Alteration in mitochondrial thiol enhances calcium ion dependent membrane permeability transition and dysfunction in vitro: A cross-talk between mtThiol, Ca2+, and ROS

Molecular and Cellular Biochemistry

Volumn 357, Issue 1-2, 2011, Pages 373-385

  Singh, Brijesh Kumar ^a,b   Tripathi, Madhulika ^a   Pandey, Pramod Kumar ^b   Kakkar, Poonam ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b BUNDELKHAND UNIVERSITY   (India)

Author keywords

Calcium overload; Membrane permeability transition; Mitochondrial thiol; Reactive oxygen species

Indexed keywords

CALCIUM ION; CYCLOSPORIN A; CYTOCHROME C; PYRIDINE NUCLEOTIDE; REACTIVE OXYGEN METABOLITE; THIOL; 1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'-TETRAACETIC ACID; APOPTOSIS REGULATORY PROTEIN; CALCIUM; CARRIER PROTEIN; CYCLOSPORIN; DRUG DERIVATIVE; EGTAZIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; THIOL DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CALCIUM HOMEOSTASIS; CONTROLLED STUDY; DEPOLARIZATION; ELECTRON TRANSPORT; FLUORESCENCE; IN VITRO STUDY; MALE; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION SWELLING; NONHUMAN; OXIDATIVE STRESS; RAT; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CELL MEMBRANE PERMEABILITY; DRUG EFFECT; LIVER MITOCHONDRION; METABOLISM; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATION REDUCTION REACTION; PATHOLOGY; SECRETION; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CALCIUM; CELL MEMBRANE PERMEABILITY; CYCLOSPORINE; EGTAZIC ACID; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, LIVER; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SULFHYDRYL COMPOUNDS;

EID: 84857394125     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-011-0908-0     Document Type: Article

References (48)

