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Volumn 50, Issue 4, 2011, Pages 367-373

Melatonin promotes puromycin-induced apoptosis with activation of caspase-3 and 5′-adenosine monophosphate-activated kinase-alpha in human leukemia HL-60 cells

Author keywords

5 adenosine monophosphate activated kinase alpha; apoptosis; checkpoint kinase; HL 60 cells; melatonin; puromycin

Indexed keywords

5' ADENOSINE MONOPHOSPHATE ACTIVATED KINASE ALPHA; ADENOSINE PHOSPHATE; CASPASE 3; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; MELATONIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL XL; PUROMYCIN; UNCLASSIFIED DRUG;

EID: 79954422774     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2010.00852.x     Document Type: Article
Times cited : (42)

References (56)
  • 1
    • 34247151073 scopus 로고    scopus 로고
    • Melatonin: Therapeutic and clinical utilization
    • DOI 10.1111/j.1742-1241.2006.01191.x
    • Altun A, Ugur-Altun B,. Melatonin: therapeutic and clinical utilization. Int J Clin Pract 2007; 61: 835-845. (Pubitemid 46587862)
    • (2007) International Journal of Clinical Practice , vol.61 , Issue.5 , pp. 835-845
    • Altun, A.1    Ugur-Altun, B.2
  • 3
    • 0002979059 scopus 로고
    • Melatonin: A potent, endogenous hydroxyl radical scavenger
    • Tan DX, Chen LD, Poeggeler B, et al., Melatonin: a potent, endogenous hydroxyl radical scavenger. Endocr J 1993; 1: 57-60.
    • (1993) Endocr J , vol.1 , pp. 57-60
    • Tan, D.X.1    Chen, L.D.2    Poeggeler, B.3
  • 4
    • 27644466592 scopus 로고    scopus 로고
    • A review of the multiple actions of melatonin on the immune system
    • DOI 10.1385/ENDO:27:2:189
    • Carrillo-Vico A, Guerrero JM, Lardone PJ, et al., A review of the multiple actions of melatonin on the immune system. Endocrine 2005; 27: 189-200. (Pubitemid 41558451)
    • (2005) Endocrine , vol.27 , Issue.2 , pp. 189-200
    • Carrillo-Vico, A.1    Guerrero, J.M.2    Lardone, P.J.3    Reiter, R.J.4
  • 5
    • 68249129060 scopus 로고    scopus 로고
    • Kynuramines, metabolites of melatonin and other indoles: The resurrection of an almost forgotten class of biogenic amines
    • Hardeland R, Tan DX, Reiter RJ,. Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J Pineal Res 2009; 47: 109-126.
    • (2009) J Pineal Res , vol.47 , pp. 109-126
    • Hardeland, R.1    Tan, D.X.2    Reiter, R.J.3
  • 6
    • 27744573253 scopus 로고    scopus 로고
    • Melatonin in the treatment of cancer: A systematic review of randomized controlled trials and meta-analysis
    • Mills E, Wu P, Seely D, et al., Melatonin in the treatment of cancer: a systematic review of randomized controlled trials and meta-analysis. J Pineal Res 2005; 39: 360-366.
    • (2005) J Pineal Res , vol.39 , pp. 360-366
    • Mills, E.1    Wu, P.2    Seely, D.3
  • 7
    • 79851512610 scopus 로고    scopus 로고
    • Significance and application of melatonin in the regulation of brown adipose tissue metabolism: Relation to human obesity
    • [Epub ahead of print].
    • Tan DX, Manchester LC, Fuentes-Broto L, et al., Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity. Obes Rev 2010; [Epub ahead of print].
    • (2010) Obes Rev
    • Tan, D.X.1    Manchester, L.C.2    Fuentes-Broto, L.3
  • 8
    • 77956301403 scopus 로고    scopus 로고
    • Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1)
    • Leja-Szpak A, Jaworek J, Pierzchalski P, et al., Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1). J Pineal Res 2010; 49: 248-255.
