-
1
-
-
0032695482
-
Annual deaths attributable to obesity in the United States
-
Allison DB, Fontaine KR, Manson JE, Stevens J, and VanItallie TB (1999) Annual deaths attributable to obesity in the United States. J Am Med Assoc 282:1530-1538.
-
(1999)
J Am Med Assoc
, vol.282
, pp. 1530-1538
-
-
Allison, D.B.1
Fontaine, K.R.2
Manson, J.E.3
Stevens, J.4
VanItallie, T.B.5
-
2
-
-
0033515761
-
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
-
Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, et al. (1999) Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257:79-83.
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 79-83
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
Takahashi, M.4
Maeda, K.5
Miyagawa, J.6
Hotta, K.7
Shimomura, I.8
Nakamura, T.9
Miyaoka, K.10
-
3
-
-
0030738512
-
Selective inhibition ofsucrose and ethanol intake by SR 141716, an antagonist of central carmabinoid (CB1) receptors
-
Arnone M, Maruani J, Chaperon F, Thiebot MH, Poncelet M, Soubrie P, and Le Fur G (1997) Selective inhibition ofsucrose and ethanol intake by SR 141716, an antagonist of central carmabinoid (CB1) receptors. Psychopharmacology 132:104-106.
-
(1997)
Psychopharmacology
, vol.132
, pp. 104-106
-
-
Arnone, M.1
Maruani, J.2
Chaperon, F.3
Thiebot, M.H.4
Poncelet, M.5
Soubrie, P.6
Le Fur, G.7
-
4
-
-
0012677323
-
SR141716 reduces weight gain in obese Zucker rats by regulating hyperphagia and activating fatty acid oxidation
-
Arnone M, Millet L, Desclaux MF, Delgorge C, Keane P, Maffrand JP and Soubrié P SR141716 reduces weight gain in obese Zucker rats by regulating hyperphagia and activating fatty acid oxidation. Br J Pharmacol.
-
Br J Pharmacol
-
-
Arnone, M.1
Millet, L.2
Desclaux, M.F.3
Delgorge, C.4
Keane, P.5
Maffrand, J.P.6
Soubrié, P.7
-
5
-
-
0033436355
-
Insulin and leptin: Dual adiposity signals to the brain for the regulation of food intake and body weight
-
Baskin DG, Figlewicz LD, Seeley RJ, Woods SC, Porte D Jr, and Schwartz MW (1999) Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight. Brain Res 848:114-123.
-
(1999)
Brain Res
, vol.848
, pp. 114-123
-
-
Baskin, D.G.1
Figlewicz, L.D.2
Seeley, R.J.3
Woods, S.C.4
Porte D., Jr.5
Schwartz, M.W.6
-
6
-
-
0034881391
-
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
-
Berg AH, Combs TP, Du X, Brownlee M, and Scherer PE (2001) The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 7:947-953.
-
(2001)
Nat Med
, vol.7
, pp. 947-953
-
-
Berg, A.H.1
Combs, T.P.2
Du, X.3
Brownlee, M.4
Scherer, P.E.5
-
7
-
-
0030826705
-
A selective inverse-agonist for central cannabinoid receptor inhibits mitogen-activated protein kinase activation stimulated by insulin and insulin-like growth factor 1
-
Bouaboula M, Perrachon S, Milligan L, Canat X, Rinaldi-Carmona M, Portier M, Barth F, Calandras B, Pecceu F, Lupker J, et al. (1997) A selective inverse-agonist for central cannabinoid receptor inhibits mitogen-activated protein kinase activation stimulated by insulin and insulin-like growth factor 1. J Biol Chem 272:22330-22339.
