Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: An effect attenuated by phycocyanin

International Journal of Biochemistry and Cell Biology

Volumn 43, Issue 4, 2011, Pages 525-534

  Li, Xiao Ling ^a   Chen, Tianfeng ^b   Wong, Yum Shing ^b   Xu, Gang ^a   Fan, Rong Rong ^a   Zhao, Hai Lu ^a   Chan, Juliana C N ^a,b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Apoptosis; Human islet amyloid polypeptide; Mitochondria; Pancreatic beta cells; Phycocyanin

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMYLIN; APOPTOSIS INDUCING FACTOR; CASPASE; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHYCOCYANIN; PROTEIN BCL 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL MEMBRANE POTENTIAL; CELL PROTECTION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; FRAGMENTATION REACTION; INSULINOMA; MITOCHONDRION; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT;

ANIMALS; APOPTOSIS; APOPTOSIS INDUCING FACTOR; CASPASES; CELL LINE, TUMOR; CYTOCHROMES C; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; INSULIN-SECRETING CELLS; ISLET AMYLOID POLYPEPTIDE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MITOCHONDRIA; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHYCOCYANIN; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS;

RATTUS;

EID: 79952101635     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.12.008     Document Type: Article

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