메뉴 건너뛰기




Volumn 177, Issue 2, 2009, Pages 128-136

Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats

Author keywords

Biomarkers; Colitis; Colorectal cancer; Melatonin; Rats

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; AZOXYMETHANE; CHOLESTEROL; DEXTRAN SULFATE; GLUCOSE; HIGH DENSITY LIPOPROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERLEUKIN 1BETA; LEPTIN; LOW DENSITY LIPOPROTEIN; MELATONIN; STAT3 PROTEIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VERY LOW DENSITY LIPOPROTEIN;

EID: 57649225896     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.10.047     Document Type: Article
Times cited : (61)

References (61)
  • 3
    • 36849040010 scopus 로고    scopus 로고
    • Melatonin-insulin interactions in patients with metabolic syndrome
    • Robeva R., Kirilov G., Tomova A., and Kumanov P. Melatonin-insulin interactions in patients with metabolic syndrome. J. Pineal Res. 44 (2008) 52-56
    • (2008) J. Pineal Res. , vol.44 , pp. 52-56
    • Robeva, R.1    Kirilov, G.2    Tomova, A.3    Kumanov, P.4
  • 7
    • 0242552333 scopus 로고    scopus 로고
    • Effects of exogenous melatonin-a review
    • Anisimov V.N. Effects of exogenous melatonin-a review. Toxicol. Pathol. 31 (2003) 589-603
    • (2003) Toxicol. Pathol. , vol.31 , pp. 589-603
    • Anisimov, V.N.1
  • 8
    • 0037844514 scopus 로고    scopus 로고
    • The role of pineal gland in breast cancer development
    • Anisimov V.N. The role of pineal gland in breast cancer development. Crit. Rev. Oncol. Hematol. 46 (2003) 221-234
    • (2003) Crit. Rev. Oncol. Hematol. , vol.46 , pp. 221-234
    • Anisimov, V.N.1
  • 10
    • 0034111475 scopus 로고    scopus 로고
    • Melatonin and colon carcinogenesis. III. Effect of melatonin on proliferative activity and apoptosis in colon mucosa and colon tumors induced by 1,2-dimethylhydrazine in rats
    • Anisimov V.N., Popovich I.G., Shtylik A.V., Zabezhinski M.A., Ben-Huh H., Gurevich P., Berman V., Tendler Y., and Zusman I. Melatonin and colon carcinogenesis. III. Effect of melatonin on proliferative activity and apoptosis in colon mucosa and colon tumors induced by 1,2-dimethylhydrazine in rats. Exp. Toxicol. Pathol. 52 (2000) 71-76
    • (2000) Exp. Toxicol. Pathol. , vol.52 , pp. 71-76
    • Anisimov, V.N.1    Popovich, I.G.2    Shtylik, A.V.3    Zabezhinski, M.A.4    Ben-Huh, H.5    Gurevich, P.6    Berman, V.7    Tendler, Y.8    Zusman, I.9
  • 11
    • 0031428105 scopus 로고    scopus 로고
    • Melatonin and colon carcinogenesis. I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats
    • Anisimov V.N., Popovich I.G., and Zabezhinski M.A. Melatonin and colon carcinogenesis. I. Inhibitory effect of melatonin on development of intestinal tumors induced by 1,2-dimethylhydrazine in rats. Carcinogenesis 18 (1997) 1549-1553
    • (1997) Carcinogenesis , vol.18 , pp. 1549-1553
    • Anisimov, V.N.1    Popovich, I.G.2    Zabezhinski, M.A.3
  • 12
    • 0034320122 scopus 로고    scopus 로고
    • Melatonin and colon carcinogenesis. IV. Effect of melatonin on proliferative activity and expression of apoptosis-related proteins in the spleen of rats exposed to 1,2-dimethylhydrazine
    • Kossoy G., Ben-Hur H., Popovich I., Zabezhinski M., Anisimov V., and Zusman I. Melatonin and colon carcinogenesis. IV. Effect of melatonin on proliferative activity and expression of apoptosis-related proteins in the spleen of rats exposed to 1,2-dimethylhydrazine. Oncol. Rep. 7 (2000) 1401-1405
