-
1
-
-
0037048167
-
Overweight and obesity as determinants of cardiovascular risk: The Framingham experience
-
Wilson PW, D'Agostino RB, Sullivan L, Parise H, Kannel WB: Overweight and obesity as determinants of cardiovascular risk: the Framingham experience. Arch Intern Med 162:1867-1872, 2002
-
(2002)
Arch Intern Med
, vol.162
, pp. 1867-1872
-
-
Wilson, P.W.1
D'Agostino, R.B.2
Sullivan, L.3
Parise, H.4
Kannel, W.B.5
-
2
-
-
0037078283
-
Body mass index, waist circumference, and health risk: Evidence in support of current National Institutes of Health guidelines
-
Janssen I, Katzmarzyk PT, Ross R: Body mass index, waist circumference, and health risk: evidence in support of current National Institutes of Health guidelines. Arch Intern Med 162:2074-2079, 2002
-
(2002)
Arch Intern Med
, vol.162
, pp. 2074-2079
-
-
Janssen, I.1
Katzmarzyk, P.T.2
Ross, R.3
-
3
-
-
0035799806
-
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
-
Tuomilehto J, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Eanne-Parikka P, Keinanen-Kiukaanniemi S, Laakso M, Louheranta A, Rastas M, Salminen V, Uusitupa M: Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344:1343-1350, 2001
-
(2001)
N Engl J Med
, vol.344
, pp. 1343-1350
-
-
Tuomilehto, J.1
Lindstrom, J.2
Eriksson, J.G.3
Valle, T.T.4
Hamalainen, H.5
Eanne-Parikka, P.6
Keinanen-Kiukaanniemi, S.7
Laakso, M.8
Louheranta, A.9
Rastas, M.10
Salminen, V.11
Uusitupa, M.12
-
4
-
-
10844295087
-
Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery
-
Sjöström L, Lindroos AK, Peltonen M, Torgerson J, Bouchard C, Carlsson B, Dahlgren S, Larsson B, Narbro K, Sjöström CD, Sullivan M, Wedel H: Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med 351:2683-2693, 2004
-
(2004)
N Engl J Med
, vol.351
, pp. 2683-2693
-
-
Sjöström, L.1
Lindroos, A.K.2
Peltonen, M.3
Torgerson, J.4
Bouchard, C.5
Carlsson, B.6
Dahlgren, S.7
Larsson, B.8
Narbro, K.9
Sjöström, C.D.10
Sullivan, M.11
Wedel, H.12
-
5
-
-
0035185205
-
Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats
-
Jamshidi N, Taylor DA: Anandamide administration into the ventromedial hypothalamus stimulates appetite in rats. Br J Pharmacol 134:1151-1154, 2001
-
(2001)
Br J Pharmacol
, vol.134
, pp. 1151-1154
-
-
Jamshidi, N.1
Taylor, D.A.2
-
6
-
-
0036607403
-
Observational analysis of feeding induced by Delta9-THC and anandamide
-
Williams CM, Kirkham TC: Observational analysis of feeding induced by Delta9-THC and anandamide. Physiol Behav 76:241-250, 2002
-
(2002)
Physiol Behav
, vol.76
, pp. 241-250
-
-
Williams, C.M.1
Kirkham, T.C.2
-
7
-
-
0032936642
-
Anandamide induces overeating: Mediation by central cannabinoid receptors
-
Williams CM, Kirkham TC: Anandamide induces overeating: mediation by central cannabinoid receptors. Psychopharmacology (Berl) 143:315-317, 1999
-
(1999)
Psychopharmacology (Berl)
, vol.143
, pp. 315-317
-
-
Williams, C.M.1
Kirkham, T.C.2
-
8
-
-
0037352188
-
Endogenous cannabinoid system as a modulator of food intake
-
