메뉴 건너뛰기




Volumn 7, Issue 4, 2012, Pages 856-865

The endocannabinoids anandamide and virodhamine modulate the activity of the candidate cannabinoid receptor GPR55

Author keywords

Anandamide; Endocannabinoids; GPCR; GPR55; Virodhamine

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; ANANDAMIDE; BETA ARRESTIN 2; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; CANNABINOID RECEPTOR; CANNABINOID RECEPTOR GPR55; GREEN FLUORESCENT PROTEIN; LACTATE DEHYDROGENASE; RIMONABANT; UNCLASSIFIED DRUG; VIRODHAMINE;

EID: 84875841356     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-012-9351-6     Document Type: Article
Times cited : (80)

References (36)
  • 1
    • 0035979606 scopus 로고    scopus 로고
    • Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity
    • 11514075 10.1016/S0304-3940(01)02065-1 1:CAS:528:DC%2BD3MXmtFWis78%3D
    • Abood ME, Rizvi G, Sallapudi N, McAllister SD (2001) Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity. Neurosci Lett 309(3):197-201
    • (2001) Neurosci Lett , vol.309 , Issue.3 , pp. 197-201
    • Abood, M.E.1    Rizvi, G.2    Sallapudi, N.3    McAllister, S.D.4
  • 2
    • 84855272776 scopus 로고    scopus 로고
    • Modulation of L-alpha-Lysophosphatidylinositol/GPR55 Mitogen-activated Protein Kinase (MAPK) Signaling by Cannabinoids
    • 10.1074/jbc.M111.296020 22027819 10.1074/jbc.M111.296020 1:CAS:528:DC%2BC38XotVKq
    • Anavi-Goffer S, Baillie G, Irving AJ, Gertsch J, Greig IR, Pertwee RG, Ross RA (2012) Modulation of L-alpha-Lysophosphatidylinositol/GPR55 Mitogen-activated Protein Kinase (MAPK) Signaling by Cannabinoids. J Biol Chem 287(1):91-104. doi: 10.1074/jbc.M111.296020
    • (2012) J Biol Chem , vol.287 , Issue.1 , pp. 91-104
    • Anavi-Goffer, S.1    Baillie, G.2    Irving, A.J.3    Gertsch, J.4    Greig, I.R.5    Pertwee, R.G.6    Ross, R.A.7
  • 3
    • 78651393400 scopus 로고    scopus 로고
    • The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK
    • 10.1038/onc.2010.402 20818416 10.1038/onc.2010.402 1:CAS:528: DC%2BC3cXhtFWksr3F
    • Andradas C, Caffarel MM, Perez-Gomez E, Salazar M, Lorente M, Velasco G, Guzman M, Sanchez C (2011) The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK. Oncogene 30(2):245-252. doi: 10.1038/onc.2010.402
    • (2011) Oncogene , vol.30 , Issue.2 , pp. 245-252
    • Andradas, C.1    Caffarel, M.M.2    Perez-Gomez, E.3    Salazar, M.4    Lorente, M.5    Velasco, G.6    Guzman, M.7    Sanchez, C.8
  • 5
    • 78751650607 scopus 로고    scopus 로고
    • The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca2+ -activated large-conductance K + channels in endothelial cells
    • 10.1007/s00424-010-0898-x 21072666 10.1007/s00424-010-0898-x 1:CAS:528:DC%2BC3MXjsVGn
    • Bondarenko AI, Malli R, Graier WF (2011) The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca2+ -activated large-conductance K + channels in endothelial cells. Pflugers Arch 461(1):177-189. doi: 10.1007/s00424-010-0898-x
    • (2011) Pflugers Arch , vol.461 , Issue.1 , pp. 177-189
    • Bondarenko, A.I.1    Malli, R.2    Graier, W.F.3
  • 6
    • 0029153913 scopus 로고
    • Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
    • 7638161 10.1073/pnas.92.16.7162 1:CAS:528:DyaK2MXntlKmsLY%3D
    • Bonfoco E, Krainc D, Ankarcrona M, Nicotera P, Lipton SA (1995) Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci U S A 92(16):7162-7166
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.16 , pp. 7162-7166
    • Bonfoco, E.1    Krainc, D.2    Ankarcrona, M.3    Nicotera, P.4    Lipton, S.A.5
