Temporal and site-specific brain alterations in CB1 receptor binding in high fat diet-induced obesity in c57bl/6 mice

Journal of Neuroendocrinology

Volumn 20, Issue 11, 2008, Pages 1288-1294

  South, T ^a   Huang, Xu Feng ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

Autoradiography; C57Bl 6; Cannabinoid CB1 receptor; High fat diet; Obesity

Indexed keywords

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; CANNABINOID 1 RECEPTOR; CARBOHYDRATE; ENDOCANNABINOID; FAT; LEPTIN; LIGAND; TRITIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CARBOHYDRATE DIET; CONTROLLED STUDY; FEEDING; HISTOLOGY; HORMONE BLOOD LEVEL; HYPERPHAGIA; HYPOTHALAMUS; INSULA; LIPID DIET; MALE; MOUSE; NONHUMAN; OBESITY; OLFACTORY NUCLEUS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIOIMMUNOASSAY; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM;

ANIMALS; BODY WEIGHT; BRAIN; CANNABINOIDS; CYCLOHEXANOLS; DIET; DIETARY FATS; ENERGY INTAKE; HUMANS; LEPTIN; MALE; MICE; MICE, INBRED C57BL; OBESITY; RECEPTOR, CANNABINOID, CB1;

EID: 53949086484     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2008.01785.x     Document Type: Article

References (38)

