Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP- ribose) synthase in a carrageenan-induced model of local inflammation

European Journal of Pharmacology

Volumn 342, Issue 1, 1998, Pages 67-76

  Cuzzocrea, Salvatore ^a   Zingarelli, Basilia ^a   Gilad, Eli ^a   Hake, Paul ^a   Salzman, Andrew L ^a   Szabó, Csaba ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Apoptosis; DNA strand break; Neutrophil; Nitric oxide (NO)(i); Peroxynitrite

Indexed keywords

3 AMINOBENZAMIDE; 3 NITROTYROSINE; CARRAGEENAN; DNA; DRUG VEHICLE; ENZYME INHIBITOR; MYELOPEROXIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN RADICAL; PEROXYNITRITE; SODIUM CHLORIDE; TRYPAN BLUE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA STRAND BREAKAGE; DRUG EFFECT; INFLAMMATION; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAPLEURAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LEUKOCYTE MIGRATION INHIBITION; LUNG BIOPSY; LUNG INFILTRATE; LUNG INJURY; MONONUCLEAR CELL; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PLEURA FLUID; PLEURISY; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BENZAMIDES; CARRAGEENAN; ENZYME INHIBITORS; EXUDATES AND TRANSUDATES; IMMUNOHISTOCHEMISTRY; INFLAMMATION; NITRATES; NITRIC OXIDE SYNTHASE; NITRITES; PEROXIDASE; PLEURISY; POLY(ADP-RIBOSE) POLYMERASES; RATS;

EID: 0032545762     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01417-9     Document Type: Article

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