    • (2010) J Pineal Res , vol.49 , pp. 248-255
    • Leja-Szpak, A.1    Jaworek, J.2    Pierzchalski, P.3
  • 9
    • 77950838898 scopus 로고    scopus 로고
    • Melatonin and doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines
    • Fan LL, Sun GP, Wei W, et al., Melatonin and doxorubicin synergistically induce cell apoptosis in human hepatoma cell lines. World J Gastroenterol 2010; 16: 1473-1481.
    • (2010) World J Gastroenterol , vol.16 , pp. 1473-1481
    • Fan, L.L.1    Sun, G.P.2    Wei, W.3
  • 10
    • 71549153554 scopus 로고    scopus 로고
    • Synergistic antitumor effect of melatonin with several chemotherapeutic drugs on human Ewing sarcoma cancer cells: Potentiation of the extrinsic apoptotic pathway
    • Casado-Zapico S, Rodriguez-Blanco J, Garcia-Santos G, et al., Synergistic antitumor effect of melatonin with several chemotherapeutic drugs on human Ewing sarcoma cancer cells: potentiation of the extrinsic apoptotic pathway. J Pineal Res 2010; 48: 72-80.
    • (2010) J Pineal Res , vol.48 , pp. 72-80
    • Casado-Zapico, S.1    Rodriguez-Blanco, J.2    Garcia-Santos, G.3
  • 11
    • 72949118848 scopus 로고    scopus 로고
    • Melatonin sensitizes human malignant glioma cells against TRAIL-induced cell death
    • Martin V, Garcia-Santos G, Rodriguez-Blanco J, et al., Melatonin sensitizes human malignant glioma cells against TRAIL-induced cell death. Cancer Lett 2010; 287: 216-223.
    • (2010) Cancer Lett , vol.287 , pp. 216-223
    • Martin, V.1    Garcia-Santos, G.2    Rodriguez-Blanco, J.3
  • 12
    • 67649970221 scopus 로고    scopus 로고
    • Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: Therapeutic implications for prostate cancer
    • Joo SS, Yoo YM,. Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer. J Pineal Res 2009; 47: 8-14.
    • (2009) J Pineal Res , vol.47 , pp. 8-14
    • Joo, S.S.1    Yoo, Y.M.2
  • 14
    • 0033561797 scopus 로고    scopus 로고
    • Deconstructing a disease: RARα, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
    • Melnick A, Licht JD,. Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood 1999; 93: 3167-3215. (Pubitemid 29220886)
    • (1999) Blood , vol.93 , Issue.10 , pp. 3167-3215
    • Melnick, A.1    Licht, J.D.2
  • 15
    • 0028820367 scopus 로고
    • Leukemia cell lines: In vitro models for the study of acute promyelocytic leukemia
    • Drexler HG, Quentmeier H, Macleod RA, et al., Leukemia cell lines: in vitro models for the study of acute promyelocytic leukemia. Leuk Res 1995; 19: 681-691.
    • (1995) Leuk Res , vol.19 , pp. 681-691
    • Drexler, H.G.1    Quentmeier, H.2    MacLeod, R.A.3
  • 16
    • 0042848523 scopus 로고    scopus 로고
    • Treatment of acute promyelocytic leukemia and other hematologic malignancies with arsenic trioxide: Review of clinical and basic studies
    • Liu P, Han ZC,. Treatment of acute promyelocytic leukemia and other hematologic malignancies with arsenic trioxide: review of clinical and basic studies. Int J Hematol 2003; 78: 32-39. (Pubitemid 36899899)
    • (2003) International Journal of Hematology , vol.78 , Issue.1 , pp. 32-39
    • Liu, P.1    Han, Z.C.2
  • 17
    • 0026647140 scopus 로고
    • The "retinoic acid syndrome" in acute promyelocytic leukemia
    • Frankel SR, Eardley A, Lauwers G, et al., The "retinoic acid syndrome" in acute promyelocytic leukemia. Ann Intern Med 1992; 117: 292-296.
