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Volumn 49, Issue 1, 2014, Pages 16-32

Gene regulation by non-coding RNAs

Author keywords

Gene silencing; LincRNAs; MiRNA; NcRNA; RNA complexes

Indexed keywords

LONG UNTRANSLATED RNA; MICRORNA; PIWI INTERACTING RNA; PIWI PROTEIN; SMALL INTERFERING RNA; UNTRANSLATED RNA;

EID: 84893068058     PISSN: 10409238     EISSN: 15497798     Source Type: Journal    
DOI: 10.3109/10409238.2013.844092     Document Type: Review
Times cited : (144)

References (233)
  • 1
    • 17444430392 scopus 로고    scopus 로고
    • MicroRNAdirected phasing during trans-acting siRNA biogenesis in plants
    • Allen E, Xie Z, Gustafson AM, Carrington JC. (2005). microRNAdirected phasing during trans-acting siRNA biogenesis in plants. Cell 121:207-21.
    • (2005) Cell , vol.121 , pp. 207-221
    • Allen, E.1    Xie, Z.2    Gustafson, A.M.3    Carrington, J.C.4
  • 2
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. (2004). The functions of animal microRNAs. Nature 431: 350-5.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 3
    • 79960924567 scopus 로고    scopus 로고
    • MicroRNAs and developmental timing
    • Ambros V. (2011). MicroRNAs and developmental timing. Curr Opin Genet Dev 21:511-17.
    • (2011) Curr Opin Genet Dev , vol.21 , pp. 511-517
    • Ambros, V.1
  • 4
    • 84857059151 scopus 로고    scopus 로고
    • The tudor domain protein kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila
    • Anand A, Kai T. (2012). The tudor domain protein kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila. EMBO J 31:870-82.
    • (2012) EMBO J , vol.31 , pp. 870-882
    • Anand, A.1    Kai, T.2
  • 5
    • 33745402414 scopus 로고    scopus 로고
    • A novel class of small RNAs bind to MILI protein in mouse testes
    • Aravin A, Gaidatzis D, Pfeffer S, et al. (2006). A novel class of small RNAs bind to MILI protein in mouse testes. Nature 442:203-7.
    • (2006) Nature , vol.442 , pp. 203-207
    • Aravin, A.1    Gaidatzis, D.2    Pfeffer, S.3
  • 6
    • 42149171774 scopus 로고    scopus 로고
    • Small RNA guides for de novo DNA methylation in mammalian germ cells
    • Aravin AA, Bourc'his D. (2008). Small RNA guides for de novo DNA methylation in mammalian germ cells. Genes Dev 22:970-5.
    • (2008) Genes Dev , vol.22 , pp. 970-975
    • Aravin, A.A.1    Bourc'his, D.2
  • 7
    • 0041941514 scopus 로고    scopus 로고
    • The small RNA profile during Drosophila melanogaster development
    • Aravin AA, Lagos-Quintana M, Yalcin A, et al. (2003). The small RNA profile during Drosophila melanogaster development. Dev Cell 5: 337-50.
    • (2003) Dev Cell , vol.5 , pp. 337-350
    • Aravin, A.A.1    Lagos-Quintana, M.2    Yalcin, A.3
  • 8
    • 52049098967 scopus 로고    scopus 로고
    • A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice
    • Aravin AA, Sachidanandam R, Bourc'his D, et al. (2008). A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell 31:785-99.
    • (2008) Mol Cell , vol.31 , pp. 785-799
    • Aravin, A.A.1    Sachidanandam, R.2    Bourc'his, D.3
  • 9
    • 34248160438 scopus 로고    scopus 로고
    • Developmentally regulated piRNA clusters implicate MILI in transposon control
    • Aravin AA, Sachidanandam R, Girard A, et al. (2007). Developmentally regulated piRNA clusters implicate MILI in transposon control. Science 316:744-7.
    • (2007) Science , vol.316 , pp. 744-747
    • Aravin, A.A.1    Sachidanandam, R.2    Girard, A.3
  • 10
    • 84877677064 scopus 로고    scopus 로고
    • Classification and comparison of small RNAs from plants
    • Axtell MJ. (2013). Classification and comparison of small RNAs from plants. Annu Rev Plant Biol 64:137-59.
    • (2013) Annu Rev Plant Biol , vol.64 , pp. 137-159
    • Axtell, M.J.1
  • 11
    • 34248576048 scopus 로고    scopus 로고
    • Design and creation of new nanomaterials for therapeutic RNAi
    • Baigude H, McCarroll J, Yang CS, et al. (2007). Design and creation of new nanomaterials for therapeutic RNAi. ACS Chem Biol 2:237-41.
    • (2007) ACS Chem Biol , vol.2 , pp. 237-241
    • Baigude, H.1    McCarroll, J.2    Yang, C.S.3
  • 12
    • 70350540462 scopus 로고    scopus 로고
    • Delivery of therapeutic RNAi by nanovehicles
    • Baigude H, Rana TM. (2009). Delivery of therapeutic RNAi by nanovehicles. Chembiochem 10:2449-54.
    • (2009) Chembiochem , vol.10 , pp. 2449-2454
    • Baigude, H.1    Rana, T.M.2
  • 13
    • 84860724963 scopus 로고    scopus 로고
    • Interfering nanoparticles for silencing microRNAs
    • Baigude H, Rana TM. (2012). Interfering nanoparticles for silencing microRNAs. Methods Enzymol 509:339-53.
    • (2012) Methods Enzymol , vol.509 , pp. 339-353
    • Baigude, H.1    Rana, T.M.2
  • 14
    • 84881406678 scopus 로고    scopus 로고
    • In vivo delivery of RNAi by reducible interfering nanoparticles (iNOPs)
    • [Epub Ahead of print]. doi:10.1021/ml4001003
    • Baigude H, Su J, McCarroll J, Rana TM. (2013). In vivo delivery of RNAi by reducible interfering nanoparticles (iNOPs). ACS Med Chem Lett. [Epub Ahead of print]. doi:10.1021/ml4001003.
    • (2013) ACS Med Chem Lett
    • Baigude, H.1    Su, J.2    McCarroll, J.3    Rana, T.M.4
  • 15
    • 46149114866 scopus 로고    scopus 로고
    • PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C
    • Batista PJ, Ruby JG, Claycomb JM, et al. (2008). PRG-1 and 21U-RNAs interact to form the piRNA complex required for fertility in C. elegans. Mol Cell 31:67-78.
    • (2008) Elegans. Mol Cell , vol.31 , pp. 67-78
    • Batista, P.J.1    Ruby, J.G.2    Claycomb, J.M.3
  • 16
    • 77956882723 scopus 로고    scopus 로고
    • A long nuclearretained non-coding RNA regulates synaptogenesis by modulating gene expression
    • Bernard D, Prasanth KV, Tripathi V, et al. (2010). A long nuclearretained non-coding RNA regulates synaptogenesis by modulating gene expression. EMBO J 29:3082-93.
    • (2010) EMBO J , vol.29 , pp. 3082-3093
    • Bernard, D.1    Prasanth, K.V.2    Tripathi, V.3
  • 17
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E, Caudy AA, Hammond SM, Hannon GJ. (2001). Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409:363-6.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 18
    • 13444262170 scopus 로고    scopus 로고
    • Inhibition of respiratory viruses by nasally administered siRNA
    • Bitko V, Musiyenko A, Shulyayeva O, Barik S. (2005). Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 11:50-5.
    • (2005) Nat Med , vol.11 , pp. 50-55
    • Bitko, V.1    Musiyenko, A.2    Shulyayeva, O.3    Barik, S.4
  • 19
    • 29244490062 scopus 로고    scopus 로고
    • Endogenous siRNAs derived from a pair of natural cis-antisense transcripts regulate salt tolerance in Arabidopsis
    • Borsani O, Zhu J, Verslues PE, et al. (2005). Endogenous siRNAs derived from a pair of natural cis-antisense transcripts regulate salt tolerance in Arabidopsis. Cell 123:1279-91.
    • (2005) Cell , vol.123 , pp. 1279-1291
    • Borsani, O.1    Zhu, J.2    Verslues, P.E.3
  • 20
    • 67349100160 scopus 로고    scopus 로고
    • Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice
    • Boudreau RL, McBride JL, Martins I, et al. (2009). Nonallele-specific silencing of mutant and wild-type huntingtin demonstrates therapeutic efficacy in Huntington's disease mice. Mol Ther 17:1053-63.
    • (2009) Mol Ther , vol.17 , pp. 1053-1063
    • Boudreau, R.L.1    McBride, J.L.2    Martins, I.3
  • 23
    • 33947273235 scopus 로고    scopus 로고
    • Discrete small RNAgenerating loci as master regulators of transposon activity in Drosophila
    • Brennecke J, Aravin AA, Stark A, et al. (2007). Discrete small RNAgenerating loci as master regulators of transposon activity in Drosophila. Cell 128:1089-103.
    • (2007) Cell , vol.128 , pp. 1089-1103
    • Brennecke, J.1    Aravin, A.A.2    Stark, A.3
  • 24
    • 57149104113 scopus 로고    scopus 로고
    • An epigenetic role for maternally inherited piRNAs in transposon silencing
    • Brennecke J, Malone CD, Aravin AA, et al. (2008). An epigenetic role for maternally inherited piRNAs in transposon silencing. Science 322: 1387-92.
    • (2008) Science , vol.322 , pp. 1387-1392
    • Brennecke, J.1    Malone, C.D.2    Aravin, A.A.3
  • 25
    • 67651087321 scopus 로고    scopus 로고
    • Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications
    • Brown BD, Naldini L. (2009). Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications. Nat Rev Genet 10:578-85.
    • (2009) Nat Rev Genet , vol.10 , pp. 578-585
    • Brown, B.D.1    Naldini, L.2
  • 26
    • 20444455464 scopus 로고    scopus 로고
    • Target accessibility dictates the potency of human RISC
    • Brown KM, Chu CY, Rana TM. (2005). Target accessibility dictates the potency of human RISC. Nat Struct Mol Biol 12:469-70.
    • (2005) Nat Struct Mol Biol , vol.12 , pp. 469-470
    • Brown, K.M.1    Chu, C.Y.2    Rana, T.M.3
  • 27
    • 78650696753 scopus 로고    scopus 로고
    • Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk
    • Burd CE, Jeck WR, Liu Y, et al. (2010). Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk. PLoS Genet 6:e1001233.
    • (2010) PLoS Genet , vol.6
    • Burd, C.E.1    Jeck, W.R.2    Liu, Y.3
  • 28
    • 9344235449 scopus 로고    scopus 로고
    • Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
    • Cai X, Hagedorn CH, Cullen BR. (2004). Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10:1957-66.
