-
1
-
-
60649095658
-
Cyclic AMP produced inside mitochondria regulates oxidative phosphorylation
-
Acin-Perez R, Salazar E, Kamenetsky M, Buck J, Levin LR, Manfredi G. Cyclic AMP produced inside mitochondria regulates oxidative phosphorylation. Cell Metab 9: 265-276, 2009.
-
(2009)
Cell Metab
, vol.9
, pp. 265-276
-
-
Acin-Perez, R.1
Salazar, E.2
Kamenetsky, M.3
Buck, J.4
Levin, L.R.5
Manfredi, G.6
-
2
-
-
26444557412
-
The endocannabinoid system drives neural progenitor proliferation
-
Aguado T, Monory K, Palazuelos J, Stella N, Cravatt B, Lutz B, Marsicano G, Kokaia Z, Guzman M, Galve-Roperh I. The endocannabinoid system drives neural progenitor proliferation. FASEB J 19: 1704-1706, 2005.
-
(2005)
FASEB J
, vol.19
, pp. 1704-1706
-
-
Aguado, T.1
Monory, K.2
Palazuelos, J.3
Stella, N.4
Cravatt, B.5
Lutz, B.6
Marsicano, G.7
Kokaia, Z.8
Guzman, M.9
Galve-Roperh, I.10
-
3
-
-
34447618831
-
PPARs and their metabolic modulation: New mechanisms for transcriptional regulation?
-
Ahmed W, Ziouzenkova O, Brown J, Devchand P, Francis S, Kadakia M, Kanda T, Orasanu G, Sharlach M, Zandbergen F, Plutzky J. PPARs and their metabolic modulation: new mechanisms for transcriptional regulation? J Intern Med 262: 184-198, 2007.
-
(2007)
J Intern Med
, vol.262
, pp. 184-198
-
-
Ahmed, W.1
Ziouzenkova, O.2
Brown, J.3
Devchand, P.4
Francis, S.5
Kadakia, M.6
Kanda, T.7
Orasanu, G.8
Sharlach, M.9
Zandbergen, F.10
Plutzky, J.11
-
4
-
-
35348942818
-
Cannabinoid receptor agonists are mitochondrial inhibitors: A unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death
-
Athanasiou A, Clarke AB, Turner AE, Kumaran NM, Vakilpour S, Smith PA, Bagiokou D, Bradshaw TD, Westwell AD, Fang L, Lobo DN, Constantinescu CS, Calabrese V, Loesch A, Alexander SP, Clothier RH, Kendall DA, Bates TE. Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death. Biochem Biophys Res Commun 364: 131-137, 2007.
-
(2007)
Biochem Biophys Res Commun
, vol.364
, pp. 131-137
-
-
Athanasiou, A.1
Clarke, A.B.2
Turner, A.E.3
Kumaran, N.M.4
Vakilpour, S.5
Smith, P.A.6
Bagiokou, D.7
Bradshaw, T.D.8
Westwell, A.D.9
Fang, L.10
Lobo, D.N.11
Constantinescu, C.S.12
Calabrese, V.13
Loesch, A.14
Alexander, S.P.15
Clothier, R.H.16
Kendall, D.A.17
Bates, T.E.18
-
5
-
-
33846281508
-
Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: How vanilloids cause non-vanilloid receptor mediated cell death
-
Athanasiou A, Smith PA, Vakilpour S, Kumaran NM, Turner AE, Bagiokou D, Layfield R, Ray DE, Westwell AD, Alexander SP, Kendall DA, Lobo DN, Watson SA, Lophatanon A, Muir KA, Guo DA, Bates TE. Vanilloid receptor agonists and antagonists are mitochondrial inhibitors: how vanilloids cause non-vanilloid receptor mediated cell death. Biochem Biophys Res Commun 354: 50-55, 2007.
-
(2007)
Biochem Biophys Res Commun
, vol.354
, pp. 50-55
-
-
Athanasiou, A.1
Smith, P.A.2
Vakilpour, S.3
Kumaran, N.M.4
Turner, A.E.5
Bagiokou, D.6
Layfield, R.7
Ray, D.E.8
Westwell, A.D.9
Alexander, S.P.10
Kendall, D.A.11
Lobo, D.N.12
Watson, S.A.13
Lophatanon, A.14
Muir, K.A.15
Guo, D.A.16
Bates, T.E.17
-
6
-
-
79251564054
-
Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects
-
Banni S, Carta G, Murru E, Cordeddu L, Giordano E, Sirigu AR, Berge K, Vik H, Maki KC, Di Marzo V, Griinari M. Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects. Nutr Metab (Lond) 8: 7, 2011.
-
(2011)
Nutr Metab (Lond)
, vol.8
, pp. 7
-
-
Banni, S.1
Carta, G.2
Murru, E.3
Cordeddu, L.4
Giordano, E.5
Sirigu, A.R.6
Berge, K.7
Vik, H.8
Maki, K.C.9
Di Marzo, V.10
Griinari, M.11
-
7
-
-
67749139564
-
Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats
-
Batetta B, Griinari M, Carta G, Murru E, Ligresti A, Cordeddu L, Giordano E, Sanna F, Bisogno T, Uda S, Collu M, Bruheim I, Di Marzo V, Banni S. Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats. J Nutr 139: 1495-1501, 2009.
-
(2009)
J Nutr
, vol.139
, pp. 1495-1501
-
-
Batetta, B.1
Griinari, M.2
Carta, G.3
Murru, E.4
Ligresti, A.5
Cordeddu, L.6
Giordano, E.7
Sanna, F.8
Bisogno, T.9
Uda, S.10
Collu, M.11
Bruheim, I.12
Di Marzo, V.13
Banni, S.14
-
8
-
-
84859208807
-
Mitochondrial CB(1) receptors regulate neuronal energy metabolism
-
Benard G, Massa F, Puente N, Lourenco J, Bellocchio L, Soria-Gomez E, Matias I, Delamarre A, Metna-Laurent M, Cannich A, Hebert-Chatelain E, Mulle C, Ortega-Gutierrez S, Martin-Fontecha M, Klugmann M, Guggenhuber S, Lutz B, Gertsch J, Chaouloff F, Lopez-Rodriguez ML, Grandes P, Rossignol R, Marsicano G. Mitochondrial CB(1) receptors regulate neuronal energy metabolism. Nat Neurosci 15: 558-564, 2012.
-
(2012)
Nat Neurosci
, vol.15
, pp. 558-564
-
-
Benard, G.1
Massa, F.2
Puente, N.3
Lourenco, J.4
Bellocchio, L.5
Soria-Gomez, E.6
Matias, I.7
Delamarre, A.8
Metna-Laurent, M.9
Cannich, A.10
Hebert-Chatelain, E.11
Mulle, C.12
Ortega-Gutierrez, S.13
Martin-Fontecha, M.14
Klugmann, M.15
Guggenhuber, S.16
Lutz, B.17
Gertsch, J.18
Chaouloff, F.19
Lopez-Rodriguez, M.L.20
Grandes, P.21
Rossignol, R.22
Marsicano, G.23
more..
-
9
-
-
0037374766
-
The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells
-
Bensaid M, Gary-Bobo M, Esclangon A, Maffrand JP, Le Fur G, Oury-Donat F, Soubrie P. The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells. Mol Pharmacol 63: 908-914, 2003.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 908-914
-
-
Bensaid, M.1
Gary-Bobo, M.2
Esclangon, A.3
Maffrand, J.P.4
Le Fur, G.5
Oury-Donat, F.6
Soubrie, P.7
-
10
-
-
39049091518
-
Presence of functional cannabinoid receptors in human endocrine pancreas
-
Bermudez-Silva FJ, Suarez J, Baixeras E, Cobo N, Bautista D, Cuesta-Munoz AL, Fuentes E, Juan-Pico P, Castro MJ, Milman G, Mechoulam R, Nadal A, Rodriguez de Fonseca F. Presence of functional cannabinoid receptors in human endocrine pancreas. Diabetologia 51: 476-487, 2008.
-
(2008)
Diabetologia
, vol.51
, pp. 476-487
-
-
Bermudez-Silva, F.J.1
Suarez, J.2
Baixeras, E.3
Cobo, N.4
Bautista, D.5
Cuesta-Munoz, A.L.6
Fuentes, E.7
Juan-Pico, P.8
Castro, M.J.9
Milman, G.10
Mechoulam, R.11
Nadal, A.12
Rodriguez de Fonseca, F.13
-
11
-
-
77957740947
-
Effect of high fat diet enriched with unsaturated and diet rich in saturated fatty acids on sphingolipid metabolism in rat skeletal muscle
-
Blachnio-Zabielska A, Baranowski M, Zabielski P, Gorski J. Effect of high fat diet enriched with unsaturated and diet rich in saturated fatty acids on sphingolipid metabolism in rat skeletal muscle. J Cell Physiol 225: 786-791, 2010.
-
(2010)
J Cell Physiol
, vol.225
, pp. 786-791
-
-
Blachnio-Zabielska, A.1
Baranowski, M.2
Zabielski, P.3
Gorski, J.4
-
12
-
-
33845522074
-
Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity
-
Bluher M, Engeli S, Kloting N, Berndt J, Fasshauer M, Batkai S, Pacher P, Schon MR, Jordan J, Stumvoll M. Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity. Diabetes 55: 3053-3060, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 3053-3060
-
-
Bluher, M.1
Engeli, S.2
Kloting, N.3
Berndt, J.4
Fasshauer, M.5
Batkai, S.6
Pacher, P.7
Schon, M.R.8
Jordan, J.9
Stumvoll, M.10
-
13
-
-
79952451443
-
Obesity, insulin resistance and free fatty acids
-
Boden G. Obesity, insulin resistance and free fatty acids. Curr Opin Endocrinol Diabetes Obes 18: 139-143, 2011.
-
(2011)
Curr Opin Endocrinol Diabetes Obes
, vol.18
, pp. 139-143
-
-
Boden, G.1
-
14
-
-
22144477527
-
Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation
-
Bouaboula M, Hilairet S, Marchand J, Fajas L, Le Fur G, Casellas P. Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation. Eur J Pharmacol 517: 174-181, 2005.
-
(2005)
Eur J Pharmacol
, vol.517
, pp. 174-181
-
-
Bouaboula, M.1
Hilairet, S.2
Marchand, J.3
Fajas, L.4
Le Fur, G.5
Casellas, P.6
-
15
-
-
0029586743
-
Activation of mitogenactivated protein kinases by stimulation of the central cannabinoid receptor CB1
-
Bouaboula M, Poinot-Chazel C, Bourrie B, Canat X, Calandra B, Rinaldi-Carmona M, Le Fur G, Casellas P. Activation of mitogenactivated protein kinases by stimulation of the central cannabinoid receptor CB1. Biochem J 312: 637-641, 1995.
-
(1995)
Biochem J
, vol.312
, pp. 637-641
-
-
Bouaboula, M.1
Poinot-Chazel, C.2
Bourrie, B.3
Canat, X.4
Calandra, B.5
Rinaldi-Carmona, M.6
Le Fur, G.7
Casellas, P.8
-
16
-
-
80051686884
-
Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide
-
Brailoiu GC, Oprea TI, Zhao P, Abood ME, Brailoiu E. Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide. J Biol Chem 286: 29166-29174, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 29166-29174
-
-
Brailoiu, G.C.1
Oprea, T.I.2
Zhao, P.3
Abood, M.E.4
Brailoiu, E.5
-
17
-
-
33644746318
-
Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle
-
Brehm A, Krssak M, Schmid AI, Nowotny P, Waldhausl W, Roden M. Increased lipid availability impairs insulin-stimulated ATP synthesis in human skeletal muscle. Diabetes 55: 136-140, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 136-140
-
-
Brehm, A.1
Krssak, M.2
Schmid, A.I.3
Nowotny, P.4
Waldhausl, W.5
Roden, M.6
-
18
-
-
4544235673
-
Calcium, ATP, and ROS: A mitochondrial love-hate triangle
-
Brookes PS, Yoon Y, Robotham JL, Anders MW, Sheu SS. Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am J Physiol Cell Physiol 287: C817-C833, 2004.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
-
-
Brookes, P.S.1
Yoon, Y.2
Robotham, J.L.3
Anders, M.W.4
Sheu, S.S.5
-
19
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 52: 102-110, 2003.
