenabeele, P.2
Krysko, D.V.3
-
64
-
-
84881030277
-
Complex Roles of Caspases in the Pathogenesis of Inflammatory Bowel Disease
-
doi: 10.1053/ j.gastro.2012.11.035, [Epub ahead of print]
-
Becker C, Watson AJ, Neurath MF. Complex Roles of Caspases in the Pathogenesis of Inflammatory Bowel Disease. Gastroenterology 2012. doi: 10.1053/ j.gastro.2012.11.035, [Epub ahead of print].
-
(2012)
Gastroenterology
-
-
Becker, C.1
Watson, A.J.2
Neurath, M.F.3
-
65
-
-
80053580530
-
RIPK-dependent necrosis and its regulation by caspases: A mystery in five acts
-
Green DR, Oberst A, Dillon CP, et al. RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts. Mol Cell 2011; 44: 9-16.
-
(2011)
Mol Cell
, vol.44
, pp. 9-16
-
-
Green, D.R.1
Oberst, A.2
Dillon, C.P.3
-
66
-
-
77958126597
-
What keeps us awake? The role of clocks and hourglasses, light, and melatonin
-
Cajochen C, Chellappa S, Schmidt C. What keeps us awake? The role of clocks and hourglasses, light, and melatonin. Int Rev Neuro-biol 2010; 93: 57-90.
-
(2010)
Int Rev Neuro-biol
, vol.93
, pp. 57-90
-
-
Cajochen, C.1
Chellappa, S.2
Schmidt, C.3
-
67
-
-
80054821679
-
Distribution, function and physiological role of melatonin in the lower gut
-
Chen CQ, Fichna J, Bashashati M, Li YY, Storr M. Distribution, function and physiological role of melatonin in the lower gut. World J Gastroenterol 2011; 17: 3888-98.
-
(2011)
World J Gastroenterol
, vol.17
, pp. 3888-3898
-
-
Chen, C.Q.1
Fichna, J.2
Bashashati, M.3
Li, Y.Y.4
Storr, M.5
-
68
-
-
3242753505
-
mRNA expression of nuclear receptor RZR/RORalpha, melatonin membrane receptor MT, and hydroxindole-O-methyltransferase in different populations of human immune cells
-
Pozo D, García-Mauriño S, Guerrero JM, Calvo JR. mRNA expression of nuclear receptor RZR/RORalpha, melatonin membrane receptor MT, and hydroxindole-O-methyltransferase in different populations of human immune cells. J Pineal Res 2004; 37: 48-54.
-
(2004)
J Pineal Res
, vol.37
, pp. 48-54
-
-
Pozo, D.1
García-Mauriño, S.2
Guerrero, J.M.3
Calvo, J.R.4
-
69
-
-
33947592217
-
Melatonin and its metabolites: New findings regarding their production and their radical scavenging actions
-
Reiter RJ, Tan DX, Terron MP, Flores LJ, Czarnocki Z. Melatonin and its metabolites: new findings regarding their production and their radical scavenging actions. Acta Biochim Pol 2007; 54: 1-9.
-
(2007)
Acta Biochim Pol
, vol.54
, pp. 1-9
-
-
Reiter, R.J.1
Tan, D.X.2
Terron, M.P.3
Flores, L.J.4
Czarnocki, Z.5
-
70
-
-
34147133767
-
Melatonin in gastropro-tection against stress-induced acute gastric lesions and in healing of chronic gastric ulcers
-
Konturek SJ, Konturek PC, Brzozowski T. Melatonin in gastropro-tection against stress-induced acute gastric lesions and in healing of chronic gastric ulcers. J Physiol Pharmacol 2006; 57(Suppl 5): 51-66.
-
(2006)
J Physiol Pharmacol
, vol.57
, Issue.SUPPL. 5
, pp. 51-66
-
-
Konturek, S.J.1
Konturek, P.C.2
Brzozowski, T.3
-
71
-
-
38149134547
-
Melatonin as modulator of pancreatic enzyme secretion and pancreatoprotector
-
Jaworek J, Nawrot-Porabka K, Leja-Szpak A, et al. Melatonin as modulator of pancreatic enzyme secretion and pancreatoprotector. J Physiol Pharmacol 2007; 58(Suppl 6): 65-80.
-
(2007)
J Physiol Pharmacol
, vol.58
, Issue.SUPPL. 6
, pp. 65-80
-
-
Jaworek, J.1
Nawrot-Porabka, K.2
Leja-Szpak, A.3
-
72
-
-
84861306797
-
Melatonin, a promising supplement in inflammatory bowel disease: A comprehensive review of evidences
-
Mozaffari S, Abdollahi M. Melatonin, a promising supplement in inflammatory bowel disease: a comprehensive review of evidences. Curr Pharm Des 2011; 17: 4372-8.
-
(2011)
Curr Pharm Des
, vol.17
, pp. 4372-4378
-
-
Mozaffari, S.1
Abdollahi, M.2
-
73
-
-
79954536320
-
Implications of melatonin therapy in irritable bowel syndrome: A systematic review
-
Mozaffari S, Rahimi R, Abdollahi M. Implications of melatonin therapy in irritable bowel syndrome: a systematic review. Curr Pharm Des 2010; 16: 3646-55.
-
(2010)
Curr Pharm Des
, vol.16
, pp. 3646-3655
-
-
Mozaffari, S.1
Rahimi, R.2
Abdollahi, M.3
-
74
-
-
57649225896
-
Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats
-
Tanaka T, Yasui Y, Tanaka M, Tanaka T, Oyama T, Rahman KM. Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats. Chem Biol Interact 2009; 177: 128-36.
-
(2009)
Chem Biol Interact
, vol.177
, pp. 128-136
-
-
Tanaka, T.1
Yasui, Y.2
Tanaka, M.3
Tanaka, T.4
Oyama, T.5
Rahman, K.M.6
-
76
-
-
84883260437
-
Circulating CD4+ and CD8+ T cells are activated in IBD and are associated with plasma markers of inflammation
-
doi: 10.1111/imm.12114, [Epub ahead of print]
-
Funderburg NT, Stubblefield Park SR, Sung HC, et al. Circulating CD4+ and CD8+ T cells are activated in IBD and are associated with plasma markers of inflammation. Immunology 2013. doi: 10.1111/imm.12114, [Epub ahead of print].
-
(2013)
Immunology
-
-
Funderburg, N.T.1
Stubblefield Park, S.R.2
Sung, H.C.3
-
77
-
-
84857493989
-
Regulatory dendritic cells pulsed with carbonic anhydrase I protect mice from colitis induced by CD4+CD25- T cells
-
Yamanishi H, Murakami H, Ikeda Y, et al. Regulatory dendritic cells pulsed with carbonic anhydrase I protect mice from colitis induced by CD4+CD25- T cells. J Immunol 2012; 188: 2164-72.
-
(2012)
J Immunol
, vol.188
, pp. 2164-2172
-
-
Yamanishi, H.1
Murakami, H.2
Ikeda, Y.3
-
78
-
-
84877836558
-
Effect of endogen-exogenous melatonin and erythropoietin on dinitrobenzene sulfonic acid-induced colitis
-
Tasdemir S, Parlakpinar H, Vardi N, Kaya E, Acet A. Effect of endogen-exogenous melatonin and erythropoietin on dinitrobenzene sulfonic acid-induced colitis. Fundam Clin Pharmacol 2013; 27: 299-307.