    • (2004) RNA , vol.10 , pp. 1957-1966
    • Cai, X.1    Hagedorn, C.H.2    Cullen, B.R.3
  • 29
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin GA, Croce CM. (2006). MicroRNA signatures in human cancers. Nat Rev Cancer 6:857-66.
    • (2006) Nat Rev Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 30
    • 34548230885 scopus 로고    scopus 로고
    • Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas
    • Calin GA, Liu CG, Ferracin M, et al. (2007). Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas. Cancer Cell 12:215-29.
    • (2007) Cancer Cell , vol.12 , pp. 215-229
    • Calin, G.A.1    Liu, C.G.2    Ferracin, M.3
  • 31
    • 4143142117 scopus 로고    scopus 로고
    • MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
    • Calin GA, Liu CG, Sevignani C, et al. (2004). MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci USA 101:11755-60.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11755-11760
    • Calin, G.A.1    Liu, C.G.2    Sevignani, C.3
  • 32
    • 24644519490 scopus 로고    scopus 로고
    • The transcriptional landscape of the mammalian genome
    • Carninci P, Kasukawa T, Katayama S, et al. (2005). The transcriptional landscape of the mammalian genome. Science 309:1559-63.
    • (2005) Science , vol.309 , pp. 1559-1563
    • Carninci, P.1    Kasukawa, T.2    Katayama, S.3
  • 33
    • 0036792769 scopus 로고    scopus 로고
    • Fragile X-related protein and VIG associate with the RNA interference machinery
    • Caudy AA, Myers M, Hannon GJ, Hammond SM. (2002). Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev 16:2491-6.
    • (2002) Genes Dev , vol.16 , pp. 2491-2496
    • Caudy, A.A.1    Myers, M.2    Hannon, G.J.3    Hammond, S.M.4
  • 34
    • 34548084302 scopus 로고    scopus 로고
    • The brain cytoplasmic RNA BC1 regulates dopamine D2 receptor-mediated transmission in the striatum
    • Centonze D, Rossi S, Napoli I, et al. (2007). The brain cytoplasmic RNA BC1 regulates dopamine D2 receptor-mediated transmission in the striatum. J Neurosci 27:8885-92.
    • (2007) J Neurosci , vol.27 , pp. 8885-8892
    • Centonze, D.1    Rossi, S.2    Napoli, I.3
  • 35
    • 23644433363 scopus 로고    scopus 로고
    • TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
    • Chendrimada TP, Gregory RI, Kumaraswamy E, et al. (2005). TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436:740-4.
    • (2005) Nature , vol.436 , pp. 740-744
    • Chendrimada, T.P.1    Gregory, R.I.2    Kumaraswamy, E.3
  • 36
    • 33947236349 scopus 로고    scopus 로고
    • Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma
    • Chiosea S, Jelezcova E, Chandran U, et al. (2006). Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma. Am J Pathol 169:1812-20.
    • (2006) Am J Pathol , vol.169 , pp. 1812-1820
    • Chiosea, S.1    Jelezcova, E.2    Chandran, U.3
  • 37
    • 0036752785 scopus 로고    scopus 로고
    • RNAi in human cells: Basic structural and functional features of small interfering RNA
    • Chiu YL, Rana TM. (2002). RNAi in human cells: basic structural and functional features of small interfering RNA. Mol Cell 10:549-61.
    • (2002) Mol Cell , vol.10 , pp. 549-561
    • Chiu, Y.L.1    Rana, T.M.2
  • 38
    • 0041331496 scopus 로고    scopus 로고
    • SiRNA function in RNAi: A chemical modification analysis
    • Chiu YL, Rana TM. (2003). siRNA function in RNAi: a chemical modification analysis. RNA 9:1034-48.
    • (2003) RNA , vol.9 , pp. 1034-1048
    • Chiu, Y.L.1    Rana, T.M.2
  • 39
    • 33745894330 scopus 로고    scopus 로고
    • Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54
    • Chu CY, Rana TM. (2006). Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol 4: e210.
    • (2006) PLoS Biol , vol.4
    • Chu, C.Y.1    Rana, T.M.2
  • 40
    • 34848828540 scopus 로고    scopus 로고
    • Small RNAs: Regulators and guardians of the genome
    • Chu CY, Rana TM. (2007). Small RNAs: regulators and guardians of the genome. J Cell Physiol 213:412-19.
    • (2007) J Cell Physiol , vol.213 , pp. 412-419
    • Chu, C.Y.1    Rana, T.M.2
  • 41
    • 79960911703 scopus 로고    scopus 로고
    • The reality of pervasive transcription
    • discussion e1001102
    • Clark MB, Amaral PP, Schlesinger FJ, et al. (2011). The reality of pervasive transcription. PLoS Biol 9:e1000625; discussion e1001102.
    • (2011) PLoS Biol , vol.9
    • Clark, M.B.1    Amaral, P.P.2    Schlesinger, F.J.3
  • 42
    • 0030885595 scopus 로고    scopus 로고
    • Isolation of quelling-defective (qde) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa
    • Cogoni C, Macino G. (1997). Isolation of quelling-defective (qde) mutants impaired in posttranscriptional transgene-induced gene silencing in Neurospora crassa. Proc Natl Acad Sci USA 94:10233-8.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10233-10238
    • Cogoni, C.1    Macino, G.2
  • 43
    • 44349104241 scopus 로고    scopus 로고
    • An endogenous small interfering RNA pathway in Drosophila
    • Czech B, Malone CD, Zhou R, et al. (2008). An endogenous small interfering RNA pathway in Drosophila. Nature 453:798-802.
    • (2008) Nature , vol.453 , pp. 798-802
    • Czech, B.1    Malone, C.D.2    Zhou, R.3
  • 44
    • 70449127022 scopus 로고    scopus 로고
    • Hierarchical rules for Argonaute loading in Drosophila
    • Czech B, Zhou R, Erlich Y, et al. (2009). Hierarchical rules for Argonaute loading in Drosophila. Mol Cell 36:445-56.
    • (2009) Mol Cell , vol.36 , pp. 445-456
    • Czech, B.1    Zhou, R.2    Erlich, Y.3
  • 45
    • 46149092009 scopus 로고    scopus 로고
    • Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline
    • Das PP, Bagijn MP, Goldstein LD, et al. (2008). Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline. Mol Cell 31:79-90.
    • (2008) Mol Cell , vol.31 , pp. 79-90
    • Das, P.P.1    Bagijn, M.P.2    Goldstein, L.D.3
  • 46
    • 79954580272 scopus 로고    scopus 로고
    • Current prospects for RNA interference-based therapies
    • Davidson BL, McCray JR PB. (2011). Current prospects for RNA interference-based therapies. Nat Rev Genet 12:329-40.
    • (2011) Nat Rev Genet , vol.12 , pp. 329-340
    • Davidson, B.L.1    McCray, J.R.P.B.2
  • 47
    • 84865689559 scopus 로고    scopus 로고
    • Singles engage the RNA interference pathway
    • Davidson BL, Monteys AM. (2012). Singles engage the RNA interference pathway. Cell 150:873-5.
    • (2012) Cell , vol.150 , pp. 873-875
    • Davidson, B.L.1    Monteys, A.M.2
  • 48
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the Microprocessor complex
    • Denli AM, Tops BB, Plasterk RH, et al. (2004). Processing of primary microRNAs by the Microprocessor complex. Nature 432:231-5.
    • (2004) Nature , vol.432 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.2    Plasterk, R.H.3
  • 49
    • 84865727393 scopus 로고    scopus 로고
    • The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression
    • Derrien T, Johnson R, Bussotti G, et al. (2012). The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res 22:1775-89.
    • (2012) Genome Res , vol.22 , pp. 1775-1789
    • Derrien, T.1    Johnson, R.2    Bussotti, G.3
  • 50
    • 77955608799 scopus 로고    scopus 로고
    • RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma
    • Digiusto DL, Krishnan, A, Li L, et al. (2010). RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma. Sci Transl Med 2:36ra43.
    • (2010) Sci Transl Med , vol.2
    • Digiusto, D.L.1    Krishnan, A.2    Li, L.3
  • 51
    • 84865757142 scopus 로고    scopus 로고
    • Landscape of transcription in human cells
    • Djebali S, Davis CA, Merkel A, et al. (2012). Landscape of transcription in human cells. Nature 489:101-8.
    • (2012) Nature , vol.489 , pp. 101-108
    • Djebali, S.1    Davis, C.A.2    Merkel, A.3
  • 52
    • 1642374097 scopus 로고    scopus 로고
    • Specificity of microRNA target selection in translational repression
    • Doench JG, Sharp PA. (2004). Specificity of microRNA target selection in translational repression. Genes Dev 18:504-11.
    • (2004) Genes Dev , vol.18 , pp. 504-511
    • Doench, J.G.1    Sharp, P.A.2
  • 53
    • 14844354250 scopus 로고    scopus 로고
    • Accumulation of miR-155 and BIC RNA in human B cell lymphomas
    • Eis PS, Tam W, Sun L, et al. (2005). Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci USA 102: 3627-32.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3627-3632
    • Eis, P.S.1    Tam, W.2    Sun, L.3
  • 54
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - MicroRNAs with a role in cancer
    • Esquela-Kerscher A, Slack FJ. (2006). Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 6:259-69.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 55
    • 77953629046 scopus 로고    scopus 로고
    • Regulation of mRNA translation and stability by microRNAs
    • Fabian MR, Sonenberg N, Filipowicz W. (2010). Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem 79: 351-79.
    • (2010) Annu Rev Biochem , vol.79 , pp. 351-379
    • Fabian, M.R.1    Sonenberg, N.2    Filipowicz, W.3
  • 56
    • 46749083733 scopus 로고    scopus 로고
    • Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase
    • Faghihi MA, Modarresi F, Khalil AM, et al. (2008). Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med 14:723-30.
    • (2008) Nat Med , vol.14 , pp. 723-730
    • Faghihi, M.A.1    Modarresi, F.2    Khalil, A.M.3
  • 57
    • 33744804277 scopus 로고    scopus 로고
    • The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator
    • Feng J, Bi C, Clark BS, et al. (2006). The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. Genes Dev 20:1470-84.
    • (2006) Genes Dev , vol.20 , pp. 1470-1484
    • Feng, J.1    Bi, C.2    Clark, B.S.3
  • 58
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, et al. (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391:806-11.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3
  • 59
    • 22744433240 scopus 로고    scopus 로고
    • Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
    • Forstemann K, Tomari Y, Du T, et al. (2005). Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol 3:e236.
    • (2005) PLoS Biol , vol.3
    • Forstemann, K.1    Tomari, Y.2    Du, T.3
  • 60
    • 84865844316 scopus 로고    scopus 로고
    • Decoding the human genome
    • Frazer KA. (2012). Decoding the human genome. Genome Res 22: 1599-601.