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
20
-
-
69249213381
-
Anandamide increases swelling and reduces calcium sensitivity of mitochondria
-
Catanzaro G, Rapino C, Oddi S, Maccarrone M. Anandamide increases swelling and reduces calcium sensitivity of mitochondria. Biochem Biophys Res Commun 388: 439-442, 2009.
-
(2009)
Biochem Biophys Res Commun
, vol.388
, pp. 439-442
-
-
Catanzaro, G.1
Rapino, C.2
Oddi, S.3
Maccarrone, M.4
-
21
-
-
0026577311
-
Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism
-
Caulfield MP, Brown DA. Cannabinoid receptor agonists inhibit Ca current in NG108-15 neuroblastoma cells via a pertussis toxin-sensitive mechanism. Br J Pharmacol 106: 231-232, 1992.
-
(1992)
Br J Pharmacol
, vol.106
, pp. 231-232
-
-
Caulfield, M.P.1
Brown, D.A.2
-
22
-
-
33847306530
-
Effects of cannabinoid receptors on skeletal muscle oxidative pathways
-
Cavuoto P, McAinch AJ, Hatzinikolas G, Cameron-Smith D, Wittert GA. Effects of cannabinoid receptors on skeletal muscle oxidative pathways. Mol Cell Endocrinol 267: 63-69, 2007.
-
(2007)
Mol Cell Endocrinol
, vol.267
, pp. 63-69
-
-
Cavuoto, P.1
McAinch, A.J.2
Hatzinikolas, G.3
Cameron-Smith, D.4
Wittert, G.A.5
-
23
-
-
77952493930
-
Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors
-
Cencioni MT, Chiurchiu V, Catanzaro G, Borsellino G, Bernardi G, Battistini L, Maccarrone M. Anandamide suppresses proliferation and cytokine release from primary human T-lymphocytes mainly via CB2 receptors. PLoS One 5: e8688, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Cencioni, M.T.1
Chiurchiu, V.2
Catanzaro, G.3
Borsellino, G.4
Bernardi, G.5
Battistini, L.6
Maccarrone, M.7
-
24
-
-
33746609337
-
Diets high in sugar, fat, and energy induce muscle type-specific adaptations in mitochondrial functions in rats
-
Chanseaume E, Malpuech-Brugere C, Patrac V, Bielicki G, Rousset P, Couturier K, Salles J, Renou JP, Boirie Y, Morio B. Diets high in sugar, fat, and energy induce muscle type-specific adaptations in mitochondrial functions in rats. J Nutr 136: 2194-2200, 2006.
-
(2006)
J Nutr
, vol.136
, pp. 2194-2200
-
-
Chanseaume, E.1
Malpuech-Brugere, C.2
Patrac, V.3
Bielicki, G.4
Rousset, P.5
Couturier, K.6
Salles, J.7
Renou, J.P.8
Boirie, Y.9
Morio, B.10
-
25
-
-
77956342883
-
TNF-alpha induces mitochondrial dysfunction in 3T3-L1 adipocytes
-
Chen XH, Zhao YP, Xue M, Ji CB, Gao CL, Zhu JG, Qin DN, Kou CZ, Qin XH, Tong ML, Guo XR. TNF-alpha induces mitochondrial dysfunction in 3T3-L1 adipocytes. Mol Cell Endocrinol 328: 63-69, 2010.
-
(2010)
Mol Cell Endocrinol
, vol.328
, pp. 63-69
-
-
Chen, X.H.1
Zhao, Y.P.2
Xue, M.3
Ji, C.B.4
Gao, C.L.5
Zhu, J.G.6
Qin, D.N.7
Kou, C.Z.8
Qin, X.H.9
Tong, M.L.10
Guo, X.R.11
-
26
-
-
84894042086
-
Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of longchain ceramides
-
Cinar R, Godlewski G, Liu J, Tam J, Jourdan T, Mukhopadhyay B, Harvey-White J, Kunos G. Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of longchain ceramides. Hepatology 59: 143-153, 2014.
-
(2014)
Hepatology
, vol.59
, pp. 143-153
-
-
Cinar, R.1
Godlewski, G.2
Liu, J.3
Tam, J.4
Jourdan, T.5
Mukhopadhyay, B.6
Harvey-White, J.7
Kunos, G.8
-
27
-
-
0032541111
-
Appetite suppression and weight loss after the cannabinoid antagonist SR 141716
-
Colombo G, Agabio R, Diaz G, Lobina C, Reali R, Gessa GL. Appetite suppression and weight loss after the cannabinoid antagonist SR 141716. Life Sci 63: PL113-PL117, 1998.
-
(1998)
Life Sci
, vol.63
-
-
Colombo, G.1
Agabio, R.2
Diaz, G.3
Lobina, C.4
Reali, R.5
Gessa, G.L.6
-
28
-
-
85047690626
-
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
-
Cota D, Marsicano G, Tschop M, Grubler Y, Flachskamm C, Schubert M, Auer D, Yassouridis A, Thone-Reineke C, Ortmann S, Tomassoni F, Cervino C, Nisoli E, Linthorst AC, Pasquali R, Lutz B, Stalla GK, Pagotto U. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 112: 423-431, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 423-431
-
-
Cota, D.1
Marsicano, G.2
Tschop, M.3
Grubler, Y.4
Flachskamm, C.5
Schubert, M.6
Auer, D.7
Yassouridis, A.8
Thone-Reineke, C.9
Ortmann, S.10
Tomassoni, F.11
Cervino, C.12
Nisoli, E.13
Linthorst, A.C.14
Pasquali, R.15
Lutz, B.16
Stalla, G.K.17
Pagotto, U.18
-
29
-
-
33947606528
-
Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men
-
Cote M, Matias I, Lemieux I, Petrosino S, Almeras N, Despres JP, Di Marzo V. Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men. Int J Obes (Lond) 31: 692-699, 2007.
-
(2007)
Int J Obes (Lond)
, vol.31
, pp. 692-699
-
-
Cote, M.1
Matias, I.2
Lemieux, I.3
Petrosino, S.4
Almeras, N.5
Despres, J.P.6
Di Marzo, V.7
-
30
-
-
61549116530
-
Effect of rimonabant on the high-triglyceride/low-HDL-cholesterol dyslipidemia, intraabdominal adiposity, and liver fat: The ADAGIO-Lipids trial
-
Despres JP, Ross R, Boka G, Almeras N, Lemieux I. Effect of rimonabant on the high-triglyceride/low-HDL-cholesterol dyslipidemia, intraabdominal adiposity, and liver fat: the ADAGIO-Lipids trial. Arterioscler Thromb Vasc Biol 29: 416-423, 2009.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 416-423
-
-
Despres, J.P.1
Ross, R.2
Boka, G.3
Almeras, N.4
Lemieux, I.5
-
31
-
-
84903621738
-
Endocannabinoids decrease neuropathic pain-related behavior in mice through the activation of one or both peripheral CB and CB receptors
-
Desroches J, Charron S, Bouchard JF, Beaulieu P. Endocannabinoids decrease neuropathic pain-related behavior in mice through the activation of one or both peripheral CB and CB receptors. Neuropharmacology, 2013.
-
(2013)
Neuropharmacology
-
-
Desroches, J.1
Charron, S.2
Bouchard, J.F.3
Beaulieu, P.4
-
32
-
-
0024263922
-
Determination and characterization of a cannabinoid receptor in rat brain
-
Devane WA, Dysarz FA 3rd, Johnson MR, Melvin LS, Howlett AC. Determination and characterization of a cannabinoid receptor in rat brain. Mol Pharmacol 34: 605-613, 1988.
-
(1988)
Mol Pharmacol
, vol.34
, pp. 605-613
-
-
Devane, W.A.1
Dysarz III, F.A.2
Johnson, M.R.3
Melvin, L.S.4
Howlett, A.C.5
-
33
-
-
67649159879
-
Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis
-
Deveaux V, Cadoudal T, Ichigotani Y, Teixeira-Clerc F, Louvet A, Manin S, Nhieu JT, Belot MP, Zimmer A, Even P, Cani PD, Knauf C, Burcelin R, Bertola A, Le Marchand-Brustel Y, Gual P, Mallat A, Lotersztajn S. Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis. PLoS One 4: e5844, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Deveaux, V.1
Cadoudal, T.2
Ichigotani, Y.3
Teixeira-Clerc, F.4
Louvet, A.5
Manin, S.6
Nhieu, J.T.7
Belot, M.P.8
Zimmer, A.9
Even, P.10
Cani, P.D.11
Knauf, C.12
Burcelin, R.13
Bertola, A.14
Le Marchand-Brustel, Y.15
Gual, P.16
Mallat, A.17
Lotersztajn, S.18
-
34
-
-
58149471799
-
Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: Associations with changes in metabolic risk factors
-
Di Marzo V, Cote M, Matias I, Lemieux I, Arsenault BJ, Cartier A, Piscitelli F, Petrosino S, Almeras N, Despres JP. Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors. Diabetologia 52: 213-217, 2009.
-
(2009)
Diabetologia
, vol.52
, pp. 213-217
-
-
Di Marzo, V.1
Cote, M.2
Matias, I.3
Lemieux, I.4
Arsenault, B.J.5
Cartier, A.6
Piscitelli, F.7
Petrosino, S.8
Almeras, N.9
Despres, J.P.10
-
35
-
-
32944482013
-
Plant, synthetic, and endogenous cannabinoids in medicine
-
Di Marzo V, Petrocellis LD. Plant, synthetic, and endogenous cannabinoids in medicine. Annu Rev Med 57: 553-574, 2006.
-
(2006)
Annu Rev Med
, vol.57
, pp. 553-574
-
-
Di Marzo, V.1
Petrocellis, L.D.2
-
36
-
-
34548695918
-
The PPARdelta agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells
-
Dimopoulos N, Watson M, Green C, Hundal HS. The PPARdelta agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells. FEBS Lett 581: 4743-4748, 2007.
-
(2007)
FEBS Lett
, vol.581
, pp. 4743-4748
-
-
Dimopoulos, N.1
Watson, M.2
Green, C.3
Hundal, H.S.4
-
37
-
-
61449252830
-
Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle
-
Eckardt K, Sell H, Taube A, Koenen M, Platzbecker B, Cramer A, Horrighs A, Lehtonen M, Tennagels N, Eckel J. Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle. Diabetologia 52: 664-674, 2009.
-
(2009)
Diabetologia
, vol.52
, pp. 664-674
-
-
Eckardt, K.1
Sell, H.2
Taube, A.3
Koenen, M.4
Platzbecker, B.5
Cramer, A.6
Horrighs, A.7
Lehtonen, M.8
Tennagels, N.9
Eckel, J.10
-
38
-
-
25844460609
-
Activation of the peripheral endocannabinoid system in human obesity
-
Engeli S, Bohnke J, Feldpausch M, Gorzelniak K, Janke J, Batkai S, Pacher P, Harvey-White J, Luft FC, Sharma AM, Jordan J. Activation of the peripheral endocannabinoid system in human obesity. Diabetes 54: 2838-2843, 2005.
