Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle

Biochemical Journal

Volumn 456, Issue 3, 2013, Pages 427-439

  Smith, Melissa E ^a   Tippetts, Trevor S ^a   Brassfield, Eric S ^a   Tucker, Braden J ^a   Ockey, Adelaide ^a   Swensen, Adam C ^b   Anthonymuthu, Tamil S ^b   Washburn, Trevor D ^a   Kane, Daniel A ^c   Prince, John T ^b   Bikman, Benjamin T ^a  

^a BRIGHAM YOUNG UNIVERSITY   (United States)

^b N243 Eyring Science Center   (United States)

^c ST FRANCIS XAVIER UNIVERSITY   (Canada)

Author keywords

Ceramide; Dynamin related protein 1 (Drp1); Metabolic disruption; Mitochondrial fission; Mitochondrion

Indexed keywords

CERAMIDE; DYNAMIN RELATED PROTEIN 1; HYDROGEN PEROXIDE; PROTEIN; PROTEIN KINASE B; UNCLASSIFIED DRUG; DNM1L PROTEIN, MOUSE; DYNAMIN; INSULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL STRUCTURE; CONTROLLED STUDY; DRUG EFFECT; GASTROCNEMIUS MUSCLE; INSULIN RESISTANCE; MALE; MITOCHONDRIAL FISSION; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; MUSCLE FUNCTION; MUSCLE MITOCHONDRION; MYOTUBE; NONHUMAN; OBESITY; OBSERVATIONAL STUDY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SKELETAL MUSCLE; WEIGHT GAIN; ANIMAL; CELL LINE; DRUG EFFECTS; METABOLISM; MITOCHONDRIAL DYNAMICS; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TOXICITY;

ANIMALS; CELL LINE; CERAMIDES; DYNAMINS; HYDROGEN PEROXIDE; INSULIN; MALE; MICE; MITOCHONDRIA, MUSCLE; MITOCHONDRIAL DYNAMICS; MUSCLE FIBERS, SKELETAL; OXYGEN CONSUMPTION; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 84888419979     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130807     Document Type: Article

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