-
1
-
-
0036469913
-
The connection between transcription and genomic instability
-
Aguilera A. The connection between transcription and genomic instability. EMBO J. 2002, 21:195-201.
-
(2002)
EMBO J.
, vol.21
, pp. 195-201
-
-
Aguilera, A.1
-
2
-
-
39449096135
-
Genome instability: a mechanistic view of its causes and consequences
-
Aguilera A., Gómez-González B. Genome instability: a mechanistic view of its causes and consequences. Nat. Rev. Genet. 2008, 9:204-217.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 204-217
-
-
Aguilera, A.1
Gómez-González, B.2
-
3
-
-
83355169557
-
Two pathways for RNase E action in Escherichia coli in vivo and bypass of its essentiality in mutants defective for Rho-dependent transcription termination
-
Anupama K., Leela J.K., Gowrishankar J. Two pathways for RNase E action in Escherichia coli in vivo and bypass of its essentiality in mutants defective for Rho-dependent transcription termination. Mol. Microbiol. 2011, 82:1330-1348.
-
(2011)
Mol. Microbiol.
, vol.82
, pp. 1330-1348
-
-
Anupama, K.1
Leela, J.K.2
Gowrishankar, J.3
-
4
-
-
67449113551
-
Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae
-
Azvolinsky A., Giresi P.G., Lieb J.D., Zakian V.A. Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae. Mol. Cell 2009, 34:722-734.
-
(2009)
Mol. Cell
, vol.34
, pp. 722-734
-
-
Azvolinsky, A.1
Giresi, P.G.2
Lieb, J.D.3
Zakian, V.A.4
-
5
-
-
4744343661
-
RNase HI overproduction is required for efficient full-length RNA synthesis in the absence of topoisomerase I in Escherichia coli
-
Baaklini I., Hraiky C., Rallu F., Tse-Dinh Y.C., Drolet M. RNase HI overproduction is required for efficient full-length RNA synthesis in the absence of topoisomerase I in Escherichia coli. Mol. Microbiol. 2004, 54:198-211.
-
(2004)
Mol. Microbiol.
, vol.54
, pp. 198-211
-
-
Baaklini, I.1
Hraiky, C.2
Rallu, F.3
Tse-Dinh, Y.C.4
Drolet, M.5
-
6
-
-
0021489748
-
The initiation of DNA replication in the mitochondrial genome of yeast
-
Baldacci G., Chérif-Zahar B., Bernardi G. The initiation of DNA replication in the mitochondrial genome of yeast. EMBO J. 1984, 3:2115-2120.
-
(1984)
EMBO J.
, vol.3
, pp. 2115-2120
-
-
Baldacci, G.1
Chérif-Zahar, B.2
Bernardi, G.3
-
7
-
-
77955650378
-
Mechanisms and implications of transcription blockage by guanine-rich DNA sequences
-
Belotserkovskii B.P., Liu R., Tornaletti S., Krasilnikova M.M., Mirkin S.M., Hanawalt P.C. Mechanisms and implications of transcription blockage by guanine-rich DNA sequences. Proc. Natl. Acad. Sci. USA 2010, 107:12816-12821.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 12816-12821
-
-
Belotserkovskii, B.P.1
Liu, R.2
Tornaletti, S.3
Krasilnikova, M.M.4
Mirkin, S.M.5
Hanawalt, P.C.6
-
8
-
-
79960802984
-
The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores
-
Bermejo R., Capra T., Jossen R., Colosio A., Frattini C., Carotenuto W., Cocito A., Doksani Y., Klein H., Gómez-González B., et al. The replication checkpoint protects fork stability by releasing transcribed genes from nuclear pores. Cell 2011, 146:233-246.
-
(2011)
Cell
, vol.146
, pp. 233-246
-
-
Bermejo, R.1
Capra, T.2
Jossen, R.3
Colosio, A.4
Frattini, C.5
Carotenuto, W.6
Cocito, A.7
Doksani, Y.8
Klein, H.9
Gómez-González, B.10
-
9
-
-
75649142564
-
The helicases DinG, Rep and UvrD cooperate to promote replication across transcription units in vivo
-
Boubakri H., de Septenville A.L., Viguera E., Michel B. The helicases DinG, Rep and UvrD cooperate to promote replication across transcription units in vivo. EMBO J. 2010, 29:145-157.
-
(2010)
EMBO J.
, vol.29
, pp. 145-157
-
-
Boubakri, H.1
de Septenville, A.L.2
Viguera, E.3
Michel, B.4
-
10
-
-
34848908787
-
The yeast Pif1p DNA helicase preferentially unwinds RNA DNA substrates
-
Boulé J.B., Zakian V.A. The yeast Pif1p DNA helicase preferentially unwinds RNA DNA substrates. Nucleic Acids Res. 2007, 35:5809-5818.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 5809-5818
-
-
Boulé, J.B.1
Zakian, V.A.2
-
11
-
-
61349102407
-
Ribonuclease H: the enzymes in eukaryotes
-
Cerritelli S.M., Crouch R.J. Ribonuclease H: the enzymes in eukaryotes. FEBS J. 2009, 276:1494-1505.