-
(2005)
Diabetes
, vol.54
, pp. 2838-2843
-
-
Engeli, S.1
Bohnke, J.2
Feldpausch, M.3
Gorzelniak, K.4
Janke, J.5
Batkai, S.6
Pacher, P.7
Harvey-White, J.8
Luft, F.C.9
Sharma, A.M.10
Jordan, J.11
-
39
-
-
0020073412
-
Inhibition of permeability-dependent Ca2+ release from mitochondria by N-acylethanolamines, a class of lipids synthesized in ischemic heart tissue
-
Epps DE, Palmer JW, Schmid HH, Pfeiffer DR. Inhibition of permeability-dependent Ca2+ release from mitochondria by N-acylethanolamines, a class of lipids synthesized in ischemic heart tissue. J Biol Chem 257: 1383-1391, 1982.
-
(1982)
J Biol Chem
, vol.257
, pp. 1383-1391
-
-
Epps, D.E.1
Palmer, J.W.2
Schmid, H.H.3
Pfeiffer, D.R.4
-
40
-
-
0034888225
-
Selective cannabinoid CB1 receptor-mediated inhibition of inducible nitric oxide synthase protein expression in C6 rat glioma cells
-
Esposito G, Izzo AA, Di Rosa M, Iuvone T. Selective cannabinoid CB1 receptor-mediated inhibition of inducible nitric oxide synthase protein expression in C6 rat glioma cells. J Neurochem 78: 835-841, 2001.
-
(2001)
J Neurochem
, vol.78
, pp. 835-841
-
-
Esposito, G.1
Izzo, A.A.2
Di Rosa, M.3
Iuvone, T.4
-
41
-
-
0027185227
-
Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction
-
Felder CC, Briley EM, Axelrod J, Simpson JT, Mackie K, Devane WA. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc Natl Acad Sci USA 90: 7656-7660, 1993.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7656-7660
-
-
Felder, C.C.1
Briley, E.M.2
Axelrod, J.3
Simpson, J.T.4
Mackie, K.5
Devane, W.A.6
-
42
-
-
84860709659
-
FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression
-
Ferber EC, Peck B, Delpuech O, Bell GP, East P, Schulze A. FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression. Cell Death Differ 19: 968-979, 2012.
-
(2012)
Cell Death Differ
, vol.19
, pp. 968-979
-
-
Ferber, E.C.1
Peck, B.2
Delpuech, O.3
Bell, G.P.4
East, P.5
Schulze, A.6
-
43
-
-
84889101230
-
The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation
-
Fonseca BM, Correia-da-Silva G, Teixeira NA. The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation. Apoptosis 18: 1526-1535, 2013.
-
(2013)
Apoptosis
, vol.18
, pp. 1526-1535
-
-
Fonseca, B.M.1
Correia-da-Silva, G.2
Teixeira, N.A.3
-
44
-
-
34547505089
-
Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle
-
Garcia-Roves P, Huss JM, Han DH, Hancock CR, Iglesias-Gutierrez E, Chen M, Holloszy JO. Raising plasma fatty acid concentration induces increased biogenesis of mitochondria in skeletal muscle. Proc Natl Acad Sci USA 104: 10709-10713, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 10709-10713
-
-
Garcia-Roves, P.1
Huss, J.M.2
Han, D.H.3
Hancock, C.R.4
Iglesias-Gutierrez, E.5
Chen, M.6
Holloszy, J.O.7
-
45
-
-
58149099037
-
Gain-offunction R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal muscle
-
Garcia-Roves PM, Osler ME, Holmstrom MH, Zierath JR. Gain-offunction R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal muscle. J Biol Chem 283: 35724-35734, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 35724-35734
-
-
Garcia-Roves, P.M.1
Osler, M.E.2
Holmstrom, M.H.3
Zierath, J.R.4
-
46
-
-
84859560882
-
Role of mitochondrial Ca2+ in the regulation of cellular energetics
-
Glancy B, Balaban RS. Role of mitochondrial Ca2+ in the regulation of cellular energetics. Biochemistry 51: 2959-2973, 2012.
-
(2012)
Biochemistry
, vol.51
, pp. 2959-2973
-
-
Glancy, B.1
Balaban, R.S.2
-
47
-
-
33751198532
-
Cannabinoid receptor-mediated apoptosis induced by R(+)-methanandamide and Win55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell lymphoma
-
Gustafsson K, Christensson B, Sander B, Flygare J. Cannabinoid receptor-mediated apoptosis induced by R(+)-methanandamide and Win55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell lymphoma. Mol Pharmacol 70: 1612-1620, 2006.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1612-1620
-
-
Gustafsson, K.1
Christensson, B.2
Sander, B.3
Flygare, J.4
-
48
-
-
84872332700
-
Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA)
-
Hagland HR, Nilsson LI, Burri L, Nikolaisen J, Berge RK, Tronstad KJ. Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA). Biochem Biophys Res Commun 430: 573-578, 2013.
-
(2013)
Biochem Biophys Res Commun
, vol.430
, pp. 573-578
-
-
Hagland, H.R.1
Nilsson, L.I.2
Burri, L.3
Nikolaisen, J.4
Berge, R.K.5
Tronstad, K.J.6
-
49
-
-
0035133331
-
Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
-
Hajduch E, Balendran A, Batty IH, Litherland GJ, Blair AS, Downes CP, Hundal HS. Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. Diabetologia 44: 173-183, 2001.
-
(2001)
Diabetologia
, vol.44
, pp. 173-183
-
-
Hajduch, E.1
Balendran, A.2
Batty, I.H.3
Litherland, G.J.4
Blair, A.S.5
Downes, C.P.6
Hundal, H.S.7
-
50
-
-
40449097575
-
Targeting of PKCzeta and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide
-
Hajduch E, Turban S, Le Liepvre X, Le Lay S, Lipina C, Dimopoulos N, Dugail I, Hundal HS. Targeting of PKCzeta and PKB to caveolin-enriched microdomains represents a crucial step underpinning the disruption in PKB-directed signalling by ceramide. Biochem J 410: 369-379, 2008.
-
(2008)
Biochem J
, vol.410
, pp. 369-379
-
-
Hajduch, E.1
Turban, S.2
Le Liepvre, X.3
Le Lay, S.4
Lipina, C.5
Dimopoulos, N.6
Dugail, I.7
Hundal, H.S.8
-
51
-
-
0037423717
-
Reduced expression of PGC-1 and insulin-signaling molecules in adipose tissue is associated with insulin resistance
-
Hammarstedt A, Jansson PA, Wesslau C, Yang X, Smith U. Reduced expression of PGC-1 and insulin-signaling molecules in adipose tissue is associated with insulin resistance. Biochem Biophys Res Commun 301: 578-582, 2003.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 578-582
-
-
Hammarstedt, A.1
Jansson, P.A.2
Wesslau, C.3
Yang, X.4
Smith, U.5
-
52
-
-
45549089279
-
High-fat diets cause insulin resistance despite an increase in muscle mitochondria
-
Hancock CR, Han DH, Chen M, Terada S, Yasuda T, Wright DC, Holloszy JO. High-fat diets cause insulin resistance despite an increase in muscle mitochondria. Proc Natl Acad Sci USA 105: 7815-7820, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7815-7820
-
-
Hancock, C.R.1
Han, D.H.2
Chen, M.3
Terada, S.4
Yasuda, T.5
Wright, D.C.6
Holloszy, J.O.7
-
53
-
-
34147175161
-
Markers of mitochondrial biogenesis and metabolism are lower in overweight and obese insulin-resistant subjects
-
Heilbronn LK, Gan SK, Turner N, Campbell LV, Chisholm DJ. Markers of mitochondrial biogenesis and metabolism are lower in overweight and obese insulin-resistant subjects. J Clin Endocrinol Metab 92: 1467-1473, 2007.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 1467-1473
-
-
Heilbronn, L.K.1
Gan, S.K.2
Turner, N.3
Campbell, L.V.4
Chisholm, D.J.5
-
54
-
-
33744913027
-
The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway
-
Herrera B, Carracedo A, Diez-Zaera M, Gomez del Pulgar T, Guzman M, Velasco G. The CB2 cannabinoid receptor signals apoptosis via ceramide-dependent activation of the mitochondrial intrinsic pathway. Exp Cell Res 312: 2121-2131, 2006.
-
(2006)
Exp Cell Res
, vol.312
, pp. 2121-2131
-
-
Herrera, B.1
Carracedo, A.2
Diez-Zaera, M.3
del Gomez Pulgar, T.4
Guzman, M.5
Velasco, G.6
-
55
-
-
0033647159
-
Cellular signal transduction by anandamide and 2-arachidonoylglycerol
-
Howlett AC, Mukhopadhyay S. Cellular signal transduction by anandamide and 2-arachidonoylglycerol. Chem Phys Lipids 108: 53-70, 2000.
-
(2000)
Chem Phys Lipids
, vol.108
, pp. 53-70
-
-
Howlett, A.C.1
Mukhopadhyay, S.2
-
56
-
-
77956800047
-
G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population
-
Hu WC, Feng P. G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population. Arch Med Res 41: 378-382, 2010.
-
(2010)
Arch Med Res
, vol.41
, pp. 378-382
-
-
Hu, W.C.1
Feng, P.2
-
57
-
-
33744552611
-
Effect of capsazepine on cytosolic Ca(2+) levels and proliferation of human prostate cancer cells
-
Huang JK, Cheng HH, Huang CJ, Kuo CC, Chen WC, Liu SI, Hsu SS, Chang HT, Lu YC, Tseng LL, Chiang AJ, Chou CT, Jan CR. Effect of capsazepine on cytosolic Ca(2+) levels and proliferation of human prostate cancer cells. Toxicol In Vitro 20: 567-574, 2006.
-
(2006)
Toxicol In Vitro
, vol.20
, pp. 567-574
-
-
Huang, J.K.1
Cheng, H.H.2
Huang, C.J.3
Kuo, C.C.4
Chen, W.C.5
Liu, S.I.6
Hsu, S.S.7
Chang, H.T.8
Lu, Y.C.9
Tseng, L.L.10
Chiang, A.J.11
Chou, C.T.12
Jan, C.R.13
-
58
-
-
78149379077
-
Rimonabant inhibits TNF-alpha-induced endothelial IL-6 secretion via CB1 receptor and cAMP-dependent protein kinase pathway
-
Huang NL, Juang JM, Wang YH, Hsueh CH, Liang YJ, Lin JL, Tsai CT, Lai LP. Rimonabant inhibits TNF-alpha-induced endothelial IL-6 secretion via CB1 receptor and cAMP-dependent protein kinase pathway. Acta Pharmacol Sin 31: 1447-1453, 2010.
-
(2010)
Acta Pharmacol Sin
, vol.31
, pp. 1447-1453
-
-
Huang, N.L.1
Juang, J.M.2
Wang, Y.H.3
Hsueh, C.H.4
Liang, Y.J.5
Lin, J.L.6
Tsai, C.T.7
Lai, L.P.8
-
59
-
-
33745325873
-
Impact of mitochondrial reactive oxygen species and apoptosis signal-regulating kinase 1 on insulin signaling
-
Imoto K, Kukidome D, Nishikawa T, Matsuhisa T, Sonoda K, Fujisawa K, Yano M, Motoshima H, Taguchi T, Tsuruzoe K, Matsumura T, Ichijo H, Araki E. Impact of mitochondrial reactive oxygen species and apoptosis signal-regulating kinase 1 on insulin signaling. Diabetes 55: 1197-1204, 2006.
-
(2006)
Diabetes
, vol.55
, pp. 1197-1204
-
-
Imoto, K.1
Kukidome, D.2
Nishikawa, T.3
Matsuhisa, T.4
Sonoda, K.5
Fujisawa, K.6
Yano, M.7
Motoshima, H.8
Taguchi, T.9
Tsuruzoe, K.10
Matsumura, T.11
Ichijo, H.12
Araki, E.13
-
60
-
-
77951872309
-
Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/ SIRT1
-
Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T. Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/ SIRT1. Nature 464: 1313-1319, 2010.