Cota D, Marsicano G, Lutz B, Vicennati V, Stalla GK, Pasquali R, Pagotto U: Endogenous cannabinoid system as a modulator of food intake. Int J Obes Relat Metab Disord 27:289-301, 2003
-
(2003)
Int J Obes Relat Metab Disord
, vol.27
, pp. 289-301
-
-
Cota, D.1
Marsicano, G.2
Lutz, B.3
Vicennati, V.4
Stalla, G.K.5
Pasquali, R.6
Pagotto, U.7
-
9
-
-
0036669295
-
Tetrahydrocannabinol and endocannabinoids in feeding and appetite
-
Berry EM, Mechoulam R: Tetrahydrocannabinol and endocannabinoids in feeding and appetite. Pharmacol Ther 95:185-190, 2002
-
(2002)
Pharmacol Ther
, vol.95
, pp. 185-190
-
-
Berry, E.M.1
Mechoulam, R.2
-
10
-
-
0242268553
-
The molecular logic of endocannabinoid signalling
-
Piomelli D: The molecular logic of endocannabinoid signalling. Nat Rev Neurosci 4:873-884, 2003
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 873-884
-
-
Piomelli, D.1
-
11
-
-
18444376760
-
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
-
Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG: International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev 54:161-202, 2002
-
(2002)
Pharmacol Rev
, vol.54
, pp. 161-202
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
Cabral, G.4
Casellas, P.5
Devane, W.A.6
Felder, C.C.7
Herkenham, M.8
Mackie, K.9
Martin, B.R.10
Mechoulam, R.11
Pertwee, R.G.12
-
12
-
-
0035848818
-
Leptin-regulated endocannabinoids are involved in maintaining food intake
-
Di Marzo V, Goparaju SK, Wang L, Liu J, Batkai S, Jarai Z, Fezza F, Miura GI, Palmiter RD, Sugiura T, Kunos G: Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 410:822-825, 2001
-
(2001)
Nature
, vol.410
, pp. 822-825
-
-
Di Marzo, V.1
Goparaju, S.K.2
Wang, L.3
Liu, J.4
Batkai, S.5
Jarai, Z.6
Fezza, F.7
Miura, G.I.8
Palmiter, R.D.9
Sugiura, T.10
Kunos, G.11
-
13
-
-
0037131098
-
Down-regulation of cannabinoid-1 (CB-1) receptors in specific extrahypothalamic regions of rats with dietary obesity: A role for endogenous cannabinoids in driving appetite for palatable food?
-
Harrold JA, Elliott JC, King PJ, Widdowson PS, Williams G: Down-regulation of cannabinoid-1 (CB-1) receptors in specific extrahypothalamic regions of rats with dietary obesity: a role for endogenous cannabinoids in driving appetite for palatable food? Brain Res 952:232-238, 2002
-
(2002)
Brain Res
, vol.952
, pp. 232-238
-
-
Harrold, J.A.1
Elliott, J.C.2
King, P.J.3
Widdowson, P.S.4
Williams, G.5
-
14
-
-
1842866963
-
CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
-
Ravinet TC, Delgorge C, Menet C, Arnone M, Soubrie P: CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity. Int J Obes Relat Metab Disord 28:640-648, 2004
-
(2004)
Int J Obes Relat Metab Disord
, vol.28
, pp. 640-648
-
-
Ravinet, T.C.1
Delgorge, C.2
Menet, C.3
Arnone, M.4
Soubrie, P.5
-
15
-
-
0037304290
-
Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice
-
Ravinet TC, Arnone M, Delgorge C, Gonalons N, Keane P, Maffrand JP, Soubrie P: Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice. Am J Physiol 284:R345-R353, 2003
-
(2003)
Am J Physiol
, vol.284
-
-
Ravinet, T.C.1
Arnone, M.2
Delgorge, C.3
Gonalons, N.4
Keane, P.5