-
(2009)
FEBS J.
, vol.276
, pp. 1494-1505
-
-
Cerritelli, S.M.1
Crouch, R.J.2
-
12
-
-
3142765336
-
Class-switch recombination: interplay of transcription, DNA deamination and DNA repair
-
Chaudhuri J., Alt F.W. Class-switch recombination: interplay of transcription, DNA deamination and DNA repair. Nat. Rev. Immunol. 2004, 4:541-552.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 541-552
-
-
Chaudhuri, J.1
Alt, F.W.2
-
13
-
-
84860187274
-
Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability
-
Chernikova S.B., Razorenova O.V., Higgins J.P., Sishc B.J., Nicolau M., Dorth J.A., Chernikova D.A., Kwok S., Brooks J.D., Bailey S.M., et al. Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability. Cancer Res. 2012, 72:2111-2119.
-
(2012)
Cancer Res.
, vol.72
, pp. 2111-2119
-
-
Chernikova, S.B.1
Razorenova, O.V.2
Higgins, J.P.3
Sishc, B.J.4
Nicolau, M.5
Dorth, J.A.6
Chernikova, D.A.7
Kwok, S.8
Brooks, J.D.9
Bailey, S.M.10
-
14
-
-
79952273242
-
Break-induced replication is highly inaccurate
-
Deem A., Keszthelyi A., Blackgrove T., Vayl A., Coffey B., Mathur R., Chabes A., Malkova A. Break-induced replication is highly inaccurate. PLoS Biol. 2011, 9:e1000594.
-
(2011)
PLoS Biol.
, vol.9
-
-
Deem, A.1
Keszthelyi, A.2
Blackgrove, T.3
Vayl, A.4
Coffey, B.5
Mathur, R.6
Chabes, A.7
Malkova, A.8
-
15
-
-
33645052194
-
Growth inhibition mediated by excess negative supercoiling: the interplay between transcription elongation, R-loop formation and DNA topology
-
Drolet M. Growth inhibition mediated by excess negative supercoiling: the interplay between transcription elongation, R-loop formation and DNA topology. Mol. Microbiol. 2006, 59:723-730.
-
(2006)
Mol. Microbiol.
, vol.59
, pp. 723-730
-
-
Drolet, M.1
-
16
-
-
0028006543
-
Hypernegative supercoiling of the DNA template during transcription elongation in vitro
-
Drolet M., Bi X., Liu L.F. Hypernegative supercoiling of the DNA template during transcription elongation in vitro. J. Biol. Chem. 1994, 269:2068-2074.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2068-2074
-
-
Drolet, M.1
Bi, X.2
Liu, L.F.3
-
17
-
-
0028966185
-
Overexpression of RNase H partially complements the growth defect of an Escherichia coli delta topA mutant: R-loop formation is a major problem in the absence of DNA topoisomerase I
-
Drolet M., Phoenix P., Menzel R., Massé E., Liu L.F., Crouch R.J. Overexpression of RNase H partially complements the growth defect of an Escherichia coli delta topA mutant: R-loop formation is a major problem in the absence of DNA topoisomerase I. Proc. Natl. Acad. Sci. USA 1995, 92:3526-3530.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3526-3530
-
-
Drolet, M.1
Phoenix, P.2
Menzel, R.3
Massé, E.4
Liu, L.F.5
Crouch, R.J.6
-
18
-
-
3042785608
-
Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA
-
Duquette M.L., Handa P., Vincent J.A., Taylor A.F., Maizels N. Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNA. Genes Dev. 2004, 18:1618-1629.
-
(2004)
Genes Dev.
, vol.18
, pp. 1618-1629
-
-
Duquette, M.L.1
Handa, P.2
Vincent, J.A.3
Taylor, A.F.4
Maizels, N.5
-
19
-
-
34047271986
-
G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas
-
Duquette M.L., Huber M.D., Maizels N. G-rich proto-oncogenes are targeted for genomic instability in B-cell lymphomas. Cancer Res. 2007, 67:2586-2594.
-
(2007)
Cancer Res.
, vol.67
, pp. 2586-2594
-
-
Duquette, M.L.1
Huber, M.D.2
Maizels, N.3
-
20
-
-
80052008241
-
Linking RNA polymerase backtracking to genome instability in E. coli
-
Dutta D., Shatalin K., Epshtein V., Gottesman M.E., Nudler E. Linking RNA polymerase backtracking to genome instability in E. coli. Cell 2011, 146:533-543.
