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Volumn 18, Issue 12, 2013, Pages 1526-1535

The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation

Author keywords

Anandamide; Apoptosis; Decidual cells

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; ANANDAMIDE; CANNABINOID 1 RECEPTOR; CASPASE 3; CASPASE 7; CERAMIDE; CYCLOSERINE; FUMONISIN B1; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE;

EID: 84889101230     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0892-9     Document Type: Article
Times cited : (47)

References (35)
  • 1
    • 84877081113 scopus 로고    scopus 로고
    • Endogenous cannabinoids revisited: A biochemistry perspective
    • 10.1016/j.prostaglandins.2013.02.002 23474290 10.1016/j.prostaglandins. 2013.02.002 1:CAS:528:DC%2BC3sXkt12qurk%3D
    • Fonseca BM, Costa MA, Almada M, Correia-da-Silva G, Teixeira NA (2013) Endogenous cannabinoids revisited: a biochemistry perspective. Prostaglandins Other Lipid Mediat 102-103:13-30. doi: 10.1016/j.prostaglandins.2013.02.002
    • (2013) Prostaglandins Other Lipid Mediat , vol.102-103 , pp. 13-30
    • Fonseca, B.M.1    Costa, M.A.2    Almada, M.3    Correia-Da-Silva, G.4    Teixeira, N.A.5
  • 2
    • 0028970517 scopus 로고
    • 2-Arachidonoylglycerol: A possible endogenous cannabinoid receptor ligand in brain
    • 7575630 10.1006/bbrc.1995.2437 1:CAS:528:DyaK2MXosVyqtLk%3D
    • Sugiura T, Kondo S, Sukagawa A, Nakane S, Shinoda A, Itoh K et al (1995) 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. Biochem Biophys Res Commun 215:89-97
    • (1995) Biochem Biophys Res Commun , vol.215 , pp. 89-97
    • Sugiura, T.1    Kondo, S.2    Sukagawa, A.3    Nakane, S.4    Shinoda, A.5    Itoh, K.6
  • 3
    • 0027078685 scopus 로고
    • Isolation and structure of a brain constituent that binds to the cannabinoid receptor
    • 1470919 10.1126/science.1470919 1:CAS:528:DyaK3sXpvVKntg%3D%3D
    • Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G et al (1992) Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 258:1946-1949
    • (1992) Science , vol.258 , pp. 1946-1949
    • Devane, W.A.1    Hanus, L.2    Breuer, A.3    Pertwee, R.G.4    Stevenson, L.A.5    Griffin, G.6
  • 4
    • 52949149368 scopus 로고    scopus 로고
    • The tools of the trade" - An overview of the pharmacology of the endocannabinoid system
    • 18781976 10.2174/138161208785740126 1:CAS:528:DC%2BD1cXht1SgtbnP
    • Fowler CJ (2008) "The tools of the trade" - an overview of the pharmacology of the endocannabinoid system. Curr Pharm Des 14:2254-2265
    • (2008) Curr Pharm des , vol.14 , pp. 2254-2265
    • Fowler, C.J.1
  • 5
    • 75749126604 scopus 로고    scopus 로고
    • Signal transduction of the CB1 cannabinoid receptor
    • 19620237 10.1677/JME-08-0190 1:CAS:528:DC%2BC3cXhvFSitr0%3D
    • Turu G, Hunyady L (2010) Signal transduction of the CB1 cannabinoid receptor. J Mol Endocrinol 44:75-85
    • (2010) J Mol Endocrinol , vol.44 , pp. 75-85
    • Turu, G.1    Hunyady, L.2
  • 6
    • 0037380894 scopus 로고    scopus 로고
    • ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death
    • 12641726 10.1046/j.1471-4159.2003.01663.x 1:CAS:528:DC%2BD3sXislOltb4%3D
    • Sarker KP, Biswas KK, Yamakuchi M, Lee KY, Hahiguchi T, Kracht M et al (2003) ASK1-p38 MAPK/JNK signaling cascade mediates anandamide-induced PC12 cell death. J Neurochem 85:50-61
    • (2003) J Neurochem , vol.85 , pp. 50-61