-
(2013)
Fundam Clin Pharmacol
, vol.27
, pp. 299-307
-
-
Tasdemir, S.1
Parlakpinar, H.2
Vardi, N.3
Kaya, E.4
Acet, A.5
-
79
-
-
84866173368
-
Etiology of inflammatory bowel disease: A unified hypothesis
-
Qin X. Etiology of inflammatory bowel disease: a unified hypothesis. World J Gastroenterol 2012; 18: 1708-22.
-
(2012)
World J Gastroenterol
, vol.18
, pp. 1708-1722
-
-
Qin, X.1
-
80
-
-
0036790693
-
Melatonin reduces colon immunological injury in rats by regulating activity of macrophages
-
Mei Q, Yu JP, Xu JM, Wei W, Xiang L, Yue L. Melatonin reduces colon immunological injury in rats by regulating activity of macrophages. Acta Pharmacol Sin 2002; 23: 882-6.
-
(2002)
Acta Pharmacol Sin
, vol.23
, pp. 882-886
-
-
Mei, Q.1
Yu, J.P.2
Xu, J.M.3
Wei, W.4
Xiang, L.5
Yue, L.6
-
81
-
-
84890130576
-
Melatonin Reduces Ulcerative Colitis-Associated Local and Systemic Damage in Mice: Investigation on Possible Mechanisms
-
doi: 10.1007/s10620-013-2831-6, [Epub ahead of print]
-
Trivedi PP, Jena GB. Melatonin Reduces Ulcerative Colitis-Associated Local and Systemic Damage in Mice: Investigation on Possible Mechanisms. Dig Dis Sci. 2013. doi: 10.1007/s10620-013-2831-6, [Epub ahead of print].
-
(2013)
Dig Dis Sci
-
-
Trivedi, P.P.1
Jena, G.B.2
-
82
-
-
49549087478
-
Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis
-
Esposito E, Mazzon E, Riccardi L, Caminiti R, Meli R, Cuzzocrea S. Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis. J Pineal Res 2008; 45: 166-73.
-
(2008)
J Pineal Res
, vol.45
, pp. 166-173
-
-
Esposito, E.1
Mazzon, E.2
Riccardi, L.3
Caminiti, R.4
Meli, R.5
Cuzzocrea, S.6
-
83
-
-
79952446269
-
Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats
-
Tahan G, Gramignoli R, Marongiu F, et al. Melatonin expresses powerful anti-inflammatory and antioxidant activities resulting in complete improvement of acetic-acid-induced colitis in rats. Dig Dis Sci 2011; 56: 715-20.
-
(2011)
Dig Dis Sci
, vol.56
, pp. 715-720
-
-
Tahan, G.1
Gramignoli, R.2
Marongiu, F.3
-
84
-
-
25644449484
-
Melatonin reduces inflammatory injury through inhibiting NF-kappaB activation in rats with colitis
-
Li JH, Yu JP, Yu HG, et al. Melatonin reduces inflammatory injury through inhibiting NF-kappaB activation in rats with colitis. Mediators Inflamm 2005; 2005: 185-93.
-
(2005)
Mediators Inflamm
, vol.2005
, pp. 185-193
-
-
Li, J.H.1
Yu, J.P.2
Yu, H.G.3
-
85
-
-
33749365523
-
Melatonin modulates signal transduction pathways and apoptosis in experimental colitis
-
Mazzon E, Esposito E, Crisafulli C, et al. Melatonin modulates signal transduction pathways and apoptosis in experimental colitis. J Pineal Res 2006; 41: 363-73.
-
(2006)
J Pineal Res
, vol.41
, pp. 363-373
-
-
Mazzon, E.1
Esposito, E.2
Crisafulli, C.3
-
86
-
-
0035191499
-
Melatonin reduces dini-trobenzene sulfonic acid-induced colitis
-
Cuzzocrea S, Mazzon E, Serraino I, et al. Melatonin reduces dini-trobenzene sulfonic acid-induced colitis. J Pineal Res 2001; 30: 1-12.
-
(2001)
J Pineal Res
, vol.30
, pp. 1-12
-
-
Cuzzocrea, S.1
Mazzon, E.2
Serraino, I.3
-
87
-
-
84867867477
-
The nuclear factor kappa B signaling pathway: Integrating metabolism with inflammation
-
Tornatore L, Thotakura AK, Bennett J, Moretti M, Franzoso G. The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation. Trends Cell Biol 2012; 22: 557-66.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 557-566
-
-
Tornatore, L.1
Thotakura, A.K.2
Bennett, J.3
Moretti, M.4
Franzoso, G.5
-
89
-
-
0038389797
-
Effects of melatonin on the expression of iNOS and COX-2 in rat models of colitis
-
Dong WG, Mei Q, Yu JP, Xu JM, Xiang L, Xu Y. Effects of melatonin on the expression of iNOS and COX-2 in rat models of colitis. World J Gastroenterol 2003; 9: 1307-11.
-
(2003)
World J Gastroenterol
, vol.9
, pp. 1307-1311
-
-
Dong, W.G.1
Mei, Q.2
Yu, J.P.3
Xu, J.M.4
Xiang, L.5
Xu, Y.6
-
90
-
-
27144513254
-
Change of nitric oxide in experimental colitis and its inhibition by melatonin in vivo and in vitro
-
Mei Q, Xu JM, Xiang L, Hu YM, Hu XP, Xu ZW. Change of nitric oxide in experimental colitis and its inhibition by melatonin in vivo and in vitro. Postgrad Med J 2005; 81: 667-72.
-
(2005)
Postgrad Med J
, vol.81
, pp. 667-672
-
-
Mei, Q.1
Xu, J.M.2
Xiang, L.3
Hu, Y.M.4
Hu, X.P.5
Xu, Z.W.6
-
91
-
-
82155162448
-
The role of innate immune-stimulated epithelial apoptosis during gastrointestinal inflammatory diseases
-
Siggers RH, Hackam DJ. The role of innate immune-stimulated epithelial apoptosis during gastrointestinal inflammatory diseases. Cell Mol Life Sci 2011; 68: 3623-34.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 3623-3634
-
-
Siggers, R.H.1
Hackam, D.J.2
-
92
-
-
84861435630
-
A perspective on mammalian caspases as positive and negative regulators of inflammation
-
Martin SJ, Henry CM, Cullen SP. A perspective on mammalian caspases as positive and negative regulators of inflammation. Mol Cell 2012; 46: 387-97.
-
(2012)
Mol Cell
, vol.46
, pp. 387-397
-
-
Martin, S.J.1
Henry, C.M.2
Cullen, S.P.3
-
93
-
-
33748695781
-
The effect of melatonin on TNBS-induced colitis
-
Necefli A, Tulumoglu B, Giris M, et al. The effect of melatonin on TNBS-induced colitis. Dig Dis Sci 2006; 51: 1538-45.
