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Volumn 6, Issue 5, 2009, Pages 327-334

NF-κB signaling pathway, inflammation and colorectal cancer

Author keywords

Colorectal cancer; Inflammation; NF B

Indexed keywords

ACETYLSALICYLIC ACID; ANTINEOPLASTIC AGENT; CELL PROTEIN; CHEMOKINE; CURCUMIN; CYCLIN D1; CYCLOOXYGENASE 2; CYTOKINE; GELATINASE B; GINSENG EXTRACT; GREEN TEA EXTRACT; I KAPPA B; I KAPPA B KINASE BETA INHIBITOR; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; METHOTREXATE; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEASOME INHIBITOR; RESVERATROL; SALAZOSULFAPYRIDINE; UNCLASSIFIED DRUG; VASCULOTROPIN; APOPTOSIS REGULATORY PROTEIN; PROTEIN SUBUNIT; RECOMBINANT CYTOKINE;

EID: 70350764831     PISSN: 10078738     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (364)

References (99)
  • 1
    • 34248157118 scopus 로고    scopus 로고
    • Effect of aspirin on long-term risk of colorectal cancer: Consistent evidence from randomised and observational studies
    • DOI 10.1016/S0140-6736(07)60747-8, PII S0140673607607478
    • Flossmann E, Rothwell PM. Effect of aspirin on long-term risk of colorectal cancer: consistent evidence from randomised and observational studies. Lancet. 2007;369:1603-1613. (Pubitemid 46710123)
    • (2007) Lancet , vol.369 , Issue.9573 , pp. 1603-1613
    • Flossmann, E.1    Rothwell, P.M.2
  • 2
    • 34249673868 scopus 로고    scopus 로고
    • Aspirin and the risk of colorectal cancer in relation to the expression of COX-2
    • DOI 10.1056/NEJMoa067208
    • Chan AT, Ogino S, Fuchs CS. Aspirin and the risk of colorectal cancer in relation to the expression of COX-2. N Engl J Med. 2007;356:2131-2142. (Pubitemid 47010839)
    • (2007) New England Journal of Medicine , vol.356 , Issue.21 , pp. 2131-2142
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 3
    • 20444441548 scopus 로고    scopus 로고
    • Cancer: Inflammation by remote control
    • Mantovani A. Cancer: inflammation by remote control. Nature. 2005;435:752-753.
    • (2005) Nature , vol.435 , pp. 752-753
    • Mantovani, A.1
  • 4
    • 31344466956 scopus 로고    scopus 로고
    • Chronic inflammation, immunosuppression and cancer: New insights and outlook
    • DOI 10.1016/j.semcancer.2005.12.002, PII S1044579X05000805, The Inflamation-Cancer Linkage: A Double-Edged Sword
    • Baniyash M. Chronic inflammation, immunosuppression and cancer: new insights and outlook. Semin Cancer Biol. 2006; 16:80-88. (Pubitemid 43139712)
    • (2006) Seminars in Cancer Biology , vol.16 , Issue.1 , pp. 80-88
    • Baniyash, M.1
  • 5
    • 35148874235 scopus 로고    scopus 로고
    • Inflammation and cancer: A double-edged sword
    • Hagemann T, Balkwill F, Lawrence T. Inflammation and cancer: a double-edged sword. Cancer Cell. 2007;12:300-301.
    • (2007) Cancer Cell , vol.12 , pp. 300-301
    • Hagemann, T.1    Balkwill, F.2    Lawrence, T.3
  • 7
    • 4043088499 scopus 로고    scopus 로고
    • IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • DOI 10.1016/j.cell.2004.07.013, PII S0092867404006713
    • Greten FR, Eckmann L, Greten TF, et al. IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell. 2004;118:285-296. (Pubitemid 39061110)
    • (2004) Cell , vol.118 , Issue.3 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3    Park, J.M.4    Li, Z.-W.5    Egan, L.J.6    Kagnoff, M.F.7    Karin, M.8
  • 9
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-κB in cancer development and progression
    • DOI 10.1038/nature04870, PII NATURE04870
    • Karin M. Nuclear factor-κB in cancer development and progression. Nature. 2006;441:431-436. (Pubitemid 44050137)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 431-436
    • Karin, M.1
  • 10
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-κB signaling: Balancing life and death - A new approach to cancer therapy
    • Luo JL, Kamata H, Karin M. IKK/NF-κB signaling: balancing life and death - a new approach to cancer therapy. J Clin Invest. 2005;115:2625-2632.
    • (2005) J Clin Invest , vol.115 , pp. 2625-2632
    • Luo, J.L.1    Kamata, H.2    Karin, M.3
  • 11
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: The control of NF-κB activity
    • Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-κB activity. Annu Rev Immunol. 2000;18:621-663.