    • (1992) Ann Intern Med , vol.117 , pp. 292-296
    • Frankel, S.R.1    Eardley, A.2    Lauwers, G.3
  • 18
    • 0031976484 scopus 로고    scopus 로고
    • Retinoic acid syndrome: Recognition, prevention and management
    • DOI 10.2165/00002018-199818040-00003
    • Fenaux P, De Botton S,. Retinoic acid syndrome. Recognition, prevention and management. Drug Saf 1998; 18: 273-279. (Pubitemid 28177291)
    • (1998) Drug Safety , vol.18 , Issue.4 , pp. 273-279
    • Fenaux, P.1    De Botton, S.2
  • 19
    • 0029819203 scopus 로고    scopus 로고
    • AIDA (all-trans retinoic acid + idarubicin) in newly diagnosed acute promyelocytic leukemia: A Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) pilot study
    • Avvisati G, Lo Coco F, Diverio D, et al., AIDA (all-trans retinoic acid + idarubicin) in newly diagnosed acute promyelocytic leukemia: a Gruppo Italiano Malattie Ematologiche Maligne dell'Adulto (GIMEMA) pilot study. Blood 1996; 88: 1390-1398. (Pubitemid 26276815)
    • (1996) Blood , vol.88 , Issue.4 , pp. 1390-1398
    • Avvisati, G.1    Lo Coco, F.2    Diverio, D.3    Falda, M.4    Ferrara, F.5    Lazzarino, M.6    Russo, D.7    Petti, M.C.8    Mandelli, F.9
  • 20
    • 64649083374 scopus 로고    scopus 로고
    • Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells
    • Bejarano I, Redondo PC, Espino J, et al., Melatonin induces mitochondrial-mediated apoptosis in human myeloid HL-60 cells. J Pineal Res 2009; 46: 392-400.
    • (2009) J Pineal Res , vol.46 , pp. 392-400
    • Bejarano, I.1    Redondo, P.C.2    Espino, J.3
  • 21
    • 33845949733 scopus 로고    scopus 로고
    • Dissecting the role of 5′-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase
    • DOI 10.1074/jbc.M606357200
    • Suter M, Riek U, Tuerk R, et al., Dissecting the role of 5′-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase. J Biol Chem 2006; 281: 32207-32216. (Pubitemid 46036775)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.43 , pp. 32207-32216
    • Suter, M.1    Riek, U.2    Tuerk, R.3    Schlattner, U.4    Wallimann, T.5    Neumann, D.6
  • 22
    • 0038199737 scopus 로고    scopus 로고
    • Management of cellular energy by the AMP-activated protein kinase system
    • DOI 10.1016/S0014-5793(03)00560-X
    • Hardie DG, Scott JW, Pan DA, et al., Management of cellular energy by the AMP-activated protein kinase system. FEBS Lett 2003; 546: 113-120. (Pubitemid 36782291)
    • (2003) FEBS Letters , vol.546 , Issue.1 , pp. 113-120
    • Hardie, D.G.1    Scott, J.W.2    Pan, D.A.3    Hudson, E.R.4
  • 23
    • 78650319600 scopus 로고    scopus 로고
    • Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition
    • Zhang WB, Wang Z, Su F, et al., Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition. J Biol Chem 2010; 285: 40461-40471.
    • (2010) J Biol Chem , vol.285 , pp. 40461-40471
    • Zhang, W.B.1    Wang, Z.2    Su, F.3
  • 24
    • 77955699748 scopus 로고    scopus 로고
    • Apoptotic effect of quercetin on HT-29 colon cancer cells via the AMPK signaling pathway
    • Kim HJ, Kim SK, Kim BS, et al., Apoptotic effect of quercetin on HT-29 colon cancer cells via the AMPK signaling pathway. J Agric Food Chem 2010; 58: 8643-8650.