-
(2006)
Dig Dis Sci
, vol.51
, pp. 1538-1545
-
-
Necefli, A.1
Tulumoglu, B.2
Giris, M.3
-
94
-
-
40149105410
-
Melatonin reduces bacterial translocation and apoptosis in trinitrobenzene sulphonic acid-induced colitis of rats
-
Akcan A, Kucuk C, Sozuer E, et al. Melatonin reduces bacterial translocation and apoptosis in trinitrobenzene sulphonic acid-induced colitis of rats. World J Gastroenterol 2008; 14: 918-24.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 918-924
-
-
Akcan, A.1
Kucuk, C.2
Sozuer, E.3
-
95
-
-
78149411295
-
Melatonin: Action as antioxidant and potential applications in human disease and aging
-
Bonnefont-Rousselot D, Collin F. Melatonin: action as antioxidant and potential applications in human disease and aging. Toxicology 2010; 278: 55-67.
-
(2010)
Toxicology
, vol.278
, pp. 55-67
-
-
Bonnefont-Rousselot, D.1
Collin, F.2
-
97
-
-
84862004249
-
Oxidative stress and redox signaling mechanisms of inflammatory bowel disease: Updated experimental and clinical evidence
-
Zhu H, Li YR. Oxidative stress and redox signaling mechanisms of inflammatory bowel disease: updated experimental and clinical evidence. Exp Biol Med (Maywood). 2012; 237: 474-80.
-
(2012)
Exp Biol Med (Maywood)
, vol.237
, pp. 474-480
-
-
Zhu, H.1
Li, Y.R.2
-
98
-
-
0029349171
-
Melatonin reduces the severity of dex-tran-induced colitis in mice
-
Pentney PT, Bubenik GA. Melatonin reduces the severity of dex-tran-induced colitis in mice. J Pineal Res 1995; 19: 31-9.
-
(1995)
J Pineal Res
, vol.19
, pp. 31-39
-
-
Pentney, P.T.1
Bubenik, G.A.2
-
99
-
-
0032545762
-
Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation
-
Cuzzocrea S, Zingarelli B, Gilad E, Hake P, Salzman AL, Szabó C. Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation. Eur J Pharmacol 1998; 342: 67-76.
-
(1998)
Eur J Pharmacol
, vol.342
, pp. 67-76
-
-
Cuzzocrea, S.1
Zingarelli, B.2
Gilad, E.3
Hake, P.4
Salzman, A.L.5
Szabó, C.6
-
100
-
-
84874825677
-
Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin
-
Fischer TW, Kleszczyhski K, Hardkop LH, Kruse N, Zillikens D. Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2'-deoxyguanosine) in ex vivo human skin. J Pineal Res 2013; 54: 303-12.
-
(2013)
J Pineal Res
, vol.54
, pp. 303-312
-
-
Fischer, T.W.1
Kleszczyhski, K.2
Hardkop, L.H.3
Kruse, N.4
Zillikens, D.5
-
101
-
-
34147219227
-
Protective effect of melatonin in acetic acid induced colitis in rats
-
Nosál'ová V, Zeman M, Cerná S, Navarová J, Zakálová M. Protective effect of melatonin in acetic acid induced colitis in rats. J Pineal Res 2007; 42: 364-70.
-
(2007)
J Pineal Res
, vol.42
, pp. 364-370
-
-
Nosál'ová, V.1
Zeman, M.2
Cerná, S.3
Navarová, J.4
Zakálová, M.5
-
102
-
-
80355143529
-
Evaluation of melatonin effectiveness in the adjuvant treatment of ulcerative colitis
-
Chojnacki C, Wisniewska-Jarosinska M, Walecka-Kapica E, Klupinska G, Jaworek J, Chojnacki J. Evaluation of melatonin effectiveness in the adjuvant treatment of ulcerative colitis. J Physiol Pharmacol 2011; 62: 327-34.
-
(2011)
J Physiol Pharmacol
, vol.62
, pp. 327-334
-
-
Chojnacki, C.1
Wisniewska-Jarosinska, M.2
Walecka-Kapica, E.3
Klupinska, G.4
Jaworek, J.5
Chojnacki, J.6
-
103
-
-
0037254010
-
Melatonin for ulcerative colitis?
-
Mann S. Melatonin for ulcerative colitis? Am J Gastroenterol 2003; 98: 232-3.
-
(2003)
Am J Gastroenterol
, vol.98
, pp. 232-233
-
-
Mann, S.1
-
104
-
-
0036245857
-
Melatonin triggers Crohn's disease symptoms
-
Calvo JR, Guerrero JM, Osuna C, Molinero P, Carrillo-Vico A. Melatonin triggers Crohn's disease symptoms. J Pineal Res 2002; 32: 277-8.
-
(2002)
J Pineal Res
, vol.32
, pp. 277-278
-
-
Calvo, J.R.1
Guerrero, J.M.2
Osuna, C.3
Molinero, P.4
Carrillo-Vico, A.5
-
105
-
-
51649109708
-
Melatonin usage in ulcerative colitis: A case report
-
Maldonado MD, Calvo JR. Melatonin usage in ulcerative colitis: a case report. J Pineal Res 2008; 45: 339-40.
-
(2008)
J Pineal Res
, vol.45
, pp. 339-340
-
-
Maldonado, M.D.1
Calvo, J.R.2
-
106
-
-
0026668042
-
Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
-
Takeshige K, Baba M, Tsuboi S, Noda T, Ohsumi Y. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction. J Cell Biol 1992; 119: 301-11
-
(1992)
J Cell Biol
, vol.119
, pp. 301-311
-
-
Takeshige, K.1
Baba, M.2
Tsuboi, S.3
Noda, T.4
Ohsumi, Y.5
-
107
-
-
0037005133
-
Autophagy in yeast: A review of the molecular machinery
-
Huang WP, Klionsky DJ. Autophagy in yeast: a review of the molecular machinery. Cell Struc Funct 2002; 27: 409-20
-
(2002)
Cell Struc Funct
, vol.27
, pp. 409-420
-
-
Huang, W.P.1
Klionsky, D.J.2
-
109
-
-
77953713630
-
C. elegans screen identifies autophagy genes specific to multicellular organisms
-
Tian Y, Li Z, Hu W, et al. C. elegans screen identifies autophagy genes specific to multicellular organisms. Cell. 2010; 141: 1042-55
-
(2010)
Cell
, vol.141
, pp. 1042-1055
-
-
Tian, Y.1
Li, Z.2
Hu, W.3
-
110
-
-
0041411115
-
Autophagic programmed cell death in Drosophila
-
Baehrecke EH. Autophagic programmed cell death in Drosophila. Cell Death Differ 2003; 10: 940-5
-
(2003)
Cell Death Differ
, vol.10
, pp. 940-945
-
-
Baehrecke, E.H.1
-
112
-
-
0033791650
-
Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells
-
Kim J, Klionsky DJ. Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells. Annu Rev Biochem 2000; 69: 303-42
-
(2000)
Annu Rev Biochem
, vol.69
, pp. 303-342
-
-
Kim, J.1
Klionsky, D.J.2
-
113
-
-
77951911179
-
Regulation of autophagy in mammals and its interplay with apoptosis
-
Fimia GM, Piacentini M. Regulation of autophagy in mammals and its interplay with apoptosis. Cell Mol Life Sci 2010; 67: 1581-8
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 1581-1588
-
-
Fimia, G.M.1
Piacentini, M.2
-
114
-
-
69349103147
-
Function and regulation of macroautophagy in plants
-
Bassham DC. Function and regulation of macroautophagy in plants. Biochim Biophys Acta 2009; 1793: 1397-403
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 1397-1403
-
-
Bassham, D.C.1
-
115
-
-
