Local RNA target structure influences siRNA efficacy: Systematic analysis of intentionally designed binding regions

Journal of Molecular Biology

Volumn 348, Issue 4, 2005, Pages 883-893

  Schubert, Steffen ^a   Grünweller, Arnold ^a,b   Erdmann, Volker A ^a   Kurreck, Jens ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

RNA interference; RNA structure; siRNA; siRNA efficacy; Small interfering RNA

Indexed keywords

MESSENGER RNA; SMALL INTERFERING RNA; VANILLOID RECEPTOR 1;

ARTICLE; BASE PAIRING; CONFORMATION; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; PRIORITY JOURNAL; REPORTER GENE; RNA INTERFERENCE; RNA SEQUENCE; RNA STRUCTURE; START CODON; THERMODYNAMICS;

EID: 17444412299     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.03.011     Document Type: Article

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