-
1
-
-
60149088848
-
Origins and mechanisms of miRNAs and siRNAs
-
Carthew, R.W. & Sontheimer, E.J. Origins and mechanisms of miRNAs and siRNAs. Cell 136, 642-655 (2009).
-
(2009)
Cell
, vol.136
, pp. 642-655
-
-
Carthew, R.W.1
Sontheimer, E.J.2
-
2
-
-
36249019204
-
Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes
-
Liu, X. et al. Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes. RNA 13, 2324-2329 (2007).
-
(2007)
RNA
, vol.13
, pp. 2324-2329
-
-
Liu, X.1
-
3
-
-
0141868916
-
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway
-
Liu, Q. et al. R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway. Science 301, 1921-1925 (2003).
-
(2003)
Science
, vol.301
, pp. 1921-1925
-
-
Liu, Q.1
-
4
-
-
1842766252
-
A Dicer-2- dependent 80S complex cleaves targeted mRNAs during RNAi in Drosophila
-
Pham, J.W., Pellino, J.L., Lee, Y.S., Carthew, R.W. & Sontheimer, E.J. A Dicer-2- dependent 80S complex cleaves targeted mRNAs during RNAi in Drosophila. Cell 117, 83-94 (2004).
-
(2004)
Cell
, vol.117
, pp. 83-94
-
-
Pham, J.W.1
Pellino, J.L.2
Lee, Y.S.3
Carthew, R.W.4
Sontheimer, E.J.5
-
5
-
-
44349174824
-
Endogenous RNA interference provides a somatic defense against Drosophila transposons
-
Chung, WJ., Okamura, K., Martin, R. & Lai, E.C. Endogenous RNA interference provides a somatic defense against Drosophila transposons. Curr. Biol. 18, 795-802 (2008).
-
(2008)
Curr. Biol.
, vol.18
, pp. 795-802
-
-
Chung, W.J.1
Okamura, K.2
Martin, R.3
Lai, E.C.4
-
6
-
-
44349104241
-
An endogenous small interfering RNA pathway in Drosophila
-
Czech, B. et al. An endogenous small interfering RNA pathway in Drosophila. Nature 453, 798-802 (2008).
-
(2008)
Nature
, vol.453
, pp. 798-802
-
-
Czech, B.1
-
7
-
-
44449096738
-
Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells
-
Ghildiyal, M. et al. Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells. Science 320, 1077-1081 (2008).
-
(2008)
Science
, vol.320
, pp. 1077-1081
-
-
Ghildiyal, M.1
-
8
-
-
44349103084
-
Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells
-
Kawamura, Y. et al. Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells. Nature 453, 793-797 (2008).
-
(2008)
Nature
, vol.453
, pp. 793-797
-
-
Kawamura, Y.1
-
9
-
-
44349101881
-
Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster
-
Okamura, K., Balla, S., Martin, R., Liu, N. & Lai, E.C. Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster. Nat. Struct. Mol. Biol. 15, 581-590 (2008).
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 581-590
-
-
Okamura, K.1
Balla, S.2
Martin, R.3
Liu, N.4
Lai, E.C.5
-
10
-
-
44349084754
-
The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs
-
Okamura, K. et al. The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature 453, 803-806 (2008).
-
(2008)
Nature
, vol.453
, pp. 803-806
-
-
Okamura, K.1
-
11
-
-
44349159416
-
Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes
-
Tam, O.H. et al. Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes. Nature 453, 534-538 (2008).
-
(2008)
Nature
, vol.453
, pp. 534-538
-
-
Tam, O.H.1
-
12
-
-
44349130233
-
Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes
-
Watanabe, T. et al. Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature 453, 539-543 (2008).
-
(2008)
Nature
, vol.453
, pp. 539-543
-
-
Watanabe, T.1
-
13
-
-
0037737975
-
MicroRNAs and other tiny endogenous RNAs in C. Elegans
-
Ambros, V., Lee, R.C., Lavanway, A., Williams, P.T. & Jewell, D. MicroRNAs and other tiny endogenous RNAs in C. elegans. Curr. Biol. 13, 807-818 (2003).
-
(2003)
Curr. Biol.
, vol.13
, pp. 807-818
-
-
Ambros, V.1
Lee, R.C.2
Lavanway, A.3
Williams, P.T.4
Jewell, D.5
-
14
-
-
33846527241
-
Distinct populations of primary and secondary effectors during RNAi in C. Elegans
-
Pak, J. & Fire, A. Distinct populations of primary and secondary effectors during RNAi in C. elegans. Science 315, 241-244 (2007).
-
(2007)
Science
, vol.315
, pp. 241-244
-
-
Pak, J.1
Fire, A.2
-
15
-
-
58449134534
-
Small silencing RNAs: An expanding universe
-
Ghildiyal, M. & Zamore, P.D. Small silencing RNAs: an expanding universe. Nat. Rev. Genet. 10, 94-108 (2009).