10744225487
-
A unified nomenclature for yeast autophagy-related genes
-
Klionsky DJ, Cregg JM, Dunn WA, et al. A unified nomenclature for yeast autophagy-related genes. Dev Cell 2003; 5: 539-45
-
(2003)
Dev Cell
, vol.5
, pp. 539-545
-
-
Klionsky, D.J.1
Cregg, J.M.2
Dunn, W.A.3
-
116
-
-
41049087959
-
Auto-phagy-physiology and pathophysiology
-
Uchiyama Y, Shibata M, Koike M, Yoshimura K, Sasaki M. Auto-phagy-physiology and pathophysiology. Histochem Cell Biol 2008; 129:407-20
-
(2008)
Histochem Cell Biol
, vol.129
, pp. 407-420
-
-
Uchiyama, Y.1
Shibata, M.2
Koike, M.3
Yoshimura, K.4
Sasaki, M.5
-
117
-
-
77953724901
-
A comprehensive glossary of autophagy-related molecules and processes
-
Klionsky DJ, Codogno P, Cuervo AM, et al. A comprehensive glossary of autophagy-related molecules and processes. Autophagy 2010; 6: 438-48
-
(2010)
Autophagy
, vol.6
, pp. 438-448
-
-
Klionsky, D.J.1
Codogno, P.2
Cuervo, A.M.3
-
119
-
-
0034683568
-
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
-
Kamada Y, Funakoshi T, Shintani T, Nagano K, Ohsumi M, Oh-sumi Y. Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 2000; 150: 1507-13
-
(2000)
J Cell Biol
, vol.150
, pp. 1507-1513
-
-
Kamada, Y.1
Funakoshi, T.2
Shintani, T.3
Nagano, K.4
Ohsumi, M.5
Oh-Sumi, Y.6
-
120
-
-
65249119430
-
Nutrientdependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
-
Hosokawa N, Hara T, Kaizuka T, et al. Nutrientdependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell 2009; 20: 1981-91
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
-
121
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
Jung CH, Jun CB, Ro SH, et al. ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell 2009; 20: 1992-2003
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
-
122
-
-
77953543377
-
The Beclin1-VPS34 complex-at the crossroads of autophagy and beyond
-
Funderburk SF, Wang QJ, Yue Z. The Beclin1-VPS34 complex-at the crossroads of autophagy and beyond. Trends Cell Biol 2010; 20: 355-62
-
(2010)
Trends Cell Biol
, vol.20
, pp. 355-362
-
-
Funderburk, S.F.1
Wang, Q.J.2
Yue, Z.3
-
123
-
-
0035286734
-
Molecular dissection of autophagy: Two ubiquitin-like systems
-
Ohsumi, Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat Rev Mol Cell Biol 2001; 2: 211-6
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 211-216
-
-
Ohsumi, Y.1
-
124
-
-
35848970794
-
Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease
-
Massey DC, Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy 2007; 3: 649-51
-
(2007)
Autophagy
, vol.3
, pp. 649-651
-
-
Massey, D.C.1
Parkes, M.2
-
125
-
-
38949108670
-
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
-
Klionsky DJ, Abeliovich H, Agostinis P, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 2008; 4: 151-175
-
(2008)
Autophagy
, vol.4
, pp. 151-175
-
-
Klionsky, D.J.1
Abeliovich, H.2
Agostinis, P.3
-
126
-
-
34548082024
-
A cycling protein complex required for selective autophagy
-
Legakis JE, Yen WL, Klionsky DJ. A cycling protein complex required for selective autophagy. Autophagy 2007; 3: 422-32
-
(2007)
Autophagy
, vol.3
, pp. 422-432
-
-
Legakis, J.E.1
Yen, W.L.2
Klionsky, D.J.3
-
127
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G, Mariño G, Levine B. Autophagy and the integrated stress response. Mol Cell 2010; 40: 280-93
-
(2010)
Mol Cell
, vol.40
, pp. 280-293
-
-
Kroemer, G.1
Mariño, G.2
Levine, B.3
-
128
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
Inoki K, Li Y, Zhu T, Wu J, Guan KL. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 2002; 4: 648-57
-
(2002)
Nat Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
129
-
-
77950501014
-
mTOR regulation of autophagy
-
Jung CH, Ro SH, Cao J, Otto NM, Kim DH. mTOR regulation of autophagy. FEBS Lett 2010; 584: 1287-95
-
(2010)
FEBS Lett
, vol.584
, pp. 1287-1295
-
-
Jung, C.H.1
Ro, S.H.2
Cao, J.3
Otto, N.M.4
Kim, D.H.5
-
130
-
-
44949237240
-
JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
-
Wei Y, Pattingre S, Sinha S, Bassik M, Levine B. JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 2008; 30: 678-88
-
(2008)
Mol Cell
, vol.30
, pp. 678-688
-
-
Wei, Y.1
Pattingre, S.2
Sinha, S.3
Bassik, M.4
Levine, B.5
-
131
-
-
63849149937
-
LKB1 and AMP-activated protein kinase control of mTOR signalling and growth
-
Shaw R.J. LKB1 and AMP-activated protein kinase control of mTOR signalling and growth. Acta Physiol 2009; 196: 65-80
-
(2009)
Acta Physiol
, vol.196
, pp. 65-80
-
-
Shaw, R.J.1
-
133
-
-
14844303381
-
Extensive involvement of autophagy in Alzheimer disease: An immuno-electron microscopy study
-
Nixon RA, Wegiel J, Kumar A, et al. Extensive involvement of autophagy in Alzheimer disease: An immuno-electron microscopy study. J Neuropathol Exp Neurol 2005; 64: 113-22
-
(2005)
J Neuropathol Exp Neurol
, vol.64
, pp. 113-122
-
-
Nixon, R.A.1
Wegiel, J.2
Kumar, A.3
-
134
-
-
59649114573
-
Autophagic clearance of aggregate-prone proteins associated with neurodegeneration
-
Sarkar S, Ravikumar B, Rubinsztein C. Autophagic clearance of aggregate-prone proteins associated with neurodegeneration. Methods Enzymol 2009; 453: 83-110
-
(2009)
Methods Enzymol
, vol.453
, pp. 83-110
-
-
Sarkar, S.1
Ravikumar, B.2
Rubinsztein, C.3
-
135
-
-
79960308079
-
Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives
-
Cheung ZH, Ip NY. Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives. J Neurochem 2011; 118: 317-25
-
(2011)
J Neurochem
, vol.118
, pp. 317-325
-
-
Cheung, Z.H.1
Ip, N.Y.2
-
136
-
-
84980052506
-
Protein aggregation and degradation mechanisms in neurodegenera-tive diseases
-
Takalo M, Salminen A, Soininen H, Hiltunen M, Haapasalo A. Protein aggregation and degradation mechanisms in neurodegenera-tive diseases. Am J Neurodegener Dis 2013; 2: 1-14
-
(2013)
Am J Neurodegener Dis
, vol.2
, pp. 1-14
-
-
Takalo, M.1
Salminen, A.2
Soininen, H.3
Hiltunen, M.4
Haapasalo, A.5
-
137
-
-
0442274441
-
Autophagic vacuolar myophaties
-
Nishino I. Autophagic vacuolar myophaties. Curr Neurol Neurosci Rep 2003; 3: 64-9