    • (2010) J Agric Food Chem , vol.58 , pp. 8643-8650
    • Kim, H.J.1    Kim, S.K.2    Kim, B.S.3
  • 25
    • 74449087616 scopus 로고    scopus 로고
    • Activation of the AMP-activated protein kinase-p38 MAP kinase pathway mediates apoptosis induced by conjugated linoleic acid in p53-mutant mouse mammary tumor cells
    • Hsu YC, Meng X, Ou L, et al., Activation of the AMP-activated protein kinase-p38 MAP kinase pathway mediates apoptosis induced by conjugated linoleic acid in p53-mutant mouse mammary tumor cells. Cell Signal 2010; 22: 590-599.
    • (2010) Cell Signal , vol.22 , pp. 590-599
    • Hsu, Y.C.1    Meng, X.2    Ou, L.3
  • 26
    • 14244254386 scopus 로고    scopus 로고
    • Role of Chk1 and Chk2 in Ara-C-induced differentiation of human leukemia K562 cells
    • DOI 10.1111/j.1365-2443.2005.00821.x
    • Takagaki K, Katsuma S, Kaminishi Y, et al., Role of Chk1 and Chk2 in Ara-C-induced differentiation of human leukemia K562 cells. Genes Cells 2005; 10: 97-106. (Pubitemid 40287513)
    • (2005) Genes to Cells , vol.10 , Issue.2 , pp. 97-106
    • Takagaki, K.1    Katsuma, S.2    Kaminishi, Y.3    Horio, T.4    Tanaka, T.5    Ohgi, T.6    Yano, J.7
  • 27
    • 18144434267 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling: Cell cycle arrest versus apoptosis
    • DOI 10.1016/S0300-483X(02)00460-2, PII S0300483X02004602
    • Pietenpol JA, Stewart ZA,. Cell cycle checkpoint signaling: cell cycle arrest versus apoptosis. Toxicology 2002; 182: 475-481. (Pubitemid 36015741)
    • (2002) Toxicology , vol.181-182 , pp. 475-481
    • Pietenpol, J.A.1    Stewart, Z.A.2
  • 28
    • 0038418869 scopus 로고    scopus 로고
    • Chk1 and Chk2 kinases in checkpoint control and cancer
    • DOI 10.1016/S1535-6108(03)00110-7, PII S1535610803001107
    • Bartek J, Lukas J,. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 2003; 3: 421-429. (Pubitemid 38340288)
    • (2003) Cancer Cell , vol.3 , Issue.5 , pp. 421-429
    • Bartek, J.1    Lukas, J.2
  • 29
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • DOI 10.1101/gad.914401
    • Abraham RT,. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 2001; 15: 2177-2196. (Pubitemid 32843830)
    • (2001) Genes and Development , vol.15 , Issue.17 , pp. 2177-2196
    • Abraham, R.T.1
  • 30
    • 10844237358 scopus 로고    scopus 로고
    • Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing radiation
    • DOI 10.1158/0008-5472.CAN-04-2434
    • Syljuasen RG, Sorensen CS, Nylandsted J, et al., Inhibition of Chk1 by CEP-3891 accelerates mitotic nuclear fragmentation in response to ionizing Radiation. Cancer Res 2004; 64: 9035-9040. (Pubitemid 39665514)
    • (2004) Cancer Research , vol.64 , Issue.24 , pp. 9035-9040
    • Syljuasen, R.G.1    Sorensen, C.S.2    Nylandsted, J.3    Lukas, C.4    Lukas, J.5    Bartek, J.6
  • 31
    • 20544435456 scopus 로고    scopus 로고
    • Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage
    • DOI 10.1016/j.bbrc.2005.05.126, PII S0006291X05011241
    • Chen C, Shimizu S, Tsujimoto Y, et al., Chk2 regulates transcription-independent p53-mediated apoptosis in response to DNA damage. Biochem Biophys Res Commun 2005; 333: 427-431. (Pubitemid 40848308)
    • (2005) Biochemical and Biophysical Research Communications , vol.333 , Issue.2 , pp. 427-431
    • Chen, C.1    Shimizu, S.2    Tsujimoto, Y.3    Motoyama, N.4
  • 32
    • 77958480403 scopus 로고    scopus 로고
    • Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo
    • Niida H, Murata K, Shimada M, et al., Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo. EMBO J 2010; 29: 3558-3570.
