High-fat diets cause insulin resistance despite an increase in muscle mitochondria

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 22, 2008, Pages 7815-7820

  Hancock, Chad R ^a   Han, Dong Ho ^a   Chen, May ^a   Terada, Shin ^a   Yasuda, Toshihiro ^a   Wright, David C ^a   Holloszy, John O ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Mitochondrial biogenesis; Mitochondrial dysfunction; PGC 1 ; PPAR ; Skeletal muscle

Indexed keywords

FATTY ACID DERIVATIVE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; FATTY ACID; PPARGC1A PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEEDING; INSULIN RESISTANCE; LIPID DIET; MALE; MOUSE; MUSCLE MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; ABDOMINAL FAT; ANIMAL; BLOOD; BODY WEIGHT; DIET; DRUG EFFECT; DRUG POTENTIATION; FAT INTAKE; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION; RAT; SKELETAL MUSCLE; ULTRASTRUCTURE; WISTAR RAT;

RATTUS;

ABDOMINAL FAT; ANIMALS; BODY WEIGHT; DIET; DIETARY FATS; FATTY ACIDS, NONESTERIFIED; INSULIN RESISTANCE; MALE; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; OXIDATION-REDUCTION; PPAR DELTA; RATS; RATS, WISTAR; TRANS-ACTIVATORS;

EID: 45549089279     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802057105     Document Type: Article

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