    • (2012) Genome Res , vol.22 , pp. 1599-1601
    • Frazer, K.A.1
  • 61
    • 33645532828 scopus 로고    scopus 로고
    • Regulation of apoptosis by a prostate-specific and prostate cancer-associated noncoding gene, PCGEM1
    • Fu X, Ravindranath L, Tran N, et al. (2006). Regulation of apoptosis by a prostate-specific and prostate cancer-associated noncoding gene, PCGEM1. DNA Cell Biol 25:135-41.
    • (2006) DNA Cell Biol , vol.25 , pp. 135-141
    • Fu, X.1    Ravindranath, L.2    Tran, N.3
  • 62
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in cancer: Rationale, strategies and challenges
    • Garzon R, Marcucci G, Croce CM. (2010). Targeting microRNAs in cancer: rationale, strategies and challenges. Nat Rev Drug Discov 9: 775-89.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, C.M.3
  • 63
    • 1842427153 scopus 로고    scopus 로고
    • Use of siRNAs to prevent and treat influenza virus infection
    • Ge Q, Eisen HN, Chen J. (2004a). Use of siRNAs to prevent and treat influenza virus infection. Virus Res 102:37-42.
    • (2004) Virus Res , vol.102 , pp. 37-42
    • Ge, Q.1    Eisen, H.N.2    Chen, J.3
  • 64
    • 2942530436 scopus 로고    scopus 로고
    • Inhibition of influenza virus production in virus-infected mice by RNA interference
    • Ge Q, Filip L, Bai A, et al. (2004b). Inhibition of influenza virus production in virus-infected mice by RNA interference. Proc Natl Acad Sci USA 101:8676-81.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8676-8681
    • Ge, Q.1    Filip, L.2    Bai, A.3
  • 65
    • 44449096738 scopus 로고    scopus 로고
    • Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells
    • Ghildiyal M, Seitz H, Horwich MD, et al. (2008). Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells. Science 320:1077-81.
    • (2008) Science , vol.320 , pp. 1077-1081
    • Ghildiyal, M.1    Seitz, H.2    Horwich, M.D.3
  • 66
    • 75649129754 scopus 로고    scopus 로고
    • Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
    • Ghildiyal M, Xu J, Seitz H, et al. (2010). Sorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway. RNA 16:43-56.
    • (2010) RNA , vol.16 , pp. 43-56
    • Ghildiyal, M.1    Xu, J.2    Seitz, H.3
  • 67
    • 58449134534 scopus 로고    scopus 로고
    • Small silencing RNAs: An expanding universe
    • Ghildiyal M, Zamore PD. (2009). Small silencing RNAs: an expanding universe. Nat Rev Genet 10:94-108.
    • (2009) Nat Rev Genet , vol.10 , pp. 94-108
    • Ghildiyal, M.1    Zamore, P.D.2
  • 68
    • 77956633064 scopus 로고    scopus 로고
    • Design and assembly of new nonviral RNAi delivery agents by microwave-assisted quaternization (MAQ) of tertiary amines
    • Ghosh A, Mukherjee K, Jiang X, et al. (2010). Design and assembly of new nonviral RNAi delivery agents by microwave-assisted quaternization (MAQ) of tertiary amines. Bioconjugate Chem 21:1581-7.
    • (2010) Bioconjugate Chem , vol.21 , pp. 1581-1587
    • Ghosh, A.1    Mukherjee, K.2    Jiang, X.3
  • 69
    • 33745336617 scopus 로고    scopus 로고
    • A germline-specific class of small RNAs binds mammalian Piwi proteins
    • Girard A, Sachidanandam R, Hannon GJ, Carmell MA. (2006). A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature 442:199-202.
    • (2006) Nature , vol.442 , pp. 199-202
    • Girard, A.1    Sachidanandam, R.2    Hannon, G.J.3    Carmell, M.A.4
  • 70
    • 33748303049 scopus 로고    scopus 로고
    • Non-coding-RNA regulators of RNA polymerase II transcription
    • Goodrich JA, Kugel JF. (2006). Non-coding-RNA regulators of RNA polymerase II transcription. Nat Rev Mol Cell Biol 7:612-16.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 612-616
    • Goodrich, J.A.1    Kugel, J.F.2
  • 71
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. (2005). Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123:631-40.
    • (2005) Cell , vol.123 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 72
    • 9144225636 scopus 로고    scopus 로고
    • The Microprocessor complex mediates the genesis of microRNAs
    • Gregory RI, Yan KP, Amuthan G, et al. (2004). The Microprocessor complex mediates the genesis of microRNAs. Nature 432:235-40.
    • (2004) Nature , vol.432 , pp. 235-240
    • Gregory, R.I.1    Yan, K.P.2    Amuthan, G.3
  • 73
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C
    • Grishok A, Pasquinelli AE, Conte D, et al. (2001). Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell 106:23-34.
    • (2001) Elegans Developmental Timing. Cell , vol.106 , pp. 23-34
    • Grishok, A.1    Pasquinelli, A.E.2    Conte, D.3
  • 74
    • 33947390781 scopus 로고    scopus 로고
    • A slicer-mediated mechanism for repeat-associated siRNA 50 end formation in Drosophila
    • Gunawardane LS, Saito K, Nishida KM, et al. (2007). A slicer-mediated mechanism for repeat-associated siRNA 50 end formation in Drosophila. Science 315:1587-90.
    • (2007) Science , vol.315 , pp. 1587-1590
    • Gunawardane, L.S.1    Saito, K.2    Nishida, K.M.3
  • 75
    • 84857066786 scopus 로고    scopus 로고
    • Modular regulatory principles of large non-coding RNAs
    • Guttman M, Rinn JL. (2012). Modular regulatory principles of large non-coding RNAs. Nature 482:339-46.
    • (2012) Nature , vol.482 , pp. 339-346
    • Guttman, M.1    Rinn, J.L.2
  • 76
    • 84877921779 scopus 로고    scopus 로고
    • The piRNA pathway in flies: Highlights and future directions
    • Guzzardo PM, Muerdter F, Hannon GJ. (2013). The piRNA pathway in flies: highlights and future directions. Curr Opin Genet Dev 23: 44-52.
    • (2013) Curr Opin Genet Dev , vol.23 , pp. 44-52
    • Guzzardo, P.M.1    Muerdter, F.2    Hannon, G.J.3
  • 77
    • 0033615491 scopus 로고    scopus 로고
    • A species of small antisense RNA in posttranscriptional gene silencing in plants
    • Hamilton AJ, Baulcombe DC. (1999). A species of small antisense RNA in posttranscriptional gene silencing in plants. Science 286: 950-2.
    • (1999) Science , vol.286 , pp. 950-952
    • Hamilton, A.J.1    Baulcombe, D.C.2
  • 78
    • 0035839109 scopus 로고    scopus 로고
    • Argonaute2, a link between genetic and biochemical analyses of RNAi
    • Hammond SM, Boettcher S, Caudy AA, et al. (2001). Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293: 1146-50.
    • (2001) Science , vol.293 , pp. 1146-1150
    • Hammond, S.M.1    Boettcher, S.2    Caudy, A.A.3
  • 79
    • 10644234841 scopus 로고    scopus 로고
    • The Drosha-DGCR8 complex in primary microRNA processing
    • Han J, Lee Y, Yeom KH, et al. (2004). The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev 18:3016-27.
    • (2004) Genes Dev , vol.18 , pp. 3016-3027
    • Han, J.1    Lee, Y.2    Yeom, K.H.3
  • 80
    • 33744520104 scopus 로고    scopus 로고
    • Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex
    • Han J, Lee Y, Yeom KH, et al. (2006). Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125:887-901.
    • (2006) Cell , vol.125 , pp. 887-901
    • Han, J.1    Lee, Y.2    Yeom, K.H.3
  • 81
    • 84878827621 scopus 로고    scopus 로고
    • The genetic makeup of the Drosophila piRNA pathway
    • Handler D, Meixner K, Pizka M, et al. (2013). The genetic makeup of the Drosophila piRNA pathway. Mol Cell 50:762-77.
    • (2013) Mol Cell , vol.50 , pp. 762-777
    • Handler, D.1    Meixner, K.2    Pizka, M.3
  • 82
    • 84865760395 scopus 로고    scopus 로고
    • GENCODE: The reference human genome annotation for the ENCODE Project
    • Harrow J, Frankish A, Gonzalez JM, et al. (2012). GENCODE: the reference human genome annotation for The ENCODE Project. Genome Res 22:1760-74.
    • (2012) Genome Res , vol.22 , pp. 1760-1774
    • Harrow, J.1    Frankish, A.2    Gonzalez, J.M.3
  • 83
    • 70350569212 scopus 로고    scopus 로고
    • Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences
    • Hartig JV, Esslinger S, Bottcher R, et al. (2009). Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences. EMBO J 28:2932-44.
    • (2009) EMBO J , vol.28 , pp. 2932-2944
    • Hartig, J.V.1    Esslinger, S.2    Bottcher, R.3
  • 84
    • 79954630204 scopus 로고    scopus 로고
    • Loqs-PD and R2D2 define independent pathways for RISC generation in Drosophila
    • Hartig JV, Forstemann K. (2011). Loqs-PD and R2D2 define independent pathways for RISC generation in Drosophila. Nucleic Acids Res 39:3836-51.
    • (2011) Nucleic Acids Res , vol.39 , pp. 3836-3851
    • Hartig, J.V.1    Forstemann, K.2
  • 85
    • 34447291602 scopus 로고    scopus 로고
    • The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC
    • Horwich MD, Li C, Matranga C, et al. (2007). The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr Biol 17:1265-72.
    • (2007) Curr Biol , vol.17 , pp. 1265-1272
    • Horwich, M.D.1    Li, C.2    Matranga, C.3
  • 86
    • 33845609223 scopus 로고    scopus 로고
    • Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: Domain composition, intracellular localization, and function in male germ cells in mice
    • Hosokawa M, Shoji M, Kitamura K, et al. (2007). Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice. Dev Biol 301:38-52.
    • (2007) Dev Biol , vol.301 , pp. 38-52
    • Hosokawa, M.1    Shoji, M.2    Kitamura, K.3
  • 87
    • 34047154356 scopus 로고    scopus 로고
    • A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish
    • Houwing S, Kamminga LM, Berezikov E, et al. (2007). A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell 129:69-82.
    • (2007) Cell , vol.129 , pp. 69-82
    • Houwing, S.1    Kamminga, L.M.2    Berezikov, E.3
  • 88
    • 70349397623 scopus 로고    scopus 로고
    • Targeted RNA interference for hepatic fibrosis
    • Hu PF, Xie WF. (2009). Targeted RNA interference for hepatic fibrosis. Expert Opin Biol Ther 9:1305-12.
