-
1
-
-
34548125305
-
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
-
E.V. Acosta-Rodriguez, G. Napolitani, A. Lanzavecchia, and F. Sallusto Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells Nat Immunol 8 2007 942 949
-
(2007)
Nat Immunol
, vol.8
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
2
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
C.A. Anderson, G. Boucher, C.W. Lees, A. Franke, M. D'Amato, and K.D. Taylor Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 Nat Genet 43 2011 246 252
-
(2011)
Nat Genet
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
Franke, A.4
D'Amato, M.5
Taylor, K.D.6
-
3
-
-
84865494677
-
Systematic review: Faecal microbiota transplantation in the management of inflammatory bowel disease
-
J.L. Anderson, R.J. Edney, and K. Whelan Systematic review: Faecal microbiota transplantation in the management of inflammatory bowel disease Aliment Pharmacol Ther 36 2012 503 516
-
(2012)
Aliment Pharmacol Ther
, vol.36
, pp. 503-516
-
-
Anderson, J.L.1
Edney, R.J.2
Whelan, K.3
-
4
-
-
79959835543
-
Comparison of the fecal microbiota profiles between ulcerative colitis and Crohn's disease using terminal restriction fragment length polymorphism analysis
-
A. Andoh, H. Imaeda, T. Aomatsu, O. Inatomi, S. Bamba, and M. Sasaki Comparison of the fecal microbiota profiles between ulcerative colitis and Crohn's disease using terminal restriction fragment length polymorphism analysis J Gastroenterol 46 2011 479 486
-
(2011)
J Gastroenterol
, vol.46
, pp. 479-486
-
-
Andoh, A.1
Imaeda, H.2
Aomatsu, T.3
Inatomi, O.4
Bamba, S.5
Sasaki, M.6
-
5
-
-
58649086521
-
Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages
-
A. Andou, T. Hisamatsu, S. Okamoto, H. Chinen, N. Kamada, and T. Kobayashi Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages Gastroenterology 136 564-574 2009 e562
-
(2009)
Gastroenterology
, vol.136
, Issue.564-574
, pp. 562
-
-
Andou, A.1
Hisamatsu, T.2
Okamoto, S.3
Chinen, H.4
Kamada, N.5
Kobayashi, T.6
-
6
-
-
77954362764
-
Severe ulcerative colitis after rituximab therapy
-
D.S. Ardelean, T. Gonska, S. Wires, E. Cutz, A. Griffiths, and E. Harvey Severe ulcerative colitis after rituximab therapy Pediatrics 126 2010 e243 e246
-
(2010)
Pediatrics
, vol.126
-
-
Ardelean, D.S.1
Gonska, T.2
Wires, S.3
Cutz, E.4
Griffiths, A.5
Harvey, E.6
-
7
-
-
85027927719
-
Enterotypes of the human gut microbiome
-
M. Arumugam, J. Raes, E. Pelletier, D. Le Paslier, T. Yamada, and D.R. Mende Enterotypes of the human gut microbiome Nature 473 2011 174 180
-
(2011)
Nature
, vol.473
, pp. 174-180
-
-
Arumugam, M.1
Raes, J.2
Pelletier, E.3
Le Paslier, D.4
Yamada, T.5
Mende, D.R.6
-
8
-
-
53649100675
-
ATP drives lamina propria T (H)17 cell differentiation
-
K. Atarashi, J. Nishimura, T. Shima, Y. Umesaki, M. Yamamoto, and M. Onoue ATP drives lamina propria T (H)17 cell differentiation Nature 455 2008 808 812
-
(2008)
Nature
, vol.455
, pp. 808-812
-
-
Atarashi, K.1
Nishimura, J.2
Shima, T.3
Umesaki, Y.4
Yamamoto, M.5
Onoue, M.6
-
9
-
-
85027947787
-
Induction of colonic regulatory T cells by indigenous Clostridium species
-
K. Atarashi, T. Tanoue, T. Shima, A. Imaoka, T. Kuwahara, and Y. Momose Induction of colonic regulatory T cells by indigenous Clostridium species Science 331 2011 337 341
-
(2011)
Science
, vol.331
, pp. 337-341
-
-
Atarashi, K.1
Tanoue, T.2
Shima, T.3
Imaoka, A.4
Kuwahara, T.5
Momose, Y.6
-
10
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
J.C. Barrett, S. Hansoul, D.L. Nicolae, J.H. Cho, R.H. Duerr, and J.D. Rioux Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease Nat Genet 40 2008 955 962
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
Rioux, J.D.6
-
11
-
-
0035094262
-
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice
-
A. Bertolotti, X. Wang, I. Novoa, R. Jungreis, K. Schlessinger, and J.H. Cho Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice J Clin Invest 107 2001 585 593
-
(2001)
J Clin Invest
, vol.107
, pp. 585-593
-
-
Bertolotti, A.1
Wang, X.2
Novoa, I.3
Jungreis, R.4
Schlessinger, K.5
Cho, J.H.6
-
12
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
E. Bettelli, Y. Carrier, W. Gao, T. Korn, T.B. Strom, and M. Oukka Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells Nature 441 2006 235 238
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
-
13
-
-
45749101727
-
Induction and effector functions of T (H)17 cells
-
E. Bettelli, T. Korn, M. Oukka, and V.K. Kuchroo Induction and effector functions of T (H)17 cells Nature 453 2008 1051 1057
-
(2008)
Nature
, vol.453
, pp. 1051-1057
-
-
Bettelli, E.1
Korn, T.2
Oukka, M.3
Kuchroo, V.K.4
-
14
-
-
0032538915
-
Oxazolone colitis: A murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4
-
M. Boirivant, I.J. Fuss, A. Chu, and W. Strober Oxazolone colitis: A murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4 J Exp Med 188 1998 1929 1939
-
(1998)
J Exp Med
, vol.188
, pp. 1929-1939
-
-
Boirivant, M.1
Fuss, I.J.2
Chu, A.3
Strober, W.4
-
15
-
-
0032768352
-
Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease
-
J. Boudeau, A.L. Glasser, E. Masseret, B. Joly, and A. Darfeuille-Michaud Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn's disease Infect Immun 67 1999 4499 4509
-
(1999)
Infect Immun
, vol.67
, pp. 4499-4509
-
-
Boudeau, J.1
Glasser, A.L.2
Masseret, E.3
Joly, B.4
Darfeuille-Michaud, A.5
-
16
-
-
77951878587
-
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
-
S. Buonocore, P.P. Ahern, H.H. Uhlig, I.I. Ivanov, D.R. Littman, and K.J. Maloy Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology Nature 464 2010 1371 1375
-
(2010)
Nature
, vol.464
, pp. 1371-1375
-
-
Buonocore, S.1
Ahern, P.P.2
Uhlig, H.H.3
Ivanov, I.I.4
Littman, D.R.5
Maloy, K.J.6
-
17
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
K. Cadwell, J.Y. Liu, S.L. Brown, H. Miyoshi, J. Loh, and J.K. Lennerz A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells Nature 456 2008 259 263
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
Miyoshi, H.4
Loh, J.5
Lennerz, J.K.6
-
18
-
-
77953904042
-
Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine
-
K. Cadwell, K.K. Patel, N.S. Maloney, T.C. Liu, A.C. Ng, and C.E. Storer Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine Cell 141 2010 1135 1145
-
(2010)
Cell
, vol.141
, pp. 1135-1145
-
-
Cadwell, K.1
Patel, K.K.2
Maloney, N.S.3
Liu, T.C.4
Ng, A.C.5
Storer, C.E.6
-
19
-
-
34247235029
-
Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function
-
E. Cario, G. Gerken, and D.K. Podolsky Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function Gastroenterology 132 2007 1359 1374
-
(2007)
Gastroenterology
, vol.132
, pp. 1359-1374
-
-
Cario, E.1
Gerken, G.2
Podolsky, D.K.3
-
20
-
-
0028290252
-
Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse
-
M.G. Cecchini, M.G. Dominguez, S. Mocci, A. Wetterwald, R. Felix, and H. Fleisch Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse Development 120 1994 1357 1372
-
(1994)
Development
, vol.120
, pp. 1357-1372
-
-
Cecchini, M.G.1
Dominguez, M.G.2
Mocci, S.3
Wetterwald, A.4
Felix, R.5
Fleisch, H.6
-
21
-
-
59649099774
-
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
-
M. Cella, A. Fuchs, W. Vermi, F. Facchetti, K. Otero, and J.K. Lennerz A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity Nature 457 2009 722 725
-
(2009)
Nature
, vol.457
, pp. 722-725
-
-
Cella, M.1
Fuchs, A.2
Vermi, W.3
Facchetti, F.4
Otero, K.5
Lennerz, J.K.6
-
22
-
-
79952230127
-
Crohn disease - Associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae
-
B. Chassaing, N. Rolhion, A. de Vallee, S.Y. Salim, M. Prorok-Hamon, and C. Neut Crohn disease - associated adherent-invasive E. coli bacteria target mouse and human Peyer's patches via long polar fimbriae J Clin Invest 121 2011 966 975
-
(2011)
J Clin Invest
, vol.121
, pp. 966-975
-
-
Chassaing, B.1
Rolhion, N.2
De Vallee, A.3
Salim, S.Y.4
Prorok-Hamon, M.5
Neut, C.6
-
23
-
-
34547538202
-
Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells
-
H. Chinen, K. Matsuoka, T. Sato, N. Kamada, S. Okamoto, and T. Hisamatsu Lamina propria c-kit+ immune precursors reside in human adult intestine and differentiate into natural killer cells Gastroenterology 133 2007 559 573
-
(2007)
Gastroenterology
, vol.133
, pp. 559-573
-
-
Chinen, H.1
Matsuoka, K.2
Sato, T.3
Kamada, N.4
Okamoto, S.5
Hisamatsu, T.6
-
24
-
-
44349124113
-
The genetics and immunopathogenesis of inflammatory bowel disease
-
J.H. Cho The genetics and immunopathogenesis of inflammatory bowel disease Nat Rev Immunol 8 2008 458 466
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 458-466
-
-
Cho, J.H.1
-
25
-
-
33846242958
-
Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial
-
J.F. Colombel, W.J. Sandborn, P. Rutgeerts, R. Enns, S.B. Hanauer, and R. Panaccione Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial Gastroenterology 132 2007 52 65
-
(2007)
Gastroenterology
, vol.132
, pp. 52-65
-
-
Colombel, J.F.1
Sandborn, W.J.2
Rutgeerts, P.3
Enns, R.4
Hanauer, S.B.5
Panaccione, R.6
-
26
-
-
68249137286
-
Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity
-
M. Colonna Interleukin-22-producing natural killer cells and lymphoid tissue inducer-like cells in mucosal immunity Immunity 31 2009 15 23