1. Duszynski J, Koziel R, Brutkowski W, Szczepanowska J, Zablocki K (2006) The regulatory role of mitochondria in capacitative calcium entry. Biochim Biophys Acta 1757(5-6):380-387 (Pubitemid 43993862)
2. Romagnoli A, Aguiari P, De Stefani D, Leo S, Marchi S, Rimessi A, Zecchini E, Pinton P, Rizzuto R (2007) Endoplasmic reticulum/mitochondria calcium cross-talk. Novartis Found Symp 287:122-131
3. Bernardi P, Petronilli V (1996) The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal. J Bioenerg Biomembr 28:131-138 (Pubitemid 26131526)
4. Dong Z, Saikumar P, Weinberg JM, Venkatachalam MA (2006) Calcium in cell injury and death. Annu Rev Pathol 1:405-434
5. Kaasik A, Safiulina D, Zharkovsky A, Veksler V (2006) Regulation of mitochondrial matrix volume. Am J Physiol Cell Physiol 292(1):C157-C163 (Pubitemid 46127307)
6. Kakkar P, Singh BK (2007) Mitochondria: a hub of redox activities and cellular distress control. Mol Cell Biochem 305: 235-253 (Pubitemid 47517185)
7. Droge W (2002) Free radicals in the physiological control of cell function. Physiol Rev 82:47-95 (Pubitemid 34654215)
8. Yuan L, Kaplowitz N (2009) Glutathione in liver disease and hepatotoxicity. Mol Aspects Med 30:29-41
9. Ghosh A, Sil PC (2009) Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-kB pathway: role of a novel plant protein. Chem Biol Interact 177: 96-106
10. Franco R, Cidlowski JA (2009) Apoptosis and glutathione: beyond an antioxidant. Cell Death Differ 16:1303-1314
11. 2+ as a key regulator of cell life and death. Cell Death Differ 14(7):1267-1274 (Pubitemid 46965258)
12. Hollis BW (2005) Calcium and disease. In: Weaver CM, Heaney RP (eds) Calcium in human health. Humana Press, Totowa, NJ, pp 313-425
13. Frezza C, Cipolat S, Scorrano L (2007) Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblast. Nat Protoc 2:287-292
14. Gusdon AM, Chen J, Votyakova TV, Mathews CE (2009) Quantification, localization, and tissue specificities of mouse mitochondrial reactive oxygen species production. Methods Enzymol 456:439-457
15. Nieminen AL, Ramshesh VK, Lemasters JJ (2008) Use of fluorescent reporters to measure mitochondrial membrane potential and the mitochondrial permeability transition. In: Dykens JA, Will Y (eds) Drug induced mitochondrial dysfunction. Wiley, New Jersey, pp 414-431
16. Kruglov AG, Teplova VV, Saris NE (2007) The effect of the lipophilic cation lucigenin on mitochondria depends on the site of its reduction. Biochem Pharmacol 74:545-556 (Pubitemid 47049633)
17. Lowry OH, Rosebough NJ, Farr AL, Randall RJ (1951) Protein measurement with Folin Phenol reagent. J Biol Chem 193: 265-275
18. Estebern-Pretel G, Lopez-Garcia MP (2006) An experimental design for the controlled modulation of intracellular GSH levels in cultured hepatocytes. Free Radic Biol Med 41:610-619
19. Harwood DT, Kettle AJ, Brennan S, Winterbourn CC (2009) Simultaneous determination of reduced glutathione, glutathione disulphide and glutathione sulphonamide in cells and physiological fluids by isotope dilution liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 877:3393-3399
20. Santana DP, Faria PA, Paredes-Gamero EJ, Caires AC, Nantes IL, Rodrigues T (2009) Palladacycles catalyse the oxidation of critical thiols of the mitochondrial membrane proteins and lead to mitochondrial permeabilization and cytochrome c release associated with apoptosis. Biochem J 417:247-256
21. Gonzalez D, Espino J, Bejarano I, Lopez JJ, Rodriguez AB, Pariente JA (2010) Caspase-3 and -9 are activated in human myeloid HL-60 cells by calcium signal. Mol Cell Biochem 333: 151-157
22. Tripathi M, Singh BK, Mishra C, Raissudin S, Kakkar P (2010) Involvement of mitochondria mediated pathways in hepatoprotaction conferred by Fumeria parviflora Lam. extract against nimesulide induced apoptosis in vitro. Toxicol In Vitro 24:495-508
23. Halvey PJ, Hansen JM, Lash LH, Jones DP (2008) Compartmentation of redox signaling and control: discrimination of oxidative stress in mitochondria, cytoplasm, nuclei and endoplasmic reticulum. In: Dykens JA, Will Y (eds) Drug induced mitochondrial dysfunction. Wiley, New Jersey, pp 433-461
24. 2+ concentration by decreasing cellular thiol content in rat thymocytes. Toxicology 262:245-249