    • (2009) Expert Opin Biol Ther , vol.9 , pp. 1305-1312
    • Hu, P.F.1    Xie, W.F.2
  • 89
    • 77955323879 scopus 로고    scopus 로고
    • A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response
    • Huarte M, Guttman M, Feldser D, et al. (2010). A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell 142:409-19.
    • (2010) Cell , vol.142 , pp. 409-419
    • Huarte, M.1    Guttman, M.2    Feldser, D.3
  • 90
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvagner G, McLachlan J, Pasquinelli AE, et al. (2001). A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293:834-8.
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvagner, G.1    McLachlan, J.2    Pasquinelli, A.E.3
  • 91
    • 84868589615 scopus 로고    scopus 로고
    • Biology of Piwi-interacting RNAs: New insights into biogenesis and function inside and outside of germlines
    • Ishizu H, Siomi H, Siomi MC. (2012). Biology of Piwi-interacting RNAs: new insights into biogenesis and function inside and outside of germlines. Genes Dev 26:2361-73.
    • (2012) Genes Dev , vol.26 , pp. 2361-2373
    • Ishizu, H.1    Siomi, H.2    Siomi, M.C.3
  • 92
    • 0036791671 scopus 로고    scopus 로고
    • A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
    • Ishizuka A, Siomi MC, Siomi H. (2002). A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev 16:2497-508.
    • (2002) Genes Dev , vol.16 , pp. 2497-2508
    • Ishizuka, A.1    Siomi, M.C.2    Siomi, H.3
  • 93
    • 77955478739 scopus 로고    scopus 로고
    • Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes
    • Iwasaki S, Kobayashi M, Yoda M, et al. (2010). Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes. Mol Cell 39:292-9.
    • (2010) Mol Cell , vol.39 , pp. 292-299
    • Iwasaki, S.1    Kobayashi, M.2    Yoda, M.3
  • 94
    • 0344429906 scopus 로고    scopus 로고
    • MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer
    • Ji P, Diederichs S, Wang W, et al. (2003). MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene 22: 8031-41.
    • (2003) Oncogene , vol.22 , pp. 8031-8041
    • Ji, P.1    Diederichs, S.2    Wang, W.3
  • 95
    • 7944232720 scopus 로고    scopus 로고
    • RNA and microRNAs in fragile X mental retardation
    • Jin P, Alisch RS, Warren ST. (2004a). RNA and microRNAs in fragile X mental retardation. Nat Cell Biol 6:1048-53.
    • (2004) Nat Cell Biol , vol.6 , pp. 1048-1053
    • Jin, P.1    Alisch, R.S.2    Warren, S.T.3
  • 96
    • 1642540373 scopus 로고    scopus 로고
    • Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
    • Jin P, Zarnescu DC, Ceman S, et al. (2004b). Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci 7:113-17.
    • (2004) Nat Neurosci , vol.7 , pp. 113-117
    • Jin, P.1    Zarnescu, D.C.2    Ceman, S.3
  • 97
    • 65649085603 scopus 로고    scopus 로고
    • Confirming the RNAimediated mechanism of action of siRNA-based cancer therapeutics in mice
    • Judge AD, Robbins M, Tavakoli I, et al. (2009). Confirming the RNAimediated mechanism of action of siRNA-based cancer therapeutics in mice. J Clin Invest 119:661-73.
    • (2009) J Clin Invest , vol.119 , pp. 661-673
    • Judge, A.D.1    Robbins, M.2    Tavakoli, I.3
  • 98
    • 13844294261 scopus 로고    scopus 로고
    • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
    • Kanellopoulou C, Muljo SA, Kung AL, et al. (2005). Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev 19:489-501.
    • (2005) Genes Dev , vol.19 , pp. 489-501
    • Kanellopoulou, C.1    Muljo, S.A.2    Kung, A.L.3
  • 99
    • 34250160256 scopus 로고    scopus 로고
    • RNA maps reveal new RNA classes and a possible function for pervasive transcription
    • Kapranov P, Cheng J, Dike S, et al. (2007). RNA maps reveal new RNA classes and a possible function for pervasive transcription. Science 316:1484-8.
    • (2007) Science , vol.316 , pp. 1484-1488
    • Kapranov, P.1    Cheng, J.2    Dike, S.3
  • 100
    • 20144373433 scopus 로고    scopus 로고
    • Reduced expression of Dicer associated with poor prognosis in lung cancer patients
    • Karube Y, Tanaka H, Osada H, et al. (2005). Reduced expression of Dicer associated with poor prognosis in lung cancer patients. Cancer Sci 96:111-15.
    • (2005) Cancer Sci , vol.96 , pp. 111-115
    • Karube, Y.1    Tanaka, H.2    Osada, H.3
  • 101
  • 102
    • 44349103084 scopus 로고    scopus 로고
    • Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells
    • Kawamura Y, Saito K, Kin T, et al. (2008). Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells. Nature 453:793-7.
    • (2008) Nature , vol.453 , pp. 793-797
    • Kawamura, Y.1    Saito, K.2    Kin, T.3
  • 103
    • 80052991624 scopus 로고    scopus 로고
    • 30 end formation of Piwi-interacting RNAs in vitro
    • Kawaoka S, Izumi N, Katsuma S, Tomari Y. (2011). 30 end formation of Piwi-interacting RNAs in vitro. Mol Cell 43:1015-22.
    • (2011) Mol Cell , vol.43 , pp. 1015-1022
    • Kawaoka, S.1    Izumi, N.2    Katsuma, S.3    Tomari, Y.4
  • 104
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C
    • Ketting RF, Fischer SE, Bernstein E, et al. (2001). Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev 15:2654-9.
    • (2001) Elegans. Genes Dev , vol.15 , pp. 2654-2659
    • Ketting, R.F.1    Fischer, S.E.2    Bernstein, E.3
  • 106
    • 0035929322 scopus 로고    scopus 로고
    • A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans
    • Knight SW, Bass BL. (2001). A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293:2269-71.
    • (2001) Science , vol.293 , pp. 2269-2271
    • Knight, S.W.1    Bass, B.L.2
  • 107
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol J, Loedige I, Filipowicz W. (2010). The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11: 597-610.
    • (2010) Nat Rev Genet , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 108
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with 'antagomirs'
    • Krutzfeldt J, Rajewsky N, Braich R, et al. (2005). Silencing of microRNAs in vivo with 'antagomirs'. Nature 438:685-9.
    • (2005) Nature , vol.438 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 109
    • 36849077497 scopus 로고    scopus 로고
    • Regulation of microRNA expression: The hypoxic component
    • Kulshreshtha R, Ferracin M, Negrini M, et al. (2007a). Regulation of microRNA expression: the hypoxic component. Cell Cycle 6: 1426-31.
    • (2007) Cell Cycle , vol.6 , pp. 1426-1431
    • Kulshreshtha, R.1    Ferracin, M.2    Negrini, M.3
  • 111
    • 10744223519 scopus 로고    scopus 로고
    • Mili, a mammalian member of piwi family gene, is essential for spermatogenesis
    • Kuramochi-Miyagawa S, Kimura T, Ijiri TW, et al. (2004). Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development 131:839-49.
    • (2004) Development , vol.131 , pp. 839-849
    • Kuramochi-Miyagawa, S.1    Kimura, T.2    Ijiri, T.W.3
  • 112
    • 0034829922 scopus 로고    scopus 로고
    • Two mouse piwi-related genes: Miwi and mili
    • Kuramochi-Miyagawa S, Kimura T, Yomogida K, et al. (2001). Two mouse piwi-related genes: miwi and mili. Mech Dev 108: 121-33.
    • (2001) Mech Dev , vol.108 , pp. 121-133
    • Kuramochi-Miyagawa, S.1    Kimura, T.2    Yomogida, K.3
  • 113
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander ES, Linton LM, Birren B, et al. (2001). Initial sequencing and analysis of the human genome. Nature 409:860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2    Birren, B.3
  • 114
    • 74249112787 scopus 로고    scopus 로고
    • Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
    • Lanford RE, Hildebrandt-Eriksen ES, Petri A, et al. (2010). Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327:198-201.
    • (2010) Science , vol.327 , pp. 198-201
    • Lanford, R.E.1    Hildebrandt-Eriksen, E.S.2    Petri, A.3
  • 115
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau NC, Lim LP, Weinstein EG, Bartel DP. (2001). An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294:858-62.
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 116
    • 33746527679 scopus 로고    scopus 로고
    • Characterization of the piRNA complex from rat testes
    • Lau NC, Seto AG, Kim J, et al. (2006). Characterization of the piRNA complex from rat testes. Science 313:363-7.
    • (2006) Science , vol.313 , pp. 363-367
    • Lau, N.C.1    Seto, A.G.2    Kim, J.3
  • 117
    • 84874230944 scopus 로고    scopus 로고
    • Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state
    • Le Thomas A, Rogers AK, Webster A, et al. (2013). Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state. Genes Dev 27:390-9.
    • (2013) Genes Dev , vol.27 , pp. 390-399
    • Le Thomas, A.1    Rogers, A.K.2    Webster, A.3
  • 118
    • 84875177348 scopus 로고    scopus 로고
    • X-inactivation, imprinting, and long noncoding RNAs in health and disease
    • Lee JT, Bartolomei MS. (2013). X-inactivation, imprinting, and long noncoding RNAs in health and disease. Cell 152:1308-23.
    • (2013) Cell , vol.152 , pp. 1308-1323
    • Lee, J.T.1    Bartolomei, M.S.2
  • 119
    • 0027751663 scopus 로고
    • The C. Elegans heterochronic gene lin- 4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V. (1993). The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-54.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 120
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • Lee Y, Ahn C, Han J, et al. (2003). The nuclear RNase III Drosha initiates microRNA processing. Nature 425:415-19.
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1    Ahn, C.2    Han, J.3
  • 121
    • 32544460452 scopus 로고    scopus 로고
    • The role of PACT in the RNA silencing pathway
    • Lee Y, Hur I, Park SY, et al. (2006). The role of PACT in the RNA silencing pathway. EMBO J 25:522-32.
    • (2006) EMBO J , vol.25 , pp. 522-532
    • Lee, Y.1    Hur, I.2    Park, S.Y.3
  • 122
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee Y, Kim M, Han J, et al. (2004a). MicroRNA genes are transcribed by RNA polymerase II. EMBO J 23:4051-60.
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3
  • 123
    • 1842816517 scopus 로고    scopus 로고
    • Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
    • Lee YS, Nakahara K, Pham JW, et al. (2004b). Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117:69-81.
    • (2004) Cell , vol.117 , pp. 69-81
    • Lee, Y.S.1    Nakahara, K.2    Pham, J.W.3
  • 124
    • 3943107461 scopus 로고    scopus 로고
    • Role of a neuronal small non-messenger RNA: Behavioural alterations in BC1 RNAdeleted mice
    • Lewejohann L, Skryabin BV, Sachser N, et al. (2004). Role of a neuronal small non-messenger RNA: behavioural alterations in BC1 RNAdeleted mice. Behav Brain Res 154:273-89.