-
(2009)
Immunity
, vol.31
, pp. 15-23
-
-
Colonna, M.1
-
27
-
-
33845454742
-
Gut-associated bacterial microbiota in paediatric patients with inflammatory bowel disease
-
M.P. Conte, S. Schippa, I. Zamboni, M. Penta, F. Chiarini, and L. Seganti Gut-associated bacterial microbiota in paediatric patients with inflammatory bowel disease Gut 55 2006 1760 1767
-
(2006)
Gut
, vol.55
, pp. 1760-1767
-
-
Conte, M.P.1
Schippa, S.2
Zamboni, I.3
Penta, M.4
Chiarini, F.5
Seganti, L.6
-
28
-
-
77954143695
-
Innate IL-17-producing cells: The sentinels of the immune system
-
D.J. Cua, and C.M. Tato Innate IL-17-producing cells: The sentinels of the immune system Nat Rev Immunol 10 2010 479 489
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 479-489
-
-
Cua, D.J.1
Tato, C.M.2
-
29
-
-
57849131584
-
Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+CD127+natural killer-like cells
-
T. Cupedo, N.K. Crellin, N. Papazian, E.J. Rombouts, K. Weijer, and J.L. Grogan Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+CD127+natural killer-like cells Nat Immunol 10 2009 66 74
-
(2009)
Nat Immunol
, vol.10
, pp. 66-74
-
-
Cupedo, T.1
Crellin, N.K.2
Papazian, N.3
Rombouts, E.J.4
Weijer, K.5
Grogan, J.L.6
-
30
-
-
4143069158
-
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease
-
A. Darfeuille-Michaud, J. Boudeau, P. Bulois, C. Neut, A.L. Glasser, and N. Barnich High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease Gastroenterology 127 2004 412 421
-
(2004)
Gastroenterology
, vol.127
, pp. 412-421
-
-
Darfeuille-Michaud, A.1
Boudeau, J.2
Bulois, P.3
Neut, C.4
Glasser, A.L.5
Barnich, N.6
-
31
-
-
0031758230
-
Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease
-
A. Darfeuille-Michaud, C. Neut, N. Barnich, E. Lederman, P. Di Martino, and P. Desreumaux Presence of adherent Escherichia coli strains in ileal mucosa of patients with Crohn's disease Gastroenterology 115 1998 1405 1413
-
(1998)
Gastroenterology
, vol.115
, pp. 1405-1413
-
-
Darfeuille-Michaud, A.1
Neut, C.2
Barnich, N.3
Lederman, E.4
Di Martino, P.5
Desreumaux, P.6
-
32
-
-
34548764423
-
Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses
-
T.L. Denning, Y.C. Wang, S.R. Patel, I.R. Williams, and B. Pulendran Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses Nat Immunol 8 2007 1086 1094
-
(2007)
Nat Immunol
, vol.8
, pp. 1086-1094
-
-
Denning, T.L.1
Wang, Y.C.2
Patel, S.R.3
Williams, I.R.4
Pulendran, B.5
-
33
-
-
0027231774
-
Tumour-necrosis-factor antibody treatment in Crohn's disease
-
B. Derkx, J. Taminiau, S. Radema, A. Stronkhorst, C. Wortel, and G. Tytgat Tumour-necrosis-factor antibody treatment in Crohn's disease Lancet 342 1993 173 174
-
(1993)
Lancet
, vol.342
, pp. 173-174
-
-
Derkx, B.1
Taminiau, J.2
Radema, S.3
Stronkhorst, A.4
Wortel, C.5
Tytgat, G.6
-
34
-
-
84863436944
-
Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice
-
S. Devkota, Y. Wang, M.W. Musch, V. Leone, H. Fehlner-Peach, and A. Nadimpalli Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice Nature 487 2012 104 108
-
(2012)
Nature
, vol.487
, pp. 104-108
-
-
Devkota, S.1
Wang, Y.2
Musch, M.W.3
Leone, V.4
Fehlner-Peach, H.5
Nadimpalli, A.6
-
36
-
-
3042720708
-
Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+cells
-
G. Eberl, and D.R. Littman Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+cells Science 305 2004 248 251
-
(2004)
Science
, vol.305
, pp. 248-251
-
-
Eberl, G.1
Littman, D.R.2
-
37
-
-
0346496018
-
An essential function for the nuclear receptor RORgamma (t) in the generation of fetal lymphoid tissue inducer cells
-
G. Eberl, S. Marmon, M.J. Sunshine, P.D. Rennert, Y. Choi, and D.R. Littman An essential function for the nuclear receptor RORgamma (t) in the generation of fetal lymphoid tissue inducer cells Nat Immunol 5 2004 64 73
-
(2004)
Nat Immunol
, vol.5
, pp. 64-73
-
-
Eberl, G.1
Marmon, S.2
Sunshine, M.J.3
Rennert, P.D.4
Choi, Y.5
Littman, D.R.6
-
38
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
E. Elinav, T. Strowig, A.L. Kau, J. Henao-Mejia, C.A. Thaiss, and C.J. Booth NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis Cell 145 2011 745 757
-
(2011)
Cell
, vol.145
, pp. 745-757
-
-
Elinav, E.1
Strowig, T.2
Kau, A.L.3
Henao-Mejia, J.4
Thaiss, C.A.5
Booth, C.J.6
-
39
-
-
34250026960
-
Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice
-
C.O. Elson, Y. Cong, C.T. Weaver, T.R. Schoeb, T.K. McClanahan, and R.B. Fick Monoclonal anti-interleukin 23 reverses active colitis in a T cell-mediated model in mice Gastroenterology 132 2007 2359 2370
-
(2007)
Gastroenterology
, vol.132
, pp. 2359-2370
-
-
Elson, C.O.1
Cong, Y.2
Weaver, C.T.3
Schoeb, T.R.4
McClanahan, T.K.5
Fick, R.B.6
-
40
-
-
36549074568
-
Health-related quality of life during natalizumab maintenance therapy for Crohn's disease
-
B.G. Feagan, W.J. Sandborn, S. Hass, T. Niecko, and J. White Health-related quality of life during natalizumab maintenance therapy for Crohn's disease Am J Gastroenterol 102 2007 2737 2746
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 2737-2746
-
-
Feagan, B.G.1
Sandborn, W.J.2
Hass, S.3
Niecko, T.4
White, J.5
-
41
-
-
78650099360
-
Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases
-
D.N. Frank, C.E. Robertson, C.M. Hamm, Z. Kpadeh, T. Zhang, and H. Chen Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseases Inflamm Bowel Dis 17 2011 179 184
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 179-184
-
-
Frank, D.N.1
Robertson, C.E.2
Hamm, C.M.3
Kpadeh, Z.4
Zhang, T.5
Chen, H.6
-
42
-
-
35348857386
-
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
-
D.N. Frank, A.L. St Amand, R.A. Feldman, E.C. Boedeker, N. Harpaz, and N.R. Pace Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases Proc Natl Acad Sci U S A 104 2007 13780 13785
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 13780-13785
-
-
Frank, D.N.1
St Amand, A.L.2
Feldman, R.A.3
Boedeker, E.C.4
Harpaz, N.5
Pace, N.R.6
-
43
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
A. Franke, D.P. McGovern, J.C. Barrett, K. Wang, G.L. Radford-Smith, and T. Ahmad Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci Nat Genet 42 2010 1118 1125
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
Wang, K.4
Radford-Smith, G.L.5
Ahmad, T.6
-
44
-
-
59749098334
-
FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+T cells in bone marrow
-
T. Fujii, T. Tomita, T. Kanai, Y. Nemoto, T. Totsuka, and N. Sakamoto FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+T cells in bone marrow Eur J Immunol 38 2008 3290 3303
-
(2008)
Eur J Immunol
, vol.38
, pp. 3290-3303
-
-
Fujii, T.1
Tomita, T.2
Kanai, T.3
Nemoto, Y.4
Totsuka, T.5
Sakamoto, N.6
-
45
-
-
0037216498
-
Increased expression of interleukin 17 in inflammatory bowel disease
-
S. Fujino, A. Andoh, S. Bamba, A. Ogawa, K. Hata, and Y. Araki Increased expression of interleukin 17 in inflammatory bowel disease Gut 52 2003 65 70
-
(2003)
Gut
, vol.52
, pp. 65-70
-
-
Fujino, S.1
Andoh, A.2
Bamba, S.3
Ogawa, A.4
Hata, K.5
Araki, Y.6
-
46
-
-
70450248450
-
Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: Analysis of the organization of the Atg16L1 complex in fibroblasts
-
N. Fujita, T. Saitoh, S. Kageyama, S. Akira, T. Noda, and T. Yoshimori Differential involvement of Atg16L1 in Crohn disease and canonical autophagy: Analysis of the organization of the Atg16L1 complex in fibroblasts J Biol Chem 284 2009 32602 32609
-
(2009)
J Biol Chem
, vol.284
, pp. 32602-32609
-
-
Fujita, N.1
Saitoh, T.2
Kageyama, S.3
Akira, S.4
Noda, T.5
Yoshimori, T.6
-
47
-
-
85047690640
-
Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis
-
I.J. Fuss, F. Heller, M. Boirivant, F. Leon, M. Yoshida, and S. Fichtner-Feigl Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis J Clin Invest 113 2004 1490 1497
-
(2004)
J Clin Invest
, vol.113
, pp. 1490-1497
-
-
Fuss, I.J.1
Heller, F.2
Boirivant, M.3
Leon, F.4
Yoshida, M.5
Fichtner-Feigl, S.6
-
48
-
-
34848889673
-
Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
-
W.S. Garrett, G.M. Lord, S. Punit, G. Lugo-Villarino, S.K. Mazmanian, and S. Ito Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system Cell 131 2007 33 45
-
(2007)
Cell
, vol.131
, pp. 33-45
-
-
Garrett, W.S.1
Lord, G.M.2
Punit, S.3
Lugo-Villarino, G.4
Mazmanian, S.K.5
Ito, S.6
-
49
-
-
79958277385
-
IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease
-
A. Geremia, C.V. Arancibia-Carcamo, M.P. Fleming, N. Rust, B. Singh, and N.J. Mortensen IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease J Exp Med 208 2011 1127 1133
-
(2011)
J Exp Med
, vol.208
, pp. 1127-1133
-
-
Geremia, A.1
Arancibia-Carcamo, C.V.2
Fleming, M.P.3
Rust, N.4
Singh, B.5
Mortensen, N.J.6
-
50
-
-
77958584113
-
Generation of pathogenic T (H) 17 cells in the absence of TGF-beta signalling
-
K. Ghoreschi, A. Laurence, X.P. Yang, C.M. Tato, M.J. McGeachy, and J.E. Konkel Generation of pathogenic T (H) 17 cells in the absence of TGF-beta signalling Nature 467 2010 967 971
-
(2010)
Nature
, vol.467
, pp. 967-971
-
-
Ghoreschi, K.1
Laurence, A.2
Yang, X.P.3
Tato, C.M.4
McGeachy, M.J.5
Konkel, J.E.6
-
51
-
-
77958003426
-
Infant colitis-it's in the genes
-