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 94-108
-
-
Ghildiyal, M.1
Zamore, P.D.2
-
16
-
-
50149095122
-
Endogenous small interfering RNAs in animals
-
Okamura, K. & Lai, E.C. Endogenous small interfering RNAs in animals. Nat. Rev. Mol. Cell Biol. 9, 673-678 (2008).
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 673-678
-
-
Okamura, K.1
Lai, E.C.2
-
17
-
-
70349147889
-
Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform
-
Zhou, R. et al. Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. RNA 15, 1886-1895 (2009).
-
(2009)
RNA
, vol.15
, pp. 1886-1895
-
-
Zhou, R.1
-
18
-
-
33746581711
-
Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes
-
Liu, X., Jiang, F., Kalidas, S., Smith, D. & Liu, Q. Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes. RNA 12, 1514-1520 (2006).
-
(2006)
RNA
, vol.12
, pp. 1514-1520
-
-
Liu, X.1
Jiang, F.2
Kalidas, S.3
Smith, D.4
Liu, Q.5
-
19
-
-
8844271740
-
A protein sensor for siRNA asymmetry
-
Tomari, Y., Matranga, C., Haley, B., Martinez, N. & Zamore, P.D. A protein sensor for siRNA asymmetry. Science 306, 1377-1380 (2004).
-
(2004)
Science
, vol.306
, pp. 1377-1380
-
-
Tomari, Y.1
Matranga, C.2
Haley, B.3
Martinez, N.4
Zamore, P.D.5
-
20
-
-
33645979325
-
RNA interference directs innate immunity against viruses in adult Drosophila
-
Wang, X.H. et al. RNA interference directs innate immunity against viruses in adult Drosophila. Science 312, 452-454 (2006).
-
(2006)
Science
, vol.312
, pp. 452-454
-
-
Wang, X.H.1
-
21
-
-
33746608192
-
The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing
-
Saleh, M.C. et al. The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing. Nat. Cell Biol. 8, 793-802 (2006).
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 793-802
-
-
Saleh, M.C.1
-
22
-
-
33744910636
-
Double-stranded RNA is internalized by scavenger receptor- mediated endocytosis in Drosophila S2 cells
-
Ulvila, J. et al. Double-stranded RNA is internalized by scavenger receptor- mediated endocytosis in Drosophila S2 cells. J. Biol. Chem. 281, 14370-14375 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 14370-14375
-
-
Ulvila, J.1
-
23
-
-
55949117057
-
Comparative analysis of Argonaute-dependent small RNA pathways in Drosophila
-
Zhou, R. et al. Comparative analysis of Argonaute-dependent small RNA pathways in Drosophila. Mol. Cell 32, 592-599 (2008).
-
(2008)
Mol. Cell
, vol.32
, pp. 592-599
-
-
Zhou, R.1
-
24
-
-
33747037802
-
A genomewide screen for components of the RNAi pathway in Drosophila cultured cells
-
Dorner, S. et al. A genomewide screen for components of the RNAi pathway in Drosophila cultured cells. Proc. Natl. Acad. Sci. USA 103, 11880-11885 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 11880-11885
-
-
Dorner, S.1
-
25
-
-
3142729150
-
Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
-
Okamura, K., Ishizuka, A., Siomi, H. & Siomi, M.C. Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev. 18, 1655-1666 (2004)
-
(2004)
Genes Dev
, vol.18
, pp. 1655-1666
-
-
Okamura, K.1
Ishizuka, A.2
Siomi, H.3
Siomi, M.C.4
-
26
-
-
1842816517
-
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
-
Lee, Y.S. et al. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117, 69-81 (2004).
-
(2004)
Cell
, vol.117
, pp. 69-81
-
-
Lee, Y.S.1
-
27
-
-
33947107476
-
The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells
-
Park, J.K., Liu, X., Strauss, T.J., McKearin, D.M. & Liu, Q. The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells. Curr. Biol. 17, 533-538 (2007).
-
(2007)
Curr. Biol.
, vol.17
, pp. 533-538
-
-
Park, J.K.1
Liu, X.2
Strauss, T.J.3
McKearin, D.M.4
Liu, Q.5
-
28
-
-
22744433240
-
Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein
-
Forstemann, K. et al. Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein. PLoS Biol. 3, e236 (2005).
-
(2005)
Plos Biol
, vol.3
, pp. e236
-
-
Forstemann, K.1
-
29
-
-
0036682990
-
RNAi is activated during Drosophila oocyte maturation in a manner dependent on Aubergine and spindle-E
-
Kennerdell, J.R., Yamaguchi, S. & Carthew, R.W. RNAi is activated during Drosophila oocyte maturation in a manner dependent on Aubergine and spindle-E. Genes Dev. 16, 1884-1889 (2002).