    • (2000) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 12
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Hayden MS, Ghosh S. Signaling to NF-κB. Genes Dev. 2004;18:2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 13
    • 0041830469 scopus 로고    scopus 로고
    • Annual report to the nation on the status of cancer, 1975-2000, featuring the uses of surveillance data for cancer prevention and control
    • Weir HK, Thun MJ, Hankey BF, et al. Annual report to the nation on the status of cancer, 1975-2000, featuring the uses of surveillance data for cancer prevention and control. J Natl Cancer Inst. 2003;95:1276-1299.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1276-1299
    • Weir, H.K.1    Thun, M.J.2    Hankey, B.F.3
  • 14
    • 58149202128 scopus 로고    scopus 로고
    • Is NF-κB a good target for cancer therapy? Hopes and pitfalls
    • Baud V, Karin M. Is NF-κB a good target for cancer therapy? Hopes and pitfalls. Nat Rev Drug Discov. 2009;8:33-40.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 33-40
    • Baud, V.1    Karin, M.2
  • 15
    • 34250898562 scopus 로고    scopus 로고
    • NF-κB as a potential molecular target for cancer therapy
    • Lee CH, Jeon YT, Kim SH, Song YS. NF-κB as a potential molecular target for cancer therapy. Biofactors. 2007;29:19-35. (Pubitemid 46985299)
    • (2007) BioFactors , vol.29 , Issue.1 , pp. 19-35
    • Lee, C.H.1    Jeon, Y.-T.2    Kim, S.-H.3    Song, Y.-S.4
  • 16
    • 54949147176 scopus 로고    scopus 로고
    • New regulators of NF-κB in inflammation
    • Ghosh S, Hayden MS. New regulators of NF-κB in inflammation. Nat Rev Immunol. 2008;8:837-848.
    • (2008) Nat Rev Immunol , vol.8 , pp. 837-848
    • Ghosh, S.1    Hayden, M.S.2
  • 17
    • 0029874138 scopus 로고    scopus 로고
    • The NF-κB and IκB proteins: New discoveries and insights
    • Baldwin AS, Jr. The NF-κB and IκB proteins: new discoveries and insights. Annu Rev Immunol. 1996;14:649-683.
    • (1996) Annu Rev Immunol , vol.14 , pp. 649-683
    • Baldwin Jr., A.S.1
  • 18
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-κB puzzle
    • Ghosh S, Karin M. Missing pieces in the NF-κB puzzle. Cell. 2002;109 Suppl:S81-96.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Ghosh, S.1    Karin, M.2
  • 19
    • 0031897632 scopus 로고    scopus 로고
    • NF-κB and rel proteins: Evolutionarily conserved mediators of immune responses
    • DOI 10.1146/annurev.immunol.16.1.225
    • Ghosh S, May MJ, Kopp EB. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol. 1998;16:225-260. (Pubitemid 28183365)
    • (1998) Annual Review of Immunology , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 20
    • 0034745021 scopus 로고    scopus 로고
    • IKKβ is essential for protecting T cells from TNFα-induced apoptosis
    • DOI 10.1016/S1074-7613(01)00104-2
    • Senftleben U, Li ZW, Baud V, Karin M. IKKβ is essential for protecting T cells from TNFα-induced apoptosis. Immunity. 2001;14:217-230. (Pubitemid 32289287)
    • (2001) Immunity , vol.14 , Issue.3 , pp. 217-230
    • Senftleben, U.1    Li, Z.-W.2    Baud, V.3    Karin, M.4
  • 21
    • 0036009115 scopus 로고    scopus 로고
    • NF-κB at the crossroads of life and death
    • Karin M, Lin A. NF-κB at the crossroads of life and death. Nat Immunol. 2002;3:221-227.
    • (2002) Nat Immunol , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 22
    • 0034745420 scopus 로고    scopus 로고
    • NF-κB-inducing kinase regulates the processing of NF-κB2 p100
    • DOI 10.1016/S1097-2765(01)00187-3
    • Xiao G, Harhaj EW, Sun SC. NF-κB-inducing kinase regulates the processing of NF-κB2 p100. Mol Cell. 2001;7:401-409. (Pubitemid 32206507)
    • (2001) Molecular Cell , vol.7 , Issue.2 , pp. 401-409
    • Xiao, G.1    Harhaj, E.W.2    Sun, S.-C.3
  • 23
    • 65549153680 scopus 로고    scopus 로고
    • META060 inhibits multiple kinases in the NF-κB pathway and suppresses LPS - Mediated inflammation in vitro and ex vivo
    • Desai A, Konda VR, Darland G, et al. META060 inhibits multiple kinases in the NF-κB pathway and suppresses LPS - mediated inflammation in vitro and ex vivo. Inflamm Res. 2009;58:229-234.