E.O. Glocker, N. Frede, M. Perro, N. Sebire, M. Elawad, and N. Shah Infant colitis-it's in the genes Lancet 376 2010 1272
-
(2010)
Lancet
, vol.376
, pp. 1272
-
-
Glocker, E.O.1
Frede, N.2
Perro, M.3
Sebire, N.4
Elawad, M.5
Shah, N.6
-
52
-
-
70949087383
-
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor
-
E.O. Glocker, D. Kotlarz, K. Boztug, E.M. Gertz, A.A. Schaffer, and F. Noyan Inflammatory bowel disease and mutations affecting the interleukin-10 receptor N Engl J Med 361 2009 2033 2045
-
(2009)
N Engl J Med
, vol.361
, pp. 2033-2045
-
-
Glocker, E.O.1
Kotlarz, D.2
Boztug, K.3
Gertz, E.M.4
Schaffer, A.A.5
Noyan, F.6
-
53
-
-
36749004359
-
Exacerbation of ulcerative colitis after rituximab salvage therapy
-
M. Goetz, R. Atreya, M. Ghalibafian, P.R. Galle, and M.F. Neurath Exacerbation of ulcerative colitis after rituximab salvage therapy Inflamm Bowel Dis 13 2007 1365 1368
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 1365-1368
-
-
Goetz, M.1
Atreya, R.2
Ghalibafian, M.3
Galle, P.R.4
Neurath, M.F.5
-
54
-
-
79955025122
-
Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice
-
A.L. Goodman, G. Kallstrom, J.J. Faith, A. Reyes, A. Moore, and G. Dantas Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice Proc Natl Acad Sci U S A 108 2011 6252 6257
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 6252-6257
-
-
Goodman, A.L.1
Kallstrom, G.2
Faith, J.J.3
Reyes, A.4
Moore, A.5
Dantas, G.6
-
55
-
-
28544446111
-
Monocyte and macrophage heterogeneity
-
S. Gordon, and P.R. Taylor Monocyte and macrophage heterogeneity Nat Rev Immunol 5 2005 953 964
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 953-964
-
-
Gordon, S.1
Taylor, P.R.2
-
56
-
-
80052845560
-
Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis
-
C. Gunther, E. Martini, N. Wittkopf, K. Amann, B. Weigmann, and H. Neumann Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis Nature 477 2011 335 339
-
(2011)
Nature
, vol.477
, pp. 335-339
-
-
Gunther, C.1
Martini, E.2
Wittkopf, N.3
Amann, K.4
Weigmann, B.5
Neumann, H.6
-
57
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
J. Hampe, A. Franke, P. Rosenstiel, A. Till, M. Teuber, and K. Huse A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 Nat Genet 39 2007 207 211
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
-
58
-
-
0037018761
-
Maintenance infliximab for Crohn's disease: The ACCENT i randomised trial
-
S.B. Hanauer, B.G. Feagan, G.R. Lichtenstein, L.F. Mayer, S. Schreiber, and J.F. Colombel Maintenance infliximab for Crohn's disease: The ACCENT I randomised trial Lancet 359 2002 1541 1549
-
(2002)
Lancet
, vol.359
, pp. 1541-1549
-
-
Hanauer, S.B.1
Feagan, B.G.2
Lichtenstein, G.R.3
Mayer, L.F.4
Schreiber, S.5
Colombel, J.F.6
-
59
-
-
0038382993
-
The state of the art in the management of inflammatory bowel disease
-
S.B. Hanauer, and D.H. Present The state of the art in the management of inflammatory bowel disease Rev Gastroenterol Disord 3 2003 81 92
-
(2003)
Rev Gastroenterol Disord
, vol.3
, pp. 81-92
-
-
Hanauer, S.B.1
Present, D.H.2
-
60
-
-
32044451548
-
Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLASSIC-I trial
-
(quiz 591)
-
S.B. Hanauer, W.J. Sandborn, P. Rutgeerts, R.N. Fedorak, M. Lukas, and D. MacIntosh Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLASSIC-I trial Gastroenterology 130 2006 323 333 (quiz 591)
-
(2006)
Gastroenterology
, vol.130
, pp. 323-333
-
-
Hanauer, S.B.1
Sandborn, W.J.2
Rutgeerts, P.3
Fedorak, R.N.4
Lukas, M.5
MacIntosh, D.6
-
61
-
-
0036850908
-
Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells
-
F. Heller, I.J. Fuss, E.E. Nieuwenhuis, R.S. Blumberg, and W. Strober Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells Immunity 17 2002 629 638
-
(2002)
Immunity
, vol.17
, pp. 629-638
-
-
Heller, F.1
Fuss, I.J.2
Nieuwenhuis, E.E.3
Blumberg, R.S.4
Strober, W.5
-
62
-
-
14844344042
-
The nuclear IkappaB protein IkappaBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria
-
T. Hirotani, P.Y. Lee, H. Kuwata, M. Yamamoto, M. Matsumoto, and I. Kawase The nuclear IkappaB protein IkappaBNS selectively inhibits lipopolysaccharide-induced IL-6 production in macrophages of the colonic lamina propria J Immunol 174 2005 3650 3657
-
(2005)
J Immunol
, vol.174
, pp. 3650-3657
-
-
Hirotani, T.1
Lee, P.Y.2
Kuwata, H.3
Yamamoto, M.4
Matsumoto, M.5
Kawase, I.6
-
63
-
-
84856420259
-
Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease
-
T. Hisamatsu, S. Okamoto, M. Hashimoto, T. Muramatsu, A. Andou, and M. Uo Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease PLoS One 7 2012 e31131
-
(2012)
PLoS One
, vol.7
, pp. 31131
-
-
Hisamatsu, T.1
Okamoto, S.2
Hashimoto, M.3
Muramatsu, T.4
Andou, A.5
Uo, M.6
-
64
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
J.P. Hugot, M. Chamaillard, H. Zouali, S. Lesage, J.P. Cezard, and J. Belaiche Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease Nature 411 2001 599 603
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
-
65
-
-
0034655214
-
Suppression of endogenous IL-10 gene expression in dendritic cells enhances antigen presentation for specific Th1 induction: Potential for cellular vaccine development
-
J.U. Igietseme, G.A. Ananaba, J. Bolier, S. Bowers, T. Moore, and T. Belay Suppression of endogenous IL-10 gene expression in dendritic cells enhances antigen presentation for specific Th1 induction: Potential for cellular vaccine development J Immunol 164 2000 4212 4219
-
(2000)
J Immunol
, vol.164
, pp. 4212-4219
-
-
Igietseme, J.U.1
Ananaba, G.A.2
Bolier, J.3
Bowers, S.4
Moore, T.5
Belay, T.6
-
66
-
-
84861964286
-
Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis
-
I.D. Iliev, V.A. Funari, K.D. Taylor, Q. Nguyen, C.N. Reyes, and S.P. Strom Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis Science 336 2012 1314 1317
-
(2012)
Science
, vol.336
, pp. 1314-1317
-
-
Iliev, I.D.1
Funari, V.A.2
Taylor, K.D.3
Nguyen, Q.4
Reyes, C.N.5
Strom, S.P.6
-
67
-
-
0036306951
-
Lack of common NOD2 variants in Japanese patients with Crohn's disease
-
N. Inoue, K. Tamura, Y. Kinouchi, Y. Fukuda, S. Takahashi, and Y. Ogura Lack of common NOD2 variants in Japanese patients with Crohn's disease Gastroenterology 123 2002 86 91
-
(2002)
Gastroenterology
, vol.123
, pp. 86-91
-
-
Inoue, N.1
Tamura, K.2
Kinouchi, Y.3
Fukuda, Y.4
Takahashi, S.5
Ogura, Y.6
-
68
-
-
70350343544
-
Induction of intestinal Th17 cells by segmented filamentous bacteria
-
I.I. Ivanov, K. Atarashi, N. Manel, E.L. Brodie, T. Shima, and U. Karaoz Induction of intestinal Th17 cells by segmented filamentous bacteria Cell 139 2009 485 498
-
(2009)
Cell
, vol.139
, pp. 485-498
-
-
Ivanov, I.I.1
Atarashi, K.2
Manel, N.3
Brodie, E.L.4
Shima, T.5
Karaoz, U.6
-
69
-
-
68149183243
-
Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability
-
N. Kamada, T. Hisamatsu, H. Honda, T. Kobayashi, H. Chinen, and M.T. Kitazume Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability J Immunol 183 2009 1724 1731
-
(2009)
J Immunol
, vol.183
, pp. 1724-1731
-
-
Kamada, N.1
Hisamatsu, T.2
Honda, H.3
Kobayashi, T.4
Chinen, H.5
Kitazume, M.T.6
-
70
-
-
77949514515
-
TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease
-
N. Kamada, T. Hisamatsu, H. Honda, T. Kobayashi, H. Chinen, and T. Takayama TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease Inflamm Bowel Dis 16 2010 568 575
-
(2010)
Inflamm Bowel Dis
, vol.16
, pp. 568-575
-
-
Kamada, N.1
Hisamatsu, T.2
Honda, H.3
Kobayashi, T.4
Chinen, H.5
Takayama, T.6
-
71
-
-
45749107055
-
Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis
-
N. Kamada, T. Hisamatsu, S. Okamoto, H. Chinen, T. Kobayashi, and T. Sato Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis J Clin Invest 118 2008 2269 2280
-
(2008)
J Clin Invest
, vol.118
, pp. 2269-2280
-
-
Kamada, N.1
Hisamatsu, T.2
Okamoto, S.3
Chinen, H.4
Kobayashi, T.5
Sato, T.6
-
72
-
-
27744437941
-
Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria
-
N. Kamada, T. Hisamatsu, S. Okamoto, T. Sato, K. Matsuoka, and K. Arai Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria J Immunol 175 2005 6900 6908
-
(2005)
J Immunol
, vol.175
, pp. 6900-6908
-
-
Kamada, N.1
Hisamatsu, T.2
Okamoto, S.3
Sato, T.4
Matsuoka, K.5
Arai, K.6
-
73
-
-
0034800289
-
Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease
-
T. Kanai, M. Watanabe, A. Okazawa, T. Sato, M. Yamazaki, and S. Okamoto Macrophage-derived IL-18-mediated intestinal inflammation in the murine model of Crohn's disease Gastroenterology 121 2001 875 888
-
(2001)
Gastroenterology
, vol.121
, pp. 875-888
-
-
Kanai, T.1
Watanabe, M.2
Okazawa, A.3
Sato, T.4
Yamazaki, M.5
Okamoto, S.6
-
74
-
-
50249086073
-
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
-
A. Kaser, A.H. Lee, A. Franke, J.N. Glickman, S. Zeissig, and H. Tilg XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease Cell 134 2008 743 756
-
(2008)
Cell
, vol.134
, pp. 743-756
-
-
Kaser, A.1
Lee, A.H.2
Franke, A.3
Glickman, J.N.4
Zeissig, S.5
Tilg, H.6
-
75
-
-
33745743021
-
IL-13 receptor alpha2 promotes epithelial cell regeneration from radiation-induced small intestinal injury in mice
-