-
(2011)
Cell
, vol.146
, pp. 533-543
-
-
Dutta, D.1
Shatalin, K.2
Epshtein, V.3
Gottesman, M.E.4
Nudler, E.5
-
21
-
-
77954841539
-
Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis
-
El Hage A., French S.L., Beyer A.L., Tollervey D. Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis. Genes Dev. 2010, 24:1546-1558.
-
(2010)
Genes Dev.
, vol.24
, pp. 1546-1558
-
-
El Hage, A.1
French, S.L.2
Beyer, A.L.3
Tollervey, D.4
-
22
-
-
80053645721
-
R-loop-mediated genomic instability is caused by impairment of replication fork progression
-
Gan W., Guan Z., Liu J., Gui T., Shen K., Manley J.L., Li X. R-loop-mediated genomic instability is caused by impairment of replication fork progression. Genes Dev. 2011, 25:2041-2056.
-
(2011)
Genes Dev.
, vol.25
, pp. 2041-2056
-
-
Gan, W.1
Guan, Z.2
Liu, J.3
Gui, T.4
Shen, K.5
Manley, J.L.6
Li, X.7
-
23
-
-
84859087611
-
R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters
-
Ginno P.A., Lott P.L., Christensen H.C., Korf I., Chédin F. R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters. Mol. Cell 2012, 45:814-825.
-
(2012)
Mol. Cell
, vol.45
, pp. 814-825
-
-
Ginno, P.A.1
Lott, P.L.2
Christensen, H.C.3
Korf, I.4
Chédin, F.5
-
24
-
-
34347218988
-
Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex
-
Gómez-González B., Aguilera A. Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex. Proc. Natl. Acad. Sci. USA 2007, 104:8409-8414.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 8409-8414
-
-
Gómez-González, B.1
Aguilera, A.2
-
25
-
-
70349335582
-
The S-phase checkpoint is required to respond to R-loops accumulated in THO mutants
-
Gómez-González B., Felipe-Abrio I., Aguilera A. The S-phase checkpoint is required to respond to R-loops accumulated in THO mutants. Mol. Cell. Biol. 2009, 29:5203-5213.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 5203-5213
-
-
Gómez-González, B.1
Felipe-Abrio, I.2
Aguilera, A.3
-
26
-
-
79961031438
-
Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles
-
Gómez-González B., García-Rubio M., Bermejo R., Gaillard H., Shirahige K., Marín A., Foiani M., Aguilera A. Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles. EMBO J. 2011, 30:3106-3119.
-
(2011)
EMBO J.
, vol.30
, pp. 3106-3119
-
-
Gómez-González, B.1
García-Rubio, M.2
Bermejo, R.3
Gaillard, H.4
Shirahige, K.5
Marín, A.6
Foiani, M.7
Aguilera, A.8
-
27
-
-
57349185689
-
The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability
-
González-Aguilera C., Tous C., Gómez-González B., Huertas P., Luna R., Aguilera A. The THP1-SAC3-SUS1-CDC31 complex works in transcription elongation-mRNA export preventing RNA-mediated genome instability. Mol. Biol. Cell 2008, 19:4310-4318.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4310-4318
-
-
González-Aguilera, C.1
Tous, C.2
Gómez-González, B.3
Huertas, P.4
Luna, R.5
Aguilera, A.6
-
28
-
-
37549026516
-
Transcription-associated recombination is dependent on replication in Mammalian cells
-
Gottipati P., Cassel T.N., Savolainen L., Helleday T. Transcription-associated recombination is dependent on replication in Mammalian cells. Mol. Cell. Biol. 2008, 28:154-164.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 154-164
-
-
Gottipati, P.1
Cassel, T.N.2
Savolainen, L.3
Helleday, T.4
-
29
-
-
7644223774
-
Why is transcription coupled to translation in bacteria?
-
Gowrishankar J., Harinarayanan R. Why is transcription coupled to translation in bacteria?. Mol. Microbiol. 2004, 54:598-603.
-
(2004)
Mol. Microbiol.
, vol.54
, pp. 598-603
-
-
Gowrishankar, J.1
Harinarayanan, R.2
-
30
-
-
34548775695
-
A persistent RNA.DNA hybrid formed by transcription of the Friedreich ataxia triplet repeat in live bacteria, and by T7 RNAP in vitro
-
Grabczyk E., Mancuso M., Sammarco M.C. A persistent RNA.DNA hybrid formed by transcription of the Friedreich ataxia triplet repeat in live bacteria, and by T7 RNAP in vitro. Nucleic Acids Res. 2007, 35:5351-5359.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 5351-5359
-
-
Grabczyk, E.1
Mancuso, M.2
Sammarco, M.C.3
-
31
-
-
84255198334
-
Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes
-
Helmrich A., Ballarino M., Tora L. Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes. Mol. Cell 2011, 44:966-977.
