ER stress is implicated in mitochondrial dysfunction-induced apoptosis of pancreatic beta cells

Molecules and Cells

Volumn 30, Issue 6, 2010, Pages 545-549

  Lee, June Woo ^a,b   Kim, Won Ho ^b   Yeo, Jiyoung ^a   Jung, Myeong Ho ^a  

^a Pusan National University   (South Korea)

^b Korea National Institute of Health   (South Korea)

Author keywords

AMP activated protein kinase (AMPK); Apoptosis; Endoplasmic reticulum (ER) stress; Mitochondrial dysfunction; Nitric oxide (NO); Pancreatic cells

Indexed keywords

CITRININ; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; JANUS KINASE; OLIGOMYCIN; ANTIMYCIN A1; DDIT3 PROTEIN, MOUSE; DRUG DERIVATIVE; ENDOPLASMIN; HEAT SHOCK PROTEIN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MOLECULAR CHAPERONE GRP78; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; INHIBITION KINETICS; INSULIN RELEASE; INSULINOMA; METABOLIC STRESS; MITOCHONDRION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL LINE; DRUG EFFECT; ENDOPLASMIC RETICULUM; METABOLISM; PATHOLOGY; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIMYCIN A; APOPTOSIS; CELL LINE; ENDOPLASMIC RETICULUM; HEAT-SHOCK PROTEINS; INSULIN; INSULIN-SECRETING CELLS; MAP KINASE KINASE 4; MEMBRANE GLYCOPROTEINS; MICE; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OLIGOMYCINS; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTOR CHOP;

EID: 79957689114     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-010-0161-5     Document Type: Article

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