    • (2000) Oncol. Rep. , vol.7 , pp. 1401-1405
    • Kossoy, G.1    Ben-Hur, H.2    Popovich, I.3    Zabezhinski, M.4    Anisimov, V.5    Zusman, I.6
  • 13
    • 2342618225 scopus 로고    scopus 로고
    • Chemopreventive effects of melatonin on diethylnitrosamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats
    • Rahman K.M.W., Sugie S., Watanabe T., Tanaka T., and Mori H. Chemopreventive effects of melatonin on diethylnitrosamine and phenobarbital-induced hepatocarcinogenesis in male F344 rats. Nutr. Cancer 47 (2003) 148-155
    • (2003) Nutr. Cancer , vol.47 , pp. 148-155
    • Rahman, K.M.W.1    Sugie, S.2    Watanabe, T.3    Tanaka, T.4    Mori, H.5
  • 14
    • 0033947238 scopus 로고    scopus 로고
    • Effect of melatonin on two stage skin carcinogenesis in Swiss mice
    • Kumar C.A., and Das U.N. Effect of melatonin on two stage skin carcinogenesis in Swiss mice. Med. Sci. Monit. 6 (2000) 471-475
    • (2000) Med. Sci. Monit. , vol.6 , pp. 471-475
    • Kumar, C.A.1    Das, U.N.2
  • 16
    • 0034983585 scopus 로고    scopus 로고
    • Anticarcinogenic actions of melatonin which involve antioxidative processes: comparison with other antioxidants
    • Karbownik M., Lewinski A., and Reiter R.J. Anticarcinogenic actions of melatonin which involve antioxidative processes: comparison with other antioxidants. Int. J. Biochem. Cell. Biol. 33 (2001) 735-753
    • (2001) Int. J. Biochem. Cell. Biol. , vol.33 , pp. 735-753
    • Karbownik, M.1    Lewinski, A.2    Reiter, R.J.3
  • 17
    • 0033606103 scopus 로고    scopus 로고
    • Effects of melatonin on N-nitroso-N-methylurea-induced carcinogenesis in rats and mutagenesis in vitro (Ames test and COMET assay)
    • Musatov S.A., Anisimov V.N., André V., Vigreux C., Godard T., and Sichel F. Effects of melatonin on N-nitroso-N-methylurea-induced carcinogenesis in rats and mutagenesis in vitro (Ames test and COMET assay). Cancer Lett. 138 (1999) 37-44
    • (1999) Cancer Lett. , vol.138 , pp. 37-44
    • Musatov, S.A.1    Anisimov, V.N.2    André, V.3    Vigreux, C.4    Godard, T.5    Sichel, F.6
  • 18
    • 3042820946 scopus 로고    scopus 로고
    • Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin
    • Blask D.E., Dauchy R.T., Sauer L.A., and Krause J.A. Melatonin uptake and growth prevention in rat hepatoma 7288CTC in response to dietary melatonin: melatonin receptor-mediated inhibition of tumor linoleic acid metabolism to the growth signaling molecule 13-hydroxyoctadecadienoic acid and the potential role of phytomelatonin. Carcinogenesis 25 (2004) 951-960
    • (2004) Carcinogenesis , vol.25 , pp. 951-960
    • Blask, D.E.1    Dauchy, R.T.2    Sauer, L.A.3    Krause, J.A.4
  • 19
    • 27644592833 scopus 로고    scopus 로고
    • Putting cancer to sleep at night: the neuroendocrine/circadian melatonin signal
    • Blask D.E., Dauchy R.T., and Sauer L.A. Putting cancer to sleep at night: the neuroendocrine/circadian melatonin signal. Endocrine 27 (2005) 179-188
    • (2005) Endocrine , vol.27 , pp. 179-188
    • Blask, D.E.1    Dauchy, R.T.2    Sauer, L.A.3
  • 20
    • 0038389797 scopus 로고    scopus 로고
    • Effects of melatonin on the expression of iNOS and COX-2 in rat models of colitis