-
(2010)
Nature
, vol.464
, pp. 1313-1319
-
-
Iwabu, M.1
Yamauchi, T.2
Okada-Iwabu, M.3
Sato, K.4
Nakagawa, T.5
Funata, M.6
Yamaguchi, M.7
Namiki, S.8
Nakayama, R.9
Tabata, M.10
Ogata, H.11
Kubota, N.12
Takamoto, I.13
Hayashi, Y.K.14
Yamauchi, N.15
Waki, H.16
Fukayama, M.17
Nishino, I.18
Tokuyama, K.19
Ueki, K.20
Oike, Y.21
Ishii, S.22
Hirose, K.23
Shimizu, T.24
Touhara, K.25
Kadowaki, T.26
more..
-
61
-
-
24644500204
-
The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance
-
Jbilo O, Ravinet-Trillou C, Arnone M, Buisson I, Bribes E, Peleraux A, Penarier G, Soubrie P, Le Fur G, Galiegue S, Casellas P. The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through the regulation of lipolysis and energy balance. FASEB J 19: 1567-1569, 2005.
-
(2005)
FASEB J
, vol.19
, pp. 1567-1569
-
-
Jbilo, O.1
Ravinet-Trillou, C.2
Arnone, M.3
Buisson, I.4
Bribes, E.5
Peleraux, A.6
Penarier, G.7
Soubrie, P.8
Le Fur, G.9
Galiegue, S.10
Casellas, P.11
-
62
-
-
3342979420
-
Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice
-
Jin K, Xie L, Kim SH, Parmentier-Batteur S, Sun Y, Mao XO, Childs J, Greenberg DA. Defective adult neurogenesis in CB1 cannabinoid receptor knockout mice. Mol Pharmacol 66: 204-208, 2004.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 204-208
-
-
Jin, K.1
Xie, L.2
Kim, S.H.3
Parmentier-Batteur, S.4
Sun, Y.5
Mao, X.O.6
Childs, J.7
Greenberg, D.A.8
-
63
-
-
33846012164
-
Role of AMPKα2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle
-
Jorgensen SB, Treebak JT, Viollet B, Schjerling P, Vaulont S, Wojtaszewski JF, Richter EA. Role of AMPKα2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle. Am J Physiol Endocrinol Metab 292: E331-E339, 2007.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
-
-
Jorgensen, S.B.1
Treebak, J.T.2
Viollet, B.3
Schjerling, P.4
Vaulont, S.5
Wojtaszewski, J.F.6
Richter, E.A.7
-
64
-
-
84857445031
-
Antagonism of peripheral hepatic cannabinoid receptor-1 improves liver lipid metabolism in mice: Evidence from cultured explants
-
Jourdan T, Demizieux L, Gresti J, Djaouti L, Gaba L, Verges B, Degrace P. Antagonism of peripheral hepatic cannabinoid receptor-1 improves liver lipid metabolism in mice: evidence from cultured explants. Hepatology 55: 790-799, 2012.
-
(2012)
Hepatology
, vol.55
, pp. 790-799
-
-
Jourdan, T.1
Demizieux, L.2
Gresti, J.3
Djaouti, L.4
Gaba, L.5
Verges, B.6
Degrace, P.7
-
65
-
-
77951184370
-
CB1 antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice
-
Jourdan T, Djaouti L, Demizieux L, Gresti J, Verges B, Degrace P. CB1 antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice. Diabetes 59: 926-934, 2010.
-
(2010)
Diabetes
, vol.59
, pp. 926-934
-
-
Jourdan, T.1
Djaouti, L.2
Demizieux, L.3
Gresti, J.4
Verges, B.5
Degrace, P.6
-
66
-
-
29544435299
-
Cannabinoid receptors regulate Ca(2+) signals and insulin secretion in pancreatic beta-cell
-
Juan-Pico P, Fuentes E, Bermudez-Silva FJ, Javier Diaz-Molina F, Ripoll C, Rodriguez de Fonseca F, Nadal A. Cannabinoid receptors regulate Ca(2+) signals and insulin secretion in pancreatic beta-cell. Cell Calcium 39: 155-162, 2006.
-
(2006)
Cell Calcium
, vol.39
, pp. 155-162
-
-
Juan-Pico, P.1
Fuentes, E.2
Bermudez-Silva, F.J.3
Javier Diaz-Molina, F.4
Ripoll, C.5
Rodriguez de Fonseca, F.6
Nadal, A.7
-
67
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
-
Kelley DE, He J, Menshikova EV, Ritov VB. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51: 2944-2950, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.E.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
68
-
-
0027946529
-
Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus
-
Kelley DE, Simoneau JA. Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus. J Clin Invest 94: 2349-2356, 1994.
-
(1994)
J Clin Invest
, vol.94
, pp. 2349-2356
-
-
Kelley, D.E.1
Simoneau, J.A.2
-
69
-
-
0035984946
-
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: Stimulation of eating by 2-arachidonoyl glycerol
-
Kirkham TC, Williams CM, Fezza F, Di Marzo V. Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol. Br J Pharmacol 136: 550-557, 2002.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 550-557
-
-
Kirkham, T.C.1
Williams, C.M.2
Fezza, F.3
Di Marzo, V.4
-
70
-
-
0022256871
-
Flux of palmitate through the peroxisomal and mitochondrial beta-oxidation systems in isolated rat hepatocytes
-
Kondrup J, Lazarow PB. Flux of palmitate through the peroxisomal and mitochondrial beta-oxidation systems in isolated rat hepatocytes. Biochim Biophys Acta 835: 147-153, 1985.
-
(1985)
Biochim Biophys Acta
, vol.835
, pp. 147-153
-
-
Kondrup, J.1
Lazarow, P.B.2
-
71
-
-
84867871977
-
Differential nitric oxide levels in the blood and skeletal muscle of type 2 diabetic subjects may be consequence of adiposity: A preliminary study
-
Krause M, Rodrigues-Krause J, O'Hagan C, De Vito G, Boreham C, Susta D, Newsholme P, Murphy C. Differential nitric oxide levels in the blood and skeletal muscle of type 2 diabetic subjects may be consequence of adiposity: a preliminary study. Metabolism 61: 1528-1537, 2012.
-
(2012)
Metabolism
, vol.61
, pp. 1528-1537
-
-
Krause, M.1
Rodrigues-Krause, J.2
O'Hagan, C.3
De Vito, G.4
Boreham, C.5
Susta, D.6
Newsholme, P.7
Murphy, C.8
-
72
-
-
0030853692
-
SR141716A is an inverse agonist at the human cannabinoid CB1 receptor
-
Landsman RS, Burkey TH, Consroe P, Roeske WR, Yamamura HI. SR141716A is an inverse agonist at the human cannabinoid CB1 receptor. Eur J Pharmacol 334: R1-R2, 1997.
-
(1997)
Eur J Pharmacol
, vol.334
-
-
Landsman, R.S.1
Burkey, T.H.2
Consroe, P.3
Roeske, W.R.4
Yamamura, H.I.5
-
73
-
-
78049341843
-
Cannabinoid receptors are coupled to stimulation of insulin secretion from mouse MIN6 beta-cells
-
Li C, Jones PM, Persaud SJ. Cannabinoid receptors are coupled to stimulation of insulin secretion from mouse MIN6 beta-cells. Cell Physiol Biochem 26: 187-196, 2010.
-
(2010)
Cell Physiol Biochem
, vol.26
, pp. 187-196
-
-
Li, C.1
Jones, P.M.2
Persaud, S.J.3
-
74
-
-
84877154617
-
Anandamide reduces intracellular Ca2+ concentration through suppression of Na+/Ca2+ exchanger current in rat cardiac myocytes
-
Li Q, Cui N, Du Y, Ma H, Zhang Y. Anandamide reduces intracellular Ca2+ concentration through suppression of Na+/Ca2+ exchanger current in rat cardiac myocytes. PLoS One 8: e63386, 2013.
-
(2013)
PLoS One
, vol.8
-
-
Li, Q.1
Cui, N.2
Du, Y.3
Ma, H.4
Zhang, Y.5
-
75
-
-
84878400659
-
Activation of cannabinoid type 2 receptor by JWH133 protects heart against ischemia/ reperfusion-induced apoptosis
-
Li Q, Wang F, Zhang YM, Zhou JJ, Zhang Y. Activation of cannabinoid type 2 receptor by JWH133 protects heart against ischemia/ reperfusion-induced apoptosis. Cell Physiol Biochem 31: 693-702, 2013.
-
(2013)
Cell Physiol Biochem
, vol.31
, pp. 693-702
-
-
Li, Q.1
Wang, F.2
Zhang, Y.M.3
Zhou, J.J.4
Zhang, Y.5
-
76
-
-
79952101635
-
Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: An effect attenuated by phycocyanin
-
Li XL, Chen T, Wong YS, Xu G, Fan RR, Zhao HL, Chan JC. Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: An effect attenuated by phycocyanin. Int J Biochem Cell Biol 43: 525-534, 2011.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 525-534
-
-
Li, X.L.1
Chen, T.2
Wong, Y.S.3
Xu, G.4
Fan, R.R.5
Zhao, H.L.6
Chan, J.C.7
-
77
-
-
84891534986
-
Mitochondrial substrate availability and its role in lipid-induced insulin resistance and proinflammatory signaling in skeletal muscle
-
Lipina C, Macrae K, Suhm T, Weigert C, Blachnio-Zabielska A, Baranowski M, Gorski J, Burgess K, Hundal HS. Mitochondrial substrate availability and its role in lipid-induced insulin resistance and proinflammatory signaling in skeletal muscle. Diabetes 62: 3426-3436, 2013.
-
(2013)
Diabetes
, vol.62
, pp. 3426-3436
-
-
Lipina, C.1
Macrae, K.2
Suhm, T.3
Weigert, C.4
Blachnio-Zabielska, A.5
Baranowski, M.6
Gorski, J.7
Burgess, K.8
Hundal, H.S.9
-
78
-
-
77449118145
-
Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells
-
Lipina C, Stretton C, Hastings S, Hundal JS, Mackie K, Irving AJ, Hundal HS. Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells. Diabetes 59: 375-385, 2010.
-
(2010)
Diabetes
, vol.59
, pp. 375-385
-
-
Lipina, C.1
Stretton, C.2
Hastings, S.3
Hundal, J.S.4
Mackie, K.5
Irving, A.J.6
Hundal, H.S.7
-
79
-
-
84857784321
-
TRPV1 activation improves exercise endurance and energy metabolism through PGC-1alpha upregulation in mice
-
Luo Z, Ma L, Zhao Z, He H, Yang D, Feng X, Ma S, Chen X, Zhu T, Cao T, Liu D, Nilius B, Huang Y, Yan Z, Zhu Z. TRPV1 activation improves exercise endurance and energy metabolism through PGC-1alpha upregulation in mice. Cell Res 22: 551-564, 2012.
-
(2012)
Cell Res
, vol.22
, pp. 551-564
-
-
Luo, Z.1
Ma, L.2
Zhao, Z.3
He, H.4
Yang, D.5
Feng, X.6
Ma, S.7
Chen, X.8
Zhu, T.9
Cao, T.10
Liu, D.11
Nilius, B.12
Huang, Y.13
Yan, Z.14
Zhu, Z.15
-
80
-
-
84860672626
-
Protein kinase A subunit alpha catalytic and a kinase anchoring protein 79 in human placental mitochondria
-
Ma MP, Thomson M. Protein kinase A subunit alpha catalytic and a kinase anchoring protein 79 in human placental mitochondria. Open Biochem J 6: 23-30, 2012.