    • (2009) Inflamm Res , vol.58 , pp. 229-234
    • Desai, A.1    Konda, V.R.2    Darland, G.3
  • 26
    • 38849199203 scopus 로고    scopus 로고
    • Shared principles in NF-κB signaling
    • Hayden MS, Ghosh S. Shared principles in NF-κB signaling. Cell. 2008;132:344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 28
    • 0035444539 scopus 로고    scopus 로고
    • Signal transduction by tumor necrosis factor and its relatives
    • DOI 10.1016/S0962-8924(01)02064-5, PII S0962892401020645
    • Baud V, Karin M. Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol. 2001;11:372-377. (Pubitemid 32900529)
    • (2001) Trends in Cell Biology , vol.11 , Issue.9 , pp. 372-377
    • Baud, V.1    Karin, M.2
  • 29
    • 2342464085 scopus 로고    scopus 로고
    • The two NF-κB activation pathways and their role in innate and adaptive immunity
    • Bonizzi G, Karin M. The two NF-κB activation pathways and their role in innate and adaptive immunity. Trends Immunol. 2004;25:280-288.
    • (2004) Trends Immunol , vol.25 , pp. 280-288
    • Bonizzi, G.1    Karin, M.2
  • 30
    • 0037931474 scopus 로고    scopus 로고
    • RelB/p50 dimers are differentially regulated by tumor necrosis factor-α and lymphotoxin-β receptor activation. Critical roles for p100
    • DOI 10.1074/jbc.M300106200
    • Derudder E, Dejardin E, Pritchard LL, Green DR, Korner M, Baud V. RelB/p50 dimers are differentially regulated by tumor necrosis factor-α and lymphotoxin-β receptor activation: critical roles for p100. J Biol Chem. 2003;278:23278-23284. (Pubitemid 36830141)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.26 , pp. 23278-23284
    • Derudder, E.1    Dejardin, E.2    Pritchard, L.L.3    Green, D.R.4    Korner, M.5    Baud, V.6
  • 32
    • 33749265867 scopus 로고    scopus 로고
    • The alternative NF-κB pathway from biochemistry to biology: Pitfalls and promises for future drug development
    • DOI 10.1016/j.bcp.2006.08.007, PII S0006295206005004
    • Dejardin E. The alternative NF-κB pathway from biochemistry to biology: pitfalls and promises for future drug development. Biochem Pharmacol. 2006;72:1161-1179. (Pubitemid 44479741)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.9 SPEC. ISS , pp. 1161-1179
    • Dejardin, E.1
  • 36
    • 0242298578 scopus 로고    scopus 로고
    • CK2 is a C-terminal IκB kinase responsible for NF-κB activation during the UV response
    • DOI 10.1016/S1097-2765(03)00358-7
    • Kato T, Jr, Delhase M, Hoffmann A, Karin M. CK2 is a C-terminal IκB kinase responsible for NF-κB activation during the UV response. Mol Cell. 2003;12:829-839. (Pubitemid 37352777)
    • (2003) Molecular Cell , vol.12 , Issue.4 , pp. 829-839
    • Kato Jr., T.1    Delhase, M.2    Hoffmann, A.3    Karin, M.4
  • 38
    • 0037202937 scopus 로고    scopus 로고
    • Dual effect of oxidative stress on NF-κB activation in HeLa cells
    • Byun MS, Jeon KI, Choi JW, Shim JY, Jue DM. Dual effect of oxidative stress on NF-κB activation in HeLa cells. Exp Mol Med. 2002;34:332-339.
    • (2002) Exp Mol Med , vol.34 , pp. 332-339
    • Byun, M.S.1    Jeon, K.I.2    Choi, J.W.3    Shim, J.Y.4    Jue, D.M.5
  • 39
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet. 2001;357:539-545.
    • (2001) Lancet , vol.357 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 40
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2
  • 41
    • 0036779617 scopus 로고    scopus 로고
    • Anti-inflammatory lipid mediators and insights into the resolution of inflammation
    • Lawrence T, Willoughby DA, Gilroy DW. Anti-inflammatory lipid mediators and insights into the resolution of inflammation. Nat Rev Immunol. 2002;2:787-795.