  • 8
    • 0032401036 scopus 로고    scopus 로고
    • Endocannabinoids: Endogenous cannabinoid receptor ligands with neuromodulatory action
    • 9881850 10.1016/S0166-2236(98)01283-1
    • Di Marzo V, Melck D, Bisogno T, De Petrocellis L (1998) Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action. Trends Neurosci 21(12):521-528
    • (1998) Trends Neurosci , vol.21 , Issue.12 , pp. 521-528
    • Di Marzo, V.1    Melck, D.2    Bisogno, T.3    De Petrocellis, L.4
  • 9
    • 77952627758 scopus 로고    scopus 로고
    • A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells
    • 10.1111/j.1476-5381.2010.00743.x 20590578 10.1111/j.1476-5381.2010.00743. x 1:CAS:528:DC%2BC3cXpslyqsrY%3D
    • Ford LA, Roelofs AJ, Anavi-Goffer S, Mowat L, Simpson DG, Irving AJ, Rogers MJ, Rajnicek AM, Ross RA (2010) A role for L-alpha- lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells. Br J Pharmacol 160(3):762-771. doi: 10.1111/j.1476-5381.2010.00743.x
    • (2010) Br J Pharmacol , vol.160 , Issue.3 , pp. 762-771
    • Ford, L.A.1    Roelofs, A.J.2    Anavi-Goffer, S.3    Mowat, L.4    Simpson, D.G.5    Irving, A.J.6    Rogers, M.J.7    Rajnicek, A.M.8    Ross, R.A.9
  • 10
    • 79959333069 scopus 로고    scopus 로고
    • Cannabinoid receptor 2 undergoes Rab5-mediated internalization and recycles via a Rab11-dependent pathway
    • 10.1016/j.bbamcr.2011.05.010 21640764 10.1016/j.bbamcr.2011.05.010 1:CAS:528:DC%2BC3MXotVelurk%3D
    • Grimsey NL, Goodfellow CE, Dragunow M, Glass M (2011) Cannabinoid receptor 2 undergoes Rab5-mediated internalization and recycles via a Rab11-dependent pathway. Biochim Biophys Acta 1813(8):1554-1560. doi: 10.1016/j.bbamcr.2011.05.010
    • (2011) Biochim Biophys Acta , vol.1813 , Issue.8 , pp. 1554-1560
    • Grimsey, N.L.1    Goodfellow, C.E.2    Dragunow, M.3    Glass, M.4
  • 11
    • 58249109364 scopus 로고    scopus 로고
    • The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation
    • 10.1096/fj.08-108670 18757503 10.1096/fj.08-108670 1:CAS:528: DC%2BD1MXlsVOltQ%3D%3D
    • Henstridge CM, Balenga NA, Ford LA, Ross RA, Waldhoer M, Irving AJ (2009) The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation. FASEB J 23(1):183-193. doi: 10.1096/fj.08-108670
    • (2009) FASEB J , vol.23 , Issue.1 , pp. 183-193
    • Henstridge, C.M.1    Balenga, N.A.2    Ford, L.A.3    Ross, R.A.4    Waldhoer, M.5    Irving, A.J.6
  • 14
    • 79959724636 scopus 로고    scopus 로고
    • Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor
    • 10.1038/labinvest.2011.62 21464819 10.1038/labinvest.2011.62 1:CAS:528:DC%2BC3MXotlCjsL8%3D
    • Huang L, Ramirez JC, Frampton GA, Golden LE, Quinn MA, Pae HY, Horvat D, Liang LJ, DeMorrow S (2011) Anandamide exerts its antiproliferative actions on cholangiocarcinoma by activation of the GPR55 receptor. Lab Invest 91(7):1007-1017. doi: 10.1038/labinvest.2011.62
    • (2011) Lab Invest , vol.91 , Issue.7 , pp. 1007-1017
    • Huang, L.1    Ramirez, J.C.2    Frampton, G.A.3    Golden, L.E.4    Quinn, M.A.5    Pae, H.Y.6    Horvat, D.7    Liang, L.J.8    Demorrow, S.9
  • 15
    • 80053649319 scopus 로고    scopus 로고
    • New blood brothers: The GPR55 and CB(2) partnership
    • doi: 10.1038/cr.2011.77
    • Irving A (2011) New blood brothers: the GPR55 and CB(2) partnership. Cell Res. doi: 10.1038/cr.2011.77
    • (2011) Cell Res
    • Irving, A.1
  • 16
    • 3242724820 scopus 로고    scopus 로고
    • Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes
