Cannabidiol targets mitochondria to regulate intracellular ca2+ levels

Journal of Neuroscience

Volumn 29, Issue 7, 2009, Pages 2053-2063

  Ryan, Duncan ^a   Drysdale, Alison J ^a   Lafourcade, Carlos ^a,b   Pertwee, Roger G ^a   Platt, Bettina ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

ATP synthase; Cannabinoids; Excitotoxicity; Hippocampus; Neuroprotection

Indexed keywords

7 CHLORO 5 (2 CHLOROPHENYL) 1,5 DIHYDRO 4,1 BENZOTHIAZEPIN 2(3H) ONE; CALCIUM; CANNABIDIOL; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; CYCLOSPORIN A; FURA 2 ACETOXYMETHYL ESTER; HYDROGEN PEROXIDE; OLIGOMYCIN; POTASSIUM; POTASSIUM CHANNEL BLOCKING AGENT; RYANODINE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN MITOCHONDRION; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CELL DEATH; CONTROLLED STUDY; CYTOSOL; DRUG MECHANISM; DRUG TARGETING; ENDOPLASMIC RETICULUM; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR IMAGING; NERVE CELL CULTURE; NERVE CELL EXCITABILITY; NEUROBLASTOMA CELL; NEUROMODULATION; NEUROPHYSIOLOGY; NEUROPROTECTION; NONHUMAN; OSCILLATION; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT;

EID: 60849124534     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4212-08.2009     Document Type: Article

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