    • Dong W.G., Mei Q., Yu J.P., Xu J.M., Xiang L., and Xu Y. Effects of melatonin on the expression of iNOS and COX-2 in rat models of colitis. World J. Gastroenterol. 9 (2003) 1307-1311
    • (2003) World J. Gastroenterol. , vol.9 , pp. 1307-1311
    • Dong, W.G.1    Mei, Q.2    Yu, J.P.3    Xu, J.M.4    Xiang, L.5    Xu, Y.6
  • 21
    • 25644449484 scopus 로고    scopus 로고
    • Melatonin reduces inflammatory injury through inhibiting NF-kappaB activation in rats with colitis
    • Li J.H., Yu J.P., Yu H.G., Xu X.M., Yu L.L., Liu J., and Luo H.S. Melatonin reduces inflammatory injury through inhibiting NF-kappaB activation in rats with colitis. Mediators Inflamm. 2005 (2005) 185-193
    • (2005) Mediators Inflamm. , vol.2005 , pp. 185-193
    • Li, J.H.1    Yu, J.P.2    Yu, H.G.3    Xu, X.M.4    Yu, L.L.5    Liu, J.6    Luo, H.S.7
  • 22
    • 22144498398 scopus 로고    scopus 로고
    • Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages
    • Mayo J.C., Sainz R.M., Tan D.X., Hardeland R., Leon J., Rodriguez C., and Reiter R.J. Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages. J. Neuroimmunol. 165 (2005) 139-149
    • (2005) J. Neuroimmunol. , vol.165 , pp. 139-149
    • Mayo, J.C.1    Sainz, R.M.2    Tan, D.X.3    Hardeland, R.4    Leon, J.5    Rodriguez, C.6    Reiter, R.J.7
  • 23
    • 57649145199 scopus 로고    scopus 로고
    • WHO Media Centre, Cancer, Fact sheet No. 297, WHO, 2006.
    • WHO Media Centre, Cancer, Fact sheet No. 297, WHO, 2006.
  • 24
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: back to Virchow?
    • Balkwill F., and Mantovani A. Inflammation and cancer: back to Virchow?. Lancet 357 (2001) 539-545
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 25
    • 33744955457 scopus 로고    scopus 로고
    • Colorectal cancer in inflammatory bowel disease: molecular and clinical considerations
    • Rubin D.T., and Parekh N. Colorectal cancer in inflammatory bowel disease: molecular and clinical considerations. Curr. Treat. Opt. Gastroenterol. 9 (2006) 211-220
    • (2006) Curr. Treat. Opt. Gastroenterol. , vol.9 , pp. 211-220
    • Rubin, D.T.1    Parekh, N.2
  • 26
    • 0344237231 scopus 로고    scopus 로고
    • A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
    • Tanaka T., Kohno H., Suzuki R., Yamada Y., Sugie S., and Mori H. A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate. Cancer Sci. 94 (2003) 965-973
    • (2003) Cancer Sci. , vol.94 , pp. 965-973
    • Tanaka, T.1    Kohno, H.2    Suzuki, R.3    Yamada, Y.4    Sugie, S.5    Mori, H.6
  • 27
    • 29744461120 scopus 로고    scopus 로고
    • Strain differences in the susceptibility to azoxymethane and dextran sodium sulfate-induced colon carcinogenesis in mice
    • Suzuki R., Kohno H., Sugie S., Nakagama H., and Tanaka T. Strain differences in the susceptibility to azoxymethane and dextran sodium sulfate-induced colon carcinogenesis in mice. Carcinogenesis 27 (2006) 162-169
    • (2006) Carcinogenesis , vol.27 , pp. 162-169
    • Suzuki, R.1    Kohno, H.2    Sugie, S.3    Nakagama, H.4    Tanaka, T.5
  • 28
    • 5044228671 scopus 로고    scopus 로고
    • Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate
    • Suzuki R., Kohno H., Sugie S., and Tanaka T. Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate. Cancer Sci. 95 (2004) 721-727
    • (2004) Cancer Sci. , vol.95 , pp. 721-727