    • Sarker, K.P.1    Biswas, K.K.2    Yamakuchi, M.3    Lee, K.Y.4    Hahiguchi, T.5    Kracht, M.6
  • 7
    • 0033081066 scopus 로고    scopus 로고
    • Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry
    • 9927426 10.1093/emboj/18.3.664 1:CAS:528:DyaK1MXhslais7k%3D
    • Brunet A, Roux D, Lenormand P, Dowd S, Keyse S, Pouyssegur J (1999) Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. EMBO J 18:664-674
    • (1999) EMBO J , vol.18 , pp. 664-674
    • Brunet, A.1    Roux, D.2    Lenormand, P.3    Dowd, S.4    Keyse, S.5    Pouyssegur, J.6
  • 8
    • 33751198532 scopus 로고    scopus 로고
    • Cannabinoid receptor-mediated apoptosis induced by R(+)-methanandamide and Win, 55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell lymphoma
    • 16936228 10.1124/mol.106.025981 1:CAS:528:DC%2BD28XhtFygsbnF
    • Gustafsson K, Christensson B, Sander B, Flygare J (2006) Cannabinoid receptor-mediated apoptosis induced by R(+)-methanandamide and Win, 55,212-2 is associated with ceramide accumulation and p38 activation in mantle cell lymphoma. Mol Pharmacol 70:1612-1620
    • (2006) Mol Pharmacol , vol.70 , pp. 1612-1620
    • Gustafsson, K.1    Christensson, B.2    Sander, B.3    Flygare, J.4
  • 9
    • 0036534724 scopus 로고    scopus 로고
    • De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis
    • 11903061 10.1042/0264-6021:3630183 1:CAS:528:DC%2BD38Xjt1aksLg%3D
    • Gomez del Pulgar T, Velasco G, Sanchez C, Haro A, Guzman M (2002) De novo-synthesized ceramide is involved in cannabinoid-induced apoptosis. Biochem J 363:183-188
    • (2002) Biochem J , vol.363 , pp. 183-188
    • Gomez Del Pulgar, T.1    Velasco, G.2    Sanchez, C.3    Haro, A.4    Guzman, M.5
  • 10
    • 0026773819 scopus 로고
    • Modulation of cell growth and differentiation by ceramide
    • 1644175 10.1016/0014-5793(92)80769-D 1:CAS:528:DyaK38XlsVyjtr0%3D
    • Bielawska A, Linardic CM, Hannun YA (1992) Modulation of cell growth and differentiation by ceramide. FEBS lett 307:211-214
    • (1992) FEBS Lett , vol.307 , pp. 211-214
    • Bielawska, A.1    Linardic, C.M.2    Hannun, Y.A.3
  • 11
    • 84870718175 scopus 로고    scopus 로고
    • Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism
    • 23226203 10.1371/journal.pone.0048571 1:CAS:528:DC%2BC38XhvVKqsbrI
    • Rego A, Costa M, Chaves SR, Matmati N, Pereira H, Sousa MJ et al (2012) Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism. PLoS One 7:e48571
    • (2012) PLoS One , vol.7 , pp. 48571
    • Rego, A.1    Costa, M.2    Chaves, S.R.3    Matmati, N.4    Pereira, H.5    Sousa, M.J.6
  • 12
    • 1842330849 scopus 로고    scopus 로고
    • Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione
    • 9111045 10.1074/jbc.272.17.11369 1:CAS:528:DyaK2sXjtVamuro%3D
    • Garcia-Ruiz C, Colell A, Mari M, Morales A, Fernandez-Checa JC (1997) Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J biol chem 272:11369-11377
    • (1997) J Biol Chem , vol.272 , pp. 11369-11377
    • Garcia-Ruiz, C.1    Colell, A.2    Mari, M.3    Morales, A.4    Fernandez-Checa, J.C.5
  • 13
    • 0041411118 scopus 로고    scopus 로고
    • The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis
    • 12934069 10.1038/sj.cdd.4401284 1:CAS:528:DC%2BD3sXmsFeisro%3D
    • Maccarrone M, Finazzi-Agro A (2003) The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis. Cell Death Differ 10:946-955
    • (2003) Cell Death Differ , vol.10 , pp. 946-955
