TNF-α induces mitochondrial dysfunction in 3T3-L1 adipocytes

Molecular and Cellular Endocrinology

Volumn 328, Issue 1-2, 2010, Pages 63-69

  Chen, Xiao Hui ^a   Zhao, Ya Ping ^b   Xue, Mei ^c   Ji, Chen Bo ^a   Gao, Chun Lin ^a   Zhu, Jin Gai ^a   Qin, Da Ni ^a   Kou, Chun Zhao ^a   Qin, Xiao Hong ^c   Tong, Mei Ling ^a   Guo, Xi Rong ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b The 82th Hospital of the People's Liberation Army   (China)

^c TAIZHOU PEOPLE S HOSPITAL   (China)

Author keywords

3T3 L1 adipocytes; Insulin resistance; Mitochondrial dysfunction; Mitochondrial morphology; Reactive oxygen species; TNF

Indexed keywords

ADENOSINE TRIPHOSPHATE; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL PROTEIN DRP1; MITOCHONDRIAL PROTEIN MFN1; MITOCHONDRIAL PROTEIN MFN2; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; BIOGENESIS; CELL DENSITY; CELL STRUCTURE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENERGY METABOLISM; ENZYME SYNTHESIS; GENE DOSAGE; GLUCOSE TRANSPORT; INSULIN RESISTANCE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; DNA COPY NUMBER VARIATIONS; DNA, MITOCHONDRIAL; DRUG EVALUATION, PRECLINICAL; GLUCOSE; INSULIN; INSULIN RESISTANCE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; REACTIVE OXYGEN SPECIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77956342883     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2010.07.005     Document Type: Article

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