R. Kawashima, Y.I. Kawamura, R. Kato, N. Mizutani, N. Toyama-Sorimachi, and T. Dohi IL-13 receptor alpha2 promotes epithelial cell regeneration from radiation-induced small intestinal injury in mice Gastroenterology 131 2006 130 141
-
(2006)
Gastroenterology
, vol.131
, pp. 130-141
-
-
Kawashima, R.1
Kawamura, Y.I.2
Kato, R.3
Mizutani, N.4
Toyama-Sorimachi, N.5
Dohi, T.6
-
76
-
-
81855228077
-
Interleukin-13 damages intestinal mucosa via TWEAK and Fn14 in mice-a pathway associated with ulcerative colitis
-
R. Kawashima, Y.I. Kawamura, T. Oshio, A. Son, M. Yamazaki, and T. Hagiwara Interleukin-13 damages intestinal mucosa via TWEAK and Fn14 in mice-a pathway associated with ulcerative colitis Gastroenterology 141 2119-2129 2011 e2118
-
(2011)
Gastroenterology
, vol.141
, Issue.2119-2129
, pp. 2118
-
-
Kawashima, R.1
Kawamura, Y.I.2
Oshio, T.3
Son, A.4
Yamazaki, M.5
Hagiwara, T.6
-
77
-
-
84865739557
-
Microbiota separation and C-reactive protein elevation in treatment naive pediatric granulomatous Crohn disease
-
R. Kellermayer, S.A. Mir, D. Nagy-Szakal, S.B. Cox, S.E. Dowd, and J.L. Kaplan Microbiota separation and C-reactive protein elevation in treatment naive pediatric granulomatous Crohn disease J Pediatr Gastroenterol Nutr 55 2012 243 250
-
(2012)
J Pediatr Gastroenterol Nutr
, vol.55
, pp. 243-250
-
-
Kellermayer, R.1
Mir, S.A.2
Nagy-Szakal, D.3
Cox, S.B.4
Dowd, S.E.5
Kaplan, J.L.6
-
78
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
K.S. Kobayashi, M. Chamaillard, Y. Ogura, O. Henegariu, N. Inohara, and G. Nunez Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract Science 307 2005 731 734
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
Nunez, G.6
-
79
-
-
78651322066
-
Rapid endoscopic improvement is important for 1-year avoidance of colectomy but not for the long-term prognosis in cyclosporine A treatment for ulcerative colitis
-
T. Kobayashi, M. Naganuma, S. Okamoto, T. Hisamatsu, N. Inoue, and H. Ichikawa Rapid endoscopic improvement is important for 1-year avoidance of colectomy but not for the long-term prognosis in cyclosporine A treatment for ulcerative colitis J Gastroenterol 45 2010 1129 1137
-
(2010)
J Gastroenterol
, vol.45
, pp. 1129-1137
-
-
Kobayashi, T.1
Naganuma, M.2
Okamoto, S.3
Hisamatsu, T.4
Inoue, N.5
Ichikawa, H.6
-
80
-
-
56549104968
-
IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease
-
T. Kobayashi, S. Okamoto, T. Hisamatsu, N. Kamada, H. Chinen, and R. Saito IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease Gut 57 2008 1682 1689
-
(2008)
Gut
, vol.57
, pp. 1682-1689
-
-
Kobayashi, T.1
Okamoto, S.2
Hisamatsu, T.3
Kamada, N.4
Chinen, H.5
Saito, R.6
-
81
-
-
84864206050
-
Loss of interleukin-10 signaling and infantile inflammatory bowel disease: Implications for diagnosis and therapy
-
D. Kotlarz, R. Beier, D. Murugan, J. Diestelhorst, O. Jensen, and K. Boztug Loss of interleukin-10 signaling and infantile inflammatory bowel disease: Implications for diagnosis and therapy Gastroenterology 143 2012 347 355
-
(2012)
Gastroenterology
, vol.143
, pp. 347-355
-
-
Kotlarz, D.1
Beier, R.2
Murugan, D.3
Diestelhorst, J.4
Jensen, O.5
Boztug, K.6
-
82
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
R. Kuhn, J. Lohler, D. Rennick, K. Rajewsky, and W. Muller Interleukin-10-deficient mice develop chronic enterocolitis Cell 75 1993 263 274
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
83
-
-
58149251898
-
Late developmental plasticity in the T helper 17 lineage
-
Y.K. Lee, H. Turner, C.L. Maynard, J.R. Oliver, D. Chen, and C.O. Elson Late developmental plasticity in the T helper 17 lineage Immunity 30 2009 92 107
-
(2009)
Immunity
, vol.30
, pp. 92-107
-
-
Lee, Y.K.1
Turner, H.2
Maynard, C.L.3
Oliver, J.R.4
Chen, D.5
Elson, C.O.6
-
84
-
-
80053566144
-
Randomised placebo-controlled trial of rituximab (anti-CD20) in active ulcerative colitis
-
K. Leiper, K. Martin, A. Ellis, S. Subramanian, A.J. Watson, and S.E. Christmas Randomised placebo-controlled trial of rituximab (anti-CD20) in active ulcerative colitis Gut 60 2011 1520 1526
-
(2011)
Gut
, vol.60
, pp. 1520-1526
-
-
Leiper, K.1
Martin, K.2
Ellis, A.3
Subramanian, S.4
Watson, A.J.5
Christmas, S.E.6
-
85
-
-
59849114998
-
RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F
-
M. Leppkes, C. Becker, I.I. Ivanov, S. Hirth, S. Wirtz, and C. Neufert RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F Gastroenterology 136 2009 257 267
-
(2009)
Gastroenterology
, vol.136
, pp. 257-267
-
-
Leppkes, M.1
Becker, C.2
Ivanov, I.I.3
Hirth, S.4
Wirtz, S.5
Neufert, C.6
-
86
-
-
84861001724
-
Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition
-
E. Li, C.M. Hamm, A.S. Gulati, R.B. Sartor, H. Chen, and X. Wu Inflammatory bowel diseases phenotype, C. difficile and NOD2 genotype are associated with shifts in human ileum associated microbial composition PLoS One 7 2012 e26284
-
(2012)
PLoS One
, vol.7
, pp. 26284
-
-
Li, E.1
Hamm, C.M.2
Gulati, A.S.3
Sartor, R.B.4
Chen, H.5
Wu, X.6
-
87
-
-
0028292007
-
Cyclosporine in severe ulcerative colitis refractory to steroid therapy
-
S. Lichtiger, D.H. Present, A. Kornbluth, I. Gelernt, J. Bauer, and G. Galler Cyclosporine in severe ulcerative colitis refractory to steroid therapy N Engl J Med 330 1994 1841 1845
-
(1994)
N Engl J Med
, vol.330
, pp. 1841-1845
-
-
Lichtiger, S.1
Present, D.H.2
Kornbluth, A.3
Gelernt, I.4
Bauer, J.5
Galler, G.6
-
88
-
-
44049104564
-
The differentiation of human T (H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
-
N. Manel, D. Unutmaz, and D.R. Littman The differentiation of human T (H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat Nat Immunol 9 2008 641 649
-
(2008)
Nat Immunol
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
89
-
-
33646560950
-
Transforming growth factor-beta induces development of the T (H) 17 lineage
-
P.R. Mangan, L.E. Harrington, D.B. O'Quinn, W.S. Helms, D.C. Bullard, and C.O. Elson Transforming growth factor-beta induces development of the T (H) 17 lineage Nature 441 2006 231 234
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
-
90
-
-
8344284998
-
Anti-interleukin-12 antibody for active Crohn's disease
-
P.J. Mannon, I.J. Fuss, L. Mayer, C.O. Elson, W.J. Sandborn, and D. Present Anti-interleukin-12 antibody for active Crohn's disease N Engl J Med 351 2004 2069 2079
-
(2004)
N Engl J Med
, vol.351
, pp. 2069-2079
-
-
Mannon, P.J.1
Fuss, I.J.2
Mayer, L.3
Elson, C.O.4
Sandborn, W.J.5
Present, D.6
-
91
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
A. Mantovani, A. Sica, S. Sozzani, P. Allavena, A. Vecchi, and M. Locati The chemokine system in diverse forms of macrophage activation and polarization Trends Immunol 25 2004 677 686
-
(2004)
Trends Immunol
, vol.25
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
Allavena, P.4
Vecchi, A.5
Locati, M.6
-
92
-
-
3242737791
-
Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer
-
H.M. Martin, B.J. Campbell, C.A. Hart, C. Mpofu, M. Nayar, and R. Singh Enhanced Escherichia coli adherence and invasion in Crohn's disease and colon cancer Gastroenterology 127 2004 80 93
-
(2004)
Gastroenterology
, vol.127
, pp. 80-93
-
-
Martin, H.M.1
Campbell, B.J.2
Hart, C.A.3
Mpofu, C.4
Nayar, M.5
Singh, R.6
-
93
-
-
40949145305
-
Unstable composition of the fecal microbiota in ulcerative colitis during clinical remission
-
C. Martinez, M. Antolin, J. Santos, A. Torrejon, F. Casellas, and N. Borruel Unstable composition of the fecal microbiota in ulcerative colitis during clinical remission Am J Gastroenterol 103 2008 643 648
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 643-648
-
-
Martinez, C.1
Antolin, M.2
Santos, J.3
Torrejon, A.4
Casellas, F.5
Borruel, N.6
-
94
-
-
67649509224
-
Molecular diversity of Escherichia coli in the human gut: New ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease
-
M. Martinez-Medina, X. Aldeguer, M. Lopez-Siles, F. Gonzalez-Huix, C. Lopez-Oliu, and G. Dahbi Molecular diversity of Escherichia coli in the human gut: New ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohn's disease Inflamm Bowel Dis 15 2009 872 882
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 872-882
-
-
Martinez-Medina, M.1
Aldeguer, X.2
Lopez-Siles, M.3
Gonzalez-Huix, F.4
Lopez-Oliu, C.5
Dahbi, G.6
-
95
-
-
4344591762
-
T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease
-
K. Matsuoka, N. Inoue, T. Sato, S. Okamoto, T. Hisamatsu, and Y. Kishi T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease Gut 53 2004 1303 1308
-
(2004)
Gut
, vol.53
, pp. 1303-1308
-
-
Matsuoka, K.1
Inoue, N.2
Sato, T.3
Okamoto, S.4
Hisamatsu, T.5
Kishi, Y.6
-
96
-
-
44449106055
-
A microbial symbiosis factor prevents intestinal inflammatory disease
-
S.K. Mazmanian, J.L. Round, and D.L. Kasper A microbial symbiosis factor prevents intestinal inflammatory disease Nature 453 2008 620 625
-
(2008)
Nature
, vol.453
, pp. 620-625
-
-
Mazmanian, S.K.1
Round, J.L.2
Kasper, D.L.3
-
97
-
-
36248965294
-
TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T (H)-17 cell-mediated pathology
-
M.J. McGeachy, K.S. Bak-Jensen, Y. Chen, C.M. Tato, W. Blumenschein, and T. McClanahan TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T (H)-17 cell-mediated pathology Nat Immunol 8 2007 1390 1397
-
(2007)
Nat Immunol
, vol.8
, pp. 1390-1397
-