    • (2004) Behav Brain Res , vol.154 , pp. 273-289
    • Lewejohann, L.1    Skryabin, B.V.2    Sachser, N.3
  • 125
    • 0346094457 scopus 로고    scopus 로고
    • Prediction of mammalian microRNA targets
    • Lewis BP, Shih IH, Jones-Rhoades MW, et al. (2003). Prediction of mammalian microRNA targets. Cell 115:787-98.
    • (2003) Cell , vol.115 , pp. 787-798
    • Lewis, B.P.1    Shih, I.H.2    Jones-Rhoades, M.W.3
  • 126
    • 24744466699 scopus 로고    scopus 로고
    • Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque
    • Li BJ, Tang Q, Cheng D, et al. (2005). Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat Med 11:944-51.
    • (2005) Nat Med , vol.11 , pp. 944-951
    • Li, B.J.1    Tang, Q.2    Cheng, D.3
  • 127
    • 65549118489 scopus 로고    scopus 로고
    • Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies
    • Li C, Vagin VV, Lee S, et al. (2009). Collapse of germline piRNAs in the absence of Argonaute3 reveals somatic piRNAs in flies. Cell 137: 509-21.
    • (2009) Cell , vol.137 , pp. 509-521
    • Li, C.1    Vagin, V.V.2    Lee, S.3
  • 128
    • 0037123630 scopus 로고    scopus 로고
    • Induction and suppression of RNA silencing by an animal virus
    • Li H, Li WX, Ding SW. (2002). Induction and suppression of RNA silencing by an animal virus. Science 296:1319-21.
    • (2002) Science , vol.296 , pp. 1319-1321
    • Li, H.1    Li, W.X.2    Ding, S.W.3
  • 129
    • 0030999967 scopus 로고    scopus 로고
    • Expression of the putative proto-oncogene His-1 in normal and neoplastic tissues
    • Li J, Witte DP, van Dyke T, Askew DS. (1997). Expression of the putative proto-oncogene His-1 in normal and neoplastic tissues. Am J Pathol 150:1297-305.
    • (1997) Am J Pathol , vol.150 , pp. 1297-1305
    • Li, J.1    Witte, D.P.2    Van Dyke, T.3    Askew, D.S.4
  • 130
    • 84863932966 scopus 로고    scopus 로고
    • Molecular mechanisms of RNA-triggered gene silencing machineries
    • Li Z, Rana TM. (2012). Molecular mechanisms of RNA-triggered gene silencing machineries. Acc Chem Res 45:1122-31.
    • (2012) Acc Chem Res , vol.45 , pp. 1122-1131
    • Li, Z.1    Rana, T.M.2
  • 131
    • 34249849029 scopus 로고    scopus 로고
    • Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster
    • Lim AK, Kai T. (2007). Unique germ-line organelle, nuage, functions to repress selfish genetic elements in Drosophila melanogaster. Proc Natl Acad Sci USA 104:6714-19.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 6714-6719
    • Lim, A.K.1    Kai, T.2
  • 132
    • 84865682650 scopus 로고    scopus 로고
    • Single-stranded siRNAs activate RNAi in animals
    • Lima WF, Prakash TP, Murray HM, et al. (2012). Single-stranded siRNAs activate RNAi in animals. Cell 150:883-94.
    • (2012) Cell , vol.150 , pp. 883-894
    • Lima, W.F.1    Prakash, T.P.2    Murray, H.M.3
  • 133
    • 33846950027 scopus 로고    scopus 로고
    • A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas
    • Lin R, Maeda S, Liu C, et al. (2007). A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas. Oncogene 26:851-8.
    • (2007) Oncogene , vol.26 , pp. 851-858
    • Lin, R.1    Maeda, S.2    Liu, C.3
  • 134
    • 0141868916 scopus 로고    scopus 로고
    • R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
    • Liu Q, Rand TA, Kalidas S, et al. (2003). R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301:1921-5.
    • (2003) Science , vol.301 , pp. 1921-1925
    • Liu, Q.1    Rand, T.A.2    Kalidas, S.3
  • 135
    • 68449090733 scopus 로고    scopus 로고
    • C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation
    • Liu Y, Ye X, Jiang F, et al. (2009). C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation. Science 325:750-3.
    • (2009) Science , vol.325 , pp. 750-753
    • Liu, Y.1    Ye, X.2    Jiang, F.3
  • 136
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu J, Getz G, Miska EA, et al. (2005a). MicroRNA expression profiles classify human cancers. Nature 435:834-8.
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1    Getz, G.2    Miska, E.A.3
  • 137
    • 23944506789 scopus 로고    scopus 로고
    • Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans
    • Lu R, Maduro M, Li F, et al. (2005b). Animal virus replication and RNAi-mediated antiviral silencing in Caenorhabditis elegans. Nature 436:1040-3.
    • (2005) Nature , vol.436 , pp. 1040-1043
    • Lu, R.1    Maduro, M.2    Li, F.3
  • 138
    • 33847203593 scopus 로고    scopus 로고
    • Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus
    • Lukiw WJ. (2007). Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 18:297-300.
    • (2007) Neuroreport , vol.18 , pp. 297-300
    • Lukiw, W.J.1
  • 139
    • 0347988235 scopus 로고    scopus 로고
    • Nuclear export of microRNA precursors
    • Lund E, Guttinger S, Calado A, et al. (2004). Nuclear export of microRNA precursors. Science 303:95-8.
    • (2004) Science , vol.303 , pp. 95-98
    • Lund, E.1    Guttinger, S.2    Calado, A.3
  • 140
    • 2442679207 scopus 로고    scopus 로고
    • Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain
    • Ma JB, Ye K, Patel DJ. (2004). Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature 429: 318-22.
    • (2004) Nature , vol.429 , pp. 318-322
    • Ma, J.B.1    Ye, K.2    Patel, D.J.3
  • 141
    • 65549105694 scopus 로고    scopus 로고
    • Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary
    • Malone CD, Brennecke J, Dus M, et al. (2009). Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary. Cell 137:522-35.
    • (2009) Cell , vol.137 , pp. 522-535
    • Malone, C.D.1    Brennecke, J.2    Dus, M.3
  • 142
    • 60149098474 scopus 로고    scopus 로고
    • Small RNAs as guardians of the genome
    • Malone CD, Hannon GJ. (2009). Small RNAs as guardians of the genome. Cell 136:656-68.
    • (2009) Cell , vol.136 , pp. 656-668
    • Malone, C.D.1    Hannon, G.J.2
  • 143
    • 33646598385 scopus 로고    scopus 로고
    • Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes
    • Mancini-Dinardo D, Steele SJ, Levorse JM, et al. (2006). Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes. Genes Dev 20:1268-82.
    • (2006) Genes Dev , vol.20 , pp. 1268-1282
    • Mancini-Dinardo, D.1    Steele, S.J.2    Levorse, J.M.3
  • 144
    • 29144431656 scopus 로고    scopus 로고
    • A human, ATP-independent, RISC assembly machine fueled by pre-miRNA
    • Maniataki E, Mourelatos Z. (2005). A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev 19:2979-90.
    • (2005) Genes Dev , vol.19 , pp. 2979-2990
    • Maniataki, E.1    Mourelatos, Z.2
  • 145
    • 77449084674 scopus 로고    scopus 로고
    • Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila
    • Marques JT, Kim K, Wu PH, et al. (2010). Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila. Nat Struct Mol Biol 17:24-30.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 24-30
    • Marques, J.T.1    Kim, K.2    Wu, P.H.3
  • 146
    • 33846930357 scopus 로고    scopus 로고
    • Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript
    • Martianov I, Ramadass A, Serra Barros A, et al. (2007). Repression of the human dihydrofolate reductase gene by a non-coding interfering transcript. Nature 445:666-70.
    • (2007) Nature , vol.445 , pp. 666-670
    • Martianov, I.1    Ramadass, A.2    Serra Barros, A.3
  • 147
    • 27744590896 scopus 로고    scopus 로고
    • Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
    • Matranga C, Tomari Y, Shin C, et al. (2005). Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123:607-20.
    • (2005) Cell , vol.123 , pp. 607-620
    • Matranga, C.1    Tomari, Y.2    Shin, C.3
  • 148
    • 34548555700 scopus 로고    scopus 로고
    • Transcriptional interference: An unexpected layer of complexity in gene regulation
    • Mazo A, Hodgson JW, Petruk S, et al. (2007). Transcriptional interference: an unexpected layer of complexity in gene regulation. J Cell Sci 120:2755-61.
    • (2007) J Cell Sci , vol.120 , pp. 2755-2761
    • Mazo, A.1    Hodgson, J.W.2    Petruk, S.3
  • 149
    • 0037019339 scopus 로고    scopus 로고
    • RNA interference in adult mice
    • McCaffrey AP, Meuse L, Pham TT, et al. (2002). RNA interference in adult mice. Nature 418:38-9.
    • (2002) Nature , vol.418 , pp. 38-39
    • McCaffrey, A.P.1    Meuse, L.2    Pham, T.T.3
  • 150
    • 74949115997 scopus 로고    scopus 로고
    • Nanotubes functionalized with lipids and natural amino acid dendrimers: A new strategy to create nanomaterials for delivering systemic RNAi
    • McCarroll J, Baigude H, Yang CS, Rana TM. (2010). Nanotubes functionalized with lipids and natural amino acid dendrimers: a new strategy to create nanomaterials for delivering systemic RNAi. Bioconjugate Chem 21:56-63.
    • (2010) Bioconjugate Chem , vol.21 , pp. 56-63
    • McCarroll, J.1    Baigude, H.2    Yang, C.S.3    Rana, T.M.4
  • 151
    • 0032813924 scopus 로고    scopus 로고
    • LIT1, an imprinted antisense RNA in the human KvLQT1 locus identified by screening for differentially expressed transcripts using monochromosomal hybrids
    • Mitsuya K, Meguro M, Lee MP, et al. (1999). LIT1, an imprinted antisense RNA in the human KvLQT1 locus identified by screening for differentially expressed transcripts using monochromosomal hybrids. Hum Mol Genet 8:1209-17.
    • (1999) Hum Mol Genet , vol.8 , pp. 1209-1217
    • Mitsuya, K.1    Meguro, M.2    Lee, M.P.3
  • 152
    • 77149173174 scopus 로고    scopus 로고
    • Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila
    • Miyoshi K, Miyoshi T, Hartig JV, et al. (2010). Molecular mechanisms that funnel RNA precursors into endogenous small-interfering RNA and microRNA biogenesis pathways in Drosophila. RNA 16:506-15.
