Anandamide inhibits oxidative phosphorylation in isolated liver mitochondria

FEBS Letters

Volumn 585, Issue 2, 2011, Pages 429-434

  Zaccagnino, Patrizia ^a   Corcelli, Angela ^a   Baronio, Maristella ^a   Lorusso, Michele ^a,b  

^a UNIVERSITY OF BARI   (Italy)

^b CNR   (Italy)

Author keywords

Anandamide; F oF1 ATP synthase; Membrane potential; Mitochondrial respiratory chain

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE HYDROLASE; ANANDAMIDE; HYDROLASE; OLIGOMYCIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HYDROLYSIS; IC 50; LIVER MITOCHONDRION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; ARACHIDONIC ACIDS; ENDOCANNABINOIDS; ENERGY METABOLISM; MEMBRANE POTENTIALS; MITOCHONDRIA, LIVER; OXIDATIVE PHOSPHORYLATION; POLYUNSATURATED ALKAMIDES; PROTON-TRANSLOCATING ATPASES; RATS;

RATTUS;

EID: 78651356681     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.12.032     Document Type: Article

References (42)

1. H.S. Hansen, B. Moesgaard, H.H. Hansen, and G. Petersen N-Acylethanolamines and precursor phospholipids - relation to cell injury Chem. Phys. Lipids 108 2000 135 150
2. Y. Gaoni, and R. Mechoulam The isolation and structure of delta-1-tetrahydrocannabinol and other neutral cannabinoids from hashish J. Am. Chem. Soc. 93 1971 217 224
3. D.E. Epps, P.C. Schmid, V. Natarajan, and H.H. Schmid N-Acylethanolamine accumulation in infarcted myocardium Biochem. Biophys. Res. Commun. 90 1979 628 633
4. B. Moesgaard, J.W. Jaroszewski, and H.S. Hansen Accumulation of N-acyl-ethanolamine phospholipids in rat brains during post-decapitative ischemia: a 31p NMR study J. Lipid Res. 40 1999 515 521 (Pubitemid 29116155)
5. H.H. Hansen, S.H. Hansen, A. Schousboe, and H.S. Hansen Determination of the phospholipid precursor of anandamide and other N-acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons J. Neurochem. 75 2000 861 871 (Pubitemid 30485471)
6. S. Muthian, D.J. Rademacher, C.T. Roelke, G.J. Gross, and C.J. Hillard Anandamide content is increased and CB1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia Neuroscience 129 2004 743 750 (Pubitemid 39487125)
7. S.D. McAllister, and M. Glass CB(1) and CB(2) receptor-mediated signalling: a focus on endocannabinoids Prostaglandins Leukot. Essent. Fatty Acids 66 2002 161 171 (Pubitemid 34743592)
8. R.G. Pertwee Cannabinoid receptors and pain Prog. Neurobiol. 63 2001 569 611
9. A.C. Howlett, F. Barth, T.I. Bonner, G. Cabral, P. Casellas, W.A. Devane, C.C. Felder, M. Herkenham, K. Mackie, B.R. Martin, R. Mechoulam, and R.G. Pertwee International Union of Pharmacology. XXVII. Classification of cannabinoid receptors Pharmacol. Rev. 54 2002 161 202 (Pubitemid 34575709)
10. K. Starowicz, S. Nigam, and V. Di Marzo Biochemistry and pharmacology of endovanilloids Pharmacol. Ther. 114 2007 13 33 (Pubitemid 46498161)
11. D. Centonze, L. Battistini, and M. Maccarrone The endocannabinoid system in peripheral lymphocytes as a mirror of neuroinflammatory diseases Curr. Pharm. Des. 14 2008 2370 2372
12. I. Katona, and T.F. Freund Endocannabinoid signaling as a synaptic circuit breaker in neurological disease Nat. Med. 14 2008 923 930