-
(1997)
J Biol Chem
, vol.272
, pp. 22330-22339
-
-
Bouaboula, M.1
Perrachon, S.2
Milligan, L.3
Canat, X.4
Rinaldi-Carmona, M.5
Portier, M.6
Barth, F.7
Calandras, B.8
Pecceu, F.9
Lupker, J.10
-
8
-
-
0029401988
-
Insulin normalization as an approach to the pharmacological treatment of obesity
-
Campfield LA, Smith FJ, Mackie G, Tenenbaum R, Sassano ML, Mullin J, Kaiser K, and Kierstead RW (1995) Insulin normalization as an approach to the pharmacological treatment of obesity. Obes Res 3(Suppl 4):591s-603s.
-
(1995)
Obes Res
, vol.3
, Issue.SUPPL. 4
-
-
Campfield, L.A.1
Smith, F.J.2
Mackie, G.3
Tenenbaum, R.4
Sassano, M.L.5
Mullin, J.6
Kaiser, K.7
Kierstead, R.W.8
-
9
-
-
0034074194
-
Patent focus on new anti-obesity agents: September 1999-February 2000
-
Carpino PA (2000) Patent focus on new anti-obesity agents: September 1999-February 2000. Expert Opin Ther Patents 10:819-831.
-
(2000)
Expert Opin Ther Patents
, vol.10
, pp. 819-831
-
-
Carpino, P.A.1
-
10
-
-
0031780582
-
Involvement of central cannabinoid (CB1) receptors in the establishment of place conditioning in rats
-
Chaperon F, Soubrie P, Puech AJ, and Thiebot MH (1998) Involvement of central cannabinoid (CB1) receptors in the establishment of place conditioning in rats. Psychopharmacology 135:324-332.
-
(1998)
Psychopharmacology
, vol.135
, pp. 324-332
-
-
Chaperon, F.1
Soubrie, P.2
Puech, A.J.3
Thiebot, M.H.4
-
11
-
-
0032541111
-
Appetite suppression and weight loss after the cannabinoid antagonist SR 141716
-
Colombo G, Agabio R, Diaz G, Lobina C, Reali R, and Gessa GL (1998) Appetite suppression and weight loss after the cannabinoid antagonist SR 141716. Life Sci 63:L113-L117.
-
(1998)
Life Sci
, vol.63
-
-
Colombo, G.1
Agabio, R.2
Diaz, G.3
Lobina, C.4
Reali, R.5
Gessa, G.L.6
-
12
-
-
0035663963
-
Endogenous glucose production is inhibited by the adipose-derived protein Acrp30
-
Combs TP, Berg AH, Obici S, Scherer PE, and Rossetti L (2001) Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. J Clin Investig 108:1875-1881.
-
(2001)
J Clin Investig
, vol.108
, pp. 1875-1881
-
-
Combs, T.P.1
Berg, A.H.2
Obici, S.3
Scherer, P.E.4
Rossetti, L.5
-
13
-
-
0035848818
-
Leptin-regulated endocannabinoids are involved in maintaining food intake
-
Di Marzo V, Goparaju SK, Wang L, Liu J, Batkai S, Jarai Z, Fezza F, Miura GI, Palmiter RD, Sugiura T, et al. (2001) Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature (Lond) 410:822-825.
-
(2001)
Nature (Lond)
, vol.410
, pp. 822-825
-
-
Di Marzo, V.1
Goparaju, S.K.2
Wang, L.3
Liu, J.4
Batkai, S.5
Jarai, Z.6
Fezza, F.7
Miura, G.I.8
Palmiter, R.D.9
Sugiura, T.10
-
14
-
-
0026597356
-
Gene expression of lipid storage-related enzymes in adipose tissue of the genetically obese Zucker rat. Coordinated increase in transcriptional activity and potentiation by hyperinsulinaemia
-
Dugail I, Quignard-Boulange A, Le Liepvre X, Ardouin B, and Lavau M. (1992) Gene expression of lipid storage-related enzymes in adipose tissue of the genetically obese Zucker rat. Coordinated increase in transcriptional activity and potentiation by hyperinsulinaemia. Biochem J 281:607-611.