Maffrand, J.P.6
Soubrie, P.7
-
16
-
-
85047690626
-
The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
-
Cota D, Marsicano G, Tschöp M, Grubler Y, Flachskamm C, Schubert M, Auer D, Yassouridis A, Thöne-Reineke C, Ortmann S, Tomassoni F, Cervino C, Nisoli E, Linthorst AC, Pasquali R, Lutz B, Stalla GK, Pagotto U: The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 112:423-431, 2003
-
(2003)
J Clin Invest
, vol.112
, pp. 423-431
-
-
Cota, D.1
Marsicano, G.2
Tschöp, M.3
Grubler, Y.4
Flachskamm, C.5
Schubert, M.6
Auer, D.7
Yassouridis, A.8
Thöne-Reineke, C.9
Ortmann, S.10
Tomassoni, F.11
Cervino, C.12
Nisoli, E.13
Linthorst, A.C.14
Pasquali, R.15
Lutz, B.16
Stalla, G.K.17
Pagotto, U.18
-
17
-
-
0037374766
-
The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells
-
Bensaid M, Gary-Bobo M, Esclangon A, Maffrand JP, Le Fur G, Oury-Donat F, Soubrie P: The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells. Mol Pharmacol 63:908-914, 2003
-
(2003)
Mol Pharmacol
, vol.63
, pp. 908-914
-
-
Bensaid, M.1
Gary-Bobo, M.2
Esclangon, A.3
Maffrand, J.P.4
Le Fur, G.5
Oury-Donat, F.6
Soubrie, P.7
-
18
-
-
20944436157
-
Endocannabinoid activation at hepatic CB(1) receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
-
Osei-Hyiaman D, Depetrillo M, Pacher P, Liu J, Radaeva S, Batkai S, Harvey-White J, Mackie K, Offertaler L, Wang L, Kunos G: Endocannabinoid activation at hepatic CB(1) receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest 115:1298-1305, 2005
-
(2005)
J Clin Invest
, vol.115
, pp. 1298-1305
-
-
Osei-Hyiaman, D.1
Depetrillo, M.2
Pacher, P.3
Liu, J.4
Radaeva, S.5
Batkai, S.6
Harvey-White, J.7
Mackie, K.8
Offertaler, L.9
Wang, L.10
Kunos, G.11
-
19
-
-
17144382751
-
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
-
Van Gaal LF, Rissanen AM, Scheen AJ, Ziegler O, Rössner S: Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 365:1389-1397, 2005
-
(2005)
Lancet
, vol.365
, pp. 1389-1397
-
-
Van Gaal, L.F.1
Rissanen, A.M.2
Scheen, A.J.3
Ziegler, O.4
Rössner, S.5
-
20
-
-
3042571675
-
Cannabinoid receptor antagonists and obesity
-
Black SC: Cannabinoid receptor antagonists and obesity. Curr Opin Investig Drugs 5:389-394, 2004
-
(2004)
Curr Opin Investig Drugs
, vol.5
, pp. 389-394
-
-
Black, S.C.1
-
21
-
-
0037380664
-
Association between adiponectin and mediators of inflammation in obese women
-
Engeli S, Feldpausch M, Gorzelniak K, Hartwig F, Heintze U, Janke J, Möhlig M, Pfeiffer AF, Luft FC, Sharma AM: Association between adiponectin and mediators of inflammation in obese women. Diabetes 52:942-947, 2003
-
(2003)
Diabetes
, vol.52
, pp. 942-947
-
-
Engeli, S.1
Feldpausch, M.2
Gorzelniak, K.3
Hartwig, F.4
Heintze, U.5
Janke, J.6
Möhlig, M.7
Pfeiffer, A.F.8
Luft, F.C.9
Sharma, A.M.10
-
22
-
-
14644395574
-
Weight loss and the renin-angiotensin-aldosterone system
-
Engeli S, Böhnke J, Gorzelniak K, Janke J, Schling P, Bader M, Luft FC, Sharma AM: Weight loss and the renin-angiotensin-aldosterone system. Hypertension 45:356-362, 2005
-
(2005)
Hypertension
, vol.45
, pp. 356-362
-
-