13. H. Schwarz, F.J. Blanco, and M. Lotz Anadamide, an endogenous cannabinoid receptor agonist inhibits lymphocyte proliferation and induces apoptosis J. Neuroimmunol. 55 1994 107 115 (Pubitemid 24356812)
14. L. De Petrocellis, D. Melck, A. Palmisano, T. Bisogno, C. Laezza, M. Bifulco, and V. Di Marzo The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation Proc. Natl. Acad. Sci. USA 95 1998 8375 8380 (Pubitemid 28326120)
15. K.P. Sarker, S. Obara, M. Nakata, I. Kitajima, and I. Maruyama Anandamide induces apoptosis of PC-12 cells: involvement of superoxide and caspase-3 FEBS Lett. 472 2000 39 44 (Pubitemid 30224582)
16. V.A. Movsesyan, B.A. Stoica, A.G. Yakovlev, S.M. Knoblach, P.Mt. Lea, I. Cernak, R. Vink, and A.I. Faden Anandamide-induced cell death in primary neuronal cultures: role of calpain and caspase pathways Cell Death Differ. 11 2004 1121 1132 (Pubitemid 39341638)
17. M. Maccarrone, and A. Finazzi-Agro The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis Cell Death Differ. 10 2003 946 955 (Pubitemid 37069472)
18. N. Ueda, R.A. Puffenbarger, S. Yamamoto, and D.G. Deutsch The fatty acid amide hydrolase (FAAH) Chem. Phys. Lipids 108 2000 107 121 (Pubitemid 34743595)
19. P.C. Schmid, M.L. Zuzarte-Augustin, and H.H. Schmid Properties of rat liver N-acylethanolamine amidohydrolase J. Biol. Chem. 260 1985 14145 14149 (Pubitemid 16197481)
20. F. Desarnaud, H. Cadas, and D. Piomelli Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization J. Biol. Chem. 270 1995 6030 6035
21. K. Katayama, N. Ueda, Y. Kurahashi, H. Suzuki, S. Yamamoto, and I. Kato Distribution of anandamide amidohydrolase in rat tissues with special reference to small intestine Biochim. Biophys. Acta 1347 1997 212 218 (Pubitemid 27368114)
22. K.P. Sarker, and I. Maruyama Anandamide induces cell death independently of cannabinoid receptors or vanilloid receptor 1: possible involvement of lipid rafts Cell. Mol. Life Sci. 60 2003 1200 1208 (Pubitemid 36791921)
23. K.K. Biswas, K.P. Sarker, K. Abeyama, K. Kawahara, S. Iino, Y. Otsubo, K. Saigo, H. Izumi, T. Hashiguchi, M. Yamakuchi, K. Yamaji, R. Endo, K. Suzuki, H. Imaizumi, and I. Maruyama Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosis Hepatology 38 2003 1167 1177 (Pubitemid 37314825)
24. S.V. Siegmund, H. Uchinami, Y. Osawa, D.A. Brenner, and R.F. Schwabe Anandamide induces necrosis in primary hepatic stellate cells Hepatology 41 2005 1085 1095 (Pubitemid 40593916)
25. K.P. Sarker, K.K. Biswas, M. Yamakuchi, K.Y. Lee, T. Hahiguchi, M. Kracht, I. Kitajima, and I. Maruyama ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death J. Neurochem. 85 2003 50 61 (Pubitemid 36389694)
26. M. Maccarrone Involvement of the Endocannabinoid System in Cancer. In Endocannabinoids: The Brain and Body's Marijiuana and Beyond 2006 CRC Press Boca Raton pp. 451-456
27. M. Rossato, F. Ion Popa, M. Ferigo, G. Clari, and C. Foresta Human sperm express cannabinoid receptor Cb1, the activation of which inhibits motility, acrosome reaction, and mitochondrial function J. Clin. Endocrinol. Metab. 90 2005 984 991 (Pubitemid 40279224)
28. D. Ryan, A.J. Drysdale, C. Lafourcade, R.G. Pertwee, and B. Platt Cannabidiol targets mitochondria to regulate intracellular Ca2+ levels J. Neurosci. 29 2009 2053 2063
