Local RNA target structure influences siRNA efficacy: A systematic global analysis

Journal of Molecular Biology

Volumn 348, Issue 4, 2005, Pages 871-881

  Overhoff, Marita ^a   Alken, Martina ^b   Far, Rosel Kretschmer Kazemi ^a   Lemaitre, Marc ^c   Lebleu, Bernard ^b   Sczakiel, Georg ^a   Robbins, Ian ^b  

^a UNIVERSITY OF LÜBECK   (Germany)

^b UNIVERSITÉ DE MONTPELLIER   (France)

^c EUROGENTEC S A   (Belgium)

Author keywords

RNA structure; siRNA, design; siRNA, mechanism

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; SMALL INTERFERING RNA; SURVIVIN;

ARTICLE; CELL CULTURE; DATA ANALYSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IC 50; INHIBITION KINETICS; PRIORITY JOURNAL; PRODUCTIVITY; PROTEIN SECONDARY STRUCTURE; PROTEIN TARGETING; RNA ANALYSIS; RNA STRUCTURE; STATISTICAL SIGNIFICANCE; STRUCTURE ANALYSIS;

EID: 17444365809     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.03.012     Document Type: Article

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