    • 10.1007/s00262-004-0509-9 [doi] 15034673 10.1007/s00262-004-0509-9 1:CAS:528:DC%2BD2cXltF2hsrg%3D
    • Joseph J, Niggemann B, Zaenker KS, Entschladen F (2004) Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. Cancer Immunol Immunother 53(8):723-728. doi: 10.1007/s00262-004-0509-9 [doi]
    • (2004) Cancer Immunol Immunother , vol.53 , Issue.8 , pp. 723-728
    • Joseph, J.1    Niggemann, B.2    Zaenker, K.S.3    Entschladen, F.4
  • 17
    • 70350376735 scopus 로고    scopus 로고
    • Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands
    • 10.1074/jbc.M109.050187 19723626 10.1074/jbc.M109.050187 1:CAS:528:DC%2BD1MXht1KqurnM
    • Kapur A, Zhao P, Sharir H, Bai Y, Caron MG, Barak LS, Abood ME (2009) Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands. J Biol Chem 284(43):29817-29827. doi: 10.1074/jbc.M109.050187
    • (2009) J Biol Chem , vol.284 , Issue.43 , pp. 29817-29827
    • Kapur, A.1    Zhao, P.2    Sharir, H.3    Bai, Y.4    Caron, M.G.5    Barak, L.S.6    Abood, M.E.7
  • 19
    • 40649102938 scopus 로고    scopus 로고
    • GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current
    • 10.1073/pnas.0711278105 18263732 10.1073/pnas.0711278105 1:CAS:528:DC%2BD1cXis1yisr0%3D
    • Lauckner JE, Jensen JB, Chen HY, Lu HC, Hille B, Mackie K (2008) GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current. Proc Natl Acad Sci U S A 105(7):2699-2704. doi: 10.1073/pnas.0711278105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.7 , pp. 2699-2704
    • Lauckner, J.E.1    Jensen, J.B.2    Chen, H.Y.3    Lu, H.C.4    Hille, B.5    Mackie, K.6
  • 21
    • 34548591720 scopus 로고    scopus 로고
    • Identification of GPR55 as a lysophosphatidylinositol receptor
    • 10.1016/j.bbrc.2007.08.078 17765871 10.1016/j.bbrc.2007.08.078 1:CAS:528:DC%2BD2sXhtVGitr%2FP
    • Oka S, Nakajima K, Yamashita A, Kishimoto S, Sugiura T (2007) Identification of GPR55 as a lysophosphatidylinositol receptor. Biochem Biophys Res Commun 362(4):928-934. doi: 10.1016/j.bbrc.2007.08.078
    • (2007) Biochem Biophys Res Commun , vol.362 , Issue.4 , pp. 928-934
    • Oka, S.1    Nakajima, K.2    Yamashita, A.3    Kishimoto, S.4    Sugiura, T.5
  • 24
    • 67349196005 scopus 로고    scopus 로고
    • Differential changes in GPR55 during microglial cell activation
    • 10.1016/j.febslet.2009.05.028 19464294 10.1016/j.febslet.2009.05.028 1:CAS:528:DC%2BD1MXnt1Okurk%3D
    • Pietr M, Kozela E, Levy R, Rimmerman N, Lin YH, Stella N, Vogel Z, Juknat A (2009) Differential changes in GPR55 during microglial cell activation. FEBS Lett 583(12):2071-2076. doi: 10.1016/j.febslet.2009.05.028
    • (2009) FEBS Lett , vol.583 , Issue.12 , pp. 2071-2076
    • Pietr, M.1    Kozela, E.2    Levy, R.3    Rimmerman, N.4    Lin, Y.H.5    Stella, N.6    Vogel, Z.7    Juknat, A.8
  • 25
    • 78651383853 scopus 로고    scopus 로고
    • The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation
    • 10.1038/onc.2010.417 20838378 10.1038/onc.2010.417 1:CAS:528: DC%2BC3cXhtFGgtrzE
    • Pineiro R, Maffucci T, Falasca M (2011) The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation. Oncogene 30(2):142-152. doi: 10.1038/onc.2010.417
    • (2011) Oncogene , vol.30 , Issue.2 , pp. 142-152
    • Pineiro, R.1    Maffucci, T.2    Falasca, M.3
  • 28
    • 77952651099 scopus 로고    scopus 로고
    • The endocannabinoid system as a target for the treatment of neurodegenerative disease
    • Scotter EL, Abood ME, Glass M (2010) The endocannabinoid system as a target for the treatment of neurodegenerative disease. Br J Pharmacol 160:480-498
