Δ 9-tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells

British Journal of Pharmacology

Volumn 165, Issue 8, 2012, Pages 2414-2424

  McHugh, Douglas ^a   Page, Jeremy ^a   Dunn, Emily ^a   Bradshaw, Heather B ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

Abnormal cannabidiol receptor; Cellular migration; Endometriosis; GPR18; NAGly; THC

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 2 METHYL 3 (1 NAPHTHOYL) 1 PROPYLINDOLE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; ANANDAMIDE; CANNABIDIOL; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; DRONABINOL; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 18; GLYCINE DERIVATIVE; METHANANDAMIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N ARACHIDONYL GLYCINE; PERTUSSIS TOXIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ASSAY; CELL LINE; CELL MIGRATION; CELL STIMULATION; CELL STRAIN HEC 1B; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENDOMETRIUM CELL; ENZYME ACTIVATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIPID ANALYSIS; MOLECULAR INTERACTION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; STABLE TRANSFECTION; TANDEM MASS SPECTROMETRY;

ARACHIDONIC ACIDS; CELL LINE, TUMOR; CELL MOVEMENT; ENDOMETRIUM; FEMALE; GLYCINE; HEK293 CELLS; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; TETRAHYDROCANNABINOL; TRANSFECTION;

EID: 84859046557     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01497.x     Document Type: Article

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