Engeli, S.1
Böhnke, J.2
Gorzelniak, K.3
Janke, J.4
Schling, P.5
Bader, M.6
Luft, F.C.7
Sharma, A.M.8
-
23
-
-
0036266179
-
Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors
-
Janke J, Engeli S, Gorzelniak K, Luft FC, Sharma AM: Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors. Diabetes 51:1699-1707, 2002
-
(2002)
Diabetes
, vol.51
, pp. 1699-1707
-
-
Janke, J.1
Engeli, S.2
Gorzelniak, K.3
Luft, F.C.4
Sharma, A.M.5
-
24
-
-
0037417989
-
Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice
-
Wang L, Liu J, Harvey-White J, Zimmer A, Kunos G: Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice. Proc Natl Acad Sci USA 100:1393-1398, 2003
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 1393-1398
-
-
Wang, L.1
Liu, J.2
Harvey-White, J.3
Zimmer, A.4
Kunos, G.5
-
25
-
-
20044388537
-
Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility
-
Maccarrone M, Fride E, Bisogno T, Bari M, Cascio MG, Battista N, Finazzi AA, Suris R, Mechoulam R, Di Marzo V: Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility. Mol Hum Reprod 11:21-28, 2005
-
(2005)
Mol Hum Reprod
, vol.11
, pp. 21-28
-
-
Maccarrone, M.1
Fride, E.2
Bisogno, T.3
Bari, M.4
Cascio, M.G.5
Battista, N.6
Finazzi, A.A.7
Suris, R.8
Mechoulam, R.9
Di Marzo, V.10
-
26
-
-
0038305991
-
Leptin activates the anandamide hydrolase promoter in human T lymphocytes through STAT3
-
Maccarrone M, Di Rienzo M, Finazzi-Agro A, Rossi A: Leptin activates the anandamide hydrolase promoter in human T lymphocytes through STAT3. J Biol Chem 278:13318-13324, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 13318-13324
-
-
Maccarrone, M.1
Di Rienzo, M.2
Finazzi-Agro, A.3
Rossi, A.4
-
27
-
-
17844411014
-
Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH)
-
Sipe JC, Waalen J, Gerber A, Beutler E: Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH). Int J Obes Relat Metab Disord 29:755-759, 2005
-
(2005)
Int J Obes Relat Metab Disord
, vol.29
, pp. 755-759
-
-
Sipe, J.C.1
Waalen, J.2
Gerber, A.3
Beutler, E.4
-
28
-
-
0033555839
-
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
-
Ledent C, Valverde O, Cossu G, Petitet F, Aubert JF, Beslot F, Bohme GA, Imperato A, Pedrazzini T, Roques BP, Vassart G, Fratta W, Parmentier M: Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 283:401-404, 1999
-
(1999)
Science
, vol.283
, pp. 401-404
-
-
Ledent, C.1
Valverde, O.2
Cossu, G.3
Petitet, F.4
Aubert, J.F.5
Beslot, F.6
Bohme, G.A.7
Imperato, A.8
Pedrazzini, T.9
Roques, B.P.10
Vassart, G.11
Fratta, W.12
Parmentier, M.13
-
29
-
-
20844454912
-
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension
-
Batkai S, Pacher P, Osei-Hyiaman D, Radaeva S, Liu J, Harvey-White J, Offertaler L, Mackie K, Rudd MA, Bukoski RD, Kunos G: Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation 110:1996-2002, 2004
-
(2004)
Circulation
, vol.110
, pp. 1996-2002
-
-
Batkai, S.1
Pacher, P.2
Osei-Hyiaman, D.3
Radaeva, S.4
Liu, J.5
Harvey-White, J.6
Offertaler, L.7
Mackie, K.8
Rudd, M.A.9
Bukoski, R.D.10
Kunos, G.11
-
30
-
-
19444369394
-