-
(1992)
Biochem J
, vol.281
, pp. 607-611
-
-
Dugail, I.1
Quignard-Boulange, A.2
Le Liepvre, X.3
Ardouin, B.4
Lavau, M.5
-
15
-
-
0033082380
-
From lesions to leptin: Hypothalamic control of food intake and body weight
-
Elmquist JK, Elias CF, and Saper CB (1999) From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22:221-232.
-
(1999)
Neuron
, vol.22
, pp. 221-232
-
-
Elmquist, J.K.1
Elias, C.F.2
Saper, C.B.3
-
16
-
-
0000935366
-
Diverse roles of adipose tissue in the regulation of systematic metabolism and energy balance
-
Bray GA, Bouchard C, James W eds, Marcel Dekker, New York
-
Fried SK and Russell C (1998) Diverse roles of adipose tissue in the regulation of systematic metabolism and energy balance, in Handbook of Obesity (Bray GA, Bouchard C, James W eds) pp 397-413, Marcel Dekker, New York.
-
(1998)
Handbook of Obesity
, pp. 397-413
-
-
Fried, S.K.1
Russell, C.2
-
17
-
-
0035852760
-
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
-
Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, Bihain BE, and Lodish HF (2001) Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 98:2005-2010.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2005-2010
-
-
Fruebis, J.1
Tsao, T.S.2
Javorschi, S.3
Ebbets-Reed, D.4
Erickson, M.R.5
Yen, F.T.6
Bihain, B.E.7
Lodish, H.F.8
-
18
-
-
0016243979
-
Sublines of mouse 3T3 cells that accumulate lipid
-
Green H and Kehinde O (1973) Sublines of mouse 3T3 cells that accumulate lipid. Cell 1:113-116.
-
(1973)
Cell
, vol.1
, pp. 113-116
-
-
Green, H.1
Kehinde, O.2
-
19
-
-
0034023811
-
Pharmacology ofappetite suppression
-
Halford JC and Blundell JE (2000) Pharmacology ofappetite suppression. Prog Drug Res 54:25-58.
-
(2000)
Prog Drug Res
, vol.54
, pp. 25-58
-
-
Halford, J.C.1
Blundell, J.E.2
-
20
-
-
17544382289
-
AdipoQ is a novel adipose-specific gene dysregulated in obesity
-
Hu E, Liang P, and Spiegelman BM (1996) AdipoQ is a novel adipose-specific gene dysregulated in obesity. J Biol Chem 271:10697-10703.
-
(1996)
J Biol Chem
, vol.271
, pp. 10697-10703
-
-
Hu, E.1
Liang, P.2
Spiegelman, B.M.3
-
21
-
-
0033038418
-
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
-
Kalra SP, Dube MG, Pu S, Xu B, Horvath TL, and Kalra PS (1999) Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocrine Rev 20:68-100.
-
(1999)
Endocrine Rev
, vol.20
, pp. 68-100
-
-
Kalra, S.P.1
Dube, M.G.2
Pu, S.3
Xu, B.4
Horvath, T.L.5
Kalra, P.S.6
-
22
-
-
0017330406
-
Increasing activity of enzymes on pathway of triacylglycerol synthesis during adipose conversion of 3T3 cells
-
Kuri-Harcuch W and Green H (1977) Increasing activity of enzymes on pathway of triacylglycerol synthesis during adipose conversion of 3T3 cells. J Biol Chem 252:2158-2160.
-
(1977)
J Biol Chem
, vol.252
, pp. 2158-2160
-
-
Kuri-Harcuch, W.1
Green, H.2
-
23
-
-
0029980285
-
cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1)
-
Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, and Matsubara K (1996) cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun 221:286-289.
-
(1996)
Biochem Biophys Res Commun
, vol.221
, pp. 286-289
-
-
Maeda, K.1
Okubo, K.2
Shimomura, I.3
Funahashi, T.4
Matsuzawa, Y.5
Matsubara, K.6
-
24
-
-
0032742418
-
The disease burden associated with overweight and obesity
-
Must A, Spadano J, Coakley EH, Field AE, Colditz G, and Dietz WH (1999) The disease burden associated with overweight and obesity. J Am Med Assoc 282:1523-1529.