-
(2003)
Curr Neurol Neurosci Rep
, vol.3
, pp. 64-69
-
-
Nishino, I.1
-
138
-
-
0442323561
-
Autophagy: In sickness and in health
-
Cuervo AM. Autophagy: in sickness and in health. Trends Cell Biol 2004; 14: 70-7
-
(2004)
Trends Cell Biol
, vol.14
, pp. 70-77
-
-
Cuervo, A.M.1
-
141
-
-
60749115617
-
Recent advances in IBD patho-genesis: Genetics and immunology
-
Shih DQ, Targan SR, McGovern D. Recent advances in IBD patho-genesis: Genetics and immunology. Curr Gastroenterol Rep 2008; 10: 568-75
-
(2008)
Curr Gastroenterol Rep
, vol.10
, pp. 568-575
-
-
Shih, D.Q.1
Targan, S.R.2
McGovern, D.3
-
142
-
-
73449089391
-
Inflammatory bowel disease: Review from the aspect of genetics
-
Ishiara S, Aziz MM, Yuki T, Kazumori H, Kinoshita Y. Inflammatory bowel disease: review from the aspect of genetics. J Gastroen-terol 2009; 44: 1097-108
-
(2009)
J Gastroen-terol
, vol.44
, pp. 1097-1108
-
-
Ishiara, S.1
Aziz, M.M.2
Yuki, T.3
Kazumori, H.4
Kinoshita, Y.5
-
143
-
-
79955555098
-
Autophagy, microbial sensing, endoplas-mic reticulum stress, and epithelial function in inflammatory bowel disease
-
Kaser A, Blumberg RS. Autophagy, microbial sensing, endoplas-mic reticulum stress, and epithelial function in inflammatory bowel disease. Gastroenterology 2011; 140:1738-47
-
(2011)
Gastroenterology
, vol.140
, pp. 1738-1747
-
-
Kaser, A.1
Blumberg, R.S.2
-
144
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine B, Mizushima N, Virgin HW. Autophagy in immunity and inflammation. Nature 2011; 469: 323-35
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
146
-
-
80052641505
-
Crohn's disease: NOD2, autophagy and ER stress converge
-
Fritz T, Niederreiter L, Adolph T, Blumberg RS, Kaser A. Crohn's disease: NOD2, autophagy and ER stress converge. Gut 2011; 60: 1580-8
-
(2011)
Gut
, vol.60
, pp. 1580-1588
-
-
Fritz, T.1
Niederreiter, L.2
Adolph, T.3
Blumberg, R.S.4
Kaser, A.5
-
147
-
-
84874108251
-
Immune aspects of the pathogenesis of inflammatory bowel disease
-
Hisamatsu T, Kanai T, Mikami Y, Yoneno K, Matsuoka K, Hibi T. Immune aspects of the pathogenesis of inflammatory bowel disease. Pharmacol Ther 2013; 137: 283-97
-
(2013)
Pharmacol Ther
, vol.137
, pp. 283-297
-
-
Hisamatsu, T.1
Kanai, T.2
Mikami, Y.3
Yoneno, K.4
Matsuoka, K.5
Hibi, T.6
-
148
-
-
50249086073
-
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
-
Kaser A, Lee AH, Franke A, et al. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell 2008; 134: 743-56
-
(2008)
Cell
, vol.134
, pp. 743-756
-
-
Kaser, A.1
Lee, A.H.2
Franke, A.3
-
149
-
-
34447629523
-
Innate and adaptive immunity through auto-phagy
-
Schmid D, Münz C. Innate and adaptive immunity through auto-phagy. Immunity 2007; 27: 11-21
-
(2007)
Immunity
, vol.27
, pp. 11-21
-
-
Schmid, D.1
Münz, C.2
-
150
-
-
1542283812
-
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
-
Mizushima N, Yamamoto A, Matsui M, Yoshimori T, Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker. Mol Biol Cell 2004; 15: 1101-11
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1101-1111
-
-
Mizushima, N.1
Yamamoto, A.2
Matsui, M.3
Yoshimori, T.4
Ohsumi, Y.5
-
151
-
-
79959271087
-
Intestinal homeostasis and its breakdown in inflammatory bowel disease
-
Maloy KJ, Powrie F. Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 2011; 474: 298-306
-
(2011)
Nature
, vol.474
, pp. 298-306
-
-
Maloy, K.J.1
Powrie, F.2
-
152
-
-
33947386684
-
Endoplasmic reticulum stress: A new pathway to induce autophagy
-
Yorimitsu T, Klionsky DJ. Endoplasmic reticulum stress: a new pathway to induce autophagy. Autophagy 2007; 3: 160-2
-
(2007)
Autophagy
, vol.3
, pp. 160-162
-
-
Yorimitsu, T.1
Klionsky, D.J.2
-
153
-
-
72549095406
-
Regulation mechanisms and signalling pathways of autophagy
-
He C, Klionsky DJ. Regulation mechanisms and signalling pathways of autophagy. Annu Rev Genet 2009; 43: 67-93
-
(2009)
Annu Rev Genet
, vol.43
, pp. 67-93
-
-
He, C.1
Klionsky, D.J.2
-
154
-
-
77955947900
-
Linking ER stress to autophagy: Potential implications for cancer therapy
-
doi:10.1155/2010/930509
-
Verfaillie T, Salazar M, Velasco G, Agostinis P. Linking ER stress to autophagy: potential implications for cancer therapy. Int J Cell Biol 2010; doi:10.1155/2010/930509
-
(2010)
Int J Cell Biol
-
-
Verfaillie, T.1
Salazar, M.2
Velasco, G.3
Agostinis, P.4
-
155
-
-
0035094262
-
Increased sensitivity to dex-tran sodium sulfate colitis in IRE1beta-deficient mice
-
Bertolotti A, Wang X, Novoa I, et al. Increased sensitivity to dex-tran sodium sulfate colitis in IRE1beta-deficient mice. J Clin Invest 2001; 107: 585-93
-
(2001)
J Clin Invest
, vol.107
, pp. 585-593
-
-
Bertolotti, A.1
Wang, X.2
Novoa, I.3
-
156
-
-
50449091647
-
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
-
McCarroll SA, Huett A, Kuballa SD, et al. Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet 2008; 40: 1107-12
-
(2008)
Nat Genet
, vol.40
, pp. 1107-1112
-
-
McCarroll, S.A.1
Huett, A.2
Kuballa, S.D.3
-
157
-
-
0032545292
-
A new protein conjugation system in human the counterpart of the yeast Apg12p conjugation system essential for autophagy
-
Mizushima N, Sugita H, Yoshimori T, Ohsumi Y. A new protein conjugation system in human the counterpart of the yeast Apg12p conjugation system essential for autophagy. J Biol Chem 1998; 273: 33889-92
-
(1998)
J Biol Chem
, vol.273
, pp. 33889-33892
-
-
Mizushima, N.1
Sugita, H.2
Yoshimori, T.3
Ohsumi, Y.4
-
158
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh T, Fujita N, Jang MH, et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature 2008; 456: 264-8
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
-
159
-
-
56249135538
-
A unique role for autophagy and Atg16L1 in Paneth cells in murine and human intestine
-
Cadwell K, Liu J, Brown S, et al. A unique role for autophagy and Atg16L1 in Paneth cells in murine and human intestine. Nature 2008; 456: 259-63
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.2
Brown, S.3
-
160
-
-
0030731743
-