-
McGeachy, M.J.1
Bak-Jensen, K.S.2
Chen, Y.3
Tato, C.M.4
Blumenschein, W.5
McClanahan, T.6
-
98
-
-
77950298959
-
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
-
D.P. McGovern, A. Gardet, L. Torkvist, P. Goyette, J. Essers, and K.D. Taylor Genome-wide association identifies multiple ulcerative colitis susceptibility loci Nat Genet 42 2010 332 337
-
(2010)
Nat Genet
, vol.42
, pp. 332-337
-
-
McGovern, D.P.1
Gardet, A.2
Torkvist, L.3
Goyette, P.4
Essers, J.5
Taylor, K.D.6
-
99
-
-
0030710079
-
Developing lymph nodes collect CD4+CD3- LTbeta+cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells
-
R.E. Mebius, P. Rennert, and I.L. Weissman Developing lymph nodes collect CD4+CD3- LTbeta+cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells Immunity 7 1997 493 504
-
(1997)
Immunity
, vol.7
, pp. 493-504
-
-
Mebius, R.E.1
Rennert, P.2
Weissman, I.L.3
-
100
-
-
77956456087
-
Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis
-
Y. Mikami, T. Kanai, T. Sujino, Y. Ono, A. Hayashi, and A. Okazawa Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis Eur J Immunol 40 2010 2409 2422
-
(2010)
Eur J Immunol
, vol.40
, pp. 2409-2422
-
-
Mikami, Y.1
Kanai, T.2
Sujino, T.3
Ono, Y.4
Hayashi, A.5
Okazawa, A.6
-
101
-
-
0034013685
-
Regulatory role of mature B cells in a murine model of inflammatory bowel disease
-
E. Mizoguchi, A. Mizoguchi, F.I. Preffer, and A.K. Bhan Regulatory role of mature B cells in a murine model of inflammatory bowel disease Int Immunol 12 2000 597 605
-
(2000)
Int Immunol
, vol.12
, pp. 597-605
-
-
Mizoguchi, E.1
Mizoguchi, A.2
Preffer, F.I.3
Bhan, A.K.4
-
102
-
-
0036197923
-
Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
-
A. Mizoguchi, E. Mizoguchi, H. Takedatsu, R.S. Blumberg, and A.K. Bhan Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation Immunity 16 2002 219 230
-
(2002)
Immunity
, vol.16
, pp. 219-230
-
-
Mizoguchi, A.1
Mizoguchi, E.2
Takedatsu, H.3
Blumberg, R.S.4
Bhan, A.K.5
-
103
-
-
33847410164
-
Dependence of intestinal granuloma formation on unique myeloid DC-like cells
-
A. Mizoguchi, A. Ogawa, H. Takedatsu, K. Sugimoto, Y. Shimomura, and K. Shirane Dependence of intestinal granuloma formation on unique myeloid DC-like cells J Clin Invest 117 2007 605 615
-
(2007)
J Clin Invest
, vol.117
, pp. 605-615
-
-
Mizoguchi, A.1
Ogawa, A.2
Takedatsu, H.3
Sugimoto, K.4
Shimomura, Y.5
Shirane, K.6
-
104
-
-
84862201512
-
Cyclosporine or infliximab as rescue therapy in severe refractory ulcerative colitis: Early and long-term data from a retrospective observational study
-
F. Mocciaro, S. Renna, A. Orlando, G. Rizzuto, E. Sinagra, and E. Orlando Cyclosporine or infliximab as rescue therapy in severe refractory ulcerative colitis: Early and long-term data from a retrospective observational study J Crohns Colitis 6 2012 681 686
-
(2012)
J Crohns Colitis
, vol.6
, pp. 681-686
-
-
Mocciaro, F.1
Renna, S.2
Orlando, A.3
Rizzuto, G.4
Sinagra, E.5
Orlando, E.6
-
105
-
-
0027922467
-
Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice
-
P. Mombaerts, E. Mizoguchi, M.J. Grusby, L.H. Glimcher, A.K. Bhan, and S. Tonegawa Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice Cell 75 1993 274 282
-
(1993)
Cell
, vol.75
, pp. 274-282
-
-
Mombaerts, P.1
Mizoguchi, E.2
Grusby, M.J.3
Glimcher, L.H.4
Bhan, A.K.5
Tonegawa, S.6
-
106
-
-
0037310024
-
The many faces of macrophage activation
-
D.M. Mosser The many faces of macrophage activation J Leukoc Biol 73 2003 209 212
-
(2003)
J Leukoc Biol
, vol.73
, pp. 209-212
-
-
Mosser, D.M.1
-
107
-
-
79952506848
-
Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages
-
H. Naruse, T. Hisamatsu, Y. Yamauchi, J.E. Chang, K. Matsuoka, and M.T. Kitazume Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages Clin Exp Immunol 164 2011 137 144
-
(2011)
Clin Exp Immunol
, vol.164
, pp. 137-144
-
-
Naruse, H.1
Hisamatsu, T.2
Yamauchi, Y.3
Chang, J.E.4
Matsuoka, K.5
Kitazume, M.T.6
-
108
-
-
33846214034
-
Bone marrow retaining colitogenic CD4+T cells may be a pathogenic reservoir for chronic colitis
-
Y. Nemoto, T. Kanai, S. Makita, R. Okamoto, T. Totsuka, and K. Takeda Bone marrow retaining colitogenic CD4+T cells may be a pathogenic reservoir for chronic colitis Gastroenterology 132 2007 176 189
-
(2007)
Gastroenterology
, vol.132
, pp. 176-189
-
-
Nemoto, Y.1
Kanai, T.2
Makita, S.3
Okamoto, R.4
Totsuka, T.5
Takeda, K.6
-
109
-
-
34047173496
-
Epithelial NEMO links innate immunity to chronic intestinal inflammation
-
A. Nenci, C. Becker, A. Wullaert, R. Gareus, G. van Loo, and S. Danese Epithelial NEMO links innate immunity to chronic intestinal inflammation Nature 446 2007 557 561
-
(2007)
Nature
, vol.446
, pp. 557-561
-
-
Nenci, A.1
Becker, C.2
Wullaert, A.3
Gareus, R.4
Van Loo, G.5
Danese, S.6
-
110
-
-
34548130847
-
Reduced mucosal antimicrobial activity in Crohn's disease of the colon
-
S. Nuding, K. Fellermann, J. Wehkamp, and E.F. Stange Reduced mucosal antimicrobial activity in Crohn's disease of the colon Gut 56 2007 1240 1247
-
(2007)
Gut
, vol.56
, pp. 1240-1247
-
-
Nuding, S.1
Fellermann, K.2
Wehkamp, J.3
Stange, E.F.4
-
111
-
-
65749091607
-
A protective function for interleukin 17A in T cell-mediated intestinal inflammation
-
W. O'Connor Jr., M. Kamanaka, C.J. Booth, T. Town, S. Nakae, and Y. Iwakura A protective function for interleukin 17A in T cell-mediated intestinal inflammation Nat Immunol 10 2009 603 609
-
(2009)
Nat Immunol
, vol.10
, pp. 603-609
-
-
O'Connor, Jr.W.1
Kamanaka, M.2
Booth, C.J.3
Town, T.4
Nakae, S.5
Iwakura, Y.6
-
112
-
-
84859801314
-
Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis
-
H. Ogata, J. Kato, F. Hirai, N. Hida, T. Matsui, and T. Matsumoto Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis Inflamm Bowel Dis 18 2012 803 808
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 803-808
-
-
Ogata, H.1
Kato, J.2
Hirai, F.3
Hida, N.4
Matsui, T.5
Matsumoto, T.6
-
113
-
-
33747790601
-
A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis
-
H. Ogata, T. Matsui, M. Nakamura, M. Iida, M. Takazoe, and Y. Suzuki A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis Gut 55 2006 1255 1262
-
(2006)
Gut
, vol.55
, pp. 1255-1262
-
-
Ogata, H.1
Matsui, T.2
Nakamura, M.3
Iida, M.4
Takazoe, M.5
Suzuki, Y.6
-
114
-
-
0842324613
-
Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice
-
A. Ogawa, A. Andoh, Y. Araki, T. Bamba, and Y. Fujiyama Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice Clin Immunol 110 2004 55 62
-
(2004)
Clin Immunol
, vol.110
, pp. 55-62
-
-
Ogawa, A.1
Andoh, A.2
Araki, Y.3
Bamba, T.4
Fujiyama, Y.5
-
115
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Y. Ogura, D.K. Bonen, N. Inohara, D.L. Nicolae, F.F. Chen, and R. Ramos A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease Nature 411 2001 603 606
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
-
116
-
-
84860216630
-
Microbial exposure during early life has persistent effects on natural killer T cell function
-
T. Olszak, D. An, S. Zeissig, M.P. Vera, J. Richter, and A. Franke Microbial exposure during early life has persistent effects on natural killer T cell function Science 336 2012 489 493
-
(2012)
Science
, vol.336
, pp. 489-493
-
-
Olszak, T.1
An, D.2
Zeissig, S.3
Vera, M.P.4
Richter, J.5
Franke, A.6
-
117
-
-
84867654808
-
T-helper 17 and interleukin-17-producing lymphoid tissue inducer-like T cells make different contributions to colitis in mice
-
10.1053/j.gastro.2012.07.108 (Epub ahead of print)
-
Y. Ono, T. Kanai, T. Sujino, Y. Nemoto, Y. Kanai, and Y. Mikami T-helper 17 and interleukin-17-producing lymphoid tissue inducer-like T cells make different contributions to colitis in mice Gastroenterology 2012 10.1053/j.gastro.2012.07.108 (Epub ahead of print)
-
(2012)
Gastroenterology
-
-
Ono, Y.1
Kanai, T.2
Sujino, T.3
Nemoto, Y.4
Kanai, Y.5
Mikami, Y.6
-
118
-
-
84863105536
-
Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease
-
E. Papa, M. Docktor, C. Smillie, S. Weber, S.P. Preheim, and D. Gevers Non-invasive mapping of the gastrointestinal microbiota identifies children with inflammatory bowel disease PLoS One 7 2012 e39242
-
(2012)
PLoS One
, vol.7
, pp. 39242
-
-
Papa, E.1
Docktor, M.2
Smillie, C.3
Weber, S.4
Preheim, S.P.5
Gevers, D.6
-
119
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
M. Parkes, J.C. Barrett, N.J. Prescott, M. Tremelling, C.A. Anderson, and S.A. Fisher Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility Nat Genet 39 2007 830 832
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
Tremelling, M.4
Anderson, C.A.5
Fisher, S.A.6
-
120
-
-
36749055773
-
TNFSF15 is an ethnic-specific IBD gene
-
Y. Picornell, L. Mei, K. Taylor, H. Yang, S.R. Targan, and J.I. Rotter TNFSF15 is an ethnic-specific IBD gene Inflamm Bowel Dis 13 2007 1333 1338
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 1333-1338
-
-
Picornell, Y.1
Mei, L.2
Taylor, K.3
Yang, H.4
Targan, S.R.5
Rotter, J.I.6
-
121
-
-
80051550866
-
Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2
-
T.S. Plantinga, T.O. Crisan, M. Oosting, F.L. van de Veerdonk, D.J. de Jong, and D.J. Philpott Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2 Gut 60 2011 1229 1235
-
(2011)
Gut
, vol.60