-
(2012)
Open Biochem J
, vol.6
, pp. 23-30
-
-
Ma, M.P.1
Thomson, M.2
-
81
-
-
84864397721
-
Diabetes reduces beta-cell mitochondria and induces distinct morphological abnormalities, which are reproducible by high glucose in vitro with attendant dysfunction
-
Ma Z, Wirstrom T, Borg LA, Larsson-Nyren G, Hals I, Bondo-Hansen J, Grill V, Bjorklund A. Diabetes reduces beta-cell mitochondria and induces distinct morphological abnormalities, which are reproducible by high glucose in vitro with attendant dysfunction. Islets 4: 233-242, 2012.
-
(2012)
Islets
, vol.4
, pp. 233-242
-
-
Ma, Z.1
Wirstrom, T.2
Borg, L.A.3
Larsson-Nyren, G.4
Hals, I.5
Bondo-Hansen, J.6
Grill, V.7
Bjorklund, A.8
-
82
-
-
42349116262
-
Cannabinoid receptors: Where they are and what they do
-
Mackie K. Cannabinoid receptors: where they are and what they do. J Neuroendocrinol 20, Suppl 1: 10-14, 2008.
-
(2008)
J Neuroendocrinol
, vol.20
, Issue.SUPPL. 1
, pp. 10-14
-
-
Mackie, K.1
-
83
-
-
0026603679
-
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells
-
Mackie K, Hille B. Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc Natl Acad Sci USA 89: 3825-3829, 1992.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 3825-3829
-
-
Mackie, K.1
Hille, B.2
-
84
-
-
62749164774
-
Protein kinase A regulatory subunits in human adipose tissue: Decreased R2B expression and activity in adipocytes from obese subjects
-
Mantovani G, Bondioni S, Alberti L, Gilardini L, Invitti C, Corbetta S, Zappa MA, Ferrero S, Lania AG, Bosari S, Beck-Peccoz P, Spada A. Protein kinase A regulatory subunits in human adipose tissue: decreased R2B expression and activity in adipocytes from obese subjects. Diabetes 58: 620-626, 2009.
-
(2009)
Diabetes
, vol.58
, pp. 620-626
-
-
Mantovani, G.1
Bondioni, S.2
Alberti, L.3
Gilardini, L.4
Invitti, C.5
Corbetta, S.6
Zappa, M.A.7
Ferrero, S.8
Lania, A.G.9
Bosari, S.10
Beck-Peccoz, P.11
Spada, A.12
-
85
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346: 561-564, 1990.
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
86
-
-
84859046557
-
Delta(9)-tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells
-
McHugh D, Page J, Dunn E, Bradshaw HB. Delta(9)-tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. Br J Pharmacol 165: 2414-2424, 2012.
-
(2012)
Br J Pharmacol
, vol.165
, pp. 2414-2424
-
-
McHugh, D.1
Page, J.2
Dunn, E.3
Bradshaw, H.B.4
-
87
-
-
0029012014
-
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
-
Mechoulam R, Ben-Shabat S, Hanus L, Ligumsky M, Kaminski NE, Schatz AR, Gopher A, Almog S, Martin BR, Compton DR, Pertwee RG, Griffin G, Bayewitch M, Barg J, Vogel Z. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem Pharmacol 50: 83-90, 1995.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 83-90
-
-
Mechoulam, R.1
Ben-Shabat, S.2
Hanus, L.3
Ligumsky, M.4
Kaminski, N.E.5
Schatz, A.R.6
Gopher, A.7
Almog, S.8
Martin, B.R.9
Compton, D.R.10
Pertwee, R.G.11
Griffin, G.12
Bayewitch, M.13
Barg, J.14
Vogel, Z.15
-
88
-
-
0033405883
-
Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells
-
Melck D, Rueda D, Galve-Roperh I, De Petrocellis L, Guzman M, Di Marzo V. Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells. FEBS Lett 463: 235-240, 1999.
-
(1999)
FEBS Lett
, vol.463
, pp. 235-240
-
-
Melck, D.1
Rueda, D.2
Galve-Roperh, I.3
De Petrocellis, L.4
Guzman, M.5
Di Marzo, V.6
-
90
-
-
84861200393
-
Anandamide induces matrix metalloproteinase-2 production through cannabinoid-1 receptor and transient receptor potential vanilloid-1 in human dental pulp cells in culture
-
Miyashita K, Oyama T, Sakuta T, Tokuda M, Torii M. Anandamide induces matrix metalloproteinase-2 production through cannabinoid-1 receptor and transient receptor potential vanilloid-1 in human dental pulp cells in culture. J Endod 38: 786-790, 2012.
-
(2012)
J Endod
, vol.38
, pp. 786-790
-
-
Miyashita, K.1
Oyama, T.2
Sakuta, T.3
Tokuda, M.4
Torii, M.5
-
91
-
-
84861389481
-
Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart
-
Mulligan CM, Sparagna GC, Le CH, De Mooy AB, Routh MA, Holmes MG, Hickson-Bick DL, Zarini S, Murphy RC, Xu FY, Hatch GM, McCune SA, Moore RL, Chicco AJ. Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart. Cardiovasc Res 94: 460-468, 2012.
-
(2012)
Cardiovasc Res
, vol.94
, pp. 460-468
-
-
Mulligan, C.M.1
Sparagna, G.C.2
Le, C.H.3
De Mooy, A.B.4
Routh, M.A.5
Holmes, M.G.6
Hickson-Bick, D.L.7
Zarini, S.8
Murphy, R.C.9
Xu, F.Y.10
Hatch, G.M.11
McCune, S.A.12
Moore, R.L.13
Chicco, A.J.14
-
92
-
-
0036224157
-
Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells
-
Muoio DM, Way JM, Tanner CJ, Winegar DA, Kliewer SA, Houmard JA, Kraus WE, Dohm GL. Peroxisome proliferator-activated receptor-alpha regulates fatty acid utilization in primary human skeletal muscle cells. Diabetes 51: 901-909, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 901-909
-
-
Muoio, D.M.1
Way, J.M.2
Tanner, C.J.3
Winegar, D.A.4
Kliewer, S.A.5
Houmard, J.A.6
Kraus, W.E.7
Dohm, G.L.8
-
93
-
-
37349059404
-
Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet beta-cells via CB1 receptors
-
Nakata M, Yada T. Cannabinoids inhibit insulin secretion and cytosolic Ca2+ oscillation in islet beta-cells via CB1 receptors. Regul Pept 145: 49-53, 2008.
-
(2008)
Regul Pept
, vol.145
, pp. 49-53
-
-
Nakata, M.1
Yada, T.2
-
94
-
-
0026519290
-
Metabolic response to a high-fat diet in neonatal and adult rat muscle
-
Nemeth PM, Rosser BW, Choksi RM, Norris BJ, Baker KM. Metabolic response to a high-fat diet in neonatal and adult rat muscle. Am J Physiol Cell Physiol 262: C282-C286, 1992.
-
(1992)
Am J Physiol Cell Physiol
, vol.262
-
-
Nemeth, P.M.1
Rosser, B.W.2
Choksi, R.M.3
Norris, B.J.4
Baker, K.M.5
-
95
-
-
34547652578
-
Impact of mitochondrial ROS production in the pathogenesis of insulin resistance
-
Nishikawa T, Kukidome D, Sonoda K, Fujisawa K, Matsuhisa T, Motoshima H, Matsumura T, Araki E. Impact of mitochondrial ROS production in the pathogenesis of insulin resistance. Diabetes Res Clin Pract 77, Suppl 1: S161-S164, 2007.
-
(2007)
Diabetes Res Clin Pract
, vol.77
, Issue.SUPPL. 1
-
-
Nishikawa, T.1
Kukidome, D.2
Sonoda, K.3
Fujisawa, K.4
Matsuhisa, T.5
Motoshima, H.6
Matsumura, T.7
Araki, E.8
-
96
-
-
79952911854
-
Endocannabinoids and obesity development-the adipose tissue
-
Nisoli E. Endocannabinoids and obesity development-the adipose tissue. Drug Disc Today Dis Mech 7: e199-e204, 2010.
-
(2010)
Drug Disc Today Dis Mech
, vol.7
-
-
Nisoli, E.1
-
97
-
-
0347579845
-
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
-
Nisoli E, Clementi E, Paolucci C, Cozzi V, Tonello C, Sciorati C, Bracale R, Valerio A, Francolini M, Moncada S, Carruba MO. Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science 299: 896-899, 2003.
-
(2003)
Science
, vol.299
, pp. 896-899
-
-
Nisoli, E.1
Clementi, E.2
Paolucci, C.3
Cozzi, V.4
Tonello, C.5
Sciorati, C.6
Bracale, R.7
Valerio, A.8
Francolini, M.9
Moncada, S.10
Carruba, M.O.11
-
98
-
-
9344220484
-
Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals
-
Nisoli E, Falcone S, Tonello C, Cozzi V, Palomba L, Fiorani M, Pisconti A, Brunelli S, Cardile A, Francolini M, Cantoni O, Carruba MO, Moncada S, Clementi E. Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals. Proc Natl Acad Sci USA 101: 16507-16512, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16507-16512
-
-
Nisoli, E.1
Falcone, S.2
Tonello, C.3
Cozzi, V.4
Palomba, L.5
Fiorani, M.6
Pisconti, A.7
Brunelli, S.8
Cardile, A.9
Francolini, M.10
Cantoni, O.11
Carruba, M.O.12
Moncada, S.13
Clementi, E.14
-
99
-
-
85047693638
-
Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones
-
Norris AW, Chen L, Fisher SJ, Szanto I, Ristow M, Jozsi AC, Hirshman MF, Rosen ED, Goodyear LJ, Gonzalez FJ, Spiegelman BM, Kahn CR. Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones. J Clin Invest 112: 608-618, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 608-618
-
-
Norris, A.W.1
Chen, L.2
Fisher, S.J.3
Szanto, I.4
Ristow, M.5
Jozsi, A.C.6
Hirshman, M.F.7
Rosen, E.D.8
Goodyear, L.J.9
Gonzalez, F.J.10
Spiegelman, B.M.11
Kahn, C.R.12
-
100
-
-
79953206959
-
Central endocannabinoid signaling regulates hepatic glucose production and systemic lipolysis
-
O'Hare JD, Zielinski E, Cheng B, Scherer T, Buettner C. Central endocannabinoid signaling regulates hepatic glucose production and systemic lipolysis. Diabetes 60: 1055-1062, 2011.
-
(2011)
Diabetes
, vol.60
, pp. 1055-1062
-
-
O'Hare, J.D.1
Zielinski, E.2
Cheng, B.3
Scherer, T.4
Buettner, C.5
-
101
-
-
77954175115
-
Cannabinoid activation of peroxisome proliferator-activated receptors: Potential for modulation of inflammatory disease
-
O'Sullivan SE, Kendall DA. Cannabinoid activation of peroxisome proliferator-activated receptors: potential for modulation of inflammatory disease. Immunobiology 215: 611-616, 2010.
-
(2010)
Immunobiology
, vol.215
, pp. 611-616
-
-
O'Sullivan, S.E.1
Kendall, D.A.2
-
102
-
-
20944436157
-
Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
-
Osei-Hyiaman D, DePetrillo M, Pacher P, Liu J, Radaeva S, Batkai S, Harvey-White J, Mackie K, Offertaler L, Wang L, Kunos G. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest 115: 1298-1305, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 1298-1305
-
-
Osei-Hyiaman, D.1
DePetrillo, M.2
Pacher, P.3
Liu, J.4
Radaeva, S.5
Batkai, S.6
Harvey-White, J.7
Mackie, K.8
Offertaler, L.9
Wang, L.10
Kunos, G.11
-
103
-
-
51349153318
-
Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice
-
Osei-Hyiaman D, Liu J, Zhou L, Godlewski G, Harvey-White J, Jeong WI, Batkai S, Marsicano G, Lutz B, Buettner C, Kunos G. Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest 118: 3160-3169, 2008.