Paneth cells and innate immunity in the crypt micro-environment
-
Ouellette AJ. Paneth cells and innate immunity in the crypt micro-environment. Gastroenterology 1997; 113: 1779-84
-
(1997)
Gastroenterology
, vol.113
, pp. 1779-1784
-
-
Ouellette, A.J.1
-
161
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
Singh SB, Davis S, Taylor GA, Deretic V. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 2006; 313: 1438-41
-
(2006)
Science
, vol.313
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, S.2
Taylor, G.A.3
Deretic, V.4
-
162
-
-
38449097465
-
The IFN-inducible GTPase LRG47 (Irgm1) negatively regulates TLR4-triggered proinflamma-tory cytokine production and prevents endotoxemia
-
Bafica A, Feng CG, Santiago HC, et al. The IFN-inducible GTPase LRG47 (Irgm1) negatively regulates TLR4-triggered proinflamma-tory cytokine production and prevents endotoxemia. J Immunol 2007; 179: 5514-22
-
(2007)
J Immunol
, vol.179
, pp. 5514-5522
-
-
Bafica, A.1
Feng, C.G.2
Santiago, H.C.3
-
163
-
-
77954754620
-
Autophagy and Crohn's disease: At the crossroads of infection, inflammation, immunity, and cancer
-
Brest P, Corcelle EA, Cesaro A, et al. Autophagy and Crohn's disease: at the crossroads of infection, inflammation, immunity, and cancer. Curr Mol Med 2010; 10: 486-502
-
(2010)
Curr Mol Med
, vol.10
, pp. 486-502
-
-
Brest, P.1
Corcelle, E.A.2
Cesaro, A.3
-
164
-
-
73849151394
-
NOD2 stimulation induces auto-phagy in dendritic cells influencing bacterial handling and antigen presentation
-
Cooney R, Baker J, Brain O, et al. NOD2 stimulation induces auto-phagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med 2010; 16: 90-7
-
(2010)
Nat Med
, vol.16
, pp. 90-97
-
-
Cooney, R.1
Baker, J.2
Brain, O.3
-
165
-
-
0037847511
-
Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis
-
Dubuquoy L, Jansson EA, Deeb S, et al. Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis. Gastroenterology 2003; 124: 1265-76
-
(2003)
Gastroenterology
, vol.124
, pp. 1265-1276
-
-
Dubuquoy, L.1
Jansson, E.A.2
Deeb, S.3
-
166
-
-
0347756655
-
Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA
-
Kelly D, Campbell JI, King TP, et al. Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA. Nat Immunol 2004; 5: 104-12
-
(2004)
Nat Immunol
, vol.5
, pp. 104-112
-
-
Kelly, D.1
Campbell, J.I.2
King, T.P.3
-
167
-
-
37549043217
-
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
-
Sanjuan MA, Dillon CP, Tait SW, et al. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature 2007; 450: 1253-7
-
(2007)
Nature
, vol.450
, pp. 1253-1257
-
-
Sanjuan, M.A.1
Dillon, C.P.2
Tait, S.W.3
-
168
-
-
10944253145
-
Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages
-
Gutierrez MG, Master SS, Singh SB, Taylor GA, Colombo MI, Deretic V. Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. Cell 2004; 119: 753-66
-
(2004)
Cell
, vol.119
, pp. 753-766
-
-
Gutierrez, M.G.1
Master, S.S.2
Singh, S.B.3
Taylor, G.A.4
Colombo, M.I.5
Deretic, V.6
-
169
-
-
2142752480
-
Cellular autophagy: Surrender, avoidance and subversion by microorganisms
-
Kirkegaard K, Taylor MP, Jackson WT. Cellular autophagy: surrender, avoidance and subversion by microorganisms. Nat Rev Mi-crobiol 2004; 2: 301-14
-
(2004)
Nat Rev Mi-crobiol
, vol.2
, pp. 301-314
-
-
Kirkegaard, K.1
Taylor, M.P.2
Jackson, W.T.3
-
170
-
-
80052146101
-
The machinery of Nod-like receptors: Refining the paths to immunity and cell death
-
Saleh M. The machinery of Nod-like receptors: refining the paths to immunity and cell death. Immunol Rev 2011; 243: 235-46
-
(2011)
Immunol Rev
, vol.243
, pp. 235-246
-
-
Saleh, M.1
-
171
-
-
19344373577
-
Lamp-2a facilitates MHC class II presentation of cytoplasmic antigens
-
Zhou D, Li P, Lin Y, et al. Lamp-2a facilitates MHC class II presentation of cytoplasmic antigens. Immunity 2005; 22: 571-81
-
(2005)
Immunity
, vol.22
, pp. 571-581
-
-
Zhou, D.1
Li, P.2
Lin, Y.3
-
172
-
-
20344361954
-
Autophagy promotes MHC class II presentation of peptides from intracellular source proteins
-
Dengjel J, Schoor O, Fischer R, et al. Autophagy promotes MHC class II presentation of peptides from intracellular source proteins. Proc Nat Acad Sci USA 2005; 102: 7922-7
-
(2005)
Proc Nat Acad Sci USA
, vol.102
, pp. 7922-7927
-
-
Dengjel, J.1
Schoor, O.2
Fischer, R.3
-
173
-
-
71849083952
-
Autophagy upregula-tion and loss of NF-kappaB in oxidative stress-related immunodefi-cient SAMP8 mice
-
Caballero B, Vega-Naredo I, Sierra V, et al. Autophagy upregula-tion and loss of NF-kappaB in oxidative stress-related immunodefi-cient SAMP8 mice. Mech Ageing Dev 2009; 130: 722-30
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 722-730
-
-
Caballero, B.1
Vega-Naredo, I.2
Sierra, V.3
-
174
-
-
77149160042
-
Melatonin protects N2a against ischemia/reperfusion injury through autophagy enhancement
-
Guo Y, Wang J, Wang Z, Yang Y, Wang X, Duan Q. Melatonin protects N2a against ischemia/reperfusion injury through autophagy enhancement. J Huazhong Univ Sci Technolog Med Sci 2010; 30: 1-7
-
(2010)
J Huazhong Univ Sci Technolog Med Sci
, vol.30
, pp. 1-7
-
-
Guo, Y.1
Wang, J.2
Wang, Z.3
Yang, Y.4
Wang, X.5
Duan, Q.6
-
175
-
-
84866247938
-
Melatonin-induced autophagy is associated with degradation of MyoD protein in C2C12 myoblast cells
-
Kim CH, Kim KH, Yoo YM. Melatonin-induced autophagy is associated with degradation of MyoD protein in C2C12 myoblast cells. J Pineal Res 2012; 53: 289-97
-
(2012)
J Pineal Res
, vol.53
, pp. 289-297
-
-
Kim, C.H.1
Kim, K.H.2
Yoo, Y.M.3
-
176
-
-
84879464170
-
Melatonin induces autophagy via an mTOR-dependent pathway and enhances clearance of mutant-TGFBIp
-
Choi SI, Kim KS, Oh JY, Jin JY, Lee GH, Kim EK. Melatonin induces autophagy via an mTOR-dependent pathway and enhances clearance of mutant-TGFBIp. J Pineal Res 2013; 54: 361-72
-
(2013)
J Pineal Res
, vol.54
, pp. 361-372
-
-
Choi, S.I.1
Kim, K.S.2
Oh, J.Y.3
Jin, J.Y.4
Lee, G.H.5
Kim, E.K.6
-
177
-
-
33645923392
-
Could melatonin unbalance the equilibrium between autophagy and invasive processes?
