Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

Journal of Clinical Investigation

Volumn 115, Issue 5, 2005, Pages 1298-1305

  Osei Hyiaman, Douglas ^a   DePetrillo, Michael ^a   Pacher, Pál ^a   Liu, Jie ^a   Radaeva, Svetlana ^a   Bátkai, Sándor ^a   Harvey White, Judith ^a   Mackie, Ken ^b   Offertáler, László ^a   Wang, Lei ^a   Kunos, George ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR AGONIST; FATTY ACID; FATTY ACID SYNTHASE; FATTY ACID SYNTHASE INHIBITOR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANOREXIA; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DRUG ACTIVATION; ENZYME ACTIVATION; FATTY ACID SYNTHESIS; GENE EXPRESSION; HYPOTHALAMUS; LIPID DIET; LIPOGENESIS; LIVER; LIVER CELL; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN TARGETING;

ANIMALS; ARACHIDONIC ACIDS; CCAAT-ENHANCER-BINDING PROTEINS; DIET; DIETARY FATS; DNA-BINDING PROTEINS; ENDOCANNABINOIDS; FATTY ACIDS; FATTY LIVER; HYPOTHALAMUS; LIVER; MICE; OBESITY; POLYUNSATURATED ALKAMIDES; RECEPTOR, CANNABINOID, CB1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTORS;

EID: 20944436157     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200523057     Document Type: Article

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