    • Maccarrone, M.1    Finazzi-Agro, A.2
  • 14
    • 67349195495 scopus 로고    scopus 로고
    • Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines
    • 19394652 10.1016/j.jss.2008.06.045 1:CAS:528:DC%2BD1MXnsFSjsbg%3D
    • Miyato H, Kitayama J, Yamashita H, Souma D, Asakage M, Yamada J et al (2009) Pharmacological synergism between cannabinoids and paclitaxel in gastric cancer cell lines. J Surg Res 155:40-47
    • (2009) J Surg Res , vol.155 , pp. 40-47
    • Miyato, H.1    Kitayama, J.2    Yamashita, H.3    Souma, D.4    Asakage, M.5    Yamada, J.6
  • 15
    • 71149083322 scopus 로고    scopus 로고
    • Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: Evidence for a role of the endocannabinoid system during the period of placental development
    • 19860893 10.1186/1477-7827-7-121
    • Fonseca BM, Correia-da-Silva G, Taylor AH, Konje JC, Bell SC, Teixeira NA (2009) Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development. Reprod Biol Endocrinol 7:121
    • (2009) Reprod Biol Endocrinol , vol.7 , pp. 121
    • Fonseca, B.M.1    Correia-Da-Silva, G.2    Taylor, A.H.3    Konje, J.C.4    Bell, S.C.5    Teixeira, N.A.6
  • 17
    • 79954495409 scopus 로고    scopus 로고
    • The role of sex steroid hormones, cytokines and the endocannabinoid system in female fertility
    • 21227997 10.1093/humupd/dmq058 1:CAS:528:DC%2BC3MXksFKnu7Y%3D
    • Karasu T, Marczylo TH, Maccarrone M, Konje JC (2011) The role of sex steroid hormones, cytokines and the endocannabinoid system in female fertility. Hum Reprod Update 17:347-361
    • (2011) Hum Reprod Update , vol.17 , pp. 347-361
    • Karasu, T.1    Marczylo, T.H.2    Maccarrone, M.3    Konje, J.C.4
  • 18
    • 77954927264 scopus 로고    scopus 로고
    • N-acylethanolamine levels and expression of their metabolizing enzymes during pregnancy
    • 20534733 10.1210/en.2009-1424 1:CAS:528:DC%2BC3cXht1Oju73P
    • Fonseca BM, Correia-da-Silva G, Taylor AH, Lam PM, Marczylo TH, Konje JC et al (2010) N-acylethanolamine levels and expression of their metabolizing enzymes during pregnancy. Endocrinology 151:3965-3974
    • (2010) Endocrinology , vol.151 , pp. 3965-3974
    • Fonseca, B.M.1    Correia-Da-Silva, G.2    Taylor, A.H.3    Lam, P.M.4    Marczylo, T.H.5    Konje, J.C.6
  • 19
    • 67650973436 scopus 로고    scopus 로고
    • Anandamide-induced cell death: Dual effects in primary rat decidual cell cultures
    • 19560819 10.1016/j.placenta.2009.05.012 1:CAS:528:DC%2BD1MXptVSitL4%3D
    • Fonseca BM, Correia-da-Silva G, Teixeira NA (2009) Anandamide-induced cell death: dual effects in primary rat decidual cell cultures. Placenta 30:686-692
    • (2009) Placenta , vol.30 , pp. 686-692
    • Fonseca, B.M.1    Correia-Da-Silva, G.2    Teixeira, N.A.3
  • 20
    • 33746271951 scopus 로고    scopus 로고
    • Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry
    • 16828308 10.1016/j.ymeth.2006.05.004 1:CAS:528:DC%2BD28XnsFymsbs%3D
    • Bielawski J, Szulc ZM, Hannun YA, Bielawska A (2006) Simultaneous quantitative analysis of bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. Methods 39:82-91
    • (2006) Methods , vol.39 , pp. 82-91
    • Bielawski, J.1    Szulc, Z.M.2    Hannun, Y.A.3    Bielawska, A.4
  • 22
    • 33748746334 scopus 로고    scopus 로고
    • When do lasses (longevity assurance genes) become CerS (ceramide synthases)? Insights into the regulation of ceramide synthesis