    • (2010) EMBO J , vol.29 , pp. 3558-3570
    • Niida, H.1    Murata, K.2    Shimada, M.3
  • 33
    • 77957933561 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2-dependent survivin mediates decursin-induced apoptosis in human KBM-5 myeloid leukemia cells
    • Ahn Q, Jeong SJ, Lee HJ, et al., Inhibition of cyclooxygenase-2-dependent survivin mediates decursin-induced apoptosis in human KBM-5 myeloid leukemia cells. Cancer Lett 2010; 298: 212-221.
    • (2010) Cancer Lett , vol.298 , pp. 212-221
    • Ahn, Q.1    Jeong, S.J.2    Lee, H.J.3
  • 34
    • 78249235878 scopus 로고    scopus 로고
    • Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway
    • Won SH, Lee HJ, Jeong SJ, et al., Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway. Biol Pharm Bull 2010; 33: 1828-1834.
    • (2010) Biol Pharm Bull , vol.33 , pp. 1828-1834
    • Won, S.H.1    Lee, H.J.2    Jeong, S.J.3
  • 35
    • 0032610936 scopus 로고    scopus 로고
    • Apoptosis. Molecules and mechanisms
    • Konopleva M, Zhao S, Xie Z, et al., Apoptosis. Molecules and mechanisms. Adv Exp Med Biol 1999; 457: 217-236.
    • (1999) Adv Exp Med Biol , vol.457 , pp. 217-236
    • Konopleva, M.1    Zhao, S.2    Xie, Z.3
  • 36
    • 0001483546 scopus 로고
    • Acute promyelocytic leukemia
    • Hillestad LK,. Acute promyelocytic leukemia. Acta Med Scand 1957; 159: 189-194.
    • (1957) Acta Med Scand , vol.159 , pp. 189-194
    • Hillestad, L.K.1
  • 37
    • 41949111045 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: From highly fatal to highly curable
    • Wang ZY, Chen Z,. Acute promyelocytic leukemia: from highly fatal to highly curable. Blood 2008; 111: 2505-2515.
    • (2008) Blood , vol.111 , pp. 2505-2515
    • Wang, Z.Y.1    Chen, Z.2
  • 40
    • 33846919919 scopus 로고    scopus 로고
    • Inhibition of proliferation and induction of apoptosis by melatonin in human myeloid HL-60 cells
    • DOI 10.1111/j.1600-079X.2006.00392.x
    • Rubio S, Estevez F, Cabrera J, et al., Inhibition of proliferation and induction of apoptosis by melatonin in human myeloid HL-60 cells. J Pineal Res 2007; 42: 131-138. (Pubitemid 46233058)
    • (2007) Journal of Pineal Research , vol.42 , Issue.2 , pp. 131-138
    • Rubio, S.1    Estevez, F.2    Cabrera, J.3    Reiter, R.J.4    Loro, J.5    Quintana, J.6
  • 41
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis. An overview of cell death
    • Majno G, Joris I,. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995; 146: 3-15.
    • (1995) Am J Pathol , vol.146 , pp. 3-15
    • Majno, G.1    Joris, I.2
  • 42
    • 77955917717 scopus 로고    scopus 로고
    • Ionizing radiation activates AMP-activated kinase (AMPK): A target for radiosensitization of human cancer cells
    • Sanli T, Rashid A, Liu C, et al., Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells. Int J Radiat Oncol Biol Phys 2010; 78: 221-229.