    • Suzuki, R.1    Kohno, H.2    Sugie, S.3    Tanaka, T.4
  • 29
    • 34250628479 scopus 로고    scopus 로고
    • Global gene expression analysis of the mouse colonic mucosa treated with azoxymethane and dextran sodium sulfate
    • Suzuki R., Miyamoto S., Yasui Y., Sugie S., and Tanaka T. Global gene expression analysis of the mouse colonic mucosa treated with azoxymethane and dextran sodium sulfate. BMC Cancer 7 (2007) 84
    • (2007) BMC Cancer , vol.7 , pp. 84
    • Suzuki, R.1    Miyamoto, S.2    Yasui, Y.3    Sugie, S.4    Tanaka, T.5
  • 30
    • 33646401129 scopus 로고    scopus 로고
    • Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice
    • Kohno H., Suzuki R., Curini M., Epifano F., Maltese F., Gonzales S.P., and Tanaka T. Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis-related colon carcinogenesis in mice. Int. J. Cancer 118 (2006) 2936-2942
    • (2006) Int. J. Cancer , vol.118 , pp. 2936-2942
    • Kohno, H.1    Suzuki, R.2    Curini, M.3    Epifano, F.4    Maltese, F.5    Gonzales, S.P.6    Tanaka, T.7
  • 31
    • 34247855981 scopus 로고    scopus 로고
    • Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice
    • Kohno H., Suzuki R., Yasui Y., Miyamoto S., Wakabayashi K., and Tanaka T. Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice. Clin. Cancer Res. 13 (2007) 2519-2525
    • (2007) Clin. Cancer Res. , vol.13 , pp. 2519-2525
    • Kohno, H.1    Suzuki, R.2    Yasui, Y.3    Miyamoto, S.4    Wakabayashi, K.5    Tanaka, T.6
  • 32
    • 15844376480 scopus 로고    scopus 로고
    • Beta-Catenin mutations in a mouse model of inflammation-related colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sodium sulfate
    • Kohno H., Suzuki R., Sugie S., and Tanaka T. Beta-Catenin mutations in a mouse model of inflammation-related colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sodium sulfate. Cancer Sci. 2005 (2005) 69-76
    • (2005) Cancer Sci. , vol.2005 , pp. 69-76
    • Kohno, H.1    Suzuki, R.2    Sugie, S.3    Tanaka, T.4
  • 33
    • 13444261395 scopus 로고    scopus 로고
    • Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, cyclooxygenase-2 and inducible nitric oxide synthase
    • Tanaka T., Suzuki R., Kohno H., Sugie S., Takahashi M., and Wakabayashi K. Colonic adenocarcinomas rapidly induced by the combined treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and dextran sodium sulfate in male ICR mice possess beta-catenin gene mutations and increases immunoreactivity for beta-catenin, cyclooxygenase-2 and inducible nitric oxide synthase. Carcinogenesis 26 (2005) 229-238
    • (2005) Carcinogenesis , vol.26 , pp. 229-238
    • Tanaka, T.1    Suzuki, R.2    Kohno, H.3    Sugie, S.4    Takahashi, M.5    Wakabayashi, K.6
  • 34
    • 27944442806 scopus 로고    scopus 로고
    • Dextran sodium sulfate strongly promotes colorectal carcinogenesis in Apc(Min/+) mice: inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms
    • Tanaka T., Kohno H., Suzuki R., Hata K., Sugie S., Niho N., Sakano K., Takahashi M., and Wakabayashi K. Dextran sodium sulfate strongly promotes colorectal carcinogenesis in Apc(Min/+) mice: inflammatory stimuli by dextran sodium sulfate results in development of multiple colonic neoplasms. Int. J. Cancer 118 (2006) 25-34
    • (2006) Int. J. Cancer , vol.118 , pp. 25-34