    • 16793762 10.1074/jbc.R600010200 1:CAS:528:DC%2BD28XoslKmurg%3D
    • Pewzner-Jung Y, Ben-Dor S, Futerman AH (2006) When do lasses (longevity assurance genes) become CerS (ceramide synthases)? Insights into the regulation of ceramide synthesis. J Biol Chem 281:25001-25005
    • (2006) J Biol Chem , vol.281 , pp. 25001-25005
    • Pewzner-Jung, Y.1    Ben-Dor, S.2    Futerman, A.H.3
  • 23
    • 9544246860 scopus 로고    scopus 로고
    • Mitochondrial permeability transition is a central coordinating event of apoptosis
    • 9064332 10.1084/jem.184.3.1155 1:CAS:528:DyaK28XlsFartLY%3D
    • Marchetti P, Castedo M, Susin SA, Zamzami N, Hirsch T, Macho A et al (1996) Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med 184:1155-1160
    • (1996) J Exp Med , vol.184 , pp. 1155-1160
    • Marchetti, P.1    Castedo, M.2    Susin, S.A.3    Zamzami, N.4    Hirsch, T.5    Macho, A.6
  • 24
    • 23044517184 scopus 로고    scopus 로고
    • Cannabinoids and ceramide: Two lipids acting hand-by-hand
    • 15958274 10.1016/j.lfs.2005.05.015 1:CAS:528:DC%2BD2MXmvVGitLw%3D
    • Velasco G, Galve-Roperh I, Sanchez C, Blazquez C, Haro A, Guzman M (2005) Cannabinoids and ceramide: two lipids acting hand-by-hand. Life Sci 77:1723-1731
    • (2005) Life Sci , vol.77 , pp. 1723-1731
    • Velasco, G.1    Galve-Roperh, I.2    Sanchez, C.3    Blazquez, C.4    Haro, A.5    Guzman, M.6
  • 25
    • 0027527545 scopus 로고
    • Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide
    • 8253743 1:CAS:528:DyaK3sXmsVKmu7k%3D
    • Bielawska A, Crane HM, Liotta D, Obeid LM, Hannun YA (1993) Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide. J biol chem 268:26226-26232
    • (1993) J Biol Chem , vol.268 , pp. 26226-26232
    • Bielawska, A.1    Crane, H.M.2    Liotta, D.3    Obeid, L.M.4    Hannun, Y.A.5
  • 26
    • 77952604846 scopus 로고    scopus 로고
    • Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells
    • 10.1111/j.1476-5381.2010.00712.x
    • Mohanraj R, Mukhopadhyay P, Hasko G, Liaudet L, Mackie K, Pacher P (2010) Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells. Br J Pharmacol 160(3):688-700
    • (2010) Br J Pharmacol , vol.160 , Issue.3 , pp. 688-700
    • Mohanraj, R.1    Mukhopadhyay, P.2    Hasko, G.3    Liaudet, L.4    Mackie, K.5    Pacher, P.6
  • 27
    • 77957270502 scopus 로고    scopus 로고
    • The endocannabinoid 2-arachidonoylglycerol (2-AG) and metabolizing enzymes during rat fetoplacental development: A role in uterine remodelling
    • 20727980 10.1016/j.biocel.2010.08.006 1:CAS:528:DC%2BC3cXht1ClsrnI
    • Fonseca BM, Correia-da-Silva G, Taylor AH, Lam PM, Marczylo TH, Bell SC et al (2010) The endocannabinoid 2-arachidonoylglycerol (2-AG) and metabolizing enzymes during rat fetoplacental development: a role in uterine remodelling. Int J Biochem Cell Biol 42:1884-1892
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1884-1892
    • Fonseca, B.M.1    Correia-Da-Silva, G.2    Taylor, A.H.3    Lam, P.M.4    Marczylo, T.H.5    Bell, S.C.6
  • 28
    • 77957747104 scopus 로고    scopus 로고
    • Cannabinoid receptor 1 mediates palmitic acid-induced apoptosis via endoplasmic reticulum stress in human renal proximal tubular cells
    • 20506110 10.1002/jcp.22255 1:CAS:528:DC%2BC3cXhtFGqsL7M
    • Lim JC, Lim SK, Han HJ, Park SH (2010) Cannabinoid receptor 1 mediates palmitic acid-induced apoptosis via endoplasmic reticulum stress in human renal proximal tubular cells. J Cell Physiol 225:654-663