    • (2010) Int J Radiat Oncol Biol Phys , vol.78 , pp. 221-229
    • Sanli, T.1    Rashid, A.2    Liu, C.3
  • 43
    • 44649104448 scopus 로고    scopus 로고
    • Targeting AMPK: A new therapeutic opportunity in breast cancer
    • Hadad SM, Fleming S, Thompson AM,. Targeting AMPK: a new therapeutic opportunity in breast cancer. Crit Rev Oncol Hematol 2008; 67: 1-7.
    • (2008) Crit Rev Oncol Hematol , vol.67 , pp. 1-7
    • Hadad, S.M.1    Fleming, S.2    Thompson, A.M.3
  • 44
    • 75349099919 scopus 로고    scopus 로고
    • Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer
    • Fogarty S, Hardie DG,. Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer. Biochim Biophys Acta 2010; 1804: 581-591.
    • (2010) Biochim Biophys Acta , vol.1804 , pp. 581-591
    • Fogarty, S.1    Hardie, D.G.2
  • 45
    • 77955923866 scopus 로고    scopus 로고
    • Metformin: Taking away the candy for cancer?
    • Jalving M, Gietema JA, Lefrandt JD, et al., Metformin: taking away the candy for cancer? Eur J Cancer 2010; 46: 2369-2380.
    • (2010) Eur J Cancer , vol.46 , pp. 2369-2380
    • Jalving, M.1    Gietema, J.A.2    Lefrandt, J.D.3
  • 46
    • 78149250620 scopus 로고    scopus 로고
    • AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through the activation of the pro-apoptotic BH3-only protein BMF
    • Kilbride SM, Farrelly AM, Bonner C, et al., AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through the activation of the pro-apoptotic BH3-only protein BMF. J Biol Chem 2010; 285: 36199-36206.
    • (2010) J Biol Chem , vol.285 , pp. 36199-36206
    • Kilbride, S.M.1    Farrelly, A.M.2    Bonner, C.3
  • 47
    • 78651509603 scopus 로고    scopus 로고
    • Melatonin Potentiates the Neuroprotective Properties of Resveratrol Against Beta-Amyloid-Induced Neurodegeneration by Modulating AMP-Activated Protein Kinase Pathways
    • Kwon KJ, Kim HJ, Shin CY, et al., Melatonin Potentiates the Neuroprotective Properties of Resveratrol Against Beta-Amyloid-Induced Neurodegeneration by Modulating AMP-Activated Protein Kinase Pathways. J Clin Neurol 2010; 6: 127-137.
    • (2010) J Clin Neurol , vol.6 , pp. 127-137
    • Kwon, K.J.1    Kim, H.J.2    Shin, C.Y.3
  • 50
  • 52
    • 74949120032 scopus 로고    scopus 로고
    • Targeting the checkpoint kinase Chk1 in cancer therapy
    • Merry C, Fu K, Wang J, et al., Targeting the checkpoint kinase Chk1 in cancer therapy. Cell Cycle 2010; 9: 279-283.
    • (2010) Cell Cycle , vol.9 , pp. 279-283
    • Merry, C.1    Fu, K.2    Wang, J.3
  • 53
    • 77949414415 scopus 로고    scopus 로고
    • Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors
    • PIRES IM, WARD TH, DIVE C,. Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors. Br J Pharmacol 2010; 159: 1326-1338.
    • (2010) Br J Pharmacol , vol.159 , pp. 1326-1338
    • Pires, I.M.1    Ward, T.H.2    Dive, C.3
  • 55
    • 4644281946 scopus 로고    scopus 로고
    • Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy
    • DOI 10.1038/sj.onc.1207860
    • Vogel C, Kienitz A, Hofmann I, et al., Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy. Oncogene 2004; 23: 6845-6853. (Pubitemid 39279985)
    • (2004) Oncogene , vol.23 , Issue.41 , pp. 6845-6853
    • Vogel, C.1    Kienitz, A.2    Hofmann, I.3    Muller, R.4    Bastians, H.5


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