    • (2010) RNA , vol.16 , pp. 506-515
    • Miyoshi, K.1    Miyoshi, T.2    Hartig, J.V.3
  • 153
    • 28444437427 scopus 로고    scopus 로고
    • Slicer function of Drosophila Argonautes and its involvement in RISC formation
    • Miyoshi K, Tsukumo H, Nagami T, et al. (2005). Slicer function of Drosophila Argonautes and its involvement in RISC formation. Genes Dev 19:2837-48.
    • (2005) Genes Dev , vol.19 , pp. 2837-2848
    • Miyoshi, K.1    Tsukumo, H.2    Nagami, T.3
  • 154
    • 58249098615 scopus 로고    scopus 로고
    • GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer
    • Mourtada-Maarabouni M, Pickard MR, Hedge VL, et al. (2009). GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer. Oncogene 28:195-208.
    • (2009) Oncogene , vol.28 , pp. 195-208
    • Mourtada-Maarabouni, M.1    Pickard, M.R.2    Hedge, V.L.3
  • 155
    • 84878847013 scopus 로고    scopus 로고
    • A genome-wide RNAi screen draws a genetic framework for transposon control and primary piRNA biogenesis in Drosophila
    • Muerdter F, Guzzardo PM, Gillis J, et al. (2013). A genome-wide RNAi screen draws a genetic framework for transposon control and primary piRNA biogenesis in Drosophila. Mol Cell 50:736-48.
    • (2013) Mol Cell , vol.50 , pp. 736-748
    • Muerdter, F.1    Guzzardo, P.M.2    Gillis, J.3
  • 156
    • 24744441906 scopus 로고    scopus 로고
    • Characterization of Dicer-deficient murine embryonic stem cells
    • Murchison EP, Partridge JF, Tam OH, et al. (2005). Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci USA 102:12135-40.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 12135-12140
    • Murchison, E.P.1    Partridge, J.F.2    Tam, O.H.3
  • 157
    • 77951977959 scopus 로고    scopus 로고
    • Cricket paralysis virus antagonizes Argonaute 2 to modulate antiviral defense in Drosophila
    • Nayak A, Berry B, Tassetto M, et al. (2010). Cricket paralysis virus antagonizes Argonaute 2 to modulate antiviral defense in Drosophila. Nat Struct Mol Biol 17:547-54.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 547-554
    • Nayak, A.1    Berry, B.2    Tassetto, M.3
  • 158
    • 44349101881 scopus 로고    scopus 로고
    • Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster
    • Okamura K, Balla S, Martin R, et al. (2008). Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Nat Struct Mol Biol 15:998.
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 998
    • Okamura, K.1    Balla, S.2    Martin, R.3
  • 159
    • 70449122099 scopus 로고    scopus 로고
    • Distinct mechanisms for microRNA strand selection by Drosophila Argonautes
    • Okamura K, Liu N, Lai EC. (2009). Distinct mechanisms for microRNA strand selection by Drosophila Argonautes. Mol Cell 36:431-44.
    • (2009) Mol Cell , vol.36 , pp. 431-444
    • Okamura, K.1    Liu, N.2    Lai, E.C.3
  • 160
    • 17444365809 scopus 로고    scopus 로고
    • Local RNA target structure influences siRNA efficacy: A systematic global analysis
    • Overhoff M, Alken M, Far RK, et al. (2005). Local RNA target structure influences siRNA efficacy: a systematic global analysis. J Mol Biol 348:871-81.
    • (2005) J Mol Biol , vol.348 , pp. 871-881
    • Overhoff, M.1    Alken, M.2    Far, R.K.3
  • 161
    • 0023969307 scopus 로고
    • The structure and expression of a novel gene activated in early mouse embryogenesis
    • Pachnis V, Brannan CI, Tilghman SM. (1988). The structure and expression of a novel gene activated in early mouse embryogenesis. EMBO J 7:673-81.
    • (1988) EMBO J , vol.7 , pp. 673-681
    • Pachnis, V.1    Brannan, C.I.2    Tilghman, S.M.3
  • 162
    • 0036796883 scopus 로고    scopus 로고
    • Developmental functions of the Distal-less/Dlx homeobox genes
    • Panganiban G, Rubenstein JL. (2002). Developmental functions of the Distal-less/Dlx homeobox genes. Development 129:4371-86.
    • (2002) Development , vol.129 , pp. 4371-4386
    • Panganiban, G.1    Rubenstein, J.L.2
  • 163
    • 15844402005 scopus 로고    scopus 로고
    • Structural insights into mRNA recognition from a Piwi domain-siRNA guide complex
    • Parker JS, Roe SM, Barford D. (2005). Structural insights into mRNA recognition from a Piwi domain-siRNA guide complex. Nature 434: 663-6.
    • (2005) Nature , vol.434 , pp. 663-666
    • Parker, J.S.1    Roe, S.M.2    Barford, D.3
  • 164
    • 79551623370 scopus 로고    scopus 로고
    • ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS
    • Pasmant E, Sabbagh A, Vidaud M, Bieche I. (2011). ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS. FASEB J 25:444-8.
    • (2011) FASEB J , vol.25 , pp. 444-448
    • Pasmant, E.1    Sabbagh, A.2    Vidaud, M.3    Bieche, I.4
  • 165
    • 0034597777 scopus 로고    scopus 로고
    • Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
    • Pasquinelli AE, Reinhart BJ, Slack F, et al. (2000). Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408:86-9.
    • (2000) Nature , vol.408 , pp. 86-89
    • Pasquinelli, A.E.1    Reinhart, B.J.2    Slack, F.3
  • 166
    • 77951288138 scopus 로고    scopus 로고
    • Repression of retroelements in Drosophila germline via piRNA pathway by the Tudor domain protein Tejas
    • Patil VS, Kai T. (2010). Repression of retroelements in Drosophila germline via piRNA pathway by the Tudor domain protein Tejas. Curr Biol 20:724-30.
    • (2010) Curr Biol , vol.20 , pp. 724-730
    • Patil, V.S.1    Kai, T.2
  • 167
    • 34249099120 scopus 로고    scopus 로고
    • Silencing by imprinted noncoding RNAs: Is transcription the answer?
    • Pauler FM, Koerner MV, Barlow DP. (2007). Silencing by imprinted noncoding RNAs: is transcription the answer? Trends Genet 23: 284-92.
    • (2007) Trends Genet , vol.23 , pp. 284-292
    • Pauler, F.M.1    Koerner, M.V.2    Barlow, D.P.3
  • 168
    • 35349009932 scopus 로고    scopus 로고
    • Interferon modulation of cellular microRNAs as an antiviral mechanism
    • Pedersen IM, Cheng G, Wieland S, et al. (2007). Interferon modulation of cellular microRNAs as an antiviral mechanism. Nature 449: 919-22.
    • (2007) Nature , vol.449 , pp. 919-922
    • Pedersen, I.M.1    Cheng, G.2    Wieland, S.3
  • 169
    • 84861980264 scopus 로고    scopus 로고
    • Tudor domain proteins in development
    • Pek JW, Anand A, Kai T. (2012a). Tudor domain proteins in development. Development 139:2255-66.
    • (2012) Development , vol.139 , pp. 2255-2266
    • Pek, J.W.1    Anand, A.2    Kai, T.3
  • 170
    • 84855957812 scopus 로고    scopus 로고
    • PiRNA pathway and the potential processing site, the nuage, in the Drosophila germline
    • Pek JW, Patil VS, Kai T. (2012b). piRNA pathway and the potential processing site, the nuage, in the Drosophila germline. Dev Growth Differ 54:66-77.
    • (2012) Dev Growth Differ , vol.54 , pp. 66-77
    • Pek, J.W.1    Patil, V.S.2    Kai, T.3
  • 171
    • 33846810192 scopus 로고    scopus 로고
    • A novel repeat-associated small interfering RNA-mediated silencing pathway downregulates complementary sense gypsy transcripts in somatic cells of the Drosophila ovary
    • Pelisson A, Sarot E, Payen-Groschene G, Bucheton A. (2007). A novel repeat-associated small interfering RNA-mediated silencing pathway downregulates complementary sense gypsy transcripts in somatic cells of the Drosophila ovary. J Virol 81:1951-60.
    • (2007) J Virol , vol.81 , pp. 1951-1960
    • Pelisson, A.1    Sarot, E.2    Payen-Groschene, G.3    Bucheton, A.4
  • 172
    • 4644286235 scopus 로고    scopus 로고
    • SGS3 and SGS2/SDE1/ RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis
    • Peragine A, Yoshikawa M, Wu G, et al. (2004). SGS3 and SGS2/SDE1/ RDR6 are required for juvenile development and the production of trans-acting siRNAs in Arabidopsis. Genes Dev 18:2368-79.
    • (2004) Genes Dev , vol.18 , pp. 2368-2379
    • Peragine, A.1    Yoshikawa, M.2    Wu, G.3
  • 173
    • 34249736846 scopus 로고    scopus 로고
    • MicroRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder
    • Perkins DO, Jeffries CD, Jarskog LF, et al. (2007). microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder. Genome Biol 8:R27.
    • (2007) Genome Biol , vol.8
    • Perkins, D.O.1    Jeffries, C.D.2    Jarskog, L.F.3
  • 174
    • 1842766252 scopus 로고    scopus 로고
    • A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila
    • Pham JW, Pellino JL, Lee YS, et al. (2004). A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 117:83-94.
    • (2004) Cell , vol.117 , pp. 83-94
    • Pham, J.W.1    Pellino, J.L.2    Lee, Y.S.3
  • 175
    • 33746852731 scopus 로고    scopus 로고
    • Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs
    • Plante I, Davidovic L, Ouellet DL, et al. (2006). Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs. J Biomed Biotechnol 2006: 64347.
    • (2006) J Biomed Biotechnol , vol.2006 , pp. 64347
    • Plante, I.1    Davidovic, L.2    Ouellet, D.L.3
  • 176
    • 33845755467 scopus 로고    scopus 로고
    • Illuminating the silence: Understanding the structure and function of small RNAs
    • Rana TM. (2007). Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol 8: 23-36.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 23-36
    • Rana, T.M.1
  • 177
    • 27744506761 scopus 로고    scopus 로고
    • Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
    • Rand TA, Petersen S, Du F, Wang X. (2005). Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell 123: 621-9.
    • (2005) Cell , vol.123 , pp. 621-629
    • Rand, T.A.1    Petersen, S.2    Du, F.3    Wang, X.4
  • 178
    • 0034708122 scopus 로고    scopus 로고
    • The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
    • Reinhart BJ, Slack FJ, Basson M, et al. (2000). The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403:901-6.
    • (2000) Nature , vol.403 , pp. 901-906
    • Reinhart, B.J.1    Slack, F.J.2    Basson, M.3
  • 179
    • 83055193640 scopus 로고    scopus 로고
    • Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing
    • Reuter M, Berninger P, Chuma S, et al. (2011). Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing. Nature 480:264-7.