, pp. 1229-1235
-
-
Plantinga, T.S.1
Crisan, T.O.2
Oosting, M.3
Van De Veerdonk, F.L.4
De Jong, D.J.5
Philpott, D.J.6
-
122
-
-
34247566585
-
A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5
-
N.J. Prescott, S.A. Fisher, A. Franke, J. Hampe, C.M. Onnie, and D. Soars A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5 Gastroenterology 132 2007 1665 1671
-
(2007)
Gastroenterology
, vol.132
, pp. 1665-1671
-
-
Prescott, N.J.1
Fisher, S.A.2
Franke, A.3
Hampe, J.4
Onnie, C.M.5
Soars, D.6
-
123
-
-
0033529049
-
Infliximab for the treatment of fistulas in patients with Crohn's disease
-
D.H. Present, P. Rutgeerts, S. Targan, S.B. Hanauer, L. Mayer, and R.A. van Hogezand Infliximab for the treatment of fistulas in patients with Crohn's disease N Engl J Med 340 1999 1398 1405
-
(1999)
N Engl J Med
, vol.340
, pp. 1398-1405
-
-
Present, D.H.1
Rutgeerts, P.2
Targan, S.3
Hanauer, S.B.4
Mayer, L.5
Van Hogezand, R.A.6
-
124
-
-
79955859430
-
Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: Results of a randomised controlled trial
-
W. Reinisch, W.J. Sandborn, D.W. Hommes, G. D'Haens, S. Hanauer, and S. Schreiber Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: Results of a randomised controlled trial Gut 60 2011 780 787
-
(2011)
Gut
, vol.60
, pp. 780-787
-
-
Reinisch, W.1
Sandborn, W.J.2
Hommes, D.W.3
D'Haens, G.4
Hanauer, S.5
Schreiber, S.6
-
125
-
-
18244387204
-
Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells
-
M. Rimoldi, M. Chieppa, V. Salucci, F. Avogadri, A. Sonzogni, and G.M. Sampietro Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells Nat Immunol 6 2005 507 514
-
(2005)
Nat Immunol
, vol.6
, pp. 507-514
-
-
Rimoldi, M.1
Chieppa, M.2
Salucci, V.3
Avogadri, F.4
Sonzogni, A.5
Sampietro, G.M.6
-
126
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
J.D. Rioux, R.J. Xavier, K.D. Taylor, M.S. Silverberg, P. Goyette, and A. Huett Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis Nat Genet 39 2007 596 604
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
-
127
-
-
0031802150
-
Isolation and phenotypic characterization of colonic macrophages
-
G. Rogler, M. Hausmann, D. Vogl, E. Aschenbrenner, T. Andus, and W. Falk Isolation and phenotypic characterization of colonic macrophages Clin Exp Immunol 112 1998 205 215
-
(1998)
Clin Exp Immunol
, vol.112
, pp. 205-215
-
-
Rogler, G.1
Hausmann, M.2
Vogl, D.3
Aschenbrenner, E.4
Andus, T.5
Falk, W.6
-
128
-
-
79956311926
-
The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
-
J.L. Round, S.M. Lee, J. Li, G. Tran, B. Jabri, and T.A. Chatila The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota Science 332 2011 974 977
-
(2011)
Science
, vol.332
, pp. 974-977
-
-
Round, J.L.1
Lee, S.M.2
Li, J.3
Tran, G.4
Jabri, B.5
Chatila, T.A.6
-
129
-
-
77954738601
-
Inducible Foxp3+regulatory T-cell development by a commensal bacterium of the intestinal microbiota
-
J.L. Round, and S.K. Mazmanian Inducible Foxp3+regulatory T-cell development by a commensal bacterium of the intestinal microbiota Proc Natl Acad Sci U S A 107 2010 12204 12209
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 12204-12209
-
-
Round, J.L.1
Mazmanian, S.K.2
-
130
-
-
0032833517
-
Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease
-
P. Rutgeerts, G. D'Haens, S. Targan, E. Vasiliauskas, S.B. Hanauer, and D.H. Present Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease Gastroenterology 117 1999 761 769
-
(1999)
Gastroenterology
, vol.117
, pp. 761-769
-
-
Rutgeerts, P.1
D'Haens, G.2
Targan, S.3
Vasiliauskas, E.4
Hanauer, S.B.5
Present, D.H.6
-
131
-
-
28844473957
-
Infliximab for induction and maintenance therapy for ulcerative colitis
-
P. Rutgeerts, W.J. Sandborn, B.G. Feagan, W. Reinisch, A. Olson, and J. Johanns Infliximab for induction and maintenance therapy for ulcerative colitis N Engl J Med 353 2005 2462 2476
-
(2005)
N Engl J Med
, vol.353
, pp. 2462-2476
-
-
Rutgeerts, P.1
Sandborn, W.J.2
Feagan, B.G.3
Reinisch, W.4
Olson, A.5
Johanns, J.6
-
132
-
-
70350093623
-
Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease
-
A. Sakuraba, T. Sato, N. Kamada, M. Kitazume, A. Sugita, and T. Hibi Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease Gastroenterology 137 2009 1736 1745
-
(2009)
Gastroenterology
, vol.137
, pp. 1736-1745
-
-
Sakuraba, A.1
Sato, T.2
Kamada, N.3
Kitazume, M.4
Sugita, A.5
Hibi, T.6
-
133
-
-
74049122536
-
Enteric defensins are essential regulators of intestinal microbial ecology
-
N.H. Salzman, K. Hung, D. Haribhai, H. Chu, J. Karlsson-Sjoberg, and E. Amir Enteric defensins are essential regulators of intestinal microbial ecology Nat Immunol 11 2010 76 83
-
(2010)
Nat Immunol
, vol.11
, pp. 76-83
-
-
Salzman, N.H.1
Hung, K.2
Haribhai, D.3
Chu, H.4
Karlsson-Sjoberg, J.5
Amir, E.6
-
134
-
-
27644441529
-
Natalizumab induction and maintenance therapy for Crohn's disease
-
W.J. Sandborn, J.F. Colombel, R. Enns, B.G. Feagan, S.B. Hanauer, and I.C. Lawrance Natalizumab induction and maintenance therapy for Crohn's disease N Engl J Med 353 2005 1912 1925
-
(2005)
N Engl J Med
, vol.353
, pp. 1912-1925
-
-
Sandborn, W.J.1
Colombel, J.F.2
Enns, R.3
Feagan, B.G.4
Hanauer, S.B.5
Lawrance, I.C.6
-
135
-
-
53049091561
-
A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
-
W.J. Sandborn, B.G. Feagan, R.N. Fedorak, E. Scherl, M.R. Fleisher, and S. Katz A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease Gastroenterology 135 2008 1130 1141
-
(2008)
Gastroenterology
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.J.1
Feagan, B.G.2
Fedorak, R.N.3
Scherl, E.4
Fleisher, M.R.5
Katz, S.6
-
136
-
-
34447523749
-
Certolizumab pegol for the treatment of Crohn's disease
-
W.J. Sandborn, B.G. Feagan, S. Stoinov, P.J. Honiball, P. Rutgeerts, and D. Mason Certolizumab pegol for the treatment of Crohn's disease N Engl J Med 357 2007 228 238
-
(2007)
N Engl J Med
, vol.357
, pp. 228-238
-
-
Sandborn, W.J.1
Feagan, B.G.2
Stoinov, S.3
Honiball, P.J.4
Rutgeerts, P.5
Mason, D.6
-
137
-
-
84856163835
-
Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis
-
W.J. Sandborn, G. van Assche, W. Reinisch, J.F. Colombel, G. D'Haens, and D.C. Wolf Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis Gastroenterology 142 257-265 2012 e251 e253
-
(2012)
Gastroenterology
, vol.142
, Issue.257-265
-
-
Sandborn, W.J.1
Van Assche, G.2
Reinisch, W.3
Colombel, J.F.4
D'Haens, G.5
Wolf, D.C.6
-
138
-
-
57449118239
-
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense
-
N. Satoh-Takayama, C.A. Vosshenrich, S. Lesjean-Pottier, S. Sawa, M. Lochner, and F. Rattis Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense Immunity 29 2008 958 970
-
(2008)
Immunity
, vol.29
, pp. 958-970
-
-
Satoh-Takayama, N.1
Vosshenrich, C.A.2
Lesjean-Pottier, S.3
Sawa, S.4
Lochner, M.5
Rattis, F.6
-
139
-
-
78049385155
-
Lineage relationship analysis of RORgammat+innate lymphoid cells
-
S. Sawa, M. Cherrier, M. Lochner, N. Satoh-Takayama, H.J. Fehling, and F. Langa Lineage relationship analysis of RORgammat+innate lymphoid cells Science 330 2010 665 669
-
(2010)
Science
, vol.330
, pp. 665-669
-
-
Sawa, S.1
Cherrier, M.2
Lochner, M.3
Satoh-Takayama, N.4
Fehling, H.J.5
Langa, F.6
-
140
-
-
34948821265
-
TREM-1-expressing intestinal macrophages crucially amplify chronic inflammation in experimental colitis and inflammatory bowel diseases
-
M. Schenk, A. Bouchon, F. Seibold, and C. Mueller TREM-1-expressing intestinal macrophages crucially amplify chronic inflammation in experimental colitis and inflammatory bowel diseases J Clin Invest 117 2007 3097 3106
-
(2007)
J Clin Invest
, vol.117
, pp. 3097-3106
-
-
Schenk, M.1
Bouchon, A.2
Seibold, F.3
Mueller, C.4
-
141
-
-
34249337149
-
Adaptations of intestinal macrophages to an antigen-rich environment
-
M. Schenk, and C. Mueller Adaptations of intestinal macrophages to an antigen-rich environment Semin Immunol 19 2007 84 93
-
(2007)
Semin Immunol
, vol.19
, pp. 84-93
-
-
Schenk, M.1
Mueller, C.2
-
142
-
-
24144483087
-
A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease
-
S. Schreiber, P. Rutgeerts, R.N. Fedorak, M. Khaliq-Kareemi, M.A. Kamm, and M. Boivin A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease Gastroenterology 129 2005 807 818
-
(2005)
Gastroenterology
, vol.129
, pp. 807-818
-
-
Schreiber, S.1
Rutgeerts, P.2
Fedorak, R.N.3
Khaliq-Kareemi, M.4
Kamm, M.A.5
Boivin, M.6
-
143
-
-
0032412057
-
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
-
R.K. Sellon, S. Tonkonogy, M. Schultz, L.A. Dieleman, W. Grenther, and E. Balish Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice Infect Immun 66 1998 5224 5231
-
(1998)
Infect Immun
, vol.66
, pp. 5224-5231
-
-
Sellon, R.K.1
Tonkonogy, S.2
Schultz, M.3
Dieleman, L.A.4
Grenther, W.5
Balish, E.6
-
144
-
-
34548810954
-
A novel role for defensins in intestinal homeostasis: Regulation of IL-1beta secretion
-
J. Shi, S. Aono, W. Lu, A.J. Ouellette, X. Hu, and Y. Ji A novel role for defensins in intestinal homeostasis: Regulation of IL-1beta secretion J Immunol 179 2007 1245 1253
-
(2007)
J Immunol
, vol.179
, pp. 1245-1253
-
-
Shi, J.1
Aono, S.2
Lu, W.3
Ouellette, A.J.4
Hu, X.5
Ji, Y.6
-
146
-
-
79951828164
-