    • (2002) Nat Rev Immunol , vol.2 , pp. 787-795
    • Lawrence, T.1    Willoughby, D.A.2    Gilroy, D.W.3
  • 42
    • 3543102542 scopus 로고    scopus 로고
    • Inflammation and necrosis promote tumour growth
    • Vakkila J, Lotze MT. Inflammation and necrosis promote tumour growth. Nat Rev Immunol. 2004;4:641-648. (Pubitemid 39025049)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.8 , pp. 641-648
    • Vakkila, J.1    Lotze, M.T.2
  • 43
    • 58649108302 scopus 로고    scopus 로고
    • IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
    • Grivennikov S, Karin E, Terzic J, et al. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell. 2009;15:103-113.
    • (2009) Cancer Cell , vol.15 , pp. 103-113
    • Grivennikov, S.1    Karin, E.2    Terzic, J.3
  • 44
    • 33645508531 scopus 로고    scopus 로고
    • Chronic inflammation: A common and important factor in the pathogenesis of neoplasia
    • Schottenfeld D, Beebe-Dimmer J. Chronic inflammation: a common and important factor in the pathogenesis of neoplasia. CA Cancer J Clin. 2006;56:69-83.
    • (2006) CA Cancer J Clin , vol.56 , pp. 69-83
    • Schottenfeld, D.1    Beebe-Dimmer, J.2
  • 45
    • 17444425273 scopus 로고    scopus 로고
    • Advances in cancer epidemiology: Understanding causal mechanisms and the evidence for implementing interventions
    • DOI 10.1146/annurev.publhealth.26.021304.144402
    • Schottenfeld D, Beebe-Dimmer JL. Advances in cancer epidemiology: understanding causal mechanisms and the evidence for implementing interventions. Annu Rev Public Health. 2005;26:37-60. (Pubitemid 40547375)
    • (2005) Annual Review of Public Health , vol.26 , pp. 37-60
    • Schottenfeld, D.1    Beebe-Dimmer, J.L.2
  • 47
    • 0035139943 scopus 로고    scopus 로고
    • Hostile takeovers: Viral appropriation of the NF-κB pathway
    • Hiscott J, Kwon H, Genin P. Hostile takeovers: viral appropriation of the NF-κB pathway. J Clin Invest. 2001;107:143-151. (Pubitemid 32096827)
    • (2001) Journal of Clinical Investigation , vol.107 , Issue.2 , pp. 143-151
    • Hiscott, J.1    Kwon, H.2    Genin, P.3
  • 48
    • 3042579870 scopus 로고    scopus 로고
    • Evaluation of nuclear factor-κB, urokinase-type plasminogen activator, and HBx and their clinicopathological significance in hepatocellular carcinoma
    • Chan CF, Yau TO, Jin DY, Wong CM, Fan ST, Ng IO. Evaluation of nuclear factor-κB, urokinase-type plasminogen activator, and HBx and their clinicopathological significance in hepatocellular carcinoma. Clin Cancer Res. 2004;10:4140-4149.
    • (2004) Clin Cancer Res , vol.10 , pp. 4140-4149
    • Chan, C.F.1    Yau, T.O.2    Jin, D.Y.3    Wong, C.M.4    Fan, S.T.5    Ng, I.O.6
  • 49
    • 0346258152 scopus 로고    scopus 로고
    • Human papillomavirus and oral cancer: The international agency for research on cancer multicenter study
    • Herrero R, Castellsague X, Pawlita M, et al. Human papillomavirus and oral cancer: the international agency for research on cancer multicenter study. J Natl Cancer Inst. 2003;95:1772-1783.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 1772-1783
    • Herrero, R.1    Castellsague, X.2    Pawlita, M.3
  • 53
    • 60549089851 scopus 로고    scopus 로고
    • Markers of inflammation and risk of ovarian cancer in Los Angeles County
    • Wu AH, Pearce CL, Tseng CC, Templeman C, Pike MC. Markers of inflammation and risk of ovarian cancer in Los Angeles County. Int J Cancer. 2009;124:1409-1415.
    • (2009) Int J Cancer , vol.124 , pp. 1409-1415
    • Wu, A.H.1    Pearce, C.L.2    Tseng, C.C.3    Templeman, C.4    Pike, M.C.5
  • 54
    • 0035080617 scopus 로고    scopus 로고
    • The risk of colorectal cancer in ulcerative colitis: A meta-analysis
    • DOI 10.1136/gut.48.4.526
    • Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut. 2001;48:526-535. (Pubitemid 32234798)
    • (2001) Gut , vol.48 , Issue.4 , pp. 526-535
    • Eaden, J.A.1    Abrams, K.R.2    Mayberry, J.F.3
  • 55
    • 0037357426 scopus 로고    scopus 로고
    • Oxidative stress and ulcerative colitis-associated carcinogenesis: Studies in humans and animal models
    • DOI 10.1093/carcin/24.3.353
    • Seril DN, Liao J, Yang GY, Yang CS. Oxidative stress and ulcerative colitis-associated carcinogenesis: studies in humans and animal models. Carcinogenesis. 2003;24:353-362. (Pubitemid 36432628)
    • (2003) Carcinogenesis , vol.24 , Issue.3 , pp. 353-362
    • Seril, D.N.1    Liao, J.2    Yang, G.-Y.3    Yang, C.S.4
  • 56
    • 46749127004 scopus 로고    scopus 로고
    • DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
    • Meira LB, Bugni JM, Green SL, et al. DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. J Clin Invest. 2008;118:2516-2525.