-
(2008)
J Clin Invest
, vol.118
, pp. 3160-3169
-
-
Osei-Hyiaman, D.1
Liu, J.2
Zhou, L.3
Godlewski, G.4
Harvey-White, J.5
Jeong, W.I.6
Batkai, S.7
Marsicano, G.8
Lutz, B.9
Buettner, C.10
Kunos, G.11
-
104
-
-
33645519808
-
How many sites of action for endocannabinoids to control energy metabolism?
-
Pagotto U, Cervino C, Vicennati V, Marsicano G, Lutz B, Pasquali R. How many sites of action for endocannabinoids to control energy metabolism? Int J Obes (Lond) 30, Suppl 1: S39-S43, 2006.
-
(2006)
Int J Obes (Lond)
, vol.30
, Issue.SUPPL. 1
-
-
Pagotto, U.1
Cervino, C.2
Vicennati, V.3
Marsicano, G.4
Lutz, B.5
Pasquali, R.6
-
105
-
-
0029872234
-
Rat brain cannabinoid receptor modulates N-type Ca2+ channels in a neuronal expression system
-
Pan X, Ikeda SR, Lewis DL. Rat brain cannabinoid receptor modulates N-type Ca2+ channels in a neuronal expression system. Mol Pharmacol 49: 707-714, 1996.
-
(1996)
Mol Pharmacol
, vol.49
, pp. 707-714
-
-
Pan, X.1
Ikeda, S.R.2
Lewis, D.L.3
-
106
-
-
80053276336
-
The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice
-
Pang Z, Wu NN, Zhao W, Chain DC, Schaffer E, Zhang X, Yamdagni P, Palejwala VA, Fan C, Favara SG, Dressler HM, Economides KD, Weinstock D, Cavallo JS, Naimi S, Galzin AM, Guillot E, Pruniaux MP, Tocci MJ, Polites HG. The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice. Obesity (Silver Spring) 19: 1923-1934, 2011.
-
(2011)
Obesity (Silver Spring)
, vol.19
, pp. 1923-1934
-
-
Pang, Z.1
Wu, N.N.2
Zhao, W.3
Chain, D.C.4
Schaffer, E.5
Zhang, X.6
Yamdagni, P.7
Palejwala, V.A.8
Fan, C.9
Favara, S.G.10
Dressler, H.M.11
Economides, K.D.12
Weinstock, D.13
Cavallo, J.S.14
Naimi, S.15
Galzin, A.M.16
Guillot, E.17
Pruniaux, M.P.18
Tocci, M.J.19
Polites, H.G.20
more..
-
107
-
-
35348858145
-
The G1422A variant of the cannabinoid receptor gene (CNR1) is associated with abdominal adiposity in obese men
-
Peeters A, Beckers S, Mertens I, Van Hul W, Van Gaal L. The G1422A variant of the cannabinoid receptor gene (CNR1) is associated with abdominal adiposity in obese men. Endocrine 31: 138-141, 2007.
-
(2007)
Endocrine
, vol.31
, pp. 138-141
-
-
Peeters, A.1
Beckers, S.2
Mertens, I.3
Van Hul, W.4
Van Gaal, L.5
-
108
-
-
32644441249
-
Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: A randomized controlled trial
-
Pi-Sunyer FX, Aronne LJ, Heshmati HM, Devin J, Rosenstock J. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial. JAMA 295: 761-775, 2006.
-
(2006)
JAMA
, vol.295
, pp. 761-775
-
-
Pi-Sunyer, F.X.1
Aronne, L.J.2
Heshmati, H.M.3
Devin, J.4
Rosenstock, J.5
-
109
-
-
0033913223
-
Dynamics of insulin secretion in obesity and diabetes
-
Polonsky KS. Dynamics of insulin secretion in obesity and diabetes. Int J Obes Relat Metab Disord 24, Suppl 2: S29-S31, 2000.
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, Issue.SUPPL. 2
-
-
Polonsky, K.S.1
-
110
-
-
33644867986
-
Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury
-
Prabu SK, Anandatheerthavarada HK, Raza H, Srinivasan S, Spear JF, Avadhani NG. Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury. J Biol Chem 281: 2061-2070, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 2061-2070
-
-
Prabu, S.K.1
Anandatheerthavarada, H.K.2
Raza, H.3
Srinivasan, S.4
Spear, J.F.5
Avadhani, N.G.6
-
111
-
-
79958109354
-
Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity
-
Quercioli A, Pataky Z, Vincenti G, Makoundou V, Di Marzo V, Montecucco F, Carballo S, Thomas A, Staub C, Steffens S, Seimbille Y, Golay A, Ratib O, Harsch E, Mach F, Schindler TH. Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity. Eur Heart J 32: 1369-1378, 2011.
-
(2011)
Eur Heart J
, vol.32
, pp. 1369-1378
-
-
Quercioli, A.1
Pataky, Z.2
Vincenti, G.3
Makoundou, V.4
Di Marzo, V.5
Montecucco, F.6
Carballo, S.7
Thomas, A.8
Staub, C.9
Steffens, S.10
Seimbille, Y.11
Golay, A.12
Ratib, O.13
Harsch, E.14
Mach, F.15
Schindler, T.H.16
-
112
-
-
0035958637
-
Cannabinoid activation of recombinant and endogenous vanilloid receptors
-
Ralevic V, Kendall DA, Jerman JC, Middlemiss DN, Smart D. Cannabinoid activation of recombinant and endogenous vanilloid receptors. Eur J Pharmacol 424: 211-219, 2001.
-
(2001)
Eur J Pharmacol
, vol.424
, pp. 211-219
-
-
Ralevic, V.1
Kendall, D.A.2
Jerman, J.C.3
Middlemiss, D.N.4
Smart, D.5
-
113
-
-
84860360738
-
Biogenesis of the preprotein translocase of the outer mitochondrial membrane: Protein kinase A phosphorylates the precursor of Tom40 and impairs its import
-
Rao S, Schmidt O, Harbauer AB, Schonfisch B, Guiard B, Pfanner N, Meisinger C. Biogenesis of the preprotein translocase of the outer mitochondrial membrane: protein kinase A phosphorylates the precursor of Tom40 and impairs its import. Mol Biol Cell 23: 1618-1627, 2012.
-
(2012)
Mol Biol Cell
, vol.23
, pp. 1618-1627
-
-
Rao, S.1
Schmidt, O.2
Harbauer, A.B.3
Schonfisch, B.4
Guiard, B.5
Pfanner, N.6
Meisinger, C.7
-
114
-
-
84863413790
-
Improved insulin sensitivity after treatment with PPARgamma and PPARalpha ligands is mediated by genetically modulated transcripts
-
Rasouli N, Kern PA, Elbein SC, Sharma NK, Das SK. Improved insulin sensitivity after treatment with PPARgamma and PPARalpha ligands is mediated by genetically modulated transcripts. Pharmacogenet Genomics 22: 484-497, 2012.
-
(2012)
Pharmacogenet Genomics
, vol.22
, pp. 484-497
-
-
Rasouli, N.1
Kern, P.A.2
Elbein, S.C.3
Sharma, N.K.4
Das, S.K.5
-
115
-
-
1842866963
-
CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
-
Ravinet Trillou C, Delgorge C, Menet C, Arnone M, Soubrie P. CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity. Int J Obes Relat Metab Disord 28: 640-648, 2004.
-
(2004)
Int J Obes Relat Metab Disord
, vol.28
, pp. 640-648
-
-
Ravinet Trillou, C.1
Delgorge, C.2
Menet, C.3
Arnone, M.4
Soubrie, P.5
-
116
-
-
24944487186
-
Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells
-
Reilly CA, Johansen ME, Lanza DL, Lee J, Lim JO, Yost GS. Calcium-dependent and independent mechanisms of capsaicin receptor (TRPV1)-mediated cytokine production and cell death in human bronchial epithelial cells. J Biochem Mol Toxicol 19: 266-275, 2005.
-
(2005)
J Biochem Mol Toxicol
, vol.19
, pp. 266-275
-
-
Reilly, C.A.1
Johansen, M.E.2
Lanza, D.L.3
Lee, J.4
Lim, J.O.5
Yost, G.S.6
-
117
-
-
73649100201
-
Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity
-
Ritov VB, Menshikova EV, Azuma K, Wood R, Toledo FG, Goodpaster BH, Ruderman NB, Kelley DE. Deficiency of electron transport chain in human skeletal muscle mitochondria in type 2 diabetes mellitus and obesity. Am J Physiol Endocrinol Metab 298: E49-E58, 2010.
-
(2010)
Am J Physiol Endocrinol Metab
, vol.298
-
-
Ritov, V.B.1
Menshikova, E.V.2
Azuma, K.3
Wood, R.4
Toledo, F.G.5
Goodpaster, B.H.6
Ruderman, N.B.7
Kelley, D.E.8
-
118
-
-
12144275294
-
Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
-
Ritov VB, Menshikova EV, He J, Ferrell RE, Goodpaster BH, Kelley DE. Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Diabetes 54: 8-14, 2005.
-
(2005)
Diabetes
, vol.54
, pp. 8-14
-
-
Ritov, V.B.1
Menshikova, E.V.2
He, J.3
Ferrell, R.E.4
Goodpaster, B.H.5
Kelley, D.E.6
-
119
-
-
79953304942
-
Mitochondrial dysfunction links ceramide activated HRK expression and cell death
-
Rizvi F, Heimann T, Herrnreiter A, O'Brien WJ. Mitochondrial dysfunction links ceramide activated HRK expression and cell death. PLoS One 6: e18137, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Rizvi, F.1
Heimann, T.2
Herrnreiter, A.3
O'Brien, W.J.4
-
120
-
-
33745280979
-
Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor gamma independently of cannabinoid receptors 1 and 2
-
Rockwell CE, Snider NT, Thompson JT, Vanden Heuvel JP, Kaminski NE. Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor gamma independently of cannabinoid receptors 1 and 2. Mol Pharmacol 70: 101-111, 2006.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 101-111
-
-
Rockwell, C.E.1
Snider, N.T.2
Thompson, J.T.3
Vanden Heuvel, J.P.4
Kaminski, N.E.5
-
121
-
-
34347391646
-
Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone
-
Rong JX, Qiu Y, Hansen MK, Zhu L, Zhang V, Xie M, Okamoto Y, Mattie MD, Higashiyama H, Asano S, Strum JC, Ryan TE. Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone. Diabetes 56: 1751-1760, 2007.
-
(2007)
Diabetes
, vol.56
, pp. 1751-1760
-
-
Rong, J.X.1
Qiu, Y.2
Hansen, M.K.3
Zhu, L.4
Zhang, V.5
Xie, M.6
Okamoto, Y.7
Mattie, M.D.8
Higashiyama, H.9
Asano, S.10
Strum, J.C.11
Ryan, T.E.12
-
122
-
-
42249115682
-
Endocannabinoids, sperm functions and energy metabolism
-
Rossato M. Endocannabinoids, sperm functions and energy metabolism. Mol Cell Endocrinol 286: S31-S35, 2008.
-
(2008)
Mol Cell Endocrinol
, vol.286
-
-
Rossato, M.1
-
123
-
-
60849124534
-
Cannabidiol targets mitochondria to regulate intracellular Ca2+ levels
-
Ryan D, Drysdale AJ, Lafourcade C, Pertwee RG, Platt B. Cannabidiol targets mitochondria to regulate intracellular Ca2+ levels. J Neurosci 29: 2053-2063, 2009.