-
(1999)
J Am Med Assoc
, vol.282
, pp. 1523-1529
-
-
Must, A.1
Spadano, J.2
Coakley, E.H.3
Field, A.E.4
Colditz, G.5
Dietz, W.H.6
-
25
-
-
0029836585
-
Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma
-
Nakano Y, Tobe T, Choi-Miura NH, Mazda T, and Tomita M (1996) Isolation and characterization of GBP28, a novel gelatin-binding protein purified from human plasma. J Biochem 120:803-812.
-
(1996)
J Biochem
, vol.120
, pp. 803-812
-
-
Nakano, Y.1
Tobe, T.2
Choi-Miura, N.H.3
Mazda, T.4
Tomita, M.5
-
26
-
-
0033913223
-
Dynamics of insulin secretion in obesity and diabetes
-
Polonsky KS (2000) Dynamics of insulin secretion in obesity and diabetes. Int J Obes Relat Metab Disord 24 Suppl 2:S29-S31.
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, Issue.SUPPL. 2
-
-
Polonsky, K.S.1
-
28
-
-
0028129936
-
SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
-
Rinaldi-Carmona M, Barth F, Heaulme M, Shire D, Calandra B, Congy C, Martinez S, Maruani J, Neliat G, Caput D, et al. (1994) SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett 350:240-244.
-
(1994)
FEBS Lett
, vol.350
, pp. 240-244
-
-
Rinaldi-Carmona, M.1
Barth, F.2
Heaulme, M.3
Shire, D.4
Calandra, B.5
Congy, C.6
Martinez, S.7
Maruani, J.8
Neliat, G.9
Caput, D.10
-
29
-
-
0037062421
-
Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens
-
Robbe D, Kopf M, Remaury A, Bockaert J, and Manzoni OJ (2002) Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens. Proc Natl Acad Sci USA 99:8384-8388.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 8384-8388
-
-
Robbe, D.1
Kopf, M.2
Remaury, A.3
Bockaert, J.4
Manzoni, O.J.5
-
30
-
-
0028787490
-
A novel serum protein similar to Clq, produced exclusively in adipocytes
-
Scherer PE, Williams S, Fogliano M, Baldini G, and Lodish HF (1995) A novel serum protein similar to Clq, produced exclusively in adipocytes. J Biol Chem 270:26746-26749.
-
(1995)
J Biol Chem
, vol.270
, pp. 26746-26749
-
-
Scherer, P.E.1
Williams, S.2
Fogliano, M.3
Baldini, G.4
Lodish, H.F.5
-
31
-
-
0034999667
-
Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
-
Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, and Tataranni PA (2001) Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 86:1930-1935.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 1930-1935
-
-
Weyer, C.1
Funahashi, T.2
Tanaka, S.3
Hotta, K.4
Matsuzawa, Y.5
Pratley, R.E.6
Tataranni, P.A.7
-
32
-
-
0035851851
-
The hypothalamus and the control of energy homeostasis: Different circuits, different purposes
-
Williams G, Bing C, Cai XJ, Harrold JA, King PJ, and Liu XH (2001) The hypothalamus and the control of energy homeostasis: different circuits, different purposes. Physiol Behav 74:683-701.
-
(2001)
Physiol Behav
, vol.74
, pp. 683-701
-
-
Williams, G.1
Bing, C.2
Cai, X.J.3
Harrold, J.A.4
King, P.J.5
Liu, X.H.6
-
33
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, et al. (2001) The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7:941-946.
-
(2001)
Nat Med
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Terauchi, Y.4
Kubota, N.5
Hara, K.6
Mori, Y.7
Ide, T.8
Murakami, K.9
Tsuboyama-Kasaoka, N.10
|