    • (2008) J Clin Invest , vol.118 , pp. 2516-2525
    • Meira, L.B.1    Bugni, J.M.2    Green, S.L.3
  • 57
    • 17444418692 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drugs and colorectal cancer prevention
    • Sangha S, Yao M, Wolfe MM. Non-steroidal anti-inflammatory drugs and colorectal cancer prevention. Postgrad Med J. 2005;81:223-227.
    • (2005) Postgrad Med J , vol.81 , pp. 223-227
    • Sangha, S.1    Yao, M.2    Wolfe, M.M.3
  • 58
    • 33746703295 scopus 로고    scopus 로고
    • Do older adults using NSAIDs have a reduced risk of colorectal cancer?
    • Hoffmeister M, Chang-Claude J, Brenner H. Do older adults using NSAIDs have a reduced risk of colorectal cancer? Drugs Aging. 2006;23:513-523.
    • (2006) Drugs Aging , vol.23 , pp. 513-523
    • Hoffmeister, M.1    Chang-Claude, J.2    Brenner, H.3
  • 61
    • 32944474237 scopus 로고    scopus 로고
    • Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer
    • DOI 10.1016/j.cell.2006.02.016, PII S0092867406001917
    • Karin M, Lawrence T, Nizet V. Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell. 2006;124:823-835. (Pubitemid 43261455)
    • (2006) Cell , vol.124 , Issue.4 , pp. 823-835
    • Karin, M.1    Lawrence, T.2    Nizet, V.3
  • 62
    • 34248141100 scopus 로고    scopus 로고
    • A cytokine-mediated link between innate immunity, inflammation, and cancer
    • DOI 10.1172/JCI31537
    • Lin WW, Karin M. A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest. 2007;117: 1175-1183. (Pubitemid 46718402)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1175-1183
    • Lin, W.-W.1    Karin, M.2
  • 63
    • 0036546501 scopus 로고    scopus 로고
    • NF-κB in cancer: From innocent bystander to major culprit
    • Karin M, Cao Y, Greten FR, Li ZW. NF-κB in cancer: from innocent bystander to major culprit. Nat Rev Cancer. 2002;2:301-310. (Pubitemid 37328783)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.4 , pp. 301-310
    • Karin, M.1    Cao, Y.2    Greten, F.R.3    Li, Z.-W.4
  • 64
    • 0036717195 scopus 로고    scopus 로고
    • NF-κB, chemokine gene transcription and tumour growth
    • DOI 10.1038/nri887
    • Richmond A. NF-κB, chemokine gene transcription and tumour growth. Nat Rev Immunol. 2002;2:664-674. (Pubitemid 37328724)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.9 , pp. 664-674
    • Richmond, A.1
  • 65
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 66
    • 1142274315 scopus 로고    scopus 로고
    • Apoptosis in cancer-implications for therapy
    • Schulze-Bergkamen H, Krammer PH. Apoptosis in cancer-implications for therapy. Semin Oncol. 2004;31:90-119.
    • (2004) Semin Oncol , vol.31 , pp. 90-119
    • Schulze-Bergkamen, H.1    Krammer, P.H.2
  • 67
    • 1642553460 scopus 로고    scopus 로고
    • To be, or not to be: NF-κB is the answer-role of Rel/NF-κB in the regulation of apoptosis
    • Kucharczak J, Simmons MJ, Fan Y, Gelinas C. To be, or not to be: NF-κB is the answer-role of Rel/NF-κB in the regulation of apoptosis. Oncogene. 2003;22:8961-8982.
    • (2003) Oncogene , vol.22 , pp. 8961-8982
    • Kucharczak, J.1    Simmons, M.J.2    Fan, Y.3    Gelinas, C.4
  • 68
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice
    • Neurath MF, Pettersson S, Meyer zum Buschenfelde KH, Strober W. Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-κB abrogates established experimental colitis in mice. Nat Med. 1996;2:998-1004.