    • Tanaka, T.1    Kohno, H.2    Suzuki, R.3    Hata, K.4    Sugie, S.5    Niho, N.6    Sakano, K.7    Takahashi, M.8    Wakabayashi, K.9
  • 35
    • 27844562225 scopus 로고    scopus 로고
    • Prevention of human cancer by modulation of chronic inflammatory processes
    • Ohshima H., Tazawa H., Sylla B.S., and Sawa T. Prevention of human cancer by modulation of chronic inflammatory processes. Mutat. Res. 591 (2005) 110-122
    • (2005) Mutat. Res. , vol.591 , pp. 110-122
    • Ohshima, H.1    Tazawa, H.2    Sylla, B.S.3    Sawa, T.4
  • 36
    • 0346656706 scopus 로고    scopus 로고
    • Oxidative DNA damage in the mucosa of ulcerative colitis increases with disease duration and dysplasia
    • D'Inca R., Cardin R., Benazzato L., Angriman I., Martines D., and Sturniolo G.C. Oxidative DNA damage in the mucosa of ulcerative colitis increases with disease duration and dysplasia. Inflamm. Bowel Dis. 10 (2004) 23-27
    • (2004) Inflamm. Bowel Dis. , vol.10 , pp. 23-27
    • D'Inca, R.1    Cardin, R.2    Benazzato, L.3    Angriman, I.4    Martines, D.5    Sturniolo, G.C.6
  • 37
    • 33748139379 scopus 로고    scopus 로고
    • Chemoprevention: risk reduction with medical therapy of inflammatory bowel disease
    • Chan E.P., and Lichtenstein G.R. Chemoprevention: risk reduction with medical therapy of inflammatory bowel disease. Gastroenterol. Clin. N. Am. 35 (2006) 675-712
    • (2006) Gastroenterol. Clin. N. Am. , vol.35 , pp. 675-712
    • Chan, E.P.1    Lichtenstein, G.R.2
  • 38
    • 48549097778 scopus 로고    scopus 로고
    • A new medium-term rat colorectal bioassay applying neoplastic lesions as end points for detection of carcinogenesis modifiers effects with weak or controversial modifiers
    • Cho Y.M., Imai T., Ota Y., Hasumura M., Takami S., Hirose M., and Nishikawa A. A new medium-term rat colorectal bioassay applying neoplastic lesions as end points for detection of carcinogenesis modifiers effects with weak or controversial modifiers. Toxicol. Pathol. 36 (2008) 459-464
    • (2008) Toxicol. Pathol. , vol.36 , pp. 459-464
    • Cho, Y.M.1    Imai, T.2    Ota, Y.3    Hasumura, M.4    Takami, S.5    Hirose, M.6    Nishikawa, A.7
  • 39
    • 0035866756 scopus 로고    scopus 로고
    • T. Tanaka, H. Kohno, S. Yoshitani, S. Takashima, A. Okumura, A. Murakami, M. Hosokawa, Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats, Cancer Res. 61 (2001), 2424-2428.
    • T. Tanaka, H. Kohno, S. Yoshitani, S. Takashima, A. Okumura, A. Murakami, M. Hosokawa, Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats, Cancer Res. 61 (2001), 2424-2428.
  • 40
    • 37849009999 scopus 로고    scopus 로고
    • Molecular markers and targets for colorectal cancer prevention
    • Janakiram N.B., and Rao C.V. Molecular markers and targets for colorectal cancer prevention. Acta Pharmacol. Sin. 29 (2008) 1-20
    • (2008) Acta Pharmacol. Sin. , vol.29 , pp. 1-20
    • Janakiram, N.B.1    Rao, C.V.2
  • 41
    • 63149135635 scopus 로고    scopus 로고
    • Y. Yasui, M. Kim, T. Tanaka, Colorectal carcinogenesis and suppression of tumor development by inhibition of enzymes and molecular targets, Curr. Enzyme Inhib., (2009) in press.
    • Y. Yasui, M. Kim, T. Tanaka, Colorectal carcinogenesis and suppression of tumor development by inhibition of enzymes and molecular targets, Curr. Enzyme Inhib., (2009) in press.