Upregulated IL-7 receptor alpha expression on colitogenic memory CD4+T cells may participate in the development and persistence of chronic colitis
-
T. Shinohara, Y. Nemoto, T. Kanai, K. Kameyama, R. Okamoto, and K. Tsuchiya Upregulated IL-7 receptor alpha expression on colitogenic memory CD4+T cells may participate in the development and persistence of chronic colitis J Immunol 186 2011 2623 2632
-
(2011)
J Immunol
, vol.186
, pp. 2623-2632
-
-
Shinohara, T.1
Nemoto, Y.2
Kanai, T.3
Kameyama, K.4
Okamoto, R.5
Tsuchiya, K.6
-
147
-
-
84855698480
-
Infliximab or cyclosporine as rescue therapy in hospitalized patients with steroid-refractory ulcerative colitis: A retrospective observational study
-
M. Sjoberg, A. Walch, M. Meshkat, A. Gustavsson, G. Jarnerot, and H. Vogelsang Infliximab or cyclosporine as rescue therapy in hospitalized patients with steroid-refractory ulcerative colitis: A retrospective observational study Inflamm Bowel Dis 18 2012 212 218
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 212-218
-
-
Sjoberg, M.1
Walch, A.2
Meshkat, M.3
Gustavsson, A.4
Jarnerot, G.5
Vogelsang, H.6
-
148
-
-
0035451799
-
Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activities
-
P.D. Smith, L.E. Smythies, M. Mosteller-Barnum, D.A. Sibley, M.W. Russell, and M. Merger Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activities J Immunol 167 2001 2651 2656
-
(2001)
J Immunol
, vol.167
, pp. 2651-2656
-
-
Smith, P.D.1
Smythies, L.E.2
Mosteller-Barnum, M.3
Sibley, D.A.4
Russell, M.W.5
Merger, M.6
-
149
-
-
13744256812
-
Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity
-
L.E. Smythies, M. Sellers, R.H. Clements, M. Mosteller-Barnum, G. Meng, and W.H. Benjamin Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity J Clin Invest 115 2005 66 75
-
(2005)
J Clin Invest
, vol.115
, pp. 66-75
-
-
Smythies, L.E.1
Sellers, M.2
Clements, R.H.3
Mosteller-Barnum, M.4
Meng, G.5
Benjamin, W.H.6
-
150
-
-
33645019411
-
Specificities of the fecal microbiota in inflammatory bowel disease
-
H. Sokol, P. Seksik, L. Rigottier-Gois, C. Lay, P. Lepage, and I. Podglajen Specificities of the fecal microbiota in inflammatory bowel disease Inflamm Bowel Dis 12 2006 106 111
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 106-111
-
-
Sokol, H.1
Seksik, P.2
Rigottier-Gois, L.3
Lay, C.4
Lepage, P.5
Podglajen, I.6
-
151
-
-
84861989207
-
Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria
-
G.F. Sonnenberg, L.A. Monticelli, T. Alenghat, T.C. Fung, N.A. Hutnick, and J. Kunisawa Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria Science 336 2012 1321 1325
-
(2012)
Science
, vol.336
, pp. 1321-1325
-
-
Sonnenberg, G.F.1
Monticelli, L.A.2
Alenghat, T.3
Fung, T.C.4
Hutnick, N.A.5
Kunisawa, J.6
-
152
-
-
78751706261
-
CD4 (+) lymphoid tissue-inducer cells promote innate immunity in the gut
-
G.F. Sonnenberg, L.A. Monticelli, M.M. Elloso, L.A. Fouser, and D. Artis CD4 (+) lymphoid tissue-inducer cells promote innate immunity in the gut Immunity 34 2011 122 134
-
(2011)
Immunity
, vol.34
, pp. 122-134
-
-
Sonnenberg, G.F.1
Monticelli, L.A.2
Elloso, M.M.3
Fouser, L.A.4
Artis, D.5
-
153
-
-
78650310810
-
The expanding family of innate lymphoid cells: Regulators and effectors of immunity and tissue remodeling
-
H. Spits, and J.P. Di Santo The expanding family of innate lymphoid cells: Regulators and effectors of immunity and tissue remodeling Nat Immunol 12 2011 21 27
-
(2011)
Nat Immunol
, vol.12
, pp. 21-27
-
-
Spits, H.1
Di Santo, J.P.2
-
154
-
-
80052130713
-
Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation
-
N. Steck, M. Hoffmann, I.G. Sava, S.C. Kim, H. Hahne, and S.L. Tonkonogy Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation Gastroenterology 141 2011 959 971
-
(2011)
Gastroenterology
, vol.141
, pp. 959-971
-
-
Steck, N.1
Hoffmann, M.2
Sava, I.G.3
Kim, S.C.4
Hahne, H.5
Tonkonogy, S.L.6
-
155
-
-
46949086111
-
A rush to judgment on Th17
-
L. Steinman A rush to judgment on Th17 J Exp Med 205 2008 1517 1522
-
(2008)
J Exp Med
, vol.205
, pp. 1517-1522
-
-
Steinman, L.1
-
156
-
-
34247555353
-
Differentiation and function of Th17 T cells
-
B. Stockinger, and M. Veldhoen Differentiation and function of Th17 T cells Curr Opin Immunol 19 2007 281 286
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 281-286
-
-
Stockinger, B.1
Veldhoen, M.2
-
157
-
-
38849141814
-
IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis
-
K. Sugimoto, A. Ogawa, E. Mizoguchi, Y. Shimomura, A. Andoh, and A.K. Bhan IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis J Clin Invest 118 2008 534 544
-
(2008)
J Clin Invest
, vol.118
, pp. 534-544
-
-
Sugimoto, K.1
Ogawa, A.2
Mizoguchi, E.3
Shimomura, Y.4
Andoh, A.5
Bhan, A.K.6
-
158
-
-
80052122798
-
Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells
-
T. Sujino, T. Kanai, Y. Ono, Y. Mikami, A. Hayashi, and T. Doi Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells Gastroenterology 141 2011 1014 1023
-
(2011)
Gastroenterology
, vol.141
, pp. 1014-1023
-
-
Sujino, T.1
Kanai, T.2
Ono, Y.3
Mikami, Y.4
Hayashi, A.5
Doi, T.6
-
159
-
-
0036140777
-
Mucosal flora in inflammatory bowel disease
-
A. Swidsinski, A. Ladhoff, A. Pernthaler, S. Swidsinski, V. Loening-Baucke, and M. Ortner Mucosal flora in inflammatory bowel disease Gastroenterology 122 2002 44 54
-
(2002)
Gastroenterology
, vol.122
, pp. 44-54
-
-
Swidsinski, A.1
Ladhoff, A.2
Pernthaler, A.3
Swidsinski, S.4
Loening-Baucke, V.5
Ortner, M.6
-
160
-
-
77951902290
-
Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset
-
Y. Takada, T. Hisamatsu, N. Kamada, M.T. Kitazume, H. Honda, and Y. Oshima Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset J Immunol 184 2010 2671 2676
-
(2010)
J Immunol
, vol.184
, pp. 2671-2676
-
-
Takada, Y.1
Hisamatsu, T.2
Kamada, N.3
Kitazume, M.T.4
Honda, H.5
Oshima, Y.6
-
161
-
-
44349164525
-
Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease
-
H. Takaishi, T. Matsuki, A. Nakazawa, T. Takada, S. Kado, and T. Asahara Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease Int J Med Microbiol 298 2008 463 472
-
(2008)
Int J Med Microbiol
, vol.298
, pp. 463-472
-
-
Takaishi, H.1
Matsuki, T.2
Nakazawa, A.3
Takada, T.4
Kado, S.5
Asahara, T.6
-
162
-
-
60549102720
-
Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22
-
H. Takatori, Y. Kanno, W.T. Watford, C.M. Tato, G. Weiss, and I.I. Ivanov Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22 J Exp Med 206 2009 35 41
-
(2009)
J Exp Med
, vol.206
, pp. 35-41
-
-
Takatori, H.1
Kanno, Y.2
Watford, W.T.3
Tato, C.M.4
Weiss, G.5
Ivanov, I.I.6
-
163
-
-
77956190936
-
Imbalance of NKp44 (+) NKp46(-) and NKp44(-)NKp46 (+) natural killer cells in the intestinal mucosa of patients with Crohn's disease
-
(892 e881-883)
-
T. Takayama, N. Kamada, H. Chinen, S. Okamoto, M.T. Kitazume, and J. Chang Imbalance of NKp44 (+) NKp46(-) and NKp44(-)NKp46 (+) natural killer cells
-
(2010)
Gastroenterology
, vol.139
, pp. 882-892
-
-
Takayama, T.1
Kamada, N.2
Chinen, H.3
Okamoto, S.4
Kitazume, M.T.5
Chang, J.6
-
164
-
-
34248225010
-
Denatured human alpha-defensin attenuates the bactericidal activity and the stability against enzymatic digestion
-
H. Tanabe, T. Ayabe, A. Maemoto, C. Ishikawa, Y. Inaba, and R. Sato Denatured human alpha-defensin attenuates the bactericidal activity and the stability against enzymatic digestion Biochem Biophys Res Commun 358 2007 349 355
-
(2007)
Biochem Biophys Res Commun
, vol.358
, pp. 349-355
-
-
Tanabe, H.1
Ayabe, T.2
Maemoto, A.3
Ishikawa, C.4
Inaba, Y.5
Sato, R.6
-
165
-
-
34247884424
-
Natalizumab for the treatment of active Crohn's disease: Results of the ENCORE Trial
-
S.R. Targan, B.G. Feagan, R.N. Fedorak, B.A. Lashner, R. Panaccione, and D.H. Present Natalizumab for the treatment of active Crohn's disease: Results of the ENCORE Trial Gastroenterology 132 2007 1672 1683
-
(2007)
Gastroenterology
, vol.132
, pp. 1672-1683
-
-
Targan, S.R.1
Feagan, B.G.2
Fedorak, R.N.3
Lashner, B.A.4
Panaccione, R.5
Present, D.H.6
-
166
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease.Crohn's Disease cA2 Study Group
-
S.R. Targan, S.B. Hanauer, S.J. van Deventer, L. Mayer, D.H. Present, and T. Braakman A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease.Crohn's Disease cA2 Study Group N Engl J Med 337 1997 1029 1035
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.3
Mayer, L.4
Present, D.H.5
Braakman, T.6
-
167
-
-
84860136921
-
Abnormal activation of autophagy-induced crinophagy in Paneth cells from patients with Crohn's disease
-
E. Thachil, J.P. Hugot, B. Arbeille, R. Paris, A. Grodet, and M. Peuchmaur Abnormal activation of autophagy-induced crinophagy in Paneth cells from patients with Crohn's disease Gastroenterology 142 1097-1099 2012 e1094
-
(2012)
Gastroenterology
, vol.142
, Issue.1097-1099
, pp. 1094
-
-
Thachil, E.1
Hugot, J.P.2
Arbeille, B.3
Paris, R.4
Grodet, A.5
Peuchmaur, M.6
-
168
-
-
59749094752
-
TNFSF15 polymorphisms are associated with susceptibility to inflammatory bowel disease in a new European cohort
-
R. Thiebaut, S. Kotti, C. Jung, F. Merlin, J.F. Colombel, and M. Lemann TNFSF15 polymorphisms are associated with susceptibility to inflammatory bowel disease in a new European cohort Am J Gastroenterol 104 2009 384 391