    • (1996) Nat Med , vol.2 , pp. 998-1004
    • Neurath, M.F.1    Pettersson, S.2    Meyer Zum Buschenfelde, K.H.3    Strober, W.4
  • 73
    • 0032588186 scopus 로고    scopus 로고
    • NF-κB controls cell growth and differentiation through transcriptional regulation of cyclin D1
    • Guttridge DC, Albanese C, Reuther JY, Pestell RG, Baldwin AS, Jr. NF-κB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol Cell Biol. 1999;19:5785-5799.
    • (1999) Mol Cell Biol , vol.19 , pp. 5785-5799
    • Guttridge, D.C.1    Albanese, C.2    Reuther, J.Y.3    Pestell, R.G.4    Baldwin Jr., A.S.5
  • 74
    • 0033621956 scopus 로고    scopus 로고
    • The Rel/NF-κB family directly activates expression of the apoptosis inhibitor Bcl-x(L)
    • Chen C, Edelstein LC, Gelinas C. The Rel/NF-κB family directly activates expression of the apoptosis inhibitor Bcl-x(L). Mol Cell Biol. 2000;20:2687-2695.
    • (2000) Mol Cell Biol , vol.20 , pp. 2687-2695
    • Chen, C.1    Edelstein, L.C.2    Gelinas, C.3
  • 76
    • 38149140259 scopus 로고    scopus 로고
    • SmgGDS regulates cell proliferation, migration, and NF-κB transcriptional activity in non-small cell lung carcinoma
    • Tew GW, Lorimer EL, Berg TJ, Zhi H, Li R, Williams CL. SmgGDS regulates cell proliferation, migration, and NF-κB transcriptional activity in non-small cell lung carcinoma. J Biol Chem. 2008;283:963-976.
    • (2008) J Biol Chem , vol.283 , pp. 963-976
    • Tew, G.W.1    Lorimer, E.L.2    Berg, T.J.3    Zhi, H.4    Li, R.5    Williams, C.L.6
  • 77
    • 35948988561 scopus 로고    scopus 로고
    • Inactivation of NF-κB by 3,3′-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells
    • Rahman KM, Ali S, Aboukameel A, Sarkar SH, et al. Inactivation of NF-κB by 3,3′-diindolylmethane contributes to increased apoptosis induced by chemotherapeutic agent in breast cancer cells. Mol Cancer Ther. 2007;6:2757-2765.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2757-2765
    • Rahman, K.M.1    Ali, S.2    Aboukameel, A.3    Sarkar, S.H.4
  • 78
    • 4544224979 scopus 로고    scopus 로고
    • Inhibition of NF-κB in cancer cells converts inflammation- Induced tumor growth mediated by TNFα to TRAIL-mediated tumor regression
    • DOI 10.1016/j.ccr.2004.08.012, PII S153561080400217X
    • Luo JL, Maeda S, Hsu LC, Yagita H, Karin M. Inhibition of NF-κB in cancer cells converts inflammation-induced tumor growth mediated by TNFα to TRAIL-mediated tumor regression. Cancer Cell. 2004;6:297-305. (Pubitemid 39222042)
    • (2004) Cancer Cell , vol.6 , Issue.3 , pp. 297-305
    • Luo, J.-L.1    Maeda, S.2    Hsu, L.-C.3    Yagita, H.4    Karin, M.5
  • 79
    • 0035137882 scopus 로고    scopus 로고
    • Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB
    • Baldwin AS. Control of oncogenesis and cancer therapy resistance by the transcription factor NF-κB. J Clin Invest. 2001;107:241-246. (Pubitemid 32157954)
    • (2001) Journal of Clinical Investigation , vol.107 , Issue.3 , pp. 241-246
    • Baldwin, A.S.1
  • 80
    • 0035224563 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its role in neoplastic processes
    • Loch T, Michalski B, Mazurek U, Graniczka M. (Vascular endothelial growth factor (VEGF) and its role in neoplastic processes). Postepy Hig Med Dosw. 2001;55:257-274.