-
(2011)
Mol. Cell
, vol.44
, pp. 966-977
-
-
Helmrich, A.1
Ballarino, M.2
Tora, L.3
-
32
-
-
0029026201
-
Escherichia coli RecG and RecA proteins in R-loop formation
-
Hong X., Cadwell G.W., Kogoma T. Escherichia coli RecG and RecA proteins in R-loop formation. EMBO J. 1995, 14:2385-2392.
-
(1995)
EMBO J.
, vol.14
, pp. 2385-2392
-
-
Hong, X.1
Cadwell, G.W.2
Kogoma, T.3
-
33
-
-
78650849800
-
DNA-RNA hybrids contribute to the replication dependent genomic instability induced by Omcg1 deficiency
-
Houlard M., Artus J., Léguillier T., Vandormael-Pournin S., Cohen-Tannoudji M. DNA-RNA hybrids contribute to the replication dependent genomic instability induced by Omcg1 deficiency. Cell Cycle 2011, 10:108-117.
-
(2011)
Cell Cycle
, vol.10
, pp. 108-117
-
-
Houlard, M.1
Artus, J.2
Léguillier, T.3
Vandormael-Pournin, S.4
Cohen-Tannoudji, M.5
-
34
-
-
80052698473
-
Helicase dissociation and annealing of RNA-DNA hybrids by Escherichia coli Cas3 protein
-
Howard J.A., Delmas S., Ivančić-Baće I., Bolt E.L. Helicase dissociation and annealing of RNA-DNA hybrids by Escherichia coli Cas3 protein. Biochem. J. 2011, 439:85-95.
-
(2011)
Biochem. J.
, vol.439
, pp. 85-95
-
-
Howard, J.A.1
Delmas, S.2
Ivančić-Baće, I.3
Bolt, E.L.4
-
35
-
-
0141819093
-
Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination
-
Huertas P., Aguilera A. Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination. Mol. Cell 2003, 12:711-721.
-
(2003)
Mol. Cell
, vol.12
, pp. 711-721
-
-
Huertas, P.1
Aguilera, A.2
-
36
-
-
56049121180
-
G-quadruplexes: the beginning and end of UTRs
-
Huppert J.L., Bugaut A., Kumari S., Balasubramanian S. G-quadruplexes: the beginning and end of UTRs. Nucleic Acids Res. 2008, 36:6260-6268.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 6260-6268
-
-
Huppert, J.L.1
Bugaut, A.2
Kumari, S.3
Balasubramanian, S.4
-
37
-
-
1842391776
-
Formation of an RNA primer for initiation of replication of ColE1 DNA by ribonuclease H
-
Itoh T., Tomizawa J. Formation of an RNA primer for initiation of replication of ColE1 DNA by ribonuclease H. Proc. Natl. Acad. Sci. USA 1980, 77:2450-2454.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 2450-2454
-
-
Itoh, T.1
Tomizawa, J.2
-
38
-
-
0033517855
-
The sen1(+) gene of Schizosaccharomyces pombe, a homologue of budding yeast SEN1, encodes an RNA and DNA helicase
-
Kim H.D., Choe J., Seo Y.S. The sen1(+) gene of Schizosaccharomyces pombe, a homologue of budding yeast SEN1, encodes an RNA and DNA helicase. Biochemistry 1999, 38:14697-14710.
-
(1999)
Biochemistry
, vol.38
, pp. 14697-14710
-
-
Kim, H.D.1
Choe, J.2
Seo, Y.S.3
-
39
-
-
80051823466
-
Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast
-
Kim N., Jinks-Robertson S. Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast. DNA Repair (Amst.) 2011, 10:953-960.
-
(2011)
DNA Repair (Amst.)
, vol.10
, pp. 953-960
-
-
Kim, N.1
Jinks-Robertson, S.2
-
40
-
-
79953707188
-
Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeast
-
Kobayashi T. Regulation of ribosomal RNA gene copy number and its role in modulating genome integrity and evolutionary adaptability in yeast. Cell. Mol. Life Sci. 2011, 68:1395-1403.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 1395-1403
-
-
Kobayashi, T.1
-
41
-
-
0030737725
-
Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription
-
Kogoma T. Stable DNA replication: interplay between DNA replication, homologous recombination, and transcription. Microbiol. Mol. Biol. Rev. 1997, 61:212-238.
-
(1997)
Microbiol. Mol. Biol. Rev.
, vol.61
, pp. 212-238
-
-
Kogoma, T.1
-
42
-
-
78649531872
-
Initiation of bacteriophage T4 DNA replication and replication fork dynamics: a review in the Virology Journal series on bacteriophage T4 and its relatives
-
Kreuzer K.N., Brister J.R. Initiation of bacteriophage T4 DNA replication and replication fork dynamics: a review in the Virology Journal series on bacteriophage T4 and its relatives. Virol. J. 2010, 7:358.