    • (2010) J Cell Physiol , vol.225 , pp. 654-663
    • Lim, J.C.1    Lim, S.K.2    Han, H.J.3    Park, S.H.4
  • 29
    • 0037762572 scopus 로고    scopus 로고
    • The fate and function of glycosphingolipid glucosylceramide
    • 12803919 10.1098/rstb.2003.1266
    • van Meer G, Wolthoorn J, Degroote S (2003) The fate and function of glycosphingolipid glucosylceramide. Philos Trans R Soc Lond B Biol Sci 358:869-873
    • (2003) Philos Trans R Soc Lond B Biol Sci , vol.358 , pp. 869-873
    • Van Meer, G.1    Wolthoorn, J.2    Degroote, S.3
  • 30
    • 84871796893 scopus 로고    scopus 로고
    • Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance
    • 23290777 1:CAS:528:DC%2BC3sXpt1Ons74%3D
    • Liu YY, Hill RA, Li YT (2013) Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance. Adv Cancer Res 117:59-89
    • (2013) Adv Cancer Res , vol.117 , pp. 59-89
    • Liu, Y.Y.1    Hill, R.A.2    Li, Y.T.3
  • 31
    • 43249104789 scopus 로고    scopus 로고
    • Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway
    • 18270325 10.1182/blood-2007-08-106336 1:CAS:528:DC%2BD1cXkvFeitr0%3D
    • Chen CL, Lin CF, Chang WT, Huang WC, Teng CF, Lin YS (2008) Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway. Blood 111:4365-4374
    • (2008) Blood , vol.111 , pp. 4365-4374
    • Chen, C.L.1    Lin, C.F.2    Chang, W.T.3    Huang, W.C.4    Teng, C.F.5    Lin, Y.S.6
  • 32
    • 38149129507 scopus 로고    scopus 로고
    • Ceramide induces p38 MAPK-dependent apoptosis and Bax translocation via inhibition of Akt in HL-60 cells
    • 18054155 10.1016/j.canlet.2007.10.030 1:CAS:528:DC%2BD1cXosFejug%3D%3D
    • Kim HJ, Oh JE, Kim SW, Chun YJ, Kim MY (2008) Ceramide induces p38 MAPK-dependent apoptosis and Bax translocation via inhibition of Akt in HL-60 cells. Cancer Lett 260:88-95
    • (2008) Cancer Lett , vol.260 , pp. 88-95
    • Kim, H.J.1    Oh, J.E.2    Kim, S.W.3    Chun, Y.J.4    Kim, M.Y.5
  • 33
    • 0347537940 scopus 로고    scopus 로고
    • Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
    • 8598911 10.1038/380075a0 1:CAS:528:DyaK28XhsFeisbw%3D
    • Verheij M, Bose R, Lin XH, Yao B, Jarvis WD, Grant S et al (1996) Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature 380:75-79
    • (1996) Nature , vol.380 , pp. 75-79
    • Verheij, M.1    Bose, R.2    Lin, X.H.3    Yao, B.4    Jarvis, W.D.5    Grant, S.6
  • 34
    • 33846833788 scopus 로고    scopus 로고
    • Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells
    • 17222495 10.1016/j.tox.2006.11.005 1:CAS:528:DC%2BD2sXhsFOis7o%3D
    • Hsu SS, Huang CJ, Cheng HH, Chou CT, Lee HY, Wang JL et al (2007) Anandamide-induced Ca2+ elevation leading to p38 MAPK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. Toxicology 231:21-29
    • (2007) Toxicology , vol.231 , pp. 21-29
    • Hsu, S.S.1    Huang, C.J.2    Cheng, H.H.3    Chou, C.T.4    Lee, H.Y.5    Wang, J.L.6
  • 35
    • 0026049696 scopus 로고
    • Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation
    • 2050740 10.1083/jcb.114.1.155 1:CAS:528:DyaK3MXksVKku7c%3D
    • Zhang H, Desai NN, Olivera A, Seki T, Brooker G, Spiegel S (1991) Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J Cell Biol 114:155-167
    • (1991) J Cell Biol , vol.114 , pp. 155-167
    • Zhang, H.1    Desai, N.N.2    Olivera, A.3    Seki, T.4    Brooker, G.5    Spiegel, S.6


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