    • (2001) Postepy Hig Med Dosw , vol.55 , pp. 257-274
    • Loch, T.1    Michalski, B.2    Mazurek, U.3    Graniczka, M.4
  • 81
    • 0033623902 scopus 로고    scopus 로고
    • Nuclear factor-κB activity correlates with growth, angiogenesis, and metastasis of human melanoma cells in nude mice
    • Huang S, DeGuzman A, Bucana CD, Fidler IJ. Nuclear factor-κB activity correlates with growth, angiogenesis, and metastasis of human melanoma cells in nude mice. Clin Cancer Res. 2000;6:2573-2581. (Pubitemid 30399230)
    • (2000) Clinical Cancer Research , vol.6 , Issue.6 , pp. 2573-2581
    • Huang, S.1    Deguzman, A.2    Bucana, C.D.3    Fidler, I.J.4
  • 82
    • 0003504049 scopus 로고    scopus 로고
    • Cyclooxygenase regulates angiogenesis induced by colon cancer cells
    • DOI 10.1016/S0092-8674(00)81433-6
    • Tsujii M, Kawano S, Tsuji S, Sawaoka H, Hori M, DuBois RN. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell. 1998;93:705-716. (Pubitemid 28257578)
    • (1998) Cell , vol.93 , Issue.5 , pp. 705-716
    • Tsujii, M.1    Kawano, S.2    Tsuji, S.3    Sawaoka, H.4    Hori, M.5    Dubois, R.N.6
  • 83
    • 40249098050 scopus 로고    scopus 로고
    • A ginseng saponin metabolite suppresses tumor necrosis factor-α-promoted metastasis by suppressing nuclear factor-κB signaling in murine colon cancer cells
    • Choo MK, Sakurai H, Kim DH, Saiki I. A ginseng saponin metabolite suppresses tumor necrosis factor-α-promoted metastasis by suppressing nuclear factor-κB signaling in murine colon cancer cells. Oncol Rep. 2008;19:595-600.
    • (2008) Oncol Rep , vol.19 , pp. 595-600
    • Choo, M.K.1    Sakurai, H.2    Kim, D.H.3    Saiki, I.4
  • 84
    • 33750435582 scopus 로고    scopus 로고
    • NF-κB and the immune response
    • Hayden MS, West AP, Ghosh S. NF-κB and the immune response. Oncogene. 2006;25:6758-6780.
    • (2006) Oncogene , vol.25 , pp. 6758-6780
    • Hayden, M.S.1    West, A.P.2    Ghosh, S.3
  • 85
    • 16644395843 scopus 로고    scopus 로고
    • Blocking anti-apoptosis as a strategy for cancer chemotherapy: NF-κB as a target
    • Monks NR, Biswas DK, Pardee AB. Blocking anti-apoptosis as a strategy for cancer chemotherapy: NF-κB as a target. J Cell Biochem. 2004;92:646-650.
    • (2004) J Cell Biochem , vol.92 , pp. 646-650
    • Monks, N.R.1    Biswas, D.K.2    Pardee, A.B.3
  • 86
    • 1842607516 scopus 로고    scopus 로고
    • NF-κB in cancer - A friend turned foe
    • Ravi R, Bedi A. NF-κB in cancer - a friend turned foe. Drug Resist Updat. 2004;7:53-67.
    • (2004) Drug Resist Updat , vol.7 , pp. 53-67
    • Ravi, R.1    Bedi, A.2
  • 87
    • 0036964816 scopus 로고    scopus 로고
    • Chemopreventive agents induce suppression of nuclear factor-κB leading to chemosensitization
    • Bharti AC, Aggarwal BB. Chemopreventive agents induce suppression of nuclear factor-κB leading to chemosensitization. Ann N Y Acad Sci. 2002;973:392-395.
    • (2002) Ann N Y Acad Sci , vol.973 , pp. 392-395
    • Bharti, A.C.1    Aggarwal, B.B.2
  • 88
    • 0344825070 scopus 로고    scopus 로고
    • AS602868, a pharmacological inhibitor of IKK2, reveals the apoptotic potential of TNF-α in Jurkat leukemic cells
    • DOI 10.1038/sj.onc.1206963
    • Frelin C, Imbert V, Griessinger E, Loubat A, Dreano M, Peyron JF. AS602868, a pharmacological inhibitor of IKK2, reveals the apoptotic potential of TNF-α in Jurkat leukemic cells. Oncogene. 2003;22:8187-8194. (Pubitemid 37487309)
    • (2003) Oncogene , vol.22 , Issue.50 , pp. 8187-8194
    • Frelin, C.1    Imbert, V.2    Griessinger, E.3    Loubat, A.4    Dreano, M.5    Peyron, J.-F.6
  • 89
    • 19944427042 scopus 로고    scopus 로고
    • Targeting NF-κB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells
    • Frelin C, Imbert V, Griessinger E, et al. Targeting NF-κB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells. Blood. 2005;105:804-811.
    • (2005) Blood , vol.105 , pp. 804-811
    • Frelin, C.1    Imbert, V.2    Griessinger, E.3
  • 91
    • 0034322370 scopus 로고    scopus 로고
    • Suppression of NF-βB activity by sulfasalazine is mediated by direct inhibition of IκB kinases α and β
    • Weber CK, Liptay S, Wirth T, Adler G, Schmid RM. Suppression of NF-βB activity by sulfasalazine is mediated by direct inhibition of IκB kinases α and β. Gastroenterology. 2000;119:1209-1218.