-
(2010)
Virol. J.
, vol.7
, pp. 358
-
-
Kreuzer, K.N.1
Brister, J.R.2
-
43
-
-
23744455164
-
Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability
-
Li X., Manley J.L. Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability. Cell 2005, 122:365-378.
-
(2005)
Cell
, vol.122
, pp. 365-378
-
-
Li, X.1
Manley, J.L.2
-
44
-
-
76249098186
-
R loops stimulate genetic instability of CTG.CAG repeats
-
Lin Y., Dent S.Y., Wilson J.H., Wells R.D., Napierala M. R loops stimulate genetic instability of CTG.CAG repeats. Proc. Natl. Acad. Sci. USA 2010, 107:692-697.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 692-697
-
-
Lin, Y.1
Dent, S.Y.2
Wilson, J.H.3
Wells, R.D.4
Napierala, M.5
-
45
-
-
13944259332
-
Genetic network interactions among replication, repair and nuclear pore deficiencies in yeast
-
Loeillet S., Palancade B., Cartron M., Thierry A., Richard G.F., Dujon B., Doye V., Nicolas A. Genetic network interactions among replication, repair and nuclear pore deficiencies in yeast. DNA Repair (Amst.) 2005, 4:459-468.
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 459-468
-
-
Loeillet, S.1
Palancade, B.2
Cartron, M.3
Thierry, A.4
Richard, G.F.5
Dujon, B.6
Doye, V.7
Nicolas, A.8
-
46
-
-
80053611613
-
G-quadruplex-induced instability during leading-strand replication
-
Lopes J., Piazza A., Bermejo R., Kriegsman B., Colosio A., Teulade-Fichou M.P., Foiani M., Nicolas A. G-quadruplex-induced instability during leading-strand replication. EMBO J. 2011, 30:4033-4046.
-
(2011)
EMBO J.
, vol.30
, pp. 4033-4046
-
-
Lopes, J.1
Piazza, A.2
Bermejo, R.3
Kriegsman, B.4
Colosio, A.5
Teulade-Fichou, M.P.6
Foiani, M.7
Nicolas, A.8
-
47
-
-
55949106494
-
The Rat1p 5' to 3' exonuclease degrades telomeric repeat-containing RNA and promotes telomere elongation in Saccharomyces cerevisiae
-
Luke B., Panza A., Redon S., Iglesias N., Li Z., Lingner J. The Rat1p 5' to 3' exonuclease degrades telomeric repeat-containing RNA and promotes telomere elongation in Saccharomyces cerevisiae. Mol. Cell 2008, 32:465-477.
-
(2008)
Mol. Cell
, vol.32
, pp. 465-477
-
-
Luke, B.1
Panza, A.2
Redon, S.3
Iglesias, N.4
Li, Z.5
Lingner, J.6
-
48
-
-
20444366920
-
Interdependence between transcription and mRNP processing and export, and its impact on genetic stability
-
Luna R., Jimeno S., Marín M., Huertas P., García-Rubio M., Aguilera A. Interdependence between transcription and mRNP processing and export, and its impact on genetic stability. Mol. Cell 2005, 18:711-722.
-
(2005)
Mol. Cell
, vol.18
, pp. 711-722
-
-
Luna, R.1
Jimeno, S.2
Marín, M.3
Huertas, P.4
García-Rubio, M.5
Aguilera, A.6
-
49
-
-
33947432388
-
Replication fork stalling at natural impediments
-
Mirkin E.V., Mirkin S.M. Replication fork stalling at natural impediments. Microbiol. Mol. Biol. Rev. 2007, 71:13-35.
-
(2007)
Microbiol. Mol. Biol. Rev.
, vol.71
, pp. 13-35
-
-
Mirkin, E.V.1
Mirkin, S.M.2
-
50
-
-
78650727733
-
Yeast Sen1 helicase protects the genome from transcription-associated instability
-
Mischo H.E., Gómez-González B., Grzechnik P., Rondón A.G., Wei W., Steinmetz L., Aguilera A., Proudfoot N.J. Yeast Sen1 helicase protects the genome from transcription-associated instability. Mol. Cell 2011, 41:21-32.
-
(2011)
Mol. Cell
, vol.41
, pp. 21-32
-
-
Mischo, H.E.1
Gómez-González, B.2
Grzechnik, P.3
Rondón, A.G.4
Wei, W.5
Steinmetz, L.6
Aguilera, A.7
Proudfoot, N.J.8
-
51
-
-
84857237196
-
DNA-RNA hybrid formation mediates RNAi-directed heterochromatin formation
-
Nakama M., Kawakami K., Kajitani T., Urano T., Murakami Y. DNA-RNA hybrid formation mediates RNAi-directed heterochromatin formation. Genes Cells 2012, 17:218-233.