    • (2010) Br J Pharmacol , vol.160 , pp. 480-498
    • Scotter, E.L.1    Abood, M.E.2    Glass, M.3
  • 29
    • 0030425575 scopus 로고    scopus 로고
    • Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands
    • 8819477 1:CAS:528:DyaK28XmtVSjs74%3D
    • Showalter VM, Compton DR, Martin BR, Abood ME (1996) Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands. J Pharmacol Exp Ther 278(3):989-999
    • (1996) J Pharmacol Exp Ther , vol.278 , Issue.3 , pp. 989-999
    • Showalter, V.M.1    Compton, D.R.2    Martin, B.R.3    Abood, M.E.4
  • 31
    • 0033653297 scopus 로고    scopus 로고
    • 2-Arachidonoylglycerol and the cannabinoid receptors
    • Sugiura T, Waku K (2000) 2-Arachidonoylglycerol and the cannabinoid receptors. Chem Phys Lipids 108:89-106
    • (2000) Chem Phys Lipids , vol.108 , pp. 89-106
    • Sugiura, T.1    Waku, K.2
  • 32
    • 0031808129 scopus 로고    scopus 로고
    • 2, disrupts G-protein coupling
    • 9580609 1:CAS:528:DyaK1cXjtF2gu7w%3D
    • 2, disrupts G-protein coupling. J Pharmacol Exp Ther 285(2):651-658
    • (1998) J Pharmacol Exp Ther , vol.285 , Issue.2 , pp. 651-658
    • Tao, Q.1    Abood, M.E.2
  • 33
    • 65449156031 scopus 로고    scopus 로고
    • Beta-arrestin-based Bret2 screening assay for the "non"-beta- arrestin binding CB1 receptor
    • 10.1177/1087057109333101 19403920 10.1177/1087057109333101 1:CAS:528:DC%2BD1MXltFygu70%3D
    • Vrecl M, Norregaard PK, Almholt DL, Elster L, Pogacnik A, Heding A (2009) Beta-arrestin-based Bret2 screening assay for the "non"-beta-arrestin binding CB1 receptor. J Biomol Screen 14(4):371-380. doi: 10.1177/ 1087057109333101
    • (2009) J Biomol Screen , vol.14 , Issue.4 , pp. 371-380
    • Vrecl, M.1    Norregaard, P.K.2    Almholt, D.L.3    Elster, L.4    Pogacnik, A.5    Heding, A.6
  • 34
    • 1842611884 scopus 로고    scopus 로고
    • Cannabinoids and neuroinflammation
    • 10.1038/sj.bjp.0705667 14757702 10.1038/sj.bjp.0705667 1:CAS:528:DC%2BD2cXivFCgsLk%3D
    • Walter L, Stella N (2004) Cannabinoids and neuroinflammation. Br J Pharmacol 141(5):775-785. doi: 10.1038/sj.bjp.0705667
    • (2004) Br J Pharmacol , vol.141 , Issue.5 , pp. 775-785
    • Walter, L.1    Stella, N.2
  • 35
    • 70349510641 scopus 로고    scopus 로고
    • The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo
    • 10.1073/pnas.0902743106 19805329 10.1073/pnas.0902743106 1:CAS:528:DC%2BD1MXht1Kqtb7E
    • Whyte LS, Ryberg E, Sims NA, Ridge SA, Mackie K, Greasley PJ, Ross RA, Rogers MJ (2009) The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo. Proc Natl Acad Sci U S A 106(38):16511-16516. doi: 10.1073/pnas.0902743106
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.38 , pp. 16511-16516
    • Whyte, L.S.1    Ryberg, E.2    Sims, N.A.3    Ridge, S.A.4    Mackie, K.5    Greasley, P.J.6    Ross, R.A.7    Rogers, M.J.8
  • 36
    • 66449121455 scopus 로고    scopus 로고
    • Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay
    • 10.1074/jbc.M806516200 19286662 10.1074/jbc.M806516200 1:CAS:528:DC%2BD1MXltVClsrw%3D
    • Yin H, Chu A, Li W, Wang B, Shelton F, Otero F, Nguyen DG, Caldwell JS, Chen YA (2009) Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay. J Biol Chem 284(18):12328-12338. doi: 10.1074/jbc.M806516200
    • (2009) J Biol Chem , vol.284 , Issue.18 , pp. 12328-12338
    • Yin, H.1    Chu, A.2    Li, W.3    Wang, B.4    Shelton, F.5    Otero, F.6    Nguyen, D.G.7    Caldwell, J.S.8    Chen, Y.A.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.