29. D.E. Epps, J.W. Palmer, H.H. Schmid, and D.R. Pfeiffer Inhibition of permeability-dependent Ca2+ release from mitochondria by N-acylethanolamines, a class of lipids synthesized in ischemic heart tissue J. Biol. Chem. 257 1982 1383 1391
30. M. Wasilewski, M.R. Wieckowski, D. Dymkowska, and L. Wojtczak Effects of N-acylethanolamines on mitochondrial energetics and permeability transition Biochim. Biophys. Acta 1657 2004 151 163 (Pubitemid 38952876)
31. A. Athanasiou, A.B. Clarke, A.E. Turner, N.M. Kumaran, S. Vakilpour, P.A. Smith, D. Bagiokou, T.D. Bradshaw, A.D. Westwell, L. Fang, D.N. Lobo, C.S. Costantinescu, V. Calabrese, A. Loesch, S.P. Alexander, R.H. Clothier, D.A. Kendall, and T.E. Bates Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death Biochem. Biophys. Res. Commun. 364 2007 131 137 (Pubitemid 47610668)
32. A. Ito, T. Ogishima, W. Ou, T. Omura, H. Aoyagi, S. Lee, H. Mihara, and N. Izumiya Effects of synthetic model peptides resembling the extension peptides of mitochondrial enzyme precursors on import of the precursors into mitochondria J. Biochem. 98 1985 1571 1582 (Pubitemid 16169191)
33. M. Kates Techniques of lipidology R.H. Burdon, P.H. van Knippenberg, Laboratory Techniques in Biochemistry and Molecular Biology Burdon 1986 Elsevier Amsterdam 100 110
34. M. Di Paola, T. Cocco, and M. Lorusso Ceramide interaction with the respiratory chain of heart mitochondria Biochemistry 39 2000 6660 6668 (Pubitemid 30353998)
35. F. Zanotti, G. Raho, A. Gaballo, and S. Papa Inhibitory and anchoring domains in the ATPase inhibitor protein IF1 of bovine heart mitochondrial ATP synthase J. Bioenerg. Biomembr. 36 2004 447 457 (Pubitemid 39491330)
36. P. Zaccagnino, M. Saltarella, S. D'Oria, A. Corcelli, M.S. Saponetti, and M. Lorusso N-Arachidonylglycine causes ROS production and cytochrome c release in liver mitochondria Free Radic. Biol. Med. 47 2009 585 592
37. G. Catanzaro, C. Rapino, S. Oddi, and M. Maccarrone Anandamide increases swelling and reduces calcium sensitivity of mitochondria Biochem. Biophys. Res. Commun. 388 2009 439 442
38. A. Baracca, S. Barogi, V. Carelli, G. Lenaz, and G. Solaini Catalytic activities of mitochondrial ATP synthase in patients with mitochondrial DNA T8993G mutation in the ATPase 6 gene encoding subunit a J. Biol. Chem. 275 2000 4177 4182 (Pubitemid 30094652)
39. S.V. Siegmund, E. Seki, Y. Osawa, H. Uchinami, B.F. Cravatt, and R.F. Schwabe Fatty acid amide hydrolase determines anandamide-induced cell death in the liver J. Biol. Chem. 281 2006 10431 10438 (Pubitemid 43864582)
40. B. Das, M.O. Mondragon, M. Sadeghian, V.B. Hatcher, and A.J. Norin A novel ligand in lymphocyte-mediated cytotoxicity: expression of the beta subunit of H+ transporting ATP synthase on the surface of tumor cell lines J. Exp. Med. 180 1994 273 281 (Pubitemid 24181076)
41. T.L. Moser, M.S. Stack, I. Asplin, J.J. Enghild, P. Hojrup, L. Everitt, S. Hubchak, H.W. Schnaper, and S.V. Pizzo Angiostatin binds ATP synthase on the surface of human endothelial cells Proc. Natl. Acad. Sci. USA 96 1999 2811 2816 (Pubitemid 29148800)
42. M. Bifulco, C. Laezza, P. Gazzerro, and F. Pentimalli Endocannabinoids as emerging suppressors of angiogenesis and tumor invasion (review) Oncol. Rep. 17 2007 813 816