-
Coto-Montes A, Tomas-Zapico C. Could melatonin unbalance the equilibrium between autophagy and invasive processes? Autophagy 2006; 2: 126-8
-
(2006)
Autophagy
, vol.2
, pp. 126-128
-
-
Coto-Montes, A.1
Tomas-Zapico, C.2
-
178
-
-
33644903543
-
Ultrastructural clues for the protective effect of melatonin against oxidative damage in cerulein-induced pancreatitis
-
Esrefoglu M, Güi M, Ates B, et al. Ultrastructural clues for the protective effect of melatonin against oxidative damage in cerulein-induced pancreatitis. J Pineal Res 2006; 40: 92-7
-
(2006)
J Pineal Res
, vol.40
, pp. 92-97
-
-
Esrefoglu, M.1
Güi, M.2
Ates, B.3
-
179
-
-
42249099251
-
Melatonin represses oxidative stress-induced activation of the MAP kinase and mTOR signalling pathways in H4IIE hepatoma cells through inhibition of Ras
-
Kimball SR, Abbas A, Jefferson LS. Melatonin represses oxidative stress-induced activation of the MAP kinase and mTOR signalling pathways in H4IIE hepatoma cells through inhibition of Ras. J Pineal Res 2008; 44: 379-86
-
(2008)
J Pineal Res
, vol.44
, pp. 379-386
-
-
Kimball, S.R.1
Abbas, A.2
Jefferson, L.S.3
-
180
-
-
50849106068
-
Melatonin prevents ischemic brain injury through activation of the mTOR/p70S6 kinase signaling pathway
-
Koh PO. Melatonin prevents ischemic brain injury through activation of the mTOR/p70S6 kinase signaling pathway. Neurosci Lett 2008; 444: 74-8
-
(2008)
Neurosci Lett
, vol.444
, pp. 74-78
-
-
Koh, P.O.1
-
181
-
-
59149091414
-
Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells
-
Kongsuphol P, Mukda S, Nopparat C, et al. Melatonin attenuates methamphetamine-induced deactivation of the mammalian target of rapamycin signaling to induce autophagy in SK-N-SH cells. J Pineal Res 2009; 46: 199-206
-
(2009)
J Pineal Res
, vol.46
, pp. 199-206
-
-
Kongsuphol, P.1
Mukda, S.2
Nopparat, C.3
-
182
-
-
78349253806
-
The mechanism for the neuroprotective effect of melatonin against methanpheta-mine-induced autophagy
-
Nopparat C, Porter JE, Ebadi M, Govitrapong P. The mechanism for the neuroprotective effect of melatonin against methanpheta-mine-induced autophagy. J Pineal Res 2010; 49: 382-9
-
(2010)
J Pineal Res
, vol.49
, pp. 382-389
-
-
Nopparat, C.1
Porter, J.E.2
Ebadi, M.3
Govitrapong, P.4
-
183
-
-
77749336538
-
Melatonin suppresses cyclosporine A-induced autophagy in rat pituitary GH3 cells
-
Yoo Ym, Jeung EB. Melatonin suppresses cyclosporine A-induced autophagy in rat pituitary GH3 cells. J Pineal Res 2010; 48: 204-11
-
(2010)
J Pineal Res
, vol.48
, pp. 204-211
-
-
Ym, Y.1
Jeung, E.B.2
-
184
-
-
79960367670
-
Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells
-
Han F, Chen YX, Lu YM, et al. Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells. J Pineal Res 2011; 51: 124-35
-
(2011)
J Pineal Res
, vol.51
, pp. 124-135
-
-
Han, F.1
Chen, Y.X.2
Lu, Y.M.3
-
185
-
-
0004608585
-
Melatonin: Lowering the high price of free radicals
-
Reiter RJ. Melatonin: lowering the high price of free radicals. News Physiol Sci 2000; 15: 246-50
-
(2000)
News Physiol Sci
, vol.15
, pp. 246-250
-
-
Reiter, R.J.1
-
186
-
-
84864347965
-
Role of melatonin in the regulation of autophagy and mitophagy: A review
-
Coto-Montes A, Boga JA, Rosales-Corral S, Fuentes-Broto L, Tan DX, Reiter RJ. Role of melatonin in the regulation of autophagy and mitophagy: A review. Mol Cell Endocrinol 2012; 361: 12-23
-
(2012)
Mol Cell Endocrinol
, vol.361
, pp. 12-23
-
-
Coto-Montes, A.1
Boga, J.A.2
Rosales-Corral, S.3
Fuentes-Broto, L.4
Tan, D.X.5
Reiter, R.J.6
-
187
-
-
84864544220
-
Pharmacological control of autophagy: Therapeutic perspectives in inflammatory bowel disease and colorectal cancer
-
García-Mauriño S, Alcaide A, Dominguez C. Pharmacological control of autophagy: Therapeutic perspectives in inflammatory bowel disease and colorectal cancer. Curr Pharm Des 2012; 18: 3853-73
-
(2012)
Curr Pharm Des
, vol.18
, pp. 3853-3873
-
-
García-Mauriño, S.1
Alcaide, A.2
Dominguez, C.3
-
188
-
-
84858748850
-
Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and a-synuclein aggregation
-
Chang CF, Huang HJ, Lee HC, Hung KC, Wu RT, Lin AMY. Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and a-synuclein aggregation. J Pineal Res 2012; 52: 312-21
-
(2012)
J Pineal Res
, vol.52
, pp. 312-321
-
-
Chang, C.F.1
Huang, H.J.2
Lee, H.C.3
Hung, K.C.4
Wu, R.T.5
Lin, A.M.Y.6
-
189
-
-
83555174800
-
Melatonin protects against rotenone-induced cell injury via inhibition of Omi and Bax-mediated autophagy in Hela cells
-
Zhou H, Chen J, Lu X, et al. Melatonin protects against rotenone-induced cell injury via inhibition of Omi and Bax-mediated autophagy in Hela cells. J Pineal Res 2012; 52: 120-7
-
(2012)
J Pineal Res
, vol.52
, pp. 120-127
-
-
Zhou, H.1
Chen, J.2
Lu, X.3
-
190
-
-
83555173235
-
Beneficial effects of endogenous and exogenous melatonin on neural reconstruction and functional recovery in an animal model of spinal cord injury
-
Park S, Lee SK, Park K, et al. Beneficial effects of endogenous and exogenous melatonin on neural reconstruction and functional recovery in an animal model of spinal cord injury. J Pineal Res 2012; 52: 107-19
-
(2012)
J Pineal Res
, vol.52
, pp. 107-119
-
-
Park, S.1
Lee, S.K.2
Park, K.3
-
191
-
-
84864988984
-
Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity
-