    • (2000) Gastroenterology , vol.119 , pp. 1209-1218
    • Weber, C.K.1    Liptay, S.2    Wirth, T.3    Adler, G.4    Schmid, R.M.5
  • 92
    • 0035451439 scopus 로고    scopus 로고
    • Methotrexate suppresses NF-κB activation through inhibition of IκBα phosphorylation and degradation
    • Majumdar S, Aggarwal BB. Methotrexate suppresses NF-κB activation through inhibition of IκBα phosphorylation and degradation. J Immunol. 2001;167:2911-2920.
    • (2001) J Immunol , vol.167 , pp. 2911-2920
    • Majumdar, S.1    Aggarwal, B.B.2
  • 93
    • 6844240876 scopus 로고    scopus 로고
    • Use of aspirin and other nonsteroidal anti-inflammatory drugs and risk of esophageal and gastric cancer
    • Farrow DC, Vaughan TL, Hansten PD, et al. Use of aspirin and other nonsteroidal anti-inflammatory drugs and risk of esophageal and gastric cancer. Cancer Epidemiol Biomarkers Prev. 1998;7:97-102.
    • (1998) Cancer Epidemiol Biomarkers Prev , vol.7 , pp. 97-102
    • Farrow, D.C.1    Vaughan, T.L.2    Hansten, P.D.3
  • 94
    • 0032816236 scopus 로고    scopus 로고
    • Aspirin protects against gastric cancer: Results of a case-control study from Moscow, Russia
    • DOI 10.1002/(SICI)1097-0215(19990812)82:4<473::AID-IJC1>3.0.CO;2-K
    • Zaridze D, Borisova E, Maximovitch D, Chkhikvadze V. Aspirin protects against gastric cancer: results of a case-control study from Moscow, Russia. Int J Cancer. 1999;82:473-476. (Pubitemid 29343443)
    • (1999) International Journal of Cancer , vol.82 , Issue.4 , pp. 473-476
    • Zaridze, D.1    Borisova, E.2    Maximovitch, D.3    Chkhikvadze, V.4
  • 95
    • 43749098070 scopus 로고    scopus 로고
    • NF-κB and cancer-identifying targets and mechanisms
    • Naugler WE, Karin M. NF-κB and cancer-identifying targets and mechanisms. Curr Opin Genet Dev. 2008;18:19-26.
    • (2008) Curr Opin Genet Dev , vol.18 , pp. 19-26
    • Naugler, W.E.1    Karin, M.2
  • 96
    • 64549164046 scopus 로고    scopus 로고
    • Chemosensitization and immunosensitization of resistant cancer cells to apoptosis and inhibition of metastasis by the specific NF-κB inhibitor DHMEQ
    • Katsman A, Umezawa K, Bonavida B. Chemosensitization and immunosensitization of resistant cancer cells to apoptosis and inhibition of metastasis by the specific NF-κB inhibitor DHMEQ. Curr Pharm Des. 2009;15:792-808.
    • (2009) Curr Pharm Des , vol.15 , pp. 792-808
    • Katsman, A.1    Umezawa, K.2    Bonavida, B.3
  • 97
    • 53049107046 scopus 로고    scopus 로고
    • Terpenoids: Natural inhibitors of NF-κB signaling with anti-inflammatory and anticancer potential
    • Salminen A, Lehtonen M, Suuronen T, Kaarniranta K, Huuskonen J. Terpenoids: natural inhibitors of NF-κB signaling with anti-inflammatory and anticancer potential. Cell Mol Life Sci. 2008;65:2979-2999.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 2979-2999
    • Salminen, A.1    Lehtonen, M.2    Suuronen, T.3    Kaarniranta, K.4    Huuskonen, J.5
  • 98
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-κB system: A treasure trove for drug development
    • Karin M, Yamamoto Y, Wang QM. The IKK NF-κB system: a treasure trove for drug development. Nat Rev Drug Discov. 2004;3:17-26. (Pubitemid 38088695)
    • (2004) Nature Reviews Drug Discovery , vol.3 , Issue.1 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 99
    • 33746160746 scopus 로고    scopus 로고
    • Protein kinase casein kinase 2 mediates inhibitor-κB kinase and aberrant nuclear factor-κB activation by serum factor(s) in head and neck squamous carcinoma cells
    • DOI 10.1158/0008-5472.CAN-05-3758
    • Yu M, Yeh J, Van Waes C. Protein kinase casein kinase 2 mediates inhibitor-κB kinase and aberrant nuclear factor-κB activation by serum factor(s) in head and neck squamous carcinoma cells. Cancer Res. 2006;66:6722-6731. (Pubitemid 44085630)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6722-6731
    • Yu, M.1    Yeh, J.2    Van Waes, C.3


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