    • (2011) Nature , vol.480 , pp. 264-267
    • Reuter, M.1    Berninger, P.2    Chuma, S.3
  • 180
    • 34250729138 scopus 로고    scopus 로고
    • Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
    • Rinn JL, Kertesz M, Wang JK, et al. (2007). Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell 129:1311-23.
    • (2007) Cell , vol.129 , pp. 1311-1323
    • Rinn, J.L.1    Kertesz, M.2    Wang, J.K.3
  • 181
    • 33845436047 scopus 로고    scopus 로고
    • Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C
    • Ruby JG, Jan C, Player C, et al. (2006). Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell 127:1193-207.
    • (2006) Elegans. Cell , vol.127 , pp. 1193-1207
    • Ruby, J.G.1    Jan, C.2    Player, C.3
  • 182
    • 22744454230 scopus 로고    scopus 로고
    • Processing of premicroRNAs by the Dicer-1-Loquacious complex in Drosophila cells
    • Saito K, Ishizuka A, Siomi H, Siomi MC. (2005). Processing of premicroRNAs by the Dicer-1-Loquacious complex in Drosophila cells. PLoS Biol 3:e235.
    • (2005) PLoS Biol , vol.3
    • Saito, K.1    Ishizuka, A.2    Siomi, H.3    Siomi, M.C.4
  • 183
    • 33747369856 scopus 로고    scopus 로고
    • Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome
    • Saito K, Nishida KM, Mori T, et al. (2006). Specific association of Piwi with rasiRNAs derived from retrotransposon and heterochromatic regions in the Drosophila genome. Genes Dev 20:2214-22.
    • (2006) Genes Dev , vol.20 , pp. 2214-2222
    • Saito, K.1    Nishida, K.M.2    Mori, T.3
  • 184
    • 34347378274 scopus 로고    scopus 로고
    • Pimet, the Drosophila homolog of HEN1, mediates 20-O-methylation of Piwi-interacting RNAs at their 30 ends
    • Saito K, Sakaguchi Y, Suzuki T, et al. (2007). Pimet, the Drosophila homolog of HEN1, mediates 20-O-methylation of Piwi-interacting RNAs at their 30 ends. Genes Dev 21:1603-8.
    • (2007) Genes Dev , vol.21 , pp. 1603-1608
    • Saito, K.1    Sakaguchi, Y.2    Suzuki, T.3
  • 185
    • 33644514069 scopus 로고    scopus 로고
    • Noncoding RNAs of trithorax response elements recruit Drosophila Ash1 to Ultrabithorax
    • Sanchez-Elsner T, Gou D, Kremmer E, Sauer F. (2006). Noncoding RNAs of trithorax response elements recruit Drosophila Ash1 to Ultrabithorax. Science 311:1118-23.
    • (2006) Science , vol.311 , pp. 1118-1123
    • Sanchez-Elsner, T.1    Gou, D.2    Kremmer, E.3    Sauer, F.4
  • 186
    • 84855295489 scopus 로고    scopus 로고
    • Deep sequencing of virus-infected cells reveals HIV-encoded small RNAs
    • Schopman NC, Willemsen M, Liu YP, et al. (2012). Deep sequencing of virus-infected cells reveals HIV-encoded small RNAs. Nucleic Acids Res 40:414-27.
    • (2012) Nucleic Acids Res , vol.40 , pp. 414-427
    • Schopman, N.C.1    Willemsen, M.2    Liu, Y.P.3
  • 187
    • 17444412299 scopus 로고    scopus 로고
    • Local RNA target structure influences siRNA efficacy: Systematic analysis of intentionally designed binding regions
    • Schubert S, Grunweller A, Erdmann VA, Kurreck J. (2005). Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions. J Mol Biol 348:883-93.
    • (2005) J Mol Biol , vol.348 , pp. 883-893
    • Schubert, S.1    Grunweller, A.2    Erdmann, V.A.3    Kurreck, J.4
  • 188
    • 71649101009 scopus 로고    scopus 로고
    • The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline
    • Shoji M, Tanaka T, Hosokawa M, et al. (2009). The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell 17:775-87.
    • (2009) Dev Cell , vol.17 , pp. 775-787
    • Shoji, M.1    Tanaka, T.2    Hosokawa, M.3
  • 189
    • 0037075032 scopus 로고    scopus 로고
    • The non-coding Air RNA is required for silencing autosomal imprinted genes
    • Sleutels F, Zwart R, Barlow DP. (2002). The non-coding Air RNA is required for silencing autosomal imprinted genes. Nature 415:810-13.
    • (2002) Nature , vol.415 , pp. 810-813
    • Sleutels, F.1    Zwart, R.2    Barlow, D.P.3
  • 190
    • 0031756336 scopus 로고    scopus 로고
    • Classification of gas5 as a multi-smallnucleolar- RNA (snoRNA) host gene and a member of the 50-terminal oligopyrimidine gene family reveals common features of snoRNA host genes
    • Smith CM, Steitz JA. (1998). Classification of gas5 as a multi-smallnucleolar- RNA (snoRNA) host gene and a member of the 50-terminal oligopyrimidine gene family reveals common features of snoRNA host genes. Mol Cell Biol 18:6897-909.
    • (1998) Mol Cell Biol , vol.18 , pp. 6897-6909
    • Smith, C.M.1    Steitz, J.A.2
  • 191
    • 36349032759 scopus 로고    scopus 로고
    • MicroRNAs in disease and potential therapeutic applications
    • Soifer HS, Rossi JJ, Saetrom P. (2007). MicroRNAs in disease and potential therapeutic applications. Mol Ther 15:2070-9.
    • (2007) Mol Ther , vol.15 , pp. 2070-2079
    • Soifer, H.S.1    Rossi, J.J.2    Saetrom, P.3
  • 192
    • 0345490960 scopus 로고    scopus 로고
    • The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes
    • Song JJ, Liu J, Tolia NH, et al. (2003). The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat Struct Biol 10:1026-32.
    • (2003) Nat Struct Biol , vol.10 , pp. 1026-1032
    • Song, J.J.1    Liu, J.2    Tolia, N.H.3
  • 193
    • 4444302947 scopus 로고    scopus 로고
    • Crystal structure of Argonaute and its implications for RISC slicer activity
    • Song JJ, Smith SK, Hannon GJ, Joshua-Tor L. (2004). Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305:1434-7.
    • (2004) Science , vol.305 , pp. 1434-1437
    • Song, J.J.1    Smith, S.K.2    Hannon, G.J.3    Joshua-Tor, L.4
  • 194
    • 84865859048 scopus 로고    scopus 로고
    • What does our genome encode?
    • Stamatoyannopoulos JA. (2012). What does our genome encode? Genome Res 22:1602-11.
    • (2012) Genome Res , vol.22 , pp. 1602-1611
    • Stamatoyannopoulos, J.A.1
  • 195
    • 48949118193 scopus 로고    scopus 로고
    • Control over the morphology and segregation of Zebrafish germ cell granules during embryonic development
    • Strasser MJ, Mackenzie NC, Dumstrei K, et al. (2008). Control over the morphology and segregation of Zebrafish germ cell granules during embryonic development. BMC Dev Biol 8:58.
    • (2008) BMC Dev Biol , vol.8 , pp. 58
    • Strasser, M.J.1    Mackenzie, N.C.2    Dumstrei, K.3
  • 196
    • 33846984935 scopus 로고    scopus 로고
    • Transcriptional noise and the fidelity of initiation by RNA polymerase II
    • Struhl K. (2007). Transcriptional noise and the fidelity of initiation by RNA polymerase II. Nat Struct Mol Biol 14:103-5.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 103-105
    • Struhl, K.1
  • 198
    • 9644274030 scopus 로고    scopus 로고
    • The clinical, immunological, and molecular spectrum of chromosome 22q11.2 deletion syndrome and DiGeorge syndrome
    • Sullivan KE. (2004a). The clinical, immunological, and molecular spectrum of chromosome 22q11.2 deletion syndrome and DiGeorge syndrome. Curr Opin Allergy Clin Immunol 4:505-12.
    • (2004) Curr Opin Allergy Clin Immunol , vol.4 , pp. 505-512
    • Sullivan, K.E.1
  • 199
    • 19544390850 scopus 로고    scopus 로고
    • Live viral vaccines in patients with DiGeorge syndrome
    • Sullivan KE. (2004b). Live viral vaccines in patients with DiGeorge syndrome. Clin Immunol 113:3.
    • (2004) Clin Immunol , vol.113 , pp. 3
    • Sullivan, K.E.1
  • 200
    • 44349159416 scopus 로고    scopus 로고
    • Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes
    • Tam OH, Aravin AA, Stein P, et al. (2008). Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes. Nature 453:534-8.
    • (2008) Nature , vol.453 , pp. 534-538
    • Tam, O.H.1    Aravin, A.A.2    Stein, P.3
  • 201
    • 8844271740 scopus 로고    scopus 로고
    • A protein sensor for siRNA asymmetry
    • Tomari Y, Matranga C, Haley B, et al. (2004). A protein sensor for siRNA asymmetry. Science 306:1377-80.
    • (2004) Science , vol.306 , pp. 1377-1380
    • Tomari, Y.1    Matranga, C.2    Haley, B.3
  • 202
    • 2942620143 scopus 로고    scopus 로고
    • Protection against lethal influenza virus challenge by RNA interference in vivo
    • Tompkins SM, Lo CY, Tumpey TM, Epstein SL. (2004). Protection against lethal influenza virus challenge by RNA interference in vivo. Proc Natl Acad Sci USA 101:8682-6.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8682-8686
    • Tompkins, S.M.1    Lo, C.Y.2    Tumpey, T.M.3    Epstein, S.L.4
  • 203
    • 77956927823 scopus 로고    scopus 로고
    • The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation
    • Tripathi V, Ellis JD, Shen Z, et al. (2010). The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol Cell 39:925-38.
    • (2010) Mol Cell , vol.39 , pp. 925-938
    • Tripathi, V.1    Ellis, J.D.2    Shen, Z.3
  • 204
    • 77954572735 scopus 로고    scopus 로고
    • Long noncoding RNA as modular scaffold of histone modification complexes
    • Tsai MC, Manor O, Wan Y, et al. (2010). Long noncoding RNA as modular scaffold of histone modification complexes. Science 329: 689-93.
    • (2010) Science , vol.329 , pp. 689-693
    • Tsai, M.C.1    Manor, O.2    Wan, Y.3
  • 205
    • 9644281546 scopus 로고    scopus 로고
    • Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes
    • Umlauf D, Goto Y, Cao R, et al. (2004). Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes. Nat Genet 36: 1296-300.
