Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice

Nature Genetics

Volumn 37, Issue 7, 2005, Pages 750-755

  Wang, Yuxun ^a   Putnam, Christopher D ^b   Kane, Michael F ^b   Zhang, Weijia ^c   Edelmann, Lisa ^d   Russell, Robert ^a   Carrión, Danaise V ^c   Chin, Lynda ^e   Kucherlapati, Raju ^c   Kolodner, Richard D ^b   Edelmann, Winfried ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d NEW YORK UNIVERSITY   (United States)

^e DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; REPLICATION PROTEIN A; DNA BINDING PROTEIN; RPA1 PROTEIN, MOUSE;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CANCER; CANCER INHIBITION; CHROMOSOMAL INSTABILITY; CHROMOSOME ANALYSIS; CONTROLLED STUDY; DNA METABOLISM; DNA REPAIR; DNA STRAND BREAKAGE; FEMALE; GENE MUTATION; HISTOPATHOLOGY; HYBRIDIZATION; LYMPHATIC SYSTEM TUMOR; LYMPHOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; YEAST; ANIMAL; CELL CULTURE; EMBRYO DEATH; GENETICS; HEMATOPOIESIS; HETEROZYGOTE; HYPERPLASIA; KARYOTYPING; LYMPHOID TISSUE; METABOLISM; MISSENSE MUTATION; MOLECULAR GENETICS; MORTALITY; MOUSE MUTANT; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; TIME;

ANIMALIA;

ANEUPLOIDY; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; CHROMOSOMAL INSTABILITY; DNA REPAIR; DNA-BINDING PROTEINS; EMBRYO LOSS; FEMALE; HEMATOPOIESIS; HETEROZYGOTE; HYPERPLASIA; KARYOTYPING; LYMPHOID TISSUE; LYMPHOMA; MALE; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; MUTATION; MUTATION, MISSENSE; REPLICATION PROTEIN A; TIME FACTORS; YEASTS;

EID: 22844436867     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng1587     Document Type: Article

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