Blood pressure regulation by endocannabinoids and their receptors
-
Pacher P, Batkai S, Kunos G: Blood pressure regulation by endocannabinoids and their receptors. Neuropharmacol 48:1130-1138, 2005
-
(2005)
Neuropharmacol
, vol.48
, pp. 1130-1138
-
-
Pacher, P.1
Batkai, S.2
Kunos, G.3
-
32
-
-
11144355734
-
The endogenous cannabinoid system protects against colonic inflammation
-
Massa F, Marsicano G, Hermann H, Cannich A, Monory K, Cravatt BF, Ferri GL, Sibaev A, Storr M, Lutz B: The endogenous cannabinoid system protects against colonic inflammation. J Clin Invest 113:1202-1209, 2004
-
(2004)
J Clin Invest
, vol.113
, pp. 1202-1209
-
-
Massa, F.1
Marsicano, G.2
Hermann, H.3
Cannich, A.4
Monory, K.5
Cravatt, B.F.6
Ferri, G.L.7
Sibaev, A.8
Storr, M.9
Lutz, B.10
-
33
-
-
0345735772
-
A novel synthetic cannabinoid derivative inhibits inflammatory liver damage via negative cytokine regulation
-
Lavon I, Sheinin T, Meilin S, Biton E, Weksler A, Efroni G, Bar-Joseph A, Fink G, Avraham A: A novel synthetic cannabinoid derivative inhibits inflammatory liver damage via negative cytokine regulation. Mol Pharmacol 64:1334-1341, 2003
-
(2003)
Mol Pharmacol
, vol.64
, pp. 1334-1341
-
-
Lavon, I.1
Sheinin, T.2
Meilin, S.3
Biton, E.4
Weksler, A.5
Efroni, G.6
Bar-Joseph, A.7
Fink, G.8
Avraham, A.9
-
34
-
-
0346350327
-
The cannabinoid system and immune modulation
-
Klein TW, Newton C, Larsen K, Lu L, Ferions I, Nong L, Friedman H: The cannabinoid system and immune modulation. J Leukoc Biol 74:486-496, 2003
-
(2003)
J Leukoc Biol
, vol.74
, pp. 486-496
-
-
Klein, T.W.1
Newton, C.2
Larsen, K.3
Lu, L.4
Ferions, I.5
Nong, L.6
Friedman, H.7
-
35
-
-
0344082866
-
CB1- and CB2-cannabinoid receptor-independent lipolysis induced by WIN 55,212-2 in male rat adipocytes
-
Nieri P, Greco R, Adinolfi B, Breschi MC, Martinotti E, Nannetti C, Podesta A: CB1- and CB2-cannabinoid receptor-independent lipolysis induced by WIN 55,212-2 in male rat adipocytes. Naunyn Schmiedebergs Arch Pharmacol 368:352-359, 2003
-
(2003)
Naunyn Schmiedebergs Arch Pharmacol
, vol.368
, pp. 352-359
-
-
Nieri, P.1
Greco, R.2
Adinolfi, B.3
Breschi, M.C.4
Martinotti, E.5
Nannetti, C.6
Podesta, A.7
-
36
-
-
9444265979
-
Potential modulation of plasma ghrelin and glucagon-like peptide-1 by anorexigenic cannabinoid compounds, SR141716A (rimonabant) and oleoylethanolamide
-
Cani PD, Montoya ML, Neyrinck AM, Delzenne NM, Lambert DM: Potential modulation of plasma ghrelin and glucagon-like peptide-1 by anorexigenic cannabinoid compounds, SR141716A (rimonabant) and oleoylethanolamide. Br J Nutr 92:757-761, 2004
-
(2004)
Br J Nutr
, vol.92
, pp. 757-761
-
-
Cani, P.D.1
Montoya, M.L.2
Neyrinck, A.M.3
Delzenne, N.M.4
Lambert, D.M.5
-
37
-
-
8744249918
-
The cannabinoid CB1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin
-
Tucci SA, Rogers EK, Korbonits M, Kirkham TC: The cannabinoid CB1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin. Br J Pharmacol 143:520-523, 2004
-
(2004)
Br J Pharmacol
, vol.143
, pp. 520-523
-
-
Tucci, S.A.1
Rogers, E.K.2
Korbonits, M.3
Kirkham, T.C.4
|