    • (2004) Nat Genet , vol.36 , pp. 1296-1300
    • Umlauf, D.1    Goto, Y.2    Cao, R.3
  • 206
    • 33746502166 scopus 로고    scopus 로고
    • A distinct small RNA pathway silences selfish genetic elements in the germline
    • Vagin VV, Sigova A, Li C, et al. (2006). A distinct small RNA pathway silences selfish genetic elements in the germline. Science 313:320-4.
    • (2006) Science , vol.313 , pp. 320-324
    • Vagin, V.V.1    Sigova, A.2    Li, C.3
  • 207
    • 68149164399 scopus 로고    scopus 로고
    • Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members
    • Vagin VV, Wohlschlegel J, Qu J, et al. (2009). Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes Dev 23: 1749-62.
    • (2009) Genes Dev , vol.23 , pp. 1749-1762
    • Vagin, V.V.1    Wohlschlegel, J.2    Qu, J.3
  • 208
    • 33751120715 scopus 로고    scopus 로고
    • The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster
    • van Rij RP, Saleh MC, Berry B, et al. (2006). The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster. Genes Dev 20:2985-95.
    • (2006) Genes Dev , vol.20 , pp. 2985-2995
    • Van Rij, R.P.1    Saleh, M.C.2    Berry, B.3
  • 209
    • 84868475728 scopus 로고    scopus 로고
    • MicroRNA therapeutics for cardiovascular disease: Opportunities and obstacles
    • van Rooij E, Olson, EN. (2012). MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles. Nature Rev Drug Discov 11:860-72.
    • (2012) Nature Rev Drug Discov , vol.11 , pp. 860-872
    • Van Rooij, E.1    Olson, E.N.2
  • 210
    • 4944225347 scopus 로고    scopus 로고
    • Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs
    • Vazquez F, Vaucheret H, Rajagopalan R, et al. (2004). Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs. Mol Cell 16:69-79.
    • (2004) Mol Cell , vol.16 , pp. 69-79
    • Vazquez, F.1    Vaucheret, H.2    Rajagopalan, R.3
  • 211
    • 33144490646 scopus 로고    scopus 로고
    • A microRNA expression signature of human solid tumors defines cancer gene targets
    • Volinia S, Calin GA, Liu CG, et al. (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103:2257-61.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2257-2261
    • Volinia, S.1    Calin, G.A.2    Liu, C.G.3
  • 212
    • 45449118682 scopus 로고    scopus 로고
    • A C. Elegans Piwi, PRG-1, regulates 21U-RNAs during spermatogenesis
    • Wang G, Reinke V. (2008). A C. elegans Piwi, PRG-1, regulates 21U-RNAs during spermatogenesis. Curr Biol 18:861-7.
    • (2008) Curr Biol , vol.18 , pp. 861-867
    • Wang, G.1    Reinke, V.2
  • 213
    • 47049099443 scopus 로고    scopus 로고
    • Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression
    • Wang H, Ghosh A, Baigude H, et al. (2008a). Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression. J Biol Chem 283:15845-52.
    • (2008) J Biol Chem , vol.283 , pp. 15845-15852
    • Wang, H.1    Ghosh, A.2    Baigude, H.3
  • 214
    • 46649093597 scopus 로고    scopus 로고
    • Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription
    • Wang X, Arai S, Song X, et al. (2008b). Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature 454:126-30.
    • (2008) Nature , vol.454 , pp. 126-130
    • Wang, X.1    Arai, S.2    Song, X.3
  • 215
    • 28544432929 scopus 로고    scopus 로고
    • Dendritic BC1 RNA in translational control mechanisms
    • Wang H, Iacoangeli A, Lin D, et al. (2005). Dendritic BC1 RNA in translational control mechanisms. J Cell Biol 171:811-21.
    • (2005) J Cell Biol , vol.171 , pp. 811-821
    • Wang, H.1    Iacoangeli, A.2    Lin, D.3
  • 216
    • 33645979325 scopus 로고    scopus 로고
    • RNA interference directs innate immunity against viruses in adult Drosophila
    • Wang XH, Aliyari R, Li WX, et al. (2006). RNA interference directs innate immunity against viruses in adult Drosophila. Science 312: 452-4.
    • (2006) Science , vol.312 , pp. 452-454
    • Wang, X.H.1    Aliyari, R.2    Li, W.X.3
  • 217
    • 70349961432 scopus 로고    scopus 로고
    • Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes
    • Wang Y, Juranek S, Li H, et al. (2009). Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature 461: 754-61.
    • (2009) Nature , vol.461 , pp. 754-761
    • Wang, Y.1    Juranek, S.2    Li, H.3
  • 218
    • 79957840356 scopus 로고    scopus 로고
    • Long noncoding RNAs and human disease
    • Wapinski O, Chang HY. (2011). Long noncoding RNAs and human disease. Trends Cell Biol 21:354-61.
    • (2011) Trends Cell Biol , vol.21 , pp. 354-361
    • Wapinski, O.1    Chang, H.Y.2
  • 219
    • 44349130233 scopus 로고    scopus 로고
    • Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes
    • Watanabe T, Totoki Y, Toyoda A, et al. (2008). Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature 453:539-43.
    • (2008) Nature , vol.453 , pp. 539-543
    • Watanabe, T.1    Totoki, Y.2    Toyoda, A.3
  • 220
    • 0036773286 scopus 로고    scopus 로고
    • Dexamethasone and tumor necrosis factor-alpha act together to induce the cellular inhibitor of apoptosis-2 gene and prevent apoptosis in a variety of cell types
    • Webster JC, Huber RM, Hanson RL, et al. (2002). Dexamethasone and tumor necrosis factor-alpha act together to induce the cellular inhibitor of apoptosis-2 gene and prevent apoptosis in a variety of cell types. Endocrinology 143:3866-74.
    • (2002) Endocrinology , vol.143 , pp. 3866-3874
    • Webster, J.C.1    Huber, R.M.2    Hanson, R.L.3
  • 221
    • 22144433672 scopus 로고    scopus 로고
    • A database analysis method identifies an endogenous trans-acting short-interfering RNA that targets the Arabidopsis ARF2, ARF3, and ARF4 genes
    • Williams L, Carles CC, Osmont KS, Fletcher JC. (2005). A database analysis method identifies an endogenous trans-acting short-interfering RNA that targets the Arabidopsis ARF2, ARF3, and ARF4 genes. Proc Natl Acad Sci USA 102:9703-8.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 9703-9708
    • Williams, L.1    Carles, C.C.2    Osmont, K.S.3    Fletcher, J.C.4
  • 222
    • 77649221027 scopus 로고    scopus 로고
    • Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer
    • Wojcik SE, Rossi S, Shimizu M, et al. (2010). Non-codingRNA sequence variations in human chronic lymphocytic leukemia and colorectal cancer. Carcinogenesis 31:208-15.
    • (2010) Carcinogenesis , vol.31 , pp. 208-215
    • Wojcik, S.E.1    Rossi, S.2    Shimizu, M.3
  • 223
    • 0036787671 scopus 로고    scopus 로고
    • SiRNA-mediated gene silencing in vitro and in vivo
    • Xia H, Mao Q, Paulson HL, Davidson BL. (2002). siRNA-mediated gene silencing in vitro and in vivo. Nat Biotechnol 20:1006-10.
    • (2002) Nat Biotechnol , vol.20 , pp. 1006-1010
    • Xia, H.1    Mao, Q.2    Paulson, H.L.3    Davidson, B.L.4
  • 224
    • 19344374219 scopus 로고    scopus 로고
    • Genetic and functional diversification of small RNA pathways in plants
    • Xie Z, Johansen LK, Gustafson AM, et al. (2004). Genetic and functional diversification of small RNA pathways in plants. PLoS Biol 2:E104.
    • (2004) PLoS Biol , vol.2
    • Xie, Z.1    Johansen, L.K.2    Gustafson, A.M.3
  • 225
    • 80052996141 scopus 로고    scopus 로고
    • Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants
    • Yang JS, Lai EC. (2011). Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants. Mol Cell 43: 892-903.
    • (2011) Mol Cell , vol.43 , pp. 892-903
    • Yang, J.S.1    Lai, E.C.2
  • 226
    • 33748363713 scopus 로고    scopus 로고
    • L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells
    • Yang N, Kazazian JR HH. (2006). L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells. Nat Struct Mol Biol 13:763-71.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 763-771
    • Yang, N.1    Kazazian, J.R.H.H.2
  • 227
    • 77953096072 scopus 로고    scopus 로고
    • Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
    • Yap KL, Li S, Munoz-Cabello AM, et al. (2010). Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell 38: 662-74.
    • (2010) Mol Cell , vol.38 , pp. 662-674
    • Yap, K.L.1    Li, S.2    Munoz-Cabello, A.M.3
  • 228
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi R, Qin Y, Macara IG, Cullen BR. (2003). Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17:3011-16.
    • (2003) Genes Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 229
    • 24944491201 scopus 로고    scopus 로고
    • A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis
    • Yoshikawa M, Peragine A, Park MY, Poethig RS. (2005). A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis. Genes Dev 19: 2164-75.
    • (2005) Genes Dev , vol.19 , pp. 2164-2175
    • Yoshikawa, M.1    Peragine, A.2    Park, M.Y.3    Poethig, R.S.4
  • 230
    • 84865688581 scopus 로고    scopus 로고
    • Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression
    • Yu D, Pendergraff H, Liu J, et al. (2012). Single-stranded RNAs use RNAi to potently and allele-selectively inhibit mutant huntingtin expression. Cell 150:895-908.
    • (2012) Cell , vol.150 , pp. 895-908
    • Yu, D.1    Pendergraff, H.2    Liu, J.3
  • 231
    • 70349147889 scopus 로고    scopus 로고
    • Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform
    • Zhou R, Czech B, Brennecke J, et al. (2009). Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. RNA 15: 1886-95.
    • (2009) RNA , vol.15 , pp. 1886-1895
    • Zhou, R.1    Czech, B.2    Brennecke, J.3
  • 232
    • 55949117057 scopus 로고    scopus 로고
    • Comparative analysis of argonaute-dependent small RNA pathways in Drosophila
    • Zhou R, Hotta I, Denli AM, et al. (2008). Comparative analysis of argonaute-dependent small RNA pathways in Drosophila. Mol Cell 32:592-9.
    • (2008) Mol Cell , vol.32 , pp. 592-599
    • Zhou, R.1    Hotta, I.2    Denli, A.M.3
  • 233
    • 0035883743 scopus 로고    scopus 로고
    • Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes
    • Zwart R, Sleutels F, Wutz A, et al. (2001). Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes. Genes Dev 15:2361-6.
    • (2001) Genes Dev , vol.15 , pp. 2361-2366
    • Zwart, R.1    Sleutels, F.2    Wutz, A.3


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