-
(2012)
Genes Cells
, vol.17
, pp. 218-233
-
-
Nakama, M.1
Kawakami, K.2
Kajitani, T.3
Urano, T.4
Murakami, Y.5
-
52
-
-
79957556530
-
DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase
-
Paeschke K., Capra J.A., Zakian V.A. DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase. Cell 2011, 145:678-691.
-
(2011)
Cell
, vol.145
, pp. 678-691
-
-
Paeschke, K.1
Capra, J.A.2
Zakian, V.A.3
-
53
-
-
34547726640
-
Nucleoporins prevent DNA damage accumulation by modulating Ulp1-dependent sumoylation processes
-
Palancade B., Liu X., Garcia-Rubio M., Aguilera A., Zhao X., Doye V. Nucleoporins prevent DNA damage accumulation by modulating Ulp1-dependent sumoylation processes. Mol. Biol. Cell 2007, 18:2912-2923.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 2912-2923
-
-
Palancade, B.1
Liu, X.2
Garcia-Rubio, M.3
Aguilera, A.4
Zhao, X.5
Doye, V.6
-
54
-
-
67651119997
-
A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability
-
Paulsen R.D., Soni D.V., Wollman R., Hahn A.T., Yee M.C., Guan A., Hesley J.A., Miller S.C., Cromwell E.F., Solow-Cordero D.E., et al. A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability. Mol. Cell 2009, 35:228-239.
-
(2009)
Mol. Cell
, vol.35
, pp. 228-239
-
-
Paulsen, R.D.1
Soni, D.V.2
Wollman, R.3
Hahn, A.T.4
Yee, M.C.5
Guan, A.6
Hesley, J.A.7
Miller, S.C.8
Cromwell, E.F.9
Solow-Cordero, D.E.10
-
56
-
-
0037019315
-
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
-
Petersen-Mahrt S.K., Harris R.S., Neuberger M.S. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 2002, 418:99-103.
-
(2002)
Nature
, vol.418
, pp. 99-103
-
-
Petersen-Mahrt, S.K.1
Harris, R.S.2
Neuberger, M.S.3
-
57
-
-
77950473394
-
Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid
-
Pohjoismäki J.L., Holmes J.B., Wood S.R., Yang M.Y., Yasukawa T., Reyes A., Bailey L.J., Cluett T.J., Goffart S., Willcox S., et al. Mammalian mitochondrial DNA replication intermediates are essentially duplex but contain extensive tracts of RNA/DNA hybrid. J. Mol. Biol. 2010, 397:1144-1155.
-
(2010)
J. Mol. Biol.
, vol.397
, pp. 1144-1155
-
-
Pohjoismäki, J.L.1
Holmes, J.B.2
Wood, S.R.3
Yang, M.Y.4
Yasukawa, T.5
Reyes, A.6
Bailey, L.J.7
Cluett, T.J.8
Goffart, S.9
Willcox, S.10
-
58
-
-
17144426028
-
Impairment of replication fork progression mediates RNA polII transcription-associated recombination
-
Prado F., Aguilera A. Impairment of replication fork progression mediates RNA polII transcription-associated recombination. EMBO J. 2005, 24:1267-1276.
-
(2005)
EMBO J.
, vol.24
, pp. 1267-1276
-
-
Prado, F.1
Aguilera, A.2
-
59
-
-
80052447253
-
Ending the message: poly(A) signals then and now
-
Proudfoot N.J. Ending the message: poly(A) signals then and now. Genes Dev. 2011, 25:1770-1782.
-
(2011)
Genes Dev.
, vol.25
, pp. 1770-1782
-
-
Proudfoot, N.J.1
-
60
-
-
4644257592
-
AID is required for c-myc/IgH chromosome translocations in vivo
-
Ramiro A.R., Jankovic M., Eisenreich T., Difilippantonio S., Chen-Kiang S., Muramatsu M., Honjo T., Nussenzweig A., Nussenzweig M.C. AID is required for c-myc/IgH chromosome translocations in vivo. Cell 2004, 118:431-438.
-
(2004)
Cell
, vol.118
, pp. 431-438
-
-
Ramiro, A.R.1
Jankovic, M.2
Eisenreich, T.3
Difilippantonio, S.4
Chen-Kiang, S.5
Muramatsu, M.6
Honjo, T.7
Nussenzweig, A.8
Nussenzweig, M.C.9
-
61
-
-
0025225502
-
Induction of RNA-stabilized DNA conformers by transcription of an immunoglobulin switch region
-
Reaban M.E., Griffin J.A. Induction of RNA-stabilized DNA conformers by transcription of an immunoglobulin switch region. Nature 1990, 348:342-344.