1. Wilson RI, Nicoll RA. Endocannabinoid signaling in the brain. Science 2002; 296: 678-682.
2. Abel E. Cannabis: Effects on hunger and thirst. Behav Biol 1975; 15: 255-281.
3. Williams CM, Kirkham TC. Anandamide induces overeating: Mediation by central cannabinoid (CB1) receptors. Psychopharmacology 1999; 143: 315-317.
4. Arnone M, Maruani J, Chaperon F, Thiebot MH, Poncelet M, Soubrie P, Le Fur G. Selective inhibition of sucrose and ethanol intake by SR 141716, an antagonist of central cannabinoid (CB1) receptors. Psychopharmacology (Berl) 1997; 132: 104-106.
5. Ravinet Trillou C, Arnone M, Delgorge C, Gonalons N, Keane P, Maffrand J-P, Soubrie P. Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice. Am J Physiol Regul Integr Comp Physiol 2003; 284: R345-R353.
6. Mathes CM, Ferrara M, Rowland NE. Cannabinoid CB1 receptor antagonists reduce caloric intake by decreasing palatable diet selection in a novel dessert protocol in female rats. Am J Physiol Regul Integr Comp Physiol 2008; 295 (1): R67-75.
7. Matias I, Di Marzo V. Endocannabinoids and the control of energy balance. Trends Endocrinol Metab 2007; 18: 27-37.
8. Chambers AP, Sharkey KA, Koopmans HS. Cannabinoid (CB)1 receptor antagonist, AM 251, causes a sustained reduction of daily food intake in the rat. Physiol Behav 2004; 82: 863-869.
9. Di Marzo V, Matias I. Endocannabinoid control of food intake and energy balance. Nat Neurosci 2005; 8: 585-589.
10. Di Marzo V, Goparaju SK, Wang L, Liu J, Batkai S, Jarai Z, Fezza F, Miura GI, Palmiter RD, Sugiura T, Kunos G. Leptin-regulated endocannabinoids are involved in maintaining food intake. Nature 2001; 410: 822-825.
11. Bluher M, Engeli S, Kloting N, Berndt J, Fasshauer M, Batkai S, Pacher P, Schon MR, Jordan J, Stumvoll M. Dysregulation of the peripheral and adipose tissue endocannabinoid system in human abdominal obesity. Diabetes 2006; 55: 3053-3060.
12. Harrold JA, Elliott JC, King PJ, Widdowson PS, Williams G. Down-regulation of cannabinoid-1 (CB-1) receptors in specific extrahypothalamic regions of rats with dietary obesity: A role for endogenous cannabinoids in driving appetite for palatable food? Brain Res 2002; 952: 232-238.
13. Lin S, Thomas TC, Storlien LH, Huang XF. Development of high fat diet-induced obesity and leptin resistance in C57B1/6J mice. Int J Obes 2000; 24: 639-646.
14. Reeves PGNF, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993; 11: 1939-1951.
15. Paxinos G, Franklin KBJ. The Mouse Brain in Stereotaxic Coordinates. San Diego, CA: Academic Press, 2002.
16. Huang X-F, Yu Y, Zavitsanou K, Han M, Storlien L. Differential expression of dopamine D2 and D4 receptor and tyrosine hydroxylase mRNA in mice prone, or resistant, to chronic high-fat diet-induced obesity. Brain Res Mol Brain Res 2005; 135: 150-161.
17. Breivogel CS, Childers SR, Deadwyler SA, Hampson RE, Vogt LJ, Sim-Selley LJ. Chronic 9-tetrahydrocannabinol treatment produces a time-dependent loss of cannabinoid receptors and cannabinoid receptor-activated G proteins in rat brain. J Neurochem 1999; 73: 2447-2459.
18. Oviedo A, Glowa J, Herkenham M. Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: A quantitative autoradiographic study. Brain Res 1993; 616: 293-302.
19. Rubino T, Vigano D, Massi P, Parolaro D. Changes in the cannabinoid receptor binding, G protein coupling, and cyclic AMP cascade in the CNS of rats tolerant to and dependent on the synthetic cannabinoid compound CP55,940. J Neurochem 2000; 75: 2080-2086.
20. Rubino T, Patrini G, Parenti M, Massi P, Parolaro D. Chronic treatment with a synthetic cannabinoid CP-55,940 alters G-protein expression in the rat central nervous system. Brain Res Mol Brain Res 1997; 44: 191-197.
21. Hansson AC, Bermudez-Silva FJ, Malinen H, Hyytia P, Sanchez-Vera I, Rimondini R, Rodriguez de Fonseca F, Kunos G, Sommer WH, Heilig M. Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference. Neuropsychopharmacology 2006; 32: 117-126.
22. Sim-Selley LJ, Schechter NS, Rorrer WK, Dalton GD, Hernandez J, Martin BR, Selley DE. Prolonged recovery rate of CB1 receptor adaptation after cessation of long-term cannabinoid administration. Mol Pharmacol 2006; 70: 986-996.
23. Rubino T, Massi P, Patrini G, Venier I, Giagnoni G, Parolaro D. Chronic CP-55,940 alters cannabinoid receptor mRNA in the rat brain: An in situ hybridization study. Neuroreport 1994; 5: 2493-2496.
24. Pertwee RG. Pharmacology of cannabinoid receptor ligands. Curr Med Chem 1999; 6: 635-664.
25. Gong J-P, Onaivi ES, Ishiguro H, Liu Q-R, Tagliaferro PA, Brusco A, Uhl GR. Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain. Brain Res 2006; 1071: 10-23.
26. Griffin G, Wray EJ, Tao Q, McAllister SD, Rorrer WK, Aung M, Martin BR, Abood ME. Evaluation of the cannabinoid CB2 receptor-selective antagonist, SR144528: Further evidence for cannabinoid CB2 receptor absence in the rat central nervous system. Eur J Pharmacol 1999; 377: 117-125.
27. Jo Y-H, Chen Y-JJ, Chua JSC, Talmage DA, Role LW. Integration of endocannabinoid and leptin signaling in an appetite-related neural circuit. Neuron 2005; 48: 1055-1066.
28. Matias I, Petrosino S, Racioppi A, Capasso R, Izzo AA, Di Marzo V. Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets. Mol Cell Endocrinol. 2008; 286 (Suppl 1): S66-S78.
29. Huang XF, Han M, Storlien LH. The level of NPY receptor mRNA expression in diet-induced obese and resistant mice. Brain Res Mol Brain Res 2003; 115: 21-28.
30. Matias I, Vergoni AV, Petrosino S, Ottani A, Pocai A, Bertolini A, Di Marzo V. Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: insulin and melanocortins. Neuropharmacology 2008; 54: 206-212.
31. Sewards TV. Dual separate pathways for sensory and hedonic aspects of taste. Brain Res Bull 2004; 62: 271-283.
32. Rosell A, Gimenez Amaya JM. Considerations upon the anatomical model of reward-based learning in the basal ganglia. Med Hypotheses 2000; 54: 397-399.
33. Zangen A, Solinas M, Ikemoto S, Goldberg SR, Wise RA. Two brain sites for cannabinoid reward. J Neurosci 2006; 26: 4901-4907.
34. Gardner EL. Endocannabinoid signaling system and brain reward: Emphasis on dopamine. Pharmacol Biochem Behav 2005; 81: 263-284.
35. Ward SJ, Dykstra LA. The role of CB1 receptors in sweet versus fat reinforcement: Effect of CB1 receptor deletion, CB1 receptor antagonism (SR141716A) and CB1 receptor agonism (CP-55940). Behav Pharmacol 2005; 16: 381-388.
36. Ward SJ, Walker EA, Dykstra LA. Effect of cannabinoid CB1 receptor antagonist SR141714A and CB1 receptor knockout on cue-induced reinstatement of ensure[reg] and corn-oil seeking in mice. Neuropsychopharmacology 2007; 32: 2592-2600.
37. Berger A, Crozier G, Bisogno T, Cavaliere P, Innis S, Di Marzo V. Anandamide and diet: Inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N -acylethanolamines in piglets. Proc Natl Acad Sci USA 2001; 98: 6402-6406.
38. Artmann A, Petersen G, Hellgren LI, Boberg J, Skonberg C, Nellemann C, Hansen SH, Hansen HS. Influence of dietary fatty acids on endocannabinoid and N -acylethanolamine levels in rat brain, liver and small intestine. Biochim Biophys Acta 2008; 1781: 200-212.