Melatonin represses oxidative stress-induced activation of the MAP kinase and mTOR signaling pathways in H4IIE hepatoma cells through inhibition of Ras

Journal of Pineal Research

Volumn 44, Issue 4, 2008, Pages 379-386

  Kimball, Scot R ^a   Abbas, Ahmed ^a,b   Jefferson, Leonard S ^a,b  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Akt; ERK1 2; MTOR; p38 MAP kinase; Reactive oxygen species

Indexed keywords

HYDROGEN PEROXIDE; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MELATONIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; RAS PROTEIN;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; HEPATOMA CELL; HORMONAL REGULATION; NONHUMAN; OXIDATIVE STRESS; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; CELL LINE, TUMOR; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HYDROGEN PEROXIDE; MELATONIN; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RAS PROTEINS; RATS; UP-REGULATION;

EID: 42249099251     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2007.00539.x     Document Type: Article

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