-
(2009)
J Neurosci
, vol.29
, pp. 2053-2063
-
-
Ryan, D.1
Drysdale, A.J.2
Lafourcade, C.3
Pertwee, R.G.4
Platt, B.5
-
124
-
-
35649015179
-
The orphan receptor GPR55 is a novel cannabinoid receptor
-
Ryberg E, Larsson N, Sjogren S, Hjorth S, Hermansson NO, Leonova J, Elebring T, Nilsson K, Drmota T, Greasley PJ. The orphan receptor GPR55 is a novel cannabinoid receptor. Br J Pharmacol 152: 1092-1101, 2007.
-
(2007)
Br J Pharmacol
, vol.152
, pp. 1092-1101
-
-
Ryberg, E.1
Larsson, N.2
Sjogren, S.3
Hjorth, S.4
Hermansson, N.O.5
Leonova, J.6
Elebring, T.7
Nilsson, K.8
Drmota, T.9
Greasley, P.J.10
-
125
-
-
25444515720
-
Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons
-
Ryu H, Lee J, Impey S, Ratan RR, Ferrante RJ. Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons. Proc Natl Acad Sci USA 102: 13915-13920, 2005.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13915-13920
-
-
Ryu, H.1
Lee, J.2
Impey, S.3
Ratan, R.R.4
Ferrante, R.J.5
-
126
-
-
33847253038
-
Regulation of carnitine palmitoyltransferase I (CPT-Ialpha) gene expression by the peroxisome proliferator activated receptor gamma coactivator (PGC-1) isoforms
-
Sadana P, Zhang Y, Song S, Cook GA, Elam MB, Park EA. Regulation of carnitine palmitoyltransferase I (CPT-Ialpha) gene expression by the peroxisome proliferator activated receptor gamma coactivator (PGC-1) isoforms. Mol Cell Endocrinol 267: 6-16, 2007.
-
(2007)
Mol Cell Endocrinol
, vol.267
, pp. 6-16
-
-
Sadana, P.1
Zhang, Y.2
Song, S.3
Cook, G.A.4
Elam, M.B.5
Park, E.A.6
-
127
-
-
84875841356
-
The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55
-
Sharir H, Console-Bram L, Mundy C, Popoff SN, Kapur A, Abood ME. The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55. J Neuroimmune Pharmacol 7: 856-865, 2012.
-
(2012)
J Neuroimmune Pharmacol
, vol.7
, pp. 856-865
-
-
Sharir, H.1
Console-Bram, L.2
Mundy, C.3
Popoff, S.N.4
Kapur, A.5
Abood, M.E.6
-
128
-
-
0031911402
-
The cannabinoid agonist Win55,212-2 inhibits calcium channels by receptor-mediated and direct pathways in cultured rat hippocampal neurons
-
Shen M, Thayer SA. The cannabinoid agonist Win55,212-2 inhibits calcium channels by receptor-mediated and direct pathways in cultured rat hippocampal neurons. Brain Res 783: 77-84, 1998.
-
(1998)
Brain Res
, vol.783
, pp. 77-84
-
-
Shen, M.1
Thayer, S.A.2
-
129
-
-
34548499520
-
The endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species
-
Siegmund SV, Qian T, de Minicis S, Harvey-White J, Kunos G, Vinod KY, Hungund B, Schwabe RF. The endocannabinoid 2-arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species. FASEB J 21: 2798-2806, 2007.
-
(2007)
FASEB J
, vol.21
, pp. 2798-2806
-
-
Siegmund, S.V.1
Qian, T.2
de Minicis, S.3
Harvey-White, J.4
Kunos, G.5
Vinod, K.Y.6
Hungund, B.7
Schwabe, R.F.8
-
130
-
-
84857394125
-
Alteration in mitochondrial thiol enhances calcium ion dependent membrane permeability transition and dysfunction in vitro: A cross-talk between mtThiol, Ca(2+), and ROS
-
Singh BK, Tripathi M, Pandey PK, Kakkar P. Alteration in mitochondrial thiol enhances calcium ion dependent membrane permeability transition and dysfunction in vitro: a cross-talk between mtThiol, Ca(2+), and ROS. Mol Cell Biochem 357: 373-385, 2011.
-
(2011)
Mol Cell Biochem
, vol.357
, pp. 373-385
-
-
Singh, B.K.1
Tripathi, M.2
Pandey, P.K.3
Kakkar, P.4
-
131
-
-
17844411014
-
Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH)
-
Sipe JC, Waalen J, Gerber A, Beutler E. Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH). Int J Obes (Lond) 29: 755-759, 2005.
-
(2005)
Int J Obes (Lond)
, vol.29
, pp. 755-759
-
-
Sipe, J.C.1
Waalen, J.2
Gerber, A.3
Beutler, E.4
-
132
-
-
84888419979
-
Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle
-
Smith ME, Tippetts TS, Brassfield ES, Tucker BJ, Ockey A, Swensen AC, Anthonymuthu TS, Washburn TD, Kane DA, Prince JT, Bikman BT. Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle. Biochem J 456: 427-439, 2013.
-
(2013)
Biochem J
, vol.456
, pp. 427-439
-
-
Smith, M.E.1
Tippetts, T.S.2
Brassfield, E.S.3
Tucker, B.J.4
Ockey, A.5
Swensen, A.C.6
Anthonymuthu, T.S.7
Washburn, T.D.8
Kane, D.A.9
Prince, J.T.10
Bikman, B.T.11
-
133
-
-
53949086484
-
Temporal and site-specific brain alterations in CB1 receptor binding in high fat diet-induced obesity in C57Bl/6 mice
-
South T, Huang XF. Temporal and site-specific brain alterations in CB1 receptor binding in high fat diet-induced obesity in C57Bl/6 mice. J Neuroendocrinol 20: 1288-1294, 2008.
-
(2008)
J Neuroendocrinol
, vol.20
, pp. 1288-1294
-
-
South, T.1
Huang, X.F.2
-
134
-
-
21344444333
-
A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
-
Sparks LM, Xie H, Koza RA, Mynatt R, Hulver MW, Bray GA, Smith SR. A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. Diabetes 54: 1926-1933, 2005.
-
(2005)
Diabetes
, vol.54
, pp. 1926-1933
-
-
Sparks, L.M.1
Xie, H.2
Koza, R.A.3
Mynatt, R.4
Hulver, M.W.5
Bray, G.A.6
Smith, S.R.7
-
135
-
-
0035816410
-
Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide
-
Sprague J, Harrison C, Rowbotham DJ, Smart D, Lambert DG. Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide. Eur J Pharmacol 423: 121-125, 2001.
-
(2001)
Eur J Pharmacol
, vol.423
, pp. 121-125
-
-
Sprague, J.1
Harrison, C.2
Rowbotham, D.J.3
Smart, D.4
Lambert, D.G.5
-
136
-
-
40149084635
-
Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet
-
Starowicz KM, Cristino L, Matias I, Capasso R, Racioppi A, Izzo AA, Di Marzo V. Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet. Obesity (Silver Spring) 16: 553-565, 2008.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 553-565
-
-
Starowicz, K.M.1
Cristino, L.2
Matias, I.3
Capasso, R.4
Racioppi, A.5
Izzo, A.A.6
Di Marzo, V.7
-
137
-
-
0037049237
-
Neonatal anandamide treatment results in prolonged mitochondrial damage in the vanilloid receptor type 1-immunoreactive B-type neurons of the rat trigeminal ganglion
-
Szoke E, Czeh G, Szolcsanyi J, Seress L. Neonatal anandamide treatment results in prolonged mitochondrial damage in the vanilloid receptor type 1-immunoreactive B-type neurons of the rat trigeminal ganglion. Neuroscience 115: 805-814, 2002.
-
(2002)
Neuroscience
, vol.115
, pp. 805-814
-
-
Szoke, E.1
Czeh, G.2
Szolcsanyi, J.3
Seress, L.4
-
138
-
-
77955286305
-
Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity
-
Tam J, Vemuri VK, Liu J, Batkai S, Mukhopadhyay B, Godlewski G, Osei-Hyiaman D, Ohnuma S, Ambudkar SV, Pickel J, Makriyannis A, Kunos G. Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity. J Clin Invest 120: 2953-2966, 2010.
-
(2010)
J Clin Invest
, vol.120
, pp. 2953-2966
-
-
Tam, J.1
Vemuri, V.K.2
Liu, J.3
Batkai, S.4
Mukhopadhyay, B.5
Godlewski, G.6
Osei-Hyiaman, D.7
Ohnuma, S.8
Ambudkar, S.V.9
Pickel, J.10
Makriyannis, A.11
Kunos, G.12
-
139
-
-
9144271149
-
Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome
-
Tanaka T, Yamamoto J, Iwasaki S, Asaba H, Hamura H, Ikeda Y, Watanabe M, Magoori K, Ioka RX, Tachibana K, Watanabe Y, Uchiyama Y, Sumi K, Iguchi H, Ito S, Doi T, Hamakubo T, Naito M, Auwerx J, Yanagisawa M, Kodama T, Sakai J. Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome. Proc Natl Acad Sci USA 100: 15924-15929, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15924-15929
-
-
Tanaka, T.1
Yamamoto, J.2
Iwasaki, S.3
Asaba, H.4
Hamura, H.5
Ikeda, Y.6
Watanabe, M.7
Magoori, K.8
Ioka, R.X.9
Tachibana, K.10
Watanabe, Y.11
Uchiyama, Y.12
Sumi, K.13
Iguchi, H.14
Ito, S.15
Doi, T.16
Hamakubo, T.17
Naito, M.18
Auwerx, J.19
Yanagisawa, M.20
Kodama, T.21
Sakai, J.22
more..
-
140
-
-
79955958008
-
Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance
-
Taschler U, Radner FP, Heier C, Schreiber R, Schweiger M, Schoiswohl G, Preiss-Landl K, Jaeger D, Reiter B, Koefeler HC, Wojciechowski J, Theussl C, Penninger JM, Lass A, Haemmerle G, Zechner R, Zimmermann R. Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J Biol Chem 286: 17467-17477, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 17467-17477
-
-
Taschler, U.1
Radner, F.P.2
Heier, C.3
Schreiber, R.4
Schweiger, M.5
Schoiswohl, G.6
Preiss-Landl, K.7
Jaeger, D.8
Reiter, B.9
Koefeler, H.C.10
Wojciechowski, J.11
Theussl, C.12
Penninger, J.M.13
Lass, A.14
Haemmerle, G.15
Zechner, R.16
Zimmermann, R.17
-
141
-
-
50949092455
-
Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes
-
Tedesco L, Valerio A, Cervino C, Cardile A, Pagano C, Vettor R, Pasquali R, Carruba MO, Marsicano G, Lutz B, Pagotto U, Nisoli E. Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes. Diabetes 57: 2028-2036, 2008.
-
(2008)
Diabetes
, vol.57
, pp. 2028-2036
-
-
Tedesco, L.1
Valerio, A.2
Cervino, C.3
Cardile, A.4
Pagano, C.5
Vettor, R.6
Pasquali, R.7
Carruba, M.O.8
Marsicano, G.9
Lutz, B.10
Pagotto, U.11
Nisoli, E.12
-
142
-
-
78049307571
-
Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: The role of eNOS, p38 MAPK, and AMPK pathways
-
Tedesco L, Valerio A, Dossena M, Cardile A, Ragni M, Pagano C, Pagotto U, Carruba MO, Vettor R, Nisoli E. Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways. Diabetes 59: 2826-2836, 2010.
-
(2010)
Diabetes
, vol.59
, pp. 2826-2836
-
-
Tedesco, L.1
Valerio, A.2
Dossena, M.3
Cardile, A.4
Ragni, M.5
Pagano, C.6
Pagotto, U.7
Carruba, M.O.8
Vettor, R.9
Nisoli, E.10
-
144
-
-
33847080728
-
AMP-activated protein kinase in metabolic control and insulin signaling
-
Towler MC, Hardie DG. AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res 100: 328-341, 2007.