  • 42
    • 0016374178 scopus 로고
    • Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats
    • Ward J.M. Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats. Lab. Invest. 30 (1974) 505-513
    • (1974) Lab. Invest. , vol.30 , pp. 505-513
    • Ward, J.M.1
  • 43
    • 35348842802 scopus 로고    scopus 로고
    • A lipophilic statin, pitavastatin, suppresses inflammation-associated mouse colon carcinogenesis
    • Yasui Y., Suzuki R., Miyamoto S., Tsukamoto T., Sugie S., Kohno H., and Tanaka T. A lipophilic statin, pitavastatin, suppresses inflammation-associated mouse colon carcinogenesis. Int. J. Cancer 121 (2007) 2331-2339
    • (2007) Int. J. Cancer , vol.121 , pp. 2331-2339
    • Yasui, Y.1    Suzuki, R.2    Miyamoto, S.3    Tsukamoto, T.4    Sugie, S.5    Kohno, H.6    Tanaka, T.7
  • 45
    • 1842609802 scopus 로고    scopus 로고
    • Melatonin reduces cholesterol accumulation and prooxidant state induced by high cholesterol diet in the plasma, the liver and probably in the aorta of C57BL/6J mice
    • Sener G., Balkan J., Cevikbaş U., Keyer-Uysal M., and Uysal M. Melatonin reduces cholesterol accumulation and prooxidant state induced by high cholesterol diet in the plasma, the liver and probably in the aorta of C57BL/6J mice. J. Pineal Res. 36 (2004) 212-216
    • (2004) J. Pineal Res. , vol.36 , pp. 212-216
    • Sener, G.1    Balkan, J.2    Cevikbaş, U.3    Keyer-Uysal, M.4    Uysal, M.5
  • 47
    • 33745932460 scopus 로고    scopus 로고
    • Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding
    • Deng W.G., Tang S.T., Tseng H.P., and Wu K.K. Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding. Blood 108 (2006) 518-524
    • (2006) Blood , vol.108 , pp. 518-524
    • Deng, W.G.1    Tang, S.T.2    Tseng, H.P.3    Wu, K.K.4
  • 48
    • 25144490062 scopus 로고    scopus 로고
    • Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands
    • Kohno H., Suzuki R., Sugie S., and Tanaka T. Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands. BMC Cancer 5 (2005) 46
    • (2005) BMC Cancer , vol.5 , pp. 46
    • Kohno, H.1    Suzuki, R.2    Sugie, S.3    Tanaka, T.4
  • 49
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • Aggarwal B.B., and Shishodia S. Molecular targets of dietary agents for prevention and therapy of cancer. Biochem. Pharmacol. 71 (2006) 1397-1421
    • (2006) Biochem. Pharmacol. , vol.71 , pp. 1397-1421
    • Aggarwal, B.B.1    Shishodia, S.2
  • 53
    • 16644390869 scopus 로고    scopus 로고
    • The p50-p50 NF-kappaB complex as a stimulus-specific repressor of gene activation
    • Tong X., Yin L., Washington R., Rosenberg D.W., and Giardina C. The p50-p50 NF-kappaB complex as a stimulus-specific repressor of gene activation. Mol. Cell. Biochem. 265 (2004) 171-183
    • (2004) Mol. Cell. Biochem. , vol.265 , pp. 171-183
    • Tong, X.1    Yin, L.2    Washington, R.3    Rosenberg, D.W.4    Giardina, C.5
  • 54
    • 23444452377 scopus 로고    scopus 로고
    • Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma, correlation with clinicopathological factors
    • Kusaba T., Nakayama T., Yamazumi K., Yakata Y., Yoshizaki A., Nagayasu T., and Sekine I. Expression of p-STAT3 in human colorectal adenocarcinoma and adenoma, correlation with clinicopathological factors. J. Clin. Pathol. 58 (2005) 833-838
    • (2005) J. Clin. Pathol. , vol.58 , pp. 833-838