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 384-391
-
-
Thiebaut, R.1
Kotti, S.2
Jung, C.3
Merlin, F.4
Colombel, J.F.5
Lemann, M.6
-
169
-
-
58149397203
-
Colitogenic CD4+effector-memory T cells actively recirculate in chronic colitic mice
-
T. Tomita, T. Kanai, Y. Nemoto, T. Fujii, K. Nozaki, and R. Okamoto Colitogenic CD4+effector-memory T cells actively recirculate in chronic colitic mice Inflamm Bowel Dis 14 2008 1630 1640
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 1630-1640
-
-
Tomita, T.1
Kanai, T.2
Nemoto, Y.3
Fujii, T.4
Nozaki, K.5
Okamoto, R.6
-
170
-
-
40449131153
-
Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis
-
T. Tomita, T. Kanai, Y. Nemoto, T. Totsuka, R. Okamoto, and K. Tsuchiya Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis J Immunol 180 2008 383 390
-
(2008)
J Immunol
, vol.180
, pp. 383-390
-
-
Tomita, T.1
Kanai, T.2
Nemoto, Y.3
Totsuka, T.4
Okamoto, R.5
Tsuchiya, K.6
-
171
-
-
34247157433
-
IL-7 is essential for the development and the persistence of chronic colitis
-
T. Totsuka, T. Kanai, Y. Nemoto, S. Makita, R. Okamoto, and K. Tsuchiya IL-7 is essential for the development and the persistence of chronic colitis J Immunol 178 2007 4737 4748
-
(2007)
J Immunol
, vol.178
, pp. 4737-4748
-
-
Totsuka, T.1
Kanai, T.2
Nemoto, Y.3
Makita, S.4
Okamoto, R.5
Tsuchiya, K.6
-
172
-
-
46049089270
-
Contribution of TNFSF15 gene variants to Crohn's disease susceptibility confirmed in UK population
-
M. Tremelling, C. Berzuini, D. Massey, F. Bredin, C. Price, and C. Dawson Contribution of TNFSF15 gene variants to Crohn's disease susceptibility confirmed in UK population Inflamm Bowel Dis 14 2008 733 737
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 733-737
-
-
Tremelling, M.1
Berzuini, C.2
Massey, D.3
Bredin, F.4
Price, C.5
Dawson, C.6
-
173
-
-
84887427250
-
Mucosal CXCR4+IgG plasma cells contribute to the pathogenesis of human ulcerative colitis through FcγR-mediated CD14 macrophage activation
-
M. Uo, T. Hisamatsu, J. Miyoshi, D. Kaito, K. Yoneno, and M.T. Kitazume Mucosal CXCR4+IgG plasma cells contribute to the pathogenesis of human ulcerative colitis through FcγR-mediated CD14 macrophage activation Gut 2012, Sep 26
-
(2012)
Gut
-
-
Uo, M.1
Hisamatsu, T.2
Miyoshi, J.3
Kaito, D.4
Yoneno, K.5
Kitazume, M.T.6
-
174
-
-
80054122238
-
The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine
-
S. Vaishnava, M. Yamamoto, K.M. Severson, K.A. Ruhn, X. Yu, and O. Koren The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine Science 334 2011 255 258
-
(2011)
Science
, vol.334
, pp. 255-258
-
-
Vaishnava, S.1
Yamamoto, M.2
Severson, K.M.3
Ruhn, K.A.4
Yu, X.5
Koren, O.6
-
175
-
-
22844445587
-
Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease
-
G. Van Assche, M. Van Ranst, R. Sciot, B. Dubois, S. Vermeire, and M. Noman Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease N Engl J Med 353 2005 362 368
-
(2005)
N Engl J Med
, vol.353
, pp. 362-368
-
-
Van Assche, G.1
Van Ranst, M.2
Sciot, R.3
Dubois, B.4
Vermeire, S.5
Noman, M.6
-
176
-
-
0029050742
-
Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2)
-
H.M. van Dullemen, S.J. van Deventer, D.W. Hommes, H.A. Bijl, J. Jansen, and G.N. Tytgat Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2) Gastroenterology 109 1995 129 135
-
(1995)
Gastroenterology
, vol.109
, pp. 129-135
-
-
Van Dullemen, H.M.1
Van Deventer, S.J.2
Hommes, D.W.3
Bijl, H.A.4
Jansen, J.5
Tytgat, G.N.6
-
177
-
-
32244442562
-
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
M. Veldhoen, R.J. Hocking, C.J. Atkins, R.M. Locksley, and B. Stockinger TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells Immunity 24 2006 179 189
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
178
-
-
34249723247
-
Allergies, infections and the hygiene hypothesis-the epidemiological evidence
-
E. von Mutius Allergies, infections and the hygiene hypothesis-the epidemiological evidence Immunobiology 212 2007 433 439
-
(2007)
Immunobiology
, vol.212
, pp. 433-439
-
-
Von Mutius, E.1
-
179
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
P. Walter, and D. Ron The unfolded protein response: From stress pathway to homeostatic regulation Science 334 2011 1081 1086
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
180
-
-
0037326647
-
Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice
-
N. Watanabe, K. Ikuta, K. Okazaki, H. Nakase, Y. Tabata, and M. Matsuura Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice Dig Dis Sci 48 2003 408 414
-
(2003)
Dig Dis Sci
, vol.48
, pp. 408-414
-
-
Watanabe, N.1
Ikuta, K.2
Okazaki, K.3
Nakase, H.4
Tabata, Y.5
Matsuura, M.6
-
181
-
-
33744984785
-
Th17: An effector CD4 T cell lineage with regulatory T cell ties
-
C.T. Weaver, L.E. Harrington, P.R. Mangan, M. Gavrieli, and K.M. Murphy Th17: An effector CD4 T cell lineage with regulatory T cell ties Immunity 24 2006 677 688
-
(2006)
Immunity
, vol.24
, pp. 677-688
-
-
Weaver, C.T.1
Harrington, L.E.2
Mangan, P.R.3
Gavrieli, M.4
Murphy, K.M.5
-
182
-
-
29144483937
-
Reduced Paneth cell alpha-defensins in ileal Crohn's disease
-
J. Wehkamp, N.H. Salzman, E. Porter, S. Nuding, M. Weichenthal, and R.E. Petras Reduced Paneth cell alpha-defensins in ileal Crohn's disease Proc Natl Acad Sci U S A 102 2005 18129 18134
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18129-18134
-
-
Wehkamp, J.1
Salzman, N.H.2
Porter, E.3
Nuding, S.4
Weichenthal, M.5
Petras, R.E.6
-
183
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Nature 447 2007 661 678
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
184
-
-
84055191068
-
T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice
-
F. Wiede, B.J. Shields, S.H. Chew, K. Kyparissoudis, C. van Vliet, and S. Galic T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice J Clin Invest 121 2011 4758 4774
-
(2011)
J Clin Invest
, vol.121
, pp. 4758-4774
-
-
Wiede, F.1
Shields, B.J.2
Chew, S.H.3
Kyparissoudis, K.4
Van Vliet, C.5
Galic, S.6
-
185
-
-
0035877257
-
Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death
-
M.T. Wiekowski, M.W. Leach, E.W. Evans, L. Sullivan, S.C. Chen, and G. Vassileva Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death J Immunol 166 2001 7563 7570
-
(2001)
J Immunol
, vol.166
, pp. 7563-7570
-
-
Wiekowski, M.T.1
Leach, M.W.2
Evans, E.W.3
Sullivan, L.4
Chen, S.C.5
Vassileva, G.6
-
186
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
R.J. Xavier, and D.K. Podolsky Unravelling the pathogenesis of inflammatory bowel disease Nature 448 2007 427 434
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
187
-
-
27944464550
-
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
-
K. Yamazaki, D. McGovern, J. Ragoussis, M. Paolucci, H. Butler, and D. Jewell Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease Hum Mol Genet 14 2005 3499 3506
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3499-3506
-
-
Yamazaki, K.1
McGovern, D.2
Ragoussis, J.3
Paolucci, M.4
Butler, H.5
Jewell, D.6
-
188
-
-
34347357508
-
Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients
-
K. Yamazaki, Y. Onouchi, M. Takazoe, M. Kubo, Y. Nakamura, and A. Hata Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients J Hum Genet 52 2007 575 583
-
(2007)
J Hum Genet
, vol.52
, pp. 575-583
-
-
Yamazaki, K.1
Onouchi, Y.2
Takazoe, M.3
Kubo, M.4
Nakamura, Y.5
Hata, A.6
-
189
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
D. Yen, J. Cheung, H. Scheerens, F. Poulet, T. McClanahan, and B. McKenzie IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6 J Clin Invest 116 2006 1310 1316
-
(2006)
J Clin Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
-
190
-
-
33947573767
-
Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis
-
C. Zaph, A.E. Troy, B.C. Taylor, L.D. Berman-Booty, K.J. Guild, and Y. Du Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis Nature 446 2007 552 556
-
(2007)
Nature
, vol.446
, pp. 552-556
-
-
Zaph, C.1
Troy, A.E.2
Taylor, B.C.3
Berman-Booty, L.D.4
Guild, K.J.5
Du, Y.6
-
191
-
-
33845995125
-
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
-
S. Zeissig, N. Burgel, D. Gunzel, J. Richter, J. Mankertz, and U. Wahnschaffe Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease Gut 56 2007 61 72
-
(2007)
Gut
, vol.56
, pp. 61-72
-
-
Zeissig, S.1
Burgel, N.2
Gunzel, D.3
Richter, J.4
Mankertz, J.5
Wahnschaffe, U.6
-
192
-
-
33646804892
-
Critical role of IL-17 receptor signaling in acute TNBS-induced colitis
-
Z. Zhang, M. Zheng, J. Bindas, P. Schwarzenberger, and J.K. Kolls Critical role of IL-17 receptor signaling in acute TNBS-induced colitis Inflamm Bowel Dis 12 2006 382 388
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 382-388
-
-
Zhang, Z.1
Zheng, M.2
Bindas, J.3
Schwarzenberger, P.4
Kolls, J.K.5
-
193
-
-
42749096082
-
Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP
-
A. Zhernakova, E.M. Festen, L. Franke, G. Trynka, C.C. van Diemen, and A.J. Monsuur Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP Am J Hum Genet 82 2008 1202 1210
-
(2008)
Am J Hum Genet
, vol.82
, pp. 1202-1210
-
-
Zhernakova, A.1
Festen, E.M.2
Franke, L.3
Trynka, G.4
Van Diemen, C.C.5
Monsuur, A.J.6
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