-
(2007)
Circ Res
, vol.100
, pp. 328-341
-
-
Towler, M.C.1
Hardie, D.G.2
-
145
-
-
34547588219
-
Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: Evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents
-
Turner N, Bruce CR, Beale SM, Hoehn KL, So T, Rolph MS, Cooney GJ. Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents. Diabetes 56: 2085-2092, 2007.
-
(2007)
Diabetes
, vol.56
, pp. 2085-2092
-
-
Turner, N.1
Bruce, C.R.2
Beale, S.M.3
Hoehn, K.L.4
So, T.5
Rolph, M.S.6
Cooney, G.J.7
-
146
-
-
77956022194
-
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole body oxygen consumption
-
Ussher JR, Koves TR, Cadete VJ, Zhang L, Jaswal JS, Swyrd SJ, Lopaschuk DG, Proctor SD, Keung W, Muoio DM, Lopaschuk GD. Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole body oxygen consumption. Diabetes 59: 2453-2464, 2010.
-
(2010)
Diabetes
, vol.59
, pp. 2453-2464
-
-
Ussher, J.R.1
Koves, T.R.2
Cadete, V.J.3
Zhang, L.4
Jaswal, J.S.5
Swyrd, S.J.6
Lopaschuk, D.G.7
Proctor, S.D.8
Keung, W.9
Muoio, D.M.10
Lopaschuk, G.D.11
-
147
-
-
23044517184
-
Cannabinoids and ceramide: Two lipids acting hand-by-hand
-
Velasco G, Galve-Roperh I, Sanchez C, Blazquez C, Haro A, Guzman M. Cannabinoids and ceramide: two lipids acting hand-by-hand. Life Sci 77: 1723-1731, 2005.
-
(2005)
Life Sci
, vol.77
, pp. 1723-1731
-
-
Velasco, G.1
Galve-Roperh, I.2
Sanchez, C.3
Blazquez, C.4
Haro, A.5
Guzman, M.6
-
148
-
-
0031568242
-
Control of hepatic fatty acid oxidation by 5'-AMP-activated protein kinase involves a malonyl-CoAdependent and a malonyl-CoA-independent mechanism
-
Velasco G, Geelen MJ, Guzman M. Control of hepatic fatty acid oxidation by 5'-AMP-activated protein kinase involves a malonyl-CoAdependent and a malonyl-CoA-independent mechanism. Arch Biochem Biophys 337: 169-175, 1997.
-
(1997)
Arch Biochem Biophys
, vol.337
, pp. 169-175
-
-
Velasco, G.1
Geelen, M.J.2
Guzman, M.3
-
149
-
-
39949083025
-
Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells
-
Villena J, Henriquez M, Torres V, Moraga F, Diaz-Elizondo J, Arredondo C, Chiong M, Olea-Azar C, Stutzin A, Lavandero S, Quest AF. Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells. Free Radic Biol Med 44: 1146-1160, 2008.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 1146-1160
-
-
Villena, J.1
Henriquez, M.2
Torres, V.3
Moraga, F.4
Diaz-Elizondo, J.5
Arredondo, C.6
Chiong, M.7
Olea-Azar, C.8
Stutzin, A.9
Lavandero, S.10
Quest, A.F.11
-
150
-
-
0032982520
-
The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells
-
Waksman Y, Olson JM, Carlisle SJ, Cabral GA. The central cannabinoid receptor (CB1) mediates inhibition of nitric oxide production by rat microglial cells. J Pharmacol Exp Ther 288: 1357-1366, 1999.
-
(1999)
J Pharmacol Exp Ther
, vol.288
, pp. 1357-1366
-
-
Waksman, Y.1
Olson, J.M.2
Carlisle, S.J.3
Cabral, G.A.4
-
151
-
-
3242726868
-
Effects of N-acylethanolamines on mitochondrial energetics and permeability transition
-
Wasilewski M, Wieckowski MR, Dymkowska D, Wojtczak L. Effects of N-acylethanolamines on mitochondrial energetics and permeability transition. Biochim Biophys Acta 1657: 151-163, 2004.
-
(2004)
Biochim Biophys Acta
, vol.1657
, pp. 151-163
-
-
Wasilewski, M.1
Wieckowski, M.R.2
Dymkowska, D.3
Wojtczak, L.4
-
152
-
-
59849098608
-
Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipidinduced insulin resistance in rat skeletal muscle cells
-
Watson ML, Coghlan M, Hundal HS. Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipidinduced insulin resistance in rat skeletal muscle cells. Biochem J 417: 791-801, 2009.
-
(2009)
Biochem J
, vol.417
, pp. 791-801
-
-
Watson, M.L.1
Coghlan, M.2
Hundal, H.S.3
-
153
-
-
0032936642
-
Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors
-
Williams CM, Kirkham TC. Anandamide induces overeating: mediation by central cannabinoid (CB1) receptors. Psychopharmacology (Berl) 143: 315-317, 1999.
-
(1999)
Psychopharmacology (Berl)
, vol.143
, pp. 315-317
-
-
Williams, C.M.1
Kirkham, T.C.2
-
154
-
-
0033949848
-
Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle
-
Winder WW, Holmes BF, Rubink DS, Jensen EB, Chen M, Holloszy JO. Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle. J Appl Physiol (1985) 88: 2219-2226, 2000.
-
(2000)
J Appl Physiol (1985)
, vol.88
, pp. 2219-2226
-
-
Winder, W.W.1
Holmes, B.F.2
Rubink, D.S.3
Jensen, E.B.4
Chen, M.5
Holloszy, J.O.6
-
155
-
-
0036670602
-
Effect of multiple phosphorylation events on the transcription factors FKHR, FKHRL1 and AFX
-
Woods YL, Rena G. Effect of multiple phosphorylation events on the transcription factors FKHR, FKHRL1 and AFX. Biochem Soc Trans 30: 391-397, 2002.
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 391-397
-
-
Woods, Y.L.1
Rena, G.2
-
156
-
-
67650096801
-
Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome
-
Yang G, Badeanlou L, Bielawski J, Roberts AJ, Hannun YA, Samad F. Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome. Am J Physiol Endocrinol Metab 297: E211-E224, 2009.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.297
-
-
Yang, G.1
Badeanlou, L.2
Bielawski, J.3
Roberts, A.J.4
Hannun, Y.A.5
Samad, F.6
-
157
-
-
0037184925
-
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
Yu C, Chen Y, Cline GW, Zhang D, Zong H, Wang Y, Bergeron R, Kim JK, Cushman SW, Cooney GJ, Atcheson B, White MF, Kraegen EW, Shulman GI. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem 277: 50230-50236, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
Zhang, D.4
Zong, H.5
Wang, Y.6
Bergeron, R.7
Kim, J.K.8
Cushman, S.W.9
Cooney, G.J.10
Atcheson, B.11
White, M.F.12
Kraegen, E.W.13
Shulman, G.I.14
-
158
-
-
78651356681
-
Anandamide inhibits oxidative phosphorylation in isolated liver mitochondria
-
Zaccagnino P, Corcelli A, Baronio M, Lorusso M. Anandamide inhibits oxidative phosphorylation in isolated liver mitochondria. FEBS Lett 585: 429-434, 2011.
-
(2011)
FEBS Lett
, vol.585
, pp. 429-434
-
-
Zaccagnino, P.1
Corcelli, A.2
Baronio, M.3
Lorusso, M.4
-
159
-
-
84863863361
-
The endocannabinoid 2-arachidonoylglicerol decreases calcium induced cytochrome c release from liver mitochondria
-
Zaccagnino P, D'Oria S, Romano LL, Di Venere A, Sardanelli AM, Lorusso M. The endocannabinoid 2-arachidonoylglicerol decreases calcium induced cytochrome c release from liver mitochondria. J Bioenerg Biomembr 44: 273-280, 2012.
-
(2012)
J Bioenerg Biomembr
, vol.44
, pp. 273-280
-
-
Zaccagnino, P.1
D'Oria, S.2
Romano, L.L.3
Di Venere, A.4
Sardanelli, A.M.5
Lorusso, M.6
-
160
-
-
67650756178
-
N-arachidonylglycine causes ROS production and cytochrome c release in liver mitochondria
-
Zaccagnino P, Saltarella M, D'Oria S, Corcelli A, Saponetti MS, Lorusso M. N-arachidonylglycine causes ROS production and cytochrome c release in liver mitochondria. Free Radic Biol Med 47: 585-592, 2009.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 585-592
-
-
Zaccagnino, P.1
Saltarella, M.2
D'Oria, S.3
Corcelli, A.4
Saponetti, M.S.5
Lorusso, M.6
-
161
-
-
79956099507
-
Mitochondrial dysfunction during in vitro hepatocyte steatosis is reversed by omega-3 fatty acid-induced up-regulation of mitofusin 2
-
Zhang Y, Jiang L, Hu W, Zheng Q, Xiang W. Mitochondrial dysfunction during in vitro hepatocyte steatosis is reversed by omega-3 fatty acid-induced up-regulation of mitofusin 2. Metabolism 60: 767-775, 2011.
-
(2011)
Metabolism
, vol.60
, pp. 767-775
-
-
Zhang, Y.1
Jiang, L.2
Hu, W.3
Zheng, Q.4
Xiang, W.5
-
162
-
-
84892434340
-
Effects of cannabinoid receptor 1 (brain) on lipid accumulation by transcriptional control of CPT1A and CPT1B
-
Aug 5. doi: 10.1111/ age.12078. [Epub ahead of print]
-
Zhang YF, Yuan ZQ, Song DG, Zhou XH, Wang YZ. Effects of cannabinoid receptor 1 (brain) on lipid accumulation by transcriptional control of CPT1A and CPT1B. Anim Genet 2013 Aug 5. doi: 10.1111/ age.12078. [Epub ahead of print].
-
(2013)
Anim Genet
-
-
Zhang, Y.F.1
Yuan, Z.Q.2
Song, D.G.3
Zhou, X.H.4
Wang, Y.Z.5
-
163
-
-
84879881379
-
Activation of type 2 cannabinoid receptors (CB2R) promotes fatty acid oxidation through the SIRT1/PGC-1alpha pathway
-
Zheng X, Sun T, Wang X. Activation of type 2 cannabinoid receptors (CB2R) promotes fatty acid oxidation through the SIRT1/PGC-1alpha pathway. Biochem Biophys Res Commun 436: 377-381, 2013.
-
(2013)
Biochem Biophys Res Commun
, vol.436
, pp. 377-381
-
-
Zheng, X.1
Sun, T.2
Wang, X.3
-
164
-
-
0037077692
-
CB1 cannabinoid receptor-mediated tyrosine phosphorylation of focal adhesion kinase-related non-kinase
-
Zhou D, Song ZH. CB1 cannabinoid receptor-mediated tyrosine phosphorylation of focal adhesion kinase-related non-kinase. FEBS Lett 525: 164-168, 2002.
-
(2002)
FEBS Lett
, vol.525
, pp. 164-168
-
-
Zhou, D.1
Song, Z.H.2
-
165
-
-
0347949531
-
Anandamide initiates Ca(2+) signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells
-
Zoratti C, Kipmen-Korgun D, Osibow K, Malli R, Graier WF. Anandamide initiates Ca(2+) signaling via CB2 receptor linked to phospholipase C in calf pulmonary endothelial cells. Br J Pharmacol 140: 1351-1362, 2003.
-
(2003)
Br J Pharmacol
, vol.140
, pp. 1351-1362
-
-
Zoratti, C.1
Kipmen-Korgun, D.2
Osibow, K.3
Malli, R.4
Graier, W.F.5
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