25. Mayevsky A, Barbiro-Michaely E (2009) Use of NADH fluorescence to determine mitochondrial function in vivo. Int J Biochem Cell Biol 41:1977-1988
26. Pierce RH, Campbell JS, Stephenson AB, Franklin CC, Chaisson M, Poot M, Kavanagh TJ, Rabinovitch PS, Fausto N (2000) Disruption of redox homeostasis in tumor necrosis factor-induced apoptosis in a murine hepatocyte cell line. Am J Pathol 157:221-236 (Pubitemid 30641739)
27. 2+ accumulation during reoxygenation of rat cardiomyocytes. Am J Physiol Heart Circ Physiol 280:344-353
28. Campbell RV, Yang Y, Wang T, Rachamallu A, Li Y, Watowich SJ, Weinman SA (2009) Effects of hepatitis C core protein on mitochondrial electron transport and production of reactive oxygen species. Methods Enzymol 456:363-380
29. Malinska D, Kudin AP, Debska-Veilhaber G, Veilhaber S, Kunz WS (2009) Quantification of superoxide production by mouse brain and skeletal muscle mitochondria. Methods Enzymol 456:419-437
30. Cohen G, Kesler N (1999) Monoamine oxidase and mitochondrial respiration. J Neurochem 73:2310-2315
31. Fu W, Luo H, Parthasarathy S, Mattson MP (1998) Catecholamines potentiates amyloid b-peptide neurotoxicity: involvement of oxidative stress, mitochondrial dysfunction and perturbed calcium homeostasis. Neurobiol Dis 5:229-243 (Pubitemid 28519153)
32. Kakkar P, Mehrotra S, Vishwanathan PN (1998) Influence of antioxidants on the peroxidative swelling of mitochondria in vitro. Cell Biol Toxicol 14:313-321 (Pubitemid 28467839)
33. Cande C, Vahsen N, Garrido C, Kroemer G (2004) Apoptosisnducing factor (AIF): caspase-independent after all. Cell Death Differ 11(6):591-595 (Pubitemid 38786707)
34. Kowaltowski AJ, Netto LES, Vercesi AE (1998) The thiol specific antioxidant enzyme prevents mitochondria membrane permeability transition. Evidence for the participation of reactive oxygen species in this mechanism. J Biol Chem 273:12766-12769 (Pubitemid 28246830)
35. Kowaltowski AJ, Castilho RF, Vercesi AE (2001) Mitochondrial permeability transition and oxidative stress. FEBS Lett 495: 12-15 (Pubitemid 32367965)
36. 2+ induced membrane permeability transition in brain mitochondria. J Neurochem 79:1237-1245 (Pubitemid 34019801)
37. Mehrotra S, Kakkar P, Vishwanathan PN (1999) Mitochondrial damage by active oxygen species in vitro. Free Radic Biol Med 10:277-285
38. Mehrotra S, Vishwanathan PN, Kakkar P (1993) Influence of some biological response modifiers on swelling of rat liver mitochondria in vitro. Mol Cell Biochem 124:101-106 (Pubitemid 23270848)
39. Lash LH (2008) Mitochondrial GSH transport and intestinal cell injury: a commentary on Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis. Free Radic Biol Med 44:765-767
40. Reed DJ, Savage MK (1995) Influence of metabolic inhibitors on mitochondrial permeability transition and glutathione status. Biochim Biophys Acta 1271:43-50
41. Chernyak BV, Bernardi P (1996) The mitochondrial permeability transition pore is modulated by oxidative agents through both pyridine nucleotides and glutathione at two separate sites. Eur J Biochem 238:623-630 (Pubitemid 26235100)
42. Costantini P, Chernyak BV, Petronilli V, Bernardi P (1996) Modulation of the mitochondrial permeability transition pore by pyridine nucleotides and dithiol oxidation at two different sites. J Biol Chem 271(12):6746-6751 (Pubitemid 26104106)
43. Halestrap AP, Woodfield KY, Connern CP (1997) Oxidative stress, thiol reagents and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase. J Biol Chem 272(6):3346-3354
44. LuC, ArmstrongJS(2007) Roleof calcium and cyclophilin Dinthe regulation of mitochondrial permeabilization induced by glutathione depletion. Biochim Biophys Res Commun 363:572-577
45. Starnes JW, Barnes BD, Olsen ME (2007) Exercise induces a cardiac mitochondrial phenotype that resists apoptotic stimuli. J Appl Physiol 102:1793-1798
46. Jones DP (2006) Disruption of mitochondrial circuitry in oxidative stress. Chem Biol Interact 163:38-53 (Pubitemid 44572221)
47. Raha S, Robinson BH (2000) Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem Sci 25:502-508
48. Kakkar P, Mehrotra S, Vishwanathan PN (1996) tert-BHP induced in vitro swelling of rat liver mitochondria. Mol Cell Biochem 154:39-45 (Pubitemid 26038044)