-
(2002)
Genes Dev
, vol.16
, pp. 1884-1889
-
-
Kennerdell, J.R.1
Yamaguchi, S.2
Carthew, R.W.3
-
30
-
-
27744477630
-
Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway
-
Pham, J.W. & Sontheimer, E.J. Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway. J. Biol. Chem. 280, 39278-39283 (2005).
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 39278-39283
-
-
Pham, J.W.1
Sontheimer, E.J.2
-
31
-
-
23044462450
-
Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila
-
Jiang, F. et al. Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila. Genes Dev. 19, 1674-1679 (2005).
-
(2005)
Genes Dev
, vol.19
, pp. 1674-1679
-
-
Jiang, F.1
-
32
-
-
34447291602
-
The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC
-
Horwich, M.D. et al. The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr. Biol. 17, 1265-1272 (2007).
-
(2007)
Curr. Biol.
, vol.17
, pp. 1265-1272
-
-
Horwich, M.D.1
-
33
-
-
23944493378
-
Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis
-
Li, J., Yang, Z., Yu, B., Liu, J. & Chen, X. Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis. Curr. Biol. 15, 1501-1507 (2005)
-
(2005)
Curr. Biol.
, vol.15
, pp. 1501-1507
-
-
Li, J.1
Yang, Z.2
Yu, B.3
Liu, J.4
Chen, X.5
-
34
-
-
0037229840
-
The Drosophila gene collection: Identification of putative full-length cDNAs for 70% of D. melanogaster genes
-
Stapleton, M. et al. The Drosophila gene collection: identification of putative full-length cDNAs for 70% of D. melanogaster genes. Genome Res. 12, 1294-1300 (2002).
-
(2002)
Genome Res
, vol.12
, pp. 1294-1300
-
-
Stapleton, M.1
-
35
-
-
60149098474
-
Small RNAs as guardians of the genome
-
Malone, C.D. & Hannon, G.J. Small RNAs as guardians of the genome. Cell 136, 656-668 (2009).
-
(2009)
Cell
, vol.136
, pp. 656-668
-
-
Malone, C.D.1
Hannon, G.J.2
-
36
-
-
0036847540
-
Ribonuclease activity and RNA binding of recombinant human Dicer
-
Provost, P. et al. Ribonuclease activity and RNA binding of recombinant human Dicer. EMBO J. 21, 5864-5874 (2002).
-
(2002)
EMBO J
, vol.21
, pp. 5864-5874
-
-
Provost, P.1
-
37
-
-
34447642555
-
Sorting of Drosophila small silencing RNAs
-
Tomari, Y., Du, T. & Zamore, P.D. Sorting of Drosophila small silencing RNAs. Cell 130, 299-308 (2007).
-
(2007)
Cell
, vol.130
, pp. 299-308
-
-
Tomari, Y.1
Du, T.2
Zamore, P.D.3
-
38
-
-
34547115237
-
Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA
-
Kok, K.H., Ng, M.H., Ching, Y.P. & Jin, D.Y. Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA. J. Biol. Chem. 282, 17649-17657 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 17649-17657
-
-
Kok, K.H.1
Ng, M.H.2
Ching, Y.P.3
Jin, D.Y.4
-
39
-
-
34548687914
-
Construction of small RNA cDNA libraries for deep sequencing
-
Lu, C., Meyers, B.C. & Green, P.J. Construction of small RNA cDNA libraries for deep sequencing. Methods 43, 110-117 (2007).
-
(2007)
Methods
, vol.43
, pp. 110-117
-
-
Lu, C.1
Meyers, B.C.2
Green, P.J.3
-
40
-
-
34250374820
-
Carbodiimide- mediated cross-linking of RNA to nylon membranes improves the detection of siRNA, miRNA and piRNA by northern blot
-
Pall, G.S., Codony-Servat, C., Byrne, J., Ritchie, L. & Hamilton, A. Carbodiimide- mediated cross-linking of RNA to nylon membranes improves the detection of siRNA, miRNA and piRNA by northern blot. Nucleic Acids Res. 35, e60 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
, pp. e60
-
-
Pall, G.S.1
Codony-Servat, C.2
Byrne, J.3
Ritchie, L.4
Hamilton, A.5
-
41
-
-
0033572660
-
Targeted mRNA degradation by double-stranded RNA in vitro
-
Tuschl, T., Zamore, P.D., Lehmann, R., Bartel, D.P. & Sharp, P.A. Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev. 13, 3191-3197 (1999).
-
(1999)
Genes Dev
, vol.13
, pp. 3191-3197
-
-
Tuschl, T.1
Zamore, P.D.2
Lehmann, R.3
Bartel, D.P.4
Sharp, P.A.5
-
42
-
-
65349094759
-
Computational and analytical framework for small RNA profiling by high-throughput sequencing
-
Fahlgren, N. et al. Computational and analytical framework for small RNA profiling by high-throughput sequencing. RNA 15, 992-1002 (2009).
-
(2009)
RNA
, vol.15
, pp. 992-1002
-
-
Fahlgren, N.1
|