-
(1990)
Nature
, vol.348
, pp. 342-344
-
-
Reaban, M.E.1
Griffin, J.A.2
-
62
-
-
78651061861
-
Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats
-
Reddy K., Tam M., Bowater R.P., Barber M., Tomlinson M., Nichol Edamura K., Wang Y.H., Pearson C.E. Determinants of R-loop formation at convergent bidirectionally transcribed trinucleotide repeats. Nucleic Acids Res. 2011, 39:1749-1762.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 1749-1762
-
-
Reddy, K.1
Tam, M.2
Bowater, R.P.3
Barber, M.4
Tomlinson, M.5
Nichol Edamura, K.6
Wang, Y.H.7
Pearson, C.E.8
-
63
-
-
57149146036
-
AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations
-
Robbiani D.F., Bothmer A., Callen E., Reina-San-Martin B., Dorsett Y., Difilippantonio S., Bolland D.J., Chen H.T., Corcoran A.E., Nussenzweig A., Nussenzweig M.C. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell 2008, 135:1028-1038.
-
(2008)
Cell
, vol.135
, pp. 1028-1038
-
-
Robbiani, D.F.1
Bothmer, A.2
Callen, E.3
Reina-San-Martin, B.4
Dorsett, Y.5
Difilippantonio, S.6
Bolland, D.J.7
Chen, H.T.8
Corcoran, A.E.9
Nussenzweig, A.10
Nussenzweig, M.C.11
-
64
-
-
0027089978
-
Stability and properties of double and triple helices: dramatic effects of RNA or DNA backbone composition
-
Roberts R.W., Crothers D.M. Stability and properties of double and triple helices: dramatic effects of RNA or DNA backbone composition. Science 1992, 258:1463-1466.
-
(1992)
Science
, vol.258
, pp. 1463-1466
-
-
Roberts, R.W.1
Crothers, D.M.2
-
65
-
-
84857163904
-
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes
-
Rodriguez R., Miller K.M., Forment J.V., Bradshaw C.R., Nikan M., Britton S., Oelschlaegel T., Xhemalce B., Balasubramanian S., Jackson S.P. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes. Nat. Chem. Biol. 2012, 8:301-310.
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 301-310
-
-
Rodriguez, R.1
Miller, K.M.2
Forment, J.V.3
Bradshaw, C.R.4
Nikan, M.5
Britton, S.6
Oelschlaegel, T.7
Xhemalce, B.8
Balasubramanian, S.9
Jackson, S.P.10
-
66
-
-
77955664901
-
The interface between transcription and mRNP export: from THO to THSC/TREX-2
-
Rondón A.G., Jimeno S., Aguilera A. The interface between transcription and mRNP export: from THO to THSC/TREX-2. Biochim. Biophys. Acta 2010, 1799:533-538.
-
(2010)
Biochim. Biophys. Acta
, vol.1799
, pp. 533-538
-
-
Rondón, A.G.1
Jimeno, S.2
Aguilera, A.3
-
67
-
-
66349101604
-
G clustering is important for the initiation of transcription-induced R-loops in vitro, whereas high G density without clustering is sufficient thereafter
-
Roy D., Lieber M.R. G clustering is important for the initiation of transcription-induced R-loops in vitro, whereas high G density without clustering is sufficient thereafter. Mol. Cell. Biol. 2009, 29:3124-3133.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 3124-3133
-
-
Roy, D.1
Lieber, M.R.2
-
68
-
-
73649101345
-
Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site
-
Roy D., Zhang Z., Lu Z., Hsieh C.L., Lieber M.R. Competition between the RNA transcript and the nontemplate DNA strand during R-loop formation in vitro: a nick can serve as a strong R-loop initiation site. Mol. Cell. Biol. 2010, 30:146-159.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 146-159
-
-
Roy, D.1
Zhang, Z.2
Lu, Z.3
Hsieh, C.L.4
Lieber, M.R.5
-
69
-
-
79952266545
-
AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants
-
Ruiz J.F., Gómez-González B., Aguilera A. AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants. PLoS Genet. 2011, 7:e1002009.
-
(2011)
PLoS Genet.
, vol.7
-
-
Ruiz, J.F.1
Gómez-González, B.2
Aguilera, A.3
-
70
-
-
45849138859
-
Recognition of the unique structure of DNA:RNA hybrids
-
Shaw N.N., Arya D.P. Recognition of the unique structure of DNA:RNA hybrids. Biochimie 2008, 90:1026-1039.
-
(2008)
Biochimie
, vol.90
, pp. 1026-1039
-
-
Shaw, N.N.1
Arya, D.P.2
-
71
-
-
58149166729
-
Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway
-
Sikdar N., Banerjee S., Zhang H., Smith S., Myung K. Spt2p defines a new transcription-dependent gross chromosomal rearrangement pathway. PLoS Genet. 2008, 4:e1000290.
-
(2008)
PLoS Genet.
