Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA)

Biochemical and Biophysical Research Communications

Volumn 430, Issue 2, 2013, Pages 573-578

  Hagland, Hanne R ^a   Nilsson, Linn I H ^a   Burri, Lena ^a   Nikolaisen, Julie ^a   Berge, Rolf K ^a,b   Tronstad, Karl J ^a  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

Author keywords

Hypertrophy; Mitochondrial biogenesis; Mitochondrial respiration; MTOR; PPAR; Rat hepatocytes

Indexed keywords

CITRATE SYNTHASE; INITIATION FACTOR 4E BINDING PROTEIN 1; INITIATION FACTOR 4G; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MITOCHONDRIAL DNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TETRADECYLTHIOACETIC ACID; THIOACETIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOGENESIS; CELL FUNCTION; CELL STRUCTURE; ELECTRON TRANSPORT; ENZYME ACTIVATION; GENETIC ANALYSIS; LIVER CELL; LIVER HYPERTROPHY; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL ENLARGEMENT; CELLS, CULTURED; HEPATOCYTES; HYPOLIPIDEMIC AGENTS; MALE; MITOCHONDRIA, LIVER; MITOCHONDRIAL TURNOVER; OXIDATION-REDUCTION; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; RATS; RATS, WISTAR; SULFIDES; TOR SERINE-THREONINE KINASES;

MAMMALIA; RATTUS;

EID: 84872332700     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.11.111     Document Type: Article

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