Jeong JK, Moon MH, Lee YJ, Seol JW, Park SY. Melatonin-induced autophagy protects against human prion protein-mediated neurotoxicity. J Pineal Res 2012; 53: 138-46
-
(2012)
J Pineal Res
, vol.53
, pp. 138-146
-
-
Jeong, J.K.1
Moon, M.H.2
Lee, Y.J.3
Seol, J.W.4
Park, S.Y.5
-
192
-
-
84862791081
-
Involvement of melatonin in auto-phagy-mediated mouse hepatoma H22 cell survival
-
Liu C, Jia Z, Zhang X, et al. Involvement of melatonin in auto-phagy-mediated mouse hepatoma H22 cell survival. Int Immuno-pharmacol 2012; 12: 349-401
-
(2012)
Int Immuno-pharmacol
, vol.12
, pp. 349-401
-
-
Liu, C.1
Jia, Z.2
Zhang, X.3
-
193
-
-
80052629112
-
Melatonin reduces membrane rigidity and oxidative damage in the brain of SAMP8 mice
-
García JJ, Piñol-Ripoll G, Martínez-Ballarín E, et al. Melatonin reduces membrane rigidity and oxidative damage in the brain of SAMP8 mice. Neurobiol Aging 2011; 32: 2045-54
-
(2011)
Neurobiol Aging
, vol.32
, pp. 2045-2054
-
-
García, J.J.1
Piñol-Ripoll, G.2
Martínez-Ballarín, E.3
-
194
-
-
83555174326
-
Melatonin modulates autophagy through a redox-mediated action in female Syrian hamster Harderian gland controlling cell types and gland activity
-
Vega-Naredo I, Caballero B, Sierra V, et al. Melatonin modulates autophagy through a redox-mediated action in female Syrian hamster Harderian gland controlling cell types and gland activity. J Pineal Res 2012; 52: 80-92
-
(2012)
J Pineal Res
, vol.52
, pp. 80-92
-
-
Vega-Naredo, I.1
Caballero, B.2
Sierra, V.3
-
195
-
-
79960354764
-
New paradigms in chronic intestinal inflammation and colon cancer: Role of melatonin
-
Motilva V, García-Mauriño S, Talero E, Illanes M. New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin. J Pineal Res 2011; 51: 44-60
-
(2011)
J Pineal Res
, vol.51
, pp. 44-60
-
-
Motilva, V.1
García-Mauriño, S.2
Talero, E.3
Illanes, M.4
-
196
-
-
41549138483
-
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
-
Lee IH, Cao L, Mostoslavsky R, et al. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Nat Acad Sci USA 2008; 105: 3374-79
-
(2008)
Proc Nat Acad Sci USA
, vol.105
, pp. 3374-3379
-
-
Lee, I.H.1
Cao, L.2
Mostoslavsky, R.3
-
197
-
-
55549096745
-
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation
-
Lan F, Caciedo JM, Ruderman N, Ido Y. SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. J Biol Chem 2008; 283: 27628-35
-
(2008)
J Biol Chem
, vol.283
, pp. 27628-27635
-
-
Lan, F.1
Caciedo, J.M.2
Ruderman, N.3
Ido, Y.4
-
198
-
-
71549154751
-
Sirtuins, melatonin and cir-cadian rhythms: Building a bridge between aging and cancer
-
Jung-Hynes B, Reiter RJ, Ahmad N. Sirtuins, melatonin and cir-cadian rhythms: building a bridge between aging and cancer. J Pineal Res 2010, 48: 9-19
-
(2010)
J Pineal Res
, vol.48
, pp. 9-19
-
-
Jung-Hynes, B.1
Reiter, R.J.2
Ahmad, N.3
-
199
-
-
79960860869
-
The effect of an intracere-broventricular injection of metformin or AICAR on the plasma concentrations of melatonin in the ewe: Potential involvement of AMPK?
-
Menassol JB, Tautou C, Collet A, et al. The effect of an intracere-broventricular injection of metformin or AICAR on the plasma concentrations of melatonin in the ewe: potential involvement of AMPK? BMC Neurosci 2011; 12: 76
-
(2011)
BMC Neurosci
, vol.12
, pp. 76
-
-
Menassol, J.B.1
Tautou, C.2
Collet, A.3
-
200
-
-
84876717815
-
Rejuvenating sirtuins: The rise of a new family of cancer drug targets
-
Bruzzone S, Parenti MD, Grozio A, et al. Rejuvenating sirtuins: the rise of a new family of cancer drug targets. Curr Pharm Des 2013; 19: 614-23
-
(2013)
Curr Pharm Des
, vol.19
, pp. 614-623
-
-
Bruzzone, S.1
Parenti, M.D.2
Grozio, A.3
-
201
-
-
84885485876
-
SIRT1 inhibition by melatonin exerts antitumor activity in human osteosarcoma cells
-
Cheng Y, Cai L, Jiang P, et al. SIRT1 inhibition by melatonin exerts antitumor activity in human osteosarcoma cells. Eur J Pharmacol; 2013: 219-29
-
(2013)
Eur J Pharmacol
, pp. 219-229
-
-
Cheng, Y.1
Cai, L.2
Jiang, P.3
-
202
-
-
78651509603
-
Melatonin potentiates the neuroprotective properties of resveratrol against beta-amyloid-induced neurodegeneration by modulating AMP-activated protein kinase pathways
-
Kwon KJ, Kim HJ, Shin CY, Han SH. Melatonin potentiates the neuroprotective properties of resveratrol against beta-amyloid-induced neurodegeneration by modulating AMP-activated protein kinase pathways. J Clin Neurol 2010; 6: 127-37
-
(2010)
J Clin Neurol
, vol.6
, pp. 127-137
-
-
Kwon, K.J.1
Kim, H.J.2
Shin, C.Y.3
Han, S.H.4
-
203
-
-
79954422774
-
Melatonin promotes puromycin-induced apoptosis with activation of caspase-3 and 5'-adenosine monophosphate-activated kinase-alpha in human leukemia HL-60 cells
-
Koh W, Jeong SJ, Lee HJ, et al. Melatonin promotes puromycin-induced apoptosis with activation of caspase-3 and 5'-adenosine monophosphate-activated kinase-alpha in human leukemia HL-60 cells. J Pineal Res 2011; 50: 367-73
-
(2011)
J Pineal Res
, vol.50
, pp. 367-373
-
-
Koh, W.1
Jeong, S.J.2
Lee, H.J.3
-
204
-
-
84885190019
-
AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: A role for melatonin and trimetazidine cocktail
-
Zaouali MA, Boncompagni E, Reiter RJ, et al. AMPK involvement in endoplasmic reticulum stress and autophagy modulation after fatty liver graft preservation: a role for melatonin and trimetazidine cocktail. J Pineal Res 2013; 1: 65-78.
-
(2013)
J Pineal Res
, vol.1
, pp. 65-78
-
-
Zaouali, M.A.1
Boncompagni, E.2
Reiter, R.J.3
|