, vol.4
-
-
Sikdar, N.1
Banerjee, S.2
Zhang, H.3
Smith, S.4
Myung, K.5
-
72
-
-
79959345878
-
Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination
-
Skourti-Stathaki K., Proudfoot N.J., Gromak N. Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination. Mol. Cell 2011, 42:794-805.
-
(2011)
Mol. Cell
, vol.42
, pp. 794-805
-
-
Skourti-Stathaki, K.1
Proudfoot, N.J.2
Gromak, N.3
-
73
-
-
68249083044
-
Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks
-
Sordet O., Redon C.E., Guirouilh-Barbat J., Smith S., Solier S., Douarre C., Conti C., Nakamura A.J., Das B.B., Nicolas E., et al. Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks. EMBO Rep. 2009, 10:887-893.
-
(2009)
EMBO Rep.
, vol.10
, pp. 887-893
-
-
Sordet, O.1
Redon, C.E.2
Guirouilh-Barbat, J.3
Smith, S.4
Solier, S.5
Douarre, C.6
Conti, C.7
Nakamura, A.J.8
Das, B.B.9
Nicolas, E.10
-
74
-
-
84856253456
-
R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants
-
Stirling P.C., Chan Y.A., Minaker S.W., Aristizabal M.J., Barrett I., Sipahimalani P., Kobor M.S., Hieter P. R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants. Genes Dev. 2012, 26:163-175.
-
(2012)
Genes Dev.
, vol.26
, pp. 163-175
-
-
Stirling, P.C.1
Chan, Y.A.2
Minaker, S.W.3
Aristizabal, M.J.4
Barrett, I.5
Sipahimalani, P.6
Kobor, M.S.7
Hieter, P.8
-
75
-
-
70449522304
-
Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription
-
Tuduri S., Crabbé L., Conti C., Tourrière H., Holtgreve-Grez H., Jauch A., Pantesco V., De Vos J., Thomas A., Theillet C., et al. Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription. Nat. Cell Biol. 2009, 11:1315-1324.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 1315-1324
-
-
Tuduri, S.1
Crabbé, L.2
Conti, C.3
Tourrière, H.4
Holtgreve-Grez, H.5
Jauch, A.6
Pantesco, V.7
De Vos, J.8
Thomas, A.9
Theillet, C.10
-
76
-
-
84255177502
-
RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability
-
Wahba L., Amon J.D., Koshland D., Vuica-Ross M. RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability. Mol. Cell 2011, 44:978-988.
-
(2011)
Mol. Cell
, vol.44
, pp. 978-988
-
-
Wahba, L.1
Amon, J.D.2
Koshland, D.3
Vuica-Ross, M.4
-
77
-
-
33645823661
-
Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex
-
Wellinger R.E., Prado F., Aguilera A. Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex. Mol. Cell. Biol. 2006, 26:3327-3334.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 3327-3334
-
-
Wellinger, R.E.1
Prado, F.2
Aguilera, A.3
-
78
-
-
1142310578
-
Structural basis of transcription: separation of RNA from DNA by RNA polymerase II
-
Westover K.D., Bushnell D.A., Kornberg R.D. Structural basis of transcription: separation of RNA from DNA by RNA polymerase II. Science 2004, 303:1014-1016.
-
(2004)
Science
, vol.303
, pp. 1014-1016
-
-
Westover, K.D.1
Bushnell, D.A.2
Kornberg, R.D.3
-
79
-
-
84855897667
-
Quantitative model of R-loop forming structures reveals a novel level of RNA-DNA interactome complexity
-
Wongsurawat T., Jenjaroenpun P., Kwoh C.K., Kuznetsov V. Quantitative model of R-loop forming structures reveals a novel level of RNA-DNA interactome complexity. Nucleic Acids Res. 2012, 40:e16.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Wongsurawat, T.1
Jenjaroenpun, P.2
Kwoh, C.K.3
Kuznetsov, V.4
-
80
-
-
0029938513
-
RNA-DNA hybrid formation at the human mitochondrial heavy-strand origin ceases at replication start sites: an implication for RNA-DNA hybrids serving as primers
-
Xu B., Clayton D.A. RNA-DNA hybrid formation at the human mitochondrial heavy-strand origin ceases at replication start sites: an implication for RNA-DNA hybrids serving as primers. EMBO J. 1996, 15:3135-3143.
-
(1996)
EMBO J.
, vol.15
, pp. 3135-3143
-
-
Xu, B.1
Clayton, D.A.2
-
81
-
-
0037650190
-
R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells
-
Yu K., Chedin F., Hsieh C.L., Wilson T.E., Lieber M.R. R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells. Nat. Immunol. 2003, 4:442-451.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 442-451
-
-
Yu, K.1
Chedin, F.2
Hsieh, C.L.3
Wilson, T.E.4
Lieber, M.R.5
|