    • Kusaba, T.1    Nakayama, T.2    Yamazumi, K.3    Yakata, Y.4    Yoshizaki, A.5    Nagayasu, T.6    Sekine, I.7
  • 55
    • 33745686647 scopus 로고    scopus 로고
    • Interleukin-6 production by leptin treatment promotes cell proliferation in an Apc(Min/+) colon epithelial cell line
    • Fenton J.I., Hursting S.D., Perkins S.N., and Hord N.G. Interleukin-6 production by leptin treatment promotes cell proliferation in an Apc(Min/+) colon epithelial cell line. Carcinogenesis 27 (2006) 1507-1515
    • (2006) Carcinogenesis , vol.27 , pp. 1507-1515
    • Fenton, J.I.1    Hursting, S.D.2    Perkins, S.N.3    Hord, N.G.4
  • 56
    • 56149118587 scopus 로고    scopus 로고
    • Melatonin reduces the expression of chemokines in rat with trinitrobenzene sulfonic acid-induced colitis
    • Li J.H., Zhou W., Liu K., Li H.X., and Wang L. Melatonin reduces the expression of chemokines in rat with trinitrobenzene sulfonic acid-induced colitis. Saudi Med. J. 29 (2008) 1088-1094
    • (2008) Saudi Med. J. , vol.29 , pp. 1088-1094
    • Li, J.H.1    Zhou, W.2    Liu, K.3    Li, H.X.4    Wang, L.5
  • 57
    • 33646901838 scopus 로고    scopus 로고
    • alpha-Tocopherol protects against alpha-naphthylisothiocyanate-induced hepatotoxicity in rats less effectively than melatonin
    • Ohta Y., Kongo-Nishimura M., Imai Y., Matsura T., Kitagawa A., and Yamada K. alpha-Tocopherol protects against alpha-naphthylisothiocyanate-induced hepatotoxicity in rats less effectively than melatonin. Chem. Biol. Interact. 131 (2006) 115-124
    • (2006) Chem. Biol. Interact. , vol.131 , pp. 115-124
    • Ohta, Y.1    Kongo-Nishimura, M.2    Imai, Y.3    Matsura, T.4    Kitagawa, A.5    Yamada, K.6
  • 58
    • 33846927059 scopus 로고    scopus 로고
    • Melatonin attenuates disruption of serum cholesterol status in rats with a single alpha-naphthylisothiocyanate treatment
    • Ohta Y., Kongo-Nishimura M., Imai Y., and Kitagawa A. Melatonin attenuates disruption of serum cholesterol status in rats with a single alpha-naphthylisothiocyanate treatment. J. Pineal Res. 42 (2007) 159-165
    • (2007) J. Pineal Res. , vol.42 , pp. 159-165
    • Ohta, Y.1    Kongo-Nishimura, M.2    Imai, Y.3    Kitagawa, A.4
  • 59
    • 0036164051 scopus 로고    scopus 로고
    • Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of Delta-5 desaturase activity
    • Nishida S., Segawa T., Murai I., and Nakagawa S. Long-term melatonin administration reduces hyperinsulinemia and improves the altered fatty-acid compositions in type 2 diabetic rats via the restoration of Delta-5 desaturase activity. J. Pineal Res. 32 (2002) 26-33
    • (2002) J. Pineal Res. , vol.32 , pp. 26-33
    • Nishida, S.1    Segawa, T.2    Murai, I.3    Nakagawa, S.4
  • 61
    • 33846457025 scopus 로고    scopus 로고
    • Intake of melatonin is associated with amelioration of physiological changes, both metabolic and morphological pathologies associated with obesity: an animal model
    • Hussein M.R., Ahmed O.G., Hassan A.F., and Ahmed M.A. Intake of melatonin is associated with amelioration of physiological changes, both metabolic and morphological pathologies associated with obesity: an animal model. Int. J. Exp. Pathol. 88 (2007) 19-29
    • (2007) Int. J. Exp. Pathol. , vol.88 , pp. 19-29
    • Hussein, M.R.1    Ahmed, O.G.2    Hassan, A.F.3    Ahmed, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.